Eudravigilance C-19 - Astrazeneca
Liste des effets indésirables (uniquement ceux qui apparaissent dans plus de 50 cas graves)
PT |
Décès 4877 (%) |
Mise en jeu du pronostic vital 9211 (%) |
Invalidité ou incapacité 24244 (%) |
Anomalies congénitales 157 (%) |
Hospitalisation 24779 (%) |
Médicalement significatif 160991 (%) |
Cas Graves 224259 (%) |
---|---|---|---|---|---|---|---|
Abdominal discomfort | 12 (0.25) | 18 (0.20) | 163 (0.67) | 0 | 59 (0.24) | 1075 (0.67) | 1335 (0.60) |
Abdominal distension | 11 (0.23) | 13 (0.14) | 96 (0.40) | 1 (0.64) | 39 (0.16) | 410 (0.25) | 574 (0.26) |
Abdominal pain | 99 (2.03) | 170 (1.85) | 616 (2.54) | 2 (1.27) | 494 (1.99) | 3079 (1.91) | 4520 (2.02) |
Abdominal pain lower | 0 | 7 (0.08) | 28 (0.12) | 0 | 53 (0.21) | 185 (0.11) | 275 (0.12) |
Abdominal pain upper | 24 (0.49) | 71 (0.77) | 562 (2.32) | 2 (1.27) | 249 (1.00) | 3668 (2.28) | 4595 (2.05) |
Abdominal rigidity | 2 (0.04) | 1 (0.01) | 11 (0.05) | 0 | 4 (0.02) | 39 (0.02) | 57 (0.03) |
Abnormal dreams | 1 (0.02) | 3 (0.03) | 29 (0.12) | 0 | 4 (0.02) | 237 (0.15) | 274 (0.12) |
Abnormal loss of weight | 2 (0.04) | 6 (0.07) | 25 (0.10) | 0 | 7 (0.03) | 40 (0.02) | 81 (0.04) |
Abortion spontaneous | 3 (0.06) | 14 (0.15) | 23 (0.09) | 69 (43.95) | 37 (0.15) | 171 (0.11) | 321 (0.14) |
Abscess | 0 | 1 (0.01) | 7 (0.03) | 0 | 15 (0.06) | 28 (0.02) | 54 (0.02) |
Acne | 1 (0.02) | 3 (0.03) | 8 (0.03) | 0 | 4 (0.02) | 81 (0.05) | 98 (0.04) |
Activated partial thromboplastin time prolonged | 3 (0.06) | 46 (0.50) | 6 (0.02) | 0 | 28 (0.11) | 46 (0.03) | 131 (0.06) |
Acute coronary syndrome | 29 (0.59) | 23 (0.25) | 0 | 0 | 61 (0.25) | 6 (0.00) | 120 (0.05) |
Acute disseminated encephalomyelitis | 3 (0.06) | 10 (0.11) | 8 (0.03) | 0 | 23 (0.09) | 8 (0.00) | 55 (0.02) |
Acute kidney injury | 26 (0.53) | 39 (0.42) | 11 (0.05) | 0 | 74 (0.30) | 29 (0.02) | 194 (0.09) |
Acute myocardial infarction | 109 (2.23) | 129 (1.40) | 3 (0.01) | 0 | 146 (0.59) | 25 (0.02) | 427 (0.19) |
Acute respiratory distress syndrome | 44 (0.90) | 13 (0.14) | 0 | 0 | 65 (0.26) | 59 (0.04) | 187 (0.08) |
Acute respiratory failure | 29 (0.59) | 10 (0.11) | 0 | 0 | 26 (0.10) | 1 (0.00) | 68 (0.03) |
Administration site pain | 0 | 20 (0.22) | 19 (0.08) | 1 (0.64) | 6 (0.02) | 29 (0.02) | 76 (0.03) |
Adverse drug reaction | 0 | 2 (0.02) | 18 (0.07) | 1 (0.64) | 5 (0.02) | 80 (0.05) | 107 (0.05) |
Adverse event following immunisation | 110 (2.26) | 0 | 1 (0.00) | 0 | 1 (0.00) | 0 | 112 (0.05) |
Ageusia | 15 (0.31) | 14 (0.15) | 160 (0.66) | 0 | 79 (0.32) | 671 (0.42) | 943 (0.42) |
Agitation | 14 (0.29) | 22 (0.24) | 35 (0.14) | 0 | 25 (0.10) | 123 (0.08) | 229 (0.10) |
Allergy to vaccine | 0 | 6 (0.07) | 5 (0.02) | 0 | 3 (0.01) | 40 (0.02) | 54 (0.02) |
Alopecia | 0 | 12 (0.13) | 56 (0.23) | 1 (0.64) | 12 (0.05) | 270 (0.17) | 353 (0.16) |
Altered state of consciousness | 15 (0.31) | 7 (0.08) | 5 (0.02) | 0 | 27 (0.11) | 21 (0.01) | 85 (0.04) |
Amenorrhoea | 0 | 9 (0.10) | 47 (0.19) | 2 (1.27) | 10 (0.04) | 271 (0.17) | 339 (0.15) |
Amnesia | 2 (0.04) | 52 (0.56) | 132 (0.54) | 0 | 93 (0.38) | 241 (0.15) | 527 (0.23) |
Anaemia | 12 (0.25) | 30 (0.33) | 35 (0.14) | 0 | 65 (0.26) | 107 (0.07) | 260 (0.12) |
Anal incontinence | 2 (0.04) | 6 (0.07) | 12 (0.05) | 0 | 14 (0.06) | 19 (0.01) | 55 (0.02) |
Anaphylactic reaction | 10 (0.21) | 357 (3.88) | 23 (0.09) | 0 | 263 (1.06) | 555 (0.34) | 1225 (0.55) |
Anaphylactic shock | 8 (0.16) | 66 (0.72) | 13 (0.05) | 0 | 61 (0.25) | 100 (0.06) | 255 (0.11) |
Anaphylactoid reaction | 0 | 6 (0.07) | 2 (0.01) | 0 | 7 (0.03) | 60 (0.04) | 75 (0.03) |
Anger | 1 (0.02) | 6 (0.07) | 10 (0.04) | 0 | 1 (0.00) | 51 (0.03) | 71 (0.03) |
Angina pectoris | 5 (0.10) | 48 (0.52) | 51 (0.21) | 1 (0.64) | 90 (0.36) | 177 (0.11) | 383 (0.17) |
Angioedema | 0 | 64 (0.69) | 28 (0.12) | 0 | 61 (0.25) | 486 (0.30) | 653 (0.29) |
Anosmia | 16 (0.33) | 8 (0.09) | 66 (0.27) | 0 | 54 (0.22) | 215 (0.13) | 365 (0.16) |
Anxiety | 3 (0.06) | 47 (0.51) | 245 (1.01) | 0 | 152 (0.61) | 836 (0.52) | 1292 (0.58) |
Aortic thrombosis | 11 (0.23) | 15 (0.16) | 1 (0.00) | 0 | 19 (0.08) | 5 (0.00) | 59 (0.03) |
Apathy | 0 | 1 (0.01) | 25 (0.10) | 0 | 11 (0.04) | 47 (0.03) | 86 (0.04) |
Aphasia | 26 (0.53) | 67 (0.73) | 56 (0.23) | 0 | 107 (0.43) | 172 (0.11) | 472 (0.21) |
Aphonia | 1 (0.02) | 8 (0.09) | 18 (0.07) | 0 | 11 (0.04) | 73 (0.05) | 113 (0.05) |
Aphthous ulcer | 1 (0.02) | 1 (0.01) | 5 (0.02) | 0 | 5 (0.02) | 49 (0.03) | 62 (0.03) |
Appendicitis | 2 (0.04) | 16 (0.17) | 4 (0.02) | 0 | 42 (0.17) | 20 (0.01) | 84 (0.04) |
Application site pain | 3 (0.06) | 7 (0.08) | 5 (0.02) | 0 | 11 (0.04) | 70 (0.04) | 99 (0.04) |
Areflexia | 1 (0.02) | 11 (0.12) | 16 (0.07) | 0 | 23 (0.09) | 1 (0.00) | 57 (0.03) |
Arrhythmia | 11 (0.23) | 36 (0.39) | 43 (0.18) | 0 | 200 (0.81) | 365 (0.23) | 670 (0.30) |
Arterial thrombosis | 11 (0.23) | 33 (0.36) | 7 (0.03) | 0 | 26 (0.10) | 24 (0.01) | 108 (0.05) |
Arthralgia | 40 (0.82) | 195 (2.12) | 4247 (17.52) | 3 (1.91) | 643 (2.59) | 16442 (10.21) | 21629 (9.64) |
Arthritis | 0 | 6 (0.07) | 167 (0.69) | 0 | 34 (0.14) | 370 (0.23) | 582 (0.26) |
Arthritis reactive | 0 | 1 (0.01) | 27 (0.11) | 0 | 9 (0.04) | 32 (0.02) | 69 (0.03) |
Asthenia | 127 (2.60) | 198 (2.15) | 1091 (4.50) | 1 (0.64) | 830 (3.35) | 3983 (2.47) | 6318 (2.82) |
Asthenopia | 0 | 3 (0.03) | 46 (0.19) | 0 | 10 (0.04) | 220 (0.14) | 280 (0.12) |
Asthma | 3 (0.06) | 38 (0.41) | 105 (0.43) | 0 | 53 (0.21) | 428 (0.27) | 630 (0.28) |
Ataxia | 2 (0.04) | 12 (0.13) | 22 (0.09) | 0 | 48 (0.19) | 19 (0.01) | 111 (0.05) |
Atrial fibrillation | 19 (0.39) | 94 (1.02) | 41 (0.17) | 0 | 217 (0.88) | 266 (0.17) | 659 (0.29) |
Atrial flutter | 0 | 6 (0.07) | 8 (0.03) | 0 | 21 (0.08) | 26 (0.02) | 64 (0.03) |
Autoimmune disorder | 2 (0.04) | 12 (0.13) | 27 (0.11) | 0 | 21 (0.08) | 47 (0.03) | 113 (0.05) |
Axillary mass | 0 | 1 (0.01) | 8 (0.03) | 0 | 3 (0.01) | 40 (0.02) | 53 (0.02) |
Axillary pain | 0 | 1 (0.01) | 60 (0.25) | 0 | 15 (0.06) | 463 (0.29) | 541 (0.24) |
Back pain | 34 (0.70) | 103 (1.12) | 808 (3.33) | 2 (1.27) | 331 (1.34) | 3939 (2.45) | 5238 (2.34) |
Balance disorder | 7 (0.14) | 55 (0.60) | 292 (1.20) | 0 | 143 (0.58) | 592 (0.37) | 1108 (0.49) |
Bedridden | 3 (0.06) | 5 (0.05) | 55 (0.23) | 0 | 9 (0.04) | 95 (0.06) | 173 (0.08) |
Bell's palsy | 1 (0.02) | 18 (0.20) | 142 (0.59) | 0 | 146 (0.59) | 395 (0.25) | 707 (0.32) |
Bladder pain | 0 | 1 (0.01) | 9 (0.04) | 0 | 5 (0.02) | 43 (0.03) | 59 (0.03) |
Blepharospasm | 0 | 1 (0.01) | 22 (0.09) | 0 | 6 (0.02) | 58 (0.04) | 87 (0.04) |
Blindness | 2 (0.04) | 35 (0.38) | 140 (0.58) | 0 | 56 (0.23) | 215 (0.13) | 467 (0.21) |
Blindness transient | 0 | 4 (0.04) | 9 (0.04) | 0 | 10 (0.04) | 47 (0.03) | 74 (0.03) |
Blindness unilateral | 1 (0.02) | 10 (0.11) | 44 (0.18) | 0 | 17 (0.07) | 40 (0.02) | 115 (0.05) |
Blister | 1 (0.02) | 16 (0.17) | 52 (0.21) | 0 | 27 (0.11) | 339 (0.21) | 442 (0.20) |
Blood blister | 0 | 2 (0.02) | 10 (0.04) | 0 | 6 (0.02) | 53 (0.03) | 73 (0.03) |
Blood fibrinogen increased | 2 (0.04) | 6 (0.07) | 2 (0.01) | 0 | 14 (0.06) | 17 (0.01) | 52 (0.02) |
Blood glucose increased | 1 (0.02) | 7 (0.08) | 17 (0.07) | 0 | 17 (0.07) | 130 (0.08) | 178 (0.08) |
Blood pressure decreased | 7 (0.14) | 25 (0.27) | 38 (0.16) | 0 | 54 (0.22) | 110 (0.07) | 239 (0.11) |
Blood pressure fluctuation | 1 (0.02) | 16 (0.17) | 16 (0.07) | 0 | 20 (0.08) | 40 (0.02) | 101 (0.05) |
Blood pressure increased | 10 (0.21) | 85 (0.92) | 95 (0.39) | 0 | 216 (0.87) | 355 (0.22) | 775 (0.35) |
Blood pressure measurement | 0 | 10 (0.11) | 12 (0.05) | 0 | 17 (0.07) | 65 (0.04) | 104 (0.05) |
Blood test abnormal | 0 | 5 (0.05) | 24 (0.10) | 0 | 29 (0.12) | 40 (0.02) | 99 (0.04) |
Blood urine present | 1 (0.02) | 7 (0.08) | 5 (0.02) | 0 | 9 (0.04) | 63 (0.04) | 89 (0.04) |
Body temperature | 0 | 1 (0.01) | 72 (0.30) | 0 | 11 (0.04) | 676 (0.42) | 763 (0.34) |
Body temperature abnormal | 0 | 1 (0.01) | 9 (0.04) | 0 | 3 (0.01) | 52 (0.03) | 65 (0.03) |
Body temperature decreased | 1 (0.02) | 3 (0.03) | 17 (0.07) | 0 | 5 (0.02) | 101 (0.06) | 128 (0.06) |
Body temperature fluctuation | 0 | 3 (0.03) | 29 (0.12) | 0 | 1 (0.00) | 127 (0.08) | 160 (0.07) |
