Eudravigilance C-19 - Tous les vaccins

Liste des effets indésirables (uniquement ceux qui apparaissent dans plus de 50 cas graves)

PT

Décès

18235 (%)

Mise en jeu du pronostic vital

25346 (%)

Invalidité ou incapacité

48879 (%)

Anomalies congénitales

460 (%)

Hospitalisation

85857 (%)

Médicalement significatif

336072 (%)

Cas Graves

514849 (%)

Abdominal discomfort 26 (0.14) 54 (0.21) 281 (0.57) 1 (0.22) 224 (0.26) 1622 (0.48) 2237 (0.43)
Abdominal distension 22 (0.12) 49 (0.19) 180 (0.37) 1 (0.22) 155 (0.18) 784 (0.23) 1204 (0.23)
Abdominal pain 173 (0.95) 357 (1.41) 991 (2.03) 10 (2.17) 1500 (1.75) 4725 (1.41) 7892 (1.53)
Abdominal pain lower 5 (0.03) 29 (0.11) 72 (0.15) 0 192 (0.22) 350 (0.10) 654 (0.13)
Abdominal pain upper 83 (0.46) 182 (0.72) 880 (1.80) 2 (0.43) 789 (0.92) 5604 (1.67) 7585 (1.47)
Abdominal rigidity 3 (0.02) 4 (0.02) 13 (0.03) 0 10 (0.01) 54 (0.02) 84 (0.02)
Abdominal tenderness 3 (0.02) 1 (0.00) 6 (0.01) 0 32 (0.04) 33 (0.01) 80 (0.02)
Abnormal behaviour 7 (0.04) 11 (0.04) 13 (0.03) 0 59 (0.07) 40 (0.01) 139 (0.03)
Abnormal dreams 1 (0.01) 7 (0.03) 50 (0.10) 0 12 (0.01) 335 (0.10) 406 (0.08)
Abnormal faeces 0 3 (0.01) 7 (0.01) 0 65 (0.08) 30 (0.01) 105 (0.02)
Abnormal loss of weight 1 (0.01) 15 (0.06) 35 (0.07) 0 23 (0.03) 49 (0.01) 128 (0.02)
Abnormal sensation in eye 0 0 14 (0.03) 0 11 (0.01) 48 (0.01) 73 (0.01)
Abortion 4 (0.02) 3 (0.01) 0 2 (0.43) 16 (0.02) 44 (0.01) 70 (0.01)
Abortion missed 1 (0.01) 3 (0.01) 0 6 (1.30) 16 (0.02) 68 (0.02) 95 (0.02)
Abortion spontaneous 8 (0.04) 44 (0.17) 61 (0.12) 177 (38.48) 183 (0.21) 1355 (0.40) 1836 (0.36)
Abscess 0 5 (0.02) 14 (0.03) 0 51 (0.06) 57 (0.02) 133 (0.03)
Acne 1 (0.01) 7 (0.03) 22 (0.05) 0 11 (0.01) 184 (0.05) 226 (0.04)
Activated partial thromboplastin time prolonged 5 (0.03) 50 (0.20) 9 (0.02) 0 43 (0.05) 56 (0.02) 168 (0.03)
Acute abdomen 12 (0.07) 2 (0.01) 3 (0.01) 0 19 (0.02) 19 (0.01) 56 (0.01)
Acute coronary syndrome 54 (0.30) 76 (0.30) 2 (0.00) 0 200 (0.23) 20 (0.01) 363 (0.07)
Acute disseminated encephalomyelitis 5 (0.03) 18 (0.07) 27 (0.06) 0 87 (0.10) 26 (0.01) 174 (0.03)
Acute kidney injury 195 (1.07) 160 (0.63) 23 (0.05) 0 469 (0.55) 106 (0.03) 1038 (0.20)
Acute myocardial infarction 309 (1.69) 453 (1.79) 15 (0.03) 0 575 (0.67) 71 (0.02) 1466 (0.28)
Acute polyneuropathy 0 4 (0.02) 3 (0.01) 0 46 (0.05) 9 (0.00) 63 (0.01)
Acute pulmonary oedema 26 (0.14) 21 (0.08) 0 0 58 (0.07) 7 (0.00) 119 (0.02)
Acute respiratory distress syndrome 94 (0.52) 37 (0.15) 1 (0.00) 0 53 (0.06) 22 (0.01) 229 (0.04)
Acute respiratory failure 208 (1.14) 95 (0.37) 4 (0.01) 0 276 (0.32) 14 (0.00) 616 (0.12)
Administration site pain 2 (0.01) 55 (0.22) 59 (0.12) 1 (0.22) 11 (0.01) 70 (0.02) 200 (0.04)
Adnexa uteri pain 0 6 (0.02) 26 (0.05) 1 (0.22) 10 (0.01) 105 (0.03) 148 (0.03)
Adrenal insufficiency 2 (0.01) 10 (0.04) 6 (0.01) 0 23 (0.03) 24 (0.01) 66 (0.01)
Adrenocortical insufficiency acute 1 (0.01) 22 (0.09) 6 (0.01) 0 27 (0.03) 26 (0.01) 82 (0.02)
Adverse drug reaction 1 (0.01) 4 (0.02) 27 (0.06) 0 21 (0.02) 124 (0.04) 179 (0.03)
Adverse event 5 (0.03) 7 (0.03) 6 (0.01) 0 98 (0.11) 47 (0.01) 169 (0.03)
Adverse event following immunisation 113 (0.62) 0 2 (0.00) 0 2 (0.00) 3 (0.00) 120 (0.02)
Adverse reaction 2 (0.01) 7 (0.03) 12 (0.02) 0 18 (0.02) 24 (0.01) 63 (0.01)
Ageusia 23 (0.13) 38 (0.15) 323 (0.66) 1 (0.22) 207 (0.24) 1101 (0.33) 1709 (0.33)
Aggression 9 (0.05) 16 (0.06) 19 (0.04) 0 41 (0.05) 29 (0.01) 115 (0.02)
Agitation 32 (0.18) 46 (0.18) 56 (0.11) 0 96 (0.11) 233 (0.07) 482 (0.09)
Alanine aminotransferase increased 4 (0.02) 19 (0.07) 15 (0.03) 0 63 (0.07) 74 (0.02) 189 (0.04)
Allergy to vaccine 1 (0.01) 27 (0.11) 11 (0.02) 0 57 (0.07) 184 (0.05) 289 (0.06)
Allodynia 0 1 (0.00) 24 (0.05) 0 8 (0.01) 49 (0.01) 85 (0.02)
Alopecia 0 21 (0.08) 126 (0.26) 2 (0.43) 46 (0.05) 477 (0.14) 678 (0.13)
Alopecia areata 0 0 12 (0.02) 0 4 (0.00) 68 (0.02) 85 (0.02)
Altered state of consciousness 72 (0.39) 43 (0.17) 32 (0.07) 0 252 (0.29) 277 (0.08) 764 (0.15)
Amaurosis fugax 0 3 (0.01) 3 (0.01) 0 24 (0.03) 48 (0.01) 80 (0.02)
Amenorrhoea 0 23 (0.09) 184 (0.38) 5 (1.09) 36 (0.04) 756 (0.22) 1009 (0.20)
Amnesia 12 (0.07) 109 (0.43) 253 (0.52) 0 279 (0.32) 471 (0.14) 1146 (0.22)
Anaemia 42 (0.23) 115 (0.45) 70 (0.14) 0 301 (0.35) 231 (0.07) 804 (0.16)
Anal haemorrhage 1 (0.01) 3 (0.01) 7 (0.01) 0 9 (0.01) 38 (0.01) 58 (0.01)
Anal incontinence 9 (0.05) 15 (0.06) 27 (0.06) 0 51 (0.06) 43 (0.01) 155 (0.03)
Anaphylactic reaction 41 (0.22) 1424 (5.62) 72 (0.15) 1 (0.22) 2035 (2.37) 4669 (1.39) 8349 (1.62)
Anaphylactic shock 19 (0.10) 390 (1.54) 20 (0.04) 0 358 (0.42) 475 (0.14) 1290 (0.25)
Anaphylactoid reaction 1 (0.01) 18 (0.07) 3 (0.01) 0 43 (0.05) 209 (0.06) 277 (0.05)
Aneurysm 18 (0.10) 18 (0.07) 3 (0.01) 1 (0.22) 21 (0.02) 11 (0.00) 78 (0.02)
Anger 3 (0.02) 17 (0.07) 21 (0.04) 0 10 (0.01) 85 (0.03) 140 (0.03)
Angina pectoris 17 (0.09) 124 (0.49) 123 (0.25) 1 (0.22) 421 (0.49) 1111 (0.33) 1851 (0.36)
Angina unstable 0 9 (0.04) 3 (0.01) 0 37 (0.04) 23 (0.01) 73 (0.01)
Angioedema 2 (0.01) 183 (0.72) 41 (0.08) 0 271 (0.32) 1716 (0.51) 2256 (0.44)
Angiogram 1 (0.01) 28 (0.11) 7 (0.01) 0 17 (0.02) 14 (0.00) 67 (0.01)
Angiogram cerebral abnormal 4 (0.02) 28 (0.11) 7 (0.01) 0 23 (0.03) 1 (0.00) 63 (0.01)
Angiogram pulmonary abnormal 6 (0.03) 62 (0.24) 1 (0.00) 0 54 (0.06) 2 (0.00) 127 (0.02)
Ankylosing spondylitis 0 0 21 (0.04) 0 6 (0.01) 87 (0.03) 115 (0.02)
Anosmia 16 (0.09) 26 (0.10) 198 (0.41) 0 133 (0.15) 523 (0.16) 909 (0.18)
Anovulatory cycle 0 0 14 (0.03) 0 2 (0.00) 35 (0.01) 52 (0.01)
Anticoagulant therapy 16 (0.09) 146 (0.58) 10 (0.02) 0 117 (0.14) 12 (0.00) 302 (0.06)
Antiphospholipid syndrome 1 (0.01) 19 (0.07) 5 (0.01) 0 17 (0.02) 30 (0.01) 77 (0.01)
Anuria 14 (0.08) 8 (0.03) 1 (0.00) 0 15 (0.02) 22 (0.01) 72 (0.01)
Anxiety 21 (0.12) 139 (0.55) 490 (1.00) 3 (0.65) 477 (0.56) 1750 (0.52) 2916 (0.57)
Aortic aneurysm 18 (0.10) 8 (0.03) 5 (0.01) 0 22 (0.03) 5 (0.00) 62 (0.01)
Aortic dissection 71 (0.39) 39 (0.15) 1 (0.00) 0 17 (0.02) 10 (0.00) 140 (0.03)
Aortic thrombosis 18 (0.10) 35 (0.14) 1 (0.00) 0 30 (0.03) 4 (0.00) 97 (0.02)
Apathy 3 (0.02) 11 (0.04) 49 (0.10) 0 49 (0.06) 107 (0.03) 227 (0.04)
Aphasia 69 (0.38) 228 (0.90) 185 (0.38) 0 542 (0.63) 297 (0.09) 1412 (0.27)
Aphonia 3 (0.02) 21 (0.08) 38 (0.08) 0 49 (0.06) 194 (0.06) 313 (0.06)
Aphthous ulcer 3 (0.02) 7 (0.03) 17 (0.03) 0 19 (0.02) 123 (0.04) 171 (0.03)
Apnoea 35 (0.19) 12 (0.05) 3 (0.01) 0 20 (0.02) 59 (0.02) 144 (0.03)
Appendicitis 2 (0.01) 124 (0.49) 14 (0.03) 0 391 (0.46) 126 (0.04) 662 (0.13)
Appendicitis perforated 0 30 (0.12) 0 0 33 (0.04) 4 (0.00) 67 (0.01)
Appetite disorder 0 1 (0.00) 17 (0.03) 0 6 (0.01) 44 (0.01) 69 (0.01)
Application site erythema 0 0 2 (0.00) 0 2 (0.00) 57 (0.02) 63 (0.01)
Application site pain 1 (0.01) 2 (0.01) 6 (0.01) 0 12 (0.01) 107 (0.03) 131 (0.03)
Areflexia 5 (0.03) 17 (0.07) 28 (0.06) 0 61 (0.07) 5 (0.00) 128 (0.02)
Arrhythmia 113 (0.62) 184 (0.73) 145 (0.30) 0 962 (1.12) 1872 (0.56) 3355 (0.65)
Arterial occlusive disease 7 (0.04) 22 (0.09) 14 (0.03) 0 47 (0.05) 18 (0.01) 111 (0.02)
Arterial thrombosis 16 (0.09) 38 (0.15) 10 (0.02) 0 40 (0.05) 31 (0.01) 145 (0.03)
Arteriosclerosis 42 (0.23) 14 (0.06) 5 (0.01) 0 41 (0.05) 4 (0.00) 116 (0.02)
Arteriosclerosis coronary artery 43 (0.24) 7 (0.03) 0 0 14 (0.02) 1 (0.00) 67 (0.01)
Arthralgia 96 (0.53) 525 (2.07) 8243 (16.86) 7 (1.52) 2037 (2.37) 24467 (7.28) 35529 (6.90)
Arthritis 2 (0.01) 18 (0.07) 339 (0.69) 0 138 (0.16) 718 (0.21) 1224 (0.24)
Arthritis reactive 0 3 (0.01) 52 (0.11) 0 30 (0.03) 129 (0.04) 215 (0.04)
Arthropathy 1 (0.01) 4 (0.02) 53 (0.11) 0 19 (0.02) 74 (0.02) 151 (0.03)
Ascites 20 (0.11) 20 (0.08) 3 (0.01) 2 (0.43) 49 (0.06) 22 (0.01) 136 (0.03)
Aspartate aminotransferase increased 3 (0.02) 12 (0.05) 1 (0.00) 0 53 (0.06) 38 (0.01) 117 (0.02)
Asphyxia 25 (0.14) 15 (0.06) 2 (0.00) 0 13 (0.02) 63 (0.02) 131 (0.03)
Aspiration 43 (0.24) 15 (0.06) 2 (0.00) 0 18 (0.02) 13 (0.00) 109 (0.02)
Asthenia 507 (2.78) 750 (2.96) 2462 (5.04) 3 (0.65) 3435 (4.00) 8436 (2.51) 15942 (3.10)
Asthenopia 0 4 (0.02) 75 (0.15) 0 20 (0.02) 347 (0.10) 448 (0.09)
Asthma 17 (0.09) 155 (0.61) 186 (0.38) 0 335 (0.39) 1054 (0.31) 1764 (0.34)
Asthmatic crisis 0 19 (0.07) 1 (0.00) 0 19 (0.02) 83 (0.02) 125 (0.02)
Asymptomatic COVID-19 12 (0.07) 2 (0.01) 1 (0.00) 0 75 (0.09) 528 (0.16) 623 (0.12)
Ataxia 4 (0.02) 29 (0.11) 50 (0.10) 0 117 (0.14) 45 (0.01) 267 (0.05)
Atelectasis 14 (0.08) 26 (0.10) 7 (0.01) 0 97 (0.11) 12 (0.00) 166 (0.03)
Atrial fibrillation 125 (0.69) 414 (1.63) 131 (0.27) 0 1268 (1.48) 1414 (0.42) 3480 (0.68)
Atrial flutter 5 (0.03) 34 (0.13) 16 (0.03) 0 120 (0.14) 74 (0.02) 260 (0.05)
Atrioventricular block 9 (0.05) 46 (0.18) 7 (0.01) 1 (0.22) 59 (0.07) 27 (0.01) 152 (0.03)
Atrioventricular block complete 12 (0.07) 50 (0.20) 4 (0.01) 0 45 (0.05) 8 (0.00) 125 (0.02)
Atypical pneumonia 7 (0.04) 8 (0.03) 0 0 38 (0.04) 24 (0.01) 82 (0.02)
Auditory disorder 0 4 (0.02) 19 (0.04) 0 17 (0.02) 27 (0.01) 69 (0.01)
Aura 0 0 8 (0.02) 0 10 (0.01) 44 (0.01) 62 (0.01)
Autoimmune disorder 9 (0.05) 27 (0.11) 84 (0.17) 0 71 (0.08) 278 (0.08) 501 (0.10)
Autoimmune haemolytic anaemia 8 (0.04) 24 (0.09) 3 (0.01) 0 52 (0.06) 28 (0.01) 119 (0.02)
Autoimmune hepatitis 5 (0.03) 15 (0.06) 6 (0.01) 0 56 (0.07) 40 (0.01) 124 (0.02)
Autoimmune thyroiditis 0 5 (0.02) 16 (0.03) 0 13 (0.02) 123 (0.04) 159 (0.03)
Autonomic nervous system imbalance 3 (0.02) 15 (0.06) 42 (0.09) 0 14 (0.02) 36 (0.01) 112 (0.02)
Axillary mass 0 3 (0.01) 41 (0.08) 0 17 (0.02) 230 (0.07) 294 (0.06)
Axillary pain 2 (0.01) 22 (0.09) 300 (0.61) 0 75 (0.09) 2324 (0.69) 2730 (0.53)
Back pain 94 (0.52) 281 (1.11) 1512 (3.09) 6 (1.30) 1019 (1.19) 6224 (1.85) 9232 (1.79)
Bacterial infection 11 (0.06) 5 (0.02) 8 (0.02) 0 37 (0.04) 44 (0.01) 110 (0.02)
Balance disorder 26 (0.14) 135 (0.53) 635 (1.30) 1 (0.22) 525 (0.61) 1188 (0.35) 2575 (0.50)
Basedow's disease 0 11 (0.04) 25 (0.05) 0 36 (0.04) 144 (0.04) 220 (0.04)
Bed rest 1 (0.01) 0 32 (0.07) 0 6 (0.01) 22 (0.01) 61 (0.01)
Bedridden 18 (0.10) 24 (0.09) 105 (0.21) 0 50 (0.06) 198 (0.06) 413 (0.08)
Bell's palsy 1 (0.01) 33 (0.13) 461 (0.94) 3 (0.65) 497 (0.58) 3267 (0.97) 4301 (0.84)
Biliary colic 2 (0.01) 4 (0.02) 9 (0.02) 0 21 (0.02) 31 (0.01) 68 (0.01)
Bladder disorder 0 1 (0.00) 14 (0.03) 0 17 (0.02) 24 (0.01) 59 (0.01)
Bladder pain 0 2 (0.01) 20 (0.04) 0 5 (0.01) 68 (0.02) 96 (0.02)
Blepharitis 0 3 (0.01) 8 (0.02) 0 4 (0.00) 37 (0.01) 52 (0.01)
Blepharospasm 0 6 (0.02) 45 (0.09) 0 27 (0.03) 137 (0.04) 217 (0.04)
Blindness 7 (0.04) 67 (0.26) 284 (0.58) 0 159 (0.19) 666 (0.20) 1235 (0.24)
Blindness transient 0 13 (0.05) 20 (0.04) 0 36 (0.04) 209 (0.06) 286 (0.06)
Blindness unilateral 2 (0.01) 24 (0.09) 159 (0.33) 0 62 (0.07) 142 (0.04) 410 (0.08)
Blister 5 (0.03) 36 (0.14) 125 (0.26) 0 122 (0.14) 680 (0.20) 987 (0.19)
Blood bilirubin increased 2 (0.01) 15 (0.06) 2 (0.00) 0 28 (0.03) 15 (0.00) 65 (0.01)
Blood blister 0 9 (0.04) 19 (0.04) 0 22 (0.03) 70 (0.02) 123 (0.02)
Blood cholesterol increased 0 7 (0.03) 8 (0.02) 0 14 (0.02) 26 (0.01) 56 (0.01)
Blood creatine phosphokinase increased 3 (0.02) 13 (0.05) 10 (0.02) 0 121 (0.14) 56 (0.02) 227 (0.04)
Blood creatinine increased 8 (0.04) 18 (0.07) 9 (0.02) 0 55 (0.06) 17 (0.01) 116 (0.02)
Blood disorder 4 (0.02) 8 (0.03) 1 (0.00) 0 13 (0.02) 24 (0.01) 52 (0.01)
Blood fibrinogen increased 2 (0.01) 12 (0.05) 2 (0.00) 0 26 (0.03) 22 (0.01) 76 (0.01)
Blood glucose decreased 6 (0.03) 24 (0.09) 12 (0.02) 0 29 (0.03) 74 (0.02) 153 (0.03)
Blood glucose fluctuation 2 (0.01) 10 (0.04) 7 (0.01) 0 11 (0.01) 40 (0.01) 72 (0.01)
Blood glucose increased 17 (0.09) 40 (0.16) 42 (0.09) 0 112 (0.13) 288 (0.09) 526 (0.10)
Blood iron decreased 1 (0.01) 2 (0.01) 13 (0.03) 0 5 (0.01) 41 (0.01) 69 (0.01)
Blood lactate dehydrogenase increased 2 (0.01) 5 (0.02) 0 0 40 (0.05) 9 (0.00) 65 (0.01)
Blood potassium decreased 1 (0.01) 17 (0.07) 3 (0.01) 0 63 (0.07) 17 (0.01) 108 (0.02)
Blood pressure abnormal 7 (0.04) 22 (0.09) 19 (0.04) 0 54 (0.06) 96 (0.03) 206 (0.04)
Blood pressure decreased 58 (0.32) 168 (0.66) 102 (0.21) 1 (0.22) 383 (0.45) 782 (0.23) 1560 (0.30)
Blood pressure diastolic increased 0 2 (0.01) 8 (0.02) 0 11 (0.01) 27 (0.01) 51 (0.01)
Blood pressure fluctuation 3 (0.02) 48 (0.19) 44 (0.09) 0 90 (0.10) 123 (0.04) 329 (0.06)
Blood pressure increased 31 (0.17) 272 (1.07) 247 (0.51) 1 (0.22) 1034 (1.20) 3092 (0.92) 4789 (0.93)
Blood pressure measurement 0 14 (0.06) 13 (0.03) 0 24 (0.03) 72 (0.02) 124 (0.02)
Blood pressure systolic increased 0 8 (0.03) 3 (0.01) 0 36 (0.04) 101 (0.03) 158 (0.03)
Blood sodium decreased 3 (0.02) 5 (0.02) 4 (0.01) 0 46 (0.05) 8 (0.00) 71 (0.01)
Blood test 4 (0.02) 100 (0.39) 42 (0.09) 0 74 (0.09) 112 (0.03) 332 (0.06)
Blood test abnormal 2 (0.01) 23 (0.09) 39 (0.08) 0 62 (0.07) 86 (0.03) 216 (0.04)
Blood urine 1 (0.01) 3 (0.01) 3 (0.01) 0 10 (0.01) 42 (0.01) 60 (0.01)
Blood urine present 4 (0.02) 13 (0.05) 17 (0.03) 0 41 (0.05) 150 (0.04) 229 (0.04)
Body temperature 0 8 (0.03) 74 (0.15) 0 14 (0.02) 724 (0.22) 822 (0.16)
Body temperature abnormal 1 (0.01) 4 (0.02) 28 (0.06) 0 7 (0.01) 145 (0.04) 187 (0.04)
Body temperature decreased 6 (0.03) 14 (0.06) 38 (0.08) 0 16 (0.02) 163 (0.05) 241 (0.05)
Body temperature fluctuation 1 (0.01) 3 (0.01) 45 (0.09) 0 11 (0.01) 187 (0.06) 247 (0.05)
Body temperature increased 29 (0.16) 30 (0.12) 163 (0.33) 1 (0.22) 234 (0.27) 1210 (0.36) 1684 (0.33)
Bone pain 6 (0.03) 62 (0.24) 354 (0.72) 0 98 (0.11) 1226 (0.36) 1756 (0.34)
Bradycardia 48 (0.26) 105 (0.41) 39 (0.08) 1 (0.22) 210 (0.24) 709 (0.21) 1170 (0.23)
Bradykinesia 1 (0.01) 6 (0.02) 13 (0.03) 0 11 (0.01) 50 (0.01) 83 (0.02)
Bradyphrenia 0 4 (0.02) 37 (0.08) 0 19 (0.02) 110 (0.03) 171 (0.03)
Brain death 67 (0.37) 4 (0.02) 1 (0.00) 0 0 0 78 (0.02)
Brain injury 46 (0.25) 31 (0.12) 11 (0.02) 0 20 (0.02) 29 (0.01) 159 (0.03)
