Eudravigilance C-19 - Tous les vaccins

Liste des effets indésirables (uniquement ceux qui apparaissent dans plus de 50 cas graves)

PT	Décès 18235 (%)	Mise en jeu du pronostic vital 25346 (%)	Invalidité ou incapacité 48879 (%)	Anomalies congénitales 460 (%)	Hospitalisation 85857 (%)	Médicalement significatif 336072 (%)	Cas Graves 514849 (%)
Abdominal discomfort	26 (0.14)	54 (0.21)	281 (0.57)	1 (0.22)	224 (0.26)	1622 (0.48)	2237 (0.43)
Abdominal distension	22 (0.12)	49 (0.19)	180 (0.37)	1 (0.22)	155 (0.18)	784 (0.23)	1204 (0.23)
Abdominal pain	173 (0.95)	357 (1.41)	991 (2.03)	10 (2.17)	1500 (1.75)	4725 (1.41)	7892 (1.53)
Abdominal pain lower	5 (0.03)	29 (0.11)	72 (0.15)	0	192 (0.22)	350 (0.10)	654 (0.13)
Abdominal pain upper	83 (0.46)	182 (0.72)	880 (1.80)	2 (0.43)	789 (0.92)	5604 (1.67)	7585 (1.47)
Abdominal rigidity	3 (0.02)	4 (0.02)	13 (0.03)	0	10 (0.01)	54 (0.02)	84 (0.02)
Abdominal tenderness	3 (0.02)	1 (0.00)	6 (0.01)	0	32 (0.04)	33 (0.01)	80 (0.02)
Abnormal behaviour	7 (0.04)	11 (0.04)	13 (0.03)	0	59 (0.07)	40 (0.01)	139 (0.03)
Abnormal dreams	1 (0.01)	7 (0.03)	50 (0.10)	0	12 (0.01)	335 (0.10)	406 (0.08)
Abnormal faeces	0	3 (0.01)	7 (0.01)	0	65 (0.08)	30 (0.01)	105 (0.02)
Abnormal loss of weight	1 (0.01)	15 (0.06)	35 (0.07)	0	23 (0.03)	49 (0.01)	128 (0.02)
Abnormal sensation in eye	0	0	14 (0.03)	0	11 (0.01)	48 (0.01)	73 (0.01)
Abortion	4 (0.02)	3 (0.01)	0	2 (0.43)	16 (0.02)	44 (0.01)	70 (0.01)
Abortion missed	1 (0.01)	3 (0.01)	0	6 (1.30)	16 (0.02)	68 (0.02)	95 (0.02)
Abortion spontaneous	8 (0.04)	44 (0.17)	61 (0.12)	177 (38.48)	183 (0.21)	1355 (0.40)	1836 (0.36)
Abscess	0	5 (0.02)	14 (0.03)	0	51 (0.06)	57 (0.02)	133 (0.03)
Acne	1 (0.01)	7 (0.03)	22 (0.05)	0	11 (0.01)	184 (0.05)	226 (0.04)
Activated partial thromboplastin time prolonged	5 (0.03)	50 (0.20)	9 (0.02)	0	43 (0.05)	56 (0.02)	168 (0.03)
Acute abdomen	12 (0.07)	2 (0.01)	3 (0.01)	0	19 (0.02)	19 (0.01)	56 (0.01)
Acute coronary syndrome	54 (0.30)	76 (0.30)	2 (0.00)	0	200 (0.23)	20 (0.01)	363 (0.07)
Acute disseminated encephalomyelitis	5 (0.03)	18 (0.07)	27 (0.06)	0	87 (0.10)	26 (0.01)	174 (0.03)
Acute kidney injury	195 (1.07)	160 (0.63)	23 (0.05)	0	469 (0.55)	106 (0.03)	1038 (0.20)
Acute myocardial infarction	309 (1.69)	453 (1.79)	15 (0.03)	0	575 (0.67)	71 (0.02)	1466 (0.28)
Acute polyneuropathy	0	4 (0.02)	3 (0.01)	0	46 (0.05)	9 (0.00)	63 (0.01)
Acute pulmonary oedema	26 (0.14)	21 (0.08)	0	0	58 (0.07)	7 (0.00)	119 (0.02)
Acute respiratory distress syndrome	94 (0.52)	37 (0.15)	1 (0.00)	0	53 (0.06)	22 (0.01)	229 (0.04)
Acute respiratory failure	208 (1.14)	95 (0.37)	4 (0.01)	0	276 (0.32)	14 (0.00)	616 (0.12)
Administration site pain	2 (0.01)	55 (0.22)	59 (0.12)	1 (0.22)	11 (0.01)	70 (0.02)	200 (0.04)
Adnexa uteri pain	0	6 (0.02)	26 (0.05)	1 (0.22)	10 (0.01)	105 (0.03)	148 (0.03)
Adrenal insufficiency	2 (0.01)	10 (0.04)	6 (0.01)	0	23 (0.03)	24 (0.01)	66 (0.01)
Adrenocortical insufficiency acute	1 (0.01)	22 (0.09)	6 (0.01)	0	27 (0.03)	26 (0.01)	82 (0.02)
Adverse drug reaction	1 (0.01)	4 (0.02)	27 (0.06)	0	21 (0.02)	124 (0.04)	179 (0.03)
Adverse event	5 (0.03)	7 (0.03)	6 (0.01)	0	98 (0.11)	47 (0.01)	169 (0.03)
Adverse event following immunisation	113 (0.62)	0	2 (0.00)	0	2 (0.00)	3 (0.00)	120 (0.02)
Adverse reaction	2 (0.01)	7 (0.03)	12 (0.02)	0	18 (0.02)	24 (0.01)	63 (0.01)
Ageusia	23 (0.13)	38 (0.15)	323 (0.66)	1 (0.22)	207 (0.24)	1101 (0.33)	1709 (0.33)
Aggression	9 (0.05)	16 (0.06)	19 (0.04)	0	41 (0.05)	29 (0.01)	115 (0.02)
Agitation	32 (0.18)	46 (0.18)	56 (0.11)	0	96 (0.11)	233 (0.07)	482 (0.09)
Alanine aminotransferase increased	4 (0.02)	19 (0.07)	15 (0.03)	0	63 (0.07)	74 (0.02)	189 (0.04)
Allergy to vaccine	1 (0.01)	27 (0.11)	11 (0.02)	0	57 (0.07)	184 (0.05)	289 (0.06)
Allodynia	0	1 (0.00)	24 (0.05)	0	8 (0.01)	49 (0.01)	85 (0.02)
Alopecia	0	21 (0.08)	126 (0.26)	2 (0.43)	46 (0.05)	477 (0.14)	678 (0.13)
Alopecia areata	0	0	12 (0.02)	0	4 (0.00)	68 (0.02)	85 (0.02)
Altered state of consciousness	72 (0.39)	43 (0.17)	32 (0.07)	0	252 (0.29)	277 (0.08)	764 (0.15)
Amaurosis fugax	0	3 (0.01)	3 (0.01)	0	24 (0.03)	48 (0.01)	80 (0.02)
Amenorrhoea	0	23 (0.09)	184 (0.38)	5 (1.09)	36 (0.04)	756 (0.22)	1009 (0.20)
Amnesia	12 (0.07)	109 (0.43)	253 (0.52)	0	279 (0.32)	471 (0.14)	1146 (0.22)
Anaemia	42 (0.23)	115 (0.45)	70 (0.14)	0	301 (0.35)	231 (0.07)	804 (0.16)
Anal haemorrhage	1 (0.01)	3 (0.01)	7 (0.01)	0	9 (0.01)	38 (0.01)	58 (0.01)
Anal incontinence	9 (0.05)	15 (0.06)	27 (0.06)	0	51 (0.06)	43 (0.01)	155 (0.03)
Anaphylactic reaction	41 (0.22)	1424 (5.62)	72 (0.15)	1 (0.22)	2035 (2.37)	4669 (1.39)	8349 (1.62)
Anaphylactic shock	19 (0.10)	390 (1.54)	20 (0.04)	0	358 (0.42)	475 (0.14)	1290 (0.25)
Anaphylactoid reaction	1 (0.01)	18 (0.07)	3 (0.01)	0	43 (0.05)	209 (0.06)	277 (0.05)
Aneurysm	18 (0.10)	18 (0.07)	3 (0.01)	1 (0.22)	21 (0.02)	11 (0.00)	78 (0.02)
Anger	3 (0.02)	17 (0.07)	21 (0.04)	0	10 (0.01)	85 (0.03)	140 (0.03)
Angina pectoris	17 (0.09)	124 (0.49)	123 (0.25)	1 (0.22)	421 (0.49)	1111 (0.33)	1851 (0.36)
Angina unstable	0	9 (0.04)	3 (0.01)	0	37 (0.04)	23 (0.01)	73 (0.01)
Angioedema	2 (0.01)	183 (0.72)	41 (0.08)	0	271 (0.32)	1716 (0.51)	2256 (0.44)
Angiogram	1 (0.01)	28 (0.11)	7 (0.01)	0	17 (0.02)	14 (0.00)	67 (0.01)
Angiogram cerebral abnormal	4 (0.02)	28 (0.11)	7 (0.01)	0	23 (0.03)	1 (0.00)	63 (0.01)
Angiogram pulmonary abnormal	6 (0.03)	62 (0.24)	1 (0.00)	0	54 (0.06)	2 (0.00)	127 (0.02)
Ankylosing spondylitis	0	0	21 (0.04)	0	6 (0.01)	87 (0.03)	115 (0.02)
Anosmia	16 (0.09)	26 (0.10)	198 (0.41)	0	133 (0.15)	523 (0.16)	909 (0.18)
Anovulatory cycle	0	0	14 (0.03)	0	2 (0.00)	35 (0.01)	52 (0.01)
Anticoagulant therapy	16 (0.09)	146 (0.58)	10 (0.02)	0	117 (0.14)	12 (0.00)	302 (0.06)
Antiphospholipid syndrome	1 (0.01)	19 (0.07)	5 (0.01)	0	17 (0.02)	30 (0.01)	77 (0.01)
Anuria	14 (0.08)	8 (0.03)	1 (0.00)	0	15 (0.02)	22 (0.01)	72 (0.01)
Anxiety	21 (0.12)	139 (0.55)	490 (1.00)	3 (0.65)	477 (0.56)	1750 (0.52)	2916 (0.57)
Aortic aneurysm	18 (0.10)	8 (0.03)	5 (0.01)	0	22 (0.03)	5 (0.00)	62 (0.01)
Aortic dissection	71 (0.39)	39 (0.15)	1 (0.00)	0	17 (0.02)	10 (0.00)	140 (0.03)
Aortic thrombosis	18 (0.10)	35 (0.14)	1 (0.00)	0	30 (0.03)	4 (0.00)	97 (0.02)
Apathy	3 (0.02)	11 (0.04)	49 (0.10)	0	49 (0.06)	107 (0.03)	227 (0.04)
Aphasia	69 (0.38)	228 (0.90)	185 (0.38)	0	542 (0.63)	297 (0.09)	1412 (0.27)
Aphonia	3 (0.02)	21 (0.08)	38 (0.08)	0	49 (0.06)	194 (0.06)	313 (0.06)
Aphthous ulcer	3 (0.02)	7 (0.03)	17 (0.03)	0	19 (0.02)	123 (0.04)	171 (0.03)
Apnoea	35 (0.19)	12 (0.05)	3 (0.01)	0	20 (0.02)	59 (0.02)	144 (0.03)
Appendicitis	2 (0.01)	124 (0.49)	14 (0.03)	0	391 (0.46)	126 (0.04)	662 (0.13)
Appendicitis perforated	0	30 (0.12)	0	0	33 (0.04)	4 (0.00)	67 (0.01)
Appetite disorder	0	1 (0.00)	17 (0.03)	0	6 (0.01)	44 (0.01)	69 (0.01)
Application site erythema	0	0	2 (0.00)	0	2 (0.00)	57 (0.02)	63 (0.01)
Application site pain	1 (0.01)	2 (0.01)	6 (0.01)	0	12 (0.01)	107 (0.03)	131 (0.03)
Areflexia	5 (0.03)	17 (0.07)	28 (0.06)	0	61 (0.07)	5 (0.00)	128 (0.02)
Arrhythmia	113 (0.62)	184 (0.73)	145 (0.30)	0	962 (1.12)	1872 (0.56)	3355 (0.65)
Arterial occlusive disease	7 (0.04)	22 (0.09)	14 (0.03)	0	47 (0.05)	18 (0.01)	111 (0.02)
Arterial thrombosis	16 (0.09)	38 (0.15)	10 (0.02)	0	40 (0.05)	31 (0.01)	145 (0.03)
Arteriosclerosis	42 (0.23)	14 (0.06)	5 (0.01)	0	41 (0.05)	4 (0.00)	116 (0.02)
Arteriosclerosis coronary artery	43 (0.24)	7 (0.03)	0	0	14 (0.02)	1 (0.00)	67 (0.01)
Arthralgia	96 (0.53)	525 (2.07)	8243 (16.86)	7 (1.52)	2037 (2.37)	24467 (7.28)	35529 (6.90)
Arthritis	2 (0.01)	18 (0.07)	339 (0.69)	0	138 (0.16)	718 (0.21)	1224 (0.24)
Arthritis reactive	0	3 (0.01)	52 (0.11)	0	30 (0.03)	129 (0.04)	215 (0.04)
Arthropathy	1 (0.01)	4 (0.02)	53 (0.11)	0	19 (0.02)	74 (0.02)	151 (0.03)
Ascites	20 (0.11)	20 (0.08)	3 (0.01)	2 (0.43)	49 (0.06)	22 (0.01)	136 (0.03)
Aspartate aminotransferase increased	3 (0.02)	12 (0.05)	1 (0.00)	0	53 (0.06)	38 (0.01)	117 (0.02)
Asphyxia	25 (0.14)	15 (0.06)	2 (0.00)	0	13 (0.02)	63 (0.02)	131 (0.03)
Aspiration	43 (0.24)	15 (0.06)	2 (0.00)	0	18 (0.02)	13 (0.00)	109 (0.02)
Asthenia	507 (2.78)	750 (2.96)	2462 (5.04)	3 (0.65)	3435 (4.00)	8436 (2.51)	15942 (3.10)
Asthenopia	0	4 (0.02)	75 (0.15)	0	20 (0.02)	347 (0.10)	448 (0.09)
Asthma	17 (0.09)	155 (0.61)	186 (0.38)	0	335 (0.39)	1054 (0.31)	1764 (0.34)
Asthmatic crisis	0	19 (0.07)	1 (0.00)	0	19 (0.02)	83 (0.02)	125 (0.02)
Asymptomatic COVID-19	12 (0.07)	2 (0.01)	1 (0.00)	0	75 (0.09)	528 (0.16)	623 (0.12)
Ataxia	4 (0.02)	29 (0.11)	50 (0.10)	0	117 (0.14)	45 (0.01)	267 (0.05)
Atelectasis	14 (0.08)	26 (0.10)	7 (0.01)	0	97 (0.11)	12 (0.00)	166 (0.03)
Atrial fibrillation	125 (0.69)	414 (1.63)	131 (0.27)	0	1268 (1.48)	1414 (0.42)	3480 (0.68)
Atrial flutter	5 (0.03)	34 (0.13)	16 (0.03)	0	120 (0.14)	74 (0.02)	260 (0.05)
Atrioventricular block	9 (0.05)	46 (0.18)	7 (0.01)	1 (0.22)	59 (0.07)	27 (0.01)	152 (0.03)
Atrioventricular block complete	12 (0.07)	50 (0.20)	4 (0.01)	0	45 (0.05)	8 (0.00)	125 (0.02)
Atypical pneumonia	7 (0.04)	8 (0.03)	0	0	38 (0.04)	24 (0.01)	82 (0.02)
Auditory disorder	0	4 (0.02)	19 (0.04)	0	17 (0.02)	27 (0.01)	69 (0.01)
Aura	0	0	8 (0.02)	0	10 (0.01)	44 (0.01)	62 (0.01)
Autoimmune disorder	9 (0.05)	27 (0.11)	84 (0.17)	0	71 (0.08)	278 (0.08)	501 (0.10)
Autoimmune haemolytic anaemia	8 (0.04)	24 (0.09)	3 (0.01)	0	52 (0.06)	28 (0.01)	119 (0.02)
Autoimmune hepatitis	5 (0.03)	15 (0.06)	6 (0.01)	0	56 (0.07)	40 (0.01)	124 (0.02)
Autoimmune thyroiditis	0	5 (0.02)	16 (0.03)	0	13 (0.02)	123 (0.04)	159 (0.03)
Autonomic nervous system imbalance	3 (0.02)	15 (0.06)	42 (0.09)	0	14 (0.02)	36 (0.01)	112 (0.02)
Axillary mass	0	3 (0.01)	41 (0.08)	0	17 (0.02)	230 (0.07)	294 (0.06)
Axillary pain	2 (0.01)	22 (0.09)	300 (0.61)	0	75 (0.09)	2324 (0.69)	2730 (0.53)
Back pain	94 (0.52)	281 (1.11)	1512 (3.09)	6 (1.30)	1019 (1.19)	6224 (1.85)	9232 (1.79)
Bacterial infection	11 (0.06)	5 (0.02)	8 (0.02)	0	37 (0.04)	44 (0.01)	110 (0.02)
Balance disorder	26 (0.14)	135 (0.53)	635 (1.30)	1 (0.22)	525 (0.61)	1188 (0.35)	2575 (0.50)
Basedow's disease	0	11 (0.04)	25 (0.05)	0	36 (0.04)	144 (0.04)	220 (0.04)
Bed rest	1 (0.01)	0	32 (0.07)	0	6 (0.01)	22 (0.01)	61 (0.01)
Bedridden	18 (0.10)	24 (0.09)	105 (0.21)	0	50 (0.06)	198 (0.06)	413 (0.08)
Bell's palsy	1 (0.01)	33 (0.13)	461 (0.94)	3 (0.65)	497 (0.58)	3267 (0.97)	4301 (0.84)
Biliary colic	2 (0.01)	4 (0.02)	9 (0.02)	0	21 (0.02)	31 (0.01)	68 (0.01)
Bladder disorder	0	1 (0.00)	14 (0.03)	0	17 (0.02)	24 (0.01)	59 (0.01)
Bladder pain	0	2 (0.01)	20 (0.04)	0	5 (0.01)	68 (0.02)	96 (0.02)
Blepharitis	0	3 (0.01)	8 (0.02)	0	4 (0.00)	37 (0.01)	52 (0.01)
Blepharospasm	0	6 (0.02)	45 (0.09)	0	27 (0.03)	137 (0.04)	217 (0.04)
Blindness	7 (0.04)	67 (0.26)	284 (0.58)	0	159 (0.19)	666 (0.20)	1235 (0.24)
Blindness transient	0	13 (0.05)	20 (0.04)	0	36 (0.04)	209 (0.06)	286 (0.06)
Blindness unilateral	2 (0.01)	24 (0.09)	159 (0.33)	0	62 (0.07)	142 (0.04)	410 (0.08)
Blister	5 (0.03)	36 (0.14)	125 (0.26)	0	122 (0.14)	680 (0.20)	987 (0.19)
Blood bilirubin increased	2 (0.01)	15 (0.06)	2 (0.00)	0	28 (0.03)	15 (0.00)	65 (0.01)
Blood blister	0	9 (0.04)	19 (0.04)	0	22 (0.03)	70 (0.02)	123 (0.02)
Blood cholesterol increased	0	7 (0.03)	8 (0.02)	0	14 (0.02)	26 (0.01)	56 (0.01)
Blood creatine phosphokinase increased	3 (0.02)	13 (0.05)	10 (0.02)	0	121 (0.14)	56 (0.02)	227 (0.04)
Blood creatinine increased	8 (0.04)	18 (0.07)	9 (0.02)	0	55 (0.06)	17 (0.01)	116 (0.02)
Blood disorder	4 (0.02)	8 (0.03)	1 (0.00)	0	13 (0.02)	24 (0.01)	52 (0.01)
Blood fibrinogen increased	2 (0.01)	12 (0.05)	2 (0.00)	0	26 (0.03)	22 (0.01)	76 (0.01)
Blood glucose decreased	6 (0.03)	24 (0.09)	12 (0.02)	0	29 (0.03)	74 (0.02)	153 (0.03)
Blood glucose fluctuation	2 (0.01)	10 (0.04)	7 (0.01)	0	11 (0.01)	40 (0.01)	72 (0.01)
Blood glucose increased	17 (0.09)	40 (0.16)	42 (0.09)	0	112 (0.13)	288 (0.09)	526 (0.10)
Blood iron decreased	1 (0.01)	2 (0.01)	13 (0.03)	0	5 (0.01)	41 (0.01)	69 (0.01)
Blood lactate dehydrogenase increased	2 (0.01)	5 (0.02)	0	0	40 (0.05)	9 (0.00)	65 (0.01)
Blood potassium decreased	1 (0.01)	17 (0.07)	3 (0.01)	0	63 (0.07)	17 (0.01)	108 (0.02)
Blood pressure abnormal	7 (0.04)	22 (0.09)	19 (0.04)	0	54 (0.06)	96 (0.03)	206 (0.04)
Blood pressure decreased	58 (0.32)	168 (0.66)	102 (0.21)	1 (0.22)	383 (0.45)	782 (0.23)	1560 (0.30)
Blood pressure diastolic increased	0	2 (0.01)	8 (0.02)	0	11 (0.01)	27 (0.01)	51 (0.01)
Blood pressure fluctuation	3 (0.02)	48 (0.19)	44 (0.09)	0	90 (0.10)	123 (0.04)	329 (0.06)
Blood pressure increased	31 (0.17)	272 (1.07)	247 (0.51)	1 (0.22)	1034 (1.20)	3092 (0.92)	4789 (0.93)
Blood pressure measurement	0	14 (0.06)	13 (0.03)	0	24 (0.03)	72 (0.02)	124 (0.02)
Blood pressure systolic increased	0	8 (0.03)	3 (0.01)	0	36 (0.04)	101 (0.03)	158 (0.03)
Blood sodium decreased	3 (0.02)	5 (0.02)	4 (0.01)	0	46 (0.05)	8 (0.00)	71 (0.01)
Blood test	4 (0.02)	100 (0.39)	42 (0.09)	0	74 (0.09)	112 (0.03)	332 (0.06)
Blood test abnormal	2 (0.01)	23 (0.09)	39 (0.08)	0	62 (0.07)	86 (0.03)	216 (0.04)
Blood urine	1 (0.01)	3 (0.01)	3 (0.01)	0	10 (0.01)	42 (0.01)	60 (0.01)
Blood urine present	4 (0.02)	13 (0.05)	17 (0.03)	0	41 (0.05)	150 (0.04)	229 (0.04)
Body temperature	0	8 (0.03)	74 (0.15)	0	14 (0.02)	724 (0.22)	822 (0.16)
Body temperature abnormal	1 (0.01)	4 (0.02)	28 (0.06)	0	7 (0.01)	145 (0.04)	187 (0.04)
Body temperature decreased	6 (0.03)	14 (0.06)	38 (0.08)	0	16 (0.02)	163 (0.05)	241 (0.05)
Body temperature fluctuation	1 (0.01)	3 (0.01)	45 (0.09)	0	11 (0.01)	187 (0.06)	247 (0.05)
Body temperature increased	29 (0.16)	30 (0.12)	163 (0.33)	1 (0.22)	234 (0.27)	1210 (0.36)	1684 (0.33)
Bone pain	6 (0.03)	62 (0.24)	354 (0.72)	0	98 (0.11)	1226 (0.36)	1756 (0.34)
Bradycardia	48 (0.26)	105 (0.41)	39 (0.08)	1 (0.22)	210 (0.24)	709 (0.21)	1170 (0.23)
Bradykinesia	1 (0.01)	6 (0.02)	13 (0.03)	0	11 (0.01)	50 (0.01)	83 (0.02)
Bradyphrenia	0	4 (0.02)	37 (0.08)	0	19 (0.02)	110 (0.03)	171 (0.03)
Brain death	67 (0.37)	4 (0.02)	1 (0.00)	0	0	0	78 (0.02)
Brain injury	46 (0.25)	31 (0.12)	11 (0.02)	0	20 (0.02)	29 (0.01)	159 (0.03)
Brain natriuretic peptide increased	3 (0.02)	9 (0.04)	1 (0.00)	0	26 (0.03)	4 (0.00)	51 (0.01)
Brain oedema	77 (0.42)	51 (0.20)	11 (0.02)	0	39 (0.05)	48 (0.01)	255 (0.05)
Brain stem infarction	12 (0.07)	25 (0.10)	11 (0.02)	0	64 (0.07)	9 (0.00)	125 (0.02)
Breast cancer	0	12 (0.05)	7 (0.01)	0	11 (0.01)	109 (0.03)	141 (0.03)
Breast discomfort	0	0	8 (0.02)	0	7 (0.01)	37 (0.01)	52 (0.01)
Breast enlargement	0	4 (0.02)	6 (0.01)	0	4 (0.00)	41 (0.01)	55 (0.01)
Breast mass	0	7 (0.03)	13 (0.03)	1 (0.22)	17 (0.02)	136 (0.04)	177 (0.03)
Breast pain	1 (0.01)	23 (0.09)	120 (0.25)	2 (0.43)	147 (0.17)	888 (0.26)	1189 (0.23)
Breast swelling	0	3 (0.01)	28 (0.06)	0	16 (0.02)	187 (0.06)	235 (0.05)
Breast tenderness	0	3 (0.01)	15 (0.03)	0	7 (0.01)	105 (0.03)	130 (0.03)
Breath sounds abnormal	8 (0.04)	5 (0.02)	2 (0.00)	0	16 (0.02)	22 (0.01)	59 (0.01)
Bronchitis	14 (0.08)	11 (0.04)	18 (0.04)	0	72 (0.08)	111 (0.03)	235 (0.05)
Bronchospasm	6 (0.03)	74 (0.29)	6 (0.01)	0	121 (0.14)	214 (0.06)	441 (0.09)
Bruxism	0	1 (0.00)	7 (0.01)	0	10 (0.01)	35 (0.01)	53 (0.01)
Bundle branch block left	4 (0.02)	8 (0.03)	5 (0.01)	0	23 (0.03)	12 (0.00)	55 (0.01)
Bundle branch block right	2 (0.01)	17 (0.07)	3 (0.01)	0	28 (0.03)	19 (0.01)	74 (0.01)
Burning sensation	5 (0.03)	112 (0.44)	413 (0.84)	4 (0.87)	271 (0.32)	1313 (0.39)	2157 (0.42)
Bursitis	0	5 (0.02)	123 (0.25)	0	30 (0.03)	210 (0.06)	371 (0.07)
C-reactive protein increased	34 (0.19)	41 (0.16)	53 (0.11)	0	389 (0.45)	171 (0.05)	738 (0.14)
COVID-19	1411 (7.74)	382 (1.51)	259 (0.53)	3 (0.65)	4036 (4.70)	20998 (6.25)	27373 (5.32)
COVID-19 immunisation	4 (0.02)	24 (0.09)	83 (0.17)	0	73 (0.09)	173 (0.05)	358 (0.07)
COVID-19 pneumonia	442 (2.42)	147 (0.58)	27 (0.06)	0	874 (1.02)	154 (0.05)	1683 (0.33)
CSF protein increased	0	11 (0.04)	12 (0.02)	0	55 (0.06)	1 (0.00)	91 (0.02)
Candida infection	2 (0.01)	4 (0.02)	11 (0.02)	0	7 (0.01)	70 (0.02)	95 (0.02)
Capillary leak syndrome	10 (0.05)	16 (0.06)	2 (0.00)	0	18 (0.02)	25 (0.01)	74 (0.01)
Cardiac arrest	1102 (6.04)	365 (1.44)	7 (0.01)	0	103 (0.12)	90 (0.03)	1771 (0.34)
Cardiac death	62 (0.34)	1 (0.00)	0	0	1 (0.00)	0	64 (0.01)
Cardiac discomfort	2 (0.01)	23 (0.09)	23 (0.05)	0	63 (0.07)	87 (0.03)	202 (0.04)
Cardiac disorder	68 (0.37)	92 (0.36)	41 (0.08)	0	192 (0.22)	164 (0.05)	582 (0.11)
Cardiac dysfunction	4 (0.02)	17 (0.07)	4 (0.01)	1 (0.22)	20 (0.02)	18 (0.01)	74 (0.01)
Cardiac failure	393 (2.16)	247 (0.97)	56 (0.11)	0	482 (0.56)	178 (0.05)	1425 (0.28)
Cardiac failure acute	134 (0.73)	33 (0.13)	0	0	69 (0.08)	9 (0.00)	248 (0.05)
Cardiac failure chronic	18 (0.10)	6 (0.02)	1 (0.00)	0	25 (0.03)	8 (0.00)	64 (0.01)
Cardiac failure congestive	89 (0.49)	63 (0.25)	17 (0.03)	0	158 (0.18)	53 (0.02)	397 (0.08)
Cardiac fibrillation	1 (0.01)	19 (0.07)	10 (0.02)	1 (0.22)	38 (0.04)	48 (0.01)	124 (0.02)
Cardiac flutter	2 (0.01)	24 (0.09)	62 (0.13)	0	78 (0.09)	1118 (0.33)	1296 (0.25)
Cardiac murmur	3 (0.02)	5 (0.02)	11 (0.02)	2 (0.43)	21 (0.02)	44 (0.01)	87 (0.02)
Cardiac tamponade	29 (0.16)	32 (0.13)	0	0	25 (0.03)	7 (0.00)	97 (0.02)
Cardiac ventricular thrombosis	7 (0.04)	26 (0.10)	2 (0.00)	0	16 (0.02)	4 (0.00)	59 (0.01)
Cardio-respiratory arrest	553 (3.03)	102 (0.40)	0	0	27 (0.03)	13 (0.00)	747 (0.15)
Cardiogenic shock	105 (0.58)	58 (0.23)	1 (0.00)	0	23 (0.03)	13 (0.00)	214 (0.04)
Cardiomegaly	35 (0.19)	45 (0.18)	19 (0.04)	1 (0.22)	98 (0.11)	35 (0.01)	250 (0.05)
Cardiomyopathy	21 (0.12)	49 (0.19)	11 (0.02)	0	75 (0.09)	57 (0.02)	226 (0.04)
Cardiovascular disorder	59 (0.32)	43 (0.17)	102 (0.21)	0	177 (0.21)	145 (0.04)	538 (0.10)
Cardiovascular insufficiency	6 (0.03)	4 (0.02)	2 (0.00)	0	8 (0.01)	29 (0.01)	52 (0.01)
Carditis	4 (0.02)	2 (0.01)	4 (0.01)	0	21 (0.02)	39 (0.01)	74 (0.01)
Carotid artery dissection	3 (0.02)	20 (0.08)	1 (0.00)	0	26 (0.03)	4 (0.00)	55 (0.01)
Carotid artery occlusion	10 (0.05)	20 (0.08)	7 (0.01)	0	30 (0.03)	10 (0.00)	81 (0.02)
Carotid artery stenosis	5 (0.03)	8 (0.03)	5 (0.01)	0	33 (0.04)	6 (0.00)	59 (0.01)
Carotid artery thrombosis	14 (0.08)	31 (0.12)	12 (0.02)	0	24 (0.03)	7 (0.00)	91 (0.02)
Carpal tunnel syndrome	0	1 (0.00)	29 (0.06)	0	9 (0.01)	63 (0.02)	103 (0.02)
Cataract	0	0	19 (0.04)	0	12 (0.01)	69 (0.02)	102 (0.02)
Catarrh	0	4 (0.02)	12 (0.02)	0	4 (0.00)	50 (0.01)	71 (0.01)
Cellulitis	15 (0.08)	32 (0.13)	57 (0.12)	0	215 (0.25)	1678 (0.50)	2030 (0.39)
Central nervous system lesion	3 (0.02)	4 (0.02)	12 (0.02)	0	32 (0.04)	12 (0.00)	69 (0.01)
Cerebellar haemorrhage	11 (0.06)	14 (0.06)	4 (0.01)	0	21 (0.02)	7 (0.00)	62 (0.01)
Cerebellar infarction	8 (0.04)	33 (0.13)	12 (0.02)	0	64 (0.07)	14 (0.00)	135 (0.03)
Cerebellar stroke	5 (0.03)	26 (0.10)	8 (0.02)	0	53 (0.06)	14 (0.00)	107 (0.02)
Cerebral artery embolism	17 (0.09)	33 (0.13)	11 (0.02)	1 (0.22)	18 (0.02)	11 (0.00)	91 (0.02)
Cerebral artery occlusion	12 (0.07)	22 (0.09)	12 (0.02)	0	42 (0.05)	4 (0.00)	96 (0.02)
Cerebral artery thrombosis	14 (0.08)	31 (0.12)	10 (0.02)	0	25 (0.03)	9 (0.00)	92 (0.02)
Cerebral disorder	5 (0.03)	4 (0.02)	9 (0.02)	0	14 (0.02)	13 (0.00)	52 (0.01)
Cerebral haematoma	21 (0.12)	28 (0.11)	2 (0.00)	0	36 (0.04)	2 (0.00)	104 (0.02)
Cerebral haemorrhage	510 (2.80)	346 (1.37)	86 (0.18)	0	415 (0.48)	115 (0.03)	1533 (0.30)
Cerebral infarction	153 (0.84)	361 (1.42)	208 (0.43)	0	929 (1.08)	176 (0.05)	1890 (0.37)
Cerebral ischaemia	23 (0.13)	41 (0.16)	24 (0.05)	0	100 (0.12)	41 (0.01)	240 (0.05)
Cerebral small vessel ischaemic disease	6 (0.03)	4 (0.02)	11 (0.02)	0	31 (0.04)	6 (0.00)	63 (0.01)
Cerebral thrombosis	84 (0.46)	129 (0.51)	31 (0.06)	0	217 (0.25)	86 (0.03)	572 (0.11)
Cerebral venous sinus thrombosis	149 (0.82)	381 (1.50)	34 (0.07)	0	436 (0.51)	119 (0.04)	1143 (0.22)
Cerebral venous thrombosis	59 (0.32)	112 (0.44)	12 (0.02)	0	165 (0.19)	51 (0.02)	416 (0.08)
Cerebrovascular accident	556 (3.05)	1388 (5.48)	675 (1.38)	5 (1.09)	2419 (2.82)	1295 (0.39)	6527 (1.27)
Cerebrovascular disorder	13 (0.07)	11 (0.04)	4 (0.01)	0	32 (0.04)	13 (0.00)	75 (0.01)
Cheilitis	0	5 (0.02)	5 (0.01)	0	8 (0.01)	37 (0.01)	56 (0.01)
Chest X-ray	3 (0.02)	34 (0.13)	10 (0.02)	0	40 (0.05)	37 (0.01)	124 (0.02)
Chest X-ray abnormal	12 (0.07)	23 (0.09)	3 (0.01)	0	59 (0.07)	8 (0.00)	107 (0.02)
Chest discomfort	61 (0.33)	456 (1.80)	665 (1.36)	4 (0.87)	1849 (2.15)	3530 (1.05)	6689 (1.30)
Chest pain	290 (1.59)	1460 (5.76)	1649 (3.37)	4 (0.87)	4914 (5.72)	7866 (2.34)	16510 (3.21)
Chillblains	0	1 (0.00)	7 (0.01)	0	2 (0.00)	70 (0.02)	80 (0.02)
Chills	206 (1.13)	887 (3.50)	9084 (18.58)	14 (3.04)	3417 (3.98)	39904 (11.87)	53725 (10.44)
Choking	15 (0.08)	26 (0.10)	6 (0.01)	0	22 (0.03)	136 (0.04)	221 (0.04)
Choking sensation	1 (0.01)	19 (0.07)	10 (0.02)	0	27 (0.03)	53 (0.02)	116 (0.02)
Cholecystitis	4 (0.02)	5 (0.02)	6 (0.01)	0	59 (0.07)	23 (0.01)	105 (0.02)
Cholecystitis acute	3 (0.02)	6 (0.02)	2 (0.00)	0	31 (0.04)	6 (0.00)	51 (0.01)
Cholelithiasis	5 (0.03)	8 (0.03)	6 (0.01)	0	57 (0.07)	20 (0.01)	102 (0.02)
Cholestasis	3 (0.02)	1 (0.00)	2 (0.00)	0	29 (0.03)	16 (0.00)	53 (0.01)
Chromaturia	4 (0.02)	24 (0.09)	23 (0.05)	0	68 (0.08)	125 (0.04)	250 (0.05)
Chronic fatigue syndrome	0	3 (0.01)	123 (0.25)	0	23 (0.03)	123 (0.04)	275 (0.05)
Chronic inflammatory demyelinating polyradiculoneuropathy	0	3 (0.01)	27 (0.06)	0	31 (0.04)	20 (0.01)	86 (0.02)
Chronic kidney disease	23 (0.13)	10 (0.04)	4 (0.01)	0	50 (0.06)	27 (0.01)	121 (0.02)
Chronic obstructive pulmonary disease	68 (0.37)	33 (0.13)	13 (0.03)	0	139 (0.16)	57 (0.02)	326 (0.06)
Circulatory collapse	153 (0.84)	113 (0.45)	23 (0.05)	0	241 (0.28)	420 (0.12)	1017 (0.20)
Clumsiness	0	3 (0.01)	27 (0.06)	0	12 (0.01)	43 (0.01)	87 (0.02)
Cluster headache	3 (0.02)	14 (0.06)	128 (0.26)	0	39 (0.05)	638 (0.19)	822 (0.16)
Coagulopathy	48 (0.26)	83 (0.33)	63 (0.13)	1 (0.22)	113 (0.13)	125 (0.04)	449 (0.09)
Cognitive disorder	22 (0.12)	36 (0.14)	218 (0.45)	0	101 (0.12)	245 (0.07)	646 (0.13)
Cold sweat	31 (0.17)	114 (0.45)	294 (0.60)	1 (0.22)	340 (0.40)	1933 (0.58)	2755 (0.54)
Cold-stimulus headache	0	6 (0.02)	16 (0.03)	0	4 (0.00)	72 (0.02)	98 (0.02)
Colitis	6 (0.03)	24 (0.09)	19 (0.04)	0	119 (0.14)	99 (0.03)	268 (0.05)
Colitis ischaemic	11 (0.06)	15 (0.06)	1 (0.00)	0	81 (0.09)	41 (0.01)	152 (0.03)
Colitis ulcerative	0	15 (0.06)	42 (0.09)	0	73 (0.09)	267 (0.08)	401 (0.08)
Coma	86 (0.47)	89 (0.35)	11 (0.02)	0	59 (0.07)	27 (0.01)	325 (0.06)
Coma scale abnormal	17 (0.09)	14 (0.06)	3 (0.01)	0	13 (0.02)	11 (0.00)	71 (0.01)
Communication disorder	9 (0.05)	14 (0.06)	5 (0.01)	0	28 (0.03)	10 (0.00)	80 (0.02)
Complex regional pain syndrome	0	1 (0.00)	20 (0.04)	0	7 (0.01)	25 (0.01)	54 (0.01)
Computerised tomogram	9 (0.05)	84 (0.33)	24 (0.05)	1 (0.22)	72 (0.08)	62 (0.02)	252 (0.05)
Computerised tomogram abnormal	4 (0.02)	27 (0.11)	2 (0.00)	0	26 (0.03)	22 (0.01)	82 (0.02)
Computerised tomogram head	1 (0.01)	25 (0.10)	6 (0.01)	1 (0.22)	44 (0.05)	28 (0.01)	106 (0.02)
Computerised tomogram head abnormal	19 (0.10)	44 (0.17)	13 (0.03)	0	53 (0.06)	2 (0.00)	131 (0.03)
Computerised tomogram head normal	2 (0.01)	13 (0.05)	13 (0.03)	0	32 (0.04)	3 (0.00)	63 (0.01)
Computerised tomogram thorax	3 (0.02)	23 (0.09)	1 (0.00)	0	31 (0.04)	26 (0.01)	84 (0.02)
Computerised tomogram thorax abnormal	8 (0.04)	98 (0.39)	5 (0.01)	0	57 (0.07)	5 (0.00)	173 (0.03)
Concomitant disease aggravated	17 (0.09)	1 (0.00)	15 (0.03)	0	24 (0.03)	27 (0.01)	91 (0.02)
Concussion	1 (0.01)	10 (0.04)	13 (0.03)	0	39 (0.05)	27 (0.01)	95 (0.02)
Condition aggravated	232 (1.27)	262 (1.03)	726 (1.49)	2 (0.43)	912 (1.06)	1690 (0.50)	3931 (0.76)
Confusional state	161 (0.88)	374 (1.48)	738 (1.51)	1 (0.22)	1087 (1.27)	2124 (0.63)	4613 (0.90)
Congestive cardiomyopathy	15 (0.08)	20 (0.08)	5 (0.01)	0	36 (0.04)	14 (0.00)	99 (0.02)
Conjunctival haemorrhage	2 (0.01)	6 (0.02)	12 (0.02)	0	19 (0.02)	286 (0.09)	329 (0.06)
Conjunctival hyperaemia	2 (0.01)	5 (0.02)	2 (0.00)	0	27 (0.03)	40 (0.01)	77 (0.01)
Conjunctivitis	2 (0.01)	7 (0.03)	23 (0.05)	1 (0.22)	34 (0.04)	130 (0.04)	197 (0.04)
Constipation	11 (0.06)	31 (0.12)	138 (0.28)	0	156 (0.18)	449 (0.13)	800 (0.16)
Contusion	35 (0.19)	193 (0.76)	356 (0.73)	1 (0.22)	424 (0.49)	2325 (0.69)	3384 (0.66)
Conversion disorder	0	2 (0.01)	33 (0.07)	0	36 (0.04)	24 (0.01)	97 (0.02)
Coordination abnormal	11 (0.06)	23 (0.09)	86 (0.18)	1 (0.22)	92 (0.11)	142 (0.04)	365 (0.07)
Coronary artery disease	50 (0.27)	36 (0.14)	6 (0.01)	1 (0.22)	75 (0.09)	10 (0.00)	192 (0.04)
Coronary artery occlusion	16 (0.09)	59 (0.23)	4 (0.01)	0	43 (0.05)	9 (0.00)	140 (0.03)
Coronary artery stenosis	10 (0.05)	22 (0.09)	2 (0.00)	1 (0.22)	25 (0.03)	9 (0.00)	73 (0.01)
Coronary artery thrombosis	35 (0.19)	71 (0.28)	2 (0.00)	0	26 (0.03)	9 (0.00)	156 (0.03)
Costochondritis	0	2 (0.01)	41 (0.08)	0	34 (0.04)	116 (0.03)	195 (0.04)
Cough	464 (2.54)	486 (1.92)	965 (1.97)	2 (0.43)	2338 (2.72)	5307 (1.58)	9743 (1.89)
Craniocerebral injury	10 (0.05)	3 (0.01)	6 (0.01)	0	21 (0.02)	18 (0.01)	61 (0.01)
Crohn's disease	0	5 (0.02)	41 (0.08)	0	42 (0.05)	173 (0.05)	268 (0.05)
Crying	1 (0.01)	18 (0.07)	87 (0.18)	0	46 (0.05)	347 (0.10)	502 (0.10)
Cutaneous vasculitis	2 (0.01)	2 (0.01)	3 (0.01)	0	94 (0.11)	121 (0.04)	226 (0.04)
Cyanosis	78 (0.43)	73 (0.29)	46 (0.09)	0	184 (0.21)	192 (0.06)	616 (0.12)
Cyst	0	4 (0.02)	12 (0.02)	1 (0.22)	14 (0.02)	45 (0.01)	78 (0.02)
Cystitis	4 (0.02)	8 (0.03)	22 (0.05)	0	55 (0.06)	173 (0.05)	267 (0.05)
Deafness	2 (0.01)	23 (0.09)	362 (0.74)	0	97 (0.11)	1109 (0.33)	1627 (0.32)
Deafness bilateral	0	0	39 (0.08)	0	4 (0.00)	54 (0.02)	98 (0.02)
Deafness neurosensory	1 (0.01)	4 (0.02)	117 (0.24)	0	14 (0.02)	137 (0.04)	279 (0.05)
Deafness unilateral	0	5 (0.02)	260 (0.53)	0	46 (0.05)	471 (0.14)	797 (0.15)
Death	4901 (26.88)	4 (0.02)	0	0	1 (0.00)	3 (0.00)	4910 (0.95)
Decreased activity	5 (0.03)	2 (0.01)	17 (0.03)	0	10 (0.01)	23 (0.01)	61 (0.01)
Decreased appetite	272 (1.49)	211 (0.83)	1322 (2.70)	2 (0.43)	1025 (1.19)	6201 (1.85)	9179 (1.78)
Deep vein thrombosis	153 (0.84)	1341 (5.29)	187 (0.38)	2 (0.43)	2282 (2.66)	4026 (1.20)	8193 (1.59)
Dehydration	57 (0.31)	87 (0.34)	128 (0.26)	0	462 (0.54)	691 (0.21)	1479 (0.29)
Delirium	32 (0.18)	62 (0.24)	113 (0.23)	0	156 (0.18)	652 (0.19)	1063 (0.21)
Delusion	4 (0.02)	9 (0.04)	23 (0.05)	0	32 (0.04)	52 (0.02)	124 (0.02)
Dementia	26 (0.14)	14 (0.06)	33 (0.07)	0	44 (0.05)	99 (0.03)	250 (0.05)
Demyelinating polyneuropathy	1 (0.01)	12 (0.05)	13 (0.03)	0	37 (0.04)	9 (0.00)	75 (0.01)
Demyelination	2 (0.01)	7 (0.03)	51 (0.10)	0	64 (0.07)	50 (0.01)	185 (0.04)
Depressed level of consciousness	112 (0.61)	122 (0.48)	35 (0.07)	0	327 (0.38)	688 (0.20)	1419 (0.28)
Depressed mood	3 (0.02)	22 (0.09)	177 (0.36)	1 (0.22)	40 (0.05)	798 (0.24)	1047 (0.20)
Depression	7 (0.04)	69 (0.27)	272 (0.56)	1 (0.22)	115 (0.13)	743 (0.22)	1224 (0.24)
Dermatitis	1 (0.01)	8 (0.03)	38 (0.08)	0	27 (0.03)	233 (0.07)	310 (0.06)
Dermatitis allergic	0	21 (0.08)	44 (0.09)	0	54 (0.06)	377 (0.11)	502 (0.10)
Dermatitis atopic	0	0	15 (0.03)	0	10 (0.01)	64 (0.02)	89 (0.02)
Dermatitis bullous	3 (0.02)	3 (0.01)	12 (0.02)	0	27 (0.03)	122 (0.04)	168 (0.03)
Dermatitis contact	0	3 (0.01)	6 (0.01)	0	2 (0.00)	40 (0.01)	51 (0.01)
Dermatomyositis	0	10 (0.04)	8 (0.02)	0	24 (0.03)	18 (0.01)	61 (0.01)
Diabetes mellitus	24 (0.13)	37 (0.15)	36 (0.07)	0	75 (0.09)	240 (0.07)	431 (0.08)
Diabetes mellitus inadequate control	6 (0.03)	6 (0.02)	5 (0.01)	0	19 (0.02)	127 (0.04)	168 (0.03)
Diabetic ketoacidosis	15 (0.08)	43 (0.17)	6 (0.01)	0	59 (0.07)	31 (0.01)	165 (0.03)
Diarrhoea	243 (1.33)	406 (1.60)	1897 (3.88)	4 (0.87)	1987 (2.31)	10556 (3.14)	15273 (2.97)
Diarrhoea haemorrhagic	3 (0.02)	15 (0.06)	7 (0.01)	0	42 (0.05)	156 (0.05)	228 (0.04)
Diplegia	4 (0.02)	19 (0.07)	50 (0.10)	0	46 (0.05)	97 (0.03)	227 (0.04)
Diplopia	3 (0.02)	63 (0.25)	249 (0.51)	0	367 (0.43)	445 (0.13)	1150 (0.22)
Disability	2 (0.01)	7 (0.03)	44 (0.09)	0	8 (0.01)	19 (0.01)	83 (0.02)
Discomfort	31 (0.17)	59 (0.23)	233 (0.48)	1 (0.22)	254 (0.30)	988 (0.29)	1596 (0.31)
Disease progression	10 (0.05)	2 (0.01)	8 (0.02)	0	10 (0.01)	24 (0.01)	56 (0.01)
Disease recurrence	18 (0.10)	67 (0.26)	120 (0.25)	0	179 (0.21)	880 (0.26)	1293 (0.25)
