Eudravigilance C-19 - Moderna
Liste des effets indésirables (uniquement ceux qui apparaissent dans plus de 50 cas graves)
PT |
Décès 5518 (%) |
Mise en jeu du pronostic vital 6228 (%) |
Invalidité ou incapacité 8793 (%) |
Anomalies congénitales 146 (%) |
Hospitalisation 23622 (%) |
Médicalement significatif 52691 (%) |
Cas Graves 96998 (%) |
|---|---|---|---|---|---|---|---|
| Abdominal discomfort | 14 (0.25) | 20 (0.32) | 41 (0.47) | 1 (0.68) | 74 (0.31) | 116 (0.22) | 274 (0.28) |
| Abdominal distension | 12 (0.22) | 16 (0.26) | 11 (0.13) | 0 | 54 (0.23) | 54 (0.10) | 149 (0.15) |
| Abdominal pain | 38 (0.69) | 91 (1.46) | 113 (1.29) | 5 (3.42) | 474 (2.01) | 350 (0.66) | 1095 (1.13) |
| Abdominal pain lower | 2 (0.04) | 19 (0.31) | 11 (0.13) | 0 | 67 (0.28) | 31 (0.06) | 132 (0.14) |
| Abdominal pain upper | 32 (0.58) | 59 (0.95) | 105 (1.19) | 0 | 248 (1.05) | 622 (1.18) | 1071 (1.10) |
| Abnormal behaviour | 4 (0.07) | 7 (0.11) | 6 (0.07) | 0 | 37 (0.16) | 7 (0.01) | 65 (0.07) |
| Abortion spontaneous | 0 | 9 (0.14) | 18 (0.20) | 48 (32.88) | 39 (0.17) | 360 (0.68) | 478 (0.49) |
| Acute coronary syndrome | 5 (0.09) | 14 (0.22) | 0 | 0 | 43 (0.18) | 2 (0.00) | 65 (0.07) |
| Acute kidney injury | 97 (1.76) | 70 (1.12) | 10 (0.11) | 0 | 307 (1.30) | 29 (0.06) | 554 (0.57) |
| Acute myocardial infarction | 68 (1.23) | 133 (2.14) | 6 (0.07) | 0 | 222 (0.94) | 13 (0.02) | 455 (0.47) |
| Acute respiratory distress syndrome | 31 (0.56) | 14 (0.22) | 1 (0.01) | 0 | 25 (0.11) | 4 (0.01) | 83 (0.09) |
| Acute respiratory failure | 131 (2.37) | 50 (0.80) | 3 (0.03) | 0 | 311 (1.32) | 3 (0.01) | 509 (0.52) |
| Adverse drug reaction | 0 | 3 (0.05) | 18 (0.20) | 0 | 12 (0.05) | 76 (0.14) | 110 (0.11) |
| Ageusia | 9 (0.16) | 12 (0.19) | 56 (0.64) | 1 (0.68) | 81 (0.34) | 79 (0.15) | 242 (0.25) |
| Aggression | 4 (0.07) | 8 (0.13) | 6 (0.07) | 0 | 30 (0.13) | 3 (0.01) | 52 (0.05) |
| Agitation | 10 (0.18) | 7 (0.11) | 8 (0.09) | 0 | 32 (0.14) | 19 (0.04) | 81 (0.08) |
| Alopecia | 0 | 5 (0.08) | 36 (0.41) | 1 (0.68) | 19 (0.08) | 51 (0.10) | 113 (0.12) |
| Altered state of consciousness | 26 (0.47) | 13 (0.21) | 8 (0.09) | 0 | 74 (0.31) | 80 (0.15) | 214 (0.22) |
| Amenorrhoea | 0 | 2 (0.03) | 54 (0.61) | 1 (0.68) | 7 (0.03) | 86 (0.16) | 150 (0.15) |
| Amnesia | 6 (0.11) | 32 (0.51) | 61 (0.69) | 0 | 80 (0.34) | 61 (0.12) | 248 (0.26) |
| Anaemia | 17 (0.31) | 33 (0.53) | 13 (0.15) | 0 | 114 (0.48) | 22 (0.04) | 213 (0.22) |
| Anaphylactic reaction | 2 (0.04) | 236 (3.79) | 11 (0.13) | 0 | 314 (1.33) | 870 (1.65) | 1453 (1.50) |
| Anaphylactic shock | 3 (0.05) | 57 (0.92) | 1 (0.01) | 0 | 59 (0.25) | 60 (0.11) | 185 (0.19) |
| Anaphylactoid reaction | 0 | 4 (0.06) | 0 | 0 | 21 (0.09) | 42 (0.08) | 70 (0.07) |
| Angina pectoris | 7 (0.13) | 21 (0.34) | 27 (0.31) | 0 | 101 (0.43) | 246 (0.47) | 408 (0.42) |
| Angioedema | 0 | 41 (0.66) | 10 (0.11) | 0 | 66 (0.28) | 478 (0.91) | 606 (0.62) |
| Anosmia | 7 (0.13) | 8 (0.13) | 39 (0.44) | 0 | 61 (0.26) | 47 (0.09) | 166 (0.17) |
| Anticoagulant therapy | 10 (0.18) | 93 (1.49) | 12 (0.14) | 0 | 100 (0.42) | 0 | 216 (0.22) |
| Anxiety | 6 (0.11) | 32 (0.51) | 112 (1.27) | 1 (0.68) | 124 (0.52) | 141 (0.27) | 425 (0.44) |
| Aphasia | 18 (0.33) | 88 (1.41) | 73 (0.83) | 0 | 209 (0.88) | 22 (0.04) | 428 (0.44) |
| Appendicitis | 0 | 59 (0.95) | 1 (0.01) | 0 | 142 (0.60) | 38 (0.07) | 242 (0.25) |
| Arrhythmia | 25 (0.45) | 55 (0.88) | 50 (0.57) | 0 | 210 (0.89) | 419 (0.80) | 771 (0.79) |
| Arthralgia | 25 (0.45) | 138 (2.22) | 1469 (16.71) | 1 (0.68) | 492 (2.08) | 2236 (4.24) | 4388 (4.52) |
| Arthritis | 2 (0.04) | 6 (0.10) | 61 (0.69) | 0 | 29 (0.12) | 56 (0.11) | 154 (0.16) |
| Ascites | 11 (0.20) | 6 (0.10) | 2 (0.02) | 0 | 20 (0.08) | 8 (0.02) | 54 (0.06) |
| Aspiration | 12 (0.22) | 11 (0.18) | 0 | 0 | 16 (0.07) | 7 (0.01) | 54 (0.06) |
| Asthenia | 205 (3.72) | 306 (4.91) | 480 (5.46) | 1 (0.68) | 1433 (6.07) | 839 (1.59) | 3383 (3.49) |
| Asthma | 11 (0.20) | 45 (0.72) | 21 (0.24) | 0 | 91 (0.39) | 104 (0.20) | 274 (0.28) |
| Asymptomatic COVID-19 | 5 (0.09) | 1 (0.02) | 0 | 0 | 97 (0.41) | 10 (0.02) | 113 (0.12) |
| Ataxia | 1 (0.02) | 5 (0.08) | 9 (0.10) | 0 | 29 (0.12) | 6 (0.01) | 56 (0.06) |
| Atelectasis | 13 (0.24) | 16 (0.26) | 3 (0.03) | 0 | 105 (0.44) | 0 | 140 (0.14) |
| Atrial fibrillation | 57 (1.03) | 170 (2.73) | 45 (0.51) | 0 | 493 (2.09) | 548 (1.04) | 1352 (1.39) |
| Atrial flutter | 1 (0.02) | 15 (0.24) | 4 (0.05) | 0 | 47 (0.20) | 19 (0.04) | 91 (0.09) |
| Atrioventricular block | 3 (0.05) | 19 (0.31) | 1 (0.01) | 0 | 20 (0.08) | 7 (0.01) | 52 (0.05) |
| Autoimmune disorder | 2 (0.04) | 8 (0.13) | 25 (0.28) | 0 | 22 (0.09) | 76 (0.14) | 143 (0.15) |
| Axillary mass | 0 | 1 (0.02) | 16 (0.18) | 0 | 5 (0.02) | 34 (0.06) | 56 (0.06) |
| Axillary pain | 1 (0.02) | 9 (0.14) | 107 (1.22) | 0 | 31 (0.13) | 499 (0.95) | 649 (0.67) |
| Back pain | 41 (0.74) | 90 (1.45) | 249 (2.83) | 4 (2.74) | 288 (1.22) | 644 (1.22) | 1341 (1.38) |
| Balance disorder | 10 (0.18) | 33 (0.53) | 127 (1.44) | 0 | 150 (0.64) | 123 (0.23) | 454 (0.47) |
| Basedow's disease | 0 | 4 (0.06) | 12 (0.14) | 0 | 7 (0.03) | 27 (0.05) | 51 (0.05) |
| Bedridden | 7 (0.13) | 9 (0.14) | 17 (0.19) | 0 | 9 (0.04) | 28 (0.05) | 71 (0.07) |
| Bell's palsy | 0 | 7 (0.11) | 125 (1.42) | 1 (0.68) | 104 (0.44) | 1316 (2.50) | 1561 (1.61) |
| Blindness | 3 (0.05) | 16 (0.26) | 71 (0.81) | 0 | 47 (0.20) | 209 (0.40) | 355 (0.37) |
| Blindness transient | 0 | 0 | 6 (0.07) | 0 | 10 (0.04) | 50 (0.09) | 69 (0.07) |
| Blindness unilateral | 1 (0.02) | 10 (0.16) | 72 (0.82) | 0 | 24 (0.10) | 49 (0.09) | 163 (0.17) |
| Blister | 2 (0.04) | 13 (0.21) | 34 (0.39) | 0 | 39 (0.17) | 73 (0.14) | 163 (0.17) |
| Blood creatinine increased | 18 (0.33) | 10 (0.16) | 2 (0.02) | 0 | 58 (0.25) | 2 (0.00) | 93 (0.10) |
