Eudravigilance C-19 - Janssen
Liste des effets indésirables (uniquement ceux qui apparaissent dans plus de 50 cas graves)
PT |
Décès 886 (%) |
Mise en jeu du pronostic vital 1317 (%) |
Invalidité ou incapacité 1057 (%) |
Anomalies congénitales 6 (%) |
Hospitalisation 3224 (%) |
Médicalement significatif 7114 (%) |
Cas Graves 13604 (%) |
|---|---|---|---|---|---|---|---|
| Abdominal discomfort | 3 (0.34) | 2 (0.15) | 7 (0.66) | 0 | 15 (0.47) | 27 (0.38) | 54 (0.40) |
| Abdominal pain | 18 (2.03) | 35 (2.66) | 23 (2.18) | 0 | 58 (1.80) | 64 (0.90) | 198 (1.46) |
| Abdominal pain upper | 7 (0.79) | 11 (0.84) | 10 (0.95) | 0 | 46 (1.43) | 68 (0.96) | 142 (1.04) |
| Acute kidney injury | 15 (1.69) | 9 (0.68) | 0 | 0 | 23 (0.71) | 2 (0.03) | 51 (0.37) |
| Acute myocardial infarction | 14 (1.58) | 32 (2.43) | 2 (0.19) | 0 | 33 (1.02) | 4 (0.06) | 86 (0.63) |
| Acute respiratory failure | 15 (1.69) | 21 (1.59) | 0 | 0 | 15 (0.47) | 0 | 51 (0.37) |
| Adverse event | 1 (0.11) | 2 (0.15) | 2 (0.19) | 0 | 79 (2.45) | 42 (0.59) | 126 (0.93) |
| Ageusia | 8 (0.90) | 0 | 5 (0.47) | 0 | 15 (0.47) | 24 (0.34) | 54 (0.40) |
| Amnesia | 1 (0.11) | 4 (0.30) | 3 (0.28) | 0 | 18 (0.56) | 27 (0.38) | 53 (0.39) |
| Anaphylactic reaction | 4 (0.45) | 24 (1.82) | 1 (0.09) | 0 | 17 (0.53) | 71 (1.00) | 118 (0.87) |
| Angiogram | 1 (0.11) | 26 (1.97) | 5 (0.47) | 0 | 14 (0.43) | 14 (0.20) | 60 (0.44) |
| Angiogram cerebral abnormal | 4 (0.45) | 27 (2.05) | 6 (0.57) | 0 | 23 (0.71) | 1 (0.01) | 61 (0.45) |
| Angiogram pulmonary abnormal | 6 (0.68) | 60 (4.56) | 1 (0.09) | 0 | 54 (1.67) | 2 (0.03) | 123 (0.90) |
| Anticoagulant therapy | 15 (1.69) | 119 (9.04) | 10 (0.95) | 0 | 89 (2.76) | 12 (0.17) | 245 (1.80) |
| Anxiety | 1 (0.11) | 7 (0.53) | 5 (0.47) | 0 | 33 (1.02) | 57 (0.80) | 103 (0.76) |
| Aphasia | 7 (0.79) | 17 (1.29) | 13 (1.23) | 0 | 27 (0.84) | 10 (0.14) | 74 (0.54) |
| Arrhythmia | 6 (0.68) | 4 (0.30) | 3 (0.28) | 0 | 20 (0.62) | 30 (0.42) | 63 (0.46) |
| Arthralgia | 9 (1.02) | 31 (2.35) | 204 (19.30) | 0 | 89 (2.76) | 227 (3.19) | 560 (4.12) |
| Asthenia | 57 (6.43) | 50 (3.80) | 69 (6.53) | 0 | 170 (5.27) | 224 (3.15) | 577 (4.24) |
| Atrial fibrillation | 8 (0.90) | 19 (1.44) | 2 (0.19) | 0 | 33 (1.02) | 20 (0.28) | 82 (0.60) |
| Back pain | 16 (1.81) | 31 (2.35) | 41 (3.88) | 0 | 76 (2.36) | 104 (1.46) | 269 (1.98) |
| Balance disorder | 1 (0.11) | 7 (0.53) | 27 (2.55) | 0 | 40 (1.24) | 35 (0.49) | 110 (0.81) |
| Bell's palsy | 0 | 6 (0.46) | 12 (1.14) | 0 | 21 (0.65) | 35 (0.49) | 74 (0.54) |
| Blood pressure increased | 3 (0.34) | 17 (1.29) | 4 (0.38) | 0 | 33 (1.02) | 335 (4.71) | 393 (2.89) |
| Blood test | 3 (0.34) | 85 (6.45) | 33 (3.12) | 0 | 56 (1.74) | 82 (1.15) | 259 (1.90) |
| Burning sensation | 0 | 12 (0.91) | 15 (1.42) | 0 | 12 (0.37) | 53 (0.75) | 92 (0.68) |
| COVID-19 | 80 (9.03) | 31 (2.35) | 3 (0.28) | 0 | 146 (4.53) | 1768 (24.85) | 2029 (14.91) |
| COVID-19 pneumonia | 37 (4.18) | 29 (2.20) | 3 (0.28) | 0 | 60 (1.86) | 7 (0.10) | 137 (1.01) |
| Cardiac arrest | 45 (5.08) | 21 (1.59) | 0 | 0 | 6 (0.19) | 2 (0.03) | 74 (0.54) |
| Cellulitis | 1 (0.11) | 1 (0.08) | 0 | 0 | 7 (0.22) | 102 (1.43) | 111 (0.82) |
| Cerebral haemorrhage | 27 (3.05) | 24 (1.82) | 3 (0.28) | 0 | 26 (0.81) | 3 (0.04) | 84 (0.62) |
| Cerebral infarction | 7 (0.79) | 15 (1.14) | 9 (0.85) | 0 | 32 (0.99) | 4 (0.06) | 67 (0.49) |
| Cerebral thrombosis | 5 (0.56) | 16 (1.21) | 4 (0.38) | 0 | 23 (0.71) | 11 (0.15) | 59 (0.43) |
| Cerebral venous sinus thrombosis | 21 (2.37) | 28 (2.13) | 2 (0.19) | 0 | 44 (1.36) | 6 (0.08) | 103 (0.76) |
| Cerebrovascular accident | 42 (4.74) | 118 (8.96) | 51 (4.82) | 1 (16.67) | 168 (5.21) | 71 (1.00) | 451 (3.32) |
| Chest X-ray | 3 (0.34) | 26 (1.97) | 7 (0.66) | 0 | 19 (0.59) | 27 (0.38) | 82 (0.60) |
| Chest X-ray abnormal | 6 (0.68) | 19 (1.44) | 2 (0.19) | 0 | 21 (0.65) | 4 (0.06) | 52 (0.38) |
| Chest discomfort | 5 (0.56) | 23 (1.75) | 18 (1.70) | 1 (16.67) | 61 (1.89) | 71 (1.00) | 179 (1.32) |
| Chest pain | 25 (2.82) | 116 (8.81) | 26 (2.46) | 0 | 192 (5.96) | 176 (2.47) | 539 (3.96) |
| Chills | 28 (3.16) | 66 (5.01) | 313 (29.61) | 0 | 179 (5.55) | 301 (4.23) | 888 (6.53) |
| Computerised tomogram | 8 (0.90) | 75 (5.69) | 21 (1.99) | 0 | 64 (1.99) | 60 (0.84) | 228 (1.68) |
| Computerised tomogram abnormal | 4 (0.45) | 23 (1.75) | 2 (0.19) | 0 | 19 (0.59) | 21 (0.30) | 69 (0.51) |
| Computerised tomogram head | 1 (0.11) | 22 (1.67) | 5 (0.47) | 0 | 24 (0.74) | 17 (0.24) | 69 (0.51) |
| Computerised tomogram head abnormal | 18 (2.03) | 43 (3.26) | 12 (1.14) | 0 | 50 (1.55) | 2 (0.03) | 125 (0.92) |
| Computerised tomogram head normal | 2 (0.23) | 12 (0.91) | 12 (1.14) | 0 | 23 (0.71) | 3 (0.04) | 52 (0.38) |
| Computerised tomogram thorax | 2 (0.23) | 21 (1.59) | 1 (0.09) | 0 | 22 (0.68) | 24 (0.34) | 70 (0.51) |
| Computerised tomogram thorax abnormal | 8 (0.90) | 94 (7.14) | 5 (0.47) | 0 | 45 (1.40) | 5 (0.07) | 157 (1.15) |
| Condition aggravated | 21 (2.37) | 28 (2.13) | 26 (2.46) | 1 (16.67) | 49 (1.52) | 78 (1.10) | 205 (1.51) |
| Confusional state | 6 (0.68) | 18 (1.37) | 7 (0.66) | 0 | 38 (1.18) | 39 (0.55) | 110 (0.81) |
| Contusion | 1 (0.11) | 27 (2.05) | 6 (0.57) | 0 | 38 (1.18) | 69 (0.97) | 141 (1.04) |
| Cough | 87 (9.82) | 27 (2.05) | 15 (1.42) | 0 | 131 (4.06) | 99 (1.39) | 360 (2.65) |
| Death | 283 (31.94) | 1 (0.08) | 0 | 0 | 0 | 0 | 284 (2.09) |
| Decreased appetite | 32 (3.61) | 10 (0.76) | 22 (2.08) | 0 | 55 (1.71) | 68 (0.96) | 187 (1.37) |
| Deep vein thrombosis | 19 (2.14) | 147 (11.16) | 10 (0.95) | 0 | 168 (5.21) | 263 (3.70) | 609 (4.48) |
| Diarrhoea | 20 (2.26) | 21 (1.59) | 24 (2.27) | 0 | 82 (2.54) | 121 (1.70) | 268 (1.97) |
| Discomfort | 3 (0.34) | 5 (0.38) | 6 (0.57) | 0 | 12 (0.37) | 42 (0.59) | 69 (0.51) |
| Disturbance in attention | 0 | 2 (0.15) | 5 (0.47) | 0 | 18 (0.56) | 31 (0.44) | 57 (0.42) |
| Dizziness | 29 (3.27) | 91 (6.91) | 83 (7.85) | 0 | 284 (8.81) | 402 (5.65) | 892 (6.56) |
| Drug ineffective | 3 (0.34) | 6 (0.46) | 0 | 0 | 7 (0.22) | 60 (0.84) | 76 (0.56) |
| Dysarthria | 7 (0.79) | 21 (1.59) | 10 (0.95) | 0 | 47 (1.46) | 14 (0.20) | 99 (0.73) |
| Dysphagia | 5 (0.56) | 8 (0.61) | 10 (0.95) | 0 | 25 (0.78) | 14 (0.20) | 63 (0.46) |
| Dyspnoea | 135 (15.24) | 179 (13.59) | 40 (3.78) | 1 (16.67) | 330 (10.24) | 248 (3.49) | 944 (6.94) |
| Dysstasia | 3 (0.34) | 11 (0.84) | 10 (0.95) | 0 | 20 (0.62) | 16 (0.22) | 60 (0.44) |
| Echocardiogram | 5 (0.56) | 57 (4.33) | 4 (0.38) | 0 | 47 (1.46) | 10 (0.14) | 123 (0.90) |
| Electrocardiogram | 2 (0.23) | 59 (4.48) | 7 (0.66) | 0 | 32 (0.99) | 54 (0.76) | 154 (1.13) |
| Electrocardiogram abnormal | 3 (0.34) | 17 (1.29) | 4 (0.38) | 0 | 24 (0.74) | 10 (0.14) | 58 (0.43) |
| Endotracheal intubation | 31 (3.50) | 18 (1.37) | 0 | 0 | 13 (0.40) | 0 | 62 (0.46) |
| Epistaxis | 2 (0.23) | 6 (0.46) | 1 (0.09) | 1 (16.67) | 19 (0.59) | 43 (0.60) | 73 (0.54) |
| Erythema | 4 (0.45) | 12 (0.91) | 2 (0.19) | 0 | 25 (0.78) | 62 (0.87) | 106 (0.78) |
| Eye pain | 0 | 10 (0.76) | 10 (0.95) | 0 | 17 (0.53) | 31 (0.44) | 69 (0.51) |
| Facial paralysis | 2 (0.23) | 22 (1.67) | 16 (1.51) | 0 | 85 (2.64) | 56 (0.79) | 181 (1.33) |
| Fall | 12 (1.35) | 21 (1.59) | 5 (0.47) | 0 | 65 (2.02) | 53 (0.75) | 156 (1.15) |
| Fatigue | 41 (4.63) | 90 (6.83) | 384 (36.33) | 0 | 231 (7.17) | 476 (6.69) | 1230 (9.04) |
| Feeling abnormal | 8 (0.90) | 25 (1.90) | 20 (1.89) | 0 | 76 (2.36) | 178 (2.50) | 307 (2.26) |
| Feeling cold | 2 (0.23) | 3 (0.23) | 10 (0.95) | 1 (16.67) | 9 (0.28) | 38 (0.53) | 63 (0.46) |
| Feeling hot | 1 (0.11) | 3 (0.23) | 8 (0.76) | 0 | 28 (0.87) | 66 (0.93) | 106 (0.78) |
| Fibrin D dimer | 0 | 17 (1.29) | 3 (0.28) | 0 | 20 (0.62) | 24 (0.34) | 64 (0.47) |
| Fibrin D dimer increased | 5 (0.56) | 39 (2.96) | 2 (0.19) | 0 | 49 (1.52) | 33 (0.46) | 129 (0.95) |
| Full blood count | 2 (0.23) | 43 (3.26) | 8 (0.76) | 0 | 30 (0.93) | 44 (0.62) | 127 (0.93) |
| Gait disturbance | 3 (0.34) | 28 (2.13) | 36 (3.41) | 0 | 74 (2.30) | 71 (1.00) | 214 (1.57) |
| Gait inability | 8 (0.90) | 11 (0.84) | 15 (1.42) | 0 | 41 (1.27) | 25 (0.35) | 100 (0.74) |
| Guillain-Barre syndrome | 5 (0.56) | 56 (4.25) | 44 (4.16) | 0 | 196 (6.08) | 72 (1.01) | 373 (2.74) |
| Haemoglobin decreased | 6 (0.68) | 11 (0.84) | 1 (0.09) | 1 (16.67) | 29 (0.90) | 10 (0.14) | 58 (0.43) |
| Hallucination | 0 | 2 (0.15) | 1 (0.09) | 0 | 14 (0.43) | 42 (0.59) | 60 (0.44) |
| Head discomfort | 0 | 3 (0.23) | 6 (0.57) | 0 | 11 (0.34) | 31 (0.44) | 51 (0.37) |
| Headache | 62 (7.00) | 155 (11.77) | 456 (43.14) | 0 | 489 (15.17) | 738 (10.37) | 1906 (14.01) |
| Heart rate increased | 4 (0.45) | 21 (1.59) | 15 (1.42) | 0 | 44 (1.36) | 65 (0.91) | 154 (1.13) |
| Heavy menstrual bleeding | 0 | 7 (0.53) | 9 (0.85) | 0 | 7 (0.22) | 61 (0.86) | 84 (0.62) |
| Hemiparesis | 7 (0.79) | 25 (1.90) | 15 (1.42) | 0 | 52 (1.61) | 33 (0.46) | 133 (0.98) |
| Hemiplegia | 7 (0.79) | 7 (0.53) | 10 (0.95) | 0 | 13 (0.40) | 15 (0.21) | 52 (0.38) |
| Herpes zoster | 0 | 2 (0.15) | 4 (0.38) | 0 | 13 (0.40) | 48 (0.67) | 67 (0.49) |
| Hyperhidrosis | 7 (0.79) | 20 (1.52) | 37 (3.50) | 0 | 58 (1.80) | 158 (2.22) | 281 (2.07) |
| Hypersensitivity | 0 | 11 (0.84) | 8 (0.76) | 0 | 25 (0.78) | 55 (0.77) | 99 (0.73) |
| Hypertension | 14 (1.58) | 29 (2.20) | 13 (1.23) | 1 (16.67) | 90 (2.79) | 128 (1.80) | 275 (2.02) |
| Hypoaesthesia | 4 (0.45) | 57 (4.33) | 71 (6.72) | 0 | 178 (5.52) | 208 (2.92) | 521 (3.83) |
| Hypotension | 15 (1.69) | 17 (1.29) | 3 (0.28) | 0 | 47 (1.46) | 65 (0.91) | 151 (1.11) |
| Hypoxia | 16 (1.81) | 14 (1.06) | 1 (0.09) | 0 | 20 (0.62) | 5 (0.07) | 56 (0.41) |
| Illness | 5 (0.56) | 6 (0.46) | 5 (0.47) | 0 | 24 (0.74) | 39 (0.55) | 80 (0.59) |
| Immune thrombocytopenia | 8 (0.90) | 22 (1.67) | 0 | 0 | 43 (1.33) | 14 (0.20) | 87 (0.64) |
| Immunoglobulin therapy | 2 (0.23) | 24 (1.82) | 16 (1.51) | 0 | 43 (1.33) | 1 (0.01) | 86 (0.63) |
| Impaired work ability | 1 (0.11) | 14 (1.06) | 19 (1.80) | 0 | 21 (0.65) | 34 (0.48) | 91 (0.67) |
| Incorrect route of product administration | 0 | 1 (0.08) | 1 (0.09) | 0 | 23 (0.71) | 26 (0.37) | 51 (0.37) |
| Inflammation | 0 | 5 (0.38) | 9 (0.85) | 0 | 15 (0.47) | 28 (0.39) | 57 (0.42) |
| Influenza like illness | 8 (0.90) | 8 (0.61) | 35 (3.31) | 0 | 47 (1.46) | 82 (1.15) | 182 (1.34) |
| Injection site erythema | 0 | 3 (0.23) | 2 (0.19) | 0 | 11 (0.34) | 40 (0.56) | 56 (0.41) |
| Injection site pain | 2 (0.23) | 11 (0.84) | 20 (1.89) | 0 | 59 (1.83) | 157 (2.21) | 249 (1.83) |
| Injection site reaction | 0 | 1 (0.08) | 115 (10.88) | 0 | 3 (0.09) | 9 (0.13) | 128 (0.94) |
| Injection site swelling | 0 | 1 (0.08) | 3 (0.28) | 0 | 15 (0.47) | 40 (0.56) | 59 (0.43) |
| Insomnia | 3 (0.34) | 10 (0.76) | 17 (1.61) | 0 | 41 (1.27) | 85 (1.19) | 156 (1.15) |
| Intensive care | 22 (2.48) | 45 (3.42) | 6 (0.57) | 0 | 32 (0.99) | 0 | 105 (0.77) |
| Ischaemic stroke | 3 (0.34) | 23 (1.75) | 9 (0.85) | 0 | 29 (0.90) | 9 (0.13) | 73 (0.54) |
| Joint swelling | 0 | 8 (0.61) | 4 (0.38) | 0 | 15 (0.47) | 42 (0.59) | 69 (0.51) |
| Laboratory test | 7 (0.79) | 52 (3.95) | 16 (1.51) | 0 | 30 (0.93) | 42 (0.59) | 147 (1.08) |
| Lethargy | 3 (0.34) | 5 (0.38) | 4 (0.38) | 0 | 10 (0.31) | 30 (0.42) | 52 (0.38) |
| Limb discomfort | 4 (0.45) | 11 (0.84) | 18 (1.70) | 0 | 39 (1.21) | 46 (0.65) | 118 (0.87) |
| Loss of consciousness | 27 (3.05) | 29 (2.20) | 9 (0.85) | 0 | 63 (1.95) | 186 (2.61) | 316 (2.32) |
| Loss of personal independence in daily activities | 1 (0.11) | 7 (0.53) | 20 (1.89) | 0 | 17 (0.53) | 36 (0.51) | 85 (0.62) |
| Lumbar puncture | 0 | 13 (0.99) | 23 (2.18) | 0 | 26 (0.81) | 5 (0.07) | 67 (0.49) |
| Lymphadenopathy | 0 | 7 (0.53) | 13 (1.23) | 0 | 29 (0.90) | 39 (0.55) | 88 (0.65) |
| Magnetic resonance imaging | 1 (0.11) | 40 (3.04) | 22 (2.08) | 0 | 39 (1.21) | 34 (0.48) | 136 (1.00) |
| Magnetic resonance imaging head | 0 | 15 (1.14) | 12 (1.14) | 0 | 20 (0.62) | 13 (0.18) | 60 (0.44) |
| Magnetic resonance imaging head abnormal | 3 (0.34) | 44 (3.34) | 33 (3.12) | 0 | 71 (2.20) | 3 (0.04) | 154 (1.13) |
| Malaise | 60 (6.77) | 55 (4.18) | 225 (21.29) | 0 | 173 (5.37) | 212 (2.98) | 727 (5.34) |
| Metabolic function test | 3 (0.34) | 23 (1.75) | 5 (0.47) | 0 | 15 (0.47) | 26 (0.37) | 72 (0.53) |
| Migraine | 2 (0.23) | 16 (1.21) | 23 (2.18) | 0 | 27 (0.84) | 60 (0.84) | 130 (0.96) |
| Mobility decreased | 3 (0.34) | 16 (1.21) | 21 (1.99) | 0 | 26 (0.81) | 41 (0.58) | 107 (0.79) |
| Muscle spasms | 4 (0.45) | 13 (0.99) | 19 (1.80) | 0 | 43 (1.33) | 110 (1.55) | 190 (1.40) |
| Muscular weakness | 5 (0.56) | 27 (2.05) | 42 (3.97) | 0 | 83 (2.57) | 74 (1.04) | 233 (1.71) |
| Musculoskeletal stiffness | 1 (0.11) | 3 (0.23) | 15 (1.42) | 0 | 15 (0.47) | 40 (0.56) | 74 (0.54) |
| Myalgia | 14 (1.58) | 32 (2.43) | 333 (31.50) | 0 | 185 (5.74) | 259 (3.64) | 823 (6.05) |
| Myocardial infarction | 47 (5.30) | 48 (3.64) | 2 (0.19) | 0 | 59 (1.83) | 27 (0.38) | 183 (1.35) |
| Myocarditis | 12 (1.35) | 22 (1.67) | 2 (0.19) | 0 | 62 (1.92) | 25 (0.35) | 125 (0.92) |
| Nasopharyngitis | 10 (1.13) | 4 (0.30) | 4 (0.38) | 0 | 26 (0.81) | 47 (0.66) | 91 (0.67) |
| Nausea | 29 (3.27) | 68 (5.16) | 221 (20.91) | 0 | 180 (5.58) | 342 (4.81) | 846 (6.22) |
| Neck pain | 1 (0.11) | 16 (1.21) | 22 (2.08) | 0 | 37 (1.15) | 61 (0.86) | 137 (1.01) |
| Neuralgia | 0 | 8 (0.61) | 12 (1.14) | 0 | 17 (0.53) | 38 (0.53) | 75 (0.55) |
| Neuropathy peripheral | 0 | 2 (0.15) | 21 (1.99) | 0 | 14 (0.43) | 91 (1.28) | 128 (0.94) |
| Oedema peripheral | 1 (0.11) | 8 (0.61) | 6 (0.57) | 0 | 24 (0.74) | 36 (0.51) | 75 (0.55) |
| Oropharyngeal pain | 4 (0.45) | 8 (0.61) | 8 (0.76) | 0 | 31 (0.96) | 31 (0.44) | 82 (0.60) |
| Oxygen saturation decreased | 11 (1.24) | 10 (0.76) | 0 | 0 | 25 (0.78) | 20 (0.28) | 66 (0.49) |
| Pain | 24 (2.71) | 48 (3.64) | 92 (8.70) | 2 (33.33) | 168 (5.21) | 377 (5.30) | 714 (5.25) |
| Pain in extremity | 11 (1.24) | 101 (7.67) | 85 (8.04) | 1 (16.67) | 204 (6.33) | 502 (7.06) | 906 (6.66) |
| Pallor | 2 (0.23) | 7 (0.53) | 5 (0.47) | 0 | 16 (0.50) | 38 (0.53) | 69 (0.51) |
| Palpitations | 2 (0.23) | 16 (1.21) | 19 (1.80) | 0 | 49 (1.52) | 64 (0.90) | 152 (1.12) |
| Paraesthesia | 4 (0.45) | 30 (2.28) | 58 (5.49) | 0 | 171 (5.30) | 235 (3.30) | 500 (3.68) |
| Paralysis | 2 (0.23) | 12 (0.91) | 8 (0.76) | 0 | 27 (0.84) | 60 (0.84) | 110 (0.81) |
| Pericarditis | 2 (0.23) | 15 (1.14) | 3 (0.28) | 0 | 43 (1.33) | 51 (0.72) | 114 (0.84) |
| Peripheral swelling | 5 (0.56) | 50 (3.80) | 16 (1.51) | 0 | 86 (2.67) | 171 (2.40) | 329 (2.42) |
| Petechiae | 1 (0.11) | 17 (1.29) | 1 (0.09) | 0 | 37 (1.15) | 19 (0.27) | 75 (0.55) |
| Platelet count decreased | 13 (1.47) | 72 (5.47) | 3 (0.28) | 1 (16.67) | 92 (2.85) | 51 (0.72) | 232 (1.71) |
| Platelet count normal | 3 (0.34) | 19 (1.44) | 4 (0.38) | 0 | 31 (0.96) | 20 (0.28) | 77 (0.57) |
| Pneumonia | 19 (2.14) | 29 (2.20) | 3 (0.28) | 0 | 56 (1.74) | 21 (0.30) | 129 (0.95) |
| Presyncope | 0 | 6 (0.46) | 6 (0.57) | 0 | 22 (0.68) | 54 (0.76) | 88 (0.65) |
| Pruritus | 0 | 5 (0.38) | 6 (0.57) | 0 | 19 (0.59) | 51 (0.72) | 81 (0.60) |
| Pulmonary embolism | 51 (5.76) | 281 (21.34) | 5 (0.47) | 0 | 310 (9.62) | 86 (1.21) | 733 (5.39) |
| Pulmonary thrombosis | 5 (0.56) | 54 (4.10) | 2 (0.19) | 0 | 59 (1.83) | 12 (0.17) | 132 (0.97) |
| Pyrexia | 122 (13.77) | 108 (8.20) | 441 (41.72) | 1 (16.67) | 361 (11.20) | 586 (8.24) | 1628 (11.97) |
| Rash | 1 (0.11) | 12 (0.91) | 15 (1.42) | 0 | 57 (1.77) | 112 (1.57) | 198 (1.46) |
| SARS-CoV-2 test negative | 4 (0.45) | 12 (0.91) | 8 (0.76) | 0 | 24 (0.74) | 11 (0.15) | 59 (0.43) |
| SARS-CoV-2 test positive | 25 (2.82) | 18 (1.37) | 1 (0.09) | 0 | 48 (1.49) | 34 (0.48) | 126 (0.93) |
| Seizure | 14 (1.58) | 25 (1.90) | 4 (0.38) | 0 | 61 (1.89) | 116 (1.63) | 220 (1.62) |
| Sensory disturbance | 0 | 3 (0.23) | 9 (0.85) | 0 | 21 (0.65) | 41 (0.58) | 74 (0.54) |
| Skin discolouration | 1 (0.11) | 8 (0.61) | 3 (0.28) | 0 | 12 (0.37) | 34 (0.48) | 58 (0.43) |
| Sleep disorder | 1 (0.11) | 2 (0.15) | 10 (0.95) | 0 | 14 (0.43) | 25 (0.35) | 52 (0.38) |
| Somnolence | 3 (0.34) | 7 (0.53) | 7 (0.66) | 0 | 22 (0.68) | 43 (0.60) | 82 (0.60) |
| Speech disorder | 1 (0.11) | 15 (1.14) | 12 (1.14) | 0 | 34 (1.05) | 29 (0.41) | 92 (0.68) |
| Suspected COVID-19 | 37 (4.18) | 6 (0.46) | 0 | 0 | 41 (1.27) | 272 (3.82) | 356 (2.62) |
| Swelling | 2 (0.23) | 4 (0.30) | 7 (0.66) | 0 | 23 (0.71) | 49 (0.69) | 85 (0.62) |
| Syncope | 11 (1.24) | 42 (3.19) | 19 (1.80) | 0 | 95 (2.95) | 371 (5.22) | 539 (3.96) |
| Tachycardia | 2 (0.23) | 24 (1.82) | 8 (0.76) | 0 | 56 (1.74) | 37 (0.52) | 128 (0.94) |
| Therapy non-responder | 1 (0.11) | 0 | 2 (0.19) | 0 | 7 (0.22) | 406 (5.71) | 416 (3.06) |
| Thrombocytopenia | 35 (3.95) | 71 (5.39) | 3 (0.28) | 0 | 107 (3.32) | 38 (0.53) | 255 (1.87) |
| Thrombosis | 68 (7.67) | 158 (12.00) | 28 (2.65) | 1 (16.67) | 206 (6.39) | 502 (7.06) | 964 (7.09) |
| Tinnitus | 2 (0.23) | 4 (0.30) | 24 (2.27) | 0 | 28 (0.87) | 72 (1.01) | 130 (0.96) |
| Transient ischaemic attack | 2 (0.23) | 15 (1.14) | 5 (0.47) | 0 | 37 (1.15) | 35 (0.49) | 94 (0.69) |
| Tremor | 4 (0.45) | 11 (0.84) | 23 (2.18) | 0 | 46 (1.43) | 88 (1.24) | 174 (1.28) |
| Troponin increased | 7 (0.79) | 17 (1.29) | 1 (0.09) | 0 | 31 (0.96) | 0 | 56 (0.41) |
| Ultrasound Doppler | 1 (0.11) | 20 (1.52) | 6 (0.57) | 0 | 29 (0.90) | 61 (0.86) | 117 (0.86) |
| Ultrasound Doppler abnormal | 4 (0.45) | 81 (6.15) | 10 (0.95) | 0 | 48 (1.49) | 51 (0.72) | 194 (1.43) |
| Ultrasound scan | 0 | 27 (2.05) | 5 (0.47) | 0 | 25 (0.78) | 88 (1.24) | 145 (1.07) |
| Ultrasound scan abnormal | 2 (0.23) | 15 (1.14) | 4 (0.38) | 0 | 12 (0.37) | 74 (1.04) | 107 (0.79) |
| Unresponsive to stimuli | 18 (2.03) | 13 (0.99) | 0 | 0 | 8 (0.25) | 10 (0.14) | 51 (0.37) |
| Urticaria | 0 | 3 (0.23) | 8 (0.76) | 0 | 11 (0.34) | 45 (0.63) | 67 (0.49) |
| Vaccination failure | 98 (11.06) | 41 (3.11) | 2 (0.19) | 0 | 181 (5.61) | 2075 (29.17) | 2401 (17.65) |
| Vaccination site pain | 7 (0.79) | 2 (0.15) | 24 (2.27) | 0 | 4 (0.12) | 32 (0.45) | 69 (0.51) |
| Vertigo | 2 (0.23) | 14 (1.06) | 17 (1.61) | 0 | 32 (0.99) | 52 (0.73) | 117 (0.86) |
| Vision blurred | 1 (0.11) | 16 (1.21) | 23 (2.18) | 0 | 49 (1.52) | 92 (1.29) | 182 (1.34) |
| Visual impairment | 2 (0.23) | 12 (0.91) | 21 (1.99) | 0 | 40 (1.24) | 59 (0.83) | 135 (0.99) |
| Vomiting | 35 (3.95) | 50 (3.80) | 53 (5.01) | 0 | 120 (3.72) | 168 (2.36) | 430 (3.16) |
| Weight decreased | 4 (0.45) | 5 (0.38) | 5 (0.47) | 0 | 27 (0.84) | 38 (0.53) | 81 (0.60) |
| X-ray | 2 (0.23) | 21 (1.59) | 7 (0.66) | 0 | 13 (0.40) | 13 (0.18) | 56 (0.41) |