Brain natriuretic peptide increased 3 (0.02) 9 (0.04) 1 (0.00) 0 26 (0.03) 4 (0.00) 51 (0.01)
Brain oedema 77 (0.42) 51 (0.20) 11 (0.02) 0 39 (0.05) 48 (0.01) 255 (0.05)
Brain stem infarction 12 (0.07) 25 (0.10) 11 (0.02) 0 64 (0.07) 9 (0.00) 125 (0.02)
Breast cancer 0 12 (0.05) 7 (0.01) 0 11 (0.01) 109 (0.03) 141 (0.03)
Breast discomfort 0 0 8 (0.02) 0 7 (0.01) 37 (0.01) 52 (0.01)
Breast enlargement 0 4 (0.02) 6 (0.01) 0 4 (0.00) 41 (0.01) 55 (0.01)
Breast mass 0 7 (0.03) 13 (0.03) 1 (0.22) 17 (0.02) 136 (0.04) 177 (0.03)
Breast pain 1 (0.01) 23 (0.09) 120 (0.25) 2 (0.43) 147 (0.17) 888 (0.26) 1189 (0.23)
Breast swelling 0 3 (0.01) 28 (0.06) 0 16 (0.02) 187 (0.06) 235 (0.05)
Breast tenderness 0 3 (0.01) 15 (0.03) 0 7 (0.01) 105 (0.03) 130 (0.03)
Breath sounds abnormal 8 (0.04) 5 (0.02) 2 (0.00) 0 16 (0.02) 22 (0.01) 59 (0.01)
Bronchitis 14 (0.08) 11 (0.04) 18 (0.04) 0 72 (0.08) 111 (0.03) 235 (0.05)
Bronchospasm 6 (0.03) 74 (0.29) 6 (0.01) 0 121 (0.14) 214 (0.06) 441 (0.09)
Bruxism 0 1 (0.00) 7 (0.01) 0 10 (0.01) 35 (0.01) 53 (0.01)
Bundle branch block left 4 (0.02) 8 (0.03) 5 (0.01) 0 23 (0.03) 12 (0.00) 55 (0.01)
Bundle branch block right 2 (0.01) 17 (0.07) 3 (0.01) 0 28 (0.03) 19 (0.01) 74 (0.01)
Burning sensation 5 (0.03) 112 (0.44) 413 (0.84) 4 (0.87) 271 (0.32) 1313 (0.39) 2157 (0.42)
Bursitis 0 5 (0.02) 123 (0.25) 0 30 (0.03) 210 (0.06) 371 (0.07)
C-reactive protein increased 34 (0.19) 41 (0.16) 53 (0.11) 0 389 (0.45) 171 (0.05) 738 (0.14)
COVID-19 1411 (7.74) 382 (1.51) 259 (0.53) 3 (0.65) 4036 (4.70) 20998 (6.25) 27373 (5.32)
COVID-19 immunisation 4 (0.02) 24 (0.09) 83 (0.17) 0 73 (0.09) 173 (0.05) 358 (0.07)
COVID-19 pneumonia 442 (2.42) 147 (0.58) 27 (0.06) 0 874 (1.02) 154 (0.05) 1683 (0.33)
CSF protein increased 0 11 (0.04) 12 (0.02) 0 55 (0.06) 1 (0.00) 91 (0.02)
Candida infection 2 (0.01) 4 (0.02) 11 (0.02) 0 7 (0.01) 70 (0.02) 95 (0.02)
Capillary leak syndrome 10 (0.05) 16 (0.06) 2 (0.00) 0 18 (0.02) 25 (0.01) 74 (0.01)
Cardiac arrest 1102 (6.04) 365 (1.44) 7 (0.01) 0 103 (0.12) 90 (0.03) 1771 (0.34)
Cardiac death 62 (0.34) 1 (0.00) 0 0 1 (0.00) 0 64 (0.01)
Cardiac discomfort 2 (0.01) 23 (0.09) 23 (0.05) 0 63 (0.07) 87 (0.03) 202 (0.04)
Cardiac disorder 68 (0.37) 92 (0.36) 41 (0.08) 0 192 (0.22) 164 (0.05) 582 (0.11)
Cardiac dysfunction 4 (0.02) 17 (0.07) 4 (0.01) 1 (0.22) 20 (0.02) 18 (0.01) 74 (0.01)
Cardiac failure 393 (2.16) 247 (0.97) 56 (0.11) 0 482 (0.56) 178 (0.05) 1425 (0.28)
Cardiac failure acute 134 (0.73) 33 (0.13) 0 0 69 (0.08) 9 (0.00) 248 (0.05)
Cardiac failure chronic 18 (0.10) 6 (0.02) 1 (0.00) 0 25 (0.03) 8 (0.00) 64 (0.01)
Cardiac failure congestive 89 (0.49) 63 (0.25) 17 (0.03) 0 158 (0.18) 53 (0.02) 397 (0.08)
Cardiac fibrillation 1 (0.01) 19 (0.07) 10 (0.02) 1 (0.22) 38 (0.04) 48 (0.01) 124 (0.02)
Cardiac flutter 2 (0.01) 24 (0.09) 62 (0.13) 0 78 (0.09) 1118 (0.33) 1296 (0.25)
Cardiac murmur 3 (0.02) 5 (0.02) 11 (0.02) 2 (0.43) 21 (0.02) 44 (0.01) 87 (0.02)
Cardiac tamponade 29 (0.16) 32 (0.13) 0 0 25 (0.03) 7 (0.00) 97 (0.02)
Cardiac ventricular thrombosis 7 (0.04) 26 (0.10) 2 (0.00) 0 16 (0.02) 4 (0.00) 59 (0.01)
Cardio-respiratory arrest 553 (3.03) 102 (0.40) 0 0 27 (0.03) 13 (0.00) 747 (0.15)
Cardiogenic shock 105 (0.58) 58 (0.23) 1 (0.00) 0 23 (0.03) 13 (0.00) 214 (0.04)
Cardiomegaly 35 (0.19) 45 (0.18) 19 (0.04) 1 (0.22) 98 (0.11) 35 (0.01) 250 (0.05)
Cardiomyopathy 21 (0.12) 49 (0.19) 11 (0.02) 0 75 (0.09) 57 (0.02) 226 (0.04)
Cardiovascular disorder 59 (0.32) 43 (0.17) 102 (0.21) 0 177 (0.21) 145 (0.04) 538 (0.10)
Cardiovascular insufficiency 6 (0.03) 4 (0.02) 2 (0.00) 0 8 (0.01) 29 (0.01) 52 (0.01)
Carditis 4 (0.02) 2 (0.01) 4 (0.01) 0 21 (0.02) 39 (0.01) 74 (0.01)
Carotid artery dissection 3 (0.02) 20 (0.08) 1 (0.00) 0 26 (0.03) 4 (0.00) 55 (0.01)
Carotid artery occlusion 10 (0.05) 20 (0.08) 7 (0.01) 0 30 (0.03) 10 (0.00) 81 (0.02)
Carotid artery stenosis 5 (0.03) 8 (0.03) 5 (0.01) 0 33 (0.04) 6 (0.00) 59 (0.01)
Carotid artery thrombosis 14 (0.08) 31 (0.12) 12 (0.02) 0 24 (0.03) 7 (0.00) 91 (0.02)
Carpal tunnel syndrome 0 1 (0.00) 29 (0.06) 0 9 (0.01) 63 (0.02) 103 (0.02)
Cataract 0 0 19 (0.04) 0 12 (0.01) 69 (0.02) 102 (0.02)
Catarrh 0 4 (0.02) 12 (0.02) 0 4 (0.00) 50 (0.01) 71 (0.01)
Cellulitis 15 (0.08) 32 (0.13) 57 (0.12) 0 215 (0.25) 1678 (0.50) 2030 (0.39)
Central nervous system lesion 3 (0.02) 4 (0.02) 12 (0.02) 0 32 (0.04) 12 (0.00) 69 (0.01)
Cerebellar haemorrhage 11 (0.06) 14 (0.06) 4 (0.01) 0 21 (0.02) 7 (0.00) 62 (0.01)
Cerebellar infarction 8 (0.04) 33 (0.13) 12 (0.02) 0 64 (0.07) 14 (0.00) 135 (0.03)
Cerebellar stroke 5 (0.03) 26 (0.10) 8 (0.02) 0 53 (0.06) 14 (0.00) 107 (0.02)
Cerebral artery embolism 17 (0.09) 33 (0.13) 11 (0.02) 1 (0.22) 18 (0.02) 11 (0.00) 91 (0.02)
Cerebral artery occlusion 12 (0.07) 22 (0.09) 12 (0.02) 0 42 (0.05) 4 (0.00) 96 (0.02)
Cerebral artery thrombosis 14 (0.08) 31 (0.12) 10 (0.02) 0 25 (0.03) 9 (0.00) 92 (0.02)
Cerebral disorder 5 (0.03) 4 (0.02) 9 (0.02) 0 14 (0.02) 13 (0.00) 52 (0.01)
Cerebral haematoma 21 (0.12) 28 (0.11) 2 (0.00) 0 36 (0.04) 2 (0.00) 104 (0.02)
Cerebral haemorrhage 510 (2.80) 346 (1.37) 86 (0.18) 0 415 (0.48) 115 (0.03) 1533 (0.30)
Cerebral infarction 153 (0.84) 361 (1.42) 208 (0.43) 0 929 (1.08) 176 (0.05) 1890 (0.37)
Cerebral ischaemia 23 (0.13) 41 (0.16) 24 (0.05) 0 100 (0.12) 41 (0.01) 240 (0.05)
Cerebral small vessel ischaemic disease 6 (0.03) 4 (0.02) 11 (0.02) 0 31 (0.04) 6 (0.00) 63 (0.01)
Cerebral thrombosis 84 (0.46) 129 (0.51) 31 (0.06) 0 217 (0.25) 86 (0.03) 572 (0.11)
Cerebral venous sinus thrombosis 149 (0.82) 381 (1.50) 34 (0.07) 0 436 (0.51) 119 (0.04) 1143 (0.22)
Cerebral venous thrombosis 59 (0.32) 112 (0.44) 12 (0.02) 0 165 (0.19) 51 (0.02) 416 (0.08)
Cerebrovascular accident 556 (3.05) 1388 (5.48) 675 (1.38) 5 (1.09) 2419 (2.82) 1295 (0.39) 6527 (1.27)
Cerebrovascular disorder 13 (0.07) 11 (0.04) 4 (0.01) 0 32 (0.04) 13 (0.00) 75 (0.01)
Cheilitis 0 5 (0.02) 5 (0.01) 0 8 (0.01) 37 (0.01) 56 (0.01)
Chest X-ray 3 (0.02) 34 (0.13) 10 (0.02) 0 40 (0.05) 37 (0.01) 124 (0.02)
Chest X-ray abnormal 12 (0.07) 23 (0.09) 3 (0.01) 0 59 (0.07) 8 (0.00) 107 (0.02)
Chest discomfort 61 (0.33) 456 (1.80) 665 (1.36) 4 (0.87) 1849 (2.15) 3530 (1.05) 6689 (1.30)
Chest pain 290 (1.59) 1460 (5.76) 1649 (3.37) 4 (0.87) 4914 (5.72) 7866 (2.34) 16510 (3.21)
Chillblains 0 1 (0.00) 7 (0.01) 0 2 (0.00) 70 (0.02) 80 (0.02)
Chills 206 (1.13) 887 (3.50) 9084 (18.58) 14 (3.04) 3417 (3.98) 39904 (11.87) 53725 (10.44)
Choking 15 (0.08) 26 (0.10) 6 (0.01) 0 22 (0.03) 136 (0.04) 221 (0.04)
Choking sensation 1 (0.01) 19 (0.07) 10 (0.02) 0 27 (0.03) 53 (0.02) 116 (0.02)
Cholecystitis 4 (0.02) 5 (0.02) 6 (0.01) 0 59 (0.07) 23 (0.01) 105 (0.02)
Cholecystitis acute 3 (0.02) 6 (0.02) 2 (0.00) 0 31 (0.04) 6 (0.00) 51 (0.01)
Cholelithiasis 5 (0.03) 8 (0.03) 6 (0.01) 0 57 (0.07) 20 (0.01) 102 (0.02)
Cholestasis 3 (0.02) 1 (0.00) 2 (0.00) 0 29 (0.03) 16 (0.00) 53 (0.01)
Chromaturia 4 (0.02) 24 (0.09) 23 (0.05) 0 68 (0.08) 125 (0.04) 250 (0.05)
Chronic fatigue syndrome 0 3 (0.01) 123 (0.25) 0 23 (0.03) 123 (0.04) 275 (0.05)
Chronic inflammatory demyelinating polyradiculoneuropathy 0 3 (0.01) 27 (0.06) 0 31 (0.04) 20 (0.01) 86 (0.02)
Chronic kidney disease 23 (0.13) 10 (0.04) 4 (0.01) 0 50 (0.06) 27 (0.01) 121 (0.02)
Chronic obstructive pulmonary disease 68 (0.37) 33 (0.13) 13 (0.03) 0 139 (0.16) 57 (0.02) 326 (0.06)
Circulatory collapse 153 (0.84) 113 (0.45) 23 (0.05) 0 241 (0.28) 420 (0.12) 1017 (0.20)
Clumsiness 0 3 (0.01) 27 (0.06) 0 12 (0.01) 43 (0.01) 87 (0.02)
Cluster headache 3 (0.02) 14 (0.06) 128 (0.26) 0 39 (0.05) 638 (0.19) 822 (0.16)
Coagulopathy 48 (0.26) 83 (0.33) 63 (0.13) 1 (0.22) 113 (0.13) 125 (0.04) 449 (0.09)
Cognitive disorder 22 (0.12) 36 (0.14) 218 (0.45) 0 101 (0.12) 245 (0.07) 646 (0.13)
Cold sweat 31 (0.17) 114 (0.45) 294 (0.60) 1 (0.22) 340 (0.40) 1933 (0.58) 2755 (0.54)
Cold-stimulus headache 0 6 (0.02) 16 (0.03) 0 4 (0.00) 72 (0.02) 98 (0.02)
Colitis 6 (0.03) 24 (0.09) 19 (0.04) 0 119 (0.14) 99 (0.03) 268 (0.05)
Colitis ischaemic 11 (0.06) 15 (0.06) 1 (0.00) 0 81 (0.09) 41 (0.01) 152 (0.03)
Colitis ulcerative 0 15 (0.06) 42 (0.09) 0 73 (0.09) 267 (0.08) 401 (0.08)
Coma 86 (0.47) 89 (0.35) 11 (0.02) 0 59 (0.07) 27 (0.01) 325 (0.06)
Coma scale abnormal 17 (0.09) 14 (0.06) 3 (0.01) 0 13 (0.02) 11 (0.00) 71 (0.01)
Communication disorder 9 (0.05) 14 (0.06) 5 (0.01) 0 28 (0.03) 10 (0.00) 80 (0.02)
Complex regional pain syndrome 0 1 (0.00) 20 (0.04) 0 7 (0.01) 25 (0.01) 54 (0.01)
Computerised tomogram 9 (0.05) 84 (0.33) 24 (0.05) 1 (0.22) 72 (0.08) 62 (0.02) 252 (0.05)
Computerised tomogram abnormal 4 (0.02) 27 (0.11) 2 (0.00) 0 26 (0.03) 22 (0.01) 82 (0.02)
Computerised tomogram head 1 (0.01) 25 (0.10) 6 (0.01) 1 (0.22) 44 (0.05) 28 (0.01) 106 (0.02)
Computerised tomogram head abnormal 19 (0.10) 44 (0.17) 13 (0.03) 0 53 (0.06) 2 (0.00) 131 (0.03)
Computerised tomogram head normal 2 (0.01) 13 (0.05) 13 (0.03) 0 32 (0.04) 3 (0.00) 63 (0.01)
Computerised tomogram thorax 3 (0.02) 23 (0.09) 1 (0.00) 0 31 (0.04) 26 (0.01) 84 (0.02)
Computerised tomogram thorax abnormal 8 (0.04) 98 (0.39) 5 (0.01) 0 57 (0.07) 5 (0.00) 173 (0.03)
Concomitant disease aggravated 17 (0.09) 1 (0.00) 15 (0.03) 0 24 (0.03) 27 (0.01) 91 (0.02)
Concussion 1 (0.01) 10 (0.04) 13 (0.03) 0 39 (0.05) 27 (0.01) 95 (0.02)
Condition aggravated 232 (1.27) 262 (1.03) 726 (1.49) 2 (0.43) 912 (1.06) 1690 (0.50) 3931 (0.76)
Confusional state 161 (0.88) 374 (1.48) 738 (1.51) 1 (0.22) 1087 (1.27) 2124 (0.63) 4613 (0.90)
Congestive cardiomyopathy 15 (0.08) 20 (0.08) 5 (0.01) 0 36 (0.04) 14 (0.00) 99 (0.02)
Conjunctival haemorrhage 2 (0.01) 6 (0.02) 12 (0.02) 0 19 (0.02) 286 (0.09) 329 (0.06)
Conjunctival hyperaemia 2 (0.01) 5 (0.02) 2 (0.00) 0 27 (0.03) 40 (0.01) 77 (0.01)
Conjunctivitis 2 (0.01) 7 (0.03) 23 (0.05) 1 (0.22) 34 (0.04) 130 (0.04) 197 (0.04)
Constipation 11 (0.06) 31 (0.12) 138 (0.28) 0 156 (0.18) 449 (0.13) 800 (0.16)
Contusion 35 (0.19) 193 (0.76) 356 (0.73) 1 (0.22) 424 (0.49) 2325 (0.69) 3384 (0.66)
Conversion disorder 0 2 (0.01) 33 (0.07) 0 36 (0.04) 24 (0.01) 97 (0.02)
Coordination abnormal 11 (0.06) 23 (0.09) 86 (0.18) 1 (0.22) 92 (0.11) 142 (0.04) 365 (0.07)
Coronary artery disease 50 (0.27) 36 (0.14) 6 (0.01) 1 (0.22) 75 (0.09) 10 (0.00) 192 (0.04)
Coronary artery occlusion 16 (0.09) 59 (0.23) 4 (0.01) 0 43 (0.05) 9 (0.00) 140 (0.03)
Coronary artery stenosis 10 (0.05) 22 (0.09) 2 (0.00) 1 (0.22) 25 (0.03) 9 (0.00) 73 (0.01)
Coronary artery thrombosis 35 (0.19) 71 (0.28) 2 (0.00) 0 26 (0.03) 9 (0.00) 156 (0.03)
Costochondritis 0 2 (0.01) 41 (0.08) 0 34 (0.04) 116 (0.03) 195 (0.04)
Cough 464 (2.54) 486 (1.92) 965 (1.97) 2 (0.43) 2338 (2.72) 5307 (1.58) 9743 (1.89)
Craniocerebral injury 10 (0.05) 3 (0.01) 6 (0.01) 0 21 (0.02) 18 (0.01) 61 (0.01)
Crohn's disease 0 5 (0.02) 41 (0.08) 0 42 (0.05) 173 (0.05) 268 (0.05)
Crying 1 (0.01) 18 (0.07) 87 (0.18) 0 46 (0.05) 347 (0.10) 502 (0.10)
Cutaneous vasculitis 2 (0.01) 2 (0.01) 3 (0.01) 0 94 (0.11) 121 (0.04) 226 (0.04)
Cyanosis 78 (0.43) 73 (0.29) 46 (0.09) 0 184 (0.21) 192 (0.06) 616 (0.12)
Cyst 0 4 (0.02) 12 (0.02) 1 (0.22) 14 (0.02) 45 (0.01) 78 (0.02)
Cystitis 4 (0.02) 8 (0.03) 22 (0.05) 0 55 (0.06) 173 (0.05) 267 (0.05)
Deafness 2 (0.01) 23 (0.09) 362 (0.74) 0 97 (0.11) 1109 (0.33) 1627 (0.32)
Deafness bilateral 0 0 39 (0.08) 0 4 (0.00) 54 (0.02) 98 (0.02)
Deafness neurosensory 1 (0.01) 4 (0.02) 117 (0.24) 0 14 (0.02) 137 (0.04) 279 (0.05)
Deafness unilateral 0 5 (0.02) 260 (0.53) 0 46 (0.05) 471 (0.14) 797 (0.15)
Death 4901 (26.88) 4 (0.02) 0 0 1 (0.00) 3 (0.00) 4910 (0.95)
Decreased activity 5 (0.03) 2 (0.01) 17 (0.03) 0 10 (0.01) 23 (0.01) 61 (0.01)
Decreased appetite 272 (1.49) 211 (0.83) 1322 (2.70) 2 (0.43) 1025 (1.19) 6201 (1.85) 9179 (1.78)
Deep vein thrombosis 153 (0.84) 1341 (5.29) 187 (0.38) 2 (0.43) 2282 (2.66) 4026 (1.20) 8193 (1.59)
Dehydration 57 (0.31) 87 (0.34) 128 (0.26) 0 462 (0.54) 691 (0.21) 1479 (0.29)
Delirium 32 (0.18) 62 (0.24) 113 (0.23) 0 156 (0.18) 652 (0.19) 1063 (0.21)
Delusion 4 (0.02) 9 (0.04) 23 (0.05) 0 32 (0.04) 52 (0.02) 124 (0.02)
Dementia 26 (0.14) 14 (0.06) 33 (0.07) 0 44 (0.05) 99 (0.03) 250 (0.05)
Demyelinating polyneuropathy 1 (0.01) 12 (0.05) 13 (0.03) 0 37 (0.04) 9 (0.00) 75 (0.01)
Demyelination 2 (0.01) 7 (0.03) 51 (0.10) 0 64 (0.07) 50 (0.01) 185 (0.04)
Depressed level of consciousness 112 (0.61) 122 (0.48) 35 (0.07) 0 327 (0.38) 688 (0.20) 1419 (0.28)
Depressed mood 3 (0.02) 22 (0.09) 177 (0.36) 1 (0.22) 40 (0.05) 798 (0.24) 1047 (0.20)
Depression 7 (0.04) 69 (0.27) 272 (0.56) 1 (0.22) 115 (0.13) 743 (0.22) 1224 (0.24)
Dermatitis 1 (0.01) 8 (0.03) 38 (0.08) 0 27 (0.03) 233 (0.07) 310 (0.06)
Dermatitis allergic 0 21 (0.08) 44 (0.09) 0 54 (0.06) 377 (0.11) 502 (0.10)
Dermatitis atopic 0 0 15 (0.03) 0 10 (0.01) 64 (0.02) 89 (0.02)
Dermatitis bullous 3 (0.02) 3 (0.01) 12 (0.02) 0 27 (0.03) 122 (0.04) 168 (0.03)
Dermatitis contact 0 3 (0.01) 6 (0.01) 0 2 (0.00) 40 (0.01) 51 (0.01)
Dermatomyositis 0 10 (0.04) 8 (0.02) 0 24 (0.03) 18 (0.01) 61 (0.01)
Diabetes mellitus 24 (0.13) 37 (0.15) 36 (0.07) 0 75 (0.09) 240 (0.07) 431 (0.08)
Diabetes mellitus inadequate control 6 (0.03) 6 (0.02) 5 (0.01) 0 19 (0.02) 127 (0.04) 168 (0.03)
Diabetic ketoacidosis 15 (0.08) 43 (0.17) 6 (0.01) 0 59 (0.07) 31 (0.01) 165 (0.03)
Diarrhoea 243 (1.33) 406 (1.60) 1897 (3.88) 4 (0.87) 1987 (2.31) 10556 (3.14) 15273 (2.97)
Diarrhoea haemorrhagic 3 (0.02) 15 (0.06) 7 (0.01) 0 42 (0.05) 156 (0.05) 228 (0.04)
Diplegia 4 (0.02) 19 (0.07) 50 (0.10) 0 46 (0.05) 97 (0.03) 227 (0.04)
Diplopia 3 (0.02) 63 (0.25) 249 (0.51) 0 367 (0.43) 445 (0.13) 1150 (0.22)
Disability 2 (0.01) 7 (0.03) 44 (0.09) 0 8 (0.01) 19 (0.01) 83 (0.02)
Discomfort 31 (0.17) 59 (0.23) 233 (0.48) 1 (0.22) 254 (0.30) 988 (0.29) 1596 (0.31)
Disease progression 10 (0.05) 2 (0.01) 8 (0.02) 0 10 (0.01) 24 (0.01) 56 (0.01)
Disease recurrence 18 (0.10) 67 (0.26) 120 (0.25) 0 179 (0.21) 880 (0.26) 1293 (0.25)