| Blood glucose increased | 11 (0.20) | 7 (0.11) | 6 (0.07) | 0 | 55 (0.23) | 14 (0.03) | 97 (0.10) |
| Blood glucose normal | 8 (0.14) | 7 (0.11) | 2 (0.02) | 0 | 36 (0.15) | 0 | 53 (0.05) |
| Blood pressure decreased | 6 (0.11) | 16 (0.26) | 18 (0.20) | 0 | 60 (0.25) | 48 (0.09) | 152 (0.16) |
| Blood pressure fluctuation | 1 (0.02) | 12 (0.19) | 10 (0.11) | 0 | 24 (0.10) | 6 (0.01) | 54 (0.06) |
| Blood pressure increased | 5 (0.09) | 49 (0.79) | 38 (0.43) | 1 (0.68) | 176 (0.75) | 99 (0.19) | 382 (0.39) |
| Blood test | 2 (0.04) | 57 (0.92) | 60 (0.68) | 0 | 78 (0.33) | 0 | 197 (0.20) |
| Blood urea increased | 14 (0.25) | 2 (0.03) | 0 | 0 | 34 (0.14) | 0 | 52 (0.05) |
| Body temperature | 0 | 1 (0.02) | 8 (0.09) | 0 | 2 (0.01) | 51 (0.10) | 62 (0.06) |
| Body temperature increased | 8 (0.14) | 10 (0.16) | 21 (0.24) | 0 | 66 (0.28) | 81 (0.15) | 190 (0.20) |
| Bone pain | 2 (0.04) | 16 (0.26) | 45 (0.51) | 0 | 22 (0.09) | 106 (0.20) | 193 (0.20) |
| Bradycardia | 20 (0.36) | 34 (0.55) | 8 (0.09) | 1 (0.68) | 73 (0.31) | 215 (0.41) | 362 (0.37) |
| Brain oedema | 10 (0.18) | 18 (0.29) | 5 (0.06) | 0 | 17 (0.07) | 14 (0.03) | 67 (0.07) |
| Breast pain | 2 (0.04) | 12 (0.19) | 32 (0.36) | 0 | 29 (0.12) | 87 (0.17) | 163 (0.17) |
| Bronchitis | 3 (0.05) | 7 (0.11) | 5 (0.06) | 0 | 41 (0.17) | 19 (0.04) | 76 (0.08) |
| Burning sensation | 2 (0.04) | 32 (0.51) | 112 (1.27) | 2 (1.37) | 52 (0.22) | 121 (0.23) | 326 (0.34) |
| Bursitis | 0 | 0 | 23 (0.26) | 0 | 9 (0.04) | 28 (0.05) | 61 (0.06) |
| C-reactive protein increased | 6 (0.11) | 10 (0.16) | 11 (0.13) | 0 | 110 (0.47) | 15 (0.03) | 154 (0.16) |
| COVID-19 | 656 (11.89) | 112 (1.80) | 51 (0.58) | 1 (0.68) | 3074 (13.01) | 3500 (6.64) | 7470 (7.70) |
| COVID-19 immunisation | 3 (0.05) | 32 (0.51) | 355 (4.04) | 0 | 83 (0.35) | 64 (0.12) | 538 (0.55) |
| COVID-19 pneumonia | 184 (3.33) | 23 (0.37) | 5 (0.06) | 0 | 570 (2.41) | 52 (0.10) | 857 (0.88) |
| Cardiac arrest | 401 (7.27) | 108 (1.73) | 3 (0.03) | 0 | 40 (0.17) | 11 (0.02) | 584 (0.60) |
| Cardiac discomfort | 3 (0.05) | 7 (0.11) | 7 (0.08) | 0 | 20 (0.08) | 17 (0.03) | 57 (0.06) |
| Cardiac disorder | 19 (0.34) | 31 (0.50) | 16 (0.18) | 0 | 57 (0.24) | 21 (0.04) | 153 (0.16) |
| Cardiac failure | 75 (1.36) | 52 (0.83) | 13 (0.15) | 0 | 122 (0.52) | 34 (0.06) | 312 (0.32) |
| Cardiac failure acute | 19 (0.34) | 7 (0.11) | 0 | 0 | 38 (0.16) | 0 | 66 (0.07) |
| Cardiac failure congestive | 39 (0.71) | 47 (0.75) | 10 (0.11) | 0 | 139 (0.59) | 28 (0.05) | 273 (0.28) |
| Cardiac flutter | 1 (0.02) | 13 (0.21) | 17 (0.19) | 0 | 31 (0.13) | 405 (0.77) | 471 (0.49) |
| Cardio-respiratory arrest | 125 (2.27) | 28 (0.45) | 0 | 0 | 12 (0.05) | 8 (0.02) | 183 (0.19) |
| Cardiogenic shock | 37 (0.67) | 17 (0.27) | 0 | 0 | 16 (0.07) | 3 (0.01) | 76 (0.08) |
| Cardiomegaly | 20 (0.36) | 26 (0.42) | 5 (0.06) | 1 (0.68) | 97 (0.41) | 9 (0.02) | 164 (0.17) |
| Cardiomyopathy | 6 (0.11) | 27 (0.43) | 6 (0.07) | 0 | 32 (0.14) | 17 (0.03) | 91 (0.09) |
| Cardiovascular disorder | 10 (0.18) | 7 (0.11) | 8 (0.09) | 0 | 20 (0.08) | 23 (0.04) | 73 (0.08) |
| Cellulitis | 5 (0.09) | 12 (0.19) | 11 (0.13) | 0 | 114 (0.48) | 924 (1.75) | 1082 (1.12) |
| Cerebral haemorrhage | 78 (1.41) | 64 (1.03) | 16 (0.18) | 0 | 83 (0.35) | 17 (0.03) | 268 (0.28) |
| Cerebral infarction | 13 (0.24) | 57 (0.92) | 32 (0.36) | 0 | 126 (0.53) | 15 (0.03) | 249 (0.26) |
| Cerebral thrombosis | 15 (0.27) | 32 (0.51) | 10 (0.11) | 0 | 47 (0.20) | 4 (0.01) | 110 (0.11) |
| Cerebral venous sinus thrombosis | 5 (0.09) | 51 (0.82) | 6 (0.07) | 0 | 55 (0.23) | 7 (0.01) | 124 (0.13) |
| Cerebrovascular accident | 144 (2.61) | 381 (6.12) | 194 (2.21) | 0 | 625 (2.65) | 238 (0.45) | 1630 (1.68) |
| Chest X-ray | 5 (0.09) | 28 (0.45) | 14 (0.16) | 0 | 51 (0.22) | 0 | 98 (0.10) |
| Chest X-ray abnormal | 27 (0.49) | 15 (0.24) | 2 (0.02) | 0 | 201 (0.85) | 0 | 246 (0.25) |
| Chest X-ray normal | 2 (0.04) | 6 (0.10) | 4 (0.05) | 0 | 62 (0.26) | 0 | 74 (0.08) |
| Chest discomfort | 34 (0.62) | 211 (3.39) | 117 (1.33) | 2 (1.37) | 622 (2.63) | 514 (0.98) | 1525 (1.57) |
| Chest pain | 98 (1.78) | 517 (8.30) | 354 (4.03) | 2 (1.37) | 1961 (8.30) | 1416 (2.69) | 4412 (4.55) |
| Chills | 81 (1.47) | 232 (3.73) | 1512 (17.20) | 6 (4.11) | 1124 (4.76) | 3550 (6.74) | 6564 (6.77) |
| Choking | 4 (0.07) | 7 (0.11) | 1 (0.01) | 0 | 12 (0.05) | 48 (0.09) | 73 (0.08) |
| Cholelithiasis | 2 (0.04) | 5 (0.08) | 3 (0.03) | 0 | 38 (0.16) | 0 | 52 (0.05) |
| Chromaturia | 1 (0.02) | 13 (0.21) | 8 (0.09) | 0 | 34 (0.14) | 19 (0.04) | 77 (0.08) |
| Chronic kidney disease | 12 (0.22) | 5 (0.08) | 3 (0.03) | 0 | 39 (0.17) | 11 (0.02) | 72 (0.07) |
| Chronic obstructive pulmonary disease | 25 (0.45) | 8 (0.13) | 2 (0.02) | 0 | 95 (0.40) | 7 (0.01) | 142 (0.15) |
| Circulatory collapse | 15 (0.27) | 12 (0.19) | 2 (0.02) | 0 | 21 (0.09) | 81 (0.15) | 139 (0.14) |
| Cluster headache | 0 | 1 (0.02) | 13 (0.15) | 0 | 5 (0.02) | 39 (0.07) | 58 (0.06) |
| Cognitive disorder | 10 (0.18) | 11 (0.18) | 62 (0.71) | 0 | 36 (0.15) | 20 (0.04) | 142 (0.15) |
| Cold sweat | 12 (0.22) | 23 (0.37) | 42 (0.48) | 0 | 84 (0.36) | 198 (0.38) | 369 (0.38) |
| Colitis | 3 (0.05) | 10 (0.16) | 3 (0.03) | 0 | 49 (0.21) | 10 (0.02) | 76 (0.08) |
| Colitis ulcerative | 0 | 1 (0.02) | 8 (0.09) | 0 | 20 (0.08) | 65 (0.12) | 96 (0.10) |
| Coma | 14 (0.25) | 19 (0.31) | 1 (0.01) | 0 | 17 (0.07) | 6 (0.01) | 65 (0.07) |
| Computerised tomogram | 5 (0.09) | 47 (0.75) | 33 (0.38) | 1 (0.68) | 55 (0.23) | 0 | 141 (0.15) |
| Computerised tomogram abdomen abnormal | 4 (0.07) | 10 (0.16) | 2 (0.02) | 0 | 35 (0.15) | 0 | 51 (0.05) |
| Computerised tomogram head normal | 2 (0.04) | 4 (0.06) | 6 (0.07) | 0 | 41 (0.17) | 0 | 53 (0.05) |
| Computerised tomogram thorax abnormal | 4 (0.07) | 31 (0.50) | 3 (0.03) | 0 | 61 (0.26) | 0 | 99 (0.10) |
| Condition aggravated | 141 (2.56) | 183 (2.94) | 356 (4.05) | 1 (0.68) | 693 (2.93) | 168 (0.32) | 1581 (1.63) |
| Confusional state | 61 (1.11) | 98 (1.57) | 139 (1.58) | 0 | 446 (1.89) | 200 (0.38) | 992 (1.02) |
| Conjunctival haemorrhage | 0 | 2 (0.03) | 3 (0.03) | 0 | 3 (0.01) | 55 (0.10) | 63 (0.06) |
| Constipation | 3 (0.05) | 8 (0.13) | 25 (0.28) | 0 | 64 (0.27) | 44 (0.08) | 146 (0.15) |
| Contusion | 3 (0.05) | 40 (0.64) | 52 (0.59) | 0 | 99 (0.42) | 174 (0.33) | 377 (0.39) |
| Coordination abnormal | 2 (0.04) | 7 (0.11) | 20 (0.23) | 0 | 25 (0.11) | 11 (0.02) | 66 (0.07) |
| Coronary artery disease | 17 (0.31) | 17 (0.27) | 4 (0.05) | 0 | 41 (0.17) | 1 (0.00) | 84 (0.09) |
| Coronary artery occlusion | 8 (0.14) | 34 (0.55) | 1 (0.01) | 0 | 29 (0.12) | 3 (0.01) | 78 (0.08) |
| Cough | 165 (2.99) | 157 (2.52) | 150 (1.71) | 1 (0.68) | 1116 (4.72) | 504 (0.96) | 2140 (2.21) |
| Crohn's disease | 0 | 1 (0.02) | 3 (0.03) | 0 | 13 (0.06) | 39 (0.07) | 59 (0.06) |
| Crying | 0 | 4 (0.06) | 19 (0.22) | 0 | 12 (0.05) | 18 (0.03) | 53 (0.05) |
| Cyanosis | 28 (0.51) | 14 (0.22) | 13 (0.15) | 0 | 27 (0.11) | 17 (0.03) | 104 (0.11) |
| Deafness | 1 (0.02) | 3 (0.05) | 96 (1.09) | 0 | 17 (0.07) | 346 (0.66) | 468 (0.48) |
| Deafness neurosensory | 0 | 2 (0.03) | 58 (0.66) | 0 | 2 (0.01) | 54 (0.10) | 118 (0.12) |
| Deafness unilateral | 0 | 2 (0.03) | 148 (1.68) | 0 | 12 (0.05) | 218 (0.41) | 386 (0.40) |
| Death | 2729 (49.46) | 1 (0.02) | 0 | 0 | 2 (0.01) | 2 (0.00) | 2734 (2.82) |
| Decreased appetite | 106 (1.92) | 71 (1.14) | 154 (1.75) | 1 (0.68) | 415 (1.76) | 423 (0.80) | 1212 (1.25) |
| Deep vein thrombosis | 24 (0.43) | 331 (5.31) | 19 (0.22) | 2 (1.37) | 392 (1.66) | 587 (1.11) | 1388 (1.43) |
| Dehydration | 22 (0.40) | 53 (0.85) | 31 (0.35) | 0 | 231 (0.98) | 68 (0.13) | 419 (0.43) |
| Delirium | 12 (0.22) | 20 (0.32) | 18 (0.20) | 0 | 39 (0.17) | 160 (0.30) | 260 (0.27) |
| Dementia | 14 (0.25) | 7 (0.11) | 9 (0.10) | 0 | 19 (0.08) | 34 (0.06) | 96 (0.10) |
| Depressed level of consciousness | 18 (0.33) | 20 (0.32) | 6 (0.07) | 0 | 57 (0.24) | 178 (0.34) | 295 (0.30) |
| Depressed mood | 1 (0.02) | 6 (0.10) | 18 (0.20) | 2 (1.37) | 4 (0.02) | 74 (0.14) | 106 (0.11) |
| Depression | 3 (0.05) | 20 (0.32) | 54 (0.61) | 1 (0.68) | 28 (0.12) | 71 (0.13) | 182 (0.19) |
| Dermatitis | 0 | 2 (0.03) | 11 (0.13) | 0 | 8 (0.03) | 29 (0.06) | 51 (0.05) |
| Dermatitis allergic | 0 | 2 (0.03) | 10 (0.11) | 0 | 9 (0.04) | 49 (0.09) | 71 (0.07) |
| Dermatitis bullous | 0 | 0 | 4 (0.05) | 0 | 8 (0.03) | 42 (0.08) | 54 (0.06) |
| Diabetes mellitus | 13 (0.24) | 16 (0.26) | 10 (0.11) | 0 | 25 (0.11) | 34 (0.06) | 101 (0.10) |
| Diabetic ketoacidosis | 5 (0.09) | 21 (0.34) | 3 (0.03) | 0 | 36 (0.15) | 3 (0.01) | 70 (0.07) |
| Diarrhoea | 73 (1.32) | 135 (2.17) | 255 (2.90) | 2 (1.37) | 748 (3.17) | 988 (1.88) | 2244 (2.31) |
| Diarrhoea haemorrhagic | 3 (0.05) | 6 (0.10) | 1 (0.01) | 0 | 12 (0.05) | 49 (0.09) | 73 (0.08) |
| Diplegia | 0 | 6 (0.10) | 13 (0.15) | 0 | 5 (0.02) | 26 (0.05) | 51 (0.05) |
| Diplopia | 0 | 25 (0.40) | 66 (0.75) | 0 | 95 (0.40) | 42 (0.08) | 233 (0.24) |
| Discomfort | 17 (0.31) | 21 (0.34) | 54 (0.61) | 0 | 78 (0.33) | 101 (0.19) | 278 (0.29) |
| Disease recurrence | 1 (0.02) | 1 (0.02) | 9 (0.10) | 0 | 14 (0.06) | 30 (0.06) | 55 (0.06) |
| Disorientation | 10 (0.18) | 35 (0.56) | 48 (0.55) | 0 | 93 (0.39) | 70 (0.13) | 263 (0.27) |
| Disturbance in attention | 1 (0.02) | 16 (0.26) | 75 (0.85) | 0 | 57 (0.24) | 118 (0.22) | 270 (0.28) |
| Diverticulitis | 0 | 2 (0.03) | 2 (0.02) | 0 | 45 (0.19) | 43 (0.08) | 93 (0.10) |
| Dizziness | 64 (1.16) | 354 (5.68) | 725 (8.25) | 4 (2.74) | 1370 (5.80) | 2380 (4.52) | 4973 (5.13) |
| Dizziness postural | 0 | 2 (0.03) | 22 (0.25) | 0 | 23 (0.10) | 159 (0.30) | 207 (0.21) |
| Drug ineffective | 14 (0.25) | 5 (0.08) | 2 (0.02) | 0 | 70 (0.30) | 49 (0.09) | 144 (0.15) |
| Dry eye | 0 | 1 (0.02) | 25 (0.28) | 0 | 7 (0.03) | 26 (0.05) | 59 (0.06) |
| Dry mouth | 0 | 10 (0.16) | 21 (0.24) | 0 | 32 (0.14) | 77 (0.15) | 141 (0.15) |
| Dry skin | 1 (0.02) | 1 (0.02) | 8 (0.09) | 0 | 3 (0.01) | 50 (0.09) | 63 (0.06) |
| Dysarthria | 11 (0.20) | 67 (1.08) | 57 (0.65) | 0 | 188 (0.80) | 41 (0.08) | 377 (0.39) |
| Dysgeusia | 1 (0.02) | 13 (0.21) | 24 (0.27) | 0 | 19 (0.08) | 137 (0.26) | 196 (0.20) |
| Dyskinesia | 1 (0.02) | 11 (0.18) | 22 (0.25) | 0 | 47 (0.20) | 21 (0.04) | 104 (0.11) |
| Dysmenorrhoea | 0 | 4 (0.06) | 75 (0.85) | 0 | 18 (0.08) | 316 (0.60) | 415 (0.43) |
| Dyspepsia | 6 (0.11) | 16 (0.26) | 23 (0.26) | 0 | 38 (0.16) | 120 (0.23) | 205 (0.21) |
| Dysphagia | 25 (0.45) | 84 (1.35) | 56 (0.64) | 0 | 140 (0.59) | 56 (0.11) | 382 (0.39) |
| Dysphonia | 5 (0.09) | 24 (0.39) | 19 (0.22) | 0 | 50 (0.21) | 32 (0.06) | 134 (0.14) |
| Dyspnoea | 491 (8.90) | 983 (15.78) | 545 (6.20) | 2 (1.37) | 3062 (12.96) | 1579 (3.00) | 6877 (7.09) |
| Dyspnoea exertional | 14 (0.25) | 67 (1.08) | 31 (0.35) | 0 | 191 (0.81) | 53 (0.10) | 371 (0.38) |
| Dysstasia | 8 (0.14) | 32 (0.51) | 87 (0.99) | 0 | 102 (0.43) | 24 (0.05) | 261 (0.27) |
| Dysuria | 2 (0.04) | 9 (0.14) | 9 (0.10) | 0 | 38 (0.16) | 20 (0.04) | 79 (0.08) |
| Ear discomfort | 0 | 8 (0.13) | 75 (0.85) | 0 | 17 (0.07) | 22 (0.04) | 123 (0.13) |
| Ear pain | 1 (0.02) | 10 (0.16) | 91 (1.03) | 1 (0.68) | 42 (0.18) | 217 (0.41) | 363 (0.37) |
| Echocardiogram | 2 (0.04) | 40 (0.64) | 20 (0.23) | 3 (2.05) | 73 (0.31) | 0 | 138 (0.14) |
| Echocardiogram abnormal | 4 (0.07) | 19 (0.31) | 7 (0.08) | 0 | 44 (0.19) | 0 | 75 (0.08) |
| Eczema | 0 | 1 (0.02) | 13 (0.15) | 0 | 11 (0.05) | 51 (0.10) | 76 (0.08) |
| Ejection fraction decreased | 6 (0.11) | 19 (0.31) | 2 (0.02) | 0 | 37 (0.16) | 1 (0.00) | 66 (0.07) |
| Electric shock sensation | 0 | 2 (0.03) | 29 (0.33) | 0 | 7 (0.03) | 11 (0.02) | 51 (0.05) |
| Electrocardiogram | 3 (0.05) | 38 (0.61) | 21 (0.24) | 0 | 51 (0.22) | 1 (0.00) | 114 (0.12) |
| Electrocardiogram abnormal | 7 (0.13) | 22 (0.35) | 8 (0.09) | 0 | 68 (0.29) | 1 (0.00) | 107 (0.11) |
| Electrocardiogram normal | 3 (0.05) | 11 (0.18) | 10 (0.11) | 0 | 41 (0.17) | 0 | 65 (0.07) |
| Encephalitis | 3 (0.05) | 17 (0.27) | 4 (0.05) | 0 | 47 (0.20) | 10 (0.02) | 85 (0.09) |
| Encephalopathy | 19 (0.34) | 21 (0.34) | 7 (0.08) | 0 | 89 (0.38) | 9 (0.02) | 152 (0.16) |
| Endotracheal intubation | 59 (1.07) | 27 (0.43) | 1 (0.01) | 0 | 39 (0.17) | 0 | 130 (0.13) |
| Epilepsy | 6 (0.11) | 25 (0.40) | 9 (0.10) | 0 | 93 (0.39) | 99 (0.19) | 235 (0.24) |
| Epistaxis | 14 (0.25) | 36 (0.58) | 26 (0.30) | 1 (0.68) | 62 (0.26) | 124 (0.24) | 269 (0.28) |
| Erectile dysfunction | 0 | 0 | 7 (0.08) | 0 | 1 (0.00) | 59 (0.11) | 67 (0.07) |
| Erysipelas | 1 (0.02) | 2 (0.03) | 5 (0.06) | 0 | 14 (0.06) | 81 (0.15) | 105 (0.11) |
| Erythema | 11 (0.20) | 76 (1.22) | 106 (1.21) | 2 (1.37) | 249 (1.05) | 522 (0.99) | 977 (1.01) |
| Erythema multiforme | 0 | 1 (0.02) | 1 (0.01) | 0 | 17 (0.07) | 185 (0.35) | 204 (0.21) |
| Exercise tolerance decreased | 0 | 5 (0.08) | 29 (0.33) | 0 | 17 (0.07) | 15 (0.03) | 71 (0.07) |
| Exposure during pregnancy | 0 | 10 (0.16) | 7 (0.08) | 23 (15.75) | 79 (0.33) | 31 (0.06) | 153 (0.16) |
| Exposure to SARS-CoV-2 | 13 (0.24) | 3 (0.05) | 2 (0.02) | 0 | 79 (0.33) | 3 (0.01) | 103 (0.11) |
| Extensive swelling of vaccinated limb | 1 (0.02) | 6 (0.10) | 279 (3.17) | 0 | 9 (0.04) | 36 (0.07) | 331 (0.34) |
| Extrasystoles | 1 (0.02) | 19 (0.31) | 25 (0.28) | 0 | 22 (0.09) | 48 (0.09) | 115 (0.12) |
| Eye haemorrhage | 1 (0.02) | 3 (0.05) | 9 (0.10) | 0 | 7 (0.03) | 101 (0.19) | 128 (0.13) |
| Eye irritation | 0 | 2 (0.03) | 14 (0.16) | 0 | 13 (0.06) | 21 (0.04) | 51 (0.05) |
| Eye movement disorder | 3 (0.05) | 7 (0.11) | 12 (0.14) | 0 | 23 (0.10) | 5 (0.01) | 52 (0.05) |
| Eye pain | 0 | 10 (0.16) | 110 (1.25) | 0 | 52 (0.22) | 248 (0.47) | 424 (0.44) |
| Eye swelling | 0 | 18 (0.29) | 26 (0.30) | 0 | 22 (0.09) | 87 (0.17) | 155 (0.16) |
| Face oedema | 0 | 6 (0.10) | 4 (0.05) | 0 | 20 (0.08) | 49 (0.09) | 79 (0.08) |
| Facial pain | 0 | 3 (0.05) | 28 (0.32) | 0 | 17 (0.07) | 40 (0.08) | 89 (0.09) |
| Facial paralysis | 1 (0.02) | 44 (0.71) | 113 (1.29) | 1 (0.68) | 259 (1.10) | 866 (1.64) | 1305 (1.35) |
| Facial paresis | 1 (0.02) | 6 (0.10) | 27 (0.31) | 0 | 70 (0.30) | 54 (0.10) | 160 (0.16) |
| Fall | 94 (1.70) | 95 (1.53) | 111 (1.26) | 0 | 540 (2.29) | 88 (0.17) | 981 (1.01) |
| Fatigue | 179 (3.24) | 440 (7.06) | 2359 (26.83) | 9 (6.16) | 1610 (6.82) | 5090 (9.66) | 9796 (10.10) |
| Fear | 1 (0.02) | 7 (0.11) | 20 (0.23) | 0 | 16 (0.07) | 7 (0.01) | 51 (0.05) |
| Feeding disorder | 8 (0.14) | 16 (0.26) | 23 (0.26) | 0 | 58 (0.25) | 42 (0.08) | 154 (0.16) |
| Feeling abnormal | 37 (0.67) | 110 (1.77) | 250 (2.84) | 2 (1.37) | 326 (1.38) | 330 (0.63) | 1085 (1.12) |
| Feeling cold | 6 (0.11) | 31 (0.50) | 79 (0.90) | 0 | 59 (0.25) | 306 (0.58) | 484 (0.50) |
| Feeling hot | 8 (0.14) | 27 (0.43) | 78 (0.89) | 0 | 150 (0.64) | 262 (0.50) | 529 (0.55) |
| Feeling of body temperature change | 3 (0.05) | 4 (0.06) | 42 (0.48) | 1 (0.68) | 25 (0.11) | 106 (0.20) | 182 (0.19) |
| Fibrin D dimer | 3 (0.05) | 17 (0.27) | 3 (0.03) | 0 | 43 (0.18) | 1 (0.00) | 67 (0.07) |
| Fibrin D dimer increased | 10 (0.18) | 21 (0.34) | 9 (0.10) | 0 | 104 (0.44) | 34 (0.06) | 182 (0.19) |
| Fibromyalgia | 0 | 0 | 26 (0.30) | 0 | 5 (0.02) | 22 (0.04) | 53 (0.05) |
| Flank pain | 3 (0.05) | 21 (0.34) | 17 (0.19) | 0 | 44 (0.19) | 14 (0.03) | 99 (0.10) |
| Fluid retention | 5 (0.09) | 7 (0.11) | 12 (0.14) | 0 | 24 (0.10) | 6 (0.01) | 56 (0.06) |
| Flushing | 2 (0.04) | 31 (0.50) | 17 (0.19) | 0 | 68 (0.29) | 62 (0.12) | 181 (0.19) |
| Foetal death | 4 (0.07) | 3 (0.05) | 1 (0.01) | 10 (6.85) | 18 (0.08) | 25 (0.05) | 63 (0.06) |
| Full blood count | 7 (0.13) | 18 (0.29) | 13 (0.15) | 1 (0.68) | 64 (0.27) | 0 | 104 (0.11) |
| Gait disturbance | 13 (0.24) | 80 (1.28) | 223 (2.54) | 0 | 333 (1.41) | 104 (0.20) | 785 (0.81) |
| Gait inability | 17 (0.31) | 48 (0.77) | 118 (1.34) | 1 (0.68) | 162 (0.69) | 25 (0.05) | 382 (0.39) |
| Gastrointestinal disorder | 5 (0.09) | 6 (0.10) | 10 (0.11) | 0 | 23 (0.10) | 15 (0.03) | 59 (0.06) |
| Gastrointestinal haemorrhage | 21 (0.38) | 21 (0.34) | 1 (0.01) | 0 | 48 (0.20) | 19 (0.04) | 115 (0.12) |
| Gastrointestinal pain | 0 | 1 (0.02) | 12 (0.14) | 0 | 14 (0.06) | 31 (0.06) | 59 (0.06) |
| Gastrooesophageal reflux disease | 2 (0.04) | 12 (0.19) | 9 (0.10) | 0 | 31 (0.13) | 27 (0.05) | 81 (0.08) |
| Gaze palsy | 2 (0.04) | 7 (0.11) | 4 (0.05) | 0 | 13 (0.06) | 67 (0.13) | 96 (0.10) |
| General physical health deterioration | 125 (2.27) | 22 (0.35) | 26 (0.30) | 0 | 74 (0.31) | 18 (0.03) | 292 (0.30) |
| Generalised tonic-clonic seizure | 4 (0.07) | 18 (0.29) | 7 (0.08) | 0 | 54 (0.23) | 110 (0.21) | 196 (0.20) |
| Gout | 0 | 1 (0.02) | 15 (0.17) | 0 | 20 (0.08) | 16 (0.03) | 54 (0.06) |
| Grip strength decreased | 2 (0.04) | 4 (0.06) | 27 (0.31) | 0 | 13 (0.06) | 9 (0.02) | 55 (0.06) |
| Groin pain | 1 (0.02) | 7 (0.11) | 18 (0.20) | 0 | 14 (0.06) | 21 (0.04) | 65 (0.07) |
| Guillain-Barre syndrome | 5 (0.09) | 67 (1.08) | 77 (0.88) | 0 | 184 (0.78) | 78 (0.15) | 417 (0.43) |
| Haematemesis | 14 (0.25) | 8 (0.13) | 1 (0.01) | 0 | 18 (0.08) | 54 (0.10) | 98 (0.10) |
| Haematochezia | 4 (0.07) | 5 (0.08) | 8 (0.09) | 0 | 38 (0.16) | 154 (0.29) | 218 (0.22) |
| Haematoma | 6 (0.11) | 15 (0.24) | 14 (0.16) | 0 | 34 (0.14) | 40 (0.08) | 112 (0.12) |
| Haematuria | 5 (0.09) | 9 (0.14) | 6 (0.07) | 0 | 38 (0.16) | 30 (0.06) | 95 (0.10) |
| Haemoglobin decreased | 17 (0.31) | 16 (0.26) | 1 (0.01) | 0 | 70 (0.30) | 5 (0.01) | 111 (0.11) |
| Haemoptysis | 14 (0.25) | 28 (0.45) | 3 (0.03) | 0 | 39 (0.17) | 9 (0.02) | 99 (0.10) |
| Haemorrhage | 23 (0.42) | 26 (0.42) | 18 (0.20) | 1 (0.68) | 51 (0.22) | 332 (0.63) | 467 (0.48) |
| Haemorrhagic stroke | 26 (0.47) | 13 (0.21) | 3 (0.03) | 0 | 20 (0.08) | 6 (0.01) | 71 (0.07) |
| Hallucination | 5 (0.09) | 7 (0.11) | 25 (0.28) | 0 | 56 (0.24) | 386 (0.73) | 491 (0.51) |
| Hallucination, auditory | 0 | 2 (0.03) | 2 (0.02) | 0 | 10 (0.04) | 38 (0.07) | 53 (0.05) |
| Hallucination, visual | 0 | 0 | 5 (0.06) | 0 | 7 (0.03) | 46 (0.09) | 60 (0.06) |
| Head discomfort | 1 (0.02) | 8 (0.13) | 51 (0.58) | 0 | 36 (0.15) | 56 (0.11) | 155 (0.16) |
| Head injury | 14 (0.25) | 20 (0.32) | 11 (0.13) | 0 | 84 (0.36) | 26 (0.05) | 161 (0.17) |
| Headache | 93 (1.69) | 458 (7.35) | 2337 (26.58) | 10 (6.85) | 1798 (7.61) | 6845 (12.99) | 11642 (12.00) |
| Heart rate | 0 | 3 (0.05) | 13 (0.15) | 0 | 17 (0.07) | 118 (0.22) | 151 (0.16) |
| Heart rate decreased | 5 (0.09) | 10 (0.16) | 3 (0.03) | 0 | 28 (0.12) | 16 (0.03) | 63 (0.06) |
| Heart rate increased | 10 (0.18) | 83 (1.33) | 118 (1.34) | 2 (1.37) | 223 (0.94) | 297 (0.56) | 749 (0.77) |
| Heart rate irregular | 4 (0.07) | 14 (0.22) | 31 (0.35) | 0 | 48 (0.20) | 65 (0.12) | 165 (0.17) |
| Heavy menstrual bleeding | 0 | 17 (0.27) | 118 (1.34) | 2 (1.37) | 47 (0.20) | 571 (1.08) | 756 (0.78) |
| Hemiparesis | 9 (0.16) | 53 (0.85) | 74 (0.84) | 0 | 160 (0.68) | 106 (0.20) | 421 (0.43) |
| Hemiplegia | 6 (0.11) | 31 (0.50) | 39 (0.44) | 0 | 43 (0.18) | 45 (0.09) | 176 (0.18) |
| Herpes zoster | 6 (0.11) | 17 (0.27) | 80 (0.91) | 0 | 132 (0.56) | 371 (0.70) | 612 (0.63) |
| Hospitalisation | 10 (0.18) | 2 (0.03) | 0 | 0 | 222 (0.94) | 0 | 250 (0.26) |
| Hot flush | 0 | 17 (0.27) | 47 (0.53) | 1 (0.68) | 35 (0.15) | 205 (0.39) | 307 (0.32) |
| Hyperaesthesia | 1 (0.02) | 1 (0.02) | 24 (0.27) | 1 (0.68) | 5 (0.02) | 38 (0.07) | 71 (0.07) |
| Hyperglycaemia | 5 (0.09) | 12 (0.19) | 1 (0.01) | 0 | 48 (0.20) | 12 (0.02) | 83 (0.09) |
| Hyperhidrosis | 23 (0.42) | 113 (1.81) | 207 (2.35) | 0 | 301 (1.27) | 774 (1.47) | 1434 (1.48) |
| Hyperkalaemia | 12 (0.22) | 3 (0.05) | 0 | 0 | 30 (0.13) | 6 (0.01) | 61 (0.06) |
| Hyperpyrexia | 9 (0.16) | 11 (0.18) | 6 (0.07) | 0 | 30 (0.13) | 227 (0.43) | 285 (0.29) |
| Hypersensitivity | 5 (0.09) | 78 (1.25) | 49 (0.56) | 1 (0.68) | 179 (0.76) | 390 (0.74) | 708 (0.73) |
| Hypersomnia | 5 (0.09) | 20 (0.32) | 27 (0.31) | 1 (0.68) | 29 (0.12) | 36 (0.07) | 123 (0.13) |
| Hypertension | 38 (0.69) | 132 (2.12) | 82 (0.93) | 1 (0.68) | 446 (1.89) | 277 (0.53) | 1004 (1.04) |
| Hypertensive crisis | 3 (0.05) | 20 (0.32) | 0 | 0 | 44 (0.19) | 71 (0.13) | 140 (0.14) |
| Hyperthyroidism | 1 (0.02) | 5 (0.08) | 12 (0.14) | 0 | 6 (0.03) | 56 (0.11) | 80 (0.08) |
| Hyperventilation | 4 (0.07) | 8 (0.13) | 2 (0.02) | 0 | 45 (0.19) | 16 (0.03) | 77 (0.08) |
| Hypervolaemia | 6 (0.11) | 3 (0.05) | 0 | 0 | 39 (0.17) | 0 | 53 (0.05) |
| Hypoacusis | 2 (0.04) | 5 (0.08) | 90 (1.02) | 0 | 32 (0.14) | 54 (0.10) | 185 (0.19) |
| Hypoaesthesia | 5 (0.09) | 144 (2.31) | 465 (5.29) | 0 | 611 (2.59) | 542 (1.03) | 1797 (1.85) |
| Hypoaesthesia oral | 1 (0.02) | 15 (0.24) | 39 (0.44) | 0 | 65 (0.28) | 61 (0.12) | 185 (0.19) |
| Hypoglycaemia | 6 (0.11) | 10 (0.16) | 4 (0.05) | 0 | 22 (0.09) | 14 (0.03) | 58 (0.06) |
| Hypokalaemia | 9 (0.16) | 7 (0.11) | 2 (0.02) | 0 | 56 (0.24) | 24 (0.05) | 105 (0.11) |
| Hypokinesia | 3 (0.05) | 3 (0.05) | 18 (0.20) | 0 | 30 (0.13) | 23 (0.04) | 81 (0.08) |
| Hyponatraemia | 12 (0.22) | 14 (0.22) | 3 (0.03) | 0 | 82 (0.35) | 3 (0.01) | 125 (0.13) |
| Hypophagia | 20 (0.36) | 14 (0.22) | 5 (0.06) | 0 | 94 (0.40) | 2 (0.00) | 142 (0.15) |
| Hypopnoea | 8 (0.14) | 11 (0.18) | 5 (0.06) | 0 | 14 (0.06) | 19 (0.04) | 61 (0.06) |
| Hypotension | 90 (1.63) | 88 (1.41) | 40 (0.45) | 0 | 297 (1.26) | 156 (0.30) | 702 (0.72) |
| Hypothermia | 2 (0.04) | 4 (0.06) | 2 (0.02) | 0 | 10 (0.04) | 37 (0.07) | 57 (0.06) |
| Hypothyroidism | 2 (0.04) | 3 (0.05) | 9 (0.10) | 0 | 16 (0.07) | 30 (0.06) | 64 (0.07) |
| Hypotonia | 4 (0.07) | 5 (0.08) | 10 (0.11) | 0 | 24 (0.10) | 14 (0.03) | 57 (0.06) |
| Hypoxia | 129 (2.34) | 71 (1.14) | 4 (0.05) | 0 | 491 (2.08) | 57 (0.11) | 792 (0.82) |
| Illness | 30 (0.54) | 23 (0.37) | 72 (0.82) | 2 (1.37) | 85 (0.36) | 471 (0.89) | 696 (0.72) |
| Immediate post-injection reaction | 7 (0.13) | 30 (0.48) | 60 (0.68) | 1 (0.68) | 42 (0.18) | 3 (0.01) | 143 (0.15) |
| Immune thrombocytopenia | 4 (0.07) | 68 (1.09) | 4 (0.05) | 0 | 118 (0.50) | 47 (0.09) | 243 (0.25) |
| Immunisation reaction | 0 | 0 | 0 | 0 | 3 (0.01) | 72 (0.14) | 75 (0.08) |
| Impaired driving ability | 3 (0.05) | 20 (0.32) | 49 (0.56) | 0 | 31 (0.13) | 12 (0.02) | 119 (0.12) |
| Impaired work ability | 5 (0.09) | 56 (0.90) | 211 (2.40) | 2 (1.37) | 90 (0.38) | 66 (0.13) | 445 (0.46) |
| Inappropriate schedule of product administration | 8 (0.14) | 5 (0.08) | 14 (0.16) | 2 (1.37) | 53 (0.22) | 10 (0.02) | 93 (0.10) |
| Infection | 8 (0.14) | 14 (0.22) | 21 (0.24) | 0 | 98 (0.41) | 52 (0.10) | 196 (0.20) |
| Inflammation | 7 (0.13) | 34 (0.55) | 94 (1.07) | 0 | 119 (0.50) | 96 (0.18) | 356 (0.37) |
| Influenza | 2 (0.04) | 13 (0.21) | 54 (0.61) | 0 | 96 (0.41) | 444 (0.84) | 611 (0.63) |
| Influenza like illness | 15 (0.27) | 37 (0.59) | 254 (2.89) | 0 | 223 (0.94) | 840 (1.59) | 1379 (1.42) |
| Injected limb mobility decreased | 2 (0.04) | 6 (0.10) | 107 (1.22) | 0 | 8 (0.03) | 32 (0.06) | 156 (0.16) |
| Injection site erythema | 3 (0.05) | 13 (0.21) | 88 (1.00) | 1 (0.68) | 77 (0.33) | 184 (0.35) | 366 (0.38) |
| Injection site mass | 1 (0.02) | 1 (0.02) | 12 (0.14) | 0 | 4 (0.02) | 86 (0.16) | 104 (0.11) |
| Injection site pain | 15 (0.27) | 35 (0.56) | 266 (3.03) | 1 (0.68) | 187 (0.79) | 734 (1.39) | 1245 (1.28) |
| Injection site pruritus | 3 (0.05) | 7 (0.11) | 33 (0.38) | 1 (0.68) | 19 (0.08) | 62 (0.12) | 125 (0.13) |
| Injection site rash | 0 | 8 (0.13) | 20 (0.23) | 0 | 17 (0.07) | 92 (0.17) | 137 (0.14) |
| Injection site reaction | 2 (0.04) | 6 (0.10) | 839 (9.54) | 1 (0.68) | 36 (0.15) | 145 (0.28) | 1030 (1.06) |
| Injection site swelling | 3 (0.05) | 17 (0.27) | 75 (0.85) | 0 | 78 (0.33) | 117 (0.22) | 293 (0.30) |
| Injection site warmth | 1 (0.02) | 8 (0.13) | 33 (0.38) | 0 | 11 (0.05) | 59 (0.11) | 112 (0.12) |
| Insomnia | 12 (0.22) | 26 (0.42) | 169 (1.92) | 2 (1.37) | 79 (0.33) | 426 (0.81) | 724 (0.75) |
| Intensive care | 44 (0.80) | 57 (0.92) | 3 (0.03) | 0 | 74 (0.31) | 0 | 178 (0.18) |
| Interchange of vaccine products | 1 (0.02) | 8 (0.13) | 9 (0.10) | 0 | 23 (0.10) | 53 (0.10) | 97 (0.10) |
| Intermenstrual bleeding | 0 | 3 (0.05) | 26 (0.30) | 2 (1.37) | 13 (0.06) | 167 (0.32) | 211 (0.22) |
| Interstitial lung disease | 11 (0.20) | 11 (0.18) | 3 (0.03) | 0 | 41 (0.17) | 8 (0.02) | 80 (0.08) |
| Intracardiac thrombus | 8 (0.14) | 21 (0.34) | 5 (0.06) | 0 | 14 (0.06) | 1 (0.00) | 52 (0.05) |
| Irritability | 2 (0.04) | 5 (0.08) | 11 (0.13) | 0 | 11 (0.05) | 35 (0.07) | 64 (0.07) |
| Ischaemic stroke | 25 (0.45) | 69 (1.11) | 37 (0.42) | 0 | 196 (0.83) | 22 (0.04) | 353 (0.36) |
| Jaundice | 3 (0.05) | 5 (0.08) | 2 (0.02) | 0 | 32 (0.14) | 8 (0.02) | 55 (0.06) |
| Joint range of motion decreased | 1 (0.02) | 7 (0.11) | 60 (0.68) | 0 | 14 (0.06) | 3 (0.01) | 86 (0.09) |
| Joint stiffness | 1 (0.02) | 4 (0.06) | 41 (0.47) | 0 | 13 (0.06) | 56 (0.11) | 117 (0.12) |
| Joint swelling | 2 (0.04) | 21 (0.34) | 89 (1.01) | 0 | 52 (0.22) | 69 (0.13) | 238 (0.25) |
| Kidney infection | 1 (0.02) | 4 (0.06) | 5 (0.06) | 0 | 19 (0.08) | 24 (0.05) | 53 (0.05) |
| Laboratory test | 13 (0.24) | 47 (0.75) | 38 (0.43) | 1 (0.68) | 67 (0.28) | 0 | 166 (0.17) |
| Lacrimation increased | 1 (0.02) | 5 (0.08) | 16 (0.18) | 0 | 10 (0.04) | 24 (0.05) | 56 (0.06) |
| Lactic acidosis | 15 (0.27) | 8 (0.13) | 1 (0.01) | 0 | 35 (0.15) | 2 (0.00) | 64 (0.07) |
| Lethargy | 46 (0.83) | 49 (0.79) | 60 (0.68) | 1 (0.68) | 166 (0.70) | 341 (0.65) | 677 (0.70) |
| Leukocytosis | 10 (0.18) | 9 (0.14) | 3 (0.03) | 0 | 85 (0.36) | 3 (0.01) | 118 (0.12) |
| Leukopenia | 5 (0.09) | 6 (0.10) | 1 (0.01) | 0 | 26 (0.11) | 16 (0.03) | 57 (0.06) |
| Limb discomfort | 3 (0.05) | 27 (0.43) | 84 (0.96) | 0 | 142 (0.60) | 239 (0.45) | 503 (0.52) |
| Limb injury | 1 (0.02) | 3 (0.05) | 19 (0.22) | 0 | 17 (0.07) | 34 (0.06) | 75 (0.08) |
| Lip swelling | 1 (0.02) | 42 (0.67) | 20 (0.23) | 2 (1.37) | 83 (0.35) | 133 (0.25) | 288 (0.30) |
| Loss of consciousness | 93 (1.69) | 199 (3.20) | 73 (0.83) | 1 (0.68) | 480 (2.03) | 2953 (5.60) | 3910 (4.03) |
| Loss of personal independence in daily activities | 4 (0.07) | 47 (0.75) | 181 (2.06) | 0 | 84 (0.36) | 29 (0.06) | 363 (0.37) |
| Lower respiratory tract infection | 1 (0.02) | 5 (0.08) | 10 (0.11) | 0 | 12 (0.05) | 67 (0.13) | 96 (0.10) |
| Lung consolidation | 7 (0.13) | 3 (0.05) | 1 (0.01) | 0 | 40 (0.17) | 0 | 54 (0.06) |
| Lung disorder | 13 (0.24) | 7 (0.11) | 7 (0.08) | 0 | 70 (0.30) | 9 (0.02) | 110 (0.11) |
| Lung infiltration | 30 (0.54) | 21 (0.34) | 0 | 0 | 151 (0.64) | 0 | 215 (0.22) |
| Lung opacity | 37 (0.67) | 43 (0.69) | 4 (0.05) | 0 | 219 (0.93) | 1 (0.00) | 310 (0.32) |
| Lymph node pain | 1 (0.02) | 3 (0.05) | 35 (0.40) | 0 | 15 (0.06) | 182 (0.35) | 237 (0.24) |
| Lymphadenitis | 0 | 2 (0.03) | 12 (0.14) | 0 | 17 (0.07) | 37 (0.07) | 68 (0.07) |
| Lymphadenopathy | 10 (0.18) | 55 (0.88) | 284 (3.23) | 1 (0.68) | 229 (0.97) | 1328 (2.52) | 1921 (1.98) |
| Magnetic resonance imaging | 3 (0.05) | 25 (0.40) | 44 (0.50) | 1 (0.68) | 38 (0.16) | 0 | 111 (0.11) |
| Magnetic resonance imaging head abnormal | 3 (0.05) | 14 (0.22) | 17 (0.19) | 0 | 19 (0.08) | 0 | 53 (0.05) |
| Malaise | 181 (3.28) | 196 (3.15) | 1116 (12.69) | 8 (5.48) | 836 (3.54) | 1036 (1.97) | 3437 (3.54) |
| Maternal exposure during breast feeding | 0 | 2 (0.03) | 11 (0.13) | 0 | 5 (0.02) | 223 (0.42) | 241 (0.25) |
| Maternal exposure during pregnancy | 1 (0.02) | 16 (0.26) | 13 (0.15) | 23 (15.75) | 68 (0.29) | 196 (0.37) | 319 (0.33) |
| Mechanical ventilation | 30 (0.54) | 11 (0.18) | 2 (0.02) | 0 | 13 (0.06) | 0 | 58 (0.06) |
| Memory impairment | 6 (0.11) | 23 (0.37) | 70 (0.80) | 0 | 109 (0.46) | 44 (0.08) | 260 (0.27) |
| Menstrual disorder | 0 | 3 (0.05) | 67 (0.76) | 1 (0.68) | 27 (0.11) | 212 (0.40) | 313 (0.32) |
| Menstruation delayed | 0 | 1 (0.02) | 38 (0.43) | 0 | 4 (0.02) | 239 (0.45) | 282 (0.29) |
| Menstruation irregular | 0 | 1 (0.02) | 64 (0.73) | 2 (1.37) | 18 (0.08) | 236 (0.45) | 323 (0.33) |
| Mental fatigue | 0 | 1 (0.02) | 18 (0.20) | 0 | 2 (0.01) | 31 (0.06) | 52 (0.05) |
| Mental impairment | 3 (0.05) | 3 (0.05) | 29 (0.33) | 0 | 18 (0.08) | 171 (0.32) | 233 (0.24) |
| Mental status changes | 44 (0.80) | 44 (0.71) | 9 (0.10) | 0 | 206 (0.87) | 2 (0.00) | 318 (0.33) |
| Metabolic function test | 5 (0.09) | 16 (0.26) | 10 (0.11) | 0 | 45 (0.19) | 0 | 76 (0.08) |
| Migraine | 3 (0.05) | 35 (0.56) | 233 (2.65) | 0 | 134 (0.57) | 640 (1.21) | 1051 (1.08) |
| Migraine with aura | 0 | 0 | 11 (0.13) | 2 (1.37) | 10 (0.04) | 35 (0.07) | 58 (0.06) |
| Mitral valve incompetence | 3 (0.05) | 9 (0.14) | 2 (0.02) | 0 | 32 (0.14) | 6 (0.01) | 54 (0.06) |
| Mobility decreased | 19 (0.34) | 73 (1.17) | 212 (2.41) | 2 (1.37) | 207 (0.88) | 43 (0.08) | 572 (0.59) |
| Monoplegia | 0 | 6 (0.10) | 24 (0.27) | 0 | 24 (0.10) | 115 (0.22) | 173 (0.18) |
| Motor dysfunction | 3 (0.05) | 5 (0.08) | 16 (0.18) | 0 | 31 (0.13) | 8 (0.02) | 64 (0.07) |
| Mouth swelling | 0 | 13 (0.21) | 5 (0.06) | 0 | 21 (0.09) | 16 (0.03) | 57 (0.06) |
| Mouth ulceration | 0 | 4 (0.06) | 6 (0.07) | 0 | 12 (0.05) | 37 (0.07) | 59 (0.06) |
| Movement disorder | 6 (0.11) | 11 (0.18) | 50 (0.57) | 0 | 47 (0.20) | 25 (0.05) | 145 (0.15) |
| Multiple organ dysfunction syndrome | 51 (0.92) | 8 (0.13) | 0 | 0 | 6 (0.03) | 1 (0.00) | 78 (0.08) |
| Multiple sclerosis | 0 | 4 (0.06) | 28 (0.32) | 0 | 22 (0.09) | 65 (0.12) | 120 (0.12) |
| Multiple sclerosis relapse | 0 | 1 (0.02) | 9 (0.10) | 0 | 24 (0.10) | 39 (0.07) | 73 (0.08) |
| Muscle fatigue | 0 | 2 (0.03) | 18 (0.20) | 0 | 6 (0.03) | 68 (0.13) | 95 (0.10) |
| Muscle rigidity | 3 (0.05) | 9 (0.14) | 10 (0.11) | 0 | 15 (0.06) | 14 (0.03) | 51 (0.05) |
| Muscle spasms | 7 (0.13) | 49 (0.79) | 141 (1.60) | 3 (2.05) | 147 (0.62) | 343 (0.65) | 700 (0.72) |
| Muscle tightness | 1 (0.02) | 13 (0.21) | 18 (0.20) | 1 (0.68) | 23 (0.10) | 22 (0.04) | 81 (0.08) |
| Muscle twitching | 2 (0.04) | 8 (0.13) | 53 (0.60) | 1 (0.68) | 32 (0.14) | 55 (0.10) | 153 (0.16) |
| Muscular weakness | 20 (0.36) | 80 (1.28) | 293 (3.33) | 1 (0.68) | 439 (1.86) | 246 (0.47) | 1107 (1.14) |
| Musculoskeletal chest pain | 1 (0.02) | 15 (0.24) | 23 (0.26) | 0 | 42 (0.18) | 56 (0.11) | 141 (0.15) |
| Musculoskeletal discomfort | 2 (0.04) | 6 (0.10) | 17 (0.19) | 0 | 18 (0.08) | 21 (0.04) | 66 (0.07) |
| Musculoskeletal pain | 2 (0.04) | 2 (0.03) | 22 (0.25) | 1 (0.68) | 35 (0.15) | 120 (0.23) | 183 (0.19) |
| Musculoskeletal stiffness | 5 (0.09) | 19 (0.31) | 187 (2.13) | 0 | 92 (0.39) | 316 (0.60) | 624 (0.64) |
| Myalgia | 35 (0.63) | 160 (2.57) | 1722 (19.58) | 3 (2.05) | 723 (3.06) | 2947 (5.59) | 5630 (5.80) |
| Myasthenia gravis | 1 (0.02) | 9 (0.14) | 19 (0.22) | 0 | 21 (0.09) | 31 (0.06) | 83 (0.09) |
| Myelitis transverse | 0 | 3 (0.05) | 37 (0.42) | 0 | 32 (0.14) | 17 (0.03) | 94 (0.10) |
| Myocardial infarction | 189 (3.43) | 235 (3.77) | 6 (0.07) | 0 | 247 (1.05) | 97 (0.18) | 801 (0.83) |
| Myocarditis | 35 (0.63) | 291 (4.67) | 69 (0.78) | 2 (1.37) | 1852 (7.84) | 590 (1.12) | 2877 (2.97) |
| Nasal congestion | 3 (0.05) | 6 (0.10) | 22 (0.25) | 0 | 53 (0.22) | 58 (0.11) | 144 (0.15) |
| Nasopharyngitis | 7 (0.13) | 10 (0.16) | 37 (0.42) | 0 | 61 (0.26) | 194 (0.37) | 311 (0.32) |
| Nausea | 99 (1.79) | 301 (4.83) | 1371 (15.59) | 5 (3.42) | 1364 (5.77) | 3799 (7.21) | 7014 (7.23) |
| Neck pain | 10 (0.18) | 44 (0.71) | 184 (2.09) | 2 (1.37) | 158 (0.67) | 361 (0.69) | 768 (0.79) |
| Nephrolithiasis | 1 (0.02) | 5 (0.08) | 5 (0.06) | 0 | 32 (0.14) | 56 (0.11) | 100 (0.10) |
| Nerve injury | 0 | 2 (0.03) | 35 (0.40) | 0 | 10 (0.04) | 16 (0.03) | 64 (0.07) |
| Nervous system disorder | 5 (0.09) | 3 (0.05) | 25 (0.28) | 0 | 26 (0.11) | 21 (0.04) | 84 (0.09) |
| Nervousness | 2 (0.04) | 1 (0.02) | 15 (0.17) | 0 | 13 (0.06) | 32 (0.06) | 67 (0.07) |
| Neuralgia | 1 (0.02) | 11 (0.18) | 104 (1.18) | 1 (0.68) | 53 (0.22) | 142 (0.27) | 315 (0.32) |
| Neuralgic amyotrophy | 1 (0.02) | 1 (0.02) | 29 (0.33) | 0 | 17 (0.07) | 19 (0.04) | 70 (0.07) |
| Neurological symptom | 6 (0.11) | 28 (0.45) | 41 (0.47) | 0 | 80 (0.34) | 10 (0.02) | 170 (0.18) |
| Neuropathy peripheral | 1 (0.02) | 5 (0.08) | 68 (0.77) | 0 | 37 (0.16) | 343 (0.65) | 467 (0.48) |
| Night sweats | 2 (0.04) | 16 (0.26) | 42 (0.48) | 0 | 46 (0.19) | 220 (0.42) | 330 (0.34) |
| Nightmare | 1 (0.02) | 3 (0.05) | 7 (0.08) | 1 (0.68) | 5 (0.02) | 36 (0.07) | 54 (0.06) |
| Ocular discomfort | 0 | 1 (0.02) | 13 (0.15) | 0 | 17 (0.07) | 20 (0.04) | 53 (0.05) |
| Ocular hyperaemia | 1 (0.02) | 8 (0.13) | 11 (0.13) | 1 (0.68) | 20 (0.08) | 33 (0.06) | 75 (0.08) |
| Oedema | 11 (0.20) | 12 (0.19) | 17 (0.19) | 0 | 59 (0.25) | 37 (0.07) | 143 (0.15) |
| Oedema peripheral | 11 (0.20) | 27 (0.43) | 39 (0.44) | 0 | 111 (0.47) | 86 (0.16) | 281 (0.29) |
| Off label use | 0 | 2 (0.03) | 4 (0.05) | 0 | 9 (0.04) | 51 (0.10) | 68 (0.07) |
| Ophthalmic herpes zoster | 0 | 1 (0.02) | 6 (0.07) | 1 (0.68) | 9 (0.04) | 72 (0.14) | 89 (0.09) |
| Optic neuritis | 0 | 2 (0.03) | 22 (0.25) | 0 | 30 (0.13) | 39 (0.07) | 94 (0.10) |
| Oral herpes | 1 (0.02) | 4 (0.06) | 16 (0.18) | 0 | 13 (0.06) | 67 (0.13) | 101 (0.10) |
| Oropharyngeal discomfort | 0 | 10 (0.16) | 3 (0.03) | 0 | 24 (0.10) | 18 (0.03) | 58 (0.06) |
| Oropharyngeal pain | 17 (0.31) | 38 (0.61) | 96 (1.09) | 0 | 171 (0.72) | 418 (0.79) | 746 (0.77) |
| Oxygen saturation decreased | 38 (0.69) | 36 (0.58) | 11 (0.13) | 0 | 120 (0.51) | 23 (0.04) | 247 (0.25) |
| Pain | 77 (1.40) | 259 (4.16) | 826 (9.39) | 6 (4.11) | 875 (3.70) | 1892 (3.59) | 3989 (4.11) |
| Pain in extremity | 49 (0.89) | 291 (4.67) | 925 (10.52) | 6 (4.11) | 655 (2.77) | 2774 (5.26) | 4742 (4.89) |
| Pain in jaw | 2 (0.04) | 13 (0.21) | 31 (0.35) | 0 | 42 (0.18) | 64 (0.12) | 156 (0.16) |
| Pain of skin | 0 | 6 (0.10) | 35 (0.40) | 0 | 8 (0.03) | 108 (0.20) | 159 (0.16) |
| Painful respiration | 3 (0.05) | 20 (0.32) | 6 (0.07) | 0 | 56 (0.24) | 7 (0.01) | 95 (0.10) |
| Pallor | 15 (0.27) | 17 (0.27) | 12 (0.14) | 1 (0.68) | 54 (0.23) | 55 (0.10) | 161 (0.17) |
| Palpitations | 11 (0.20) | 181 (2.91) | 330 (3.75) | 1 (0.68) | 589 (2.49) | 1222 (2.32) | 2357 (2.43) |
| Pancreatitis | 4 (0.07) | 13 (0.21) | 4 (0.05) | 0 | 56 (0.24) | 33 (0.06) | 111 (0.11) |
| Pancreatitis acute | 0 | 12 (0.19) | 0 | 0 | 65 (0.28) | 10 (0.02) | 90 (0.09) |
| Pancytopenia | 1 (0.02) | 10 (0.16) | 1 (0.01) | 0 | 29 (0.12) | 6 (0.01) | 53 (0.05) |
| Panic attack | 1 (0.02) | 6 (0.10) | 30 (0.34) | 0 | 16 (0.07) | 40 (0.08) | 96 (0.10) |
| Paraesthesia | 2 (0.04) | 122 (1.96) | 393 (4.47) | 0 | 523 (2.21) | 861 (1.63) | 1921 (1.98) |
| Paraesthesia oral | 0 | 30 (0.48) | 22 (0.25) | 0 | 59 (0.25) | 97 (0.18) | 210 (0.22) |
| Paralysis | 8 (0.14) | 29 (0.47) | 65 (0.74) | 1 (0.68) | 61 (0.26) | 163 (0.31) | 342 (0.35) |
| Parosmia | 1 (0.02) | 5 (0.08) | 33 (0.38) | 0 | 13 (0.06) | 25 (0.05) | 77 (0.08) |
| Pelvic pain | 0 | 3 (0.05) | 17 (0.19) | 1 (0.68) | 10 (0.04) | 21 (0.04) | 52 (0.05) |
| Pemphigoid | 2 (0.04) | 1 (0.02) | 6 (0.07) | 0 | 13 (0.06) | 30 (0.06) | 52 (0.05) |
| Periarthritis | 0 | 0 | 40 (0.45) | 0 | 4 (0.02) | 48 (0.09) | 92 (0.09) |
| Pericardial effusion | 6 (0.11) | 59 (0.95) | 8 (0.09) | 0 | 140 (0.59) | 78 (0.15) | 305 (0.31) |
| Pericarditis | 8 (0.14) | 128 (2.06) | 36 (0.41) | 0 | 633 (2.68) | 649 (1.23) | 1468 (1.51) |
| Peripheral coldness | 12 (0.22) | 20 (0.32) | 26 (0.30) | 0 | 31 (0.13) | 91 (0.17) | 183 (0.19) |
| Peripheral swelling | 24 (0.43) | 158 (2.54) | 265 (3.01) | 1 (0.68) | 290 (1.23) | 1085 (2.06) | 1855 (1.91) |
| Petechiae | 3 (0.05) | 34 (0.55) | 10 (0.11) | 0 | 85 (0.36) | 29 (0.06) | 166 (0.17) |
| Pharyngeal swelling | 0 | 89 (1.43) | 20 (0.23) | 0 | 60 (0.25) | 83 (0.16) | 258 (0.27) |
| Photophobia | 1 (0.02) | 9 (0.14) | 58 (0.66) | 0 | 39 (0.17) | 130 (0.25) | 240 (0.25) |
| Platelet count decreased | 9 (0.16) | 38 (0.61) | 3 (0.03) | 1 (0.68) | 52 (0.22) | 11 (0.02) | 120 (0.12) |
| Pleural effusion | 29 (0.53) | 44 (0.71) | 12 (0.14) | 0 | 162 (0.69) | 8 (0.02) | 274 (0.28) |
| Pleuritic pain | 0 | 16 (0.26) | 1 (0.01) | 0 | 55 (0.23) | 2 (0.00) | 79 (0.08) |
| Pneumonia | 166 (3.01) | 117 (1.88) | 19 (0.22) | 0 | 611 (2.59) | 252 (0.48) | 1235 (1.27) |
| Pneumonia aspiration | 20 (0.36) | 11 (0.18) | 1 (0.01) | 0 | 22 (0.09) | 2 (0.00) | 60 (0.06) |
| Pneumonia bacterial | 14 (0.25) | 1 (0.02) | 1 (0.01) | 0 | 35 (0.15) | 8 (0.02) | 60 (0.06) |
| Pneumonitis | 5 (0.09) | 13 (0.21) | 1 (0.01) | 0 | 40 (0.17) | 9 (0.02) | 70 (0.07) |
| Pneumothorax | 9 (0.16) | 6 (0.10) | 1 (0.01) | 0 | 29 (0.12) | 10 (0.02) | 59 (0.06) |
| Pollakiuria | 4 (0.07) | 5 (0.08) | 20 (0.23) | 0 | 26 (0.11) | 35 (0.07) | 91 (0.09) |
| Polymenorrhoea | 0 | 0 | 37 (0.42) | 2 (1.37) | 9 (0.04) | 94 (0.18) | 142 (0.15) |
| Polymyalgia rheumatica | 0 | 1 (0.02) | 20 (0.23) | 0 | 11 (0.05) | 112 (0.21) | 144 (0.15) |
| Polyneuropathy | 0 | 3 (0.05) | 11 (0.13) | 0 | 22 (0.09) | 19 (0.04) | 57 (0.06) |
| Poor quality sleep | 3 (0.05) | 0 | 21 (0.24) | 0 | 6 (0.03) | 69 (0.13) | 100 (0.10) |
| Portal vein thrombosis | 4 (0.07) | 10 (0.16) | 0 | 0 | 36 (0.15) | 3 (0.01) | 53 (0.05) |
| Positive airway pressure therapy | 27 (0.49) | 3 (0.05) | 1 (0.01) | 0 | 30 (0.13) | 0 | 61 (0.06) |
| Postmenopausal haemorrhage | 0 | 0 | 5 (0.06) | 0 | 3 (0.01) | 225 (0.43) | 233 (0.24) |
| Presyncope | 1 (0.02) | 26 (0.42) | 49 (0.56) | 2 (1.37) | 178 (0.75) | 223 (0.42) | 489 (0.50) |
| Productive cough | 22 (0.40) | 11 (0.18) | 17 (0.19) | 0 | 119 (0.50) | 22 (0.04) | 197 (0.20) |
| Pruritus | 7 (0.13) | 112 (1.80) | 153 (1.74) | 3 (2.05) | 238 (1.01) | 974 (1.85) | 1497 (1.54) |
| Psoriasis | 1 (0.02) | 2 (0.03) | 10 (0.11) | 0 | 7 (0.03) | 31 (0.06) | 51 (0.05) |
| Pulmonary congestion | 4 (0.07) | 9 (0.14) | 3 (0.03) | 0 | 36 (0.15) | 96 (0.18) | 155 (0.16) |
| Pulmonary embolism | 122 (2.21) | 773 (12.41) | 26 (0.30) | 0 | 961 (4.07) | 271 (0.51) | 2176 (2.24) |
| Pulmonary fibrosis | 5 (0.09) | 2 (0.03) | 4 (0.05) | 0 | 28 (0.12) | 10 (0.02) | 53 (0.05) |
| Pulmonary hypertension | 4 (0.07) | 12 (0.19) | 1 (0.01) | 0 | 23 (0.10) | 12 (0.02) | 56 (0.06) |
| Pulmonary infarction | 3 (0.05) | 31 (0.50) | 1 (0.01) | 0 | 28 (0.12) | 9 (0.02) | 74 (0.08) |
| Pulmonary mass | 9 (0.16) | 11 (0.18) | 8 (0.09) | 0 | 43 (0.18) | 4 (0.01) | 79 (0.08) |
| Pulmonary oedema | 38 (0.69) | 41 (0.66) | 5 (0.06) | 1 (0.68) | 99 (0.42) | 20 (0.04) | 226 (0.23) |
| Pulmonary pain | 0 | 14 (0.22) | 16 (0.18) | 0 | 17 (0.07) | 26 (0.05) | 73 (0.08) |
| Pulmonary thrombosis | 15 (0.27) | 109 (1.75) | 11 (0.13) | 0 | 97 (0.41) | 20 (0.04) | 257 (0.26) |
| Pulseless electrical activity | 33 (0.60) | 11 (0.18) | 0 | 0 | 4 (0.02) | 0 | 54 (0.06) |
| Purpura | 0 | 7 (0.11) | 5 (0.06) | 0 | 25 (0.11) | 18 (0.03) | 55 (0.06) |
| Pyrexia | 282 (5.11) | 527 (8.46) | 2111 (24.01) | 17 (11.64) | 2906 (12.30) | 6366 (12.08) | 12371 (12.75) |
| Rash | 12 (0.22) | 129 (2.07) | 228 (2.59) | 1 (0.68) | 445 (1.88) | 1213 (2.30) | 2045 (2.11) |
| Rash erythematous | 2 (0.04) | 21 (0.34) | 34 (0.39) | 0 | 60 (0.25) | 337 (0.64) | 459 (0.47) |
| Rash macular | 2 (0.04) | 8 (0.13) | 32 (0.36) | 0 | 22 (0.09) | 81 (0.15) | 146 (0.15) |
| Rash papular | 0 | 5 (0.08) | 5 (0.06) | 0 | 11 (0.05) | 80 (0.15) | 102 (0.11) |
| Rash pruritic | 1 (0.02) | 12 (0.19) | 34 (0.39) | 0 | 51 (0.22) | 213 (0.40) | 311 (0.32) |
| Rectal haemorrhage | 3 (0.05) | 3 (0.05) | 3 (0.03) | 0 | 38 (0.16) | 65 (0.12) | 117 (0.12) |
| Renal failure | 61 (1.11) | 36 (0.58) | 6 (0.07) | 0 | 59 (0.25) | 18 (0.03) | 201 (0.21) |
| Renal impairment | 17 (0.31) | 9 (0.14) | 6 (0.07) | 0 | 36 (0.15) | 42 (0.08) | 119 (0.12) |
| Renal pain | 2 (0.04) | 1 (0.02) | 30 (0.34) | 0 | 18 (0.08) | 91 (0.17) | 142 (0.15) |
| Respiration abnormal | 8 (0.14) | 7 (0.11) | 6 (0.07) | 0 | 26 (0.11) | 15 (0.03) | 66 (0.07) |
| Respiratory arrest | 81 (1.47) | 25 (0.40) | 1 (0.01) | 0 | 16 (0.07) | 18 (0.03) | 155 (0.16) |
| Respiratory disorder | 14 (0.25) | 10 (0.16) | 13 (0.15) | 0 | 24 (0.10) | 8 (0.02) | 72 (0.07) |
| Respiratory distress | 39 (0.71) | 32 (0.51) | 6 (0.07) | 0 | 75 (0.32) | 59 (0.11) | 226 (0.23) |
| Respiratory failure | 126 (2.28) | 50 (0.80) | 7 (0.08) | 0 | 116 (0.49) | 6 (0.01) | 317 (0.33) |
| Respiratory tract congestion | 16 (0.29) | 4 (0.06) | 11 (0.13) | 0 | 110 (0.47) | 2 (0.00) | 149 (0.15) |
| Restlessness | 6 (0.11) | 7 (0.11) | 10 (0.11) | 0 | 19 (0.08) | 61 (0.12) | 104 (0.11) |
| Resuscitation | 45 (0.82) | 11 (0.18) | 0 | 0 | 11 (0.05) | 0 | 69 (0.07) |
| Retching | 1 (0.02) | 14 (0.22) | 17 (0.19) | 0 | 39 (0.17) | 32 (0.06) | 104 (0.11) |
| Retinal detachment | 0 | 0 | 11 (0.13) | 0 | 18 (0.08) | 23 (0.04) | 53 (0.05) |
| Retinal vein occlusion | 0 | 2 (0.03) | 28 (0.32) | 0 | 5 (0.02) | 36 (0.07) | 71 (0.07) |
| