Eudravigilance C-19 - Janssen

Liste des effets indésirables (uniquement ceux qui apparaissent dans plus de 50 cas graves)

PT

Décès

1157 (%)

Mise en jeu du pronostic vital

1508 (%)

Invalidité ou incapacité

1234 (%)

Anomalies congénitales

8 (%)

Hospitalisation

3768 (%)

Médicalement significatif

11195 (%)

Cas Graves

18870 (%)

Abdominal discomfort 4 (0.35) 2 (0.13) 9 (0.73) 0 15 (0.40) 33 (0.29) 64 (0.34)
Abdominal pain 19 (1.64) 38 (2.52) 26 (2.11) 0 70 (1.86) 72 (0.64) 225 (1.19)
Abdominal pain upper 7 (0.61) 13 (0.86) 11 (0.89) 0 57 (1.51) 78 (0.70) 166 (0.88)
Acute kidney injury 20 (1.73) 10 (0.66) 0 0 33 (0.88) 3 (0.03) 68 (0.36)
Acute myocardial infarction 19 (1.64) 37 (2.45) 2 (0.16) 0 46 (1.22) 5 (0.04) 111 (0.59)
Acute respiratory failure 20 (1.73) 24 (1.59) 0 0 24 (0.64) 0 68 (0.36)
Adverse event 2 (0.17) 2 (0.13) 2 (0.16) 0 85 (2.26) 49 (0.44) 140 (0.74)
Ageusia 8 (0.69) 0 6 (0.49) 0 18 (0.48) 33 (0.29) 67 (0.36)
Amnesia 2 (0.17) 5 (0.33) 4 (0.32) 0 20 (0.53) 31 (0.28) 62 (0.33)
Anaphylactic reaction 4 (0.35) 27 (1.79) 1 (0.08) 0 21 (0.56) 74 (0.66) 128 (0.68)
Anaphylactic shock 2 (0.17) 16 (1.06) 0 0 13 (0.35) 20 (0.18) 51 (0.27)
Angina pectoris 1 (0.09) 4 (0.27) 3 (0.24) 0 13 (0.35) 45 (0.40) 67 (0.36)
Angiogram 1 (0.09) 30 (1.99) 8 (0.65) 0 19 (0.50) 18 (0.16) 76 (0.40)
Angiogram cerebral abnormal 7 (0.61) 27 (1.79) 7 (0.57) 0 26 (0.69) 1 (0.01) 68 (0.36)
Angiogram pulmonary abnormal 6 (0.52) 62 (4.11) 1 (0.08) 0 57 (1.51) 3 (0.03) 129 (0.68)
Anticoagulant therapy 19 (1.64) 145 (9.62) 12 (0.97) 0 109 (2.89) 17 (0.15) 302 (1.60)
Anxiety 1 (0.09) 11 (0.73) 8 (0.65) 0 42 (1.11) 67 (0.60) 129 (0.68)
Aphasia 8 (0.69) 18 (1.19) 13 (1.05) 0 33 (0.88) 14 (0.13) 86 (0.46)
Arrhythmia 7 (0.61) 5 (0.33) 3 (0.24) 0 25 (0.66) 47 (0.42) 87 (0.46)
Arthralgia 9 (0.78) 36 (2.39) 237 (19.21) 0 110 (2.92) 275 (2.46) 668 (3.54)
Asthenia 65 (5.62) 60 (3.98) 75 (6.08) 0 207 (5.49) 267 (2.38) 681 (3.61)
Atrial fibrillation 11 (0.95) 23 (1.53) 2 (0.16) 0 43 (1.14) 28 (0.25) 107 (0.57)
Autoimmune disorder 1 (0.09) 1 (0.07) 11 (0.89) 0 3 (0.08) 42 (0.38) 58 (0.31)
Back pain 19 (1.64) 38 (2.52) 46 (3.73) 0 91 (2.42) 134 (1.20) 331 (1.75)
Balance disorder 1 (0.09) 11 (0.73) 32 (2.59) 0 41 (1.09) 48 (0.43) 133 (0.70)
Bell's palsy 0 6 (0.40) 15 (1.22) 0 27 (0.72) 40 (0.36) 88 (0.47)
Blood glucose increased 7 (0.61) 12 (0.80) 5 (0.41) 0 20 (0.53) 15 (0.13) 60 (0.32)
Blood pressure decreased 8 (0.69) 10 (0.66) 3 (0.24) 0 9 (0.24) 22 (0.20) 53 (0.28)
Blood pressure increased 5 (0.43) 21 (1.39) 5 (0.41) 0 41 (1.09) 354 (3.16) 427 (2.26)
Blood test 3 (0.26) 102 (6.76) 36 (2.92) 0 66 (1.75) 96 (0.86) 303 (1.61)
Blood test abnormal 1 (0.09) 16 (1.06) 11 (0.89) 0 12 (0.32) 18 (0.16) 58 (0.31)
Burning sensation 1 (0.09) 15 (0.99) 18 (1.46) 0 15 (0.40) 62 (0.55) 111 (0.59)
COVID-19 119 (10.29) 36 (2.39) 3 (0.24) 0 228 (6.05) 4730 (42.25) 5116 (27.11)
COVID-19 pneumonia 50 (4.32) 32 (2.12) 3 (0.24) 0 88 (2.34) 10 (0.09) 184 (0.98)
Cardiac arrest 57 (4.93) 24 (1.59) 0 0 7 (0.19) 2 (0.02) 90 (0.48)
Cellulitis 1 (0.09) 2 (0.13) 0 0 8 (0.21) 103 (0.92) 114 (0.60)
Cerebral haemorrhage 37 (3.20) 24 (1.59) 4 (0.32) 0 27 (0.72) 3 (0.03) 96 (0.51)
Cerebral infarction 9 (0.78) 16 (1.06) 12 (0.97) 0 35 (0.93) 7 (0.06) 79 (0.42)
Cerebral thrombosis 5 (0.43) 22 (1.46) 4 (0.32) 0 25 (0.66) 13 (0.12) 70 (0.37)
Cerebral venous sinus thrombosis 22 (1.90) 30 (1.99) 2 (0.16) 0 47 (1.25) 7 (0.06) 110 (0.58)
Cerebrovascular accident 56 (4.84) 137 (9.08) 58 (4.70) 1 (12.50) 191 (5.07) 95 (0.85) 538 (2.85)
Chest X-ray 3 (0.26) 28 (1.86) 7 (0.57) 0 22 (0.58) 30 (0.27) 90 (0.48)
Chest X-ray abnormal 9 (0.78) 20 (1.33) 2 (0.16) 0 34 (0.90) 6 (0.05) 71 (0.38)
Chest discomfort 5 (0.43) 27 (1.79) 20 (1.62) 1 (12.50) 65 (1.73) 96 (0.86) 215 (1.14)
Chest pain 30 (2.59) 133 (8.82) 38 (3.08) 0 229 (6.08) 228 (2.04) 663 (3.51)
Chills 30 (2.59) 74 (4.91) 333 (26.99) 0 201 (5.33) 350 (3.13) 990 (5.25)
Circulatory collapse 3 (0.26) 3 (0.20) 0 0 9 (0.24) 38 (0.34) 53 (0.28)
Computerised tomogram 8 (0.69) 89 (5.90) 25 (2.03) 0 75 (1.99) 70 (0.63) 267 (1.41)
Computerised tomogram abnormal 5 (0.43) 26 (1.72) 2 (0.16) 0 20 (0.53) 22 (0.20) 75 (0.40)
Computerised tomogram head 1 (0.09) 26 (1.72) 8 (0.65) 0 26 (0.69) 20 (0.18) 81 (0.43)
Computerised tomogram head abnormal 21 (1.82) 46 (3.05) 12 (0.97) 0 54 (1.43) 3 (0.03) 136 (0.72)
Computerised tomogram head normal 3 (0.26) 12 (0.80) 13 (1.05) 0 26 (0.69) 4 (0.04) 58 (0.31)
Computerised tomogram thorax 2 (0.17) 25 (1.66) 1 (0.08) 0 23 (0.61) 25 (0.22) 76 (0.40)
Computerised tomogram thorax abnormal 9 (0.78) 101 (6.70) 5 (0.41) 0 52 (1.38) 6 (0.05) 173 (0.92)
Condition aggravated 27 (2.33) 30 (1.99) 29 (2.35) 1 (12.50) 66 (1.75) 95 (0.85) 251 (1.33)
Confusional state 7 (0.61) 18 (1.19) 8 (0.65) 1 (12.50) 45 (1.19) 43 (0.38) 125 (0.66)
Contusion 1 (0.09) 29 (1.92) 8 (0.65) 0 41 (1.09) 77 (0.69) 156 (0.83)
Cough 104 (8.99) 28 (1.86) 16 (1.30) 0 158 (4.19) 115 (1.03) 423 (2.24)
Death 411 (35.52) 1 (0.07) 0 0 0 0 412 (2.18)
Decreased appetite 39 (3.37) 11 (0.73) 24 (1.94) 0 61 (1.62) 79 (0.71) 215 (1.14)
Deep vein thrombosis 23 (1.99) 168 (11.14) 12 (0.97) 0 189 (5.02) 294 (2.63) 688 (3.65)
Dehydration 3 (0.26) 2 (0.13) 4 (0.32) 0 23 (0.61) 24 (0.21) 56 (0.30)
Diarrhoea 23 (1.99) 24 (1.59) 26 (2.11) 0 96 (2.55) 136 (1.21) 305 (1.62)
Discomfort 3 (0.26) 6 (0.40) 8 (0.65) 0 15 (0.40) 52 (0.46) 85 (0.45)
Disturbance in attention 0 3 (0.20) 6 (0.49) 0 23 (0.61) 42 (0.38) 75 (0.40)
Dizziness 33 (2.85) 108 (7.16) 92 (7.46) 0 314 (8.33) 460 (4.11) 1013 (5.37)
Drug ineffective 4 (0.35) 6 (0.40) 0 0 8 (0.21) 70 (0.63) 88 (0.47)
Dysarthria 9 (0.78) 22 (1.46) 10 (0.81) 0 52 (1.38) 17 (0.15) 110 (0.58)
Dysphagia 7 (0.61) 8 (0.53) 11 (0.89) 0 26 (0.69) 20 (0.18) 74 (0.39)
Dyspnoea 157 (13.57) 202 (13.40) 47 (3.81) 1 (12.50) 389 (10.32) 312 (2.79) 1127 (5.97)
Dyspnoea exertional 1 (0.09) 19 (1.26) 6 (0.49) 0 16 (0.42) 20 (0.18) 63 (0.33)
Dysstasia 3 (0.26) 11 (0.73) 11 (0.89) 0 24 (0.64) 21 (0.19) 70 (0.37)
Echocardiogram 5 (0.43) 68 (4.51) 4 (0.32) 0 56 (1.49) 15 (0.13) 148 (0.78)
Electrocardiogram 3 (0.26) 64 (4.24) 9 (0.73) 0 37 (0.98) 60 (0.54) 173 (0.92)
Electrocardiogram abnormal 3 (0.26) 23 (1.53) 5 (0.41) 0 31 (0.82) 15 (0.13) 77 (0.41)
Electrocardiogram normal 1 (0.09) 16 (1.06) 1 (0.08) 0 20 (0.53) 15 (0.13) 53 (0.28)
Endotracheal intubation 34 (2.94) 20 (1.33) 0 0 17 (0.45) 0 71 (0.38)
Epistaxis 2 (0.17) 7 (0.46) 1 (0.08) 1 (12.50) 19 (0.50) 50 (0.45) 82 (0.43)
Erythema 4 (0.35) 15 (0.99) 4 (0.32) 0 29 (0.77) 68 (0.61) 121 (0.64)
Eye pain 0 10 (0.66) 11 (0.89) 0 17 (0.45) 36 (0.32) 75 (0.40)
Facial paralysis 3 (0.26) 23 (1.53) 19 (1.54) 0 99 (2.63) 66 (0.59) 210 (1.11)
Facial paresis 0 4 (0.27) 9 (0.73) 0 29 (0.77) 9 (0.08) 51 (0.27)
Fall 14 (1.21) 23 (1.53) 9 (0.73) 0 79 (2.10) 61 (0.54) 186 (0.99)
Fatigue 51 (4.41) 105 (6.96) 419 (33.95) 0 263 (6.98) 558 (4.98) 1405 (7.45)
Feeling abnormal 11 (0.95) 27 (1.79) 27 (2.19) 0 86 (2.28) 219 (1.96) 370 (1.96)
Feeling cold 2 (0.17) 4 (0.27) 11 (0.89) 1 (12.50) 9 (0.24) 44 (0.39) 71 (0.38)
Feeling hot 1 (0.09) 3 (0.20) 10 (0.81) 0 33 (0.88) 72 (0.64) 119 (0.63)
Fibrin D dimer 1 (0.09) 21 (1.39) 3 (0.24) 0 24 (0.64) 28 (0.25) 77 (0.41)
Fibrin D dimer increased 6 (0.52) 42 (2.79) 3 (0.24) 0 51 (1.35) 37 (0.33) 140 (0.74)
Full blood count 2 (0.17) 45 (2.98) 9 (0.73) 0 32 (0.85) 47 (0.42) 135 (0.72)
Gait disturbance 5 (0.43) 29 (1.92) 43 (3.48) 0 87 (2.31) 84 (0.75) 250 (1.32)
Gait inability 8 (0.69) 15 (0.99) 15 (1.22) 0 45 (1.19) 30 (0.27) 113 (0.60)
Guillain-Barre syndrome 6 (0.52) 64 (4.24) 55 (4.46) 0 217 (5.76) 92 (0.82) 434 (2.30)
Haemoglobin decreased 7 (0.61) 11 (0.73) 1 (0.08) 1 (12.50) 33 (0.88) 10 (0.09) 63 (0.33)
Haemorrhage 7 (0.61) 8 (0.53) 0 0 11 (0.29) 27 (0.24) 53 (0.28)
Hallucination 0 2 (0.13) 1 (0.08) 0 15 (0.40) 46 (0.41) 65 (0.34)
Head discomfort 0 3 (0.20) 7 (0.57) 0 14 (0.37) 40 (0.36) 64 (0.34)
Headache 69 (5.96) 176 (11.67) 501 (40.60) 0 541 (14.36) 836 (7.47) 2131 (11.29)
Heart rate increased 4 (0.35) 23 (1.53) 18 (1.46) 0 48 (1.27) 85 (0.76) 183 (0.97)
Heavy menstrual bleeding 0 7 (0.46) 12 (0.97) 0 8 (0.21) 78 (0.70) 105 (0.56)
Hemiparesis 9 (0.78) 27 (1.79) 15 (1.22) 0 58 (1.54) 38 (0.34) 149 (0.79)
Hemiplegia 7 (0.61) 10 (0.66) 12 (0.97) 0 13 (0.35) 19 (0.17) 61 (0.32)
Herpes zoster 0 2 (0.13) 7 (0.57) 0 19 (0.50) 57 (0.51) 85 (0.45)
Hyperhidrosis 8 (0.69) 24 (1.59) 40 (3.24) 0 62 (1.65) 179 (1.60) 314 (1.66)
Hypersensitivity 0 12 (0.80) 9 (0.73) 0 28 (0.74) 64 (0.57) 113 (0.60)
Hypersomnia 1 (0.09) 3 (0.20) 6 (0.49) 0 9 (0.24) 33 (0.29) 52 (0.28)
Hypertension 15 (1.30) 33 (2.19) 15 (1.22) 1 (12.50) 100 (2.65) 139 (1.24) 303 (1.61)
Hypoaesthesia 5 (0.43) 66 (4.38) 88 (7.13) 0 191 (5.07) 249 (2.22) 603 (3.20)
Hypotension 16 (1.38) 17 (1.13) 4 (0.32) 0 53 (1.41) 69 (0.62) 163 (0.86)
Hypoxia 19 (1.64) 16 (1.06) 1 (0.08) 0 26 (0.69) 5 (0.04) 67 (0.36)
Illness 5 (0.43) 6 (0.40) 7 (0.57) 0 26 (0.69) 53 (0.47) 98 (0.52)
Immune thrombocytopenia 6 (0.52) 23 (1.53) 0 0 43 (1.14) 14 (0.13) 86 (0.46)
Immunoglobulin therapy 2 (0.17) 27 (1.79) 17 (1.38) 0 47 (1.25) 1 (0.01) 94 (0.50)
Impaired work ability 1 (0.09) 16 (1.06) 26 (2.11) 0 32 (0.85) 48 (0.43) 125 (0.66)
Incorrect route of product administration 0 2 (0.13) 1 (0.08) 0 23 (0.61) 26 (0.23) 52 (0.28)
Inflammation 0 7 (0.46) 13 (1.05) 0 17 (0.45) 32 (0.29) 70 (0.37)
Influenza like illness 8 (0.69) 8 (0.53) 39 (3.16) 0 51 (1.35) 94 (0.84) 202 (1.07)
Injection site erythema 0 3 (0.20) 4 (0.32) 0 13 (0.35) 41 (0.37) 61 (0.32)
Injection site pain 2 (0.17) 11 (0.73) 26 (2.11) 0 64 (1.70) 176 (1.57) 279 (1.48)
Injection site reaction 0 3 (0.20) 131 (10.62) 0 3 (0.08) 13 (0.12) 150 (0.79)
Injection site swelling 0 1 (0.07) 5 (0.41) 0 16 (0.42) 45 (0.40) 67 (0.36)
Insomnia 3 (0.26) 10 (0.66) 25 (2.03) 0 45 (1.19) 114 (1.02) 197 (1.04)
Intensive care 26 (2.25) 57 (3.78) 6 (0.49) 0 36 (0.96) 0 125 (0.66)
Ischaemic stroke 4 (0.35) 33 (2.19) 11 (0.89) 0 34 (0.90) 10 (0.09) 92 (0.49)
Joint swelling 0 10 (0.66) 4 (0.32) 0 15 (0.40) 46 (0.41) 75 (0.40)
Laboratory test 7 (0.61) 60 (3.98) 19 (1.54) 0 34 (0.90) 46 (0.41) 166 (0.88)
Lethargy 4 (0.35) 6 (0.40) 4 (0.32) 0 11 (0.29) 32 (0.29) 57 (0.30)
Limb discomfort 4 (0.35) 11 (0.73) 20 (1.62) 0 42 (1.11) 53 (0.47) 130 (0.69)
Loss of consciousness 29 (2.51) 30 (1.99) 10 (0.81) 0 69 (1.83) 217 (1.94) 359 (1.90)
Loss of personal independence in daily activities 1 (0.09) 8 (0.53) 24 (1.94) 1 (12.50) 21 (0.56) 47 (0.42) 106 (0.56)
Lumbar puncture 0 13 (0.86) 23 (1.86) 0 29 (0.77) 5 (0.04) 70 (0.37)
Lymphadenopathy 0 7 (0.46) 17 (1.38) 0 32 (0.85) 47 (0.42) 103 (0.55)
Magnetic resonance imaging 2 (0.17) 46 (3.05) 28 (2.27) 0 47 (1.25) 39 (0.35) 162 (0.86)
Magnetic resonance imaging abnormal 0 22 (1.46) 8 (0.65) 0 16 (0.42) 10 (0.09) 56 (0.30)
Magnetic resonance imaging head 0 16 (1.06) 16 (1.30) 0 23 (0.61) 16 (0.14) 71 (0.38)
Magnetic resonance imaging head abnormal 4 (0.35) 47 (3.12) 36 (2.92) 0 77 (2.04) 6 (0.05) 170 (0.90)
Malaise 68 (5.88) 63 (4.18) 245 (19.85) 0 186 (4.94) 243 (2.17) 808 (4.28)
Memory impairment 1 (0.09) 7 (0.46) 6 (0.49) 0 16 (0.42) 21 (0.19) 51 (0.27)
Metabolic function test 3 (0.26) 24 (1.59) 5 (0.41) 0 18 (0.48) 30 (0.27) 80 (0.42)
Migraine 2 (0.17) 17 (1.13) 27 (2.19) 0 35 (0.93) 84 (0.75) 167 (0.89)
Mobility decreased 5 (0.43) 17 (1.13) 24 (1.94) 0 28 (0.74) 53 (0.47) 127 (0.67)
Monoplegia 0 3 (0.20) 8 (0.65) 0 6 (0.16) 34 (0.30) 51 (0.27)
Movement disorder 1 (0.09) 3 (0.20) 12 (0.97) 0 15 (0.40) 25 (0.22) 56 (0.30)
Muscle spasms 5 (0.43) 16 (1.06) 21 (1.70) 0 51 (1.35) 133 (1.19) 228 (1.21)
Muscular weakness 8 (0.69) 33 (2.19) 58 (4.70) 0 98 (2.60) 91 (0.81) 292 (1.55)
Musculoskeletal stiffness 1 (0.09) 4 (0.27) 18 (1.46) 0 17 (0.45) 49 (0.44) 89 (0.47)
Myalgia 14 (1.21) 37 (2.45) 366 (29.66) 0 199 (5.28) 293 (2.62) 909 (4.82)
Myocardial infarction 72 (6.22) 56 (3.71) 4 (0.32) 0 70 (1.86) 40 (0.36) 242 (1.28)
Myocarditis 12 (1.04) 31 (2.06) 3 (0.24) 0 79 (2.10) 49 (0.44) 176 (0.93)
Nasopharyngitis 10 (0.86) 5 (0.33) 5 (0.41) 0 27 (0.72) 54 (0.48) 101 (0.54)
Nausea 29 (2.51) 75 (4.97) 234 (18.96) 0 204 (5.41) 384 (3.43) 932 (4.94)
Neck pain 1 (0.09) 17 (1.13) 28 (2.27) 0 42 (1.11) 71 (0.63) 159 (0.84)
Neuralgia 0 9 (0.60) 18 (1.46) 0 21 (0.56) 53 (0.47) 101 (0.54)
Neurological symptom 2 (0.17) 9 (0.60) 7 (0.57) 0 20 (0.53) 15 (0.13) 54 (0.29)
Neuropathy peripheral 0 2 (0.13) 20 (1.62) 0 16 (0.42) 109 (0.97) 147 (0.78)
Oedema peripheral 1 (0.09) 8 (0.53) 6 (0.49) 0 30 (0.80) 40 (0.36) 86 (0.46)
Off label use 5 (0.43) 1 (0.07) 1 (0.08) 0 20 (0.53) 52 (0.46) 79 (0.42)
Oropharyngeal pain 5 (0.43) 9 (0.60) 8 (0.65) 0 37 (0.98) 40 (0.36) 99 (0.52)
Oxygen saturation decreased 16 (1.38) 10 (0.66) 0 0 28 (0.74) 23 (0.21) 77 (0.41)
Pain 25 (2.16) 58 (3.85) 105 (8.51) 2 (25.00) 184 (4.88) 463 (4.14) 841 (4.46)
Pain in extremity 13 (1.12) 112 (7.43) 107 (8.67) 1 (12.50) 231 (6.13) 585 (5.23) 1054 (5.59)
Pallor 2 (0.17) 9 (0.60) 5 (0.41) 0 17 (0.45) 43 (0.38) 77 (0.41)
Palpitations 3 (0.26) 19 (1.26) 24 (1.94) 0 54 (1.43) 81 (0.72) 184 (0.98)
Paraesthesia 5 (0.43) 36 (2.39) 74 (6.00) 0 195 (5.18) 284 (2.54) 596 (3.16)
Paralysis 2 (0.17) 13 (0.86) 10 (0.81) 1 (12.50) 34 (0.90) 70 (0.63) 131 (0.69)
Pericarditis 2 (0.17) 16 (1.06) 3 (0.24) 0 52 (1.38) 65 (0.58) 138 (0.73)
Peripheral swelling 5 (0.43) 60 (3.98) 19 (1.54) 0 91 (2.42) 191 (1.71) 367 (1.94)
Petechiae 1 (0.09) 17 (1.13) 1 (0.08) 0 37 (0.98) 27 (0.24) 83 (0.44)
Platelet count decreased 18 (1.56) 73 (4.84) 3 (0.24) 1 (12.50) 96 (2.55) 54 (0.48) 245 (1.30)
Platelet count normal 3 (0.26) 19 (1.26) 5 (0.41) 0 31 (0.82) 23 (0.21) 81 (0.43)
Pneumonia 22 (1.90) 32 (2.12) 4 (0.32) 0 68 (1.80) 27 (0.24) 154 (0.82)
Presyncope 0 6 (0.40) 7 (0.57) 0 22 (0.58) 56 (0.50) 91 (0.48)
Pruritus 0 8 (0.53) 8 (0.65) 0 21 (0.56) 56 (0.50) 93 (0.49)
Pulmonary embolism 72 (6.22) 312 (20.69) 8 (0.65) 0 349 (9.26) 93 (0.83) 834 (4.42)
Pulmonary thrombosis 8 (0.69) 66 (4.38) 2 (0.16) 0 63 (1.67) 22 (0.20) 161 (0.85)
Pyrexia 135 (11.67) 122 (8.09) 469 (38.01) 1 (12.50) 398 (10.56) 683 (6.10) 1819 (9.64)
Rash 1 (0.09) 14 (0.93) 16 (1.30) 0 65 (1.73) 125 (1.12) 222 (1.18)
Rheumatoid arthritis 0 2 (0.13) 7 (0.57) 0 1 (0.03) 47 (0.42) 57 (0.30)
SARS-CoV-2 test negative 7 (0.61) 14 (0.93) 10 (0.81) 0 27 (0.72) 13 (0.12) 71 (0.38)
SARS-CoV-2 test positive 34 (2.94) 20 (1.33) 1 (0.08) 0 85 (2.26) 38 (0.34) 179 (0.95)
Seizure 16 (1.38) 26 (1.72) 4 (0.32) 0 68 (1.80) 132 (1.18) 247 (1.31)
Sensory disturbance 0 4 (0.27) 11 (0.89) 0 27 (0.72) 46 (0.41) 89 (0.47)
Skin discolouration 1 (0.09) 8 (0.53) 3 (0.24) 0 13 (0.35) 38 (0.34) 63 (0.33)
Skin disorder 0 3 (0.20) 34 (2.76) 0 7 (0.19) 13 (0.12) 57 (0.30)
Sleep disorder 1 (0.09) 5 (0.33) 13 (1.05) 0 19 (0.50) 37 (0.33) 75 (0.40)
Somnolence 4 (0.35) 10 (0.66) 7 (0.57) 0 23 (0.61) 48 (0.43) 93 (0.49)
Speech disorder 2 (0.17) 16 (1.06) 14 (1.13) 1 (12.50) 38 (1.01) 34 (0.30) 106 (0.56)
Suspected COVID-19 48 (4.15) 9 (0.60) 0 0 50 (1.33) 423 (3.78) 530 (2.81)
Swelling 3 (0.26) 5 (0.33) 7 (0.57) 0 28 (0.74) 55 (0.49) 98 (0.52)
Swelling face 0 5 (0.33) 4 (0.32) 0 16 (0.42) 27 (0.24) 54 (0.29)
Syncope 14 (1.21) 45 (2.98) 22 (1.78) 0 103 (2.73) 437 (3.90) 623 (3.30)
Tachycardia 4 (0.35) 28 (1.86) 10 (0.81) 0 73 (1.94) 51 (0.46) 167 (0.89)
Therapy non-responder 1 (0.09) 0 2 (0.16) 0 8 (0.21) 416 (3.72) 427 (2.26)
Thrombocytopenia 42 (3.63) 74 (4.91) 3 (0.24) 0 115 (3.05) 47 (0.42) 282 (1.49)
Thrombosis 98 (8.47) 182 (12.07) 31 (2.51) 1 (12.50) 234 (6.21) 582 (5.20) 1129 (5.98)
Tinnitus 2 (0.17) 5 (0.33) 34 (2.76) 0 29 (0.77) 100 (0.89) 171 (0.91)
Transient ischaemic attack 3 (0.26) 16 (1.06) 6 (0.49) 0 47 (1.25) 40 (0.36) 112 (0.59)
Tremor 4 (0.35) 13 (0.86) 23 (1.86) 0 56 (1.49) 107 (0.96) 205 (1.09)
Troponin increased 8 (0.69) 20 (1.33) 1 (0.08) 0 38 (1.01) 3 (0.03) 70 (0.37)
Ultrasound Doppler 1 (0.09) 26 (1.72) 9 (0.73) 0 33 (0.88) 65 (0.58) 134 (0.71)
Ultrasound Doppler abnormal 5 (0.43) 95 (6.30) 10 (0.81) 0 53 (1.41) 61 (0.54) 224 (1.19)
Ultrasound scan 0 32 (2.12) 5 (0.41) 0 26 (0.69) 95 (0.85) 158 (0.84)
Ultrasound scan abnormal 2 (0.17) 17 (1.13) 4 (0.32) 0 12 (0.32) 83 (0.74) 118 (0.63)
Unresponsive to stimuli 22 (1.90) 13 (0.86) 0 0 9 (0.24) 10 (0.09) 56 (0.30)
Urticaria 0 3 (0.20) 10 (0.81) 0 14 (0.37) 53 (0.47) 81 (0.43)
Vaccination failure 152 (13.14) 45 (2.98) 2 (0.16) 0 252 (6.69) 5169 (46.17) 5623 (29.80)
Vaccination site pain 8 (0.69) 4 (0.27) 25 (2.03) 0 7 (0.19) 44 (0.39) 88 (0.47)
Vertigo 4 (0.35) 15 (0.99) 17 (1.38) 0 36 (0.96) 67 (0.60) 140 (0.74)
Vision blurred 1 (0.09) 18 (1.19) 29 (2.35) 0 53 (1.41) 110 (0.98) 212 (1.12)
Visual impairment 3 (0.26) 12 (0.80) 27 (2.19) 0 46 (1.22) 69 (0.62) 158 (0.84)
Vomiting 34 (2.94) 55 (3.65) 59 (4.78) 0 138 (3.66) 187 (1.67) 479 (2.54)
Weight decreased 4 (0.35) 6 (0.40) 6 (0.49) 0 34 (0.90) 46 (0.41) 98 (0.52)
X-ray 2 (0.17) 27 (1.79) 8 (0.65) 0 15 (0.40) 16 (0.14) 68 (0.36)