Disorganised speech 1 (0.01) 5 (0.02) 7 (0.01) 1 (0.22) 20 (0.02) 29 (0.01) 65 (0.01)
Disorientation 33 (0.18) 77 (0.30) 214 (0.44) 0 299 (0.35) 828 (0.25) 1483 (0.29)
Disseminated intravascular coagulation 63 (0.35) 59 (0.23) 1 (0.00) 0 33 (0.04) 10 (0.00) 184 (0.04)
Dissociation 0 5 (0.02) 17 (0.03) 0 11 (0.01) 71 (0.02) 106 (0.02)
Disturbance in attention 11 (0.06) 67 (0.26) 458 (0.94) 1 (0.22) 342 (0.40) 1105 (0.33) 2015 (0.39)
Diverticulitis 5 (0.03) 7 (0.03) 10 (0.02) 0 99 (0.12) 130 (0.04) 257 (0.05)
Dizziness 208 (1.14) 1298 (5.12) 4905 (10.03) 10 (2.17) 5782 (6.73) 24460 (7.28) 37002 (7.19)
Dizziness exertional 0 3 (0.01) 25 (0.05) 0 6 (0.01) 119 (0.04) 155 (0.03)
Dizziness postural 1 (0.01) 15 (0.06) 298 (0.61) 0 105 (0.12) 1987 (0.59) 2409 (0.47)
Drooling 5 (0.03) 4 (0.02) 14 (0.03) 0 26 (0.03) 34 (0.01) 88 (0.02)
Drug eruption 0 3 (0.01) 7 (0.01) 0 39 (0.05) 98 (0.03) 148 (0.03)
Drug hypersensitivity 1 (0.01) 22 (0.09) 14 (0.03) 0 37 (0.04) 120 (0.04) 201 (0.04)
Drug ineffective 243 (1.33) 121 (0.48) 85 (0.17) 0 550 (0.64) 5891 (1.75) 7108 (1.38)
Drug interaction 6 (0.03) 9 (0.04) 8 (0.02) 0 39 (0.05) 79 (0.02) 143 (0.03)
Drug reaction with eosinophilia and systemic symptoms 1 (0.01) 11 (0.04) 5 (0.01) 0 30 (0.03) 15 (0.00) 62 (0.01)
Dry eye 0 4 (0.02) 89 (0.18) 0 32 (0.04) 296 (0.09) 424 (0.08)
Dry mouth 1 (0.01) 52 (0.21) 189 (0.39) 0 153 (0.18) 1060 (0.32) 1468 (0.29)
Dry skin 0 7 (0.03) 56 (0.11) 0 21 (0.02) 353 (0.11) 441 (0.09)
Dry throat 1 (0.01) 14 (0.06) 45 (0.09) 0 24 (0.03) 267 (0.08) 354 (0.07)
Dysaesthesia 0 10 (0.04) 29 (0.06) 0 96 (0.11) 150 (0.04) 294 (0.06)
Dysarthria 63 (0.35) 198 (0.78) 220 (0.45) 0 620 (0.72) 433 (0.13) 1602 (0.31)
Dysentery 0 6 (0.02) 18 (0.04) 0 12 (0.01) 143 (0.04) 179 (0.03)
Dysgeusia 6 (0.03) 47 (0.19) 256 (0.52) 1 (0.22) 141 (0.16) 1610 (0.48) 2077 (0.40)
Dysgraphia 0 7 (0.03) 14 (0.03) 0 12 (0.01) 16 (0.00) 53 (0.01)
Dyskinesia 6 (0.03) 21 (0.08) 86 (0.18) 1 (0.22) 147 (0.17) 190 (0.06) 467 (0.09)
Dyslalia 0 3 (0.01) 9 (0.02) 0 51 (0.06) 6 (0.00) 82 (0.02)
Dysmenorrhoea 0 15 (0.06) 383 (0.78) 2 (0.43) 87 (0.10) 3327 (0.99) 3825 (0.74)
Dyspepsia 14 (0.08) 54 (0.21) 176 (0.36) 0 113 (0.13) 871 (0.26) 1242 (0.24)
Dysphagia 70 (0.38) 224 (0.88) 191 (0.39) 2 (0.43) 467 (0.54) 696 (0.21) 1733 (0.34)
Dysphemia 2 (0.01) 11 (0.04) 18 (0.04) 0 30 (0.03) 38 (0.01) 102 (0.02)
Dysphonia 8 (0.04) 94 (0.37) 107 (0.22) 0 221 (0.26) 449 (0.13) 912 (0.18)
Dysphoria 3 (0.02) 8 (0.03) 0 0 64 (0.07) 116 (0.03) 199 (0.04)
Dyspnoea 1420 (7.79) 2954 (11.65) 2550 (5.22) 7 (1.52) 8122 (9.46) 11476 (3.41) 27363 (5.31)
Dyspnoea at rest 3 (0.02) 8 (0.03) 11 (0.02) 0 41 (0.05) 93 (0.03) 162 (0.03)
Dyspnoea exertional 32 (0.18) 129 (0.51) 105 (0.21) 0 391 (0.46) 335 (0.10) 1047 (0.20)
Dysstasia 13 (0.07) 68 (0.27) 207 (0.42) 0 250 (0.29) 299 (0.09) 877 (0.17)
Dystonia 1 (0.01) 5 (0.02) 13 (0.03) 0 15 (0.02) 60 (0.02) 99 (0.02)
Dysuria 10 (0.05) 20 (0.08) 41 (0.08) 0 101 (0.12) 160 (0.05) 339 (0.07)
Ear congestion 0 4 (0.02) 25 (0.05) 0 5 (0.01) 44 (0.01) 78 (0.02)
Ear discomfort 0 15 (0.06) 162 (0.33) 0 80 (0.09) 275 (0.08) 548 (0.11)
Ear disorder 0 2 (0.01) 25 (0.05) 0 7 (0.01) 38 (0.01) 74 (0.01)
Ear infection 1 (0.01) 7 (0.03) 42 (0.09) 0 19 (0.02) 210 (0.06) 286 (0.06)
Ear pain 3 (0.02) 33 (0.13) 478 (0.98) 1 (0.22) 180 (0.21) 2176 (0.65) 2893 (0.56)
Ear swelling 0 8 (0.03) 11 (0.02) 0 23 (0.03) 96 (0.03) 141 (0.03)
Eating disorder 7 (0.04) 8 (0.03) 23 (0.05) 0 44 (0.05) 56 (0.02) 149 (0.03)
Ecchymosis 2 (0.01) 22 (0.09) 9 (0.02) 0 93 (0.11) 111 (0.03) 250 (0.05)
Echocardiogram 5 (0.03) 62 (0.24) 6 (0.01) 1 (0.22) 60 (0.07) 10 (0.00) 144 (0.03)
Echocardiogram abnormal 6 (0.03) 20 (0.08) 2 (0.00) 1 (0.22) 25 (0.03) 6 (0.00) 61 (0.01)
Ectopic pregnancy 0 16 (0.06) 3 (0.01) 2 (0.43) 11 (0.01) 21 (0.01) 54 (0.01)
Eczema 1 (0.01) 7 (0.03) 72 (0.15) 0 66 (0.08) 451 (0.13) 603 (0.12)
Ejection fraction decreased 10 (0.05) 19 (0.07) 7 (0.01) 0 38 (0.04) 10 (0.00) 96 (0.02)
Electric shock sensation 1 (0.01) 16 (0.06) 81 (0.17) 0 30 (0.03) 128 (0.04) 259 (0.05)
Electrocardiogram 3 (0.02) 62 (0.24) 12 (0.02) 0 44 (0.05) 59 (0.02) 180 (0.03)
Electrocardiogram ST segment elevation 1 (0.01) 14 (0.06) 2 (0.00) 0 78 (0.09) 56 (0.02) 167 (0.03)
Electrocardiogram abnormal 3 (0.02) 34 (0.13) 8 (0.02) 0 98 (0.11) 55 (0.02) 209 (0.04)
Electrocardiogram normal 1 (0.01) 14 (0.06) 5 (0.01) 0 23 (0.03) 12 (0.00) 55 (0.01)
Embolic stroke 12 (0.07) 36 (0.14) 22 (0.05) 0 63 (0.07) 19 (0.01) 159 (0.03)
Embolism 56 (0.31) 143 (0.56) 53 (0.11) 0 157 (0.18) 182 (0.05) 609 (0.12)
Embolism arterial 5 (0.03) 15 (0.06) 4 (0.01) 0 20 (0.02) 8 (0.00) 52 (0.01)
Embolism venous 7 (0.04) 17 (0.07) 3 (0.01) 0 40 (0.05) 22 (0.01) 90 (0.02)
Emotional disorder 0 3 (0.01) 32 (0.07) 0 8 (0.01) 141 (0.04) 184 (0.04)
Emotional distress 1 (0.01) 20 (0.08) 53 (0.11) 0 26 (0.03) 118 (0.04) 223 (0.04)
Emphysema 15 (0.08) 7 (0.03) 4 (0.01) 0 24 (0.03) 9 (0.00) 61 (0.01)
Encephalitis 16 (0.09) 85 (0.34) 30 (0.06) 0 208 (0.24) 68 (0.02) 422 (0.08)
Encephalitis autoimmune 3 (0.02) 13 (0.05) 5 (0.01) 0 33 (0.04) 2 (0.00) 59 (0.01)
Encephalopathy 28 (0.15) 32 (0.13) 17 (0.03) 0 121 (0.14) 36 (0.01) 255 (0.05)
Endocarditis 10 (0.05) 20 (0.08) 2 (0.00) 0 34 (0.04) 18 (0.01) 91 (0.02)
Endometriosis 0 1 (0.00) 26 (0.05) 0 16 (0.02) 132 (0.04) 176 (0.03)
Endotracheal intubation 52 (0.29) 43 (0.17) 1 (0.00) 0 37 (0.04) 0 139 (0.03)
Enlarged uvula 0 9 (0.04) 1 (0.00) 0 13 (0.02) 31 (0.01) 55 (0.01)
Enteritis 2 (0.01) 6 (0.02) 3 (0.01) 0 28 (0.03) 11 (0.00) 52 (0.01)
Enterocolitis 2 (0.01) 4 (0.02) 3 (0.01) 0 15 (0.02) 24 (0.01) 51 (0.01)
Enuresis 1 (0.01) 5 (0.02) 14 (0.03) 0 9 (0.01) 54 (0.02) 83 (0.02)
Eosinophilia 2 (0.01) 9 (0.04) 7 (0.01) 0 39 (0.05) 28 (0.01) 92 (0.02)
Epididymitis 0 0 6 (0.01) 0 9 (0.01) 43 (0.01) 58 (0.01)
Epigastric discomfort 2 (0.01) 5 (0.02) 5 (0.01) 0 21 (0.02) 31 (0.01) 65 (0.01)
Epilepsy 30 (0.16) 154 (0.61) 80 (0.16) 0 522 (0.61) 686 (0.20) 1497 (0.29)
Epistaxis 34 (0.19) 167 (0.66) 209 (0.43) 2 (0.43) 407 (0.47) 1714 (0.51) 2560 (0.50)
Epstein-Barr virus infection reactivation 0 1 (0.00) 5 (0.01) 0 14 (0.02) 34 (0.01) 57 (0.01)
Erectile dysfunction 1 (0.01) 8 (0.03) 62 (0.13) 0 15 (0.02) 230 (0.07) 319 (0.06)
Eructation 1 (0.01) 8 (0.03) 33 (0.07) 0 25 (0.03) 103 (0.03) 174 (0.03)
Erysipelas 3 (0.02) 8 (0.03) 11 (0.02) 0 69 (0.08) 165 (0.05) 261 (0.05)
Erythema 28 (0.15) 263 (1.04) 389 (0.80) 4 (0.87) 1037 (1.21) 4230 (1.26) 6044 (1.17)
Erythema multiforme 1 (0.01) 7 (0.03) 6 (0.01) 0 76 (0.09) 369 (0.11) 463 (0.09)
Erythema nodosum 0 2 (0.01) 12 (0.02) 0 27 (0.03) 85 (0.03) 127 (0.02)
Erythema of eyelid 0 2 (0.01) 5 (0.01) 0 11 (0.01) 48 (0.01) 66 (0.01)
Euphoric mood 0 5 (0.02) 10 (0.02) 0 7 (0.01) 77 (0.02) 99 (0.02)
Exercise tolerance decreased 1 (0.01) 23 (0.09) 98 (0.20) 0 80 (0.09) 102 (0.03) 326 (0.06)
Exposure during pregnancy 5 (0.03) 25 (0.10) 7 (0.01) 20 (4.35) 105 (0.12) 168 (0.05) 341 (0.07)
Exposure to SARS-CoV-2 11 (0.06) 2 (0.01) 4 (0.01) 0 54 (0.06) 26 (0.01) 100 (0.02)
Exposure via breast milk 2 (0.01) 3 (0.01) 9 (0.02) 2 (0.43) 13 (0.02) 215 (0.06) 245 (0.05)
Extensive swelling of vaccinated limb 1 (0.01) 16 (0.06) 552 (1.13) 0 26 (0.03) 136 (0.04) 732 (0.14)
Extrasystoles 4 (0.02) 43 (0.17) 81 (0.17) 1 (0.22) 120 (0.14) 348 (0.10) 605 (0.12)
Eye discharge 1 (0.01) 1 (0.00) 14 (0.03) 1 (0.22) 3 (0.00) 39 (0.01) 60 (0.01)
Eye disorder 2 (0.01) 7 (0.03) 51 (0.10) 0 64 (0.07) 131 (0.04) 257 (0.05)
Eye haemorrhage 1 (0.01) 8 (0.03) 40 (0.08) 0 33 (0.04) 390 (0.12) 486 (0.09)
Eye infection 0 2 (0.01) 14 (0.03) 1 (0.22) 12 (0.01) 51 (0.02) 81 (0.02)
Eye inflammation 1 (0.01) 3 (0.01) 21 (0.04) 0 25 (0.03) 58 (0.02) 112 (0.02)
Eye injury 1 (0.01) 7 (0.03) 29 (0.06) 0 13 (0.02) 43 (0.01) 93 (0.02)
Eye irritation 0 14 (0.06) 74 (0.15) 0 30 (0.03) 270 (0.08) 393 (0.08)
Eye movement disorder 4 (0.02) 23 (0.09) 44 (0.09) 0 70 (0.08) 92 (0.03) 247 (0.05)
Eye oedema 1 (0.01) 5 (0.02) 13 (0.03) 0 8 (0.01) 53 (0.02) 82 (0.02)
Eye pain 2 (0.01) 81 (0.32) 711 (1.45) 0 264 (0.31) 3146 (0.94) 4226 (0.82)
Eye pruritus 0 26 (0.10) 50 (0.10) 0 55 (0.06) 383 (0.11) 523 (0.10)
Eye swelling 0 61 (0.24) 111 (0.23) 1 (0.22) 101 (0.12) 819 (0.24) 1106 (0.21)
Eyelid disorder 0 0 22 (0.05) 0 11 (0.01) 17 (0.01) 53 (0.01)
Eyelid function disorder 0 3 (0.01) 20 (0.04) 0 15 (0.02) 24 (0.01) 64 (0.01)
Eyelid oedema 1 (0.01) 14 (0.06) 15 (0.03) 0 68 (0.08) 187 (0.06) 291 (0.06)
Eyelid ptosis 2 (0.01) 13 (0.05) 45 (0.09) 0 73 (0.09) 117 (0.03) 262 (0.05)
Face injury 1 (0.01) 3 (0.01) 4 (0.01) 0 14 (0.02) 33 (0.01) 56 (0.01)
Face oedema 3 (0.02) 50 (0.20) 27 (0.06) 0 137 (0.16) 345 (0.10) 571 (0.11)
Facial asymmetry 2 (0.01) 2 (0.01) 5 (0.01) 0 34 (0.04) 27 (0.01) 72 (0.01)
Facial bones fracture 0 4 (0.02) 6 (0.01) 0 20 (0.02) 22 (0.01) 54 (0.01)
Facial discomfort 0 4 (0.02) 8 (0.02) 0 11 (0.01) 43 (0.01) 68 (0.01)
Facial pain 0 11 (0.04) 136 (0.28) 0 71 (0.08) 409 (0.12) 633 (0.12)
Facial paralysis 18 (0.10) 145 (0.57) 405 (0.83) 3 (0.65) 1076 (1.25) 2853 (0.85) 4596 (0.89)
Facial paresis 5 (0.03) 59 (0.23) 156 (0.32) 0 463 (0.54) 426 (0.13) 1132 (0.22)
Facial spasm 0 2 (0.01) 24 (0.05) 0 11 (0.01) 54 (0.02) 91 (0.02)
Faeces discoloured 7 (0.04) 12 (0.05) 18 (0.04) 0 44 (0.05) 68 (0.02) 158 (0.03)
Faeces soft 1 (0.01) 1 (0.00) 5 (0.01) 0 14 (0.02) 36 (0.01) 58 (0.01)
Fall 202 (1.11) 230 (0.91) 246 (0.50) 0 1025 (1.19) 814 (0.24) 2700 (0.52)
Fatigue 477 (2.62) 1352 (5.33) 14437 (29.54) 20 (4.35) 5018 (5.84) 51311 (15.27) 73018 (14.18)
Fear 1 (0.01) 22 (0.09) 43 (0.09) 0 31 (0.04) 95 (0.03) 194 (0.04)
Febrile convulsion 5 (0.03) 8 (0.03) 19 (0.04) 1 (0.22) 56 (0.07) 133 (0.04) 224 (0.04)
Feeding disorder 17 (0.09) 36 (0.14) 106 (0.22) 0 105 (0.12) 279 (0.08) 569 (0.11)
Feeling abnormal 67 (0.37) 257 (1.01) 1056 (2.16) 3 (0.65) 940 (1.09) 4387 (1.31) 6829 (1.33)
Feeling cold 17 (0.09) 103 (0.41) 681 (1.39) 1 (0.22) 339 (0.39) 4877 (1.45) 6037 (1.17)
Feeling drunk 1 (0.01) 3 (0.01) 33 (0.07) 1 (0.22) 15 (0.02) 177 (0.05) 231 (0.04)
Feeling hot 17 (0.09) 138 (0.54) 426 (0.87) 2 (0.43) 606 (0.71) 3031 (0.90) 4267 (0.83)
Feeling jittery 0 7 (0.03) 7 (0.01) 0 32 (0.04) 82 (0.02) 134 (0.03)
Feeling of body temperature change 7 (0.04) 17 (0.07) 206 (0.42) 0 94 (0.11) 1055 (0.31) 1382 (0.27)
Feeling of despair 0 3 (0.01) 10 (0.02) 0 5 (0.01) 35 (0.01) 54 (0.01)
Fibrin D dimer 1 (0.01) 22 (0.09) 4 (0.01) 0 33 (0.04) 27 (0.01) 88 (0.02)
Fibrin D dimer increased 53 (0.29) 148 (0.58) 33 (0.07) 0 544 (0.63) 354 (0.11) 1310 (0.25)
Fibromyalgia 1 (0.01) 9 (0.04) 164 (0.34) 0 30 (0.03) 296 (0.09) 505 (0.10)
Fine motor skill dysfunction 2 (0.01) 8 (0.03) 38 (0.08) 0 25 (0.03) 31 (0.01) 108 (0.02)
Flank pain 6 (0.03) 28 (0.11) 48 (0.10) 0 88 (0.10) 131 (0.04) 307 (0.06)
Flatulence 2 (0.01) 13 (0.05) 71 (0.15) 0 37 (0.04) 403 (0.12) 530 (0.10)
Fluid intake reduced 8 (0.04) 4 (0.02) 8 (0.02) 0 24 (0.03) 12 (0.00) 64 (0.01)
Fluid retention 9 (0.05) 19 (0.07) 37 (0.08) 0 48 (0.06) 102 (0.03) 220 (0.04)
Flushing 4 (0.02) 96 (0.38) 111 (0.23) 0 267 (0.31) 968 (0.29) 1465 (0.28)
Foaming at mouth 10 (0.05) 8 (0.03) 1 (0.00) 0 11 (0.01) 10 (0.00) 55 (0.01)
Foetal death 21 (0.12) 6 (0.02) 3 (0.01) 9 (1.96) 45 (0.05) 59 (0.02) 147 (0.03)
Foetal exposure during pregnancy 16 (0.09) 4 (0.02) 3 (0.01) 15 (3.26) 10 (0.01) 24 (0.01) 80 (0.02)
Foetal growth restriction 12 (0.07) 3 (0.01) 2 (0.00) 10 (2.17) 3 (0.00) 25 (0.01) 58 (0.01)
Foetal hypokinesia 8 (0.04) 3 (0.01) 0 3 (0.65) 9 (0.01) 26 (0.01) 52 (0.01)
Food allergy 0 23 (0.09) 16 (0.03) 1 (0.22) 9 (0.01) 62 (0.02) 113 (0.02)
Food aversion 0 2 (0.01) 11 (0.02) 0 7 (0.01) 52 (0.02) 72 (0.01)
Food refusal 11 (0.06) 2 (0.01) 6 (0.01) 0 4 (0.00) 38 (0.01) 62 (0.01)
Foreign body sensation in eyes 1 (0.01) 0 3 (0.01) 0 2 (0.00) 45 (0.01) 51 (0.01)
Formication 0 6 (0.02) 38 (0.08) 1 (0.22) 20 (0.02) 180 (0.05) 248 (0.05)
Fracture 2 (0.01) 2 (0.01) 3 (0.01) 0 29 (0.03) 26 (0.01) 66 (0.01)
Freezing phenomenon 0 2 (0.01) 11 (0.02) 0 5 (0.01) 119 (0.04) 137 (0.03)
Frequent bowel movements 1 (0.01) 2 (0.01) 9 (0.02) 0 13 (0.02) 62 (0.02) 88 (0.02)
Full blood count 3 (0.02) 51 (0.20) 13 (0.03) 0 46 (0.05) 53 (0.02) 167 (0.03)
Full blood count abnormal 2 (0.01) 16 (0.06) 6 (0.01) 1 (0.22) 23 (0.03) 20 (0.01) 70 (0.01)
Furuncle 1 (0.01) 3 (0.01) 5 (0.01) 0 7 (0.01) 56 (0.02) 72 (0.01)
Gait disturbance 41 (0.22) 203 (0.80) 812 (1.66) 1 (0.22) 936 (1.09) 1116 (0.33) 3249 (0.63)
Gait inability 33 (0.18) 95 (0.37) 370 (0.76) 1 (0.22) 344 (0.40) 337 (0.10) 1246 (0.24)
Gamma-glutamyltransferase increased 0 2 (0.01) 4 (0.01) 0 18 (0.02) 27 (0.01) 56 (0.01)
Gastric disorder 2 (0.01) 3 (0.01) 7 (0.01) 0 10 (0.01) 33 (0.01) 56 (0.01)
Gastric haemorrhage 12 (0.07) 6 (0.02) 3 (0.01) 0 17 (0.02) 16 (0.00) 59 (0.01)
Gastric ulcer 1 (0.01) 3 (0.01) 1 (0.00) 0 21 (0.02) 42 (0.01) 73 (0.01)
Gastritis 3 (0.02) 6 (0.02) 48 (0.10) 0 60 (0.07) 126 (0.04) 248 (0.05)
Gastroenteritis 3 (0.02) 8 (0.03) 8 (0.02) 0 76 (0.09) 58 (0.02) 159 (0.03)
Gastroenteritis viral 2 (0.01) 1 (0.00) 8 (0.02) 0 8 (0.01) 75 (0.02) 95 (0.02)
Gastrointestinal disorder 8 (0.04) 13 (0.05) 63 (0.13) 0 81 (0.09) 154 (0.05) 326 (0.06)
Gastrointestinal haemorrhage 65 (0.36) 50 (0.20) 9 (0.02) 0 87 (0.10) 56 (0.02) 285 (0.06)
Gastrointestinal inflammation 3 (0.02) 5 (0.02) 5 (0.01) 0 22 (0.03) 16 (0.00) 53 (0.01)
Gastrointestinal pain 0 9 (0.04) 95 (0.19) 0 81 (0.09) 351 (0.10) 543 (0.11)
Gastrointestinal sounds abnormal 0 1 (0.00) 10 (0.02) 0 7 (0.01) 35 (0.01) 53 (0.01)
Gastrooesophageal reflux disease 4 (0.02) 21 (0.08) 84 (0.17) 0 63 (0.07) 256 (0.08) 432 (0.08)
Gaze palsy 6 (0.03) 16 (0.06) 7 (0.01) 0 31 (0.04) 97 (0.03) 167 (0.03)
General physical health deterioration 334 (1.83) 78 (0.31) 74 (0.15) 0 350 (0.41) 110 (0.03) 1035 (0.20)
Generalised oedema 9 (0.05) 12 (0.05) 6 (0.01) 0 36 (0.04) 41 (0.01) 110 (0.02)
Generalised tonic-clonic seizure 16 (0.09) 81 (0.32) 24 (0.05) 0 247 (0.29) 332 (0.10) 716 (0.14)