Body temperature increased | 5 (0.10) | 14 (0.15) | 99 (0.41) | 1 (0.64) | 86 (0.35) | 821 (0.51) | 1028 (0.46) |
Bone pain | 2 (0.04) | 28 (0.30) | 231 (0.95) | 0 | 32 (0.13) | 782 (0.49) | 1078 (0.48) |
Bradycardia | 12 (0.25) | 21 (0.23) | 17 (0.07) | 0 | 38 (0.15) | 55 (0.03) | 158 (0.07) |
Bradyphrenia | 0 | 2 (0.02) | 19 (0.08) | 0 | 6 (0.02) | 64 (0.04) | 91 (0.04) |
Brain injury | 16 (0.33) | 18 (0.20) | 5 (0.02) | 0 | 6 (0.02) | 9 (0.01) | 64 (0.03) |
Brain oedema | 39 (0.80) | 15 (0.16) | 3 (0.01) | 0 | 13 (0.05) | 14 (0.01) | 88 (0.04) |
Breast cancer | 0 | 7 (0.08) | 5 (0.02) | 0 | 6 (0.02) | 33 (0.02) | 52 (0.02) |
Breast mass | 0 | 2 (0.02) | 6 (0.02) | 0 | 7 (0.03) | 40 (0.02) | 56 (0.02) |
Breast pain | 0 | 0 | 44 (0.18) | 1 (0.64) | 30 (0.12) | 277 (0.17) | 353 (0.16) |
Breast swelling | 0 | 0 | 8 (0.03) | 0 | 4 (0.02) | 40 (0.02) | 52 (0.02) |
Bronchospasm | 0 | 7 (0.08) | 3 (0.01) | 0 | 16 (0.06) | 26 (0.02) | 53 (0.02) |
Burning sensation | 0 | 31 (0.34) | 168 (0.69) | 2 (1.27) | 70 (0.28) | 626 (0.39) | 904 (0.40) |
Bursitis | 0 | 2 (0.02) | 80 (0.33) | 0 | 9 (0.04) | 122 (0.08) | 213 (0.09) |
C-reactive protein increased | 7 (0.14) | 11 (0.12) | 17 (0.07) | 0 | 64 (0.26) | 44 (0.03) | 156 (0.07) |
COVID-19 | 278 (5.70) | 163 (1.77) | 215 (0.89) | 2 (1.27) | 689 (2.78) | 10453 (6.49) | 11824 (5.27) |
COVID-19 immunisation | 4 (0.08) | 12 (0.13) | 62 (0.26) | 0 | 34 (0.14) | 138 (0.09) | 251 (0.11) |
COVID-19 pneumonia | 66 (1.35) | 32 (0.35) | 13 (0.05) | 0 | 168 (0.68) | 26 (0.02) | 305 (0.14) |
Candida infection | 1 (0.02) | 1 (0.01) | 6 (0.02) | 0 | 2 (0.01) | 46 (0.03) | 56 (0.02) |
Cardiac arrest | 247 (5.06) | 92 (1.00) | 4 (0.02) | 0 | 15 (0.06) | 41 (0.03) | 419 (0.19) |
Cardiac disorder | 4 (0.08) | 27 (0.29) | 10 (0.04) | 0 | 46 (0.19) | 41 (0.03) | 136 (0.06) |
Cardiac failure | 63 (1.29) | 61 (0.66) | 21 (0.09) | 0 | 76 (0.31) | 26 (0.02) | 259 (0.12) |
Cardiac flutter | 0 | 8 (0.09) | 30 (0.12) | 0 | 14 (0.06) | 169 (0.10) | 222 (0.10) |
Cardio-respiratory arrest | 68 (1.39) | 18 (0.20) | 0 | 0 | 5 (0.02) | 4 (0.00) | 98 (0.04) |
Cardiovascular disorder | 16 (0.33) | 8 (0.09) | 49 (0.20) | 0 | 45 (0.18) | 32 (0.02) | 154 (0.07) |
Cellulitis | 3 (0.06) | 13 (0.14) | 39 (0.16) | 0 | 56 (0.23) | 287 (0.18) | 402 (0.18) |
Cerebral artery thrombosis | 11 (0.23) | 17 (0.18) | 3 (0.01) | 0 | 10 (0.04) | 8 (0.00) | 52 (0.02) |
Cerebral haemorrhage | 197 (4.04) | 146 (1.59) | 27 (0.11) | 0 | 116 (0.47) | 47 (0.03) | 559 (0.25) |
Cerebral infarction | 42 (0.86) | 110 (1.19) | 34 (0.14) | 0 | 176 (0.71) | 53 (0.03) | 432 (0.19) |
Cerebral ischaemia | 7 (0.14) | 13 (0.14) | 5 (0.02) | 0 | 27 (0.11) | 10 (0.01) | 67 (0.03) |
Cerebral thrombosis | 54 (1.11) | 38 (0.41) | 4 (0.02) | 0 | 70 (0.28) | 41 (0.03) | 221 (0.10) |
Cerebral venous sinus thrombosis | 103 (2.11) | 234 (2.54) | 20 (0.08) | 0 | 252 (1.02) | 75 (0.05) | 704 (0.31) |
Cerebral venous thrombosis | 44 (0.90) | 53 (0.58) | 5 (0.02) | 0 | 81 (0.33) | 36 (0.02) | 229 (0.10) |
Cerebrovascular accident | 191 (3.92) | 539 (5.85) | 252 (1.04) | 3 (1.91) | 767 (3.10) | 581 (0.36) | 2399 (1.07) |
Chest discomfort | 16 (0.33) | 91 (0.99) | 297 (1.23) | 0 | 326 (1.32) | 1393 (0.87) | 2155 (0.96) |
Chest pain | 107 (2.19) | 487 (5.29) | 871 (3.59) | 1 (0.64) | 1119 (4.52) | 3538 (2.20) | 6226 (2.78) |
Chills | 65 (1.33) | 380 (4.13) | 5692 (23.48) | 7 (4.46) | 1285 (5.19) | 31777 (19.74) | 39264 (17.51) |
Chromaturia | 3 (0.06) | 5 (0.05) | 13 (0.05) | 0 | 7 (0.03) | 75 (0.05) | 105 (0.05) |
Chronic fatigue syndrome | 0 | 1 (0.01) | 85 (0.35) | 0 | 9 (0.04) | 64 (0.04) | 160 (0.07) |
Chronic obstructive pulmonary disease | 20 (0.41) | 10 (0.11) | 6 (0.02) | 0 | 19 (0.08) | 23 (0.01) | 79 (0.04) |
Circulatory collapse | 62 (1.27) | 47 (0.51) | 15 (0.06) | 0 | 77 (0.31) | 123 (0.08) | 348 (0.16) |
Clumsiness | 0 | 1 (0.01) | 19 (0.08) | 0 | 6 (0.02) | 27 (0.02) | 54 (0.02) |
Cluster headache | 2 (0.04) | 12 (0.13) | 96 (0.40) | 0 | 24 (0.10) | 494 (0.31) | 629 (0.28) |
Coagulopathy | 21 (0.43) | 43 (0.47) | 34 (0.14) | 1 (0.64) | 52 (0.21) | 72 (0.04) | 231 (0.10) |
Cognitive disorder | 3 (0.06) | 9 (0.10) | 98 (0.40) | 0 | 23 (0.09) | 106 (0.07) | 250 (0.11) |
Cold sweat | 12 (0.25) | 32 (0.35) | 181 (0.75) | 1 (0.64) | 69 (0.28) | 1148 (0.71) | 1452 (0.65) |
Cold-stimulus headache | 0 | 3 (0.03) | 15 (0.06) | 0 | 3 (0.01) | 54 (0.03) | 75 (0.03) |
Colitis | 1 (0.02) | 3 (0.03) | 7 (0.03) | 0 | 27 (0.11) | 41 (0.03) | 79 (0.04) |
Colitis ulcerative | 0 | 3 (0.03) | 20 (0.08) | 0 | 17 (0.07) | 73 (0.05) | 113 (0.05) |
Coma | 27 (0.55) | 31 (0.34) | 3 (0.01) | 0 | 12 (0.05) | 3 (0.00) | 98 (0.04) |
Condition aggravated | 15 (0.31) | 20 (0.22) | 148 (0.61) | 0 | 66 (0.27) | 302 (0.19) | 558 (0.25) |
Confusional state | 52 (1.07) | 149 (1.62) | 429 (1.77) | 1 (0.64) | 284 (1.15) | 1320 (0.82) | 2274 (1.01) |
Conjunctival haemorrhage | 0 | 4 (0.04) | 8 (0.03) | 0 | 7 (0.03) | 86 (0.05) | 106 (0.05) |
Conjunctivitis | 1 (0.02) | 0 | 7 (0.03) | 0 | 7 (0.03) | 53 (0.03) | 68 (0.03) |
Constipation | 3 (0.06) | 15 (0.16) | 91 (0.38) | 0 | 36 (0.15) | 272 (0.17) | 420 (0.19) |
Contusion | 17 (0.35) | 83 (0.90) | 225 (0.93) | 0 | 180 (0.73) | 1597 (0.99) | 2128 (0.95) |
Coordination abnormal | 5 (0.10) | 6 (0.07) | 32 (0.13) | 0 | 21 (0.08) | 82 (0.05) | 152 (0.07) |
Coronary artery thrombosis | 18 (0.37) | 24 (0.26) | 0 | 0 | 11 (0.04) | 9 (0.01) | 66 (0.03) |
Costochondritis | 0 | 1 (0.01) | 21 (0.09) | 0 | 10 (0.04) | 54 (0.03) | 86 (0.04) |
Cough | 237 (4.86) | 143 (1.55) | 489 (2.02) | 2 (1.27) | 649 (2.62) | 2537 (1.58) | 4105 (1.83) |
Crohn's disease | 0 | 1 (0.01) | 25 (0.10) | 0 | 12 (0.05) | 56 (0.03) | 94 (0.04) |
Crying | 1 (0.02) | 7 (0.08) | 48 (0.20) | 0 | 11 (0.04) | 199 (0.12) | 266 (0.12) |
Cutaneous vasculitis | 0 | 0 | 2 (0.01) | 0 | 24 (0.10) | 51 (0.03) | 79 (0.04) |
Cyanosis | 25 (0.51) | 18 (0.20) | 18 (0.07) | 0 | 94 (0.38) | 88 (0.05) | 251 (0.11) |
Cystitis | 1 (0.02) | 1 (0.01) | 11 (0.05) | 0 | 12 (0.05) | 81 (0.05) | 106 (0.05) |
Deafness | 1 (0.02) | 9 (0.10) | 158 (0.65) | 0 | 32 (0.13) | 289 (0.18) | 491 (0.22) |
Deafness neurosensory | 1 (0.02) | 1 (0.01) | 34 (0.14) | 0 | 1 (0.00) | 20 (0.01) | 60 (0.03) |
Deafness unilateral | 0 | 2 (0.02) | 41 (0.17) | 0 | 8 (0.03) | 58 (0.04) | 110 (0.05) |
Death | 746 (15.30) | 1 (0.01) | 0 | 0 | 0 | 2 (0.00) | 752 (0.34) |
Decreased appetite | 76 (1.56) | 78 (0.85) | 850 (3.51) | 2 (1.27) | 278 (1.12) | 4740 (2.94) | 6061 (2.70) |
Deep vein thrombosis | 79 (1.62) | 546 (5.93) | 115 (0.47) | 0 | 1120 (4.52) | 1955 (1.21) | 3939 (1.76) |
Dehydration | 6 (0.12) | 18 (0.20) | 75 (0.31) | 0 | 88 (0.36) | 416 (0.26) | 610 (0.27) |
Delirium | 9 (0.18) | 16 (0.17) | 81 (0.33) | 0 | 47 (0.19) | 326 (0.20) | 487 (0.22) |
Delusion | 1 (0.02) | 2 (0.02) | 14 (0.06) | 0 | 8 (0.03) | 35 (0.02) | 63 (0.03) |
Demyelination | 1 (0.02) | 5 (0.05) | 17 (0.07) | 0 | 16 (0.06) | 21 (0.01) | 62 (0.03) |
Depressed level of consciousness | 29 (0.59) | 19 (0.21) | 13 (0.05) | 0 | 50 (0.20) | 60 (0.04) | 184 (0.08) |
Depressed mood | 1 (0.02) | 9 (0.10) | 106 (0.44) | 0 | 11 (0.04) | 471 (0.29) | 599 (0.27) |
Depression | 4 (0.08) | 31 (0.34) | 146 (0.60) | 0 | 25 (0.10) | 434 (0.27) | 645 (0.29) |
Dermatitis | 0 | 5 (0.05) | 13 (0.05) | 0 | 8 (0.03) | 107 (0.07) | 134 (0.06) |
Dermatitis allergic | 0 | 10 (0.11) | 18 (0.07) | 0 | 11 (0.04) | 182 (0.11) | 223 (0.10) |
Dermatitis bullous | 1 (0.02) | 4 (0.04) | 5 (0.02) | 0 | 4 (0.02) | 46 (0.03) | 60 (0.03) |
Diabetes mellitus | 7 (0.14) | 15 (0.16) | 19 (0.08) | 0 | 25 (0.10) | 79 (0.05) | 147 (0.07) |
Diabetic ketoacidosis | 5 (0.10) | 14 (0.15) | 1 (0.00) | 0 | 17 (0.07) | 13 (0.01) | 54 (0.02) |
Diarrhoea | 97 (1.99) | 137 (1.49) | 1009 (4.16) | 0 | 529 (2.13) | 6138 (3.81) | 7952 (3.55) |
Diplegia | 5 (0.10) | 8 (0.09) | 25 (0.10) | 0 | 17 (0.07) | 41 (0.03) | 100 (0.04) |
Diplopia | 1 (0.02) | 26 (0.28) | 105 (0.43) | 0 | 112 (0.45) | 219 (0.14) | 469 (0.21) |
Discomfort | 5 (0.10) | 15 (0.16) | 89 (0.37) | 1 (0.64) | 52 (0.21) | 380 (0.24) | 550 (0.25) |
Disorientation | 13 (0.27) | 19 (0.21) | 113 (0.47) | 0 | 91 (0.37) | 507 (0.31) | 756 (0.34) |
Disseminated intravascular coagulation | 30 (0.62) | 26 (0.28) | 1 (0.00) | 0 | 15 (0.06) | 2 (0.00) | 78 (0.03) |