Disorganised speech	1 (0.01)	5 (0.02)	7 (0.01)	1 (0.22)	20 (0.02)	29 (0.01)	65 (0.01)
Disorientation	33 (0.18)	77 (0.30)	214 (0.44)	0	299 (0.35)	828 (0.25)	1483 (0.29)
Disseminated intravascular coagulation	63 (0.35)	59 (0.23)	1 (0.00)	0	33 (0.04)	10 (0.00)	184 (0.04)
Dissociation	0	5 (0.02)	17 (0.03)	0	11 (0.01)	71 (0.02)	106 (0.02)
Disturbance in attention	11 (0.06)	67 (0.26)	458 (0.94)	1 (0.22)	342 (0.40)	1105 (0.33)	2015 (0.39)
Diverticulitis	5 (0.03)	7 (0.03)	10 (0.02)	0	99 (0.12)	130 (0.04)	257 (0.05)
Dizziness	208 (1.14)	1298 (5.12)	4905 (10.03)	10 (2.17)	5782 (6.73)	24460 (7.28)	37002 (7.19)
Dizziness exertional	0	3 (0.01)	25 (0.05)	0	6 (0.01)	119 (0.04)	155 (0.03)
Dizziness postural	1 (0.01)	15 (0.06)	298 (0.61)	0	105 (0.12)	1987 (0.59)	2409 (0.47)
Drooling	5 (0.03)	4 (0.02)	14 (0.03)	0	26 (0.03)	34 (0.01)	88 (0.02)
Drug eruption	0	3 (0.01)	7 (0.01)	0	39 (0.05)	98 (0.03)	148 (0.03)
Drug hypersensitivity	1 (0.01)	22 (0.09)	14 (0.03)	0	37 (0.04)	120 (0.04)	201 (0.04)
Drug ineffective	243 (1.33)	121 (0.48)	85 (0.17)	0	550 (0.64)	5891 (1.75)	7108 (1.38)
Drug interaction	6 (0.03)	9 (0.04)	8 (0.02)	0	39 (0.05)	79 (0.02)	143 (0.03)
Drug reaction with eosinophilia and systemic symptoms	1 (0.01)	11 (0.04)	5 (0.01)	0	30 (0.03)	15 (0.00)	62 (0.01)
Dry eye	0	4 (0.02)	89 (0.18)	0	32 (0.04)	296 (0.09)	424 (0.08)
Dry mouth	1 (0.01)	52 (0.21)	189 (0.39)	0	153 (0.18)	1060 (0.32)	1468 (0.29)
Dry skin	0	7 (0.03)	56 (0.11)	0	21 (0.02)	353 (0.11)	441 (0.09)
Dry throat	1 (0.01)	14 (0.06)	45 (0.09)	0	24 (0.03)	267 (0.08)	354 (0.07)
Dysaesthesia	0	10 (0.04)	29 (0.06)	0	96 (0.11)	150 (0.04)	294 (0.06)
Dysarthria	63 (0.35)	198 (0.78)	220 (0.45)	0	620 (0.72)	433 (0.13)	1602 (0.31)
Dysentery	0	6 (0.02)	18 (0.04)	0	12 (0.01)	143 (0.04)	179 (0.03)
Dysgeusia	6 (0.03)	47 (0.19)	256 (0.52)	1 (0.22)	141 (0.16)	1610 (0.48)	2077 (0.40)
Dysgraphia	0	7 (0.03)	14 (0.03)	0	12 (0.01)	16 (0.00)	53 (0.01)
Dyskinesia	6 (0.03)	21 (0.08)	86 (0.18)	1 (0.22)	147 (0.17)	190 (0.06)	467 (0.09)
Dyslalia	0	3 (0.01)	9 (0.02)	0	51 (0.06)	6 (0.00)	82 (0.02)
Dysmenorrhoea	0	15 (0.06)	383 (0.78)	2 (0.43)	87 (0.10)	3327 (0.99)	3825 (0.74)
Dyspepsia	14 (0.08)	54 (0.21)	176 (0.36)	0	113 (0.13)	871 (0.26)	1242 (0.24)
Dysphagia	70 (0.38)	224 (0.88)	191 (0.39)	2 (0.43)	467 (0.54)	696 (0.21)	1733 (0.34)
Dysphemia	2 (0.01)	11 (0.04)	18 (0.04)	0	30 (0.03)	38 (0.01)	102 (0.02)
Dysphonia	8 (0.04)	94 (0.37)	107 (0.22)	0	221 (0.26)	449 (0.13)	912 (0.18)
Dysphoria	3 (0.02)	8 (0.03)	0	0	64 (0.07)	116 (0.03)	199 (0.04)
Dyspnoea	1420 (7.79)	2954 (11.65)	2550 (5.22)	7 (1.52)	8122 (9.46)	11476 (3.41)	27363 (5.31)
Dyspnoea at rest	3 (0.02)	8 (0.03)	11 (0.02)	0	41 (0.05)	93 (0.03)	162 (0.03)
Dyspnoea exertional	32 (0.18)	129 (0.51)	105 (0.21)	0	391 (0.46)	335 (0.10)	1047 (0.20)
Dysstasia	13 (0.07)	68 (0.27)	207 (0.42)	0	250 (0.29)	299 (0.09)	877 (0.17)
Dystonia	1 (0.01)	5 (0.02)	13 (0.03)	0	15 (0.02)	60 (0.02)	99 (0.02)
Dysuria	10 (0.05)	20 (0.08)	41 (0.08)	0	101 (0.12)	160 (0.05)	339 (0.07)
Ear congestion	0	4 (0.02)	25 (0.05)	0	5 (0.01)	44 (0.01)	78 (0.02)
Ear discomfort	0	15 (0.06)	162 (0.33)	0	80 (0.09)	275 (0.08)	548 (0.11)
Ear disorder	0	2 (0.01)	25 (0.05)	0	7 (0.01)	38 (0.01)	74 (0.01)
Ear infection	1 (0.01)	7 (0.03)	42 (0.09)	0	19 (0.02)	210 (0.06)	286 (0.06)
Ear pain	3 (0.02)	33 (0.13)	478 (0.98)	1 (0.22)	180 (0.21)	2176 (0.65)	2893 (0.56)
Ear swelling	0	8 (0.03)	11 (0.02)	0	23 (0.03)	96 (0.03)	141 (0.03)
Eating disorder	7 (0.04)	8 (0.03)	23 (0.05)	0	44 (0.05)	56 (0.02)	149 (0.03)
Ecchymosis	2 (0.01)	22 (0.09)	9 (0.02)	0	93 (0.11)	111 (0.03)	250 (0.05)
Echocardiogram	5 (0.03)	62 (0.24)	6 (0.01)	1 (0.22)	60 (0.07)	10 (0.00)	144 (0.03)
Echocardiogram abnormal	6 (0.03)	20 (0.08)	2 (0.00)	1 (0.22)	25 (0.03)	6 (0.00)	61 (0.01)
Ectopic pregnancy	0	16 (0.06)	3 (0.01)	2 (0.43)	11 (0.01)	21 (0.01)	54 (0.01)
Eczema	1 (0.01)	7 (0.03)	72 (0.15)	0	66 (0.08)	451 (0.13)	603 (0.12)
Ejection fraction decreased	10 (0.05)	19 (0.07)	7 (0.01)	0	38 (0.04)	10 (0.00)	96 (0.02)
Electric shock sensation	1 (0.01)	16 (0.06)	81 (0.17)	0	30 (0.03)	128 (0.04)	259 (0.05)
Electrocardiogram	3 (0.02)	62 (0.24)	12 (0.02)	0	44 (0.05)	59 (0.02)	180 (0.03)
Electrocardiogram ST segment elevation	1 (0.01)	14 (0.06)	2 (0.00)	0	78 (0.09)	56 (0.02)	167 (0.03)
Electrocardiogram abnormal	3 (0.02)	34 (0.13)	8 (0.02)	0	98 (0.11)	55 (0.02)	209 (0.04)
Electrocardiogram normal	1 (0.01)	14 (0.06)	5 (0.01)	0	23 (0.03)	12 (0.00)	55 (0.01)
Embolic stroke	12 (0.07)	36 (0.14)	22 (0.05)	0	63 (0.07)	19 (0.01)	159 (0.03)
Embolism	56 (0.31)	143 (0.56)	53 (0.11)	0	157 (0.18)	182 (0.05)	609 (0.12)
Embolism arterial	5 (0.03)	15 (0.06)	4 (0.01)	0	20 (0.02)	8 (0.00)	52 (0.01)
Embolism venous	7 (0.04)	17 (0.07)	3 (0.01)	0	40 (0.05)	22 (0.01)	90 (0.02)
Emotional disorder	0	3 (0.01)	32 (0.07)	0	8 (0.01)	141 (0.04)	184 (0.04)
Emotional distress	1 (0.01)	20 (0.08)	53 (0.11)	0	26 (0.03)	118 (0.04)	223 (0.04)
Emphysema	15 (0.08)	7 (0.03)	4 (0.01)	0	24 (0.03)	9 (0.00)	61 (0.01)
Encephalitis	16 (0.09)	85 (0.34)	30 (0.06)	0	208 (0.24)	68 (0.02)	422 (0.08)
Encephalitis autoimmune	3 (0.02)	13 (0.05)	5 (0.01)	0	33 (0.04)	2 (0.00)	59 (0.01)
Encephalopathy	28 (0.15)	32 (0.13)	17 (0.03)	0	121 (0.14)	36 (0.01)	255 (0.05)
Endocarditis	10 (0.05)	20 (0.08)	2 (0.00)	0	34 (0.04)	18 (0.01)	91 (0.02)
Endometriosis	0	1 (0.00)	26 (0.05)	0	16 (0.02)	132 (0.04)	176 (0.03)
Endotracheal intubation	52 (0.29)	43 (0.17)	1 (0.00)	0	37 (0.04)	0	139 (0.03)
Enlarged uvula	0	9 (0.04)	1 (0.00)	0	13 (0.02)	31 (0.01)	55 (0.01)
Enteritis	2 (0.01)	6 (0.02)	3 (0.01)	0	28 (0.03)	11 (0.00)	52 (0.01)
Enterocolitis	2 (0.01)	4 (0.02)	3 (0.01)	0	15 (0.02)	24 (0.01)	51 (0.01)
Enuresis	1 (0.01)	5 (0.02)	14 (0.03)	0	9 (0.01)	54 (0.02)	83 (0.02)
Eosinophilia	2 (0.01)	9 (0.04)	7 (0.01)	0	39 (0.05)	28 (0.01)	92 (0.02)
Epididymitis	0	0	6 (0.01)	0	9 (0.01)	43 (0.01)	58 (0.01)
Epigastric discomfort	2 (0.01)	5 (0.02)	5 (0.01)	0	21 (0.02)	31 (0.01)	65 (0.01)
Epilepsy	30 (0.16)	154 (0.61)	80 (0.16)	0	522 (0.61)	686 (0.20)	1497 (0.29)
Epistaxis	34 (0.19)	167 (0.66)	209 (0.43)	2 (0.43)	407 (0.47)	1714 (0.51)	2560 (0.50)
Epstein-Barr virus infection reactivation	0	1 (0.00)	5 (0.01)	0	14 (0.02)	34 (0.01)	57 (0.01)
Erectile dysfunction	1 (0.01)	8 (0.03)	62 (0.13)	0	15 (0.02)	230 (0.07)	319 (0.06)
Eructation	1 (0.01)	8 (0.03)	33 (0.07)	0	25 (0.03)	103 (0.03)	174 (0.03)
Erysipelas	3 (0.02)	8 (0.03)	11 (0.02)	0	69 (0.08)	165 (0.05)	261 (0.05)
Erythema	28 (0.15)	263 (1.04)	389 (0.80)	4 (0.87)	1037 (1.21)	4230 (1.26)	6044 (1.17)
Erythema multiforme	1 (0.01)	7 (0.03)	6 (0.01)	0	76 (0.09)	369 (0.11)	463 (0.09)
Erythema nodosum	0	2 (0.01)	12 (0.02)	0	27 (0.03)	85 (0.03)	127 (0.02)
Erythema of eyelid	0	2 (0.01)	5 (0.01)	0	11 (0.01)	48 (0.01)	66 (0.01)
Euphoric mood	0	5 (0.02)	10 (0.02)	0	7 (0.01)	77 (0.02)	99 (0.02)
Exercise tolerance decreased	1 (0.01)	23 (0.09)	98 (0.20)	0	80 (0.09)	102 (0.03)	326 (0.06)
Exposure during pregnancy	5 (0.03)	25 (0.10)	7 (0.01)	20 (4.35)	105 (0.12)	168 (0.05)	341 (0.07)
Exposure to SARS-CoV-2	11 (0.06)	2 (0.01)	4 (0.01)	0	54 (0.06)	26 (0.01)	100 (0.02)
Exposure via breast milk	2 (0.01)	3 (0.01)	9 (0.02)	2 (0.43)	13 (0.02)	215 (0.06)	245 (0.05)
Extensive swelling of vaccinated limb	1 (0.01)	16 (0.06)	552 (1.13)	0	26 (0.03)	136 (0.04)	732 (0.14)
Extrasystoles	4 (0.02)	43 (0.17)	81 (0.17)	1 (0.22)	120 (0.14)	348 (0.10)	605 (0.12)
Eye discharge	1 (0.01)	1 (0.00)	14 (0.03)	1 (0.22)	3 (0.00)	39 (0.01)	60 (0.01)
Eye disorder	2 (0.01)	7 (0.03)	51 (0.10)	0	64 (0.07)	131 (0.04)	257 (0.05)
Eye haemorrhage	1 (0.01)	8 (0.03)	40 (0.08)	0	33 (0.04)	390 (0.12)	486 (0.09)
Eye infection	0	2 (0.01)	14 (0.03)	1 (0.22)	12 (0.01)	51 (0.02)	81 (0.02)
Eye inflammation	1 (0.01)	3 (0.01)	21 (0.04)	0	25 (0.03)	58 (0.02)	112 (0.02)
Eye injury	1 (0.01)	7 (0.03)	29 (0.06)	0	13 (0.02)	43 (0.01)	93 (0.02)
Eye irritation	0	14 (0.06)	74 (0.15)	0	30 (0.03)	270 (0.08)	393 (0.08)
Eye movement disorder	4 (0.02)	23 (0.09)	44 (0.09)	0	70 (0.08)	92 (0.03)	247 (0.05)
Eye oedema	1 (0.01)	5 (0.02)	13 (0.03)	0	8 (0.01)	53 (0.02)	82 (0.02)
Eye pain	2 (0.01)	81 (0.32)	711 (1.45)	0	264 (0.31)	3146 (0.94)	4226 (0.82)
Eye pruritus	0	26 (0.10)	50 (0.10)	0	55 (0.06)	383 (0.11)	523 (0.10)
Eye swelling	0	61 (0.24)	111 (0.23)	1 (0.22)	101 (0.12)	819 (0.24)	1106 (0.21)
Eyelid disorder	0	0	22 (0.05)	0	11 (0.01)	17 (0.01)	53 (0.01)
Eyelid function disorder	0	3 (0.01)	20 (0.04)	0	15 (0.02)	24 (0.01)	64 (0.01)
Eyelid oedema	1 (0.01)	14 (0.06)	15 (0.03)	0	68 (0.08)	187 (0.06)	291 (0.06)
Eyelid ptosis	2 (0.01)	13 (0.05)	45 (0.09)	0	73 (0.09)	117 (0.03)	262 (0.05)
Face injury	1 (0.01)	3 (0.01)	4 (0.01)	0	14 (0.02)	33 (0.01)	56 (0.01)
Face oedema	3 (0.02)	50 (0.20)	27 (0.06)	0	137 (0.16)	345 (0.10)	571 (0.11)
Facial asymmetry	2 (0.01)	2 (0.01)	5 (0.01)	0	34 (0.04)	27 (0.01)	72 (0.01)
Facial bones fracture	0	4 (0.02)	6 (0.01)	0	20 (0.02)	22 (0.01)	54 (0.01)
Facial discomfort	0	4 (0.02)	8 (0.02)	0	11 (0.01)	43 (0.01)	68 (0.01)
Facial pain	0	11 (0.04)	136 (0.28)	0	71 (0.08)	409 (0.12)	633 (0.12)
Facial paralysis	18 (0.10)	145 (0.57)	405 (0.83)	3 (0.65)	1076 (1.25)	2853 (0.85)	4596 (0.89)
Facial paresis	5 (0.03)	59 (0.23)	156 (0.32)	0	463 (0.54)	426 (0.13)	1132 (0.22)
Facial spasm	0	2 (0.01)	24 (0.05)	0	11 (0.01)	54 (0.02)	91 (0.02)
Faeces discoloured	7 (0.04)	12 (0.05)	18 (0.04)	0	44 (0.05)	68 (0.02)	158 (0.03)
Faeces soft	1 (0.01)	1 (0.00)	5 (0.01)	0	14 (0.02)	36 (0.01)	58 (0.01)
Fall	202 (1.11)	230 (0.91)	246 (0.50)	0	1025 (1.19)	814 (0.24)	2700 (0.52)
Fatigue	477 (2.62)	1352 (5.33)	14437 (29.54)	20 (4.35)	5018 (5.84)	51311 (15.27)	73018 (14.18)
Fear	1 (0.01)	22 (0.09)	43 (0.09)	0	31 (0.04)	95 (0.03)	194 (0.04)
Febrile convulsion	5 (0.03)	8 (0.03)	19 (0.04)	1 (0.22)	56 (0.07)	133 (0.04)	224 (0.04)
Feeding disorder	17 (0.09)	36 (0.14)	106 (0.22)	0	105 (0.12)	279 (0.08)	569 (0.11)
Feeling abnormal	67 (0.37)	257 (1.01)	1056 (2.16)	3 (0.65)	940 (1.09)	4387 (1.31)	6829 (1.33)
Feeling cold	17 (0.09)	103 (0.41)	681 (1.39)	1 (0.22)	339 (0.39)	4877 (1.45)	6037 (1.17)
Feeling drunk	1 (0.01)	3 (0.01)	33 (0.07)	1 (0.22)	15 (0.02)	177 (0.05)	231 (0.04)
Feeling hot	17 (0.09)	138 (0.54)	426 (0.87)	2 (0.43)	606 (0.71)	3031 (0.90)	4267 (0.83)
Feeling jittery	0	7 (0.03)	7 (0.01)	0	32 (0.04)	82 (0.02)	134 (0.03)
Feeling of body temperature change	7 (0.04)	17 (0.07)	206 (0.42)	0	94 (0.11)	1055 (0.31)	1382 (0.27)
Feeling of despair	0	3 (0.01)	10 (0.02)	0	5 (0.01)	35 (0.01)	54 (0.01)
Fibrin D dimer	1 (0.01)	22 (0.09)	4 (0.01)	0	33 (0.04)	27 (0.01)	88 (0.02)
Fibrin D dimer increased	53 (0.29)	148 (0.58)	33 (0.07)	0	544 (0.63)	354 (0.11)	1310 (0.25)
Fibromyalgia	1 (0.01)	9 (0.04)	164 (0.34)	0	30 (0.03)	296 (0.09)	505 (0.10)
Fine motor skill dysfunction	2 (0.01)	8 (0.03)	38 (0.08)	0	25 (0.03)	31 (0.01)	108 (0.02)
Flank pain	6 (0.03)	28 (0.11)	48 (0.10)	0	88 (0.10)	131 (0.04)	307 (0.06)
Flatulence	2 (0.01)	13 (0.05)	71 (0.15)	0	37 (0.04)	403 (0.12)	530 (0.10)
Fluid intake reduced	8 (0.04)	4 (0.02)	8 (0.02)	0	24 (0.03)	12 (0.00)	64 (0.01)
Fluid retention	9 (0.05)	19 (0.07)	37 (0.08)	0	48 (0.06)	102 (0.03)	220 (0.04)
Flushing	4 (0.02)	96 (0.38)	111 (0.23)	0	267 (0.31)	968 (0.29)	1465 (0.28)
Foaming at mouth	10 (0.05)	8 (0.03)	1 (0.00)	0	11 (0.01)	10 (0.00)	55 (0.01)
Foetal death	21 (0.12)	6 (0.02)	3 (0.01)	9 (1.96)	45 (0.05)	59 (0.02)	147 (0.03)
Foetal exposure during pregnancy	16 (0.09)	4 (0.02)	3 (0.01)	15 (3.26)	10 (0.01)	24 (0.01)	80 (0.02)
Foetal growth restriction	12 (0.07)	3 (0.01)	2 (0.00)	10 (2.17)	3 (0.00)	25 (0.01)	58 (0.01)
Foetal hypokinesia	8 (0.04)	3 (0.01)	0	3 (0.65)	9 (0.01)	26 (0.01)	52 (0.01)
Food allergy	0	23 (0.09)	16 (0.03)	1 (0.22)	9 (0.01)	62 (0.02)	113 (0.02)
Food aversion	0	2 (0.01)	11 (0.02)	0	7 (0.01)	52 (0.02)	72 (0.01)
Food refusal	11 (0.06)	2 (0.01)	6 (0.01)	0	4 (0.00)	38 (0.01)	62 (0.01)
Foreign body sensation in eyes	1 (0.01)	0	3 (0.01)	0	2 (0.00)	45 (0.01)	51 (0.01)
Formication	0	6 (0.02)	38 (0.08)	1 (0.22)	20 (0.02)	180 (0.05)	248 (0.05)
Fracture	2 (0.01)	2 (0.01)	3 (0.01)	0	29 (0.03)	26 (0.01)	66 (0.01)
Freezing phenomenon	0	2 (0.01)	11 (0.02)	0	5 (0.01)	119 (0.04)	137 (0.03)
Frequent bowel movements	1 (0.01)	2 (0.01)	9 (0.02)	0	13 (0.02)	62 (0.02)	88 (0.02)
Full blood count	3 (0.02)	51 (0.20)	13 (0.03)	0	46 (0.05)	53 (0.02)	167 (0.03)
Full blood count abnormal	2 (0.01)	16 (0.06)	6 (0.01)	1 (0.22)	23 (0.03)	20 (0.01)	70 (0.01)
Furuncle	1 (0.01)	3 (0.01)	5 (0.01)	0	7 (0.01)	56 (0.02)	72 (0.01)
Gait disturbance	41 (0.22)	203 (0.80)	812 (1.66)	1 (0.22)	936 (1.09)	1116 (0.33)	3249 (0.63)
Gait inability	33 (0.18)	95 (0.37)	370 (0.76)	1 (0.22)	344 (0.40)	337 (0.10)	1246 (0.24)
Gamma-glutamyltransferase increased	0	2 (0.01)	4 (0.01)	0	18 (0.02)	27 (0.01)	56 (0.01)
Gastric disorder	2 (0.01)	3 (0.01)	7 (0.01)	0	10 (0.01)	33 (0.01)	56 (0.01)
Gastric haemorrhage	12 (0.07)	6 (0.02)	3 (0.01)	0	17 (0.02)	16 (0.00)	59 (0.01)
Gastric ulcer	1 (0.01)	3 (0.01)	1 (0.00)	0	21 (0.02)	42 (0.01)	73 (0.01)
Gastritis	3 (0.02)	6 (0.02)	48 (0.10)	0	60 (0.07)	126 (0.04)	248 (0.05)
Gastroenteritis	3 (0.02)	8 (0.03)	8 (0.02)	0	76 (0.09)	58 (0.02)	159 (0.03)
Gastroenteritis viral	2 (0.01)	1 (0.00)	8 (0.02)	0	8 (0.01)	75 (0.02)	95 (0.02)
Gastrointestinal disorder	8 (0.04)	13 (0.05)	63 (0.13)	0	81 (0.09)	154 (0.05)	326 (0.06)
Gastrointestinal haemorrhage	65 (0.36)	50 (0.20)	9 (0.02)	0	87 (0.10)	56 (0.02)	285 (0.06)
Gastrointestinal inflammation	3 (0.02)	5 (0.02)	5 (0.01)	0	22 (0.03)	16 (0.00)	53 (0.01)
Gastrointestinal pain	0	9 (0.04)	95 (0.19)	0	81 (0.09)	351 (0.10)	543 (0.11)
Gastrointestinal sounds abnormal	0	1 (0.00)	10 (0.02)	0	7 (0.01)	35 (0.01)	53 (0.01)
Gastrooesophageal reflux disease	4 (0.02)	21 (0.08)	84 (0.17)	0	63 (0.07)	256 (0.08)	432 (0.08)
Gaze palsy	6 (0.03)	16 (0.06)	7 (0.01)	0	31 (0.04)	97 (0.03)	167 (0.03)
General physical health deterioration	334 (1.83)	78 (0.31)	74 (0.15)	0	350 (0.41)	110 (0.03)	1035 (0.20)
Generalised oedema	9 (0.05)	12 (0.05)	6 (0.01)	0	36 (0.04)	41 (0.01)	110 (0.02)
Generalised tonic-clonic seizure	16 (0.09)	81 (0.32)	24 (0.05)	0	247 (0.29)	332 (0.10)	716 (0.14)
Genital haemorrhage	0	2 (0.01)	3 (0.01)	0	9 (0.01)	89 (0.03)	104 (0.02)
Genital herpes	0	0	27 (0.06)	0	13 (0.02)	122 (0.04)	162 (0.03)
Giant cell arteritis	4 (0.02)	19 (0.07)	28 (0.06)	0	90 (0.10)	84 (0.02)	229 (0.04)
Gingival bleeding	0	36 (0.14)	27 (0.06)	0	59 (0.07)	161 (0.05)	288 (0.06)
Gingival pain	0	3 (0.01)	37 (0.08)	1 (0.22)	9 (0.01)	215 (0.06)	268 (0.05)
Gingival swelling	0	3 (0.01)	12 (0.02)	0	8 (0.01)	61 (0.02)	85 (0.02)
Glaucoma	1 (0.01)	0	14 (0.03)	0	15 (0.02)	49 (0.01)	83 (0.02)
Glomerulonephritis minimal lesion	0	3 (0.01)	2 (0.00)	0	26 (0.03)	23 (0.01)	54 (0.01)
Glossitis	0	4 (0.02)	4 (0.01)	0	6 (0.01)	47 (0.01)	62 (0.01)
Glossodynia	0	5 (0.02)	43 (0.09)	0	15 (0.02)	251 (0.07)	315 (0.06)
Goitre	0	2 (0.01)	13 (0.03)	0	18 (0.02)	39 (0.01)	73 (0.01)
Gout	1 (0.01)	4 (0.02)	60 (0.12)	0	46 (0.05)	191 (0.06)	304 (0.06)
Grip strength decreased	2 (0.01)	4 (0.02)	67 (0.14)	0	30 (0.03)	86 (0.03)	190 (0.04)
Groin pain	6 (0.03)	16 (0.06)	86 (0.18)	0	53 (0.06)	253 (0.08)	426 (0.08)
Guillain-Barre syndrome	38 (0.21)	375 (1.48)	358 (0.73)	1 (0.22)	1352 (1.57)	534 (0.16)	2725 (0.53)
Haematemesis	63 (0.35)	40 (0.16)	18 (0.04)	0	92 (0.11)	180 (0.05)	419 (0.08)
Haematochezia	9 (0.05)	18 (0.07)	31 (0.06)	1 (0.22)	128 (0.15)	536 (0.16)	739 (0.14)
Haematocrit decreased	5 (0.03)	2 (0.01)	0	0	31 (0.04)	17 (0.01)	58 (0.01)
Haematoma	23 (0.13)	85 (0.34)	86 (0.18)	2 (0.43)	228 (0.27)	395 (0.12)	842 (0.16)
Haematuria	10 (0.05)	30 (0.12)	20 (0.04)	0	116 (0.14)	200 (0.06)	396 (0.08)
Haemoglobin decreased	21 (0.12)	39 (0.15)	12 (0.02)	1 (0.22)	113 (0.13)	56 (0.02)	262 (0.05)
Haemolysis	5 (0.03)	14 (0.06)	1 (0.00)	0	24 (0.03)	27 (0.01)	73 (0.01)
Haemolytic anaemia	5 (0.03)	21 (0.08)	3 (0.01)	0	44 (0.05)	27 (0.01)	106 (0.02)
Haemophagocytic lymphohistiocytosis	16 (0.09)	36 (0.14)	0	0	34 (0.04)	8 (0.00)	103 (0.02)
Haemoptysis	39 (0.21)	94 (0.37)	25 (0.05)	0	137 (0.16)	156 (0.05)	476 (0.09)
Haemorrhage	73 (0.40)	177 (0.70)	147 (0.30)	13 (2.83)	277 (0.32)	2299 (0.68)	3045 (0.59)
Haemorrhage in pregnancy	0	4 (0.02)	0	2 (0.43)	10 (0.01)	38 (0.01)	54 (0.01)
Haemorrhage intracranial	67 (0.37)	50 (0.20)	10 (0.02)	0	36 (0.04)	17 (0.01)	195 (0.04)
Haemorrhage subcutaneous	3 (0.02)	1 (0.00)	4 (0.01)	0	19 (0.02)	185 (0.06)	224 (0.04)
Haemorrhage urinary tract	2 (0.01)	12 (0.05)	7 (0.01)	0	19 (0.02)	122 (0.04)	165 (0.03)
Haemorrhagic diathesis	2 (0.01)	7 (0.03)	1 (0.00)	0	11 (0.01)	33 (0.01)	60 (0.01)
Haemorrhagic stroke	117 (0.64)	72 (0.28)	16 (0.03)	0	69 (0.08)	28 (0.01)	311 (0.06)
Haemorrhagic transformation stroke	17 (0.09)	13 (0.05)	2 (0.00)	0	16 (0.02)	0	51 (0.01)
Haemorrhoids	2 (0.01)	2 (0.01)	16 (0.03)	0	15 (0.02)	88 (0.03)	124 (0.02)
Haemorrhoids thrombosed	0	2 (0.01)	6 (0.01)	0	14 (0.02)	59 (0.02)	81 (0.02)
Hallucination	12 (0.07)	49 (0.19)	204 (0.42)	0	143 (0.17)	1366 (0.41)	1810 (0.35)
Hallucination, auditory	0	7 (0.03)	10 (0.02)	0	20 (0.02)	111 (0.03)	153 (0.03)
Hallucination, visual	2 (0.01)	8 (0.03)	15 (0.03)	0	25 (0.03)	169 (0.05)	223 (0.04)
Hangover	0	0	41 (0.08)	0	6 (0.01)	181 (0.05)	229 (0.04)
Head banging	0	2 (0.01)	34 (0.07)	0	8 (0.01)	34 (0.01)	79 (0.02)
Head discomfort	3 (0.02)	59 (0.23)	312 (0.64)	0	246 (0.29)	914 (0.27)	1560 (0.30)
Head injury	18 (0.10)	54 (0.21)	27 (0.06)	0	143 (0.17)	165 (0.05)	433 (0.08)
Headache	482 (2.64)	2197 (8.67)	16082 (32.90)	31 (6.74)	9308 (10.84)	76999 (22.91)	105704 (20.53)
Heart rate	0	24 (0.09)	84 (0.17)	0	83 (0.10)	803 (0.24)	994 (0.19)
Heart rate abnormal	3 (0.02)	19 (0.07)	30 (0.06)	0	58 (0.07)	150 (0.04)	264 (0.05)
Heart rate decreased	12 (0.07)	62 (0.24)	40 (0.08)	1 (0.22)	137 (0.16)	336 (0.10)	610 (0.12)
Heart rate increased	35 (0.19)	320 (1.26)	565 (1.16)	5 (1.09)	921 (1.07)	2945 (0.88)	4889 (0.95)
Heart rate irregular	6 (0.03)	52 (0.21)	109 (0.22)	3 (0.65)	153 (0.18)	404 (0.12)	738 (0.14)
Heavy menstrual bleeding	0	68 (0.27)	625 (1.28)	3 (0.65)	284 (0.33)	6426 (1.91)	7424 (1.44)
Hemianaesthesia	1 (0.01)	7 (0.03)	22 (0.05)	0	57 (0.07)	73 (0.02)	162 (0.03)
Hemianopia	1 (0.01)	10 (0.04)	9 (0.02)	0	26 (0.03)	14 (0.00)	69 (0.01)
Hemiparaesthesia	2 (0.01)	5 (0.02)	16 (0.03)	0	56 (0.07)	161 (0.05)	245 (0.05)
Hemiparesis	82 (0.45)	201 (0.79)	188 (0.38)	0	543 (0.63)	428 (0.13)	1545 (0.30)
Hemiplegia	35 (0.19)	98 (0.39)	106 (0.22)	0	208 (0.24)	174 (0.05)	707 (0.14)
Hemiplegic migraine	0	5 (0.02)	29 (0.06)	0	19 (0.02)	41 (0.01)	95 (0.02)
Henoch-Schonlein purpura	1 (0.01)	2 (0.01)	9 (0.02)	0	52 (0.06)	34 (0.01)	99 (0.02)
Heparin-induced thrombocytopenia	5 (0.03)	24 (0.09)	2 (0.00)	0	11 (0.01)	7 (0.00)	52 (0.01)
Heparin-induced thrombocytopenia test positive	9 (0.05)	13 (0.05)	0	0	38 (0.04)	3 (0.00)	69 (0.01)
Hepatic cirrhosis	10 (0.05)	7 (0.03)	3 (0.01)	0	21 (0.02)	10 (0.00)	59 (0.01)
Hepatic cytolysis	2 (0.01)	4 (0.02)	0	0	58 (0.07)	49 (0.01)	114 (0.02)
Hepatic enzyme increased	4 (0.02)	14 (0.06)	6 (0.01)	0	63 (0.07)	47 (0.01)	141 (0.03)
Hepatic failure	39 (0.21)	23 (0.09)	2 (0.00)	0	24 (0.03)	9 (0.00)	114 (0.02)
Hepatic function abnormal	7 (0.04)	13 (0.05)	6 (0.01)	0	91 (0.11)	46 (0.01)	173 (0.03)
Hepatic pain	1 (0.01)	6 (0.02)	30 (0.06)	0	12 (0.01)	76 (0.02)	126 (0.02)
Hepatic steatosis	6 (0.03)	5 (0.02)	6 (0.01)	0	28 (0.03)	12 (0.00)	60 (0.01)
Hepatic vein thrombosis	8 (0.04)	12 (0.05)	2 (0.00)	0	27 (0.03)	9 (0.00)	63 (0.01)
Hepatitis	6 (0.03)	11 (0.04)	6 (0.01)	0	77 (0.09)	96 (0.03)	202 (0.04)
Hepatitis acute	6 (0.03)	7 (0.03)	1 (0.00)	0	55 (0.06)	29 (0.01)	98 (0.02)
Herpes ophthalmic	0	1 (0.00)	5 (0.01)	0	11 (0.01)	92 (0.03)	110 (0.02)
Herpes simplex	0	4 (0.02)	13 (0.03)	0	17 (0.02)	78 (0.02)	112 (0.02)
Herpes virus infection	0	2 (0.01)	13 (0.03)	0	17 (0.02)	61 (0.02)	93 (0.02)
Herpes zoster	19 (0.10)	58 (0.23)	452 (0.92)	0	700 (0.82)	3718 (1.11)	4970 (0.97)
Herpes zoster oticus	1 (0.01)	3 (0.01)	24 (0.05)	0	42 (0.05)	80 (0.02)	152 (0.03)
Hiatus hernia	4 (0.02)	8 (0.03)	3 (0.01)	0	33 (0.04)	11 (0.00)	59 (0.01)
Hiccups	2 (0.01)	6 (0.02)	8 (0.02)	0	12 (0.01)	51 (0.02)	79 (0.02)
Hip fracture	8 (0.04)	2 (0.01)	6 (0.01)	0	28 (0.03)	18 (0.01)	68 (0.01)
Hordeolum	0	2 (0.01)	7 (0.01)	0	4 (0.00)	44 (0.01)	58 (0.01)
Hormone level abnormal	0	2 (0.01)	23 (0.05)	0	7 (0.01)	103 (0.03)	136 (0.03)
Hospitalisation	14 (0.08)	9 (0.04)	3 (0.01)	0	346 (0.40)	1 (0.00)	411 (0.08)
Hot flush	4 (0.02)	37 (0.15)	337 (0.69)	1 (0.22)	199 (0.23)	2253 (0.67)	2848 (0.55)
Hunger	1 (0.01)	2 (0.01)	7 (0.01)	0	4 (0.00)	81 (0.02)	96 (0.02)
Hydrocephalus	15 (0.08)	20 (0.08)	2 (0.00)	0	17 (0.02)	9 (0.00)	69 (0.01)
Hyperacusis	0	12 (0.05)	134 (0.27)	0	49 (0.06)	162 (0.05)	359 (0.07)
Hyperaesthesia	1 (0.01)	7 (0.03)	96 (0.20)	1 (0.22)	45 (0.05)	332 (0.10)	486 (0.09)
Hyperaesthesia teeth	0	3 (0.01)	6 (0.01)	0	3 (0.00)	55 (0.02)	67 (0.01)
Hypercoagulation	5 (0.03)	16 (0.06)	3 (0.01)	0	21 (0.02)	20 (0.01)	67 (0.01)
Hyperglycaemia	14 (0.08)	37 (0.15)	25 (0.05)	0	92 (0.11)	204 (0.06)	386 (0.07)
Hyperhidrosis	70 (0.38)	336 (1.33)	1520 (3.11)	3 (0.65)	1005 (1.17)	9033 (2.69)	12058 (2.34)
Hyperkalaemia	26 (0.14)	9 (0.04)	1 (0.00)	0	39 (0.05)	13 (0.00)	101 (0.02)
Hyperpyrexia	39 (0.21)	34 (0.13)	25 (0.05)	0	128 (0.15)	1485 (0.44)	1720 (0.33)
Hypersensitivity	20 (0.11)	421 (1.66)	341 (0.70)	2 (0.43)	1013 (1.18)	2735 (0.81)	4600 (0.89)
Hypersomnia	8 (0.04)	37 (0.15)	117 (0.24)	1 (0.22)	66 (0.08)	402 (0.12)	647 (0.13)
Hypertension	121 (0.66)	552 (2.18)	428 (0.88)	5 (1.09)	1824 (2.12)	3621 (1.08)	6718 (1.30)
Hypertensive crisis	13 (0.07)	73 (0.29)	12 (0.02)	0	292 (0.34)	580 (0.17)	987 (0.19)
Hypertensive emergency	2 (0.01)	12 (0.05)	0	0	29 (0.03)	23 (0.01)	68 (0.01)
Hypertensive urgency	0	6 (0.02)	2 (0.00)	0	14 (0.02)	36 (0.01)	59 (0.01)
Hyperthermia	11 (0.06)	10 (0.04)	21 (0.04)	0	46 (0.05)	104 (0.03)	195 (0.04)
Hyperthyroidism	1 (0.01)	16 (0.06)	33 (0.07)	1 (0.22)	44 (0.05)	221 (0.07)	320 (0.06)
Hyperventilation	7 (0.04)	27 (0.11)	26 (0.05)	0	198 (0.23)	256 (0.08)	529 (0.10)
Hypervolaemia	5 (0.03)	9 (0.04)	1 (0.00)	0	40 (0.05)	8 (0.00)	71 (0.01)
Hypoacusis	2 (0.01)	18 (0.07)	265 (0.54)	0	100 (0.12)	466 (0.14)	860 (0.17)
Hypoaesthesia	38 (0.21)	570 (2.25)	2089 (4.27)	2 (0.43)	2375 (2.77)	6493 (1.93)	11739 (2.28)
Hypoaesthesia eye	0	2 (0.01)	10 (0.02)	0	9 (0.01)	35 (0.01)	57 (0.01)
Hypoaesthesia oral	4 (0.02)	86 (0.34)	142 (0.29)	1 (0.22)	264 (0.31)	854 (0.25)	1378 (0.27)
Hypogeusia	1 (0.01)	1 (0.00)	28 (0.06)	0	9 (0.01)	17 (0.01)	58 (0.01)
Hypoglycaemia	18 (0.10)	40 (0.16)	20 (0.04)	1 (0.22)	70 (0.08)	198 (0.06)	353 (0.07)
Hypokalaemia	16 (0.09)	27 (0.11)	7 (0.01)	0	91 (0.11)	49 (0.01)	219 (0.04)
Hypokinesia	8 (0.04)	19 (0.07)	102 (0.21)	1 (0.22)	101 (0.12)	246 (0.07)	506 (0.10)
Hypomenorrhoea	0	1 (0.00)	48 (0.10)	1 (0.22)	7 (0.01)	379 (0.11)	436 (0.08)
Hyponatraemia	15 (0.08)	42 (0.17)	12 (0.02)	0	129 (0.15)	9 (0.00)	227 (0.04)
Hypophagia	41 (0.22)	15 (0.06)	13 (0.03)	0	110 (0.13)	53 (0.02)	252 (0.05)
Hypopnoea	14 (0.08)	41 (0.16)	49 (0.10)	0	35 (0.04)	249 (0.07)	404 (0.08)
Hyporeflexia	1 (0.01)	12 (0.05)	13 (0.03)	0	32 (0.04)	18 (0.01)	80 (0.02)
Hyporesponsive to stimuli	15 (0.08)	6 (0.02)	2 (0.00)	0	23 (0.03)	12 (0.00)	62 (0.01)
Hypotension	214 (1.17)	346 (1.37)	223 (0.46)	0	822 (0.96)	1388 (0.41)	3135 (0.61)
Hypothermia	18 (0.10)	23 (0.09)	19 (0.04)	0	31 (0.04)	226 (0.07)	333 (0.06)
Hypothyroidism	1 (0.01)	4 (0.02)	29 (0.06)	0	30 (0.03)	155 (0.05)	234 (0.05)
Hypotonia	10 (0.05)	22 (0.09)	37 (0.08)	0	174 (0.20)	98 (0.03)	348 (0.07)
Hypotonic-hyporesponsive episode	7 (0.04)	2 (0.01)	0	0	11 (0.01)	50 (0.01)	71 (0.01)
Hypovolaemic shock	15 (0.08)	9 (0.04)	0	0	13 (0.02)	122 (0.04)	166 (0.03)
Hypoxia	175 (0.96)	147 (0.58)	14 (0.03)	0	487 (0.57)	161 (0.05)	1086 (0.21)
IIIrd nerve paralysis	0	2 (0.01)	11 (0.02)	0	34 (0.04)	39 (0.01)	90 (0.02)
IgA nephropathy	0	1 (0.00)	8 (0.02)	0	16 (0.02)	34 (0.01)	60 (0.01)
Ileus	7 (0.04)	5 (0.02)	2 (0.00)	0	28 (0.03)	5 (0.00)	55 (0.01)
Illness	56 (0.31)	121 (0.48)	694 (1.42)	4 (0.87)	417 (0.49)	4758 (1.42)	6096 (1.18)
Immediate post-injection reaction	5 (0.03)	37 (0.15)	54 (0.11)	0	40 (0.05)	15 (0.00)	151 (0.03)
Immobile	7 (0.04)	11 (0.04)	48 (0.10)	0	22 (0.03)	100 (0.03)	198 (0.04)
Immune system disorder	4 (0.02)	6 (0.02)	38 (0.08)	0	34 (0.04)	97 (0.03)	191 (0.04)
Immune thrombocytopenia	56 (0.31)	334 (1.32)	16 (0.03)	0	670 (0.78)	366 (0.11)	1490 (0.29)
Immunisation	33 (0.18)	52 (0.21)	183 (0.37)	0	135 (0.16)	2215 (0.66)	2631 (0.51)
Immunisation reaction	0	1 (0.00)	6 (0.01)	0	32 (0.04)	117 (0.03)	165 (0.03)
Immunodeficiency	0	1 (0.00)	7 (0.01)	0	16 (0.02)	61 (0.02)	96 (0.02)
Immunoglobulin therapy	2 (0.01)	28 (0.11)	19 (0.04)	0	50 (0.06)	1 (0.00)	101 (0.02)
Impaired driving ability	3 (0.02)	27 (0.11)	101 (0.21)	0	39 (0.05)	62 (0.02)	242 (0.05)
Impaired quality of life	0	4 (0.02)	43 (0.09)	0	11 (0.01)	45 (0.01)	110 (0.02)
Impaired work ability	5 (0.03)	84 (0.33)	479 (0.98)	2 (0.43)	169 (0.20)	440 (0.13)	1231 (0.24)
Inappropriate schedule of product administration	10 (0.05)	8 (0.03)	48 (0.10)	3 (0.65)	56 (0.07)	322 (0.10)	464 (0.09)
Incoherent	6 (0.03)	7 (0.03)	8 (0.02)	0	38 (0.04)	33 (0.01)	98 (0.02)
Incontinence	10 (0.05)	20 (0.08)	45 (0.09)	0	54 (0.06)	73 (0.02)	216 (0.04)
Incorrect route of product administration	6 (0.03)	7 (0.03)	14 (0.03)	0	31 (0.04)	69 (0.02)	136 (0.03)
Increased appetite	0	1 (0.00)	12 (0.02)	0	3 (0.00)	49 (0.01)	66 (0.01)
Increased tendency to bruise	1 (0.01)	12 (0.05)	34 (0.07)	0	20 (0.02)	104 (0.03)	173 (0.03)
Induration	1 (0.01)	6 (0.02)	13 (0.03)	0	36 (0.04)	65 (0.02)	123 (0.02)
Infarction	36 (0.20)	48 (0.19)	7 (0.01)	0	63 (0.07)	21 (0.01)	183 (0.04)
Infection	42 (0.23)	51 (0.20)	98 (0.20)	1 (0.22)	247 (0.29)	506 (0.15)	971 (0.19)
Infectious mononucleosis	0	4 (0.02)	31 (0.06)	0	18 (0.02)	61 (0.02)	114 (0.02)
Inflammation	17 (0.09)	98 (0.39)	347 (0.71)	1 (0.22)	377 (0.44)	935 (0.28)	1827 (0.35)
Inflammatory marker increased	5 (0.03)	9 (0.04)	14 (0.03)	0	68 (0.08)	27 (0.01)	136 (0.03)
Inflammatory pain	0	2 (0.01)	16 (0.03)	1 (0.22)	4 (0.00)	33 (0.01)	56 (0.01)
Influenza	6 (0.03)	55 (0.22)	702 (1.44)	0	560 (0.65)	5833 (1.74)	7166 (1.39)
Influenza like illness	58 (0.32)	126 (0.50)	1622 (3.32)	1 (0.22)	1039 (1.21)	10936 (3.25)	13848 (2.69)
Initial insomnia	0	3 (0.01)	11 (0.02)	0	8 (0.01)	84 (0.02)	107 (0.02)
Injected limb mobility decreased	2 (0.01)	10 (0.04)	182 (0.37)	0	11 (0.01)	210 (0.06)	416 (0.08)
Injection related reaction	0	1 (0.00)	42 (0.09)	0	7 (0.01)	480 (0.14)	531 (0.10)
Injection site bruising	1 (0.01)	2 (0.01)	20 (0.04)	0	6 (0.01)	95 (0.03)	125 (0.02)
Injection site erythema	6 (0.03)	22 (0.09)	149 (0.30)	0	141 (0.16)	600 (0.18)	921 (0.18)
Injection site hypoaesthesia	0	1 (0.00)	14 (0.03)	0	16 (0.02)	25 (0.01)	56 (0.01)
Injection site induration	1 (0.01)	4 (0.02)	40 (0.08)	0	20 (0.02)	33 (0.01)	98 (0.02)
Injection site inflammation	5 (0.03)	4 (0.02)	16 (0.03)	0	4 (0.00)	38 (0.01)	67 (0.01)
Injection site mass	1 (0.01)	3 (0.01)	64 (0.13)	0	13 (0.02)	838 (0.25)	919 (0.18)
Injection site movement impairment	0	0	30 (0.06)	0	9 (0.01)	18 (0.01)	57 (0.01)
Injection site oedema	0	1 (0.00)	5 (0.01)	0	4 (0.00)	80 (0.02)	90 (0.02)
Injection site pain	26 (0.14)	77 (0.30)	932 (1.91)	1 (0.22)	617 (0.72)	4139 (1.23)	5812 (1.13)
Injection site paraesthesia	0	7 (0.03)	11 (0.02)	0	9 (0.01)	33 (0.01)	60 (0.01)
Injection site pruritus	3 (0.02)	9 (0.04)	49 (0.10)	0	24 (0.03)	244 (0.07)	330 (0.06)
Injection site rash	0	6 (0.02)	32 (0.07)	1 (0.22)	21 (0.02)	228 (0.07)	288 (0.06)
Injection site reaction	5 (0.03)	26 (0.10)	2903 (5.94)	0	108 (0.13)	282 (0.08)	3331 (0.65)
Injection site swelling	6 (0.03)	24 (0.09)	147 (0.30)	0	160 (0.19)	343 (0.10)	686 (0.13)
Injection site warmth	4 (0.02)	10 (0.04)	71 (0.15)	0	18 (0.02)	272 (0.08)	375 (0.07)
Injury	6 (0.03)	15 (0.06)	20 (0.04)	0	45 (0.05)	49 (0.01)	138 (0.03)
Insomnia	25 (0.14)	141 (0.56)	1062 (2.17)	2 (0.43)	377 (0.44)	3962 (1.18)	5610 (1.09)
Intensive care	33 (0.18)	82 (0.32)	7 (0.01)	0	69 (0.08)	0	196 (0.04)
Interchange of vaccine products	19 (0.10)	28 (0.11)	79 (0.16)	1 (0.22)	79 (0.09)	1200 (0.36)	1411 (0.27)
Intermenstrual bleeding	0	12 (0.05)	113 (0.23)	2 (0.43)	64 (0.07)	1092 (0.32)	1289 (0.25)
Internal haemorrhage	19 (0.10)	17 (0.07)	9 (0.02)	0	27 (0.03)	166 (0.05)	250 (0.05)
International normalised ratio decreased	1 (0.01)	10 (0.04)	3 (0.01)	0	14 (0.02)	36 (0.01)	68 (0.01)
International normalised ratio increased	8 (0.04)	26 (0.10)	10 (0.02)	0	47 (0.05)	99 (0.03)	203 (0.04)
Interstitial lung disease	54 (0.30)	38 (0.15)	17 (0.03)	0	116 (0.14)	58 (0.02)	300 (0.06)
Intervertebral disc protrusion	1 (0.01)	3 (0.01)	18 (0.04)	0	26 (0.03)	24 (0.01)	74 (0.01)
Intestinal haemorrhage	3 (0.02)	6 (0.02)	1 (0.00)	0	27 (0.03)	31 (0.01)	69 (0.01)
Intestinal ischaemia	65 (0.36)	38 (0.15)	4 (0.01)	0	43 (0.05)	17 (0.01)	174 (0.03)
Intestinal obstruction	20 (0.11)	10 (0.04)	3 (0.01)	0	40 (0.05)	28 (0.01)	102 (0.02)
Intracardiac thrombus	31 (0.17)	52 (0.21)	8 (0.02)	0	52 (0.06)	12 (0.00)	165 (0.03)
Intracranial aneurysm	24 (0.13)	25 (0.10)	3 (0.01)	0	25 (0.03)	10 (0.00)	95 (0.02)
Intracranial pressure increased	23 (0.13)	16 (0.06)	11 (0.02)	0	34 (0.04)	48 (0.01)	148 (0.03)
Intraventricular haemorrhage	15 (0.08)	20 (0.08)	2 (0.00)	0	17 (0.02)	2 (0.00)	59 (0.01)
Iridocyclitis	1 (0.01)	0	12 (0.02)	0	11 (0.01)	92 (0.03)	119 (0.02)
Iron deficiency anaemia	2 (0.01)	10 (0.04)	7 (0.01)	0	20 (0.02)	21 (0.01)	63 (0.01)
Irregular breathing	3 (0.02)	4 (0.02)	6 (0.01)	0	3 (0.00)	38 (0.01)	54 (0.01)
Irritability	9 (0.05)	13 (0.05)	56 (0.11)	0	62 (0.07)	414 (0.12)	559 (0.11)
Irritable bowel syndrome	0	5 (0.02)	41 (0.08)	0	21 (0.02)	166 (0.05)	235 (0.05)
Ischaemia	17 (0.09)	39 (0.15)	23 (0.05)	0	70 (0.08)	23 (0.01)	176 (0.03)
Ischaemic cerebral infarction	15 (0.08)	61 (0.24)	13 (0.03)	0	78 (0.09)	14 (0.00)	184 (0.04)
Ischaemic stroke	136 (0.75)	382 (1.51)	177 (0.36)	0	995 (1.16)	147 (0.04)	1854 (0.36)
Jaundice	18 (0.10)	17 (0.07)	6 (0.01)	0	109 (0.13)	67 (0.02)	227 (0.04)
Joint dislocation	0	3 (0.01)	15 (0.03)	0	11 (0.01)	24 (0.01)	58 (0.01)
Joint effusion	2 (0.01)	1 (0.00)	18 (0.04)	0	19 (0.02)	36 (0.01)	77 (0.01)
Joint injury	1 (0.01)	5 (0.02)	22 (0.05)	0	16 (0.02)	23 (0.01)	70 (0.01)
Joint lock	1 (0.01)	1 (0.00)	26 (0.05)	0	10 (0.01)	68 (0.02)	106 (0.02)
Joint noise	0	1 (0.00)	27 (0.06)	0	0	62 (0.02)	90 (0.02)
Joint range of motion decreased	2 (0.01)	10 (0.04)	141 (0.29)	0	31 (0.04)	292 (0.09)	484 (0.09)
Joint stiffness	1 (0.01)	12 (0.05)	189 (0.39)	0	51 (0.06)	528 (0.16)	787 (0.15)
Joint swelling	8 (0.04)	65 (0.26)	428 (0.88)	0	227 (0.26)	1153 (0.34)	1904 (0.37)
Joint warmth	0	0	15 (0.03)	0	4 (0.00)	43 (0.01)	62 (0.01)
Jugular vein thrombosis	9 (0.05)	50 (0.20)	2 (0.00)	0	67 (0.08)	37 (0.01)	169 (0.03)
Kidney infection	2 (0.01)	14 (0.06)	19 (0.04)	0	46 (0.05)	130 (0.04)	217 (0.04)
Laboratory test	11 (0.06)	58 (0.23)	22 (0.05)	0	44 (0.05)	42 (0.01)	177 (0.03)
Laboratory test abnormal	0	7 (0.03)	7 (0.01)	0	26 (0.03)	11 (0.00)	51 (0.01)
Labyrinthitis	1 (0.01)	3 (0.01)	63 (0.13)	0	35 (0.04)	189 (0.06)	292 (0.06)
Lacrimation increased	1 (0.01)	15 (0.06)	73 (0.15)	0	60 (0.07)	335 (0.10)	490 (0.10)
Lactic acidosis	19 (0.10)	11 (0.04)	3 (0.01)	0	36 (0.04)	6 (0.00)	85 (0.02)
Lacunar infarction	4 (0.02)	24 (0.09)	3 (0.01)	0	64 (0.07)	31 (0.01)	133 (0.03)
Lacunar stroke	0	16 (0.06)	10 (0.02)	0	26 (0.03)	16 (0.00)	68 (0.01)
Language disorder	1 (0.01)	11 (0.04)	14 (0.03)	0	102 (0.12)	22 (0.01)	158 (0.03)
Laryngeal oedema	6 (0.03)	77 (0.30)	0	0	76 (0.09)	240 (0.07)	411 (0.08)
Laryngitis	1 (0.01)	2 (0.01)	12 (0.02)	0	10 (0.01)	58 (0.02)	83 (0.02)
Laryngospasm	1 (0.01)	19 (0.07)	3 (0.01)	0	18 (0.02)	43 (0.01)	84 (0.02)
Left ventricular dysfunction	7 (0.04)	28 (0.11)	5 (0.01)	0	44 (0.05)	7 (0.00)	97 (0.02)
Left ventricular failure	15 (0.08)	17 (0.07)	1 (0.00)	0	31 (0.04)	5 (0.00)	73 (0.01)
Lethargy	87 (0.48)	148 (0.58)	647 (1.32)	1 (0.22)	410 (0.48)	4562 (1.36)	5912 (1.15)
Leukocytosis	14 (0.08)	24 (0.09)	2 (0.00)	0	97 (0.11)	13 (0.00)	164 (0.03)
Leukopenia	10 (0.05)	17 (0.07)	7 (0.01)	0	70 (0.08)	92 (0.03)	203 (0.04)
Lichen planus	0	0	12 (0.02)	0	3 (0.00)	36 (0.01)	51 (0.01)
Limb discomfort	11 (0.06)	87 (0.34)	509 (1.04)	0	941 (1.10)	2479 (0.74)	4065 (0.79)
Limb injury	5 (0.03)	9 (0.04)	126 (0.26)	1 (0.22)	30 (0.03)	272 (0.08)	447 (0.09)
Limb mass	0	5 (0.02)	9 (0.02)	0	9 (0.01)	60 (0.02)	86 (0.02)
Lip dry	0	6 (0.02)	7 (0.01)	0	4 (0.00)	74 (0.02)	92 (0.02)
Lip oedema	1 (0.01)	14 (0.06)	12 (0.02)	0	62 (0.07)	205 (0.06)	299 (0.06)
Lip pain	0	1 (0.00)	12 (0.02)	0	8 (0.01)	79 (0.02)	103 (0.02)
Lip pruritus	0	11 (0.04)	4 (0.01)	0	13 (0.02)	61 (0.02)	90 (0.02)
Lip swelling	4 (0.02)	173 (0.68)	96 (0.20)	1 (0.22)	289 (0.34)	1185 (0.35)	1769 (0.34)
Listless	3 (0.02)	3 (0.01)	24 (0.05)	0	7 (0.01)	103 (0.03)	141 (0.03)
Livedo reticularis	9 (0.05)	12 (0.05)	15 (0.03)	0	17 (0.02)	73 (0.02)	132 (0.03)
Liver disorder	8 (0.04)	22 (0.09)	19 (0.04)	0	67 (0.08)	40 (0.01)	164 (0.03)
Liver function test abnormal	6 (0.03)	13 (0.05)	12 (0.02)	0	48 (0.06)	50 (0.01)	142 (0.03)
Liver function test increased	2 (0.01)	10 (0.04)	7 (0.01)	0	22 (0.03)	35 (0.01)	79 (0.02)
Liver injury	2 (0.01)	13 (0.05)	10 (0.02)	0	30 (0.03)	43 (0.01)	106 (0.02)
Local reaction	8 (0.04)	12 (0.05)	62 (0.13)	0	69 (0.08)	107 (0.03)	258 (0.05)
Localised infection	1 (0.01)	4 (0.02)	16 (0.03)	0	27 (0.03)	113 (0.03)	163 (0.03)
Localised oedema	3 (0.02)	25 (0.10)	27 (0.06)	0	39 (0.05)	104 (0.03)	201 (0.04)
Loss of consciousness	324 (1.78)	633 (2.50)	284 (0.58)	2 (0.43)	1466 (1.71)	6429 (1.91)	9528 (1.85)
Loss of control of legs	0	9 (0.04)	16 (0.03)	0	26 (0.03)	81 (0.02)	140 (0.03)
Loss of libido	0	1 (0.00)	22 (0.05)	0	4 (0.00)	29 (0.01)	57 (0.01)
Loss of personal independence in daily activities	7 (0.04)	83 (0.33)	494 (1.01)	0	154 (0.18)	419 (0.12)	1218 (0.24)
Lower respiratory tract infection	35 (0.19)	35 (0.14)	73 (0.15)	0	73 (0.09)	427 (0.13)	662 (0.13)
Lumbar puncture	1 (0.01)	21 (0.08)	31 (0.06)	0	46 (0.05)	7 (0.00)	107 (0.02)
Lung consolidation	8 (0.04)	8 (0.03)	1 (0.00)	0	32 (0.04)	3 (0.00)	64 (0.01)
Lung disorder	40 (0.22)	28 (0.11)	24 (0.05)	0	137 (0.16)	65 (0.02)	310 (0.06)
Lung infiltration	36 (0.20)	28 (0.11)	0	0	138 (0.16)	6 (0.00)	227 (0.04)
Lung neoplasm malignant	21 (0.12)	8 (0.03)	3 (0.01)	0	9 (0.01)	21 (0.01)	68 (0.01)
Lung opacity	22 (0.12)	55 (0.22)	5 (0.01)	0	186 (0.22)	12 (0.00)	295 (0.06)
Lyme disease	0	1 (0.00)	10 (0.02)	0	18 (0.02)	90 (0.03)	125 (0.02)
Lymph node pain	3 (0.02)	10 (0.04)	173 (0.35)	0	63 (0.07)	1529 (0.45)	1787 (0.35)
Lymphadenitis	1 (0.01)	14 (0.06)	33 (0.07)	0	61 (0.07)	251 (0.07)	363 (0.07)
Lymphadenopathy	25 (0.14)	178 (0.70)	1359 (2.78)	10 (2.17)	793 (0.92)	9306 (2.77)	11737 (2.28)
Lymphangitis	0	1 (0.00)	3 (0.01)	0	14 (0.02)	61 (0.02)	79 (0.02)
Lymphocyte count decreased	0	2 (0.01)	2 (0.00)	0	25 (0.03)	19 (0.01)	51 (0.01)
Lymphoedema	1 (0.01)	8 (0.03)	37 (0.08)	0	14 (0.02)	161 (0.05)	224 (0.04)
Lymphoma	13 (0.07)	13 (0.05)	7 (0.01)	0	14 (0.02)	86 (0.03)	138 (0.03)
Lymphopenia	4 (0.02)	17 (0.07)	5 (0.01)	0	44 (0.05)	30 (0.01)	101 (0.02)
Macular oedema	0	0	27 (0.06)	0	7 (0.01)	40 (0.01)	79 (0.02)
Magnetic resonance imaging	1 (0.01)	43 (0.17)	27 (0.06)	1 (0.22)	50 (0.06)	36 (0.01)	158 (0.03)
Magnetic resonance imaging abnormal	1 (0.01)	20 (0.08)	7 (0.01)	0	22 (0.03)	13 (0.00)	64 (0.01)
Magnetic resonance imaging head	1 (0.01)	18 (0.07)	17 (0.03)	0	32 (0.04)	36 (0.01)	104 (0.02)
Magnetic resonance imaging head abnormal	6 (0.03)	45 (0.18)	38 (0.08)	0	79 (0.09)	6 (0.00)	174 (0.03)
Major depression	0	4 (0.02)	11 (0.02)	0	8 (0.01)	40 (0.01)	64 (0.01)
Malaise	636 (3.49)	912 (3.60)	5669 (11.60)	10 (2.17)	3447 (4.01)	14384 (4.28)	25402 (4.93)
Mania	0	6 (0.02)	8 (0.02)	0	15 (0.02)	27 (0.01)	56 (0.01)
Mass	2 (0.01)	9 (0.04)	26 (0.05)	0	18 (0.02)	121 (0.04)	186 (0.04)
Mast cell activation syndrome	0	4 (0.02)	6 (0.01)	0	2 (0.00)	34 (0.01)	51 (0.01)
Mastication disorder	0	7 (0.03)	20 (0.04)	0	16 (0.02)	18 (0.01)	65 (0.01)
Mastitis	0	0	8 (0.02)	0	13 (0.02)	230 (0.07)	251 (0.05)
Maternal exposure during breast feeding	1 (0.01)	13 (0.05)	78 (0.16)	7 (1.52)	25 (0.03)	1040 (0.31)	1167 (0.23)
Maternal exposure during pregnancy	39 (0.21)	53 (0.21)	54 (0.11)	94 (20.43)	159 (0.19)	614 (0.18)	1035 (0.20)
Mechanical ventilation	22 (0.12)	30 (0.12)	4 (0.01)	0	16 (0.02)	0	74 (0.01)
Medication error	6 (0.03)	7 (0.03)	7 (0.01)	0	14 (0.02)	49 (0.01)	84 (0.02)
Melaena	18 (0.10)	16 (0.06)	2 (0.00)	0	48 (0.06)	60 (0.02)	157 (0.03)
Memory impairment	11 (0.06)	62 (0.24)	294 (0.60)	0	245 (0.29)	478 (0.14)	1129 (0.22)
Meniere's disease	1 (0.01)	2 (0.01)	39 (0.08)	0	22 (0.03)	100 (0.03)	166 (0.03)
Meningitis	5 (0.03)	15 (0.06)	9 (0.02)	0	106 (0.12)	54 (0.02)	201 (0.04)
Meningitis aseptic	0	10 (0.04)	0	0	91 (0.11)	23 (0.01)	125 (0.02)
Meningitis viral	1 (0.01)	7 (0.03)	4 (0.01)	0	48 (0.06)	27 (0.01)	88 (0.02)
Menometrorrhagia	0	4 (0.02)	12 (0.02)	0	11 (0.01)	53 (0.02)	81 (0.02)
Menopausal symptoms	0	1 (0.00)	7 (0.01)	0	1 (0.00)	48 (0.01)	57 (0.01)
Menopause	0	2 (0.01)	15 (0.03)	0	2 (0.00)	67 (0.02)	86 (0.02)
Menstrual discomfort	0	0	3 (0.01)	0	10 (0.01)	40 (0.01)	53 (0.01)
Menstrual disorder	1 (0.01)	27 (0.11)	287 (0.59)	6 (1.30)	106 (0.12)	1847 (0.55)	2287 (0.44)
Menstruation delayed	0	14 (0.06)	267 (0.55)	5 (1.09)	36 (0.04)	2647 (0.79)	2972 (0.58)
Menstruation irregular	0	17 (0.07)	289 (0.59)	6 (1.30)	86 (0.10)	2447 (0.73)	2856 (0.55)
Mental disorder	2 (0.01)	13 (0.05)	30 (0.06)	0	51 (0.06)	60 (0.02)	163 (0.03)
Mental fatigue	1 (0.01)	14 (0.06)	152 (0.31)	0	22 (0.03)	459 (0.14)	650 (0.13)
Mental impairment	10 (0.05)	23 (0.09)	89 (0.18)	0	53 (0.06)	473 (0.14)	677 (0.13)
Mental status changes	42 (0.23)	49 (0.19)	10 (0.02)	0	187 (0.22)	3 (0.00)	306 (0.06)
Mesenteric vein thrombosis	21 (0.12)	61 (0.24)	3 (0.01)	0	107 (0.12)	26 (0.01)	228 (0.04)
Metabolic acidosis	24 (0.13)	23 (0.09)	0	0	23 (0.03)	4 (0.00)	80 (0.02)
Metabolic function test	4 (0.02)	26 (0.10)	6 (0.01)	0	25 (0.03)	26 (0.01)	87 (0.02)
Metamorphopsia	0	4 (0.02)	14 (0.03)	0	9 (0.01)	56 (0.02)	84 (0.02)
Micturition urgency	2 (0.01)	2 (0.01)	24 (0.05)	0	29 (0.03)	105 (0.03)	167 (0.03)
Middle insomnia	0	6 (0.02)	26 (0.05)	0	14 (0.02)	123 (0.04)	170 (0.03)
Migraine	11 (0.06)	180 (0.71)	1849 (3.78)	0	679 (0.79)	7710 (2.29)	10473 (2.03)
Migraine with aura	0	4 (0.02)	108 (0.22)	1 (0.22)	56 (0.07)	430 (0.13)	602 (0.12)
Migraine without aura	0	0	7 (0.01)	0	2 (0.00)	47 (0.01)	56 (0.01)
Miliaria	0	3 (0.01)	22 (0.05)	0	6 (0.01)	152 (0.05)	184 (0.04)
Miller Fisher syndrome	2 (0.01)	11 (0.04)	14 (0.03)	0	51 (0.06)	13 (0.00)	94 (0.02)
Mitral valve incompetence	8 (0.04)	13 (0.05)	4 (0.01)	0	45 (0.05)	17 (0.01)	99 (0.02)
Mobility decreased	36 (0.20)	114 (0.45)	496 (1.01)	2 (0.43)	399 (0.46)	442 (0.13)	1545 (0.30)
Monoparesis	4 (0.02)	24 (0.09)	56 (0.11)	0	91 (0.11)	185 (0.06)	372 (0.07)
Monoplegia	8 (0.04)	30 (0.12)	125 (0.26)	0	127 (0.15)	451 (0.13)	765 (0.15)
Mood altered	3 (0.02)	7 (0.03)	23 (0.05)	0	13 (0.02)	113 (0.03)	162 (0.03)
Mood swings	1 (0.01)	6 (0.02)	41 (0.08)	1 (0.22)	9 (0.01)	167 (0.05)	227 (0.04)
Morning sickness	0	0	4 (0.01)	0	4 (0.00)	49 (0.01)	57 (0.01)
Motion sickness	0	3 (0.01)	41 (0.08)	0	7 (0.01)	140 (0.04)	193 (0.04)
Motor dysfunction	12 (0.07)	24 (0.09)	61 (0.12)	0	121 (0.14)	69 (0.02)	298 (0.06)
Mouth haemorrhage	9 (0.05)	31 (0.12)	7 (0.01)	0	47 (0.05)	61 (0.02)	170 (0.03)
Mouth swelling	3 (0.02)	42 (0.17)	21 (0.04)	0	53 (0.06)	179 (0.05)	301 (0.06)
Mouth ulceration	1 (0.01)	8 (0.03)	79 (0.16)	0	27 (0.03)	559 (0.17)	675 (0.13)
Movement disorder	12 (0.07)	43 (0.17)	186 (0.38)	0	288 (0.34)	320 (0.10)	896 (0.17)
Multiple organ dysfunction syndrome	206 (1.13)	32 (0.13)	1 (0.00)	0	19 (0.02)	11 (0.00)	309 (0.06)
Multiple sclerosis	1 (0.01)	7 (0.03)	78 (0.16)	1 (0.22)	88 (0.10)	239 (0.07)	428 (0.08)
Multiple sclerosis relapse	1 (0.01)	5 (0.02)	59 (0.12)	0	84 (0.10)	196 (0.06)	348 (0.07)
Muscle atrophy	2 (0.01)	10 (0.04)	37 (0.08)	0	21 (0.02)	38 (0.01)	112 (0.02)
Muscle contractions involuntary	0	9 (0.04)	60 (0.12)	0	37 (0.04)	79 (0.02)	188 (0.04)
Muscle contracture	0	8 (0.03)	10 (0.02)	0	9 (0.01)	27 (0.01)	60 (0.01)
Muscle disorder	1 (0.01)	4 (0.02)	21 (0.04)	0	18 (0.02)	23 (0.01)	71 (0.01)
Muscle fatigue	1 (0.01)	9 (0.04)	215 (0.44)	0	32 (0.04)	926 (0.28)	1188 (0.23)
Muscle injury	0	5 (0.02)	19 (0.04)	0	7 (0.01)	58 (0.02)	89 (0.02)
Muscle rigidity	7 (0.04)	13 (0.05)	50 (0.10)	0	45 (0.05)	99 (0.03)	218 (0.04)
Muscle rupture	0	1 (0.00)	6 (0.01)	0	3 (0.00)	55 (0.02)	65 (0.01)
Muscle spasms	17 (0.09)	179 (0.71)	945 (1.93)	6 (1.30)	627 (0.73)	3764 (1.12)	5597 (1.09)
Muscle spasticity	2 (0.01)	4 (0.02)	26 (0.05)	0	24 (0.03)	38 (0.01)	94 (0.02)
Muscle strain	0	9 (0.04)	21 (0.04)	0	19 (0.02)	76 (0.02)	125 (0.02)
Muscle swelling	0	0	13 (0.03)	0	11 (0.01)	58 (0.02)	83 (0.02)
Muscle tightness	2 (0.01)	29 (0.11)	90 (0.18)	2 (0.43)	95 (0.11)	295 (0.09)	523 (0.10)
Muscle twitching	5 (0.03)	39 (0.15)	232 (0.47)	1 (0.22)	173 (0.20)	598 (0.18)	1060 (0.21)
Muscular weakness	61 (0.33)	275 (1.08)	1410 (2.88)	2 (0.43)	1335 (1.55)	2531 (0.75)	5748 (1.12)
Musculoskeletal chest pain	3 (0.02)	45 (0.18)	121 (0.25)	0	115 (0.13)	542 (0.16)	838 (0.16)
Musculoskeletal discomfort	2 (0.01)	13 (0.05)	58 (0.12)	0	62 (0.07)	206 (0.06)	351 (0.07)
Musculoskeletal disorder	2 (0.01)	12 (0.05)	60 (0.12)	0	35 (0.04)	53 (0.02)	170 (0.03)
Musculoskeletal pain	5 (0.03)	26 (0.10)	122 (0.25)	1 (0.22)	176 (0.20)	564 (0.17)	905 (0.18)
Musculoskeletal stiffness	11 (0.06)	65 (0.26)	872 (1.78)	0	320 (0.37)	2604 (0.77)	3907 (0.76)
Myalgia	146 (0.80)	645 (2.54)	10050 (20.56)	12 (2.61)	2792 (3.25)	28560 (8.50)	42400 (8.24)
Myasthenia gravis	3 (0.02)	11 (0.04)	35 (0.07)	0	64 (0.07)	78 (0.02)	195 (0.04)
Mydriasis	9 (0.05)	11 (0.04)	9 (0.02)	0	33 (0.04)	52 (0.02)	124 (0.02)
Myelitis	4 (0.02)	9 (0.04)	50 (0.10)	1 (0.22)	188 (0.22)	51 (0.02)	308 (0.06)
Myelitis transverse	1 (0.01)	24 (0.09)	129 (0.26)	0	148 (0.17)	77 (0.02)	387 (0.08)
Myocardial infarction	738 (4.05)	869 (3.43)	75 (0.15)	0	914 (1.06)	507 (0.15)	3211 (0.62)
Myocardial injury	1 (0.01)	18 (0.07)	5 (0.01)	0	28 (0.03)	22 (0.01)	79 (0.02)
Myocardial ischaemia	95 (0.52)	12 (0.05)	3 (0.01)	0	49 (0.06)	21 (0.01)	194 (0.04)
Myocardial necrosis marker increased	1 (0.01)	10 (0.04)	1 (0.00)	0	43 (0.05)	13 (0.00)	80 (0.02)
Myocardial strain imaging	5 (0.03)	35 (0.14)	0	0	25 (0.03)	1 (0.00)	75 (0.01)
Myocarditis	110 (0.60)	771 (3.04)	196 (0.40)	3 (0.65)	3992 (4.65)	2352 (0.70)	7543 (1.47)
Myoclonus	3 (0.02)	11 (0.04)	26 (0.05)	0	55 (0.06)	74 (0.02)	175 (0.03)
Myopathy	2 (0.01)	3 (0.01)	13 (0.03)	0	15 (0.02)	17 (0.01)	53 (0.01)
Myositis	5 (0.03)	16 (0.06)	48 (0.10)	0	82 (0.10)	85 (0.03)	241 (0.05)
Narcolepsy	0	2 (0.01)	18 (0.04)	0	4 (0.00)	52 (0.02)	80 (0.02)
Nasal congestion	7 (0.04)	24 (0.09)	146 (0.30)	0	100 (0.12)	680 (0.20)	961 (0.19)
Nasal discomfort	0	4 (0.02)	20 (0.04)	0	14 (0.02)	116 (0.03)	154 (0.03)
Nasal dryness	0	5 (0.02)	13 (0.03)	0	4 (0.00)	47 (0.01)	69 (0.01)
Nasal oedema	0	5 (0.02)	3 (0.01)	0	9 (0.01)	35 (0.01)	53 (0.01)
Nasopharyngitis	57 (0.31)	37 (0.15)	276 (0.56)	1 (0.22)	319 (0.37)	1930 (0.57)	2638 (0.51)
Nausea	309 (1.69)	1036 (4.09)	8213 (16.80)	13 (2.83)	4762 (5.55)	36339 (10.81)	51014 (9.91)
Near death experience	0	31 (0.12)	3 (0.01)	0	14 (0.02)	100 (0.03)	169 (0.03)
Neck mass	3 (0.02)	4 (0.02)	7 (0.01)	0	13 (0.02)	51 (0.02)	78 (0.02)
Neck pain	18 (0.10)	159 (0.63)	957 (1.96)	2 (0.43)	627 (0.73)	3743 (1.11)	5555 (1.08)
Neoplasm malignant	16 (0.09)	9 (0.04)	5 (0.01)	0	17 (0.02)	90 (0.03)	150 (0.03)
Nephritis	1 (0.01)	3 (0.01)	0	0	25 (0.03)	42 (0.01)	72 (0.01)
Nephrolithiasis	1 (0.01)	9 (0.04)	7 (0.01)	0	61 (0.07)	127 (0.04)	215 (0.04)
Nephrotic syndrome	2 (0.01)	10 (0.04)	6 (0.01)	0	121 (0.14)	69 (0.02)	210 (0.04)
Nerve compression	1 (0.01)	3 (0.01)	26 (0.05)	0	7 (0.01)	69 (0.02)	108 (0.02)
Nerve injury	1 (0.01)	18 (0.07)	149 (0.30)	0	41 (0.05)	165 (0.05)	385 (0.07)
Nervous system disorder	28 (0.15)	37 (0.15)	156 (0.32)	1 (0.22)	150 (0.17)	137 (0.04)	534 (0.10)
Nervousness	3 (0.02)	20 (0.08)	117 (0.24)	0	50 (0.06)	595 (0.18)	792 (0.15)
Neuralgia	4 (0.02)	50 (0.20)	599 (1.23)	1 (0.22)	332 (0.39)	1441 (0.43)	2451 (0.48)
Neuralgic amyotrophy	1 (0.01)	2 (0.01)	65 (0.13)	0	44 (0.05)	69 (0.02)	183 (0.04)
Neuritis	0	2 (0.01)	21 (0.04)	0	57 (0.07)	45 (0.01)	129 (0.03)
Neurological symptom	14 (0.08)	48 (0.19)	112 (0.23)	0	145 (0.17)	136 (0.04)	467 (0.09)
Neuromyelitis optica spectrum disorder	1 (0.01)	4 (0.02)	14 (0.03)	0	31 (0.04)	8 (0.00)	63 (0.01)
Neuropathy peripheral	0	23 (0.09)	251 (0.51)	0	153 (0.18)	1237 (0.37)	1709 (0.33)
Neutropenia	2 (0.01)	30 (0.12)	4 (0.01)	0	59 (0.07)	140 (0.04)	243 (0.05)
Night sweats	5 (0.03)	39 (0.15)	249 (0.51)	1 (0.22)	145 (0.17)	1704 (0.51)	2153 (0.42)
Nightmare	2 (0.01)	12 (0.05)	76 (0.16)	1 (0.22)	20 (0.02)	409 (0.12)	523 (0.10)
Nipple pain	1 (0.01)	0	5 (0.01)	0	3 (0.00)	52 (0.02)	61 (0.01)
Nodule	3 (0.02)	13 (0.05)	30 (0.06)	0	46 (0.05)	92 (0.03)	188 (0.04)
Non-cardiac chest pain	0	1 (0.00)	8 (0.02)	0	10 (0.01)	51 (0.02)	72 (0.01)
Noninfective encephalitis	2 (0.01)	7 (0.03)	9 (0.02)	1 (0.22)	12 (0.01)	26 (0.01)	63 (0.01)
Nuchal rigidity	1 (0.01)	3 (0.01)	19 (0.04)	0	19 (0.02)	63 (0.02)	105 (0.02)
Nystagmus	1 (0.01)	10 (0.04)	23 (0.05)	0	69 (0.08)	39 (0.01)	152 (0.03)
Obstructive airways disorder	5 (0.03)	40 (0.16)	2 (0.00)	0	35 (0.04)	37 (0.01)	123 (0.02)
Occipital neuralgia	0	2 (0.01)	19 (0.04)	0	4 (0.00)	39 (0.01)	64 (0.01)
Ocular discomfort	2 (0.01)	9 (0.04)	50 (0.10)	1 (0.22)	72 (0.08)	141 (0.04)	276 (0.05)
Ocular hyperaemia	2 (0.01)	26 (0.10)	59 (0.12)	1 (0.22)	94 (0.11)	492 (0.15)	689 (0.13)
Odynophagia	1 (0.01)	9 (0.04)	20 (0.04)	1 (0.22)	44 (0.05)	174 (0.05)	254 (0.05)
Oedema	28 (0.15)	54 (0.21)	57 (0.12)	1 (0.22)	242 (0.28)	344 (0.10)	754 (0.15)
Oedema peripheral	49 (0.27)	117 (0.46)	170 (0.35)	0	372 (0.43)	630 (0.19)	1385 (0.27)
Off label use	27 (0.15)	47 (0.19)	153 (0.31)	1 (0.22)	132 (0.15)	1994 (0.59)	2379 (0.46)
Oligomenorrhoea	0	3 (0.01)	51 (0.10)	0	13 (0.02)	178 (0.05)	245 (0.05)
Ophthalmic herpes zoster	0	3 (0.01)	26 (0.05)	0	67 (0.08)	319 (0.09)	420 (0.08)
Ophthalmic migraine	0	0	14 (0.03)	0	15 (0.02)	49 (0.01)	79 (0.02)
Ophthalmic vein thrombosis	2 (0.01)	7 (0.03)	14 (0.03)	0	40 (0.05)	64 (0.02)	129 (0.03)
Ophthalmoplegia	0	3 (0.01)	12 (0.02)	0	28 (0.03)	25 (0.01)	72 (0.01)
Optic ischaemic neuropathy	0	1 (0.00)	47 (0.10)	0	43 (0.05)	49 (0.01)	144 (0.03)
Optic neuritis	0	3 (0.01)	95 (0.19)	0	155 (0.18)	149 (0.04)	410 (0.08)
Oral blood blister	0	10 (0.04)	4 (0.01)	0	13 (0.02)	25 (0.01)	54 (0.01)
Oral candidiasis	5 (0.03)	3 (0.01)	7 (0.01)	0	11 (0.01)	55 (0.02)	83 (0.02)
Oral discomfort	1 (0.01)	15 (0.06)	34 (0.07)	0	34 (0.04)	169 (0.05)	253 (0.05)
Oral disorder	1 (0.01)	3 (0.01)	5 (0.01)	0	18 (0.02)	33 (0.01)	62 (0.01)
Oral herpes	1 (0.01)	11 (0.04)	78 (0.16)	0	31 (0.04)	621 (0.18)	745 (0.14)
Oral mucosal blistering	0	5 (0.02)	18 (0.04)	0	21 (0.02)	45 (0.01)	91 (0.02)
Oral pain	2 (0.01)	9 (0.04)	55 (0.11)	1 (0.22)	27 (0.03)	303 (0.09)	405 (0.08)
Oral pruritus	0	13 (0.05)	8 (0.02)	0	33 (0.04)	71 (0.02)	128 (0.02)
Organising pneumonia	4 (0.02)	4 (0.02)	3 (0.01)	0	29 (0.03)	13 (0.00)	55 (0.01)
Oropharyngeal blistering	0	1 (0.00)	1 (0.00)	0	5 (0.01)	61 (0.02)	70 (0.01)
Oropharyngeal discomfort	1 (0.01)	34 (0.13)	24 (0.05)	0	260 (0.30)	560 (0.17)	903 (0.18)
Oropharyngeal pain	41 (0.22)	131 (0.52)	760 (1.55)	2 (0.43)	569 (0.66)	4724 (1.41)	6259 (1.22)
Orthopnoea	3 (0.02)	12 (0.05)	4 (0.01)	0	32 (0.04)	20 (0.01)	73 (0.01)
Orthostatic hypotension	1 (0.01)	9 (0.04)	29 (0.06)	0	43 (0.05)	70 (0.02)	160 (0.03)
Osteoarthritis	1 (0.01)	3 (0.01)	68 (0.14)	0	28 (0.03)	109 (0.03)	214 (0.04)
Ovarian cyst	1 (0.01)	4 (0.02)	16 (0.03)	0	24 (0.03)	38 (0.01)	84 (0.02)
Overdose	3 (0.02)	2 (0.01)	9 (0.02)	0	16 (0.02)	68 (0.02)	101 (0.02)
Ovulation pain	0	0	8 (0.02)	0	2 (0.00)	80 (0.02)	91 (0.02)
Oxygen saturation decreased	199 (1.09)	166 (0.65)	63 (0.13)	0	562 (0.65)	643 (0.19)	1774 (0.34)
Pain	182 (1.00)	675 (2.66)	4258 (8.71)	12 (2.61)	2480 (2.89)	18929 (5.63)	26772 (5.20)
Pain in extremity	139 (0.76)	877 (3.46)	4883 (9.99)	12 (2.61)	2550 (2.97)	23676 (7.04)	32377 (6.29)
Pain in jaw	5 (0.03)	39 (0.15)	164 (0.34)	0	127 (0.15)	687 (0.20)	1039 (0.20)
Pain of skin	2 (0.01)	14 (0.06)	206 (0.42)	0	49 (0.06)	907 (0.27)	1184 (0.23)
Painful respiration	5 (0.03)	30 (0.12)	29 (0.06)	0	94 (0.11)	87 (0.03)	254 (0.05)
Palatal oedema	0	13 (0.05)	2 (0.00)	0	16 (0.02)	68 (0.02)	100 (0.02)
Pallor	39 (0.21)	123 (0.49)	101 (0.21)	1 (0.22)	268 (0.31)	785 (0.23)	1368 (0.27)
Palpitations	32 (0.18)	541 (2.13)	1464 (3.00)	4 (0.87)	2117 (2.47)	7010 (2.09)	11277 (2.19)
Pancreatitis	10 (0.05)	33 (0.13)	11 (0.02)	0	166 (0.19)	104 (0.03)	331 (0.06)
Pancreatitis acute	9 (0.05)	38 (0.15)	2 (0.00)	0	241 (0.28)	56 (0.02)	356 (0.07)
Pancytopenia	16 (0.09)	34 (0.13)	3 (0.01)	0	83 (0.10)	26 (0.01)	179 (0.03)
Panic attack	3 (0.02)	36 (0.14)	124 (0.25)	0	138 (0.16)	411 (0.12)	731 (0.14)
Panic reaction	1 (0.01)	10 (0.04)	22 (0.05)	0	16 (0.02)	74 (0.02)	125 (0.02)
Papilloedema	1 (0.01)	5 (0.02)	25 (0.05)	0	30 (0.03)	36 (0.01)	102 (0.02)
Papule	0	1 (0.00)	14 (0.03)	1 (0.22)	13 (0.02)	123 (0.04)	154 (0.03)
Paraesthesia	22 (0.12)	536 (2.11)	2149 (4.40)	2 (0.43)	2930 (3.41)	9838 (2.93)	15648 (3.04)
Paraesthesia oral	1 (0.01)	113 (0.45)	149 (0.30)	0	308 (0.36)	1275 (0.38)	1861 (0.36)
Paralysis	28 (0.15)	116 (0.46)	237 (0.48)	1 (0.22)	324 (0.38)	715 (0.21)	1500 (0.29)
Paranasal sinus discomfort	2 (0.01)	3 (0.01)	21 (0.04)	0	9 (0.01)	86 (0.03)	122 (0.02)
Paranoia	3 (0.02)	8 (0.03)	13 (0.03)	0	21 (0.02)	44 (0.01)	90 (0.02)
Paraparesis	1 (0.01)	4 (0.02)	14 (0.03)	0	44 (0.05)	23 (0.01)	91 (0.02)
Paraplegia	0	9 (0.04)	16 (0.03)	0	24 (0.03)	16 (0.00)	70 (0.01)
Paresis	4 (0.02)	15 (0.06)	36 (0.07)	0	98 (0.11)	58 (0.02)	226 (0.04)
Parkinson's disease	6 (0.03)	3 (0.01)	10 (0.02)	0	16 (0.02)	64 (0.02)	104 (0.02)
Parosmia	1 (0.01)	12 (0.05)	149 (0.30)	0	43 (0.05)	336 (0.10)	542 (0.11)
Partial seizures	7 (0.04)	17 (0.07)	10 (0.02)	0	51 (0.06)	92 (0.03)	185 (0.04)
Pelvic pain	2 (0.01)	11 (0.04)	73 (0.15)	1 (0.22)	36 (0.04)	242 (0.07)	367 (0.07)
Pelvic venous thrombosis	4 (0.02)	35 (0.14)	5 (0.01)	0	55 (0.06)	25 (0.01)	131 (0.03)
Pemphigoid	7 (0.04)	9 (0.04)	23 (0.05)	0	50 (0.06)	115 (0.03)	208 (0.04)
Pemphigus	0	3 (0.01)	5 (0.01)	0	11 (0.01)	36 (0.01)	56 (0.01)
Periarthritis	0	1 (0.00)	242 (0.50)	0	16 (0.02)	414 (0.12)	675 (0.13)
Pericardial effusion	30 (0.16)	133 (0.52)	28 (0.06)	0	416 (0.48)	330 (0.10)	999 (0.19)
Pericarditis	17 (0.09)	316 (1.25)	149 (0.30)	0	1875 (2.18)	3097 (0.92)	5514 (1.07)
Periorbital oedema	0	3 (0.01)	4 (0.01)	0	19 (0.02)	54 (0.02)	82 (0.02)
Periorbital swelling	0	11 (0.04)	30 (0.06)	0	46 (0.05)	193 (0.06)	280 (0.05)
Peripheral artery occlusion	4 (0.02)	12 (0.05)	2 (0.00)	0	33 (0.04)	6 (0.00)	60 (0.01)
Peripheral artery thrombosis	13 (0.07)	60 (0.24)	11 (0.02)	0	97 (0.11)	45 (0.01)	232 (0.05)
Peripheral circulatory failure	5 (0.03)	3 (0.01)	1 (0.00)	0	33 (0.04)	14 (0.00)	61 (0.01)
Peripheral coldness	21 (0.12)	68 (0.27)	241 (0.49)	0	173 (0.20)	1216 (0.36)	1742 (0.34)
Peripheral embolism	4 (0.02)	19 (0.07)	9 (0.02)	0	40 (0.05)	20 (0.01)	95 (0.02)
Peripheral ischaemia	28 (0.15)	31 (0.12)	9 (0.02)	0	73 (0.09)	28 (0.01)	176 (0.03)
Peripheral sensory neuropathy	0	1 (0.00)	17 (0.03)	0	17 (0.02)	35 (0.01)	70 (0.01)
Peripheral swelling	59 (0.32)	447 (1.76)	1222 (2.50)	5 (1.09)	906 (1.06)	5991 (1.78)	8733 (1.70)
Peripheral vascular disorder	8 (0.04)	14 (0.06)	7 (0.01)	0	57 (0.07)	21 (0.01)	111 (0.02)
Peripheral venous disease	1 (0.01)	10 (0.04)	14 (0.03)	0	13 (0.02)	31 (0.01)	71 (0.01)
Peritonitis	6 (0.03)	14 (0.06)	2 (0.00)	0	28 (0.03)	7 (0.00)	60 (0.01)
Peroneal nerve palsy	1 (0.01)	5 (0.02)	35 (0.07)	0	19 (0.02)	23 (0.01)	85 (0.02)
Persistent postural-perceptual dizziness	0	0	14 (0.03)	0	5 (0.01)	34 (0.01)	53 (0.01)
Petechiae	23 (0.13)	138 (0.54)	56 (0.11)	0	441 (0.51)	450 (0.13)	1151 (0.22)
Petit mal epilepsy	1 (0.01)	12 (0.05)	9 (0.02)	0	26 (0.03)	106 (0.03)	157 (0.03)
Pharyngeal hypoaesthesia	0	8 (0.03)	13 (0.03)	0	22 (0.03)	69 (0.02)	117 (0.02)
Pharyngeal oedema	1 (0.01)	35 (0.14)	10 (0.02)	0	58 (0.07)	104 (0.03)	212 (0.04)
Pharyngeal paraesthesia	0	17 (0.07)	7 (0.01)	0	43 (0.05)	97 (0.03)	167 (0.03)
Pharyngeal swelling	4 (0.02)	257 (1.01)	91 (0.19)	0	242 (0.28)	639 (0.19)	1261 (0.24)
Pharyngitis	0	8 (0.03)	16 (0.03)	0	32 (0.04)	79 (0.02)	137 (0.03)
Phlebitis	0	17 (0.07)	21 (0.04)	0	70 (0.08)	222 (0.07)	333 (0.06)
Phlebitis superficial	0	3 (0.01)	2 (0.00)	0	8 (0.01)	51 (0.02)	65 (0.01)
Photophobia	8 (0.04)	54 (0.21)	392 (0.80)	0	219 (0.26)	1124 (0.33)	1812 (0.35)
Photopsia	2 (0.01)	20 (0.08)	69 (0.14)	0	59 (0.07)	346 (0.10)	501 (0.10)
Photosensitivity reaction	0	9 (0.04)	66 (0.14)	0	29 (0.03)	182 (0.05)	289 (0.06)
Physical deconditioning	6 (0.03)	3 (0.01)	3 (0.01)	0	63 (0.07)	39 (0.01)	128 (0.02)
Piloerection	0	2 (0.01)	12 (0.02)	0	7 (0.01)	102 (0.03)	124 (0.02)
Pityriasis rosea	0	2 (0.01)	6 (0.01)	0	4 (0.00)	86 (0.03)	98 (0.02)
Platelet count decreased	72 (0.39)	219 (0.86)	41 (0.08)	3 (0.65)	362 (0.42)	376 (0.11)	1132 (0.22)
Platelet count increased	3 (0.02)	11 (0.04)	8 (0.02)	1 (0.22)	22 (0.03)	38 (0.01)	87 (0.02)
Platelet count normal	4 (0.02)	21 (0.08)	4 (0.01)	0	35 (0.04)	21 (0.01)	85 (0.02)
Pleural effusion	54 (0.30)	125 (0.49)	23 (0.05)	1 (0.22)	363 (0.42)	74 (0.02)	719 (0.14)
Pleurisy	1 (0.01)	16 (0.06)	24 (0.05)	0	153 (0.18)	68 (0.02)	270 (0.05)
Pleuritic pain	1 (0.01)	45 (0.18)	15 (0.03)	0	80 (0.09)	31 (0.01)	179 (0.03)
Pleuropericarditis	0	6 (0.02)	0	0	36 (0.04)	8 (0.00)	51 (0.01)
Pneumonia	541 (2.97)	380 (1.50)	70 (0.14)	0	1318 (1.54)	737 (0.22)	3272 (0.64)
Pneumonia aspiration	137 (0.75)	31 (0.12)	5 (0.01)	0	61 (0.07)	19 (0.01)	282 (0.05)
Pneumonia bacterial	29 (0.16)	6 (0.02)	2 (0.00)	0	44 (0.05)	17 (0.01)	105 (0.02)
Pneumonia viral	12 (0.07)	4 (0.02)	3 (0.01)	0	24 (0.03)	20 (0.01)	66 (0.01)
Pneumonitis	31 (0.17)	40 (0.16)	11 (0.02)	0	115 (0.13)	60 (0.02)	272 (0.05)
Pneumothorax	13 (0.07)	21 (0.08)	4 (0.01)	0	75 (0.09)	37 (0.01)	168 (0.03)
Pollakiuria	9 (0.05)	17 (0.07)	66 (0.14)	0	54 (0.06)	288 (0.09)	443 (0.09)
Polyarthritis	0	1 (0.00)	29 (0.06)	0	46 (0.05)	118 (0.04)	195 (0.04)
Polymenorrhoea	0	5 (0.02)	111 (0.23)	2 (0.43)	37 (0.04)	702 (0.21)	857 (0.17)
Polymyalgia rheumatica	0	8 (0.03)	129 (0.26)	0	82 (0.10)	417 (0.12)	643 (0.12)
Polyneuropathy	3 (0.02)	15 (0.06)	42 (0.09)	0	119 (0.14)	130 (0.04)	327 (0.06)
Polyuria	5 (0.03)	14 (0.06)	12 (0.02)	0	34 (0.04)	37 (0.01)	104 (0.02)
Poor peripheral circulation	3 (0.02)	10 (0.04)	18 (0.04)	0	21 (0.02)	58 (0.02)	118 (0.02)
Poor quality sleep	5 (0.03)	7 (0.03)	125 (0.26)	0	24 (0.03)	627 (0.19)	791 (0.15)
Portal vein thrombosis	51 (0.28)	95 (0.37)	4 (0.01)	0	199 (0.23)	48 (0.01)	423 (0.08)
Post herpetic neuralgia	0	0	25 (0.05)	0	14 (0.02)	50 (0.01)	91 (0.02)
Post viral fatigue syndrome	0	0	98 (0.20)	0	5 (0.01)	129 (0.04)	234 (0.05)
Post-acute COVID-19 syndrome	0	5 (0.02)	15 (0.03)	0	15 (0.02)	27 (0.01)	67 (0.01)
Postmenopausal haemorrhage	0	5 (0.02)	31 (0.06)	0	33 (0.04)	1038 (0.31)	1108 (0.22)
Postural orthostatic tachycardia syndrome	0	4 (0.02)	45 (0.09)	0	33 (0.04)	46 (0.01)	134 (0.03)
Pregnancy	0	1 (0.00)	4 (0.01)	3 (0.65)	5 (0.01)	41 (0.01)	54 (0.01)
Premature baby	6 (0.03)	8 (0.03)	2 (0.00)	3 (0.65)	33 (0.04)	14 (0.00)	74 (0.01)
Premature labour	0	3 (0.01)	0	1 (0.22)	44 (0.05)	13 (0.00)	62 (0.01)
Premenstrual pain	0	0	22 (0.05)	0	1 (0.00)	148 (0.04)	171 (0.03)
Premenstrual syndrome	0	2 (0.01)	25 (0.05)	0	4 (0.00)	180 (0.05)	213 (0.04)
Presyncope	13 (0.07)	121 (0.48)	239 (0.49)	1 (0.22)	625 (0.73)	1779 (0.53)	2833 (0.55)
Product administered at inappropriate site	0	2 (0.01)	46 (0.09)	0	8 (0.01)	32 (0.01)	88 (0.02)
Product use issue	3 (0.02)	1 (0.00)	11 (0.02)	1 (0.22)	13 (0.02)	215 (0.06)	249 (0.05)
Productive cough	37 (0.20)	31 (0.12)	75 (0.15)	0	180 (0.21)	288 (0.09)	630 (0.12)
Proteinuria	0	5 (0.02)	7 (0.01)	0	40 (0.05)	35 (0.01)	88 (0.02)
Pruritus	15 (0.08)	342 (1.35)	862 (1.76)	4 (0.87)	1159 (1.35)	8329 (2.48)	10807 (2.10)
Psoriasis	2 (0.01)	10 (0.04)	66 (0.14)	0	45 (0.05)	298 (0.09)	423 (0.08)
Psoriatic arthropathy	0	0	27 (0.06)	0	3 (0.00)	103 (0.03)	135 (0.03)
Psychomotor hyperactivity	6 (0.03)	8 (0.03)	10 (0.02)	0	16 (0.02)	48 (0.01)	90 (0.02)
Psychotic disorder	0	17 (0.07)	21 (0.04)	0	53 (0.06)	49 (0.01)	143 (0.03)
Pulmonary artery thrombosis	13 (0.07)	18 (0.07)	0	0	18 (0.02)	1 (0.00)	55 (0.01)
Pulmonary congestion	20 (0.11)	11 (0.04)	9 (0.02)	0	47 (0.05)	163 (0.05)	272 (0.05)
Pulmonary embolism	787 (4.32)	3346 (13.20)	147 (0.30)	0	5202 (6.06)	1997 (0.59)	11683 (2.27)
Pulmonary fibrosis	14 (0.08)	10 (0.04)	10 (0.02)	0	33 (0.04)	35 (0.01)	111 (0.02)
Pulmonary haemorrhage	15 (0.08)	16 (0.06)	1 (0.00)	0	19 (0.02)	5 (0.00)	62 (0.01)
Pulmonary hypertension	12 (0.07)	18 (0.07)	2 (0.00)	0	37 (0.04)	22 (0.01)	108 (0.02)
Pulmonary infarction	12 (0.07)	92 (0.36)	4 (0.01)	0	111 (0.13)	36 (0.01)	274 (0.05)
Pulmonary mass	11 (0.06)	17 (0.07)	9 (0.02)	0	47 (0.05)	13 (0.00)	107 (0.02)
Pulmonary oedema	126 (0.69)	104 (0.41)	16 (0.03)	1 (0.22)	173 (0.20)	80 (0.02)	565 (0.11)
Pulmonary pain	1 (0.01)	37 (0.15)	97 (0.20)	0	72 (0.08)	260 (0.08)	472 (0.09)
Pulmonary thrombosis	43 (0.24)	223 (0.88)	16 (0.03)	0	279 (0.32)	90 (0.03)	677 (0.13)
Pulse abnormal	5 (0.03)	17 (0.07)	8 (0.02)	0	36 (0.04)	63 (0.02)	134 (0.03)
Pulse absent	39 (0.21)	17 (0.07)	0	0	15 (0.02)	15 (0.00)	91 (0.02)
Pulseless electrical activity	54 (0.30)	19 (0.07)	0	0	6 (0.01)	0	91 (0.02)
Puncture site pain	0	0	2 (0.00)	0	2 (0.00)	52 (0.02)	57 (0.01)
Pupils unequal	8 (0.04)	3 (0.01)	8 (0.02)	0	15 (0.02)	18 (0.01)	58 (0.01)
Purpura	12 (0.07)	27 (0.11)	22 (0.05)	0	144 (0.17)	197 (0.06)	412 (0.08)
Pustule	0	4 (0.02)	9 (0.02)	0	16 (0.02)	27 (0.01)	59 (0.01)
Pyelonephritis	6 (0.03)	6 (0.02)	4 (0.01)	0	66 (0.08)	45 (0.01)	134 (0.03)
Pyrexia	1063 (5.83)	1887 (7.44)	12389 (25.35)	31 (6.74)	8875 (10.34)	56015 (16.67)	80904 (15.71)
Q fever	0	3 (0.01)	14 (0.03)	0	3 (0.00)	97 (0.03)	117 (0.02)
Quadriparesis	5 (0.03)	15 (0.06)	10 (0.02)	0	41 (0.05)	2 (0.00)	77 (0.01)
Radiculitis brachial	0	0	30 (0.06)	0	8 (0.01)	20 (0.01)	58 (0.01)
Radiculopathy	0	4 (0.02)	15 (0.03)	0	51 (0.06)	19 (0.01)	91 (0.02)
Rales	20 (0.11)	4 (0.02)	4 (0.01)	0	24 (0.03)	21 (0.01)	81 (0.02)
Rash	38 (0.21)	420 (1.66)	986 (2.02)	5 (1.09)	1880 (2.19)	8420 (2.51)	11854 (2.30)
Rash erythematous	4 (0.02)	55 (0.22)	162 (0.33)	0	192 (0.22)	1705 (0.51)	2130 (0.41)
Rash macular	5 (0.03)	38 (0.15)	105 (0.21)	0	100 (0.12)	749 (0.22)	1005 (0.20)
Rash maculo-papular	0	12 (0.05)	7 (0.01)	0	75 (0.09)	166 (0.05)	264 (0.05)
Rash morbilliform	0	2 (0.01)	7 (0.01)	0	11 (0.01)	57 (0.02)	82 (0.02)
Rash papular	1 (0.01)	12 (0.05)	36 (0.07)	0	49 (0.06)	454 (0.14)	558 (0.11)
Rash pruritic	4 (0.02)	38 (0.15)	128 (0.26)	0	177 (0.21)	1718 (0.51)	2081 (0.40)
Rash vesicular	0	7 (0.03)	22 (0.05)	0	38 (0.04)	142 (0.04)	212 (0.04)
Raynaud's phenomenon	1 (0.01)	2 (0.01)	26 (0.05)	0	15 (0.02)	172 (0.05)	218 (0.04)
Rectal haemorrhage	17 (0.09)	21 (0.08)	15 (0.03)	1 (0.22)	116 (0.14)	318 (0.09)	503 (0.10)
Red blood cell count decreased	8 (0.04)	9 (0.04)	4 (0.01)	1 (0.22)	27 (0.03)	15 (0.00)	68 (0.01)
Red blood cell sedimentation rate increased	2 (0.01)	3 (0.01)	20 (0.04)	0	43 (0.05)	41 (0.01)	114 (0.02)
Renal colic	1 (0.01)	1 (0.00)	5 (0.01)	0	33 (0.04)	31 (0.01)	71 (0.01)
Renal disorder	15 (0.08)	19 (0.07)	23 (0.05)	0	59 (0.07)	31 (0.01)	159 (0.03)
Renal failure	155 (0.85)	108 (0.43)	17 (0.03)	0	154 (0.18)	75 (0.02)	576 (0.11)
Renal impairment	30 (0.16)	28 (0.11)	20 (0.04)	0	82 (0.10)	126 (0.04)	320 (0.06)
Renal infarct	12 (0.07)	24 (0.09)	9 (0.02)	0	55 (0.06)	13 (0.00)	123 (0.02)
Renal pain	4 (0.02)	26 (0.10)	196 (0.40)	1 (0.22)	106 (0.12)	902 (0.27)	1239 (0.24)
Renal vein thrombosis	5 (0.03)	16 (0.06)	3 (0.01)	0	19 (0.02)	5 (0.00)	51 (0.01)
Respiration abnormal	18 (0.10)	25 (0.10)	17 (0.03)	0	73 (0.09)	129 (0.04)	275 (0.05)
Respiratory arrest	210 (1.15)	81 (0.32)	3 (0.01)	0	44 (0.05)	64 (0.02)	452 (0.09)
Respiratory disorder	55 (0.30)	65 (0.26)	197 (0.40)	0	135 (0.16)	143 (0.04)	616 (0.12)
Respiratory distress	112 (0.61)	113 (0.45)	31 (0.06)	1 (0.22)	496 (0.58)	1140 (0.34)	2005 (0.39)
Respiratory failure	329 (1.80)	152 (0.60)	9 (0.02)	0	246 (0.29)	58 (0.02)	857 (0.17)
Respiratory rate decreased	5 (0.03)	7 (0.03)	5 (0.01)	0	10 (0.01)	34 (0.01)	66 (0.01)
Respiratory rate increased	15 (0.08)	26 (0.10)	19 (0.04)	0	56 (0.07)	139 (0.04)	265 (0.05)
Respiratory symptom	5 (0.03)	12 (0.05)	11 (0.02)	0	32 (0.04)	53 (0.02)	116 (0.02)
Respiratory tract congestion	16 (0.09)	8 (0.03)	17 (0.03)	0	88 (0.10)	28 (0.01)	165 (0.03)
Respiratory tract infection	11 (0.06)	5 (0.02)	2 (0.00)	0	22 (0.03)	56 (0.02)	108 (0.02)
Respiratory tract oedema	0	18 (0.07)	1 (0.00)	0	12 (0.01)	35 (0.01)	71 (0.01)
Restless legs syndrome	0	9 (0.04)	78 (0.16)	0	20 (0.02)	346 (0.10)	455 (0.09)
Restlessness	25 (0.14)	25 (0.10)	86 (0.18)	0	142 (0.17)	542 (0.16)	835 (0.16)
Resuscitation	56 (0.31)	32 (0.13)	0	0	18 (0.02)	2 (0.00)	112 (0.02)
Retching	8 (0.04)	31 (0.12)	71 (0.15)	0	100 (0.12)	321 (0.10)	543 (0.11)
Retinal artery occlusion	0	2 (0.01)	99 (0.20)	0	55 (0.06)	92 (0.03)	253 (0.05)
Retinal detachment	0	1 (0.00)	39 (0.08)	0	98 (0.11)	85 (0.03)	228 (0.04)
Retinal haemorrhage	0	2 (0.01)	22 (0.05)	0	13 (0.02)	81 (0.02)	121 (0.02)
Retinal migraine	0	0	10 (0.02)	0	5 (0.01)	85 (0.03)	100 (0.02)
Retinal tear	0	1 (0.00)	12 (0.02)	0	17 (0.02)	44 (0.01)	78 (0.02)
Retinal vascular thrombosis	2 (0.01)	2 (0.01)	37 (0.08)	0	19 (0.02)	30 (0.01)	91 (0.02)
Retinal vein occlusion	0	7 (0.03)	151 (0.31)	0	47 (0.05)	315 (0.09)	524 (0.10)
Retinal vein thrombosis	1 (0.01)	3 (0.01)	48 (0.10)	0	9 (0.01)	90 (0.03)	153 (0.03)
Rhabdomyolysis	13 (0.07)	46 (0.18)	17 (0.03)	0	178 (0.21)	74 (0.02)	337 (0.07)
Rheumatic disorder	0	3 (0.01)	19 (0.04)	0	19 (0.02)	45 (0.01)	90 (0.02)
Rheumatoid arthritis	7 (0.04)	9 (0.04)	199 (0.41)	0	70 (0.08)	768 (0.23)	1069 (0.21)
Rhinalgia	0	1 (0.00)	16 (0.03)	0	2 (0.00)	43 (0.01)	63 (0.01)
Rhinitis	6 (0.03)	10 (0.04)	34 (0.07)	0	38 (0.04)	122 (0.04)	212 (0.04)
Rhinorrhoea	16 (0.09)	37 (0.15)	237 (0.48)	0	202 (0.24)	1747 (0.52)	2253 (0.44)
Rib fracture	7 (0.04)	7 (0.03)	4 (0.01)	0	26 (0.03)	21 (0.01)	75 (0.01)
Road traffic accident	11 (0.06)	12 (0.05)	3 (0.01)	0	44 (0.05)	27 (0.01)	104 (0.02)
Rosacea	0	1 (0.00)	9 (0.02)	0	4 (0.00)	41 (0.01)	55 (0.01)
Rotator cuff syndrome	0	1 (0.00)	57 (0.12)	0	11 (0.01)	111 (0.03)	181 (0.04)
SARS-CoV-2 antibody test negative	1 (0.01)	3 (0.01)	4 (0.01)	0	4 (0.00)	41 (0.01)	54 (0.01)
SARS-CoV-2 test	5 (0.03)	16 (0.06)	5 (0.01)	0	25 (0.03)	23 (0.01)	74 (0.01)
SARS-CoV-2 test negative	12 (0.07)	29 (0.11)	57 (0.12)	0	74 (0.09)	38 (0.01)	212 (0.04)
SARS-CoV-2 test positive	150 (0.82)	40 (0.16)	17 (0.03)	0	398 (0.46)	603 (0.18)	1247 (0.24)
Salivary hypersecretion	3 (0.02)	11 (0.04)	23 (0.05)	0	28 (0.03)	93 (0.03)	160 (0.03)
Sarcoidosis	2 (0.01)	6 (0.02)	18 (0.04)	0	31 (0.04)	66 (0.02)	127 (0.02)
Scab	0	1 (0.00)	15 (0.03)	0	3 (0.00)	35 (0.01)	57 (0.01)
Scar	0	3 (0.01)	23 (0.05)	0	10 (0.01)	51 (0.02)	88 (0.02)
Sciatica	0	5 (0.02)	127 (0.26)	0	35 (0.04)	245 (0.07)	418 (0.08)
Scleritis	0	0	9 (0.02)	0	10 (0.01)	44 (0.01)	63 (0.01)
Screaming	1 (0.01)	1 (0.00)	18 (0.04)	0	9 (0.01)	33 (0.01)	63 (0.01)
Seasonal allergy	1 (0.01)	2 (0.01)	22 (0.05)	0	5 (0.01)	146 (0.04)	176 (0.03)
Secretion discharge	9 (0.05)	11 (0.04)	16 (0.03)	0	18 (0.02)	46 (0.01)	102 (0.02)
Seizure	154 (0.84)	508 (2.00)	335 (0.69)	3 (0.65)	1503 (1.75)	3719 (1.11)	6411 (1.25)
Seizure like phenomena	9 (0.05)	8 (0.03)	6 (0.01)	0	28 (0.03)	97 (0.03)	152 (0.03)
Sensation of foreign body	1 (0.01)	55 (0.22)	25 (0.05)	0	143 (0.17)	235 (0.07)	469 (0.09)
Sense of oppression	3 (0.02)	4 (0.02)	26 (0.05)	1 (0.22)	26 (0.03)	42 (0.01)	105 (0.02)
Sensitive skin	0	6 (0.02)	99 (0.20)	0	120 (0.14)	758 (0.23)	989 (0.19)
Sensory disturbance	0	28 (0.11)	141 (0.29)	0	362 (0.42)	319 (0.09)	874 (0.17)
Sensory loss	2 (0.01)	45 (0.18)	145 (0.30)	0	135 (0.16)	205 (0.06)	548 (0.11)
Sepsis	254 (1.39)	139 (0.55)	24 (0.05)	0	338 (0.39)	99 (0.03)	919 (0.18)
Septic shock	147 (0.81)	42 (0.17)	0	0	48 (0.06)	7 (0.00)	258 (0.05)
Severe acute respiratory syndrome	9 (0.05)	1 (0.00)	0	0	39 (0.05)	17 (0.01)	67 (0.01)
Shock	69 (0.38)	65 (0.26)	15 (0.03)	0	64 (0.07)	187 (0.06)	445 (0.09)
Shoulder injury related to vaccine administration	0	0	78 (0.16)	0	3 (0.00)	90 (0.03)	171 (0.03)
Sinus bradycardia	1 (0.01)	9 (0.04)	6 (0.01)	0	28 (0.03)	19 (0.01)	68 (0.01)
Sinus congestion	0	7 (0.03)	24 (0.05)	0	14 (0.02)	125 (0.04)	173 (0.03)
Sinus disorder	1 (0.01)	4 (0.02)	9 (0.02)	0	3 (0.00)	40 (0.01)	58 (0.01)
Sinus headache	0	3 (0.01)	102 (0.21)	0	14 (0.02)	844 (0.25)	964 (0.19)
Sinus pain	0	12 (0.05)	94 (0.19)	1 (0.22)	16 (0.02)	586 (0.17)	712 (0.14)
Sinus tachycardia	9 (0.05)	36 (0.14)	32 (0.07)	0	167 (0.19)	149 (0.04)	402 (0.08)
Sinusitis	5 (0.03)	11 (0.04)	91 (0.19)	0	63 (0.07)	414 (0.12)	591 (0.11)
Sjogren's syndrome	0	4 (0.02)	10 (0.02)	0	9 (0.01)	54 (0.02)	82 (0.02)
Skin burning sensation	1 (0.01)	31 (0.12)	126 (0.26)	0	85 (0.10)	566 (0.17)	816 (0.16)
Skin discolouration	15 (0.08)	54 (0.21)	65 (0.13)	1 (0.22)	116 (0.14)	311 (0.09)	586 (0.11)
Skin disorder	5 (0.03)	22 (0.09)	387 (0.79)	0	62 (0.07)	150 (0.04)	635 (0.12)
Skin erosion	0	1 (0.00)	12 (0.02)	0	6 (0.01)	51 (0.02)	70 (0.01)
Skin exfoliation	3 (0.02)	10 (0.04)	50 (0.10)	1 (0.22)	42 (0.05)	210 (0.06)	322 (0.06)
Skin haemorrhage	4 (0.02)	9 (0.04)	15 (0.03)	0	32 (0.04)	52 (0.02)	120 (0.02)
Skin infection	1 (0.01)	4 (0.02)	12 (0.02)	0	12 (0.01)	49 (0.01)	80 (0.02)
Skin irritation	0	5 (0.02)	26 (0.05)	0	9 (0.01)	154 (0.05)	194 (0.04)
Skin laceration	0	9 (0.04)	11 (0.02)	0	38 (0.04)	32 (0.01)	98 (0.02)
Skin lesion	4 (0.02)	9 (0.04)	23 (0.05)	0	31 (0.04)	89 (0.03)	161 (0.03)
Skin mass	0	0	8 (0.02)	0	11 (0.01)	70 (0.02)	90 (0.02)
Skin odour abnormal	0	3 (0.01)	11 (0.02)	0	1 (0.00)	38 (0.01)	54 (0.01)
Skin reaction	2 (0.01)	16 (0.06)	36 (0.07)	0	43 (0.05)	293 (0.09)	390 (0.08)
Skin sensitisation	0	1 (0.00)	24 (0.05)	0	0	94 (0.03)	119 (0.02)
Skin swelling	1 (0.01)	2 (0.01)	12 (0.02)	0	17 (0.02)	98 (0.03)	131 (0.03)
Skin temperature	0	0	11 (0.02)	0	2 (0.00)	144 (0.04)	157 (0.03)
Skin tightness	0	2 (0.01)	10 (0.02)	0	6 (0.01)	60 (0.02)	80 (0.02)
Skin ulcer	5 (0.03)	4 (0.02)	19 (0.04)	0	27 (0.03)	45 (0.01)	104 (0.02)
Skin warm	3 (0.02)	30 (0.12)	58 (0.12)	0	61 (0.07)	517 (0.15)	670 (0.13)
Sleep apnoea syndrome	4 (0.02)	5 (0.02)	13 (0.03)	0	17 (0.02)	35 (0.01)	75 (0.01)
Sleep deficit	0	3 (0.01)	27 (0.06)	0	6 (0.01)	51 (0.02)	88 (0.02)
Sleep disorder	7 (0.04)	59 (0.23)	336 (0.69)	1 (0.22)	164 (0.19)	748 (0.22)	1335 (0.26)
Sleep terror	0	3 (0.01)	10 (0.02)	0	2 (0.00)	52 (0.02)	67 (0.01)
Slow speech	4 (0.02)	7 (0.03)	27 (0.06)	0	29 (0.03)	46 (0.01)	115 (0.02)
Sluggishness	2 (0.01)	9 (0.04)	8 (0.02)	0	15 (0.02)	48 (0.01)	86 (0.02)
Sneezing	5 (0.03)	17 (0.07)	81 (0.17)	0	29 (0.03)	538 (0.16)	671 (0.13)
Somnolence	103 (0.56)	201 (0.79)	526 (1.08)	3 (0.65)	547 (0.64)	2624 (0.78)	4086 (0.79)
Speech disorder	29 (0.16)	142 (0.56)	197 (0.40)	1 (0.22)	446 (0.52)	327 (0.10)	1208 (0.23)
Spinal pain	3 (0.02)	15 (0.06)	96 (0.20)	0	66 (0.08)	310 (0.09)	500 (0.10)
Splenic infarction	13 (0.07)	19 (0.07)	4 (0.01)	0	69 (0.08)	19 (0.01)	135 (0.03)
Splenic vein thrombosis	11 (0.06)	24 (0.09)	3 (0.01)	0	23 (0.03)	9 (0.00)	75 (0.01)
Splenomegaly	3 (0.02)	9 (0.04)	5 (0.01)	0	55 (0.06)	22 (0.01)	102 (0.02)
Spontaneous haematoma	2 (0.01)	6 (0.02)	3 (0.01)	0	23 (0.03)	43 (0.01)	79 (0.02)
Sputum discoloured	4 (0.02)	3 (0.01)	2 (0.00)	0	26 (0.03)	21 (0.01)	58 (0.01)
Staphylococcal infection	7 (0.04)	7 (0.03)	4 (0.01)	0	24 (0.03)	46 (0.01)	96 (0.02)
Staring	5 (0.03)	4 (0.02)	8 (0.02)	0	19 (0.02)	19 (0.01)	56 (0.01)
Status epilepticus	18 (0.10)	49 (0.19)	13 (0.03)	0	60 (0.07)	104 (0.03)	248 (0.05)
Stevens-Johnson syndrome	5 (0.03)	11 (0.04)	2 (0.00)	0	35 (0.04)	52 (0.02)	111 (0.02)
Still's disease	0	6 (0.02)	4 (0.01)	0	38 (0.04)	11 (0.00)	61 (0.01)
Stillbirth	11 (0.06)	0	0	2 (0.43)	19 (0.02)	18 (0.01)	51 (0.01)
Stomatitis	2 (0.01)	13 (0.05)	24 (0.05)	0	28 (0.03)	137 (0.04)	209 (0.04)
Stress	0	15 (0.06)	72 (0.15)	0	33 (0.04)	197 (0.06)	323 (0.06)
Stress cardiomyopathy	5 (0.03)	26 (0.10)	1 (0.00)	0	69 (0.08)	6 (0.00)	113 (0.02)
Stridor	2 (0.01)	58 (0.23)	0	0	68 (0.08)	67 (0.02)	203 (0.04)
Subarachnoid haemorrhage	143 (0.78)	174 (0.69)	10 (0.02)	0	164 (0.19)	32 (0.01)	544 (0.11)
Subclavian vein thrombosis	7 (0.04)	26 (0.10)	4 (0.01)	0	38 (0.04)	36 (0.01)	113 (0.02)
Subdural haematoma	23 (0.13)	63 (0.25)	4 (0.01)	0	71 (0.08)	18 (0.01)	192 (0.04)
Sudden cardiac death	101 (0.55)	1 (0.00)	0	0	0	0	102 (0.02)
Sudden death	854 (4.68)	0	0	0	0	0	855 (0.17)
Sudden hearing loss	0	3 (0.01)	171 (0.35)	0	76 (0.09)	377 (0.11)	634 (0.12)
Suffocation feeling	0	27 (0.11)	9 (0.02)	0	23 (0.03)	34 (0.01)	93 (0.02)
Suicidal ideation	4 (0.02)	53 (0.21)	44 (0.09)	0	30 (0.03)	304 (0.09)	457 (0.09)
Suicide attempt	5 (0.03)	20 (0.08)	2 (0.00)	0	7 (0.01)	33 (0.01)	69 (0.01)
Superficial vein thrombosis	4 (0.02)	56 (0.22)	24 (0.05)	0	155 (0.18)	636 (0.19)	890 (0.17)
Superior sagittal sinus thrombosis	19 (0.10)	47 (0.19)	4 (0.01)	0	40 (0.05)	12 (0.00)	126 (0.02)
Suppressed lactation	0	3 (0.01)	9 (0.02)	0	3 (0.00)	55 (0.02)	70 (0.01)
Supraventricular extrasystoles	0	8 (0.03)	5 (0.01)	0	19 (0.02)	47 (0.01)	84 (0.02)
Supraventricular tachycardia	7 (0.04)	48 (0.19)	28 (0.06)	1 (0.22)	131 (0.15)	108 (0.03)	330 (0.06)
Surgery	6 (0.03)	12 (0.05)	3 (0.01)	0	26 (0.03)	10 (0.00)	62 (0.01)
Suspected COVID-19	62 (0.34)	17 (0.07)	52 (0.11)	0	121 (0.14)	1223 (0.36)	1530 (0.30)
Sweating fever	0	3 (0.01)	83 (0.17)	0	10 (0.01)	652 (0.19)	748 (0.15)
Swelling	19 (0.10)	165 (0.65)	443 (0.91)	1 (0.22)	464 (0.54)	3328 (0.99)	4450 (0.86)
Swelling face	8 (0.04)	188 (0.74)	216 (0.44)	0	457 (0.53)	1617 (0.48)	2530 (0.49)
Swelling of eyelid	0	14 (0.06)	27 (0.06)	2 (0.43)	42 (0.05)	221 (0.07)	308 (0.06)
Swollen tongue	6 (0.03)	282 (1.11)	97 (0.20)	0	347 (0.40)	875 (0.26)	1632 (0.32)
Syncope	193 (1.06)	673 (2.66)	551 (1.13)	9 (1.96)	2057 (2.40)	11065 (3.29)	14837 (2.88)
Synovial cyst	0	2 (0.01)	10 (0.02)	0	7 (0.01)	32 (0.01)	53 (0.01)
Synovitis	0	1 (0.00)	14 (0.03)	0	13 (0.02)	23 (0.01)	51 (0.01)
Systemic inflammatory response syndrome	17 (0.09)	27 (0.11)	1 (0.00)	0	61 (0.07)	36 (0.01)	153 (0.03)
Systemic lupus erythematosus	1 (0.01)	22 (0.09)	24 (0.05)	0	42 (0.05)	180 (0.05)	274 (0.05)
Tachyarrhythmia	2 (0.01)	13 (0.05)	7 (0.01)	0	22 (0.03)	35 (0.01)	82 (0.02)
Tachycardia	93 (0.51)	601 (2.37)	544 (1.11)	4 (0.87)	2183 (2.54)	3366 (1.00)	6925 (1.35)
Tachypnoea	49 (0.27)	46 (0.18)	13 (0.03)	0	211 (0.25)	140 (0.04)	506 (0.10)
Taste disorder	3 (0.02)	21 (0.08)	181 (0.37)	0	98 (0.11)	486 (0.14)	800 (0.16)
Tearfulness	0	4 (0.02)	20 (0.04)	0	2 (0.00)	112 (0.03)	138 (0.03)
Temperature intolerance	0	3 (0.01)	23 (0.05)	0	10 (0.01)	111 (0.03)	148 (0.03)
Temperature regulation disorder	0	3 (0.01)	18 (0.04)	0	10 (0.01)	59 (0.02)	92 (0.02)
Tenderness	8 (0.04)	20 (0.08)	148 (0.30)	0	104 (0.12)	1354 (0.40)	1653 (0.32)
Tendon pain	0	2 (0.01)	39 (0.08)	0	11 (0.01)	62 (0.02)	116 (0.02)
Tendon rupture	0	0	18 (0.04)	0	10 (0.01)	36 (0.01)	67 (0.01)
Tendonitis	0	4 (0.02)	73 (0.15)	0	12 (0.01)	133 (0.04)	223 (0.04)
Tension	1 (0.01)	6 (0.02)	13 (0.03)	0	11 (0.01)	88 (0.03)	123 (0.02)
Tension headache	1 (0.01)	16 (0.06)	209 (0.43)	0	90 (0.10)	1301 (0.39)	1622 (0.32)
Testicular pain	2 (0.01)	1 (0.00)	20 (0.04)	0	14 (0.02)	115 (0.03)	155 (0.03)
Tetany	0	3 (0.01)	3 (0.01)	0	20 (0.02)	30 (0.01)	59 (0.01)
Thalamic infarction	3 (0.02)	16 (0.06)	17 (0.03)	0	53 (0.06)	10 (0.00)	102 (0.02)
Thalamus haemorrhage	2 (0.01)	12 (0.05)	7 (0.01)	0	25 (0.03)	2 (0.00)	51 (0.01)
Therapeutic response unexpected	0	2 (0.01)	11 (0.02)	0	4 (0.00)	92 (0.03)	110 (0.02)
Therapy non-responder	1 (0.01)	0	3 (0.01)	0	10 (0.01)	413 (0.12)	427 (0.08)
Thermal burn	1 (0.01)	4 (0.02)	10 (0.02)	0	3 (0.00)	50 (0.01)	69 (0.01)
Thermal burns of eye	0	0	7 (0.01)	0	2 (0.00)	49 (0.01)	58 (0.01)
Thinking abnormal	2 (0.01)	6 (0.02)	26 (0.05)	0	25 (0.03)	54 (0.02)	117 (0.02)
Thirst	2 (0.01)	34 (0.13)	180 (0.37)	1 (0.22)	76 (0.09)	1152 (0.34)	1453 (0.28)
Throat irritation	6 (0.03)	86 (0.34)	54 (0.11)	0	202 (0.24)	619 (0.18)	978 (0.19)
Throat tightness	2 (0.01)	265 (1.05)	74 (0.15)	2 (0.43)	386 (0.45)	902 (0.27)	1672 (0.32)
Thrombectomy	11 (0.06)	36 (0.14)	5 (0.01)	0	24 (0.03)	1 (0.00)	78 (0.02)
Thrombocytopenia	393 (2.16)	906 (3.57)	82 (0.17)	0	1700 (1.98)	1311 (0.39)	4740 (0.92)
Thrombocytopenic purpura	5 (0.03)	22 (0.09)	0	0	72 (0.08)	18 (0.01)	125 (0.02)
Thrombocytosis	2 (0.01)	13 (0.05)	5 (0.01)	0	31 (0.04)	18 (0.01)	72 (0.01)
Thrombophlebitis	9 (0.05)	58 (0.23)	40 (0.08)	0	114 (0.13)	478 (0.14)	713 (0.14)
Thrombosis	414 (2.27)	1217 (4.80)	347 (0.71)	4 (0.87)	1657 (1.93)	3720 (1.11)	7611 (1.48)
Thrombosis in device	2 (0.01)	26 (0.10)	3 (0.01)	0	20 (0.02)	23 (0.01)	74 (0.01)
Thrombosis with thrombocytopenia syndrome	18 (0.10)	10 (0.04)	3 (0.01)	0	22 (0.03)	12 (0.00)	77 (0.01)
Thrombotic stroke	7 (0.04)	15 (0.06)	6 (0.01)	0	22 (0.03)	3 (0.00)	55 (0.01)
Thrombotic thrombocytopenic purpura	18 (0.10)	49 (0.19)	0	0	47 (0.05)	17 (0.01)	134 (0.03)
Thunderclap headache	1 (0.01)	5 (0.02)	14 (0.03)	0	27 (0.03)	37 (0.01)	84 (0.02)
Thyroid disorder	1 (0.01)	4 (0.02)	8 (0.02)	0	9 (0.01)	32 (0.01)	54 (0.01)
Thyroiditis	0	1 (0.00)	16 (0.03)	1 (0.22)	11 (0.01)	66 (0.02)	96 (0.02)
Thyroiditis subacute	0	0	6 (0.01)	0	28 (0.03)	63 (0.02)	97 (0.02)
Tic	0	2 (0.01)	16 (0.03)	0	17 (0.02)	25 (0.01)	60 (0.01)
Tinnitus	5 (0.03)	100 (0.39)	1689 (3.46)	5 (1.09)	438 (0.51)	3823 (1.14)	6104 (1.19)
Tongue biting	1 (0.01)	9 (0.04)	5 (0.01)	0	14 (0.02)	20 (0.01)	53 (0.01)
Tongue discolouration	0	1 (0.00)	14 (0.03)	0	9 (0.01)	39 (0.01)	64 (0.01)
Tongue discomfort	0	7 (0.03)	18 (0.04)	0	23 (0.03)	86 (0.03)	135 (0.03)
Tongue disorder	0	9 (0.04)	7 (0.01)	0	19 (0.02)	81 (0.02)	119 (0.02)
Tongue oedema	3 (0.02)	39 (0.15)	13 (0.03)	0	61 (0.07)	166 (0.05)	285 (0.06)
Tongue paralysis	2 (0.01)	4 (0.02)	4 (0.01)	0	9 (0.01)	30 (0.01)	52 (0.01)
Tongue pruritus	0	12 (0.05)	3 (0.01)	0	22 (0.03)	41 (0.01)	79 (0.02)
Tongue ulceration	0	2 (0.01)	7 (0.01)	0	6 (0.01)	47 (0.01)	62 (0.01)
Tonic clonic movements	0	8 (0.03)	2 (0.00)	0	20 (0.02)	63 (0.02)	94 (0.02)
Tonic convulsion	2 (0.01)	17 (0.07)	4 (0.01)	0	38 (0.04)	64 (0.02)	131 (0.03)
Tonsillar hypertrophy	0	7 (0.03)	13 (0.03)	0	8 (0.01)	108 (0.03)	137 (0.03)
Tonsillitis	1 (0.01)	5 (0.02)	21 (0.04)	0	21 (0.02)	155 (0.05)	205 (0.04)
Toothache	3 (0.02)	14 (0.06)	67 (0.14)	0	35 (0.04)	375 (0.11)	498 (0.10)
Toxic skin eruption	1 (0.01)	0	1 (0.00)	0	12 (0.01)	78 (0.02)	93 (0.02)
Transaminases increased	2 (0.01)	8 (0.03)	7 (0.01)	0	39 (0.05)	30 (0.01)	90 (0.02)
Transient global amnesia	0	0	8 (0.02)	0	77 (0.09)	34 (0.01)	119 (0.02)
Transient ischaemic attack	24 (0.13)	283 (1.12)	101 (0.21)	0	984 (1.15)	757 (0.23)	2197 (0.43)
Transverse sinus thrombosis	9 (0.05)	22 (0.09)	5 (0.01)	0	52 (0.06)	16 (0.00)	107 (0.02)
Tremor	52 (0.29)	341 (1.35)	1591 (3.25)	1 (0.22)	1199 (1.40)	9067 (2.70)	12338 (2.40)
Tricuspid valve incompetence	2 (0.01)	10 (0.04)	5 (0.01)	1 (0.22)	24 (0.03)	13 (0.00)	60 (0.01)
Trigeminal neuralgia	0	3 (0.01)	76 (0.16)	0	62 (0.07)	218 (0.06)	360 (0.07)
Trigger finger	0	0	18 (0.04)	0	2 (0.00)	40 (0.01)	60 (0.01)
Trismus	1 (0.01)	5 (0.02)	13 (0.03)	0	26 (0.03)	85 (0.03)	132 (0.03)
Troponin I increased	2 (0.01)	11 (0.04)	0	1 (0.22)	43 (0.05)	8 (0.00)	69 (0.01)
Troponin T increased	4 (0.02)	5 (0.02)	0	0	49 (0.06)	4 (0.00)	69 (0.01)
Troponin increased	17 (0.09)	64 (0.25)	8 (0.02)	0	306 (0.36)	50 (0.01)	497 (0.10)
Tunnel vision	0	3 (0.01)	12 (0.02)	0	7 (0.01)	182 (0.05)	206 (0.04)
Type 1 diabetes mellitus	2 (0.01)	28 (0.11)	13 (0.03)	0	39 (0.05)	49 (0.01)	135 (0.03)
Type 2 diabetes mellitus	12 (0.07)	6 (0.02)	6 (0.01)	0	27 (0.03)	25 (0.01)	85 (0.02)
Type I hypersensitivity	0	6 (0.02)	0	0	13 (0.02)	125 (0.04)	150 (0.03)
Ulcer	1 (0.01)	5 (0.02)	9 (0.02)	0	11 (0.01)	49 (0.01)	76 (0.01)
Ultrasound Doppler	1 (0.01)	20 (0.08)	7 (0.01)	0	30 (0.03)	61 (0.02)	120 (0.02)
Ultrasound Doppler abnormal	5 (0.03)	87 (0.34)	11 (0.02)	0	50 (0.06)	51 (0.02)	204 (0.04)
Ultrasound scan	0	28 (0.11)	6 (0.01)	0	28 (0.03)	88 (0.03)	150 (0.03)
Ultrasound scan abnormal	2 (0.01)	16 (0.06)	4 (0.01)	0	13 (0.02)	74 (0.02)	109 (0.02)
Unevaluable event	5 (0.03)	14 (0.06)	9 (0.02)	1 (0.22)	447 (0.52)	6 (0.00)	483 (0.09)
Unresponsive to stimuli	254 (1.39)	120 (0.47)	20 (0.04)	0	193 (0.22)	695 (0.21)	1405 (0.27)
Upper gastrointestinal haemorrhage	12 (0.07)	7 (0.03)	3 (0.01)	0	11 (0.01)	21 (0.01)	58 (0.01)
Upper respiratory tract infection	5 (0.03)	7 (0.03)	9 (0.02)	0	16 (0.02)	28 (0.01)	68 (0.01)
Urinary incontinence	10 (0.05)	45 (0.18)	68 (0.14)	0	115 (0.13)	178 (0.05)	442 (0.09)
Urinary retention	10 (0.05)	29 (0.11)	53 (0.11)	0	131 (0.15)	174 (0.05)	418 (0.08)
Urinary tract infection	78 (0.43)	61 (0.24)	82 (0.17)	0	350 (0.41)	439 (0.13)	1078 (0.21)
Urine output decreased	6 (0.03)	5 (0.02)	4 (0.01)	0	12 (0.01)	26 (0.01)	57 (0.01)
Urosepsis	25 (0.14)	12 (0.05)	0	0	31 (0.04)	5 (0.00)	77 (0.01)
Urticaria	6 (0.03)	317 (1.25)	349 (0.71)	1 (0.22)	963 (1.12)	4165 (1.24)	5863 (1.14)
Urticaria chronic	0	8 (0.03)	15 (0.03)	0	8 (0.01)	64 (0.02)	96 (0.02)
Uterine haemorrhage	0	6 (0.02)	7 (0.01)	1 (0.22)	20 (0.02)	128 (0.04)	165 (0.03)
Uterine pain	0	1 (0.00)	13 (0.03)	0	7 (0.01)	38 (0.01)	60 (0.01)
Uterine spasm	0	1 (0.00)	8 (0.02)	0	6 (0.01)	44 (0.01)	59 (0.01)
Uveitis	0	1 (0.00)	43 (0.09)	0	23 (0.03)	184 (0.05)	256 (0.05)
VIth nerve paralysis	0	2 (0.01)	26 (0.05)	0	38 (0.04)	59 (0.02)	127 (0.02)
Vaccination complication	34 (0.19)	46 (0.18)	61 (0.12)	0	153 (0.18)	205 (0.06)	517 (0.10)
Vaccination failure	630 (3.45)	177 (0.70)	14 (0.03)	0	1447 (1.69)	16849 (5.01)	19313 (3.75)
Vaccination site bruising	1 (0.01)	2 (0.01)	36 (0.07)	0	13 (0.02)	224 (0.07)	278 (0.05)
Vaccination site cellulitis	0	1 (0.00)	5 (0.01)	0	10 (0.01)	114 (0.03)	131 (0.03)
Vaccination site discolouration	1 (0.01)	2 (0.01)	9 (0.02)	0	8 (0.01)	35 (0.01)	56 (0.01)
Vaccination site discomfort	0	2 (0.01)	13 (0.03)	0	10 (0.01)	95 (0.03)	121 (0.02)
Vaccination site erythema	5 (0.03)	25 (0.10)	251 (0.51)	0	140 (0.16)	1361 (0.40)	1789 (0.35)
Vaccination site haematoma	2 (0.01)	1 (0.00)	22 (0.05)	0	13 (0.02)	66 (0.02)	104 (0.02)
Vaccination site haemorrhage	1 (0.01)	2 (0.01)	5 (0.01)	0	11 (0.01)	75 (0.02)	97 (0.02)
Vaccination site hypoaesthesia	0	5 (0.02)	17 (0.03)	0	10 (0.01)	81 (0.02)	113 (0.02)
Vaccination site induration	0	1 (0.00)	37 (0.08)	0	19 (0.02)	163 (0.05)	221 (0.04)
Vaccination site infection	0	1 (0.00)	8 (0.02)	0	5 (0.01)	47 (0.01)	61 (0.01)
Vaccination site inflammation	1 (0.01)	2 (0.01)	29 (0.06)	0	16 (0.02)	233 (0.07)	281 (0.05)
Vaccination site joint movement impairment	0	0	31 (0.06)	0	3 (0.00)	52 (0.02)	86 (0.02)
Vaccination site joint pain	0	1 (0.00)	32 (0.07)	0	5 (0.01)	51 (0.02)	89 (0.02)
Vaccination site lymphadenopathy	0	0	4 (0.01)	1 (0.22)	10 (0.01)	114 (0.03)	129 (0.03)
Vaccination site mass	0	9 (0.04)	78 (0.16)	0	20 (0.02)	630 (0.19)	742 (0.14)
Vaccination site movement impairment	0	6 (0.02)	173 (0.35)	0	47 (0.05)	233 (0.07)	462 (0.09)
Vaccination site oedema	0	4 (0.02)	101 (0.21)	0	34 (0.04)	216 (0.06)	357 (0.07)
Vaccination site pain	42 (0.23)	133 (0.52)	1416 (2.90)	0	610 (0.71)	6080 (1.81)	8339 (1.62)
Vaccination site paraesthesia	0	5 (0.02)	17 (0.03)	0	7 (0.01)	81 (0.02)	111 (0.02)
Vaccination site pruritus	0	14 (0.06)	109 (0.22)	0	60 (0.07)	517 (0.15)	704 (0.14)
Vaccination site rash	2 (0.01)	5 (0.02)	28 (0.06)	0	34 (0.04)	370 (0.11)	440 (0.09)
Vaccination site reaction	3 (0.02)	9 (0.04)	71 (0.15)	0	86 (0.10)	325 (0.10)	497 (0.10)
Vaccination site swelling	4 (0.02)	20 (0.08)	242 (0.50)	1 (0.22)	152 (0.18)	1268 (0.38)	1698 (0.33)
Vaccination site urticaria	0	5 (0.02)	5 (0.01)	0	19 (0.02)	74 (0.02)	106 (0.02)
Vaccination site warmth	0	4 (0.02)	107 (0.22)	0	44 (0.05)	701 (0.21)	857 (0.17)
Vaccine breakthrough infection	30 (0.16)	4 (0.02)	1 (0.00)	0	158 (0.18)	103 (0.03)	317 (0.06)
Vaginal discharge	1 (0.01)	2 (0.01)	6 (0.01)	2 (0.43)	13 (0.02)	91 (0.03)	115 (0.02)
Vaginal haemorrhage	1 (0.01)	51 (0.20)	103 (0.21)	15 (3.26)	170 (0.20)	1477 (0.44)	1823 (0.35)
Varicella	0	3 (0.01)	7 (0.01)	0	7 (0.01)	40 (0.01)	58 (0.01)
Varicose vein	0	17 (0.07)	26 (0.05)	0	18 (0.02)	157 (0.05)	220 (0.04)
Vascular headache	0	4 (0.02)	21 (0.04)	0	4 (0.00)	54 (0.02)	84 (0.02)
Vascular pain	1 (0.01)	13 (0.05)	27 (0.06)	0	21 (0.02)	145 (0.04)	211 (0.04)
Vascular purpura	1 (0.01)	0	0	0	27 (0.03)	27 (0.01)	55 (0.01)
Vasculitis	20 (0.11)	49 (0.19)	34 (0.07)	0	162 (0.19)	208 (0.06)	493 (0.10)
Vasodilatation	1 (0.01)	9 (0.04)	34 (0.07)	1 (0.22)	22 (0.03)	128 (0.04)	199 (0.04)
Vein disorder	0	5 (0.02)	10 (0.02)	0	11 (0.01)	48 (0.01)	75 (0.01)
Vena cava thrombosis	7 (0.04)	19 (0.07)	1 (0.00)	1 (0.22)	20 (0.02)	7 (0.00)	60 (0.01)
Venous occlusion	2 (0.01)	5 (0.02)	7 (0.01)	0	29 (0.03)	18 (0.01)	63 (0.01)
Venous thrombosis	12 (0.07)	98 (0.39)	26 (0.05)	0	154 (0.18)	239 (0.07)	544 (0.11)
Venous thrombosis limb	5 (0.03)	82 (0.32)	19 (0.04)	0	179 (0.21)	347 (0.10)	641 (0.12)
Ventricular extrasystoles	2 (0.01)	22 (0.09)	28 (0.06)	0	95 (0.11)	159 (0.05)	317 (0.06)
Ventricular fibrillation	89 (0.49)	82 (0.32)	2 (0.00)	0	37 (0.04)	9 (0.00)	246 (0.05)
Ventricular hypokinesia	1 (0.01)	14 (0.06)	3 (0.01)	0	41 (0.05)	9 (0.00)	77 (0.01)
Ventricular tachycardia	31 (0.17)	72 (0.28)	4 (0.01)	0	90 (0.10)	48 (0.01)	263 (0.05)
Vertebral artery dissection	2 (0.01)	15 (0.06)	2 (0.00)	0	25 (0.03)	10 (0.00)	54 (0.01)
Vertigo	12 (0.07)	176 (0.69)	1131 (2.31)	2 (0.43)	916 (1.07)	3313 (0.99)	5619 (1.09)
Vertigo positional	0	5 (0.02)	57 (0.12)	0	65 (0.08)	188 (0.06)	317 (0.06)
Vestibular disorder	0	2 (0.01)	32 (0.07)	0	29 (0.03)	33 (0.01)	97 (0.02)
Vestibular migraine	0	0	23 (0.05)	0	12 (0.01)	35 (0.01)	70 (0.01)
Vestibular neuronitis	0	5 (0.02)	53 (0.11)	1 (0.22)	175 (0.20)	148 (0.04)	385 (0.07)
Viral infection	5 (0.03)	13 (0.05)	35 (0.07)	0	68 (0.08)	97 (0.03)	223 (0.04)
Viral rash	0	0	1 (0.00)	0	4 (0.00)	71 (0.02)	76 (0.01)
Vision blurred	20 (0.11)	200 (0.79)	939 (1.92)	5 (1.09)	759 (0.88)	3197 (0.95)	5175 (1.01)
Visual acuity reduced	1 (0.01)	7 (0.03)	49 (0.10)	0	45 (0.05)	136 (0.04)	243 (0.05)
Visual field defect	1 (0.01)	15 (0.06)	74 (0.15)	0	97 (0.11)	112 (0.03)	313 (0.06)
Visual impairment	22 (0.12)	134 (0.53)	613 (1.25)	2 (0.43)	745 (0.87)	1265 (0.38)	2850 (0.55)
Vitreous detachment	0	0	32 (0.07)	0	12 (0.01)	155 (0.05)	201 (0.04)
Vitreous floaters	2 (0.01)	2 (0.01)	68 (0.14)	0	28 (0.03)	218 (0.06)	320 (0.06)
Vitreous haemorrhage	0	1 (0.00)	7 (0.01)	0	13 (0.02)	30 (0.01)	57 (0.01)
Vomiting	497 (2.73)	841 (3.32)	2439 (4.99)	3 (0.65)	3566 (4.15)	12939 (3.85)	20621 (4.01)
Vomiting projectile	3 (0.02)	3 (0.01)	40 (0.08)	0	16 (0.02)	154 (0.05)	216 (0.04)
Vulvovaginal candidiasis	0	0	8 (0.02)	0	3 (0.00)	47 (0.01)	58 (0.01)
Vulvovaginal pain	0	2 (0.01)	14 (0.03)	0	5 (0.01)	47 (0.01)	68 (0.01)
Walking aid user	6 (0.03)	13 (0.05)	38 (0.08)	0	26 (0.03)	8 (0.00)	94 (0.02)
Walking disability	1 (0.01)	4 (0.02)	27 (0.06)	0	18 (0.02)	20 (0.01)	75 (0.01)
Weight bearing difficulty	1 (0.01)	3 (0.01)	22 (0.05)	1 (0.22)	42 (0.05)	27 (0.01)	100 (0.02)
Weight decreased	23 (0.13)	59 (0.23)	201 (0.41)	0	259 (0.30)	413 (0.12)	1006 (0.20)
Weight increased	4 (0.02)	12 (0.05)	33 (0.07)	0	50 (0.06)	88 (0.03)	194 (0.04)
Wheezing	27 (0.15)	155 (0.61)	112 (0.23)	0	329 (0.38)	876 (0.26)	1544 (0.30)
White blood cell count decreased	0	15 (0.06)	10 (0.02)	0	57 (0.07)	63 (0.02)	157 (0.03)
White blood cell count increased	12 (0.07)	32 (0.13)	22 (0.05)	0	139 (0.16)	58 (0.02)	291 (0.06)
White matter lesion	0	10 (0.04)	15 (0.03)	0	35 (0.04)	5 (0.00)	70 (0.01)
Withdrawal syndrome	0	2 (0.01)	8 (0.02)	0	3 (0.00)	72 (0.02)	85 (0.02)
Wound	0	4 (0.02)	9 (0.02)	0	28 (0.03)	46 (0.01)	92 (0.02)
X-ray	2 (0.01)	22 (0.09)	11 (0.02)	0	13 (0.02)	13 (0.00)	61 (0.01)
Yawning	0	6 (0.02)	9 (0.02)	0	8 (0.01)	70 (0.02)	95 (0.02)
Yellow skin	0	13 (0.05)	6 (0.01)	0	8 (0.01)	28 (0.01)	57 (0.01)