Genital haemorrhage 0 2 (0.01) 3 (0.01) 0 9 (0.01) 89 (0.03) 104 (0.02)
Genital herpes 0 0 27 (0.06) 0 13 (0.02) 122 (0.04) 162 (0.03)
Giant cell arteritis 4 (0.02) 19 (0.07) 28 (0.06) 0 90 (0.10) 84 (0.02) 229 (0.04)
Gingival bleeding 0 36 (0.14) 27 (0.06) 0 59 (0.07) 161 (0.05) 288 (0.06)
Gingival pain 0 3 (0.01) 37 (0.08) 1 (0.22) 9 (0.01) 215 (0.06) 268 (0.05)
Gingival swelling 0 3 (0.01) 12 (0.02) 0 8 (0.01) 61 (0.02) 85 (0.02)
Glaucoma 1 (0.01) 0 14 (0.03) 0 15 (0.02) 49 (0.01) 83 (0.02)
Glomerulonephritis minimal lesion 0 3 (0.01) 2 (0.00) 0 26 (0.03) 23 (0.01) 54 (0.01)
Glossitis 0 4 (0.02) 4 (0.01) 0 6 (0.01) 47 (0.01) 62 (0.01)
Glossodynia 0 5 (0.02) 43 (0.09) 0 15 (0.02) 251 (0.07) 315 (0.06)
Goitre 0 2 (0.01) 13 (0.03) 0 18 (0.02) 39 (0.01) 73 (0.01)
Gout 1 (0.01) 4 (0.02) 60 (0.12) 0 46 (0.05) 191 (0.06) 304 (0.06)
Grip strength decreased 2 (0.01) 4 (0.02) 67 (0.14) 0 30 (0.03) 86 (0.03) 190 (0.04)
Groin pain 6 (0.03) 16 (0.06) 86 (0.18) 0 53 (0.06) 253 (0.08) 426 (0.08)
Guillain-Barre syndrome 38 (0.21) 375 (1.48) 358 (0.73) 1 (0.22) 1352 (1.57) 534 (0.16) 2725 (0.53)
Haematemesis 63 (0.35) 40 (0.16) 18 (0.04) 0 92 (0.11) 180 (0.05) 419 (0.08)
Haematochezia 9 (0.05) 18 (0.07) 31 (0.06) 1 (0.22) 128 (0.15) 536 (0.16) 739 (0.14)
Haematocrit decreased 5 (0.03) 2 (0.01) 0 0 31 (0.04) 17 (0.01) 58 (0.01)
Haematoma 23 (0.13) 85 (0.34) 86 (0.18) 2 (0.43) 228 (0.27) 395 (0.12) 842 (0.16)
Haematuria 10 (0.05) 30 (0.12) 20 (0.04) 0 116 (0.14) 200 (0.06) 396 (0.08)
Haemoglobin decreased 21 (0.12) 39 (0.15) 12 (0.02) 1 (0.22) 113 (0.13) 56 (0.02) 262 (0.05)
Haemolysis 5 (0.03) 14 (0.06) 1 (0.00) 0 24 (0.03) 27 (0.01) 73 (0.01)
Haemolytic anaemia 5 (0.03) 21 (0.08) 3 (0.01) 0 44 (0.05) 27 (0.01) 106 (0.02)
Haemophagocytic lymphohistiocytosis 16 (0.09) 36 (0.14) 0 0 34 (0.04) 8 (0.00) 103 (0.02)
Haemoptysis 39 (0.21) 94 (0.37) 25 (0.05) 0 137 (0.16) 156 (0.05) 476 (0.09)
Haemorrhage 73 (0.40) 177 (0.70) 147 (0.30) 13 (2.83) 277 (0.32) 2299 (0.68) 3045 (0.59)
Haemorrhage in pregnancy 0 4 (0.02) 0 2 (0.43) 10 (0.01) 38 (0.01) 54 (0.01)
Haemorrhage intracranial 67 (0.37) 50 (0.20) 10 (0.02) 0 36 (0.04) 17 (0.01) 195 (0.04)
Haemorrhage subcutaneous 3 (0.02) 1 (0.00) 4 (0.01) 0 19 (0.02) 185 (0.06) 224 (0.04)
Haemorrhage urinary tract 2 (0.01) 12 (0.05) 7 (0.01) 0 19 (0.02) 122 (0.04) 165 (0.03)
Haemorrhagic diathesis 2 (0.01) 7 (0.03) 1 (0.00) 0 11 (0.01) 33 (0.01) 60 (0.01)
Haemorrhagic stroke 117 (0.64) 72 (0.28) 16 (0.03) 0 69 (0.08) 28 (0.01) 311 (0.06)
Haemorrhagic transformation stroke 17 (0.09) 13 (0.05) 2 (0.00) 0 16 (0.02) 0 51 (0.01)
Haemorrhoids 2 (0.01) 2 (0.01) 16 (0.03) 0 15 (0.02) 88 (0.03) 124 (0.02)
Haemorrhoids thrombosed 0 2 (0.01) 6 (0.01) 0 14 (0.02) 59 (0.02) 81 (0.02)
Hallucination 12 (0.07) 49 (0.19) 204 (0.42) 0 143 (0.17) 1366 (0.41) 1810 (0.35)
Hallucination, auditory 0 7 (0.03) 10 (0.02) 0 20 (0.02) 111 (0.03) 153 (0.03)
Hallucination, visual 2 (0.01) 8 (0.03) 15 (0.03) 0 25 (0.03) 169 (0.05) 223 (0.04)
Hangover 0 0 41 (0.08) 0 6 (0.01) 181 (0.05) 229 (0.04)
Head banging 0 2 (0.01) 34 (0.07) 0 8 (0.01) 34 (0.01) 79 (0.02)
Head discomfort 3 (0.02) 59 (0.23) 312 (0.64) 0 246 (0.29) 914 (0.27) 1560 (0.30)
Head injury 18 (0.10) 54 (0.21) 27 (0.06) 0 143 (0.17) 165 (0.05) 433 (0.08)
Headache 482 (2.64) 2197 (8.67) 16082 (32.90) 31 (6.74) 9308 (10.84) 76999 (22.91) 105704 (20.53)
Heart rate 0 24 (0.09) 84 (0.17) 0 83 (0.10) 803 (0.24) 994 (0.19)
Heart rate abnormal 3 (0.02) 19 (0.07) 30 (0.06) 0 58 (0.07) 150 (0.04) 264 (0.05)
Heart rate decreased 12 (0.07) 62 (0.24) 40 (0.08) 1 (0.22) 137 (0.16) 336 (0.10) 610 (0.12)
Heart rate increased 35 (0.19) 320 (1.26) 565 (1.16) 5 (1.09) 921 (1.07) 2945 (0.88) 4889 (0.95)
Heart rate irregular 6 (0.03) 52 (0.21) 109 (0.22) 3 (0.65) 153 (0.18) 404 (0.12) 738 (0.14)
Heavy menstrual bleeding 0 68 (0.27) 625 (1.28) 3 (0.65) 284 (0.33) 6426 (1.91) 7424 (1.44)
Hemianaesthesia 1 (0.01) 7 (0.03) 22 (0.05) 0 57 (0.07) 73 (0.02) 162 (0.03)
Hemianopia 1 (0.01) 10 (0.04) 9 (0.02) 0 26 (0.03) 14 (0.00) 69 (0.01)
Hemiparaesthesia 2 (0.01) 5 (0.02) 16 (0.03) 0 56 (0.07) 161 (0.05) 245 (0.05)
Hemiparesis 82 (0.45) 201 (0.79) 188 (0.38) 0 543 (0.63) 428 (0.13) 1545 (0.30)
Hemiplegia 35 (0.19) 98 (0.39) 106 (0.22) 0 208 (0.24) 174 (0.05) 707 (0.14)
Hemiplegic migraine 0 5 (0.02) 29 (0.06) 0 19 (0.02) 41 (0.01) 95 (0.02)
Henoch-Schonlein purpura 1 (0.01) 2 (0.01) 9 (0.02) 0 52 (0.06) 34 (0.01) 99 (0.02)
Heparin-induced thrombocytopenia 5 (0.03) 24 (0.09) 2 (0.00) 0 11 (0.01) 7 (0.00) 52 (0.01)
Heparin-induced thrombocytopenia test positive 9 (0.05) 13 (0.05) 0 0 38 (0.04) 3 (0.00) 69 (0.01)
Hepatic cirrhosis 10 (0.05) 7 (0.03) 3 (0.01) 0 21 (0.02) 10 (0.00) 59 (0.01)
Hepatic cytolysis 2 (0.01) 4 (0.02) 0 0 58 (0.07) 49 (0.01) 114 (0.02)
Hepatic enzyme increased 4 (0.02) 14 (0.06) 6 (0.01) 0 63 (0.07) 47 (0.01) 141 (0.03)
Hepatic failure 39 (0.21) 23 (0.09) 2 (0.00) 0 24 (0.03) 9 (0.00) 114 (0.02)
Hepatic function abnormal 7 (0.04) 13 (0.05) 6 (0.01) 0 91 (0.11) 46 (0.01) 173 (0.03)
Hepatic pain 1 (0.01) 6 (0.02) 30 (0.06) 0 12 (0.01) 76 (0.02) 126 (0.02)
Hepatic steatosis 6 (0.03) 5 (0.02) 6 (0.01) 0 28 (0.03) 12 (0.00) 60 (0.01)
Hepatic vein thrombosis 8 (0.04) 12 (0.05) 2 (0.00) 0 27 (0.03) 9 (0.00) 63 (0.01)
Hepatitis 6 (0.03) 11 (0.04) 6 (0.01) 0 77 (0.09) 96 (0.03) 202 (0.04)
Hepatitis acute 6 (0.03) 7 (0.03) 1 (0.00) 0 55 (0.06) 29 (0.01) 98 (0.02)
Herpes ophthalmic 0 1 (0.00) 5 (0.01) 0 11 (0.01) 92 (0.03) 110 (0.02)
Herpes simplex 0 4 (0.02) 13 (0.03) 0 17 (0.02) 78 (0.02) 112 (0.02)
Herpes virus infection 0 2 (0.01) 13 (0.03) 0 17 (0.02) 61 (0.02) 93 (0.02)
Herpes zoster 19 (0.10) 58 (0.23) 452 (0.92) 0 700 (0.82) 3718 (1.11) 4970 (0.97)
Herpes zoster oticus 1 (0.01) 3 (0.01) 24 (0.05) 0 42 (0.05) 80 (0.02) 152 (0.03)
Hiatus hernia 4 (0.02) 8 (0.03) 3 (0.01) 0 33 (0.04) 11 (0.00) 59 (0.01)
Hiccups 2 (0.01) 6 (0.02) 8 (0.02) 0 12 (0.01) 51 (0.02) 79 (0.02)
Hip fracture 8 (0.04) 2 (0.01) 6 (0.01) 0 28 (0.03) 18 (0.01) 68 (0.01)
Hordeolum 0 2 (0.01) 7 (0.01) 0 4 (0.00) 44 (0.01) 58 (0.01)
Hormone level abnormal 0 2 (0.01) 23 (0.05) 0 7 (0.01) 103 (0.03) 136 (0.03)
Hospitalisation 14 (0.08) 9 (0.04) 3 (0.01) 0 346 (0.40) 1 (0.00) 411 (0.08)
Hot flush 4 (0.02) 37 (0.15) 337 (0.69) 1 (0.22) 199 (0.23) 2253 (0.67) 2848 (0.55)
Hunger 1 (0.01) 2 (0.01) 7 (0.01) 0 4 (0.00) 81 (0.02) 96 (0.02)
Hydrocephalus 15 (0.08) 20 (0.08) 2 (0.00) 0 17 (0.02) 9 (0.00) 69 (0.01)
Hyperacusis 0 12 (0.05) 134 (0.27) 0 49 (0.06) 162 (0.05) 359 (0.07)
Hyperaesthesia 1 (0.01) 7 (0.03) 96 (0.20) 1 (0.22) 45 (0.05) 332 (0.10) 486 (0.09)
Hyperaesthesia teeth 0 3 (0.01) 6 (0.01) 0 3 (0.00) 55 (0.02) 67 (0.01)
Hypercoagulation 5 (0.03) 16 (0.06) 3 (0.01) 0 21 (0.02) 20 (0.01) 67 (0.01)
Hyperglycaemia 14 (0.08) 37 (0.15) 25 (0.05) 0 92 (0.11) 204 (0.06) 386 (0.07)
Hyperhidrosis 70 (0.38) 336 (1.33) 1520 (3.11) 3 (0.65) 1005 (1.17) 9033 (2.69) 12058 (2.34)
Hyperkalaemia 26 (0.14) 9 (0.04) 1 (0.00) 0 39 (0.05) 13 (0.00) 101 (0.02)
Hyperpyrexia 39 (0.21) 34 (0.13) 25 (0.05) 0 128 (0.15) 1485 (0.44) 1720 (0.33)
Hypersensitivity 20 (0.11) 421 (1.66) 341 (0.70) 2 (0.43) 1013 (1.18) 2735 (0.81) 4600 (0.89)
Hypersomnia 8 (0.04) 37 (0.15) 117 (0.24) 1 (0.22) 66 (0.08) 402 (0.12) 647 (0.13)
Hypertension 121 (0.66) 552 (2.18) 428 (0.88) 5 (1.09) 1824 (2.12) 3621 (1.08) 6718 (1.30)
Hypertensive crisis 13 (0.07) 73 (0.29) 12 (0.02) 0 292 (0.34) 580 (0.17) 987 (0.19)
Hypertensive emergency 2 (0.01) 12 (0.05) 0 0 29 (0.03) 23 (0.01) 68 (0.01)
Hypertensive urgency 0 6 (0.02) 2 (0.00) 0 14 (0.02) 36 (0.01) 59 (0.01)
Hyperthermia 11 (0.06) 10 (0.04) 21 (0.04) 0 46 (0.05) 104 (0.03) 195 (0.04)
Hyperthyroidism 1 (0.01) 16 (0.06) 33 (0.07) 1 (0.22) 44 (0.05) 221 (0.07) 320 (0.06)
Hyperventilation 7 (0.04) 27 (0.11) 26 (0.05) 0 198 (0.23) 256 (0.08) 529 (0.10)
Hypervolaemia 5 (0.03) 9 (0.04) 1 (0.00) 0 40 (0.05) 8 (0.00) 71 (0.01)
Hypoacusis 2 (0.01) 18 (0.07) 265 (0.54) 0 100 (0.12) 466 (0.14) 860 (0.17)
Hypoaesthesia 38 (0.21) 570 (2.25) 2089 (4.27) 2 (0.43) 2375 (2.77) 6493 (1.93) 11739 (2.28)
Hypoaesthesia eye 0 2 (0.01) 10 (0.02) 0 9 (0.01) 35 (0.01) 57 (0.01)
Hypoaesthesia oral 4 (0.02) 86 (0.34) 142 (0.29) 1 (0.22) 264 (0.31) 854 (0.25) 1378 (0.27)
Hypogeusia 1 (0.01) 1 (0.00) 28 (0.06) 0 9 (0.01) 17 (0.01) 58 (0.01)
Hypoglycaemia 18 (0.10) 40 (0.16) 20 (0.04) 1 (0.22) 70 (0.08) 198 (0.06) 353 (0.07)
Hypokalaemia 16 (0.09) 27 (0.11) 7 (0.01) 0 91 (0.11) 49 (0.01) 219 (0.04)
Hypokinesia 8 (0.04) 19 (0.07) 102 (0.21) 1 (0.22) 101 (0.12) 246 (0.07) 506 (0.10)
Hypomenorrhoea 0 1 (0.00) 48 (0.10) 1 (0.22) 7 (0.01) 379 (0.11) 436 (0.08)
Hyponatraemia 15 (0.08) 42 (0.17) 12 (0.02) 0 129 (0.15) 9 (0.00) 227 (0.04)
Hypophagia 41 (0.22) 15 (0.06) 13 (0.03) 0 110 (0.13) 53 (0.02) 252 (0.05)
Hypopnoea 14 (0.08) 41 (0.16) 49 (0.10) 0 35 (0.04) 249 (0.07) 404 (0.08)
Hyporeflexia 1 (0.01) 12 (0.05) 13 (0.03) 0 32 (0.04) 18 (0.01) 80 (0.02)
Hyporesponsive to stimuli 15 (0.08) 6 (0.02) 2 (0.00) 0 23 (0.03) 12 (0.00) 62 (0.01)
Hypotension 214 (1.17) 346 (1.37) 223 (0.46) 0 822 (0.96) 1388 (0.41) 3135 (0.61)
Hypothermia 18 (0.10) 23 (0.09) 19 (0.04) 0 31 (0.04) 226 (0.07) 333 (0.06)
Hypothyroidism 1 (0.01) 4 (0.02) 29 (0.06) 0 30 (0.03) 155 (0.05) 234 (0.05)
Hypotonia 10 (0.05) 22 (0.09) 37 (0.08) 0 174 (0.20) 98 (0.03) 348 (0.07)
Hypotonic-hyporesponsive episode 7 (0.04) 2 (0.01) 0 0 11 (0.01) 50 (0.01) 71 (0.01)
Hypovolaemic shock 15 (0.08) 9 (0.04) 0 0 13 (0.02) 122 (0.04) 166 (0.03)
Hypoxia 175 (0.96) 147 (0.58) 14 (0.03) 0 487 (0.57) 161 (0.05) 1086 (0.21)
IIIrd nerve paralysis 0 2 (0.01) 11 (0.02) 0 34 (0.04) 39 (0.01) 90 (0.02)
IgA nephropathy 0 1 (0.00) 8 (0.02) 0 16 (0.02) 34 (0.01) 60 (0.01)
Ileus 7 (0.04) 5 (0.02) 2 (0.00) 0 28 (0.03) 5 (0.00) 55 (0.01)
Illness 56 (0.31) 121 (0.48) 694 (1.42) 4 (0.87) 417 (0.49) 4758 (1.42) 6096 (1.18)
Immediate post-injection reaction 5 (0.03) 37 (0.15) 54 (0.11) 0 40 (0.05) 15 (0.00) 151 (0.03)
Immobile 7 (0.04) 11 (0.04) 48 (0.10) 0 22 (0.03) 100 (0.03) 198 (0.04)
Immune system disorder 4 (0.02) 6 (0.02) 38 (0.08) 0 34 (0.04) 97 (0.03) 191 (0.04)
Immune thrombocytopenia 56 (0.31) 334 (1.32) 16 (0.03) 0 670 (0.78) 366 (0.11) 1490 (0.29)
Immunisation 33 (0.18) 52 (0.21) 183 (0.37) 0 135 (0.16) 2215 (0.66) 2631 (0.51)
Immunisation reaction 0 1 (0.00) 6 (0.01) 0 32 (0.04) 117 (0.03) 165 (0.03)
Immunodeficiency 0 1 (0.00) 7 (0.01) 0 16 (0.02) 61 (0.02) 96 (0.02)
Immunoglobulin therapy 2 (0.01) 28 (0.11) 19 (0.04) 0 50 (0.06) 1 (0.00) 101 (0.02)
Impaired driving ability 3 (0.02) 27 (0.11) 101 (0.21) 0 39 (0.05) 62 (0.02) 242 (0.05)
Impaired quality of life 0 4 (0.02) 43 (0.09) 0 11 (0.01) 45 (0.01) 110 (0.02)
Impaired work ability 5 (0.03) 84 (0.33) 479 (0.98) 2 (0.43) 169 (0.20) 440 (0.13) 1231 (0.24)
Inappropriate schedule of product administration 10 (0.05) 8 (0.03) 48 (0.10) 3 (0.65) 56 (0.07) 322 (0.10) 464 (0.09)
Incoherent 6 (0.03) 7 (0.03) 8 (0.02) 0 38 (0.04) 33 (0.01) 98 (0.02)
Incontinence 10 (0.05) 20 (0.08) 45 (0.09) 0 54 (0.06) 73 (0.02) 216 (0.04)
Incorrect route of product administration 6 (0.03) 7 (0.03) 14 (0.03) 0 31 (0.04) 69 (0.02) 136 (0.03)
Increased appetite 0 1 (0.00) 12 (0.02) 0 3 (0.00) 49 (0.01) 66 (0.01)
Increased tendency to bruise 1 (0.01) 12 (0.05) 34 (0.07) 0 20 (0.02) 104 (0.03) 173 (0.03)
Induration 1 (0.01) 6 (0.02) 13 (0.03) 0 36 (0.04) 65 (0.02) 123 (0.02)
Infarction 36 (0.20) 48 (0.19) 7 (0.01) 0 63 (0.07) 21 (0.01) 183 (0.04)
Infection 42 (0.23) 51 (0.20) 98 (0.20) 1 (0.22) 247 (0.29) 506 (0.15) 971 (0.19)
Infectious mononucleosis 0 4 (0.02) 31 (0.06) 0 18 (0.02) 61 (0.02) 114 (0.02)
Inflammation 17 (0.09) 98 (0.39) 347 (0.71) 1 (0.22) 377 (0.44) 935 (0.28) 1827 (0.35)
Inflammatory marker increased 5 (0.03) 9 (0.04) 14 (0.03) 0 68 (0.08) 27 (0.01) 136 (0.03)
Inflammatory pain 0 2 (0.01) 16 (0.03) 1 (0.22) 4 (0.00) 33 (0.01) 56 (0.01)
Influenza 6 (0.03) 55 (0.22) 702 (1.44) 0 560 (0.65) 5833 (1.74) 7166 (1.39)
Influenza like illness 58 (0.32) 126 (0.50) 1622 (3.32) 1 (0.22) 1039 (1.21) 10936 (3.25) 13848 (2.69)
Initial insomnia 0 3 (0.01) 11 (0.02) 0 8 (0.01) 84 (0.02) 107 (0.02)
Injected limb mobility decreased 2 (0.01) 10 (0.04) 182 (0.37) 0 11 (0.01) 210 (0.06) 416 (0.08)
Injection related reaction 0 1 (0.00) 42 (0.09) 0 7 (0.01) 480 (0.14) 531 (0.10)
Injection site bruising 1 (0.01) 2 (0.01) 20 (0.04) 0 6 (0.01) 95 (0.03) 125 (0.02)
Injection site erythema 6 (0.03) 22 (0.09) 149 (0.30) 0 141 (0.16) 600 (0.18) 921 (0.18)
Injection site hypoaesthesia 0 1 (0.00) 14 (0.03) 0 16 (0.02) 25 (0.01) 56 (0.01)
Injection site induration 1 (0.01) 4 (0.02) 40 (0.08) 0 20 (0.02) 33 (0.01) 98 (0.02)
Injection site inflammation 5 (0.03) 4 (0.02) 16 (0.03) 0 4 (0.00) 38 (0.01) 67 (0.01)
Injection site mass 1 (0.01) 3 (0.01) 64 (0.13) 0 13 (0.02) 838 (0.25) 919 (0.18)
Injection site movement impairment 0 0 30 (0.06) 0 9 (0.01) 18 (0.01) 57 (0.01)
Injection site oedema 0 1 (0.00) 5 (0.01) 0 4 (0.00) 80 (0.02) 90 (0.02)
Injection site pain 26 (0.14) 77 (0.30) 932 (1.91) 1 (0.22) 617 (0.72) 4139 (1.23) 5812 (1.13)
Injection site paraesthesia 0 7 (0.03) 11 (0.02) 0 9 (0.01) 33 (0.01) 60 (0.01)
Injection site pruritus 3 (0.02) 9 (0.04) 49 (0.10) 0 24 (0.03) 244 (0.07) 330 (0.06)
Injection site rash 0 6 (0.02) 32 (0.07) 1 (0.22) 21 (0.02) 228 (0.07) 288 (0.06)
Injection site reaction 5 (0.03) 26 (0.10) 2903 (5.94) 0 108 (0.13) 282 (0.08) 3331 (0.65)
Injection site swelling 6 (0.03) 24 (0.09) 147 (0.30) 0 160 (0.19) 343 (0.10) 686 (0.13)
Injection site warmth 4 (0.02) 10 (0.04) 71 (0.15) 0 18 (0.02) 272 (0.08) 375 (0.07)
Injury 6 (0.03) 15 (0.06) 20 (0.04) 0 45 (0.05) 49 (0.01) 138 (0.03)
Insomnia 25 (0.14) 141 (0.56) 1062 (2.17) 2 (0.43) 377 (0.44) 3962 (1.18) 5610 (1.09)
Intensive care 33 (0.18) 82 (0.32) 7 (0.01) 0 69 (0.08) 0 196 (0.04)
Interchange of vaccine products 19 (0.10) 28 (0.11) 79 (0.16) 1 (0.22) 79 (0.09) 1200 (0.36) 1411 (0.27)