Dissociation | 0 | 2 (0.02) | 11 (0.05) | 0 | 3 (0.01) | 45 (0.03) | 61 (0.03) |
Disturbance in attention | 1 (0.02) | 26 (0.28) | 218 (0.90) | 0 | 112 (0.45) | 517 (0.32) | 884 (0.39) |
Diverticulitis | 3 (0.06) | 4 (0.04) | 6 (0.02) | 0 | 23 (0.09) | 25 (0.02) | 61 (0.03) |
Dizziness | 71 (1.46) | 430 (4.67) | 2780 (11.47) | 5 (3.18) | 1613 (6.51) | 15413 (9.57) | 20419 (9.11) |
Dizziness exertional | 0 | 1 (0.01) | 17 (0.07) | 0 | 1 (0.00) | 76 (0.05) | 95 (0.04) |
Dizziness postural | 2 (0.04) | 7 (0.08) | 228 (0.94) | 0 | 55 (0.22) | 1481 (0.92) | 1775 (0.79) |
Drug hypersensitivity | 0 | 8 (0.09) | 5 (0.02) | 0 | 6 (0.02) | 38 (0.02) | 57 (0.03) |
Drug ineffective | 16 (0.33) | 14 (0.15) | 21 (0.09) | 0 | 54 (0.22) | 167 (0.10) | 276 (0.12) |
Dry eye | 0 | 3 (0.03) | 42 (0.17) | 0 | 16 (0.06) | 192 (0.12) | 253 (0.11) |
Dry mouth | 1 (0.02) | 11 (0.12) | 118 (0.49) | 0 | 44 (0.18) | 729 (0.45) | 906 (0.40) |
Dry skin | 0 | 2 (0.02) | 38 (0.16) | 0 | 13 (0.05) | 230 (0.14) | 283 (0.13) |
Dry throat | 1 (0.02) | 4 (0.04) | 24 (0.10) | 0 | 7 (0.03) | 153 (0.10) | 189 (0.08) |
Dysaesthesia | 0 | 3 (0.03) | 7 (0.03) | 0 | 24 (0.10) | 44 (0.03) | 82 (0.04) |
Dysarthria | 28 (0.57) | 69 (0.75) | 100 (0.41) | 0 | 172 (0.69) | 234 (0.15) | 623 (0.28) |
Dysgeusia | 3 (0.06) | 13 (0.14) | 153 (0.63) | 1 (0.64) | 30 (0.12) | 1046 (0.65) | 1254 (0.56) |
Dyskinesia | 4 (0.08) | 4 (0.04) | 29 (0.12) | 0 | 19 (0.08) | 78 (0.05) | 141 (0.06) |
Dysmenorrhoea | 0 | 2 (0.02) | 115 (0.47) | 1 (0.64) | 25 (0.10) | 882 (0.55) | 1028 (0.46) |
Dyspepsia | 4 (0.08) | 21 (0.23) | 94 (0.39) | 0 | 33 (0.13) | 551 (0.34) | 707 (0.32) |
Dysphagia | 17 (0.35) | 42 (0.46) | 50 (0.21) | 1 (0.64) | 78 (0.31) | 174 (0.11) | 381 (0.17) |
Dysphonia | 1 (0.02) | 20 (0.22) | 42 (0.17) | 0 | 31 (0.13) | 106 (0.07) | 202 (0.09) |
Dyspnoea | 515 (10.56) | 911 (9.89) | 1284 (5.30) | 1 (0.64) | 2202 (8.89) | 4905 (3.05) | 10057 (4.48) |
Dyspnoea exertional | 8 (0.16) | 22 (0.24) | 31 (0.13) | 0 | 73 (0.29) | 72 (0.04) | 219 (0.10) |
Dysstasia | 1 (0.02) | 13 (0.14) | 48 (0.20) | 0 | 19 (0.08) | 81 (0.05) | 169 (0.08) |
Dysuria | 2 (0.04) | 5 (0.05) | 15 (0.06) | 0 | 25 (0.10) | 67 (0.04) | 117 (0.05) |
Ear discomfort | 0 | 2 (0.02) | 26 (0.11) | 0 | 18 (0.07) | 80 (0.05) | 129 (0.06) |
Ear infection | 1 (0.02) | 5 (0.05) | 21 (0.09) | 0 | 8 (0.03) | 104 (0.06) | 142 (0.06) |
Ear pain | 0 | 16 (0.17) | 266 (1.10) | 0 | 66 (0.27) | 1404 (0.87) | 1756 (0.78) |
Ear swelling | 0 | 1 (0.01) | 2 (0.01) | 0 | 8 (0.03) | 50 (0.03) | 61 (0.03) |
Ecchymosis | 0 | 9 (0.10) | 7 (0.03) | 0 | 38 (0.15) | 53 (0.03) | 114 (0.05) |
Eczema | 1 (0.02) | 7 (0.08) | 32 (0.13) | 0 | 17 (0.07) | 198 (0.12) | 255 (0.11) |
Electric shock sensation | 1 (0.02) | 3 (0.03) | 25 (0.10) | 0 | 8 (0.03) | 73 (0.05) | 110 (0.05) |
Embolism | 32 (0.66) | 100 (1.09) | 30 (0.12) | 0 | 80 (0.32) | 112 (0.07) | 360 (0.16) |
Emotional disorder | 0 | 0 | 16 (0.07) | 0 | 2 (0.01) | 66 (0.04) | 85 (0.04) |
Emotional distress | 0 | 6 (0.07) | 21 (0.09) | 0 | 5 (0.02) | 57 (0.04) | 91 (0.04) |
Encephalitis | 5 (0.10) | 36 (0.39) | 13 (0.05) | 0 | 66 (0.27) | 19 (0.01) | 141 (0.06) |
Endometriosis | 0 | 0 | 8 (0.03) | 0 | 7 (0.03) | 54 (0.03) | 69 (0.03) |
Enuresis | 0 | 2 (0.02) | 8 (0.03) | 0 | 2 (0.01) | 42 (0.03) | 54 (0.02) |
Epilepsy | 6 (0.12) | 55 (0.60) | 52 (0.21) | 0 | 137 (0.55) | 201 (0.12) | 459 (0.20) |
Epistaxis | 12 (0.25) | 82 (0.89) | 149 (0.61) | 1 (0.64) | 191 (0.77) | 1177 (0.73) | 1626 (0.73) |
Erectile dysfunction | 1 (0.02) | 7 (0.08) | 30 (0.12) | 0 | 5 (0.02) | 43 (0.03) | 86 (0.04) |
Eructation | 1 (0.02) | 5 (0.05) | 18 (0.07) | 0 | 3 (0.01) | 66 (0.04) | 93 (0.04) |
Erythema | 7 (0.14) | 69 (0.75) | 169 (0.70) | 2 (1.27) | 168 (0.68) | 1656 (1.03) | 2090 (0.93) |
Erythema multiforme | 0 | 5 (0.05) | 1 (0.00) | 0 | 11 (0.04) | 49 (0.03) | 67 (0.03) |
Exercise tolerance decreased | 0 | 8 (0.09) | 21 (0.09) | 0 | 23 (0.09) | 39 (0.02) | 100 (0.04) |
Exposure during pregnancy | 5 (0.10) | 7 (0.08) | 3 (0.01) | 4 (2.55) | 20 (0.08) | 40 (0.02) | 91 (0.04) |
Exposure via breast milk | 0 | 1 (0.01) | 4 (0.02) | 0 | 0 | 52 (0.03) | 57 (0.03) |
Extensive swelling of vaccinated limb | 0 | 4 (0.04) | 182 (0.75) | 0 | 6 (0.02) | 40 (0.02) | 233 (0.10) |
Extrasystoles | 1 (0.02) | 7 (0.08) | 28 (0.12) | 1 (0.64) | 20 (0.08) | 127 (0.08) | 186 (0.08) |
Eye disorder | 0 | 2 (0.02) | 9 (0.04) | 0 | 9 (0.04) | 30 (0.02) | 52 (0.02) |
Eye haemorrhage | 0 | 2 (0.02) | 24 (0.10) | 0 | 15 (0.06) | 91 (0.06) | 136 (0.06) |
Eye injury | 0 | 5 (0.05) | 20 (0.08) | 0 | 4 (0.02) | 25 (0.02) | 55 (0.02) |
Eye irritation | 0 | 6 (0.07) | 35 (0.14) | 0 | 10 (0.04) | 142 (0.09) | 194 (0.09) |
Eye movement disorder | 0 | 6 (0.07) | 12 (0.05) | 0 | 9 (0.04) | 32 (0.02) | 61 (0.03) |
Eye pain | 2 (0.04) | 43 (0.47) | 453 (1.87) | 0 | 107 (0.43) | 2213 (1.37) | 2825 (1.26) |
Eye pruritus | 0 | 10 (0.11) | 25 (0.10) | 0 | 12 (0.05) | 167 (0.10) | 215 (0.10) |
Eye swelling | 0 | 16 (0.17) | 48 (0.20) | 0 | 28 (0.11) | 356 (0.22) | 449 (0.20) |
Eyelid oedema | 1 (0.02) | 2 (0.02) | 7 (0.03) | 0 | 14 (0.06) | 35 (0.02) | 60 (0.03) |
Eyelid ptosis | 1 (0.02) | 5 (0.05) | 16 (0.07) | 0 | 19 (0.08) | 40 (0.02) | 85 (0.04) |
Face oedema | 1 (0.02) | 21 (0.23) | 10 (0.04) | 0 | 29 (0.12) | 72 (0.04) | 134 (0.06) |
Facial pain | 0 | 5 (0.05) | 60 (0.25) | 0 | 16 (0.06) | 191 (0.12) | 274 (0.12) |
Facial paralysis | 13 (0.27) | 49 (0.53) | 126 (0.52) | 0 | 210 (0.85) | 321 (0.20) | 754 (0.34) |
Facial paresis | 5 (0.10) | 27 (0.29) | 49 (0.20) | 0 | 106 (0.43) | 101 (0.06) | 297 (0.13) |
Faeces discoloured | 0 | 2 (0.02) | 8 (0.03) | 0 | 8 (0.03) | 30 (0.02) | 51 (0.02) |
Fall | 27 (0.55) | 46 (0.50) | 58 (0.24) | 0 | 110 (0.44) | 188 (0.12) | 452 (0.20) |
Fatigue | 146 (2.99) | 506 (5.49) | 7870 (32.46) | 5 (3.18) | 1594 (6.43) | 35059 (21.78) | 45307 (20.20) |
Fear | 0 | 6 (0.07) | 18 (0.07) | 0 | 5 (0.02) | 38 (0.02) | 68 (0.03) |
Febrile convulsion | 2 (0.04) | 4 (0.04) | 17 (0.07) | 0 | 22 (0.09) | 103 (0.06) | 151 (0.07) |
Feeding disorder | 3 (0.06) | 9 (0.10) | 53 (0.22) | 0 | 11 (0.04) | 147 (0.09) | 226 (0.10) |
Feeling abnormal | 15 (0.31) | 55 (0.60) | 429 (1.77) | 0 | 116 (0.47) | 2073 (1.29) | 2709 (1.21) |
Feeling cold | 7 (0.14) | 43 (0.47) | 464 (1.91) | 0 | 125 (0.50) | 3710 (2.30) | 4353 (1.94) |
Feeling drunk | 0 | 1 (0.01) | 17 (0.07) | 0 | 2 (0.01) | 82 (0.05) | 102 (0.05) |
Feeling hot | 5 (0.10) | 42 (0.46) | 201 (0.83) | 0 | 114 (0.46) | 1552 (0.96) | 1929 (0.86) |
Feeling of body temperature change | 4 (0.08) | 3 (0.03) | 118 (0.49) | 0 | 26 (0.10) | 655 (0.41) | 807 (0.36) |
Fibrin D dimer increased | 40 (0.82) | 74 (0.80) | 16 (0.07) | 0 | 308 (1.24) | 165 (0.10) | 759 (0.34) |
Fibromyalgia | 0 | 3 (0.03) | 102 (0.42) | 0 | 15 (0.06) | 189 (0.12) | 312 (0.14) |
Flank pain | 2 (0.04) | 3 (0.03) | 19 (0.08) | 0 | 19 (0.08) | 59 (0.04) | 108 (0.05) |
Flatulence | 0 | 5 (0.05) | 38 (0.16) | 0 | 10 (0.04) | 277 (0.17) | 332 (0.15) |
Fluid retention | 2 (0.04) | 5 (0.05) | 18 (0.07) | 0 | 10 (0.04) | 51 (0.03) | 86 (0.04) |
Flushing | 1 (0.02) | 20 (0.22) | 67 (0.28) | 0 | 46 (0.19) | 450 (0.28) | 587 (0.26) |
Food aversion | 0 | 1 (0.01) | 9 (0.04) | 0 | 3 (0.01) | 41 (0.03) | 54 (0.02) |
Formication | 0 | 1 (0.01) | 12 (0.05) | 0 | 6 (0.02) | 67 (0.04) | 86 (0.04) |
Freezing phenomenon | 0 | 2 (0.02) | 12 (0.05) | 0 | 5 (0.02) | 114 (0.07) | 133 (0.06) |
Gait disturbance | 12 (0.25) | 47 (0.51) | 251 (1.04) | 1 (0.64) | 173 (0.70) | 329 (0.20) | 841 (0.38) |
Gait inability | 5 (0.10) | 17 (0.18) | 104 (0.43) | 0 | 44 (0.18) | 110 (0.07) | 297 (0.13) |
Gastritis | 2 (0.04) | 3 (0.03) | 31 (0.13) | 0 | 16 (0.06) | 71 (0.04) | 124 (0.06) |
Gastroenteritis viral | 1 (0.02) | 0 | 4 (0.02) | 0 | 3 (0.01) | 49 (0.03) | 58 (0.03) |
Gastrointestinal disorder | 0 | 1 (0.01) | 30 (0.12) | 0 | 8 (0.03) | 44 (0.03) | 85 (0.04) |
Gastrointestinal haemorrhage | 16 (0.33) | 11 (0.12) | 7 (0.03) | 0 | 12 (0.05) | 15 (0.01) | 66 (0.03) |
Gastrointestinal pain | 0 | 0 | 54 (0.22) | 0 | 35 (0.14) | 232 (0.14) | 322 (0.14) |
Gastrooesophageal reflux disease | 1 (0.02) | 1 (0.01) | 40 (0.16) | 0 | 10 (0.04) | 147 (0.09) | 201 (0.09) |
General physical health deterioration | 24 (0.49) | 13 (0.14) | 15 (0.06) | 0 | 56 (0.23) | 21 (0.01) | 139 (0.06) |
Generalised tonic-clonic seizure | 4 (0.08) | 33 (0.36) | 11 (0.05) | 0 | 57 (0.23) | 55 (0.03) | 166 (0.07) |
Genital herpes | 0 | 0 | 9 (0.04) | 0 | 1 (0.00) | 52 (0.03) | 62 (0.03) |
Giant cell arteritis | 2 (0.04) | 9 (0.10) | 9 (0.04) | 0 | 20 (0.08) | 42 (0.03) | 83 (0.04) |
Gingival bleeding | 0 | 14 (0.15) | 14 (0.06) | 0 | 23 (0.09) | 108 (0.07) | 164 (0.07) |
Gingival pain | 0 | 1 (0.01) | 21 (0.09) | 1 (0.64) | 2 (0.01) | 143 (0.09) | 168 (0.07) |
Glossodynia | 0 | 2 (0.02) | 23 (0.09) | 0 | 3 (0.01) | 137 (0.09) | 165 (0.07) |
Gout | 1 (0.02) | 2 (0.02) | 26 (0.11) | 0 | 7 (0.03) | 117 (0.07) | 153 (0.07) |
Groin pain | 2 (0.04) | 8 (0.09) | 43 (0.18) | 0 | 18 (0.07) | 138 (0.09) | 211 (0.09) |
Guillain-Barre syndrome | 22 (0.45) | 205 (2.23) | 212 (0.87) | 3 (1.91) | 661 (2.67) | 236 (0.15) | 1375 (0.61) |
Haematemesis | 15 (0.31) | 17 (0.18) | 8 (0.03) | 0 | 43 (0.17) | 74 (0.05) | 164 (0.07) |
Haematochezia | 3 (0.06) | 7 (0.08) | 9 (0.04) | 0 | 33 (0.13) | 93 (0.06) | 147 (0.07) |
Haematoma | 6 (0.12) | 42 (0.46) | 41 (0.17) | 1 (0.64) | 103 (0.42) | 192 (0.12) | 396 (0.18) |
Haematuria | 2 (0.04) | 9 (0.10) | 7 (0.03) | 0 | 26 (0.10) | 63 (0.04) | 114 (0.05) |
Haemoglobin decreased | 5 (0.10) | 9 (0.10) | 6 (0.02) | 0 | 13 (0.05) | 16 (0.01) | 56 (0.02) |
Haemoptysis | 14 (0.29) | 35 (0.38) | 9 (0.04) | 0 | 50 (0.20) | 80 (0.05) | 196 (0.09) |
Haemorrhage | 27 (0.55) | 102 (1.11) | 83 (0.34) | 6 (3.82) | 110 (0.44) | 758 (0.47) | 1103 (0.49) |
Haemorrhage intracranial | 48 (0.98) | 29 (0.31) | 6 (0.02) | 0 | 13 (0.05) | 14 (0.01) | 120 (0.05) |
Haemorrhage urinary tract | 1 (0.02) | 10 (0.11) | 4 (0.02) | 0 | 8 (0.03) | 34 (0.02) | 58 (0.03) |
Haemorrhagic stroke | 35 (0.72) | 34 (0.37) | 6 (0.02) | 0 | 25 (0.10) | 15 (0.01) | 119 (0.05) |
Haemorrhoids | 1 (0.02) | 1 (0.01) | 8 (0.03) | 0 | 2 (0.01) | 47 (0.03) | 60 (0.03) |
Hallucination | 1 (0.02) | 19 (0.21) | 145 (0.60) | 0 | 39 (0.16) | 653 (0.41) | 864 (0.39) |
Hallucination, visual | 0 | 4 (0.04) | 8 (0.03) | 0 | 5 (0.02) | 44 (0.03) | 62 (0.03) |
Hangover | 0 | 0 | 23 (0.09) | 0 | 2 (0.01) | 121 (0.08) | 148 (0.07) |
Head discomfort | 2 (0.04) | 22 (0.24) | 174 (0.72) | 0 | 75 (0.30) | 499 (0.31) | 782 (0.35) |
Head injury | 3 (0.06) | 17 (0.18) | 11 (0.05) | 0 | 14 (0.06) | 22 (0.01) | 71 (0.03) |
Headache | 292 (5.99) | 1055 (11.45) | 9443 (38.95) | 17 (10.83) | 3970 (16.02) | 56135 (34.87) | 71181 (31.74) |
Heart rate | 0 | 19 (0.21) | 79 (0.33) | 0 | 66 (0.27) | 746 (0.46) | 910 (0.41) |
Heart rate abnormal | 1 (0.02) | 2 (0.02) | 10 (0.04) | 0 | 13 (0.05) | 47 (0.03) | 76 (0.03) |
Heart rate decreased | 2 (0.04) | 14 (0.15) | 16 (0.07) | 0 | 29 (0.12) | 81 (0.05) | 142 (0.06) |
Heart rate increased | 3 (0.06) | 77 (0.84) | 245 (1.01) | 3 (1.91) | 186 (0.75) | 1523 (0.95) | 2054 (0.92) |
Heart rate irregular | 1 (0.02) | 17 (0.18) | 45 (0.19) | 1 (0.64) | 36 (0.15) | 159 (0.10) | 259 (0.12) |
Heavy menstrual bleeding | 0 | 23 (0.25) | 256 (1.06) | 2 (1.27) | 102 (0.41) | 2562 (1.59) | 2950 (1.32) |
Hemiparaesthesia | 1 (0.02) | 2 (0.02) | 4 (0.02) | 0 | 17 (0.07) | 32 (0.02) | 59 (0.03) |
Hemiparesis | 34 (0.70) | 68 (0.74) | 46 (0.19) | 0 | 111 (0.45) | 120 (0.07) | 422 (0.19) |
Hemiplegia | 8 (0.16) | 33 (0.36) | 23 (0.09) | 0 | 40 (0.16) | 58 (0.04) | 187 (0.08) |
Hemiplegic migraine | 0 | 3 (0.03) | 21 (0.09) | 0 | 8 (0.03) | 22 (0.01) | 55 (0.02) |
Heparin-induced thrombocytopenia test positive | 7 (0.14) | 8 (0.09) | 0 | 0 | 29 (0.12) | 2 (0.00) | 51 (0.02) |
Hepatic pain | 0 | 3 (0.03) | 22 (0.09) | 0 | 3 (0.01) | 50 (0.03) | 78 (0.03) |
Hepatitis | 1 (0.02) | 6 (0.07) | 2 (0.01) | 0 | 21 (0.08) | 28 (0.02) | 59 (0.03) |
Herpes zoster | 0 | 17 (0.18) | 161 (0.66) | 0 | 115 (0.46) | 1246 (0.77) | 1539 (0.69) |
Hospitalisation | 2 (0.04) | 3 (0.03) | 4 (0.02) | 0 | 61 (0.25) | 0 | 76 (0.03) |
Hot flush | 2 (0.04) | 12 (0.13) | 188 (0.78) | 0 | 55 (0.22) | 1392 (0.86) | 1654 (0.74) |
Hunger | 0 | 2 (0.02) | 3 (0.01) | 0 | 1 (0.00) | 46 (0.03) | 52 (0.02) |
Hyperacusis | 0 | 8 (0.09) | 56 (0.23) | 0 | 23 (0.09) | 86 (0.05) | 173 (0.08) |
Hyperaesthesia | 0 | 4 (0.04) | 34 (0.14) | 1 (0.64) | 25 (0.10) | 185 (0.11) | 250 (0.11) |
Hyperglycaemia | 5 (0.10) | 16 (0.17) | 15 (0.06) | 0 | 26 (0.10) | 95 (0.06) | 161 (0.07) |
Hyperhidrosis | 22 (0.45) | 87 (0.94) | 1028 (4.24) | 1 (0.64) | 300 (1.21) | 6605 (4.10) | 8071 (3.60) |
Hyperpyrexia | 5 (0.10) | 13 (0.14) | 16 (0.07) | 0 | 43 (0.17) | 738 (0.46) | 816 (0.36) |
Hypersensitivity | 10 (0.21) | 98 (1.06) | 187 (0.77) | 0 | 242 (0.98) | 969 (0.60) | 1521 (0.68) |
Hypersomnia | 1 (0.02) | 7 (0.08) | 33 (0.14) | 0 | 14 (0.06) | 148 (0.09) | 206 (0.09) |
Hypertension | 51 (1.05) | 168 (1.82) | 187 (0.77) | 1 (0.64) | 449 (1.81) | 876 (0.54) | 1779 (0.79) |
Hypertensive crisis | 4 (0.08) | 13 (0.14) | 2 (0.01) | 0 | 66 (0.27) | 110 (0.07) | 201 (0.09) |
Hyperthyroidism | 0 | 11 (0.12) | 13 (0.05) | 1 (0.64) | 12 (0.05) | 49 (0.03) | 87 (0.04) |
Hyperventilation | 1 (0.02) | 4 (0.04) | 13 (0.05) | 0 | 26 (0.10) | 72 (0.04) | 118 (0.05) |
Hypoacusis | 1 (0.02) | 6 (0.07) | 77 (0.32) | 0 | 21 (0.08) | 170 (0.11) | 277 (0.12) |
Hypoaesthesia | 20 (0.41) | 163 (1.77) | 851 (3.51) | 1 (0.64) | 582 (2.35) | 3369 (2.09) | 5033 (2.24) |
Hypoaesthesia oral | 1 (0.02) | 17 (0.18) | 50 (0.21) | 0 | 56 (0.23) | 349 (0.22) | 479 (0.21) |
Hypoglycaemia | 7 (0.14) | 9 (0.10) | 8 (0.03) | 0 | 20 (0.08) | 67 (0.04) | 114 (0.05) |
Hypokinesia | 2 (0.04) | 6 (0.07) | 38 (0.16) | 0 | 28 (0.11) | 54 (0.03) | 144 (0.06) |
Hypomenorrhoea | 0 | 0 | 23 (0.09) | 0 | 2 (0.01) | 144 (0.09) | 169 (0.08) |
Hypopnoea | 3 (0.06) | 15 (0.16) | 30 (0.12) | 0 | 9 (0.04) | 148 (0.09) | 208 (0.09) |
Hypotension | 48 (0.98) | 78 (0.85) | 100 (0.41) | 0 | 164 (0.66) | 415 (0.26) | 839 (0.37) |
Hypothermia | 8 (0.16) | 8 (0.09) | 10 (0.04) | 0 | 6 (0.02) | 71 (0.04) | 107 (0.05) |
Hypothyroidism | 1 (0.02) | 4 (0.04) | 11 (0.05) | 0 | 6 (0.02) | 45 (0.03) | 69 (0.03) |
Hypotonia | 2 (0.04) | 10 (0.11) | 13 (0.05) | 0 | 89 (0.36) | 32 (0.02) | 150 (0.07) |
Hypovolaemic shock | 4 (0.08) | 3 (0.03) | 0 | 0 | 3 (0.01) | 62 (0.04) | 75 (0.03) |
Hypoxia | 17 (0.35) | 32 (0.35) | 6 (0.02) | 0 | 47 (0.19) | 26 (0.02) | 144 (0.06) |
Illness | 12 (0.25) | 56 (0.61) | 467 (1.93) | 1 (0.64) | 166 (0.67) | 3424 (2.13) | 4132 (1.84) |
Immobile | 2 (0.04) | 6 (0.07) | 20 (0.08) | 0 | 11 (0.04) | 26 (0.02) | 67 (0.03) |
Immune system disorder | 2 (0.04) | 3 (0.03) | 15 (0.06) | 0 | 9 (0.04) | 26 (0.02) | 57 (0.03) |
Immune thrombocytopenia | 38 (0.78) | 143 (1.55) | 13 (0.05) | 0 | 309 (1.25) | 149 (0.09) | 693 (0.31) |
Immunisation | 4 (0.08) | 6 (0.07) | 20 (0.08) | 0 | 9 (0.04) | 137 (0.09) | 176 (0.08) |
Impaired work ability | 0 | 7 (0.08) | 119 (0.49) | 0 | 25 (0.10) | 141 (0.09) | 305 (0.14) |
Incontinence | 3 (0.06) | 11 (0.12) | 24 (0.10) | 0 | 15 (0.06) | 40 (0.02) | 97 (0.04) |
Increased tendency to bruise | 0 | 5 (0.05) | 29 (0.12) | 0 | 10 (0.04) | 65 (0.04) | 111 (0.05) |
Infarction | 22 (0.45) | 17 (0.18) | 2 (0.01) | 0 | 29 (0.12) | 9 (0.01) | 81 (0.04) |
Infection | 8 (0.16) | 23 (0.25) | 52 (0.21) | 0 | 59 (0.24) | 292 (0.18) | 444 (0.20) |
Infectious mononucleosis | 0 | 0 | 19 (0.08) | 0 | 4 (0.02) | 34 (0.02) | 57 (0.03) |
Inflammation | 6 (0.12) | 34 (0.37) | 160 (0.66) | 1 (0.64) | 77 (0.31) | 477 (0.30) | 764 (0.34) |
Influenza | 5 (0.10) | 28 (0.30) | 565 (2.33) | 0 | 326 (1.32) | 4794 (2.98) | 5721 (2.55) |
Influenza like illness | 24 (0.49) | 60 (0.65) | 1012 (4.17) | 0 | 501 (2.02) | 8167 (5.07) | 9785 (4.36) |
Initial insomnia | 0 | 1 (0.01) | 5 (0.02) | 0 | 0 | 49 (0.03) | 55 (0.02) |
Injected limb mobility decreased | 1 (0.02) | 1 (0.01) | 54 (0.22) | 0 | 2 (0.01) | 71 (0.04) | 129 (0.06) |
Injection related reaction | 0 | 1 (0.01) | 36 (0.15) | 0 | 5 (0.02) | 448 (0.28) | 491 (0.22) |
Injection site bruising | 0 | 1 (0.01) | 11 (0.05) | 0 | 1 (0.00) | 80 (0.05) | 94 (0.04) |
Injection site erythema | 0 | 7 (0.08) | 62 (0.26) | 0 | 44 (0.18) | 353 (0.22) | 469 (0.21) |
Injection site mass | 0 | 2 (0.02) | 54 (0.22) | 0 | 8 (0.03) | 779 (0.48) | 844 (0.38) |
Injection site pain | 9 (0.18) | 30 (0.33) | 550 (2.27) | 0 | 232 (0.94) | 3169 (1.97) | 4001 (1.78) |
Injection site pruritus | 0 | 1 (0.01) | 20 (0.08) | 0 | 3 (0.01) | 170 (0.11) | 195 (0.09) |
Injection site rash | 0 | 0 | 10 (0.04) | 1 (0.64) | 2 (0.01) | 151 (0.09) | 165 (0.07) |
Injection site reaction | 3 (0.06) | 5 (0.05) | 1273 (5.25) | 0 | 38 (0.15) | 102 (0.06) | 1426 (0.64) |
Injection site swelling | 1 (0.02) | 8 (0.09) | 65 (0.27) | 0 | 43 (0.17) | 180 (0.11) | 300 (0.13) |
Injection site warmth | 0 | 2 (0.02) | 39 (0.16) | 0 | 6 (0.02) | 210 (0.13) | 258 (0.12) |
Insomnia | 6 (0.12) | 43 (0.47) | 482 (1.99) | 0 | 92 (0.37) | 2143 (1.33) | 2776 (1.24) |
Interchange of vaccine products | 7 (0.14) | 9 (0.10) | 21 (0.09) | 0 | 13 (0.05) | 134 (0.08) | 189 (0.08) |
Intermenstrual bleeding | 0 | 3 (0.03) | 19 (0.08) | 0 | 19 (0.08) | 338 (0.21) | 380 (0.17) |
International normalised ratio increased | 2 (0.04) | 10 (0.11) | 6 (0.02) | 0 | 5 (0.02) | 46 (0.03) | 71 (0.03) |
Interstitial lung disease | 8 (0.16) | 9 (0.10) | 7 (0.03) | 0 | 12 (0.05) | 20 (0.01) | 57 (0.03) |
Intestinal ischaemia | 21 (0.43) | 28 (0.30) | 3 (0.01) | 0 | 14 (0.06) | 10 (0.01) | 77 (0.03) |
Intracranial pressure increased | 19 (0.39) | 12 (0.13) | 7 (0.03) | 0 | 14 (0.06) | 15 (0.01) | 75 (0.03) |
Irritability | 4 (0.08) | 10 (0.11) | 29 (0.12) | 0 | 24 (0.10) | 216 (0.13) | 286 (0.13) |
Irritable bowel syndrome | 0 | 3 (0.03) | 20 (0.08) | 0 | 11 (0.04) | 95 (0.06) | 130 (0.06) |
Ischaemia | 5 (0.10) | 15 (0.16) | 9 (0.04) | 0 | 20 (0.08) | 6 (0.00) | 56 (0.02) |
Ischaemic cerebral infarction | 4 (0.08) | 24 (0.26) | 4 (0.02) | 0 | 16 (0.06) | 4 (0.00) | 53 (0.02) |
Ischaemic stroke | 43 (0.88) | 161 (1.75) | 71 (0.29) | 0 | 295 (1.19) | 77 (0.05) | 659 (0.29) |
Jaundice | 7 (0.14) | 7 (0.08) | 1 (0.00) | 1 (0.64) | 27 (0.11) | 29 (0.02) | 74 (0.03) |
Joint lock | 1 (0.02) | 1 (0.01) | 11 (0.05) | 0 | 4 (0.02) | 43 (0.03) | 60 (0.03) |
Joint stiffness | 0 | 3 (0.03) | 87 (0.36) | 0 | 16 (0.06) | 288 (0.18) | 394 (0.18) |
Joint swelling | 4 (0.08) | 22 (0.24) | 186 (0.77) | 0 | 68 (0.27) | 635 (0.39) | 922 (0.41) |
Jugular vein thrombosis | 7 (0.14) | 24 (0.26) | 2 (0.01) | 0 | 30 (0.12) | 20 (0.01) | 87 (0.04) |
Kidney infection | 1 (0.02) | 6 (0.07) | 12 (0.05) | 0 | 11 (0.04) | 41 (0.03) | 72 (0.03) |
Labyrinthitis | 1 (0.02) | 2 (0.02) | 27 (0.11) | 0 | 20 (0.08) | 117 (0.07) | 168 (0.07) |
Lacrimation increased | 0 | 3 (0.03) | 35 (0.14) | 0 | 21 (0.08) | 173 (0.11) | 232 (0.10) |
Laryngeal oedema | 1 (0.02) | 24 (0.26) | 0 | 0 | 22 (0.09) | 46 (0.03) | 95 (0.04) |
Lethargy | 31 (0.64) | 61 (0.66) | 415 (1.71) | 0 | 121 (0.49) | 3200 (1.99) | 3855 (1.72) |
Limb discomfort | 2 (0.04) | 33 (0.36) | 234 (0.97) | 0 | 431 (1.74) | 1393 (0.87) | 2105 (0.94) |
Limb injury | 2 (0.04) | 3 (0.03) | 92 (0.38) | 0 | 5 (0.02) | 199 (0.12) | 302 (0.13) |
Lip dry | 0 | 2 (0.02) | 4 (0.02) | 0 | 2 (0.01) | 48 (0.03) | 56 (0.02) |
Lip oedema | 2 (0.04) | 9 (0.10) | 4 (0.02) | 0 | 12 (0.05) | 39 (0.02) | 68 (0.03) |
Lip swelling | 2 (0.04) | 44 (0.48) | 44 (0.18) | 0 | 65 (0.26) | 535 (0.33) | 691 (0.31) |
Listless | 4 (0.08) | 0 | 16 (0.07) | 0 | 2 (0.01) | 84 (0.05) | 106 (0.05) |
Livedo reticularis | 1 (0.02) | 4 (0.04) | 5 (0.02) | 0 | 10 (0.04) | 46 (0.03) | 70 (0.03) |
Liver function test abnormal | 2 (0.04) | 6 (0.07) | 8 (0.03) | 0 | 16 (0.06) | 21 (0.01) | 62 (0.03) |
Local reaction | 4 (0.08) | 1 (0.01) | 11 (0.05) | 0 | 30 (0.12) | 31 (0.02) | 78 (0.03) |
Localised infection | 0 | 1 (0.01) | 5 (0.02) | 0 | 11 (0.04) | 73 (0.05) | 91 (0.04) |
Loss of consciousness | 84 (1.72) | 173 (1.88) | 117 (0.48) | 0 | 352 (1.42) | 954 (0.59) | 1721 (0.77) |
Loss of control of legs | 0 | 4 (0.04) | 10 (0.04) | 0 | 10 (0.04) | 36 (0.02) | 61 (0.03) |
Loss of personal independence in daily activities | 0 | 6 (0.07) | 75 (0.31) | 0 | 7 (0.03) | 44 (0.03) | 138 (0.06) |
Lower respiratory tract infection | 19 (0.39) | 25 (0.27) | 45 (0.19) | 0 | 36 (0.15) | 161 (0.10) | 294 (0.13) |
Lung disorder | 3 (0.06) | 7 (0.08) | 7 (0.03) | 0 | 23 (0.09) | 8 (0.00) | 55 (0.02) |
Lymph node pain | 1 (0.02) | 2 (0.02) | 50 (0.21) | 0 | 14 (0.06) | 384 (0.24) | 451 (0.20) |
Lymphadenopathy | 3 (0.06) | 42 (0.46) | 459 (1.89) | 3 (1.91) | 150 (0.61) | 3098 (1.92) | 3768 (1.68) |
Lymphoedema | 0 | 4 (0.04) | 11 (0.05) | 0 | 2 (0.01) | 49 (0.03) | 67 (0.03) |
Malaise | 179 (3.67) | 326 (3.54) | 2801 (11.55) | 2 (1.27) | 912 (3.68) | 8671 (5.39) | 12987 (5.79) |
Mass | 0 | 2 (0.02) | 7 (0.03) | 0 | 4 (0.02) | 38 (0.02) | 54 (0.02) |
Maternal exposure during breast feeding | 1 (0.02) | 12 (0.13) | 62 (0.26) | 7 (4.46) | 12 (0.05) | 799 (0.50) | 896 (0.40) |
Maternal exposure during pregnancy | 4 (0.08) | 21 (0.23) | 31 (0.13) | 56 (35.67) | 38 (0.15) | 184 (0.11) | 344 (0.15) |
Memory impairment | 3 (0.06) | 18 (0.20) | 134 (0.55) | 0 | 49 (0.20) | 243 (0.15) | 460 (0.21) |
Meningitis | 3 (0.06) | 6 (0.07) | 3 (0.01) | 0 | 27 (0.11) | 23 (0.01) | 66 (0.03) |
Menstrual disorder | 1 (0.02) | 7 (0.08) | 82 (0.34) | 5 (3.18) | 22 (0.09) | 694 (0.43) | 812 (0.36) |
Menstruation delayed | 0 | 5 (0.05) | 111 (0.46) | 1 (0.64) | 19 (0.08) | 1054 (0.65) | 1190 (0.53) |
Menstruation irregular | 0 | 5 (0.05) | 112 (0.46) | 4 (2.55) | 22 (0.09) | 880 (0.55) | 1025 (0.46) |
Mental fatigue | 0 | 10 (0.11) | 95 (0.39) | 0 | 12 (0.05) | 325 (0.20) | 443 (0.20) |
Mental impairment | 2 (0.04) | 5 (0.05) | 44 (0.18) | 0 | 8 (0.03) | 84 (0.05) | 146 (0.07) |
Mesenteric vein thrombosis | 12 (0.25) | 32 (0.35) | 2 (0.01) | 0 | 41 (0.17) | 10 (0.01) | 107 (0.05) |
Micturition urgency | 1 (0.02) | 2 (0.02) | 13 (0.05) | 0 | 9 (0.04) | 52 (0.03) | 77 (0.03) |
Middle insomnia | 0 | 2 (0.02) | 6 (0.02) | 0 | 3 (0.01) | 53 (0.03) | 65 (0.03) |
Migraine | 4 (0.08) | 87 (0.94) | 1189 (4.90) | 0 | 303 (1.22) | 5341 (3.32) | 6939 (3.09) |
Migraine with aura | 0 | 3 (0.03) | 73 (0.30) | 0 | 23 (0.09) | 258 (0.16) | 359 (0.16) |
Miliaria | 0 | 1 (0.01) | 18 (0.07) | 0 | 3 (0.01) | 104 (0.06) | 127 (0.06) |
Mobility decreased | 6 (0.12) | 12 (0.13) | 111 (0.46) | 0 | 83 (0.33) | 84 (0.05) | 311 (0.14) |
Monoparesis | 3 (0.06) | 6 (0.07) | 31 (0.13) | 0 | 28 (0.11) | 103 (0.06) | 177 (0.08) |
Monoplegia | 2 (0.04) | 10 (0.11) | 52 (0.21) | 0 | 39 (0.16) | 151 (0.09) | 262 (0.12) |
Mood altered | 1 (0.02) | 2 (0.02) | 9 (0.04) | 0 | 5 (0.02) | 61 (0.04) | 81 (0.04) |
Mood swings | 1 (0.02) | 4 (0.04) | 23 (0.09) | 0 | 2 (0.01) | 81 (0.05) | 111 (0.05) |
Motion sickness | 0 | 2 (0.02) | 22 (0.09) | 0 | 4 (0.02) | 86 (0.05) | 115 (0.05) |
Motor dysfunction | 3 (0.06) | 8 (0.09) | 17 (0.07) | 0 | 27 (0.11) | 18 (0.01) | 80 (0.04) |
Mouth haemorrhage | 1 (0.02) | 6 (0.07) | 4 (0.02) | 0 | 9 (0.04) | 40 (0.02) | 64 (0.03) |
Mouth swelling | 0 | 13 (0.14) | 8 (0.03) | 0 | 10 (0.04) | 82 (0.05) | 113 (0.05) |
Mouth ulceration | 0 | 2 (0.02) | 56 (0.23) | 0 | 11 (0.04) | 374 (0.23) | 444 (0.20) |
Movement disorder | 0 | 13 (0.14) | 41 (0.17) | 0 | 61 (0.25) | 62 (0.04) | 184 (0.08) |
Multiple organ dysfunction syndrome | 57 (1.17) | 10 (0.11) | 0 | 0 | 6 (0.02) | 2 (0.00) | 82 (0.04) |
Multiple sclerosis | 1 (0.02) | 0 | 25 (0.10) | 1 (0.64) | 14 (0.06) | 52 (0.03) | 95 (0.04) |
Multiple sclerosis relapse | 0 | 0 | 24 (0.10) | 0 | 14 (0.06) | 58 (0.04) | 97 (0.04) |
Muscle contractions involuntary | 0 | 1 (0.01) | 16 (0.07) | 0 | 2 (0.01) | 39 (0.02) | 58 (0.03) |
Muscle fatigue | 2 (0.04) | 8 (0.09) | 160 (0.66) | 0 | 16 (0.06) | 697 (0.43) | 885 (0.39) |
Muscle injury | 0 | 2 (0.02) | 9 (0.04) | 0 | 2 (0.01) | 41 (0.03) | 54 (0.02) |
Muscle rigidity | 1 (0.02) | 2 (0.02) | 14 (0.06) | 0 | 10 (0.04) | 48 (0.03) | 75 (0.03) |
Muscle spasms | 3 (0.06) | 64 (0.69) | 547 (2.26) | 3 (1.91) | 180 (0.73) | 2211 (1.37) | 3021 (1.35) |
Muscle tightness | 0 | 6 (0.07) | 31 (0.13) | 1 (0.64) | 19 (0.08) | 140 (0.09) | 199 (0.09) |
Muscle twitching | 1 (0.02) | 11 (0.12) | 96 (0.40) | 0 | 47 (0.19) | 287 (0.18) | 447 (0.20) |
Muscular weakness | 22 (0.45) | 107 (1.16) | 618 (2.55) | 1 (0.64) | 319 (1.29) | 1352 (0.84) | 2463 (1.10) |
Musculoskeletal chest pain | 1 (0.02) | 13 (0.14) | 66 (0.27) | 0 | 33 (0.13) | 280 (0.17) | 396 (0.18) |
Musculoskeletal discomfort | 0 | 4 (0.04) | 17 (0.07) | 0 | 11 (0.04) | 89 (0.06) | 122 (0.05) |
Musculoskeletal pain | 2 (0.04) | 9 (0.10) | 40 (0.16) | 0 | 43 (0.17) | 164 (0.10) | 260 (0.12) |
Musculoskeletal stiffness | 6 (0.12) | 19 (0.21) | 447 (1.84) | 0 | 88 (0.36) | 1482 (0.92) | 2051 (0.91) |
Myalgia | 66 (1.35) | 246 (2.67) | 5136 (21.18) | 4 (2.55) | 939 (3.79) | 19526 (12.13) | 25995 (11.59) |
Myelitis | 0 | 4 (0.04) | 16 (0.07) | 0 | 49 (0.20) | 15 (0.01) | 87 (0.04) |
Myelitis transverse | 1 (0.02) | 10 (0.11) | 64 (0.26) | 0 | 58 (0.23) | 40 (0.02) | 176 (0.08) |
Myocardial infarction | 197 (4.04) | 352 (3.82) | 42 (0.17) | 0 | 235 (0.95) | 149 (0.09) | 1001 (0.45) |
Myocardial ischaemia | 30 (0.62) | 5 (0.05) | 2 (0.01) | 0 | 8 (0.03) | 5 (0.00) | 57 (0.03) |
Myocarditis | 17 (0.35) | 86 (0.93) | 77 (0.32) | 0 | 188 (0.76) | 270 (0.17) | 663 (0.30) |
Myositis | 1 (0.02) | 8 (0.09) | 24 (0.10) | 0 | 10 (0.04) | 37 (0.02) | 83 (0.04) |
Nasal congestion | 4 (0.08) | 7 (0.08) | 61 (0.25) | 0 | 20 (0.08) | 305 (0.19) | 398 (0.18) |
Nasal discomfort | 0 | 0 | 8 (0.03) | 0 | 3 (0.01) | 75 (0.05) | 86 (0.04) |
Nasopharyngitis | 26 (0.53) | 12 (0.13) | 160 (0.66) | 0 | 162 (0.65) | 1110 (0.69) | 1478 (0.66) |
Nausea | 111 (2.28) | 319 (3.46) | 4602 (18.98) | 5 (3.18) | 1336 (5.39) | 24502 (15.22) | 30967 (13.81) |
Neck pain | 9 (0.18) | 54 (0.59) | 464 (1.91) | 0 | 191 (0.77) | 2044 (1.27) | 2774 (1.24) |
Nerve injury | 0 | 11 (0.12) | 67 (0.28) | 0 | 15 (0.06) | 89 (0.06) | 184 (0.08) |
Nervous system disorder | 7 (0.14) | 16 (0.17) | 59 (0.24) | 1 (0.64) | 42 (0.17) | 58 (0.04) | 192 (0.09) |
Nervousness | 0 | 7 (0.08) | 84 (0.35) | 0 | 20 (0.08) | 407 (0.25) | 519 (0.23) |
Neuralgia | 2 (0.04) | 17 (0.18) | 328 (1.35) | 0 | 109 (0.44) | 906 (0.56) | 1365 (0.61) |
Neurological symptom | 6 (0.12) | 11 (0.12) | 43 (0.18) | 0 | 29 (0.12) | 68 (0.04) | 160 (0.07) |
Neuropathy peripheral | 0 | 9 (0.10) | 78 (0.32) | 0 | 33 (0.13) | 171 (0.11) | 293 (0.13) |
Neutropenia | 0 | 9 (0.10) | 3 (0.01) | 0 | 17 (0.07) | 58 (0.04) | 89 (0.04) |
Night sweats | 2 (0.04) | 15 (0.16) | 159 (0.66) | 0 | 42 (0.17) | 1294 (0.80) | 1516 (0.68) |
Nightmare | 1 (0.02) | 6 (0.07) | 46 (0.19) | 0 | 5 (0.02) | 295 (0.18) | 353 (0.16) |
Ocular discomfort | 2 (0.04) | 2 (0.02) | 19 (0.08) | 1 (0.64) | 20 (0.08) | 58 (0.04) | 103 (0.05) |
Ocular hyperaemia | 1 (0.02) | 7 (0.08) | 34 (0.14) | 0 | 24 (0.10) | 231 (0.14) | 300 (0.13) |
Odynophagia | 4 (0.08) | 2 (0.02) | 1 (0.00) | 1 (0.64) | 7 (0.03) | 42 (0.03) | 59 (0.03) |
Oedema | 11 (0.23) | 33 (0.36) | 19 (0.08) | 0 | 75 (0.30) | 67 (0.04) | 214 (0.10) |
Oedema peripheral | 15 (0.31) | 63 (0.68) | 63 (0.26) | 0 | 102 (0.41) | 208 (0.13) | 465 (0.21) |
Off label use | 8 (0.16) | 12 (0.13) | 22 (0.09) | 0 | 18 (0.07) | 127 (0.08) | 193 (0.09) |
Oligomenorrhoea | 0 | 0 | 14 (0.06) | 0 | 2 (0.01) | 48 (0.03) | 64 (0.03) |
Ophthalmic herpes zoster | 0 | 1 (0.01) | 5 (0.02) | 0 | 11 (0.04) | 45 (0.03) | 62 (0.03) |
Ophthalmic vein thrombosis | 1 (0.02) | 7 (0.08) | 9 (0.04) | 0 | 18 (0.07) | 26 (0.02) | 64 (0.03) |
Optic neuritis | 0 | 4 (0.04) | 45 (0.19) | 0 | 44 (0.18) | 39 (0.02) | 136 (0.06) |
Oral candidiasis | 3 (0.06) | 0 | 4 (0.02) | 0 | 5 (0.02) | 39 (0.02) | 52 (0.02) |
Oral discomfort | 0 | 3 (0.03) | 9 (0.04) | 0 | 5 (0.02) | 81 (0.05) | 98 (0.04) |
Oral herpes | 1 (0.02) | 4 (0.04) | 45 (0.19) | 0 | 14 (0.06) | 399 (0.25) | 464 (0.21) |
Oral pain | 1 (0.02) | 1 (0.01) | 26 (0.11) | 1 (0.64) | 8 (0.03) | 207 (0.13) | 248 (0.11) |
Oropharyngeal pain | 22 (0.45) | 44 (0.48) | 389 (1.60) | 2 (1.27) | 175 (0.71) | 2831 (1.76) | 3468 (1.55) |
Orthostatic hypotension | 1 (0.02) | 4 (0.04) | 17 (0.07) | 0 | 9 (0.04) | 24 (0.01) | 55 (0.02) |
Osteoarthritis | 0 | 2 (0.02) | 36 (0.15) | 0 | 6 (0.02) | 56 (0.03) | 103 (0.05) |
Oxygen saturation | 13 (0.27) | 1 (0.01) | 1 (0.00) | 0 | 30 (0.12) | 17 (0.01) | 62 (0.03) |
Oxygen saturation decreased | 52 (1.07) | 30 (0.33) | 26 (0.11) | 0 | 164 (0.66) | 109 (0.07) | 401 (0.18) |
Pain | 62 (1.27) | 228 (2.48) | 2156 (8.89) | 4 (2.55) | 677 (2.73) | 11448 (7.11) | 14648 (6.53) |
Pain in extremity | 61 (1.25) | 317 (3.44) | 2414 (9.96) | 4 (2.55) | 852 (3.44) | 13752 (8.54) | 17485 (7.80) |
Pain in jaw | 1 (0.02) | 16 (0.17) | 94 (0.39) | 0 | 31 (0.13) | 400 (0.25) | 545 (0.24) |
Pain of skin | 0 | 3 (0.03) | 121 (0.50) | 0 | 21 (0.08) | 640 (0.40) | 786 (0.35) |
Pallor | 16 (0.33) | 35 (0.38) | 61 (0.25) | 0 | 40 (0.16) | 243 (0.15) | 409 (0.18) |
Palpitations | 8 (0.16) | 216 (2.35) | 816 (3.37) | 1 (0.64) | 573 (2.31) | 3658 (2.27) | 5305 (2.37) |
Pancreatitis | 7 (0.14) | 11 (0.12) | 3 (0.01) | 0 | 36 (0.15) | 35 (0.02) | 93 (0.04) |
Pancreatitis acute | 3 (0.06) | 9 (0.10) | 2 (0.01) | 0 | 23 (0.09) | 13 (0.01) | 51 (0.02) |
Panic attack | 1 (0.02) | 11 (0.12) | 51 (0.21) | 0 | 34 (0.14) | 223 (0.14) | 322 (0.14) |
Papule | 0 | 0 | 8 (0.03) | 1 (0.64) | 3 (0.01) | 61 (0.04) | 73 (0.03) |
Paraesthesia | 17 (0.35) | 258 (2.80) | 1057 (4.36) | 3 (1.91) | 914 (3.69) | 5426 (3.37) | 7739 (3.45) |
Paraesthesia oral | 0 | 19 (0.21) | 58 (0.24) | 0 | 67 (0.27) | 462 (0.29) | 608 (0.27) |
Paralysis | 12 (0.25) | 42 (0.46) | 96 (0.40) | 0 | 111 (0.45) | 197 (0.12) | 490 (0.22) |
Paranasal sinus discomfort | 0 | 1 (0.01) | 8 (0.03) | 0 | 3 (0.01) | 50 (0.03) | 62 (0.03) |
Paresis | 2 (0.04) | 9 (0.10) | 16 (0.07) | 0 | 37 (0.15) | 21 (0.01) | 87 (0.04) |
Parosmia | 0 | 2 (0.02) | 38 (0.16) | 0 | 11 (0.04) | 202 (0.13) | 254 (0.11) |
Partial seizures | 5 (0.10) | 9 (0.10) | 5 (0.02) | 0 | 18 (0.07) | 34 (0.02) | 74 (0.03) |
Pelvic pain | 0 | 4 (0.04) | 37 (0.15) | 0 | 17 (0.07) | 123 (0.08) | 182 (0.08) |
Pelvic venous thrombosis | 2 (0.04) | 14 (0.15) | 3 (0.01) | 0 | 19 (0.08) | 16 (0.01) | 61 (0.03) |
Periarthritis | 0 | 3 (0.03) | 153 (0.63) | 0 | 5 (0.02) | 314 (0.20) | 475 (0.21) |
Pericardial effusion | 4 (0.08) | 19 (0.21) | 8 (0.03) | 0 | 50 (0.20) | 39 (0.02) | 134 (0.06) |
Pericarditis | 2 (0.04) | 40 (0.43) | 39 (0.16) | 0 | 225 (0.91) | 182 (0.11) | 499 (0.22) |
Periorbital swelling | 0 | 2 (0.02) | 16 (0.07) | 0 | 8 (0.03) | 76 (0.05) | 103 (0.05) |
Peripheral artery thrombosis | 9 (0.18) | 37 (0.40) | 6 (0.02) | 0 | 51 (0.21) | 41 (0.03) | 150 (0.07) |
Peripheral coldness | 4 (0.08) | 24 (0.26) | 163 (0.67) | 0 | 43 (0.17) | 850 (0.53) | 1092 (0.49) |
Peripheral ischaemia | 11 (0.23) | 12 (0.13) | 6 (0.02) | 0 | 32 (0.13) | 14 (0.01) | 79 (0.04) |
Peripheral swelling | 24 (0.49) | 162 (1.76) | 615 (2.54) | 2 (1.27) | 256 (1.03) | 3361 (2.09) | 4461 (1.99) |
Petechiae | 11 (0.23) | 54 (0.59) | 33 (0.14) | 0 | 188 (0.76) | 254 (0.16) | 562 (0.25) |
Petit mal epilepsy | 0 | 6 (0.07) | 8 (0.03) | 0 | 6 (0.02) | 34 (0.02) | 55 (0.02) |
Pharyngeal swelling | 2 (0.04) | 39 (0.42) | 38 (0.16) | 0 | 46 (0.19) | 170 (0.11) | 300 (0.13) |
Phlebitis | 0 | 10 (0.11) | 10 (0.04) | 0 | 31 (0.13) | 107 (0.07) | 158 (0.07) |
Photophobia | 6 (0.12) | 26 (0.28) | 216 (0.89) | 0 | 85 (0.34) | 687 (0.43) | 1026 (0.46) |
Photopsia | 1 (0.02) | 11 (0.12) | 36 (0.15) | 0 | 20 (0.08) | 223 (0.14) | 292 (0.13) |
Photosensitivity reaction | 0 | 4 (0.04) | 31 (0.13) | 0 | 14 (0.06) | 100 (0.06) | 150 (0.07) |
Piloerection | 0 | 0 | 8 (0.03) | 0 | 3 (0.01) | 71 (0.04) | 83 (0.04) |
Platelet count decreased | 34 (0.70) | 78 (0.85) | 32 (0.13) | 1 (0.64) | 138 (0.56) | 198 (0.12) | 516 (0.23) |
Pleural effusion | 10 (0.21) | 36 (0.39) | 6 (0.02) | 0 | 53 (0.21) | 19 (0.01) | 138 (0.06) |
Pleurisy | 0 | 2 (0.02) | 8 (0.03) | 0 | 33 (0.13) | 20 (0.01) | 65 (0.03) |
Pleuritic pain | 0 | 19 (0.21) | 6 (0.02) | 0 | 17 (0.07) | 12 (0.01) | 56 (0.02) |
Pneumonia | 103 (2.11) | 102 (1.11) | 32 (0.13) | 0 | 229 (0.92) | 102 (0.06) | 606 (0.27) |
Pneumonia aspiration | 23 (0.47) | 8 (0.09) | 3 (0.01) | 0 | 8 (0.03) | 5 (0.00) | 52 (0.02) |
Pneumonitis | 8 (0.16) | 10 (0.11) | 7 (0.03) | 0 | 25 (0.10) | 26 (0.02) | 78 (0.03) |
Pollakiuria | 2 (0.04) | 11 (0.12) | 32 (0.13) | 0 | 20 (0.08) | 176 (0.11) | 241 (0.11) |
Polymenorrhoea | 0 | 1 (0.01) | 35 (0.14) | 1 (0.64) | 9 (0.04) | 283 (0.18) | 329 (0.15) |
Polymyalgia rheumatica | 0 | 4 (0.04) | 42 (0.17) | 0 | 15 (0.06) | 95 (0.06) | 157 (0.07) |
Polyneuropathy | 2 (0.04) | 8 (0.09) | 12 (0.05) | 0 | 40 (0.16) | 51 (0.03) | 118 (0.05) |
Poor peripheral circulation | 3 (0.06) | 1 (0.01) | 12 (0.05) | 0 | 2 (0.01) | 36 (0.02) | 55 (0.02) |
Poor quality sleep | 0 | 5 (0.05) | 78 (0.32) | 0 | 3 (0.01) | 434 (0.27) | 521 (0.23) |
Portal vein thrombosis | 33 (0.68) | 69 (0.75) | 2 (0.01) | 0 | 102 (0.41) | 32 (0.02) | 259 (0.12) |
Post viral fatigue syndrome | 0 | 0 | 60 (0.25) | 0 | 4 (0.02) | 78 (0.05) | 142 (0.06) |
Postmenopausal haemorrhage | 0 | 0 | 6 (0.02) | 0 | 12 (0.05) | 221 (0.14) | 240 (0.11) |
Premenstrual pain | 0 | 0 | 10 (0.04) | 0 | 0 | 55 (0.03) | 65 (0.03) |
Presyncope | 6 (0.12) | 15 (0.16) | 93 (0.38) | 0 | 84 (0.34) | 440 (0.27) | 647 (0.29) |
Productive cough | 9 (0.18) | 9 (0.10) | 29 (0.12) | 0 | 31 (0.13) | 120 (0.07) | 201 (0.09) |
Pruritus | 5 (0.10) | 116 (1.26) | 461 (1.90) | 0 | 236 (0.95) | 4014 (2.49) | 4853 (2.16) |
Psoriasis | 0 | 7 (0.08) | 41 (0.17) | 0 | 10 (0.04) | 141 (0.09) | 201 (0.09) |
Psychotic disorder | 0 | 6 (0.07) | 7 (0.03) | 0 | 13 (0.05) | 27 (0.02) | 54 (0.02) |
Pulmonary embolism | 330 (6.77) | 1318 (14.31) | 89 (0.37) | 0 | 2088 (8.43) | 990 (0.61) | 4955 (2.21) |
Pulmonary infarction | 4 (0.08) | 28 (0.30) | 1 (0.00) | 0 | 31 (0.13) | 13 (0.01) | 87 (0.04) |
Pulmonary oedema | 21 (0.43) | 24 (0.26) | 2 (0.01) | 0 | 19 (0.08) | 23 (0.01) | 102 (0.05) |
Pulmonary pain | 0 | 18 (0.20) | 44 (0.18) | 0 | 22 (0.09) | 152 (0.09) | 239 (0.11) |
Pulmonary thrombosis | 22 (0.45) | 23 (0.25) | 3 (0.01) | 0 | 62 (0.25) | 25 (0.02) | 143 (0.06) |
Purpura | 5 (0.10) | 13 (0.14) | 11 (0.05) | 0 | 62 (0.25) | 90 (0.06) | 186 (0.08) |
Pyrexia | 356 (7.30) | 824 (8.95) | 7464 (30.79) | 11 (7.01) | 2996 (12.09) | 41388 (25.71) | 53214 (23.73) |
Q fever | 0 | 1 (0.01) | 13 (0.05) | 0 | 2 (0.01) | 82 (0.05) | 99 (0.04) |
Rash | 15 (0.31) | 135 (1.47) | 517 (2.13) | 3 (1.91) | 442 (1.78) | 4099 (2.55) | 5234 (2.33) |
Rash erythematous | 2 (0.04) | 9 (0.10) | 99 (0.41) | 0 | 39 (0.16) | 892 (0.55) | 1041 (0.46) |
Rash macular | 1 (0.02) | 22 (0.24) | 36 (0.15) | 0 | 47 (0.19) | 385 (0.24) | 491 (0.22) |
Rash maculo-papular | 0 | 3 (0.03) | 3 (0.01) | 0 | 5 (0.02) | 51 (0.03) | 65 (0.03) |
Rash papular | 1 (0.02) | 4 (0.04) | 19 (0.08) | 0 | 12 (0.05) | 243 (0.15) | 282 (0.13) |
Rash pruritic | 1 (0.02) | 11 (0.12) | 59 (0.24) | 0 | 45 (0.18) | 906 (0.56) | 1022 (0.46) |
Rash vesicular | 0 | 4 (0.04) | 7 (0.03) | 0 | 12 (0.05) | 49 (0.03) | 73 (0.03) |
Raynaud's phenomenon | 1 (0.02) | 0 | 20 (0.08) | 0 | 7 (0.03) | 98 (0.06) | 126 (0.06) |
Rectal haemorrhage | 6 (0.12) | 14 (0.15) | 11 (0.05) | 0 | 31 (0.13) | 100 (0.06) | 165 (0.07) |
Renal failure | 26 (0.53) | 30 (0.33) | 6 (0.02) | 0 | 28 (0.11) | 25 (0.02) | 125 (0.06) |
Renal pain | 2 (0.04) | 18 (0.20) | 120 (0.49) | 0 | 49 (0.20) | 654 (0.41) | 844 (0.38) |
Respiration abnormal | 6 (0.12) | 7 (0.08) | 9 (0.04) | 0 | 25 (0.10) | 60 (0.04) | 114 (0.05) |
Respiratory arrest | 10 (0.21) | 16 (0.17) | 1 (0.00) | 0 | 11 (0.04) | 13 (0.01) | 55 (0.02) |
Respiratory disorder | 11 (0.23) | 16 (0.17) | 113 (0.47) | 0 | 31 (0.13) | 29 (0.02) | 204 (0.09) |
Respiratory distress | 17 (0.35) | 27 (0.29) | 13 (0.05) | 1 (0.64) | 143 (0.58) | 80 (0.05) | 304 (0.14) |
Respiratory failure | 42 (0.86) | 41 (0.45) | 0 | 0 | 37 (0.15) | 16 (0.01) | 151 (0.07) |
Respiratory rate increased | 5 (0.10) | 7 (0.08) | 6 (0.02) | 0 | 7 (0.03) | 65 (0.04) | 92 (0.04) |
Restless legs syndrome | 0 | 7 (0.08) | 48 (0.20) | 0 | 10 (0.04) | 258 (0.16) | 324 (0.14) |
Restlessness | 5 (0.10) | 6 (0.07) | 50 (0.21) | 0 | 32 (0.13) | 336 (0.21) | 432 (0.19) |
Retching | 4 (0.08) | 6 (0.07) | 33 (0.14) | 0 | 24 (0.10) | 190 (0.12) | 260 (0.12) |
Retinal artery occlusion | 0 | 3 (0.03) | 30 (0.12) | 0 | 19 (0.08) | 31 (0.02) | 86 (0.04) |
Retinal detachment | 0 | 0 | 20 (0.08) | 0 | 38 (0.15) | 33 (0.02) | 92 (0.04) |
Retinal migraine | 0 | 0 | 7 (0.03) | 0 | 2 (0.01) | 67 (0.04) | 76 (0.03) |
Retinal vein occlusion | 0 | 3 (0.03) | 63 (0.26) | 0 | 17 (0.07) | 156 (0.10) | 240 (0.11) |
Retinal vein thrombosis | 1 (0.02) | 0 | 14 (0.06) | 0 | 6 (0.02) | 49 (0.03) | 71 (0.03) |
Rheumatoid arthritis | 1 (0.02) | 3 (0.03) | 77 (0.32) | 0 | 13 (0.05) | 156 (0.10) | 253 (0.11) |
Rhinitis | 11 (0.23) | 7 (0.08) | 8 (0.03) | 0 | 33 (0.13) | 39 (0.02) | 101 (0.05) |
Rhinorrhoea | 7 (0.14) | 8 (0.09) | 136 (0.56) | 0 | 40 (0.16) | 1052 (0.65) | 1248 (0.56) |
Rotator cuff syndrome | 0 | 1 (0.01) | 27 (0.11) | 0 | 3 (0.01) | 73 (0.05) | 106 (0.05) |
SARS-CoV-2 test negative | 1 (0.02) | 3 (0.03) | 13 (0.05) | 0 | 21 (0.08) | 12 (0.01) | 51 (0.02) |
SARS-CoV-2 test positive | 17 (0.35) | 6 (0.07) | 5 (0.02) | 0 | 66 (0.27) | 43 (0.03) | 145 (0.06) |
Salivary hypersecretion | 0 | 6 (0.07) | 13 (0.05) | 0 | 12 (0.05) | 46 (0.03) | 77 (0.03) |
Sciatica | 0 | 3 (0.03) | 63 (0.26) | 0 | 11 (0.04) | 142 (0.09) | 219 (0.10) |
Seasonal allergy | 1 (0.02) | 0 | 11 (0.05) | 0 | 3 (0.01) | 69 (0.04) | 84 (0.04) |
Seizure | 63 (1.29) | 230 (2.50) | 194 (0.80) | 1 (0.64) | 483 (1.95) | 1074 (0.67) | 2109 (0.94) |
Sensation of foreign body | 0 | 7 (0.08) | 8 (0.03) | 0 | 21 (0.08) | 44 (0.03) | 86 (0.04) |
Sensitive skin | 0 | 3 (0.03) | 60 (0.25) | 0 | 5 (0.02) | 403 (0.25) | 473 (0.21) |
Sensory disturbance | 0 | 11 (0.12) | 55 (0.23) | 0 | 135 (0.54) | 107 (0.07) | 316 (0.14) |
Sensory loss | 0 | 23 (0.25) | 70 (0.29) | 0 | 46 (0.19) | 98 (0.06) | 243 (0.11) |
Sepsis | 61 (1.25) | 43 (0.47) | 9 (0.04) | 0 | 47 (0.19) | 43 (0.03) | 231 (0.10) |
Severe acute respiratory syndrome | 22 (0.45) | 1 (0.01) | 0 | 0 | 125 (0.50) | 29 (0.02) | 177 (0.08) |
Shock | 10 (0.21) | 13 (0.14) | 5 (0.02) | 0 | 6 (0.02) | 41 (0.03) | 78 (0.03) |
Shoulder injury related to vaccine administration | 0 | 0 | 47 (0.19) | 0 | 2 (0.01) | 60 (0.04) | 109 (0.05) |
Sinus congestion | 0 | 4 (0.04) | 8 (0.03) | 0 | 4 (0.02) | 63 (0.04) | 79 (0.04) |
Sinus headache | 0 | 2 (0.02) | 79 (0.33) | 0 | 11 (0.04) | 658 (0.41) | 751 (0.33) |
Sinus pain | 0 | 6 (0.07) | 70 (0.29) | 0 | 5 (0.02) | 439 (0.27) | 521 (0.23) |
Sinus tachycardia | 4 (0.08) | 9 (0.10) | 8 (0.03) | 0 | 36 (0.15) | 45 (0.03) | 104 (0.05) |
Sinusitis | 1 (0.02) | 6 (0.07) | 48 (0.20) | 0 | 15 (0.06) | 263 (0.16) | 334 (0.15) |
Skin burning sensation | 0 | 10 (0.11) | 81 (0.33) | 0 | 33 (0.13) | 365 (0.23) | 490 (0.22) |
Skin discolouration | 7 (0.14) | 16 (0.17) | 24 (0.10) | 0 | 26 (0.10) | 121 (0.08) | 198 (0.09) |
Skin disorder | 2 (0.04) | 5 (0.05) | 124 (0.51) | 0 | 20 (0.08) | 37 (0.02) | 188 (0.08) |
Skin erosion | 0 | 0 | 5 (0.02) | 0 | 3 (0.01) | 42 (0.03) | 51 (0.02) |
Skin exfoliation | 0 | 7 (0.08) | 23 (0.09) | 0 | 11 (0.04) | 88 (0.05) | 131 (0.06) |
Skin haemorrhage | 2 (0.04) | 3 (0.03) | 9 (0.04) | 0 | 17 (0.07) | 31 (0.02) | 64 (0.03) |
Skin irritation | 0 | 0 | 9 (0.04) | 0 | 8 (0.03) | 74 (0.05) | 91 (0.04) |
Skin lesion | 1 (0.02) | 7 (0.08) | 5 (0.02) | 0 | 9 (0.04) | 32 (0.02) | 55 (0.02) |
Skin reaction | 0 | 5 (0.05) | 20 (0.08) | 0 | 13 (0.05) | 128 (0.08) | 166 (0.07) |
Skin sensitisation | 0 | 0 | 16 (0.07) | 0 | 0 | 69 (0.04) | 85 (0.04) |
Skin swelling | 0 | 0 | 5 (0.02) | 0 | 6 (0.02) | 46 (0.03) | 58 (0.03) |
Skin temperature | 0 | 0 | 10 (0.04) | 0 | 0 | 135 (0.08) | 145 (0.06) |
Skin warm | 0 | 4 (0.04) | 30 (0.12) | 0 | 9 (0.04) | 304 (0.19) | 347 (0.15) |
Sleep disorder | 3 (0.06) | 10 (0.11) | 109 (0.45) | 0 | 22 (0.09) | 309 (0.19) | 457 (0.20) |
Sneezing | 1 (0.02) | 7 (0.08) | 32 (0.13) | 0 | 10 (0.04) | 314 (0.20) | 364 (0.16) |
Somnolence | 28 (0.57) | 93 (1.01) | 239 (0.99) | 1 (0.64) | 219 (0.88) | 1412 (0.88) | 2020 (0.90) |
Speech disorder | 11 (0.23) | 26 (0.28) | 52 (0.21) | 0 | 81 (0.33) | 86 (0.05) | 279 (0.12) |
Spinal pain | 1 (0.02) | 9 (0.10) | 50 (0.21) | 0 | 21 (0.08) | 178 (0.11) | 265 (0.12) |
Splenic infarction | 7 (0.14) | 9 (0.10) | 1 (0.00) | 0 | 23 (0.09) | 12 (0.01) | 58 (0.03) |
Splenic vein thrombosis | 9 (0.18) | 16 (0.17) | 3 (0.01) | 0 | 11 (0.04) | 8 (0.00) | 53 (0.02) |
Stomatitis | 0 | 0 | 10 (0.04) | 0 | 5 (0.02) | 57 (0.04) | 72 (0.03) |
Stress | 0 | 2 (0.02) | 34 (0.14) | 0 | 5 (0.02) | 84 (0.05) | 126 (0.06) |
Subarachnoid haemorrhage | 52 (1.07) | 71 (0.77) | 3 (0.01) | 0 | 49 (0.20) | 20 (0.01) | 209 (0.09) |
Subdural haematoma | 7 (0.14) | 19 (0.21) | 2 (0.01) | 0 | 16 (0.06) | 12 (0.01) | 62 (0.03) |
Sudden death | 202 (4.14) | 0 | 0 | 0 | 0 | 0 | 203 (0.09) |
Sudden hearing loss | 0 | 1 (0.01) | 43 (0.18) | 0 | 20 (0.08) | 103 (0.06) | 169 (0.08) |
Suicidal ideation | 1 (0.02) | 17 (0.18) | 16 (0.07) | 0 | 5 (0.02) | 93 (0.06) | 138 (0.06) |
Superficial vein thrombosis | 1 (0.02) | 30 (0.33) | 14 (0.06) | 0 | 86 (0.35) | 275 (0.17) | 416 (0.19) |
Superior sagittal sinus thrombosis | 16 (0.33) | 25 (0.27) | 3 (0.01) | 0 | 24 (0.10) | 11 (0.01) | 85 (0.04) |
Supraventricular tachycardia | 0 | 5 (0.05) | 9 (0.04) | 0 | 28 (0.11) | 23 (0.01) | 66 (0.03) |
Suspected COVID-19 | 2 (0.04) | 2 (0.02) | 5 (0.02) | 0 | 13 (0.05) | 38 (0.02) | 60 (0.03) |
Sweating fever | 0 | 2 (0.02) | 77 (0.32) | 0 | 7 (0.03) | 536 (0.33) | 622 (0.28) |
Swelling | 3 (0.06) | 60 (0.65) | 206 (0.85) | 1 (0.64) | 116 (0.47) | 1408 (0.87) | 1800 (0.80) |
Swelling face | 1 (0.02) | 36 (0.39) | 82 (0.34) | 0 | 117 (0.47) | 664 (0.41) | 908 (0.40) |
Swelling of eyelid | 0 | 3 (0.03) | 8 (0.03) | 0 | 13 (0.05) | 65 (0.04) | 89 (0.04) |
Swollen tongue | 1 (0.02) | 61 (0.66) | 43 (0.18) | 0 | 63 (0.25) | 343 (0.21) | 514 (0.23) |
Syncope | 53 (1.09) | 237 (2.57) | 267 (1.10) | 3 (1.91) | 574 (2.32) | 2114 (1.31) | 3304 (1.47) |
Systemic lupus erythematosus | 0 | 6 (0.07) | 8 (0.03) | 0 | 8 (0.03) | 31 (0.02) | 53 (0.02) |
Tachycardia | 30 (0.62) | 230 (2.50) | 297 (1.23) | 0 | 553 (2.23) | 1210 (0.75) | 2367 (1.06) |
Tachypnoea | 10 (0.21) | 9 (0.10) | 10 (0.04) | 0 | 17 (0.07) | 22 (0.01) | 70 (0.03) |
Taste disorder | 0 | 6 (0.07) | 61 (0.25) | 0 | 28 (0.11) | 308 (0.19) | 406 (0.18) |
Tearfulness | 0 | 1 (0.01) | 18 (0.07) | 0 | 0 | 70 (0.04) | 89 (0.04) |
Temperature intolerance | 0 | 0 | 9 (0.04) | 0 | 2 (0.01) | 65 (0.04) | 76 (0.03) |
Tenderness | 4 (0.08) | 6 (0.07) | 94 (0.39) | 0 | 52 (0.21) | 1076 (0.67) | 1250 (0.56) |
Tendonitis | 0 | 1 (0.01) | 41 (0.17) | 0 | 0 | 65 (0.04) | 108 (0.05) |
Tension | 1 (0.02) | 4 (0.04) | 5 (0.02) | 0 | 2 (0.01) | 40 (0.02) | 54 (0.02) |
Tension headache | 1 (0.02) | 10 (0.11) | 146 (0.60) | 0 | 56 (0.23) | 988 (0.61) | 1202 (0.54) |
Testicular pain | 0 | 0 | 8 (0.03) | 0 | 3 (0.01) | 61 (0.04) | 72 (0.03) |
Therapeutic response unexpected | 0 | 0 | 10 (0.04) | 0 | 3 (0.01) | 57 (0.04) | 71 (0.03) |
Thirst | 1 (0.02) | 18 (0.20) | 121 (0.50) | 1 (0.64) | 22 (0.09) | 900 (0.56) | 1065 (0.47) |
Throat irritation | 1 (0.02) | 14 (0.15) | 21 (0.09) | 0 | 35 (0.14) | 140 (0.09) | 212 (0.09) |
Throat tightness | 0 | 29 (0.31) | 26 (0.11) | 0 | 44 (0.18) | 142 (0.09) | 242 (0.11) |
Thrombocytopenia | 262 (5.37) | 591 (6.42) | 61 (0.25) | 0 | 1038 (4.19) | 753 (0.47) | 2989 (1.33) |
Thrombophlebitis | 4 (0.08) | 42 (0.46) | 28 (0.12) | 0 | 48 (0.19) | 248 (0.15) | 377 (0.17) |
Thrombosis | 200 (4.10) | 575 (6.24) | 201 (0.83) | 1 (0.64) | 736 (2.97) | 1286 (0.80) | 3117 (1.39) |
Thrombosis in device | 2 (0.04) | 24 (0.26) | 1 (0.00) | 0 | 17 (0.07) | 17 (0.01) | 62 (0.03) |
Thrombosis with thrombocytopenia syndrome | 23 (0.47) | 17 (0.18) | 0 | 0 | 38 (0.15) | 21 (0.01) | 121 (0.05) |
Thunderclap headache | 1 (0.02) | 2 (0.02) | 9 (0.04) | 0 | 18 (0.07) | 30 (0.02) | 60 (0.03) |
Tinnitus | 1 (0.02) | 41 (0.45) | 647 (2.67) | 1 (0.64) | 161 (0.65) | 2301 (1.43) | 3163 (1.41) |
Tongue oedema | 2 (0.04) | 12 (0.13) | 3 (0.01) | 0 | 20 (0.08) | 39 (0.02) | 79 (0.04) |
Tonsillitis | 0 | 2 (0.02) | 9 (0.04) | 0 | 6 (0.02) | 57 (0.04) | 74 (0.03) |
Toothache | 1 (0.02) | 2 (0.02) | 36 (0.15) | 0 | 10 (0.04) | 224 (0.14) | 273 (0.12) |
Transient ischaemic attack | 7 (0.14) | 135 (1.47) | 57 (0.24) | 0 | 350 (1.41) | 353 (0.22) | 910 (0.41) |
Tremor | 20 (0.41) | 123 (1.34) | 1080 (4.45) | 1 (0.64) | 353 (1.42) | 7243 (4.50) | 8839 (3.94) |
Trigeminal neuralgia | 0 | 1 (0.01) | 39 (0.16) | 0 | 27 (0.11) | 100 (0.06) | 168 (0.07) |
Troponin increased | 4 (0.08) | 9 (0.10) | 3 (0.01) | 0 | 37 (0.15) | 12 (0.01) | 93 (0.04) |
Unresponsive to stimuli | 27 (0.55) | 18 (0.20) | 7 (0.03) | 0 | 28 (0.11) | 63 (0.04) | 158 (0.07) |
Urinary incontinence | 4 (0.08) | 10 (0.11) | 35 (0.14) | 0 | 32 (0.13) | 74 (0.05) | 162 (0.07) |
Urinary retention | 2 (0.04) | 14 (0.15) | 27 (0.11) | 0 | 32 (0.13) | 53 (0.03) | 136 (0.06) |
Urinary tract infection | 11 (0.23) | 12 (0.13) | 26 (0.11) | 0 | 47 (0.19) | 176 (0.11) | 287 (0.13) |
Urticaria | 1 (0.02) | 95 (1.03) | 149 (0.61) | 0 | 172 (0.69) | 1415 (0.88) | 1834 (0.82) |
Uterine haemorrhage | 0 | 2 (0.02) | 3 (0.01) | 0 | 8 (0.03) | 43 (0.03) | 57 (0.03) |
Uveitis | 0 | 0 | 12 (0.05) | 0 | 7 (0.03) | 35 (0.02) | 54 (0.02) |
Vaccination complication | 2 (0.04) | 2 (0.02) | 17 (0.07) | 0 | 9 (0.04) | 83 (0.05) | 115 (0.05) |
Vaccination failure | 100 (2.05) | 53 (0.58) | 1 (0.00) | 0 | 342 (1.38) | 9932 (6.17) | 10437 (4.65) |
Vaccination site bruising | 0 | 2 (0.02) | 15 (0.06) | 0 | 4 (0.02) | 76 (0.05) | 98 (0.04) |
Vaccination site erythema | 1 (0.02) | 7 (0.08) | 78 (0.32) | 0 | 30 (0.12) | 400 (0.25) | 516 (0.23) |
Vaccination site induration | 0 | 0 | 13 (0.05) | 0 | 2 (0.01) | 55 (0.03) | 70 (0.03) |
Vaccination site inflammation | 0 | 2 (0.02) | 8 (0.03) | 0 | 7 (0.03) | 59 (0.04) | 76 (0.03) |
Vaccination site mass | 0 | 2 (0.02) | 33 (0.14) | 0 | 7 (0.03) | 266 (0.17) | 310 (0.14) |
Vaccination site movement impairment | 0 | 2 (0.02) | 56 (0.23) | 0 | 18 (0.07) | 74 (0.05) | 150 (0.07) |
Vaccination site oedema | 0 | 2 (0.02) | 25 (0.10) | 0 | 3 (0.01) | 49 (0.03) | 79 (0.04) |
Vaccination site pain | 12 (0.25) | 23 (0.25) | 404 (1.67) | 0 | 142 (0.57) | 1825 (1.13) | 2416 (1.08) |
Vaccination site pruritus | 0 | 1 (0.01) | 24 (0.10) | 0 | 10 (0.04) | 89 (0.06) | 124 (0.06) |
Vaccination site rash | 1 (0.02) | 0 | 9 (0.04) | 0 | 4 (0.02) | 100 (0.06) | 114 (0.05) |
Vaccination site reaction | 1 (0.02) | 2 (0.02) | 32 (0.13) | 0 | 19 (0.08) | 94 (0.06) | 150 (0.07) |
Vaccination site swelling | 0 | 4 (0.04) | 89 (0.37) | 0 | 32 (0.13) | 312 (0.19) | 439 (0.20) |
Vaccination site warmth | 0 | 1 (0.01) | 41 (0.17) | 0 | 5 (0.02) | 229 (0.14) | 277 (0.12) |
Vaginal discharge | 0 | 1 (0.01) | 6 (0.02) | 0 | 5 (0.02) | 43 (0.03) | 55 (0.02) |
Vaginal haemorrhage | 0 | 20 (0.22) | 51 (0.21) | 6 (3.82) | 59 (0.24) | 673 (0.42) | 812 (0.36) |
Varicose vein | 0 | 10 (0.11) | 12 (0.05) | 0 | 9 (0.04) | 97 (0.06) | 129 (0.06) |
Vascular headache | 0 | 4 (0.04) | 21 (0.09) | 0 | 3 (0.01) | 50 (0.03) | 79 (0.04) |
Vascular pain | 0 | 7 (0.08) | 15 (0.06) | 0 | 9 (0.04) | 106 (0.07) | 138 (0.06) |
Vasculitis | 9 (0.18) | 29 (0.31) | 18 (0.07) | 0 | 42 (0.17) | 103 (0.06) | 210 (0.09) |
Vasodilatation | 0 | 5 (0.05) | 18 (0.07) | 1 (0.64) | 10 (0.04) | 88 (0.05) | 123 (0.05) |
Venous thrombosis | 8 (0.16) | 68 (0.74) | 19 (0.08) | 0 | 88 (0.36) | 118 (0.07) | 311 (0.14) |
Venous thrombosis limb | 5 (0.10) | 41 (0.45) | 10 (0.04) | 0 | 66 (0.27) | 129 (0.08) | 253 (0.11) |
Vertigo | 4 (0.08) | 60 (0.65) | 509 (2.10) | 0 | 288 (1.16) | 1596 (0.99) | 2479 (1.11) |
Vertigo positional | 0 | 1 (0.01) | 27 (0.11) | 0 | 27 (0.11) | 98 (0.06) | 154 (0.07) |
Vestibular neuronitis | 0 | 1 (0.01) | 20 (0.08) | 0 | 38 (0.15) | 30 (0.02) | 89 (0.04) |
Viral infection | 3 (0.06) | 3 (0.03) | 23 (0.09) | 0 | 14 (0.06) | 40 (0.02) | 85 (0.04) |
Vision blurred | 11 (0.23) | 97 (1.05) | 530 (2.19) | 0 | 304 (1.23) | 1952 (1.21) | 2924 (1.30) |
Visual acuity reduced | 0 | 3 (0.03) | 22 (0.09) | 0 | 11 (0.04) | 47 (0.03) | 85 (0.04) |
Visual field defect | 1 (0.02) | 5 (0.05) | 18 (0.07) | 0 | 21 (0.08) | 41 (0.03) | 88 (0.04) |
Visual impairment | 10 (0.21) | 48 (0.52) | 258 (1.06) | 0 | 225 (0.91) | 568 (0.35) | 1139 (0.51) |
Vitreous detachment | 0 | 0 | 9 (0.04) | 0 | 3 (0.01) | 60 (0.04) | 73 (0.03) |
Vitreous floaters | 1 (0.02) | 0 | 33 (0.14) | 0 | 12 (0.05) | 133 (0.08) | 179 (0.08) |
Vomiting | 185 (3.79) | 292 (3.17) | 1413 (5.83) | 0 | 1045 (4.22) | 8310 (5.16) | 11336 (5.05) |
Vomiting projectile | 2 (0.04) | 2 (0.02) | 33 (0.14) | 0 | 8 (0.03) | 96 (0.06) | 141 (0.06) |
Weight decreased | 4 (0.08) | 13 (0.14) | 75 (0.31) | 0 | 54 (0.22) | 150 (0.09) | 302 (0.13) |
Weight increased | 0 | 3 (0.03) | 15 (0.06) | 0 | 7 (0.03) | 43 (0.03) | 68 (0.03) |
Wheezing | 4 (0.08) | 42 (0.46) | 69 (0.28) | 0 | 44 (0.18) | 387 (0.24) | 556 (0.25) |
Withdrawal syndrome | 0 | 1 (0.01) | 5 (0.02) | 0 | 2 (0.01) | 56 (0.03) | 64 (0.03) |
Yawning | 0 | 1 (0.01) | 7 (0.03) | 0 | 0 | 45 (0.03) | 54 (0.02) |