Intermenstrual bleeding 0 12 (0.05) 113 (0.23) 2 (0.43) 64 (0.07) 1092 (0.32) 1289 (0.25)
Internal haemorrhage 19 (0.10) 17 (0.07) 9 (0.02) 0 27 (0.03) 166 (0.05) 250 (0.05)
International normalised ratio decreased 1 (0.01) 10 (0.04) 3 (0.01) 0 14 (0.02) 36 (0.01) 68 (0.01)
International normalised ratio increased 8 (0.04) 26 (0.10) 10 (0.02) 0 47 (0.05) 99 (0.03) 203 (0.04)
Interstitial lung disease 54 (0.30) 38 (0.15) 17 (0.03) 0 116 (0.14) 58 (0.02) 300 (0.06)
Intervertebral disc protrusion 1 (0.01) 3 (0.01) 18 (0.04) 0 26 (0.03) 24 (0.01) 74 (0.01)
Intestinal haemorrhage 3 (0.02) 6 (0.02) 1 (0.00) 0 27 (0.03) 31 (0.01) 69 (0.01)
Intestinal ischaemia 65 (0.36) 38 (0.15) 4 (0.01) 0 43 (0.05) 17 (0.01) 174 (0.03)
Intestinal obstruction 20 (0.11) 10 (0.04) 3 (0.01) 0 40 (0.05) 28 (0.01) 102 (0.02)
Intracardiac thrombus 31 (0.17) 52 (0.21) 8 (0.02) 0 52 (0.06) 12 (0.00) 165 (0.03)
Intracranial aneurysm 24 (0.13) 25 (0.10) 3 (0.01) 0 25 (0.03) 10 (0.00) 95 (0.02)
Intracranial pressure increased 23 (0.13) 16 (0.06) 11 (0.02) 0 34 (0.04) 48 (0.01) 148 (0.03)
Intraventricular haemorrhage 15 (0.08) 20 (0.08) 2 (0.00) 0 17 (0.02) 2 (0.00) 59 (0.01)
Iridocyclitis 1 (0.01) 0 12 (0.02) 0 11 (0.01) 92 (0.03) 119 (0.02)
Iron deficiency anaemia 2 (0.01) 10 (0.04) 7 (0.01) 0 20 (0.02) 21 (0.01) 63 (0.01)
Irregular breathing 3 (0.02) 4 (0.02) 6 (0.01) 0 3 (0.00) 38 (0.01) 54 (0.01)
Irritability 9 (0.05) 13 (0.05) 56 (0.11) 0 62 (0.07) 414 (0.12) 559 (0.11)
Irritable bowel syndrome 0 5 (0.02) 41 (0.08) 0 21 (0.02) 166 (0.05) 235 (0.05)
Ischaemia 17 (0.09) 39 (0.15) 23 (0.05) 0 70 (0.08) 23 (0.01) 176 (0.03)
Ischaemic cerebral infarction 15 (0.08) 61 (0.24) 13 (0.03) 0 78 (0.09) 14 (0.00) 184 (0.04)
Ischaemic stroke 136 (0.75) 382 (1.51) 177 (0.36) 0 995 (1.16) 147 (0.04) 1854 (0.36)
Jaundice 18 (0.10) 17 (0.07) 6 (0.01) 0 109 (0.13) 67 (0.02) 227 (0.04)
Joint dislocation 0 3 (0.01) 15 (0.03) 0 11 (0.01) 24 (0.01) 58 (0.01)
Joint effusion 2 (0.01) 1 (0.00) 18 (0.04) 0 19 (0.02) 36 (0.01) 77 (0.01)
Joint injury 1 (0.01) 5 (0.02) 22 (0.05) 0 16 (0.02) 23 (0.01) 70 (0.01)
Joint lock 1 (0.01) 1 (0.00) 26 (0.05) 0 10 (0.01) 68 (0.02) 106 (0.02)
Joint noise 0 1 (0.00) 27 (0.06) 0 0 62 (0.02) 90 (0.02)
Joint range of motion decreased 2 (0.01) 10 (0.04) 141 (0.29) 0 31 (0.04) 292 (0.09) 484 (0.09)
Joint stiffness 1 (0.01) 12 (0.05) 189 (0.39) 0 51 (0.06) 528 (0.16) 787 (0.15)
Joint swelling 8 (0.04) 65 (0.26) 428 (0.88) 0 227 (0.26) 1153 (0.34) 1904 (0.37)
Joint warmth 0 0 15 (0.03) 0 4 (0.00) 43 (0.01) 62 (0.01)
Jugular vein thrombosis 9 (0.05) 50 (0.20) 2 (0.00) 0 67 (0.08) 37 (0.01) 169 (0.03)
Kidney infection 2 (0.01) 14 (0.06) 19 (0.04) 0 46 (0.05) 130 (0.04) 217 (0.04)
Laboratory test 11 (0.06) 58 (0.23) 22 (0.05) 0 44 (0.05) 42 (0.01) 177 (0.03)
Laboratory test abnormal 0 7 (0.03) 7 (0.01) 0 26 (0.03) 11 (0.00) 51 (0.01)
Labyrinthitis 1 (0.01) 3 (0.01) 63 (0.13) 0 35 (0.04) 189 (0.06) 292 (0.06)
Lacrimation increased 1 (0.01) 15 (0.06) 73 (0.15) 0 60 (0.07) 335 (0.10) 490 (0.10)
Lactic acidosis 19 (0.10) 11 (0.04) 3 (0.01) 0 36 (0.04) 6 (0.00) 85 (0.02)
Lacunar infarction 4 (0.02) 24 (0.09) 3 (0.01) 0 64 (0.07) 31 (0.01) 133 (0.03)
Lacunar stroke 0 16 (0.06) 10 (0.02) 0 26 (0.03) 16 (0.00) 68 (0.01)
Language disorder 1 (0.01) 11 (0.04) 14 (0.03) 0 102 (0.12) 22 (0.01) 158 (0.03)
Laryngeal oedema 6 (0.03) 77 (0.30) 0 0 76 (0.09) 240 (0.07) 411 (0.08)
Laryngitis 1 (0.01) 2 (0.01) 12 (0.02) 0 10 (0.01) 58 (0.02) 83 (0.02)
Laryngospasm 1 (0.01) 19 (0.07) 3 (0.01) 0 18 (0.02) 43 (0.01) 84 (0.02)
Left ventricular dysfunction 7 (0.04) 28 (0.11) 5 (0.01) 0 44 (0.05) 7 (0.00) 97 (0.02)
Left ventricular failure 15 (0.08) 17 (0.07) 1 (0.00) 0 31 (0.04) 5 (0.00) 73 (0.01)
Lethargy 87 (0.48) 148 (0.58) 647 (1.32) 1 (0.22) 410 (0.48) 4562 (1.36) 5912 (1.15)
Leukocytosis 14 (0.08) 24 (0.09) 2 (0.00) 0 97 (0.11) 13 (0.00) 164 (0.03)
Leukopenia 10 (0.05) 17 (0.07) 7 (0.01) 0 70 (0.08) 92 (0.03) 203 (0.04)
Lichen planus 0 0 12 (0.02) 0 3 (0.00) 36 (0.01) 51 (0.01)
Limb discomfort 11 (0.06) 87 (0.34) 509 (1.04) 0 941 (1.10) 2479 (0.74) 4065 (0.79)
Limb injury 5 (0.03) 9 (0.04) 126 (0.26) 1 (0.22) 30 (0.03) 272 (0.08) 447 (0.09)
Limb mass 0 5 (0.02) 9 (0.02) 0 9 (0.01) 60 (0.02) 86 (0.02)
Lip dry 0 6 (0.02) 7 (0.01) 0 4 (0.00) 74 (0.02) 92 (0.02)
Lip oedema 1 (0.01) 14 (0.06) 12 (0.02) 0 62 (0.07) 205 (0.06) 299 (0.06)
Lip pain 0 1 (0.00) 12 (0.02) 0 8 (0.01) 79 (0.02) 103 (0.02)
Lip pruritus 0 11 (0.04) 4 (0.01) 0 13 (0.02) 61 (0.02) 90 (0.02)
Lip swelling 4 (0.02) 173 (0.68) 96 (0.20) 1 (0.22) 289 (0.34) 1185 (0.35) 1769 (0.34)
Listless 3 (0.02) 3 (0.01) 24 (0.05) 0 7 (0.01) 103 (0.03) 141 (0.03)
Livedo reticularis 9 (0.05) 12 (0.05) 15 (0.03) 0 17 (0.02) 73 (0.02) 132 (0.03)
Liver disorder 8 (0.04) 22 (0.09) 19 (0.04) 0 67 (0.08) 40 (0.01) 164 (0.03)
Liver function test abnormal 6 (0.03) 13 (0.05) 12 (0.02) 0 48 (0.06) 50 (0.01) 142 (0.03)
Liver function test increased 2 (0.01) 10 (0.04) 7 (0.01) 0 22 (0.03) 35 (0.01) 79 (0.02)
Liver injury 2 (0.01) 13 (0.05) 10 (0.02) 0 30 (0.03) 43 (0.01) 106 (0.02)
Local reaction 8 (0.04) 12 (0.05) 62 (0.13) 0 69 (0.08) 107 (0.03) 258 (0.05)
Localised infection 1 (0.01) 4 (0.02) 16 (0.03) 0 27 (0.03) 113 (0.03) 163 (0.03)
Localised oedema 3 (0.02) 25 (0.10) 27 (0.06) 0 39 (0.05) 104 (0.03) 201 (0.04)
Loss of consciousness 324 (1.78) 633 (2.50) 284 (0.58) 2 (0.43) 1466 (1.71) 6429 (1.91) 9528 (1.85)
Loss of control of legs 0 9 (0.04) 16 (0.03) 0 26 (0.03) 81 (0.02) 140 (0.03)
Loss of libido 0 1 (0.00) 22 (0.05) 0 4 (0.00) 29 (0.01) 57 (0.01)
Loss of personal independence in daily activities 7 (0.04) 83 (0.33) 494 (1.01) 0 154 (0.18) 419 (0.12) 1218 (0.24)
Lower respiratory tract infection 35 (0.19) 35 (0.14) 73 (0.15) 0 73 (0.09) 427 (0.13) 662 (0.13)
Lumbar puncture 1 (0.01) 21 (0.08) 31 (0.06) 0 46 (0.05) 7 (0.00) 107 (0.02)
Lung consolidation 8 (0.04) 8 (0.03) 1 (0.00) 0 32 (0.04) 3 (0.00) 64 (0.01)
Lung disorder 40 (0.22) 28 (0.11) 24 (0.05) 0 137 (0.16) 65 (0.02) 310 (0.06)
Lung infiltration 36 (0.20) 28 (0.11) 0 0 138 (0.16) 6 (0.00) 227 (0.04)
Lung neoplasm malignant 21 (0.12) 8 (0.03) 3 (0.01) 0 9 (0.01) 21 (0.01) 68 (0.01)
Lung opacity 22 (0.12) 55 (0.22) 5 (0.01) 0 186 (0.22) 12 (0.00) 295 (0.06)
Lyme disease 0 1 (0.00) 10 (0.02) 0 18 (0.02) 90 (0.03) 125 (0.02)
Lymph node pain 3 (0.02) 10 (0.04) 173 (0.35) 0 63 (0.07) 1529 (0.45) 1787 (0.35)
Lymphadenitis 1 (0.01) 14 (0.06) 33 (0.07) 0 61 (0.07) 251 (0.07) 363 (0.07)
Lymphadenopathy 25 (0.14) 178 (0.70) 1359 (2.78) 10 (2.17) 793 (0.92) 9306 (2.77) 11737 (2.28)
Lymphangitis 0 1 (0.00) 3 (0.01) 0 14 (0.02) 61 (0.02) 79 (0.02)
Lymphocyte count decreased 0 2 (0.01) 2 (0.00) 0 25 (0.03) 19 (0.01) 51 (0.01)
Lymphoedema 1 (0.01) 8 (0.03) 37 (0.08) 0 14 (0.02) 161 (0.05) 224 (0.04)
Lymphoma 13 (0.07) 13 (0.05) 7 (0.01) 0 14 (0.02) 86 (0.03) 138 (0.03)
Lymphopenia 4 (0.02) 17 (0.07) 5 (0.01) 0 44 (0.05) 30 (0.01) 101 (0.02)
Macular oedema 0 0 27 (0.06) 0 7 (0.01) 40 (0.01) 79 (0.02)
Magnetic resonance imaging 1 (0.01) 43 (0.17) 27 (0.06) 1 (0.22) 50 (0.06) 36 (0.01) 158 (0.03)
Magnetic resonance imaging abnormal 1 (0.01) 20 (0.08) 7 (0.01) 0 22 (0.03) 13 (0.00) 64 (0.01)
Magnetic resonance imaging head 1 (0.01) 18 (0.07) 17 (0.03) 0 32 (0.04) 36 (0.01) 104 (0.02)
Magnetic resonance imaging head abnormal 6 (0.03) 45 (0.18) 38 (0.08) 0 79 (0.09) 6 (0.00) 174 (0.03)
Major depression 0 4 (0.02) 11 (0.02) 0 8 (0.01) 40 (0.01) 64 (0.01)
Malaise 636 (3.49) 912 (3.60) 5669 (11.60) 10 (2.17) 3447 (4.01) 14384 (4.28) 25402 (4.93)
Mania 0 6 (0.02) 8 (0.02) 0 15 (0.02) 27 (0.01) 56 (0.01)
Mass 2 (0.01) 9 (0.04) 26 (0.05) 0 18 (0.02) 121 (0.04) 186 (0.04)
Mast cell activation syndrome 0 4 (0.02) 6 (0.01) 0 2 (0.00) 34 (0.01) 51 (0.01)
Mastication disorder 0 7 (0.03) 20 (0.04) 0 16 (0.02) 18 (0.01) 65 (0.01)
Mastitis 0 0 8 (0.02) 0 13 (0.02) 230 (0.07) 251 (0.05)
Maternal exposure during breast feeding 1 (0.01) 13 (0.05) 78 (0.16) 7 (1.52) 25 (0.03) 1040 (0.31) 1167 (0.23)
Maternal exposure during pregnancy 39 (0.21) 53 (0.21) 54 (0.11) 94 (20.43) 159 (0.19) 614 (0.18) 1035 (0.20)
Mechanical ventilation 22 (0.12) 30 (0.12) 4 (0.01) 0 16 (0.02) 0 74 (0.01)
Medication error 6 (0.03) 7 (0.03) 7 (0.01) 0 14 (0.02) 49 (0.01) 84 (0.02)
Melaena 18 (0.10) 16 (0.06) 2 (0.00) 0 48 (0.06) 60 (0.02) 157 (0.03)
Memory impairment 11 (0.06) 62 (0.24) 294 (0.60) 0 245 (0.29) 478 (0.14) 1129 (0.22)
Meniere's disease 1 (0.01) 2 (0.01) 39 (0.08) 0 22 (0.03) 100 (0.03) 166 (0.03)
Meningitis 5 (0.03) 15 (0.06) 9 (0.02) 0 106 (0.12) 54 (0.02) 201 (0.04)
Meningitis aseptic 0 10 (0.04) 0 0 91 (0.11) 23 (0.01) 125 (0.02)
Meningitis viral 1 (0.01) 7 (0.03) 4 (0.01) 0 48 (0.06) 27 (0.01) 88 (0.02)
Menometrorrhagia 0 4 (0.02) 12 (0.02) 0 11 (0.01) 53 (0.02) 81 (0.02)
Menopausal symptoms 0 1 (0.00) 7 (0.01) 0 1 (0.00) 48 (0.01) 57 (0.01)
Menopause 0 2 (0.01) 15 (0.03) 0 2 (0.00) 67 (0.02) 86 (0.02)
Menstrual discomfort 0 0 3 (0.01) 0 10 (0.01) 40 (0.01) 53 (0.01)
Menstrual disorder 1 (0.01) 27 (0.11) 287 (0.59) 6 (1.30) 106 (0.12) 1847 (0.55) 2287 (0.44)
Menstruation delayed 0 14 (0.06) 267 (0.55) 5 (1.09) 36 (0.04) 2647 (0.79) 2972 (0.58)
Menstruation irregular 0 17 (0.07) 289 (0.59) 6 (1.30) 86 (0.10) 2447 (0.73) 2856 (0.55)
Mental disorder 2 (0.01) 13 (0.05) 30 (0.06) 0 51 (0.06) 60 (0.02) 163 (0.03)
Mental fatigue 1 (0.01) 14 (0.06) 152 (0.31) 0 22 (0.03) 459 (0.14) 650 (0.13)
Mental impairment 10 (0.05) 23 (0.09) 89 (0.18) 0 53 (0.06) 473 (0.14) 677 (0.13)
Mental status changes 42 (0.23) 49 (0.19) 10 (0.02) 0 187 (0.22) 3 (0.00) 306 (0.06)
Mesenteric vein thrombosis 21 (0.12) 61 (0.24) 3 (0.01) 0 107 (0.12) 26 (0.01) 228 (0.04)
Metabolic acidosis 24 (0.13) 23 (0.09) 0 0 23 (0.03) 4 (0.00) 80 (0.02)
Metabolic function test 4 (0.02) 26 (0.10) 6 (0.01) 0 25 (0.03) 26 (0.01) 87 (0.02)
Metamorphopsia 0 4 (0.02) 14 (0.03) 0 9 (0.01) 56 (0.02) 84 (0.02)
Micturition urgency 2 (0.01) 2 (0.01) 24 (0.05) 0 29 (0.03) 105 (0.03) 167 (0.03)
Middle insomnia 0 6 (0.02) 26 (0.05) 0 14 (0.02) 123 (0.04) 170 (0.03)
Migraine 11 (0.06) 180 (0.71) 1849 (3.78) 0 679 (0.79) 7710 (2.29) 10473 (2.03)
Migraine with aura 0 4 (0.02) 108 (0.22) 1 (0.22) 56 (0.07) 430 (0.13) 602 (0.12)
Migraine without aura 0 0 7 (0.01) 0 2 (0.00) 47 (0.01) 56 (0.01)
Miliaria 0 3 (0.01) 22 (0.05) 0 6 (0.01) 152 (0.05) 184 (0.04)
Miller Fisher syndrome 2 (0.01) 11 (0.04) 14 (0.03) 0 51 (0.06) 13 (0.00) 94 (0.02)
Mitral valve incompetence 8 (0.04) 13 (0.05) 4 (0.01) 0 45 (0.05) 17 (0.01) 99 (0.02)
Mobility decreased 36 (0.20) 114 (0.45) 496 (1.01) 2 (0.43) 399 (0.46) 442 (0.13) 1545 (0.30)
Monoparesis 4 (0.02) 24 (0.09) 56 (0.11) 0 91 (0.11) 185 (0.06) 372 (0.07)
Monoplegia 8 (0.04) 30 (0.12) 125 (0.26) 0 127 (0.15) 451 (0.13) 765 (0.15)
Mood altered 3 (0.02) 7 (0.03) 23 (0.05) 0 13 (0.02) 113 (0.03) 162 (0.03)
Mood swings 1 (0.01) 6 (0.02) 41 (0.08) 1 (0.22) 9 (0.01) 167 (0.05) 227 (0.04)
Morning sickness 0 0 4 (0.01) 0 4 (0.00) 49 (0.01) 57 (0.01)
Motion sickness 0 3 (0.01) 41 (0.08) 0 7 (0.01) 140 (0.04) 193 (0.04)
Motor dysfunction 12 (0.07) 24 (0.09) 61 (0.12) 0 121 (0.14) 69 (0.02) 298 (0.06)
Mouth haemorrhage 9 (0.05) 31 (0.12) 7 (0.01) 0 47 (0.05) 61 (0.02) 170 (0.03)
Mouth swelling 3 (0.02) 42 (0.17) 21 (0.04) 0 53 (0.06) 179 (0.05) 301 (0.06)
Mouth ulceration 1 (0.01) 8 (0.03) 79 (0.16) 0 27 (0.03) 559 (0.17) 675 (0.13)
Movement disorder 12 (0.07) 43 (0.17) 186 (0.38) 0 288 (0.34) 320 (0.10) 896 (0.17)
Multiple organ dysfunction syndrome 206 (1.13) 32 (0.13) 1 (0.00) 0 19 (0.02) 11 (0.00) 309 (0.06)
Multiple sclerosis 1 (0.01) 7 (0.03) 78 (0.16) 1 (0.22) 88 (0.10) 239 (0.07) 428 (0.08)
Multiple sclerosis relapse 1 (0.01) 5 (0.02) 59 (0.12) 0 84 (0.10) 196 (0.06) 348 (0.07)
Muscle atrophy 2 (0.01) 10 (0.04) 37 (0.08) 0 21 (0.02) 38 (0.01) 112 (0.02)
Muscle contractions involuntary 0 9 (0.04) 60 (0.12) 0 37 (0.04) 79 (0.02) 188 (0.04)
Muscle contracture 0 8 (0.03) 10 (0.02) 0 9 (0.01) 27 (0.01) 60 (0.01)
Muscle disorder 1 (0.01) 4 (0.02) 21 (0.04) 0 18 (0.02) 23 (0.01) 71 (0.01)
Muscle fatigue 1 (0.01) 9 (0.04) 215 (0.44) 0 32 (0.04) 926 (0.28) 1188 (0.23)
Muscle injury 0 5 (0.02) 19 (0.04) 0 7 (0.01) 58 (0.02) 89 (0.02)
Muscle rigidity 7 (0.04) 13 (0.05) 50 (0.10) 0 45 (0.05) 99 (0.03) 218 (0.04)
Muscle rupture 0 1 (0.00) 6 (0.01) 0 3 (0.00) 55 (0.02) 65 (0.01)
Muscle spasms 17 (0.09) 179 (0.71) 945 (1.93) 6 (1.30) 627 (0.73) 3764 (1.12) 5597 (1.09)
Muscle spasticity 2 (0.01) 4 (0.02) 26 (0.05) 0 24 (0.03) 38 (0.01) 94 (0.02)
Muscle strain 0 9 (0.04) 21 (0.04) 0 19 (0.02) 76 (0.02) 125 (0.02)
Muscle swelling 0 0 13 (0.03) 0 11 (0.01) 58 (0.02) 83 (0.02)
Muscle tightness 2 (0.01) 29 (0.11) 90 (0.18) 2 (0.43) 95 (0.11) 295 (0.09) 523 (0.10)
Muscle twitching 5 (0.03) 39 (0.15) 232 (0.47) 1 (0.22) 173 (0.20) 598 (0.18) 1060 (0.21)
Muscular weakness 61 (0.33) 275 (1.08) 1410 (2.88) 2 (0.43) 1335 (1.55) 2531 (0.75) 5748 (1.12)
Musculoskeletal chest pain 3 (0.02) 45 (0.18) 121 (0.25) 0 115 (0.13) 542 (0.16) 838 (0.16)
Musculoskeletal discomfort 2 (0.01) 13 (0.05) 58 (0.12) 0 62 (0.07) 206 (0.06) 351 (0.07)
Musculoskeletal disorder 2 (0.01) 12 (0.05) 60 (0.12) 0 35 (0.04) 53 (0.02) 170 (0.03)
Musculoskeletal pain 5 (0.03) 26 (0.10) 122 (0.25) 1 (0.22) 176 (0.20) 564 (0.17) 905 (0.18)
Musculoskeletal stiffness 11 (0.06) 65 (0.26) 872 (1.78) 0 320 (0.37) 2604 (0.77) 3907 (0.76)
Myalgia 146 (0.80) 645 (2.54) 10050 (20.56) 12 (2.61) 2792 (3.25) 28560 (8.50) 42400 (8.24)
Myasthenia gravis 3 (0.02) 11 (0.04) 35 (0.07) 0 64 (0.07) 78 (0.02) 195 (0.04)
Mydriasis 9 (0.05) 11 (0.04) 9 (0.02) 0 33 (0.04) 52 (0.02) 124 (0.02)
Myelitis 4 (0.02) 9 (0.04) 50 (0.10) 1 (0.22) 188 (0.22) 51 (0.02) 308 (0.06)
Myelitis transverse 1 (0.01) 24 (0.09) 129 (0.26) 0 148 (0.17) 77 (0.02) 387 (0.08)
Myocardial infarction 738 (4.05) 869 (3.43) 75 (0.15) 0 914 (1.06) 507 (0.15) 3211 (0.62)
Myocardial injury 1 (0.01) 18 (0.07) 5 (0.01) 0 28 (0.03) 22 (0.01) 79 (0.02)
Myocardial ischaemia 95 (0.52) 12 (0.05) 3 (0.01) 0 49 (0.06) 21 (0.01) 194 (0.04)
Myocardial necrosis marker increased 1 (0.01) 10 (0.04) 1 (0.00) 0 43 (0.05) 13 (0.00) 80 (0.02)
Myocardial strain imaging 5 (0.03) 35 (0.14) 0 0 25 (0.03) 1 (0.00) 75 (0.01)
Myocarditis 110 (0.60) 771 (3.04) 196 (0.40) 3 (0.65) 3992 (4.65) 2352 (0.70) 7543 (1.47)
Myoclonus 3 (0.02) 11 (0.04) 26 (0.05) 0 55 (0.06) 74 (0.02) 175 (0.03)
Myopathy 2 (0.01) 3 (0.01) 13 (0.03) 0 15 (0.02) 17 (0.01) 53 (0.01)
Myositis 5 (0.03) 16 (0.06) 48 (0.10) 0 82 (0.10) 85 (0.03) 241 (0.05)
Narcolepsy 0 2 (0.01) 18 (0.04) 0 4 (0.00) 52 (0.02) 80 (0.02)
Nasal congestion 7 (0.04) 24 (0.09) 146 (0.30) 0 100 (0.12) 680 (0.20) 961 (0.19)
Nasal discomfort 0 4 (0.02) 20 (0.04) 0 14 (0.02) 116 (0.03) 154 (0.03)
Nasal dryness 0 5 (0.02) 13 (0.03) 0 4 (0.00) 47 (0.01) 69 (0.01)
Nasal oedema 0 5 (0.02) 3 (0.01) 0 9 (0.01) 35 (0.01) 53 (0.01)
Nasopharyngitis 57 (0.31) 37 (0.15) 276 (0.56) 1 (0.22) 319 (0.37) 1930 (0.57) 2638 (0.51)
Nausea 309 (1.69) 1036 (4.09) 8213 (16.80) 13 (2.83) 4762 (5.55) 36339 (10.81) 51014 (9.91)
Near death experience 0 31 (0.12) 3 (0.01) 0 14 (0.02) 100 (0.03) 169 (0.03)
Neck mass 3 (0.02) 4 (0.02) 7 (0.01) 0 13 (0.02) 51 (0.02) 78 (0.02)
Neck pain 18 (0.10) 159 (0.63) 957 (1.96) 2 (0.43) 627 (0.73) 3743 (1.11) 5555 (1.08)
Neoplasm malignant 16 (0.09) 9 (0.04) 5 (0.01) 0 17 (0.02) 90 (0.03) 150 (0.03)
Nephritis 1 (0.01) 3 (0.01) 0 0 25 (0.03) 42 (0.01) 72 (0.01)
Nephrolithiasis 1 (0.01) 9 (0.04) 7 (0.01) 0 61 (0.07) 127 (0.04) 215 (0.04)
Nephrotic syndrome 2 (0.01) 10 (0.04) 6 (0.01) 0 121 (0.14) 69 (0.02) 210 (0.04)
Nerve compression 1 (0.01) 3 (0.01) 26 (0.05) 0 7 (0.01) 69 (0.02) 108 (0.02)
Nerve injury 1 (0.01) 18 (0.07) 149 (0.30) 0 41 (0.05) 165 (0.05) 385 (0.07)
Nervous system disorder 28 (0.15) 37 (0.15) 156 (0.32) 1 (0.22) 150 (0.17) 137 (0.04) 534 (0.10)
Nervousness 3 (0.02) 20 (0.08) 117 (0.24) 0 50 (0.06) 595 (0.18) 792 (0.15)
Neuralgia 4 (0.02) 50 (0.20) 599 (1.23) 1 (0.22) 332 (0.39) 1441 (0.43) 2451 (0.48)
Neuralgic amyotrophy 1 (0.01) 2 (0.01) 65 (0.13) 0 44 (0.05) 69 (0.02) 183 (0.04)
Neuritis 0 2 (0.01) 21 (0.04) 0 57 (0.07) 45 (0.01) 129 (0.03)
Neurological symptom 14 (0.08) 48 (0.19) 112 (0.23) 0 145 (0.17) 136 (0.04) 467 (0.09)
Neuromyelitis optica spectrum disorder 1 (0.01) 4 (0.02) 14 (0.03) 0 31 (0.04) 8 (0.00) 63 (0.01)
Neuropathy peripheral 0 23 (0.09) 251 (0.51) 0 153 (0.18) 1237 (0.37) 1709 (0.33)
Neutropenia 2 (0.01) 30 (0.12) 4 (0.01) 0 59 (0.07) 140 (0.04) 243 (0.05)
Night sweats 5 (0.03) 39 (0.15) 249 (0.51) 1 (0.22) 145 (0.17) 1704 (0.51) 2153 (0.42)
Nightmare 2 (0.01) 12 (0.05) 76 (0.16) 1 (0.22) 20 (0.02) 409 (0.12) 523 (0.10)
Nipple pain 1 (0.01) 0 5 (0.01) 0 3 (0.00) 52 (0.02) 61 (0.01)
Nodule 3 (0.02) 13 (0.05) 30 (0.06) 0 46 (0.05) 92 (0.03) 188 (0.04)
Non-cardiac chest pain 0 1 (0.00) 8 (0.02) 0 10 (0.01) 51 (0.02) 72 (0.01)
Noninfective encephalitis 2 (0.01) 7 (0.03) 9 (0.02) 1 (0.22) 12 (0.01) 26 (0.01) 63 (0.01)
Nuchal rigidity 1 (0.01) 3 (0.01) 19 (0.04) 0 19 (0.02) 63 (0.02) 105 (0.02)
Nystagmus 1 (0.01) 10 (0.04) 23 (0.05) 0 69 (0.08) 39 (0.01) 152 (0.03)
Obstructive airways disorder 5 (0.03) 40 (0.16) 2 (0.00) 0 35 (0.04) 37 (0.01) 123 (0.02)
Occipital neuralgia 0 2 (0.01) 19 (0.04) 0 4 (0.00) 39 (0.01) 64 (0.01)
Ocular discomfort 2 (0.01) 9 (0.04) 50 (0.10) 1 (0.22) 72 (0.08) 141 (0.04) 276 (0.05)
Ocular hyperaemia 2 (0.01) 26 (0.10) 59 (0.12) 1 (0.22) 94 (0.11) 492 (0.15) 689 (0.13)
Odynophagia 1 (0.01) 9 (0.04) 20 (0.04) 1 (0.22) 44 (0.05) 174 (0.05) 254 (0.05)
Oedema 28 (0.15) 54 (0.21) 57 (0.12) 1 (0.22) 242 (0.28) 344 (0.10) 754 (0.15)
Oedema peripheral 49 (0.27) 117 (0.46) 170 (0.35) 0 372 (0.43) 630 (0.19) 1385 (0.27)
Off label use 27 (0.15) 47 (0.19) 153 (0.31) 1 (0.22) 132 (0.15) 1994 (0.59) 2379 (0.46)
Oligomenorrhoea 0 3 (0.01) 51 (0.10) 0 13 (0.02) 178 (0.05) 245 (0.05)
Ophthalmic herpes zoster 0 3 (0.01) 26 (0.05) 0 67 (0.08) 319 (0.09) 420 (0.08)
Ophthalmic migraine 0 0 14 (0.03) 0 15 (0.02) 49 (0.01) 79 (0.02)
Ophthalmic vein thrombosis 2 (0.01) 7 (0.03) 14 (0.03) 0 40 (0.05) 64 (0.02) 129 (0.03)
Ophthalmoplegia 0 3 (0.01) 12 (0.02) 0 28 (0.03) 25 (0.01) 72 (0.01)
Optic ischaemic neuropathy 0 1 (0.00) 47 (0.10) 0 43 (0.05) 49 (0.01) 144 (0.03)
Optic neuritis 0 3 (0.01) 95 (0.19) 0 155 (0.18) 149 (0.04) 410 (0.08)
Oral blood blister 0 10 (0.04) 4 (0.01) 0 13 (0.02) 25 (0.01) 54 (0.01)
Oral candidiasis 5 (0.03) 3 (0.01) 7 (0.01) 0 11 (0.01) 55 (0.02) 83 (0.02)
Oral discomfort 1 (0.01) 15 (0.06) 34 (0.07) 0 34 (0.04) 169 (0.05) 253 (0.05)
Oral disorder 1 (0.01) 3 (0.01) 5 (0.01) 0 18 (0.02) 33 (0.01) 62 (0.01)
Oral herpes 1 (0.01) 11 (0.04) 78 (0.16) 0 31 (0.04) 621 (0.18) 745 (0.14)
Oral mucosal blistering 0 5 (0.02) 18 (0.04) 0 21 (0.02) 45 (0.01) 91 (0.02)
Oral pain 2 (0.01) 9 (0.04) 55 (0.11) 1 (0.22) 27 (0.03) 303 (0.09) 405 (0.08)
Oral pruritus 0 13 (0.05) 8 (0.02) 0 33 (0.04) 71 (0.02) 128 (0.02)
Organising pneumonia 4 (0.02) 4 (0.02) 3 (0.01) 0 29 (0.03) 13 (0.00) 55 (0.01)
Oropharyngeal blistering 0 1 (0.00) 1 (0.00) 0 5 (0.01) 61 (0.02) 70 (0.01)
Oropharyngeal discomfort 1 (0.01) 34 (0.13) 24 (0.05) 0 260 (0.30) 560 (0.17) 903 (0.18)
Oropharyngeal pain 41 (0.22) 131 (0.52) 760 (1.55) 2 (0.43) 569 (0.66) 4724 (1.41) 6259 (1.22)
Orthopnoea 3 (0.02) 12 (0.05) 4 (0.01) 0 32 (0.04) 20 (0.01) 73 (0.01)
Orthostatic hypotension 1 (0.01) 9 (0.04) 29 (0.06) 0 43 (0.05) 70 (0.02) 160 (0.03)
Osteoarthritis 1 (0.01) 3 (0.01) 68 (0.14) 0 28 (0.03) 109 (0.03) 214 (0.04)
Ovarian cyst 1 (0.01) 4 (0.02) 16 (0.03) 0 24 (0.03) 38 (0.01) 84 (0.02)
Overdose 3 (0.02) 2 (0.01) 9 (0.02) 0 16 (0.02) 68 (0.02) 101 (0.02)
Ovulation pain 0 0 8 (0.02) 0 2 (0.00) 80 (0.02) 91 (0.02)
Oxygen saturation decreased 199 (1.09) 166 (0.65) 63 (0.13) 0 562 (0.65) 643 (0.19) 1774 (0.34)
Pain 182 (1.00) 675 (2.66) 4258 (8.71) 12 (2.61) 2480 (2.89) 18929 (5.63) 26772 (5.20)
Pain in extremity 139 (0.76) 877 (3.46) 4883 (9.99) 12 (2.61) 2550 (2.97) 23676 (7.04) 32377 (6.29)
Pain in jaw 5 (0.03) 39 (0.15) 164 (0.34) 0 127 (0.15) 687 (0.20) 1039 (0.20)
Pain of skin 2 (0.01) 14 (0.06) 206 (0.42) 0 49 (0.06) 907 (0.27) 1184 (0.23)
Painful respiration 5 (0.03) 30 (0.12) 29 (0.06) 0 94 (0.11) 87 (0.03) 254 (0.05)
Palatal oedema 0 13 (0.05) 2 (0.00) 0 16 (0.02) 68 (0.02) 100 (0.02)
Pallor 39 (0.21) 123 (0.49) 101 (0.21) 1 (0.22) 268 (0.31) 785 (0.23) 1368 (0.27)
Palpitations 32 (0.18) 541 (2.13) 1464 (3.00) 4 (0.87) 2117 (2.47) 7010 (2.09) 11277 (2.19)
Pancreatitis 10 (0.05) 33 (0.13) 11 (0.02) 0 166 (0.19) 104 (0.03) 331 (0.06)
Pancreatitis acute 9 (0.05) 38 (0.15) 2 (0.00) 0 241 (0.28) 56 (0.02) 356 (0.07)
Pancytopenia 16 (0.09) 34 (0.13) 3 (0.01) 0 83 (0.10) 26 (0.01) 179 (0.03)
Panic attack 3 (0.02) 36 (0.14) 124 (0.25) 0 138 (0.16) 411 (0.12) 731 (0.14)
Panic reaction 1 (0.01) 10 (0.04) 22 (0.05) 0 16 (0.02) 74 (0.02) 125 (0.02)
Papilloedema 1 (0.01) 5 (0.02) 25 (0.05) 0 30 (0.03) 36 (0.01) 102 (0.02)
Papule 0 1 (0.00) 14 (0.03) 1 (0.22) 13 (0.02) 123 (0.04) 154 (0.03)
Paraesthesia 22 (0.12) 536 (2.11) 2149 (4.40) 2 (0.43) 2930 (3.41) 9838 (2.93) 15648 (3.04)
Paraesthesia oral 1 (0.01) 113 (0.45) 149 (0.30) 0 308 (0.36) 1275 (0.38) 1861 (0.36)
Paralysis 28 (0.15) 116 (0.46) 237 (0.48) 1 (0.22) 324 (0.38) 715 (0.21) 1500 (0.29)
Paranasal sinus discomfort 2 (0.01) 3 (0.01) 21 (0.04) 0 9 (0.01) 86 (0.03) 122 (0.02)
Paranoia 3 (0.02) 8 (0.03) 13 (0.03) 0 21 (0.02) 44 (0.01) 90 (0.02)
Paraparesis 1 (0.01) 4 (0.02) 14 (0.03) 0 44 (0.05) 23 (0.01) 91 (0.02)
Paraplegia 0 9 (0.04) 16 (0.03) 0 24 (0.03) 16 (0.00) 70 (0.01)
Paresis 4 (0.02) 15 (0.06) 36 (0.07) 0 98 (0.11) 58 (0.02) 226 (0.04)
Parkinson's disease 6 (0.03) 3 (0.01) 10 (0.02) 0 16 (0.02) 64 (0.02) 104 (0.02)
Parosmia 1 (0.01) 12 (0.05) 149 (0.30) 0 43 (0.05) 336 (0.10) 542 (0.11)
Partial seizures 7 (0.04) 17 (0.07) 10 (0.02) 0 51 (0.06) 92 (0.03) 185 (0.04)
Pelvic pain 2 (0.01) 11 (0.04) 73 (0.15) 1 (0.22) 36 (0.04) 242 (0.07) 367 (0.07)
Pelvic venous thrombosis 4 (0.02) 35 (0.14) 5 (0.01) 0 55 (0.06) 25 (0.01) 131 (0.03)
Pemphigoid 7 (0.04) 9 (0.04) 23 (0.05) 0 50 (0.06) 115 (0.03) 208 (0.04)
Pemphigus 0 3 (0.01) 5 (0.01) 0 11 (0.01) 36 (0.01) 56 (0.01)
Periarthritis 0 1 (0.00) 242 (0.50) 0 16 (0.02) 414 (0.12) 675 (0.13)
Pericardial effusion 30 (0.16) 133 (0.52) 28 (0.06) 0 416 (0.48) 330 (0.10) 999 (0.19)
Pericarditis 17 (0.09) 316 (1.25) 149 (0.30) 0 1875 (2.18) 3097 (0.92) 5514 (1.07)
Periorbital oedema 0 3 (0.01) 4 (0.01) 0 19 (0.02) 54 (0.02) 82 (0.02)
Periorbital swelling 0 11 (0.04) 30 (0.06) 0 46 (0.05) 193 (0.06) 280 (0.05)
Peripheral artery occlusion 4 (0.02) 12 (0.05) 2 (0.00) 0 33 (0.04) 6 (0.00) 60 (0.01)
Peripheral artery thrombosis 13 (0.07) 60 (0.24) 11 (0.02) 0 97 (0.11) 45 (0.01) 232 (0.05)
Peripheral circulatory failure 5 (0.03) 3 (0.01) 1 (0.00) 0 33 (0.04) 14 (0.00) 61 (0.01)
Peripheral coldness 21 (0.12) 68 (0.27) 241 (0.49) 0 173 (0.20) 1216 (0.36) 1742 (0.34)
Peripheral embolism 4 (0.02) 19 (0.07) 9 (0.02) 0 40 (0.05) 20 (0.01) 95 (0.02)
Peripheral ischaemia 28 (0.15) 31 (0.12) 9 (0.02) 0 73 (0.09) 28 (0.01) 176 (0.03)
Peripheral sensory neuropathy 0 1 (0.00) 17 (0.03) 0 17 (0.02) 35 (0.01) 70 (0.01)
Peripheral swelling 59 (0.32) 447 (1.76) 1222 (2.50) 5 (1.09) 906 (1.06) 5991 (1.78) 8733 (1.70)
Peripheral vascular disorder 8 (0.04) 14 (0.06) 7 (0.01) 0 57 (0.07) 21 (0.01) 111 (0.02)
Peripheral venous disease 1 (0.01) 10 (0.04) 14 (0.03) 0 13 (0.02) 31 (0.01) 71 (0.01)
Peritonitis 6 (0.03) 14 (0.06) 2 (0.00) 0 28 (0.03) 7 (0.00) 60 (0.01)
Peroneal nerve palsy 1 (0.01) 5 (0.02) 35 (0.07) 0 19 (0.02) 23 (0.01) 85 (0.02)
Persistent postural-perceptual dizziness 0 0 14 (0.03) 0 5 (0.01) 34 (0.01) 53 (0.01)
Petechiae 23 (0.13) 138 (0.54) 56 (0.11) 0 441 (0.51) 450 (0.13) 1151 (0.22)
Petit mal epilepsy 1 (0.01) 12 (0.05) 9 (0.02) 0 26 (0.03) 106 (0.03) 157 (0.03)
Pharyngeal hypoaesthesia 0 8 (0.03) 13 (0.03) 0 22 (0.03) 69 (0.02) 117 (0.02)
Pharyngeal oedema 1 (0.01) 35 (0.14) 10 (0.02) 0 58 (0.07) 104 (0.03) 212 (0.04)
Pharyngeal paraesthesia 0 17 (0.07) 7 (0.01) 0 43 (0.05) 97 (0.03) 167 (0.03)
Pharyngeal swelling 4 (0.02) 257 (1.01) 91 (0.19) 0 242 (0.28) 639 (0.19) 1261 (0.24)
Pharyngitis 0 8 (0.03) 16 (0.03) 0 32 (0.04) 79 (0.02) 137 (0.03)
Phlebitis 0 17 (0.07) 21 (0.04) 0 70 (0.08) 222 (0.07) 333 (0.06)
Phlebitis superficial 0 3 (0.01) 2 (0.00) 0 8 (0.01) 51 (0.02) 65 (0.01)
Photophobia 8 (0.04) 54 (0.21) 392 (0.80) 0 219 (0.26) 1124 (0.33) 1812 (0.35)
Photopsia 2 (0.01) 20 (0.08) 69 (0.14) 0 59 (0.07) 346 (0.10) 501 (0.10)
Photosensitivity reaction 0 9 (0.04) 66 (0.14) 0 29 (0.03) 182 (0.05) 289 (0.06)
Physical deconditioning 6 (0.03) 3 (0.01) 3 (0.01) 0 63 (0.07) 39 (0.01) 128 (0.02)
Piloerection 0 2 (0.01) 12 (0.02) 0 7 (0.01) 102 (0.03) 124 (0.02)
Pityriasis rosea 0 2 (0.01) 6 (0.01) 0 4 (0.00) 86 (0.03) 98 (0.02)
Platelet count decreased 72 (0.39) 219 (0.86) 41 (0.08) 3 (0.65) 362 (0.42) 376 (0.11) 1132 (0.22)
Platelet count increased 3 (0.02) 11 (0.04) 8 (0.02) 1 (0.22) 22 (0.03) 38 (0.01) 87 (0.02)
Platelet count normal 4 (0.02) 21 (0.08) 4 (0.01) 0 35 (0.04) 21 (0.01) 85 (0.02)
Pleural effusion 54 (0.30) 125 (0.49) 23 (0.05) 1 (0.22) 363 (0.42) 74 (0.02) 719 (0.14)
Pleurisy 1 (0.01) 16 (0.06) 24 (0.05) 0 153 (0.18) 68 (0.02) 270 (0.05)
Pleuritic pain 1 (0.01) 45 (0.18) 15 (0.03) 0 80 (0.09) 31 (0.01) 179 (0.03)
Pleuropericarditis 0 6 (0.02) 0 0 36 (0.04) 8 (0.00) 51 (0.01)
Pneumonia 541 (2.97) 380 (1.50) 70 (0.14) 0 1318 (1.54) 737 (0.22) 3272 (0.64)
Pneumonia aspiration 137 (0.75) 31 (0.12) 5 (0.01) 0 61 (0.07) 19 (0.01) 282 (0.05)
Pneumonia bacterial 29 (0.16) 6 (0.02) 2 (0.00) 0 44 (0.05) 17 (0.01) 105 (0.02)
Pneumonia viral 12 (0.07) 4 (0.02) 3 (0.01) 0 24 (0.03) 20 (0.01) 66 (0.01)
Pneumonitis 31 (0.17) 40 (0.16) 11 (0.02) 0 115 (0.13) 60 (0.02) 272 (0.05)
Pneumothorax 13 (0.07) 21 (0.08) 4 (0.01) 0 75 (0.09) 37 (0.01) 168 (0.03)
Pollakiuria 9 (0.05) 17 (0.07) 66 (0.14) 0 54 (0.06) 288 (0.09) 443 (0.09)
Polyarthritis 0 1 (0.00) 29 (0.06) 0 46 (0.05) 118 (0.04) 195 (0.04)
Polymenorrhoea 0 5 (0.02) 111 (0.23) 2 (0.43) 37 (0.04) 702 (0.21) 857 (0.17)
Polymyalgia rheumatica 0 8 (0.03) 129 (0.26) 0 82 (0.10) 417 (0.12) 643 (0.12)
Polyneuropathy 3 (0.02) 15 (0.06) 42 (0.09) 0 119 (0.14) 130 (0.04) 327 (0.06)
Polyuria 5 (0.03) 14 (0.06) 12 (0.02) 0 34 (0.04) 37 (0.01) 104 (0.02)
Poor peripheral circulation 3 (0.02) 10 (0.04) 18 (0.04) 0 21 (0.02) 58 (0.02) 118 (0.02)
Poor quality sleep 5 (0.03) 7 (0.03) 125 (0.26) 0 24 (0.03) 627 (0.19) 791 (0.15)
Portal vein thrombosis 51 (0.28) 95 (0.37) 4 (0.01) 0 199 (0.23) 48 (0.01) 423 (0.08)
Post herpetic neuralgia 0 0 25 (0.05) 0 14 (0.02) 50 (0.01) 91 (0.02)
Post viral fatigue syndrome 0 0 98 (0.20) 0 5 (0.01) 129 (0.04) 234 (0.05)
Post-acute COVID-19 syndrome 0 5 (0.02) 15 (0.03) 0 15 (0.02) 27 (0.01) 67 (0.01)
Postmenopausal haemorrhage 0 5 (0.02) 31 (0.06) 0 33 (0.04) 1038 (0.31) 1108 (0.22)
Postural orthostatic tachycardia syndrome 0 4 (0.02) 45 (0.09) 0 33 (0.04) 46 (0.01) 134 (0.03)
Pregnancy 0 1 (0.00) 4 (0.01) 3 (0.65) 5 (0.01) 41 (0.01) 54 (0.01)
Premature baby 6 (0.03) 8 (0.03) 2 (0.00) 3 (0.65) 33 (0.04) 14 (0.00) 74 (0.01)
Premature labour 0 3 (0.01) 0 1 (0.22) 44 (0.05) 13 (0.00) 62 (0.01)
Premenstrual pain 0 0 22 (0.05) 0 1 (0.00) 148 (0.04) 171 (0.03)
Premenstrual syndrome 0 2 (0.01) 25 (0.05) 0 4 (0.00) 180 (0.05) 213 (0.04)
Presyncope 13 (0.07) 121 (0.48) 239 (0.49) 1 (0.22) 625 (0.73) 1779 (0.53) 2833 (0.55)
Product administered at inappropriate site 0 2 (0.01) 46 (0.09) 0 8 (0.01) 32 (0.01) 88 (0.02)
Product use issue 3 (0.02) 1 (0.00) 11 (0.02) 1 (0.22) 13 (0.02) 215 (0.06) 249 (0.05)
Productive cough 37 (0.20) 31 (0.12) 75 (0.15) 0 180 (0.21) 288 (0.09) 630 (0.12)
Proteinuria 0 5 (0.02) 7 (0.01) 0 40 (0.05) 35 (0.01) 88 (0.02)
Pruritus 15 (0.08) 342 (1.35) 862 (1.76) 4 (0.87) 1159 (1.35) 8329 (2.48) 10807 (2.10)
Psoriasis 2 (0.01) 10 (0.04) 66 (0.14) 0 45 (0.05) 298 (0.09) 423 (0.08)
Psoriatic arthropathy 0 0 27 (0.06) 0 3 (0.00) 103 (0.03) 135 (0.03)
Psychomotor hyperactivity 6 (0.03) 8 (0.03) 10 (0.02) 0 16 (0.02) 48 (0.01) 90 (0.02)
Psychotic disorder 0 17 (0.07) 21 (0.04) 0 53 (0.06) 49 (0.01) 143 (0.03)
Pulmonary artery thrombosis 13 (0.07) 18 (0.07) 0 0 18 (0.02) 1 (0.00) 55 (0.01)
Pulmonary congestion 20 (0.11) 11 (0.04) 9 (0.02) 0 47 (0.05) 163 (0.05) 272 (0.05)
Pulmonary embolism 787 (4.32) 3346 (13.20) 147 (0.30) 0 5202 (6.06) 1997 (0.59) 11683 (2.27)
Pulmonary fibrosis 14 (0.08) 10 (0.04) 10 (0.02) 0 33 (0.04) 35 (0.01) 111 (0.02)
Pulmonary haemorrhage 15 (0.08) 16 (0.06) 1 (0.00) 0 19 (0.02) 5 (0.00) 62 (0.01)
Pulmonary hypertension 12 (0.07) 18 (0.07) 2 (0.00) 0 37 (0.04) 22 (0.01) 108 (0.02)
Pulmonary infarction 12 (0.07) 92 (0.36) 4 (0.01) 0 111 (0.13) 36 (0.01) 274 (0.05)
Pulmonary mass 11 (0.06) 17 (0.07) 9 (0.02) 0 47 (0.05) 13 (0.00) 107 (0.02)
Pulmonary oedema 126 (0.69) 104 (0.41) 16 (0.03) 1 (0.22) 173 (0.20) 80 (0.02) 565 (0.11)
Pulmonary pain 1 (0.01) 37 (0.15) 97 (0.20) 0 72 (0.08) 260 (0.08) 472 (0.09)
Pulmonary thrombosis 43 (0.24) 223 (0.88) 16 (0.03) 0 279 (0.32) 90 (0.03) 677 (0.13)
Pulse abnormal 5 (0.03) 17 (0.07) 8 (0.02) 0 36 (0.04) 63 (0.02) 134 (0.03)
Pulse absent 39 (0.21) 17 (0.07) 0 0 15 (0.02) 15 (0.00) 91 (0.02)
Pulseless electrical activity 54 (0.30) 19 (0.07) 0 0 6 (0.01) 0 91 (0.02)
Puncture site pain 0 0 2 (0.00) 0 2 (0.00) 52 (0.02) 57 (0.01)
Pupils unequal 8 (0.04) 3 (0.01) 8 (0.02) 0 15 (0.02) 18 (0.01) 58 (0.01)
Purpura 12 (0.07) 27 (0.11) 22 (0.05) 0 144 (0.17) 197 (0.06) 412 (0.08)
Pustule 0 4 (0.02) 9 (0.02) 0 16 (0.02) 27 (0.01) 59 (0.01)
Pyelonephritis 6 (0.03) 6 (0.02) 4 (0.01) 0 66 (0.08) 45 (0.01) 134 (0.03)
Pyrexia 1063 (5.83) 1887 (7.44) 12389 (25.35) 31 (6.74) 8875 (10.34) 56015 (16.67) 80904 (15.71)
Q fever 0 3 (0.01) 14 (0.03) 0 3 (0.00) 97 (0.03) 117 (0.02)
Quadriparesis 5 (0.03) 15 (0.06) 10 (0.02) 0 41 (0.05) 2 (0.00) 77 (0.01)
Radiculitis brachial 0 0 30 (0.06) 0 8 (0.01) 20 (0.01) 58 (0.01)
Radiculopathy 0 4 (0.02) 15 (0.03) 0 51 (0.06) 19 (0.01) 91 (0.02)
Rales 20 (0.11) 4 (0.02) 4 (0.01) 0 24 (0.03) 21 (0.01) 81 (0.02)
Rash 38 (0.21) 420 (1.66) 986 (2.02) 5 (1.09) 1880 (2.19) 8420 (2.51) 11854 (2.30)
Rash erythematous 4 (0.02) 55 (0.22) 162 (0.33) 0 192 (0.22) 1705 (0.51) 2130 (0.41)
Rash macular 5 (0.03) 38 (0.15) 105 (0.21) 0 100 (0.12) 749 (0.22) 1005 (0.20)
Rash maculo-papular 0 12 (0.05) 7 (0.01) 0 75 (0.09) 166 (0.05) 264 (0.05)
Rash morbilliform 0 2 (0.01) 7 (0.01) 0 11 (0.01) 57 (0.02) 82 (0.02)
Rash papular 1 (0.01) 12 (0.05) 36 (0.07) 0 49 (0.06) 454 (0.14) 558 (0.11)
Rash pruritic 4 (0.02) 38 (0.15) 128 (0.26) 0 177 (0.21) 1718 (0.51) 2081 (0.40)
Rash vesicular 0 7 (0.03) 22 (0.05) 0 38 (0.04) 142 (0.04) 212 (0.04)
Raynaud's phenomenon 1 (0.01) 2 (0.01) 26 (0.05) 0 15 (0.02) 172 (0.05) 218 (0.04)
Rectal haemorrhage 17 (0.09) 21 (0.08) 15 (0.03) 1 (0.22) 116 (0.14) 318 (0.09) 503 (0.10)
Red blood cell count decreased 8 (0.04) 9 (0.04) 4 (0.01) 1 (0.22) 27 (0.03) 15 (0.00) 68 (0.01)
Red blood cell sedimentation rate increased 2 (0.01) 3 (0.01) 20 (0.04) 0 43 (0.05) 41 (0.01) 114 (0.02)
Renal colic 1 (0.01) 1 (0.00) 5 (0.01) 0 33 (0.04) 31 (0.01) 71 (0.01)
Renal disorder 15 (0.08) 19 (0.07) 23 (0.05) 0 59 (0.07) 31 (0.01) 159 (0.03)
Renal failure 155 (0.85) 108 (0.43) 17 (0.03) 0 154 (0.18) 75 (0.02) 576 (0.11)
Renal impairment 30 (0.16) 28 (0.11) 20 (0.04) 0 82 (0.10) 126 (0.04) 320 (0.06)
Renal infarct 12 (0.07) 24 (0.09) 9 (0.02) 0 55 (0.06) 13 (0.00) 123 (0.02)
Renal pain 4 (0.02) 26 (0.10) 196 (0.40) 1 (0.22) 106 (0.12) 902 (0.27) 1239 (0.24)
Renal vein thrombosis 5 (0.03) 16 (0.06) 3 (0.01) 0 19 (0.02) 5 (0.00) 51 (0.01)
Respiration abnormal 18 (0.10) 25 (0.10) 17 (0.03) 0 73 (0.09) 129 (0.04) 275 (0.05)
Respiratory arrest 210 (1.15) 81 (0.32) 3 (0.01) 0 44 (0.05) 64 (0.02) 452 (0.09)
Respiratory disorder 55 (0.30) 65 (0.26) 197 (0.40) 0 135 (0.16) 143 (0.04) 616 (0.12)
Respiratory distress 112 (0.61) 113 (0.45) 31 (0.06) 1 (0.22) 496 (0.58) 1140 (0.34) 2005 (0.39)
Respiratory failure 329 (1.80) 152 (0.60) 9 (0.02) 0 246 (0.29) 58 (0.02) 857 (0.17)
Respiratory rate decreased 5 (0.03) 7 (0.03) 5 (0.01) 0 10 (0.01) 34 (0.01) 66 (0.01)
Respiratory rate increased 15 (0.08) 26 (0.10) 19 (0.04) 0 56 (0.07) 139 (0.04) 265 (0.05)
Respiratory symptom 5 (0.03) 12 (0.05) 11 (0.02) 0 32 (0.04) 53 (0.02) 116 (0.02)
Respiratory tract congestion 16 (0.09) 8 (0.03) 17 (0.03) 0 88 (0.10) 28 (0.01) 165 (0.03)
Respiratory tract infection 11 (0.06) 5 (0.02) 2 (0.00) 0 22 (0.03) 56 (0.02) 108 (0.02)
Respiratory tract oedema 0 18 (0.07) 1 (0.00) 0 12 (0.01) 35 (0.01) 71 (0.01)
Restless legs syndrome 0 9 (0.04) 78 (0.16) 0 20 (0.02) 346 (0.10) 455 (0.09)
Restlessness 25 (0.14) 25 (0.10) 86 (0.18) 0 142 (0.17) 542 (0.16) 835 (0.16)
Resuscitation 56 (0.31) 32 (0.13) 0 0 18 (0.02) 2 (0.00) 112 (0.02)
Retching 8 (0.04) 31 (0.12) 71 (0.15) 0 100 (0.12) 321 (0.10) 543 (0.11)
Retinal artery occlusion 0 2 (0.01) 99 (0.20) 0 55 (0.06) 92 (0.03) 253 (0.05)
Retinal detachment 0 1 (0.00) 39 (0.08) 0 98 (0.11) 85 (0.03) 228 (0.04)
Retinal haemorrhage 0 2 (0.01) 22 (0.05) 0 13 (0.02) 81 (0.02) 121 (0.02)
Retinal migraine 0 0 10 (0.02) 0 5 (0.01) 85 (0.03) 100 (0.02)
Retinal tear 0 1 (0.00) 12 (0.02) 0 17 (0.02) 44 (0.01) 78 (0.02)
Retinal vascular thrombosis 2 (0.01) 2 (0.01) 37 (0.08) 0 19 (0.02) 30 (0.01) 91 (0.02)
Retinal vein occlusion 0 7 (0.03) 151 (0.31) 0 47 (0.05) 315 (0.09) 524 (0.10)
Retinal vein thrombosis 1 (0.01) 3 (0.01) 48 (0.10) 0 9 (0.01) 90 (0.03) 153 (0.03)
Rhabdomyolysis 13 (0.07) 46 (0.18) 17 (0.03) 0 178 (0.21) 74 (0.02) 337 (0.07)
Rheumatic disorder 0 3 (0.01) 19 (0.04) 0 19 (0.02) 45 (0.01) 90 (0.02)
Rheumatoid arthritis 7 (0.04) 9 (0.04) 199 (0.41) 0 70 (0.08) 768 (0.23) 1069 (0.21)
Rhinalgia 0 1 (0.00) 16 (0.03) 0 2 (0.00) 43 (0.01) 63 (0.01)
Rhinitis 6 (0.03) 10 (0.04) 34 (0.07) 0 38 (0.04) 122 (0.04) 212 (0.04)
Rhinorrhoea 16 (0.09) 37 (0.15) 237 (0.48) 0 202 (0.24) 1747 (0.52) 2253 (0.44)
Rib fracture 7 (0.04) 7 (0.03) 4 (0.01) 0 26 (0.03) 21 (0.01) 75 (0.01)
Road traffic accident 11 (0.06) 12 (0.05) 3 (0.01) 0 44 (0.05) 27 (0.01) 104 (0.02)
Rosacea 0 1 (0.00) 9 (0.02) 0 4 (0.00) 41 (0.01) 55 (0.01)
Rotator cuff syndrome 0 1 (0.00) 57 (0.12) 0 11 (0.01) 111 (0.03) 181 (0.04)
SARS-CoV-2 antibody test negative 1 (0.01) 3 (0.01) 4 (0.01) 0 4 (0.00) 41 (0.01) 54 (0.01)
SARS-CoV-2 test 5 (0.03) 16 (0.06) 5 (0.01) 0 25 (0.03) 23 (0.01) 74 (0.01)
SARS-CoV-2 test negative 12 (0.07) 29 (0.11) 57 (0.12) 0 74 (0.09) 38 (0.01) 212 (0.04)
SARS-CoV-2 test positive 150 (0.82) 40 (0.16) 17 (0.03) 0 398 (0.46) 603 (0.18) 1247 (0.24)
Salivary hypersecretion 3 (0.02) 11 (0.04) 23 (0.05) 0 28 (0.03) 93 (0.03) 160 (0.03)
Sarcoidosis 2 (0.01) 6 (0.02) 18 (0.04) 0 31 (0.04) 66 (0.02) 127 (0.02)
Scab 0 1 (0.00) 15 (0.03) 0 3 (0.00) 35 (0.01) 57 (0.01)
Scar 0 3 (0.01) 23 (0.05) 0 10 (0.01) 51 (0.02) 88 (0.02)
Sciatica 0 5 (0.02) 127 (0.26) 0 35 (0.04) 245 (0.07) 418 (0.08)
Scleritis 0 0 9 (0.02) 0 10 (0.01) 44 (0.01) 63 (0.01)
Screaming 1 (0.01) 1 (0.00) 18 (0.04) 0 9 (0.01) 33 (0.01) 63 (0.01)
Seasonal allergy 1 (0.01) 2 (0.01) 22 (0.05) 0 5 (0.01) 146 (0.04) 176 (0.03)
Secretion discharge 9 (0.05) 11 (0.04) 16 (0.03) 0 18 (0.02) 46 (0.01) 102 (0.02)
Seizure 154 (0.84) 508 (2.00) 335 (0.69) 3 (0.65) 1503 (1.75) 3719 (1.11) 6411 (1.25)
Seizure like phenomena 9 (0.05) 8 (0.03) 6 (0.01) 0 28 (0.03) 97 (0.03) 152 (0.03)
Sensation of foreign body 1 (0.01) 55 (0.22) 25 (0.05) 0 143 (0.17) 235 (0.07) 469 (0.09)
Sense of oppression 3 (0.02) 4 (0.02) 26 (0.05) 1 (0.22) 26 (0.03) 42 (0.01) 105 (0.02)
Sensitive skin 0 6 (0.02) 99 (0.20) 0 120 (0.14) 758 (0.23) 989 (0.19)
Sensory disturbance 0 28 (0.11) 141 (0.29) 0 362 (0.42) 319 (0.09) 874 (0.17)
Sensory loss 2 (0.01) 45 (0.18) 145 (0.30) 0 135 (0.16) 205 (0.06) 548 (0.11)
Sepsis 254 (1.39) 139 (0.55) 24 (0.05) 0 338 (0.39) 99 (0.03) 919 (0.18)
Septic shock 147 (0.81) 42 (0.17) 0 0 48 (0.06) 7 (0.00) 258 (0.05)
Severe acute respiratory syndrome 9 (0.05) 1 (0.00) 0 0 39 (0.05) 17 (0.01) 67 (0.01)
Shock 69 (0.38) 65 (0.26) 15 (0.03) 0 64 (0.07) 187 (0.06) 445 (0.09)
Shoulder injury related to vaccine administration 0 0 78 (0.16) 0 3 (0.00) 90 (0.03) 171 (0.03)
Sinus bradycardia 1 (0.01) 9 (0.04) 6 (0.01) 0 28 (0.03) 19 (0.01) 68 (0.01)
Sinus congestion 0 7 (0.03) 24 (0.05) 0 14 (0.02) 125 (0.04) 173 (0.03)
Sinus disorder 1 (0.01) 4 (0.02) 9 (0.02) 0 3 (0.00) 40 (0.01) 58 (0.01)
Sinus headache 0 3 (0.01) 102 (0.21) 0 14 (0.02) 844 (0.25) 964 (0.19)
Sinus pain 0 12 (0.05) 94 (0.19) 1 (0.22) 16 (0.02) 586 (0.17) 712 (0.14)
Sinus tachycardia 9 (0.05) 36 (0.14) 32 (0.07) 0 167 (0.19) 149 (0.04) 402 (0.08)
Sinusitis 5 (0.03) 11 (0.04) 91 (0.19) 0 63 (0.07) 414 (0.12) 591 (0.11)
Sjogren's syndrome 0 4 (0.02) 10 (0.02) 0 9 (0.01) 54 (0.02) 82 (0.02)
Skin burning sensation 1 (0.01) 31 (0.12) 126 (0.26) 0 85 (0.10) 566 (0.17) 816 (0.16)
Skin discolouration 15 (0.08) 54 (0.21) 65 (0.13) 1 (0.22) 116 (0.14) 311 (0.09) 586 (0.11)
Skin disorder 5 (0.03) 22 (0.09) 387 (0.79) 0 62 (0.07) 150 (0.04) 635 (0.12)
Skin erosion 0 1 (0.00) 12 (0.02) 0 6 (0.01) 51 (0.02) 70 (0.01)
Skin exfoliation 3 (0.02) 10 (0.04) 50 (0.10) 1 (0.22) 42 (0.05) 210 (0.06) 322 (0.06)
Skin haemorrhage 4 (0.02) 9 (0.04) 15 (0.03) 0 32 (0.04) 52 (0.02) 120 (0.02)
Skin infection 1 (0.01) 4 (0.02) 12 (0.02) 0 12 (0.01) 49 (0.01) 80 (0.02)
Skin irritation 0 5 (0.02) 26 (0.05) 0 9 (0.01) 154 (0.05) 194 (0.04)
Skin laceration 0 9 (0.04) 11 (0.02) 0 38 (0.04) 32 (0.01) 98 (0.02)
Skin lesion 4 (0.02) 9 (0.04) 23 (0.05) 0 31 (0.04) 89 (0.03) 161 (0.03)
Skin mass 0 0 8 (0.02) 0 11 (0.01) 70 (0.02) 90 (0.02)
Skin odour abnormal 0 3 (0.01) 11 (0.02) 0 1 (0.00) 38 (0.01) 54 (0.01)
Skin reaction 2 (0.01) 16 (0.06) 36 (0.07) 0 43 (0.05) 293 (0.09) 390 (0.08)
Skin sensitisation 0 1 (0.00) 24 (0.05) 0 0 94 (0.03) 119 (0.02)
Skin swelling 1 (0.01) 2 (0.01) 12 (0.02) 0 17 (0.02) 98 (0.03) 131 (0.03)
Skin temperature 0 0 11 (0.02) 0 2 (0.00) 144 (0.04) 157 (0.03)
Skin tightness 0 2 (0.01) 10 (0.02) 0 6 (0.01) 60 (0.02) 80 (0.02)
Skin ulcer 5 (0.03) 4 (0.02) 19 (0.04) 0 27 (0.03) 45 (0.01) 104 (0.02)
Skin warm 3 (0.02) 30 (0.12) 58 (0.12) 0 61 (0.07) 517 (0.15) 670 (0.13)
Sleep apnoea syndrome 4 (0.02) 5 (0.02) 13 (0.03) 0 17 (0.02) 35 (0.01) 75 (0.01)
Sleep deficit 0 3 (0.01) 27 (0.06) 0 6 (0.01) 51 (0.02) 88 (0.02)
Sleep disorder 7 (0.04) 59 (0.23) 336 (0.69) 1 (0.22) 164 (0.19) 748 (0.22) 1335 (0.26)
Sleep terror 0 3 (0.01) 10 (0.02) 0 2 (0.00) 52 (0.02) 67 (0.01)
Slow speech 4 (0.02) 7 (0.03) 27 (0.06) 0 29 (0.03) 46 (0.01) 115 (0.02)
Sluggishness 2 (0.01) 9 (0.04) 8 (0.02) 0 15 (0.02) 48 (0.01) 86 (0.02)
Sneezing 5 (0.03) 17 (0.07) 81 (0.17) 0 29 (0.03) 538 (0.16) 671 (0.13)
Somnolence 103 (0.56) 201 (0.79) 526 (1.08) 3 (0.65) 547 (0.64) 2624 (0.78) 4086 (0.79)
Speech disorder 29 (0.16) 142 (0.56) 197 (0.40) 1 (0.22) 446 (0.52) 327 (0.10) 1208 (0.23)
Spinal pain 3 (0.02) 15 (0.06) 96 (0.20) 0 66 (0.08) 310 (0.09) 500 (0.10)
Splenic infarction 13 (0.07) 19 (0.07) 4 (0.01) 0 69 (0.08) 19 (0.01) 135 (0.03)
Splenic vein thrombosis 11 (0.06) 24 (0.09) 3 (0.01) 0 23 (0.03) 9 (0.00) 75 (0.01)
Splenomegaly 3 (0.02) 9 (0.04) 5 (0.01) 0 55 (0.06) 22 (0.01) 102 (0.02)
Spontaneous haematoma 2 (0.01) 6 (0.02) 3 (0.01) 0 23 (0.03) 43 (0.01) 79 (0.02)
Sputum discoloured 4 (0.02) 3 (0.01) 2 (0.00) 0 26 (0.03) 21 (0.01) 58 (0.01)
Staphylococcal infection 7 (0.04) 7 (0.03) 4 (0.01) 0 24 (0.03) 46 (0.01) 96 (0.02)
Staring 5 (0.03) 4 (0.02) 8 (0.02) 0 19 (0.02) 19 (0.01) 56 (0.01)
Status epilepticus 18 (0.10) 49 (0.19) 13 (0.03) 0 60 (0.07) 104 (0.03) 248 (0.05)
Stevens-Johnson syndrome 5 (0.03) 11 (0.04) 2 (0.00) 0 35 (0.04) 52 (0.02) 111 (0.02)
Still's disease 0 6 (0.02) 4 (0.01) 0 38 (0.04) 11 (0.00) 61 (0.01)
Stillbirth 11 (0.06) 0 0 2 (0.43) 19 (0.02) 18 (0.01) 51 (0.01)
Stomatitis 2 (0.01) 13 (0.05) 24 (0.05) 0 28 (0.03) 137 (0.04) 209 (0.04)
Stress 0 15 (0.06) 72 (0.15) 0 33 (0.04) 197 (0.06) 323 (0.06)
Stress cardiomyopathy 5 (0.03) 26 (0.10) 1 (0.00) 0 69 (0.08) 6 (0.00) 113 (0.02)
Stridor 2 (0.01) 58 (0.23) 0 0 68 (0.08) 67 (0.02) 203 (0.04)
Subarachnoid haemorrhage 143 (0.78) 174 (0.69) 10 (0.02) 0 164 (0.19) 32 (0.01) 544 (0.11)
Subclavian vein thrombosis 7 (0.04) 26 (0.10) 4 (0.01) 0 38 (0.04) 36 (0.01) 113 (0.02)
Subdural haematoma 23 (0.13) 63 (0.25) 4 (0.01) 0 71 (0.08) 18 (0.01) 192 (0.04)
Sudden cardiac death 101 (0.55) 1 (0.00) 0 0 0 0 102 (0.02)
Sudden death 854 (4.68) 0 0 0 0 0 855 (0.17)
Sudden hearing loss 0 3 (0.01) 171 (0.35) 0 76 (0.09) 377 (0.11) 634 (0.12)
Suffocation feeling 0 27 (0.11) 9 (0.02) 0 23 (0.03) 34 (0.01) 93 (0.02)
Suicidal ideation 4 (0.02) 53 (0.21) 44 (0.09) 0 30 (0.03) 304 (0.09) 457 (0.09)
Suicide attempt 5 (0.03) 20 (0.08) 2 (0.00) 0 7 (0.01) 33 (0.01) 69 (0.01)
Superficial vein thrombosis 4 (0.02) 56 (0.22) 24 (0.05) 0 155 (0.18) 636 (0.19) 890 (0.17)
Superior sagittal sinus thrombosis 19 (0.10) 47 (0.19) 4 (0.01) 0 40 (0.05) 12 (0.00) 126 (0.02)
Suppressed lactation 0 3 (0.01) 9 (0.02) 0 3 (0.00) 55 (0.02) 70 (0.01)
Supraventricular extrasystoles 0 8 (0.03) 5 (0.01) 0 19 (0.02) 47 (0.01) 84 (0.02)
Supraventricular tachycardia 7 (0.04) 48 (0.19) 28 (0.06) 1 (0.22) 131 (0.15) 108 (0.03) 330 (0.06)
Surgery 6 (0.03) 12 (0.05) 3 (0.01) 0 26 (0.03) 10 (0.00) 62 (0.01)
Suspected COVID-19 62 (0.34) 17 (0.07) 52 (0.11) 0 121 (0.14) 1223 (0.36) 1530 (0.30)
Sweating fever 0 3 (0.01) 83 (0.17) 0 10 (0.01) 652 (0.19) 748 (0.15)
Swelling 19 (0.10) 165 (0.65) 443 (0.91) 1 (0.22) 464 (0.54) 3328 (0.99) 4450 (0.86)
Swelling face 8 (0.04) 188 (0.74) 216 (0.44) 0 457 (0.53) 1617 (0.48) 2530 (0.49)
Swelling of eyelid 0 14 (0.06) 27 (0.06) 2 (0.43) 42 (0.05) 221 (0.07) 308 (0.06)
Swollen tongue 6 (0.03) 282 (1.11) 97 (0.20) 0 347 (0.40) 875 (0.26) 1632 (0.32)
Syncope 193 (1.06) 673 (2.66) 551 (1.13) 9 (1.96) 2057 (2.40) 11065 (3.29) 14837 (2.88)
Synovial cyst 0 2 (0.01) 10 (0.02) 0 7 (0.01) 32 (0.01) 53 (0.01)
Synovitis 0 1 (0.00) 14 (0.03) 0 13 (0.02) 23 (0.01) 51 (0.01)
Systemic inflammatory response syndrome 17 (0.09) 27 (0.11) 1 (0.00) 0 61 (0.07) 36 (0.01) 153 (0.03)
Systemic lupus erythematosus 1 (0.01) 22 (0.09) 24 (0.05) 0 42 (0.05) 180 (0.05) 274 (0.05)
Tachyarrhythmia 2 (0.01) 13 (0.05) 7 (0.01) 0 22 (0.03) 35 (0.01) 82 (0.02)
Tachycardia 93 (0.51) 601 (2.37) 544 (1.11) 4 (0.87) 2183 (2.54) 3366 (1.00) 6925 (1.35)
Tachypnoea 49 (0.27) 46 (0.18) 13 (0.03) 0 211 (0.25) 140 (0.04) 506 (0.10)
Taste disorder 3 (0.02) 21 (0.08) 181 (0.37) 0 98 (0.11) 486 (0.14) 800 (0.16)
Tearfulness 0 4 (0.02) 20 (0.04) 0 2 (0.00) 112 (0.03) 138 (0.03)
Temperature intolerance 0 3 (0.01) 23 (0.05) 0 10 (0.01) 111 (0.03) 148 (0.03)
Temperature regulation disorder 0 3 (0.01) 18 (0.04) 0 10 (0.01) 59 (0.02) 92 (0.02)
Tenderness 8 (0.04) 20 (0.08) 148 (0.30) 0 104 (0.12) 1354 (0.40) 1653 (0.32)
Tendon pain 0 2 (0.01) 39 (0.08) 0 11 (0.01) 62 (0.02) 116 (0.02)
Tendon rupture 0 0 18 (0.04) 0 10 (0.01) 36 (0.01) 67 (0.01)
Tendonitis 0 4 (0.02) 73 (0.15) 0 12 (0.01) 133 (0.04) 223 (0.04)
Tension 1 (0.01) 6 (0.02) 13 (0.03) 0 11 (0.01) 88 (0.03) 123 (0.02)
Tension headache 1 (0.01) 16 (0.06) 209 (0.43) 0 90 (0.10) 1301 (0.39) 1622 (0.32)
Testicular pain 2 (0.01) 1 (0.00) 20 (0.04) 0 14 (0.02) 115 (0.03) 155 (0.03)
Tetany 0 3 (0.01) 3 (0.01) 0 20 (0.02) 30 (0.01) 59 (0.01)
Thalamic infarction 3 (0.02) 16 (0.06) 17 (0.03) 0 53 (0.06) 10 (0.00) 102 (0.02)
Thalamus haemorrhage 2 (0.01) 12 (0.05) 7 (0.01) 0 25 (0.03) 2 (0.00) 51 (0.01)
Therapeutic response unexpected 0 2 (0.01) 11 (0.02) 0 4 (0.00) 92 (0.03) 110 (0.02)
Therapy non-responder 1 (0.01) 0 3 (0.01) 0 10 (0.01) 413 (0.12) 427 (0.08)
Thermal burn 1 (0.01) 4 (0.02) 10 (0.02) 0 3 (0.00) 50 (0.01) 69 (0.01)
Thermal burns of eye 0 0 7 (0.01) 0 2 (0.00) 49 (0.01) 58 (0.01)
Thinking abnormal 2 (0.01) 6 (0.02) 26 (0.05) 0 25 (0.03) 54 (0.02) 117 (0.02)
Thirst 2 (0.01) 34 (0.13) 180 (0.37) 1 (0.22) 76 (0.09) 1152 (0.34) 1453 (0.28)
Throat irritation 6 (0.03) 86 (0.34) 54 (0.11) 0 202 (0.24) 619 (0.18) 978 (0.19)
Throat tightness 2 (0.01) 265 (1.05) 74 (0.15) 2 (0.43) 386 (0.45) 902 (0.27) 1672 (0.32)
Thrombectomy 11 (0.06) 36 (0.14) 5 (0.01) 0 24 (0.03) 1 (0.00) 78 (0.02)
Thrombocytopenia 393 (2.16) 906 (3.57) 82 (0.17) 0 1700 (1.98) 1311 (0.39) 4740 (0.92)
Thrombocytopenic purpura 5 (0.03) 22 (0.09) 0 0 72 (0.08) 18 (0.01) 125 (0.02)
Thrombocytosis 2 (0.01) 13 (0.05) 5 (0.01) 0 31 (0.04) 18 (0.01) 72 (0.01)
Thrombophlebitis 9 (0.05) 58 (0.23) 40 (0.08) 0 114 (0.13) 478 (0.14) 713 (0.14)
Thrombosis 414 (2.27) 1217 (4.80) 347 (0.71) 4 (0.87) 1657 (1.93) 3720 (1.11) 7611 (1.48)
Thrombosis in device 2 (0.01) 26 (0.10) 3 (0.01) 0 20 (0.02) 23 (0.01) 74 (0.01)
Thrombosis with thrombocytopenia syndrome 18 (0.10) 10 (0.04) 3 (0.01) 0 22 (0.03) 12 (0.00) 77 (0.01)
Thrombotic stroke 7 (0.04) 15 (0.06) 6 (0.01) 0 22 (0.03) 3 (0.00) 55 (0.01)
Thrombotic thrombocytopenic purpura 18 (0.10) 49 (0.19) 0 0 47 (0.05) 17 (0.01) 134 (0.03)
Thunderclap headache 1 (0.01) 5 (0.02) 14 (0.03) 0 27 (0.03) 37 (0.01) 84 (0.02)
Thyroid disorder 1 (0.01) 4 (0.02) 8 (0.02) 0 9 (0.01) 32 (0.01) 54 (0.01)
Thyroiditis 0 1 (0.00) 16 (0.03) 1 (0.22) 11 (0.01) 66 (0.02) 96 (0.02)
Thyroiditis subacute 0 0 6 (0.01) 0 28 (0.03) 63 (0.02) 97 (0.02)
Tic 0 2 (0.01) 16 (0.03) 0 17 (0.02) 25 (0.01) 60 (0.01)
Tinnitus 5 (0.03) 100 (0.39) 1689 (3.46) 5 (1.09) 438 (0.51) 3823 (1.14) 6104 (1.19)
Tongue biting 1 (0.01) 9 (0.04) 5 (0.01) 0 14 (0.02) 20 (0.01) 53 (0.01)
Tongue discolouration 0 1 (0.00) 14 (0.03) 0 9 (0.01) 39 (0.01) 64 (0.01)
Tongue discomfort 0 7 (0.03) 18 (0.04) 0 23 (0.03) 86 (0.03) 135 (0.03)
Tongue disorder 0 9 (0.04) 7 (0.01) 0 19 (0.02) 81 (0.02) 119 (0.02)
Tongue oedema 3 (0.02) 39 (0.15) 13 (0.03) 0 61 (0.07) 166 (0.05) 285 (0.06)
Tongue paralysis 2 (0.01) 4 (0.02) 4 (0.01) 0 9 (0.01) 30 (0.01) 52 (0.01)
Tongue pruritus 0 12 (0.05) 3 (0.01) 0 22 (0.03) 41 (0.01) 79 (0.02)
Tongue ulceration 0 2 (0.01) 7 (0.01) 0 6 (0.01) 47 (0.01) 62 (0.01)
Tonic clonic movements 0 8 (0.03) 2 (0.00) 0 20 (0.02) 63 (0.02) 94 (0.02)
Tonic convulsion 2 (0.01) 17 (0.07) 4 (0.01) 0 38 (0.04) 64 (0.02) 131 (0.03)
Tonsillar hypertrophy 0 7 (0.03) 13 (0.03) 0 8 (0.01) 108 (0.03) 137 (0.03)
Tonsillitis 1 (0.01) 5 (0.02) 21 (0.04) 0 21 (0.02) 155 (0.05) 205 (0.04)
Toothache 3 (0.02) 14 (0.06) 67 (0.14) 0 35 (0.04) 375 (0.11) 498 (0.10)
Toxic skin eruption 1 (0.01) 0 1 (0.00) 0 12 (0.01) 78 (0.02) 93 (0.02)
Transaminases increased 2 (0.01) 8 (0.03) 7 (0.01) 0 39 (0.05) 30 (0.01) 90 (0.02)
Transient global amnesia 0 0 8 (0.02) 0 77 (0.09) 34 (0.01) 119 (0.02)
Transient ischaemic attack 24 (0.13) 283 (1.12) 101 (0.21) 0 984 (1.15) 757 (0.23) 2197 (0.43)
Transverse sinus thrombosis 9 (0.05) 22 (0.09) 5 (0.01) 0 52 (0.06) 16 (0.00) 107 (0.02)
Tremor 52 (0.29) 341 (1.35) 1591 (3.25) 1 (0.22) 1199 (1.40) 9067 (2.70) 12338 (2.40)
Tricuspid valve incompetence 2 (0.01) 10 (0.04) 5 (0.01) 1 (0.22) 24 (0.03) 13 (0.00) 60 (0.01)
Trigeminal neuralgia 0 3 (0.01) 76 (0.16) 0 62 (0.07) 218 (0.06) 360 (0.07)
Trigger finger 0 0 18 (0.04) 0 2 (0.00) 40 (0.01) 60 (0.01)
Trismus 1 (0.01) 5 (0.02) 13 (0.03) 0 26 (0.03) 85 (0.03) 132 (0.03)
Troponin I increased 2 (0.01) 11 (0.04) 0 1 (0.22) 43 (0.05) 8 (0.00) 69 (0.01)
Troponin T increased 4 (0.02) 5 (0.02) 0 0 49 (0.06) 4 (0.00) 69 (0.01)
Troponin increased 17 (0.09) 64 (0.25) 8 (0.02) 0 306 (0.36) 50 (0.01) 497 (0.10)
Tunnel vision 0 3 (0.01) 12 (0.02) 0 7 (0.01) 182 (0.05) 206 (0.04)
Type 1 diabetes mellitus 2 (0.01) 28 (0.11) 13 (0.03) 0 39 (0.05) 49 (0.01) 135 (0.03)
Type 2 diabetes mellitus 12 (0.07) 6 (0.02) 6 (0.01) 0 27 (0.03) 25 (0.01) 85 (0.02)
Type I hypersensitivity 0 6 (0.02) 0 0 13 (0.02) 125 (0.04) 150 (0.03)
Ulcer 1 (0.01) 5 (0.02) 9 (0.02) 0 11 (0.01) 49 (0.01) 76 (0.01)
Ultrasound Doppler 1 (0.01) 20 (0.08) 7 (0.01) 0 30 (0.03) 61 (0.02) 120 (0.02)
Ultrasound Doppler abnormal 5 (0.03) 87 (0.34) 11 (0.02) 0 50 (0.06) 51 (0.02) 204 (0.04)
Ultrasound scan 0 28 (0.11) 6 (0.01) 0 28 (0.03) 88 (0.03) 150 (0.03)
Ultrasound scan abnormal 2 (0.01) 16 (0.06) 4 (0.01) 0 13 (0.02) 74 (0.02) 109 (0.02)
Unevaluable event 5 (0.03) 14 (0.06) 9 (0.02) 1 (0.22) 447 (0.52) 6 (0.00) 483 (0.09)
Unresponsive to stimuli 254 (1.39) 120 (0.47) 20 (0.04) 0 193 (0.22) 695 (0.21) 1405 (0.27)
Upper gastrointestinal haemorrhage 12 (0.07) 7 (0.03) 3 (0.01) 0 11 (0.01) 21 (0.01) 58 (0.01)
Upper respiratory tract infection 5 (0.03) 7 (0.03) 9 (0.02) 0 16 (0.02) 28 (0.01) 68 (0.01)
Urinary incontinence 10 (0.05) 45 (0.18) 68 (0.14) 0 115 (0.13) 178 (0.05) 442 (0.09)
Urinary retention 10 (0.05) 29 (0.11) 53 (0.11) 0 131 (0.15) 174 (0.05) 418 (0.08)
Urinary tract infection 78 (0.43) 61 (0.24) 82 (0.17) 0 350 (0.41) 439 (0.13) 1078 (0.21)
Urine output decreased 6 (0.03) 5 (0.02) 4 (0.01) 0 12 (0.01) 26 (0.01) 57 (0.01)
Urosepsis 25 (0.14) 12 (0.05) 0 0 31 (0.04) 5 (0.00) 77 (0.01)
Urticaria 6 (0.03) 317 (1.25) 349 (0.71) 1 (0.22) 963 (1.12) 4165 (1.24) 5863 (1.14)
Urticaria chronic 0 8 (0.03) 15 (0.03) 0 8 (0.01) 64 (0.02) 96 (0.02)
Uterine haemorrhage 0 6 (0.02) 7 (0.01) 1 (0.22) 20 (0.02) 128 (0.04) 165 (0.03)
Uterine pain 0 1 (0.00) 13 (0.03) 0 7 (0.01) 38 (0.01) 60 (0.01)
Uterine spasm 0 1 (0.00) 8 (0.02) 0 6 (0.01) 44 (0.01) 59 (0.01)
Uveitis 0 1 (0.00) 43 (0.09) 0 23 (0.03) 184 (0.05) 256 (0.05)
VIth nerve paralysis 0 2 (0.01) 26 (0.05) 0 38 (0.04) 59 (0.02) 127 (0.02)
Vaccination complication 34 (0.19) 46 (0.18) 61 (0.12) 0 153 (0.18) 205 (0.06) 517 (0.10)
Vaccination failure 630 (3.45) 177 (0.70) 14 (0.03) 0 1447 (1.69) 16849 (5.01) 19313 (3.75)
Vaccination site bruising 1 (0.01) 2 (0.01) 36 (0.07) 0 13 (0.02) 224 (0.07) 278 (0.05)
Vaccination site cellulitis 0 1 (0.00) 5 (0.01) 0 10 (0.01) 114 (0.03) 131 (0.03)
Vaccination site discolouration 1 (0.01) 2 (0.01) 9 (0.02) 0 8 (0.01) 35 (0.01) 56 (0.01)
Vaccination site discomfort 0 2 (0.01) 13 (0.03) 0 10 (0.01) 95 (0.03) 121 (0.02)
Vaccination site erythema 5 (0.03) 25 (0.10) 251 (0.51) 0 140 (0.16) 1361 (0.40) 1789 (0.35)
Vaccination site haematoma 2 (0.01) 1 (0.00) 22 (0.05) 0 13 (0.02) 66 (0.02) 104 (0.02)
Vaccination site haemorrhage 1 (0.01) 2 (0.01) 5 (0.01) 0 11 (0.01) 75 (0.02) 97 (0.02)
Vaccination site hypoaesthesia 0 5 (0.02) 17 (0.03) 0 10 (0.01) 81 (0.02) 113 (0.02)
Vaccination site induration 0 1 (0.00) 37 (0.08) 0 19 (0.02) 163 (0.05) 221 (0.04)
Vaccination site infection 0 1 (0.00) 8 (0.02) 0 5 (0.01) 47 (0.01) 61 (0.01)
Vaccination site inflammation 1 (0.01) 2 (0.01) 29 (0.06) 0 16 (0.02) 233 (0.07) 281 (0.05)
Vaccination site joint movement impairment 0 0 31 (0.06) 0 3 (0.00) 52 (0.02) 86 (0.02)
Vaccination site joint pain 0 1 (0.00) 32 (0.07) 0 5 (0.01) 51 (0.02) 89 (0.02)
Vaccination site lymphadenopathy 0 0 4 (0.01) 1 (0.22) 10 (0.01) 114 (0.03) 129 (0.03)
Vaccination site mass 0 9 (0.04) 78 (0.16) 0 20 (0.02) 630 (0.19) 742 (0.14)
Vaccination site movement impairment 0 6 (0.02) 173 (0.35) 0 47 (0.05) 233 (0.07) 462 (0.09)
Vaccination site oedema 0 4 (0.02) 101 (0.21) 0 34 (0.04) 216 (0.06) 357 (0.07)
Vaccination site pain 42 (0.23) 133 (0.52) 1416 (2.90) 0 610 (0.71) 6080 (1.81) 8339 (1.62)
Vaccination site paraesthesia 0 5 (0.02) 17 (0.03) 0 7 (0.01) 81 (0.02) 111 (0.02)
Vaccination site pruritus 0 14 (0.06) 109 (0.22) 0 60 (0.07) 517 (0.15) 704 (0.14)
Vaccination site rash 2 (0.01) 5 (0.02) 28 (0.06) 0 34 (0.04) 370 (0.11) 440 (0.09)
Vaccination site reaction 3 (0.02) 9 (0.04) 71 (0.15) 0 86 (0.10) 325 (0.10) 497 (0.10)
Vaccination site swelling 4 (0.02) 20 (0.08) 242 (0.50) 1 (0.22) 152 (0.18) 1268 (0.38) 1698 (0.33)
Vaccination site urticaria 0 5 (0.02) 5 (0.01) 0 19 (0.02) 74 (0.02) 106 (0.02)
Vaccination site warmth 0 4 (0.02) 107 (0.22) 0 44 (0.05) 701 (0.21) 857 (0.17)
Vaccine breakthrough infection 30 (0.16) 4 (0.02) 1 (0.00) 0 158 (0.18) 103 (0.03) 317 (0.06)
Vaginal discharge 1 (0.01) 2 (0.01) 6 (0.01) 2 (0.43) 13 (0.02) 91 (0.03) 115 (0.02)
Vaginal haemorrhage 1 (0.01) 51 (0.20) 103 (0.21) 15 (3.26) 170 (0.20) 1477 (0.44) 1823 (0.35)
Varicella 0 3 (0.01) 7 (0.01) 0 7 (0.01) 40 (0.01) 58 (0.01)
Varicose vein 0 17 (0.07) 26 (0.05) 0 18 (0.02) 157 (0.05) 220 (0.04)
Vascular headache 0 4 (0.02) 21 (0.04) 0 4 (0.00) 54 (0.02) 84 (0.02)
Vascular pain 1 (0.01) 13 (0.05) 27 (0.06) 0 21 (0.02) 145 (0.04) 211 (0.04)
Vascular purpura 1 (0.01) 0 0 0 27 (0.03) 27 (0.01) 55 (0.01)
Vasculitis 20 (0.11) 49 (0.19) 34 (0.07) 0 162 (0.19) 208 (0.06) 493 (0.10)
Vasodilatation 1 (0.01) 9 (0.04) 34 (0.07) 1 (0.22) 22 (0.03) 128 (0.04) 199 (0.04)
Vein disorder 0 5 (0.02) 10 (0.02) 0 11 (0.01) 48 (0.01) 75 (0.01)
Vena cava thrombosis 7 (0.04) 19 (0.07) 1 (0.00) 1 (0.22) 20 (0.02) 7 (0.00) 60 (0.01)
Venous occlusion 2 (0.01) 5 (0.02) 7 (0.01) 0 29 (0.03) 18 (0.01) 63 (0.01)
Venous thrombosis 12 (0.07) 98 (0.39) 26 (0.05) 0 154 (0.18) 239 (0.07) 544 (0.11)
Venous thrombosis limb 5 (0.03) 82 (0.32) 19 (0.04) 0 179 (0.21) 347 (0.10) 641 (0.12)
Ventricular extrasystoles 2 (0.01) 22 (0.09) 28 (0.06) 0 95 (0.11) 159 (0.05) 317 (0.06)
Ventricular fibrillation 89 (0.49) 82 (0.32) 2 (0.00) 0 37 (0.04) 9 (0.00) 246 (0.05)
Ventricular hypokinesia 1 (0.01) 14 (0.06) 3 (0.01) 0 41 (0.05) 9 (0.00) 77 (0.01)
Ventricular tachycardia 31 (0.17) 72 (0.28) 4 (0.01) 0 90 (0.10) 48 (0.01) 263 (0.05)
Vertebral artery dissection 2 (0.01) 15 (0.06) 2 (0.00) 0 25 (0.03) 10 (0.00) 54 (0.01)
Vertigo 12 (0.07) 176 (0.69) 1131 (2.31) 2 (0.43) 916 (1.07) 3313 (0.99) 5619 (1.09)
Vertigo positional 0 5 (0.02) 57 (0.12) 0 65 (0.08) 188 (0.06) 317 (0.06)
Vestibular disorder 0 2 (0.01) 32 (0.07) 0 29 (0.03) 33 (0.01) 97 (0.02)
Vestibular migraine 0 0 23 (0.05) 0 12 (0.01) 35 (0.01) 70 (0.01)
Vestibular neuronitis 0 5 (0.02) 53 (0.11) 1 (0.22) 175 (0.20) 148 (0.04) 385 (0.07)
Viral infection 5 (0.03) 13 (0.05) 35 (0.07) 0 68 (0.08) 97 (0.03) 223 (0.04)
Viral rash 0 0 1 (0.00) 0 4 (0.00) 71 (0.02) 76 (0.01)
Vision blurred 20 (0.11) 200 (0.79) 939 (1.92) 5 (1.09) 759 (0.88) 3197 (0.95) 5175 (1.01)
Visual acuity reduced 1 (0.01) 7 (0.03) 49 (0.10) 0 45 (0.05) 136 (0.04) 243 (0.05)
Visual field defect 1 (0.01) 15 (0.06) 74 (0.15) 0 97 (0.11) 112 (0.03) 313 (0.06)
Visual impairment 22 (0.12) 134 (0.53) 613 (1.25) 2 (0.43) 745 (0.87) 1265 (0.38) 2850 (0.55)
Vitreous detachment 0 0 32 (0.07) 0 12 (0.01) 155 (0.05) 201 (0.04)
Vitreous floaters 2 (0.01) 2 (0.01) 68 (0.14) 0 28 (0.03) 218 (0.06) 320 (0.06)
Vitreous haemorrhage 0 1 (0.00) 7 (0.01) 0 13 (0.02) 30 (0.01) 57 (0.01)
Vomiting 497 (2.73) 841 (3.32) 2439 (4.99) 3 (0.65) 3566 (4.15) 12939 (3.85) 20621 (4.01)
Vomiting projectile 3 (0.02) 3 (0.01) 40 (0.08) 0 16 (0.02) 154 (0.05) 216 (0.04)
Vulvovaginal candidiasis 0 0 8 (0.02) 0 3 (0.00) 47 (0.01) 58 (0.01)
Vulvovaginal pain 0 2 (0.01) 14 (0.03) 0 5 (0.01) 47 (0.01) 68 (0.01)
Walking aid user 6 (0.03) 13 (0.05) 38 (0.08) 0 26 (0.03) 8 (0.00) 94 (0.02)
Walking disability 1 (0.01) 4 (0.02) 27 (0.06) 0 18 (0.02) 20 (0.01) 75 (0.01)
Weight bearing difficulty 1 (0.01) 3 (0.01) 22 (0.05) 1 (0.22) 42 (0.05) 27 (0.01) 100 (0.02)
Weight decreased 23 (0.13) 59 (0.23) 201 (0.41) 0 259 (0.30) 413 (0.12) 1006 (0.20)
Weight increased 4 (0.02) 12 (0.05) 33 (0.07) 0 50 (0.06) 88 (0.03) 194 (0.04)
Wheezing 27 (0.15) 155 (0.61) 112 (0.23) 0 329 (0.38) 876 (0.26) 1544 (0.30)
White blood cell count decreased 0 15 (0.06) 10 (0.02) 0 57 (0.07) 63 (0.02) 157 (0.03)
White blood cell count increased 12 (0.07) 32 (0.13) 22 (0.05) 0 139 (0.16) 58 (0.02) 291 (0.06)
White matter lesion 0 10 (0.04) 15 (0.03) 0 35 (0.04) 5 (0.00) 70 (0.01)
Withdrawal syndrome 0 2 (0.01) 8 (0.02) 0 3 (0.00) 72 (0.02) 85 (0.02)
Wound 0 4 (0.02) 9 (0.02) 0 28 (0.03) 46 (0.01) 92 (0.02)
X-ray 2 (0.01) 22 (0.09) 11 (0.02) 0 13 (0.02) 13 (0.00) 61 (0.01)
Yawning 0 6 (0.02) 9 (0.02) 0 8 (0.01) 70 (0.02) 95 (0.02)
Yellow skin 0 13 (0.05) 6 (0.01) 0 8 (0.01) 28 (0.01) 57 (0.01)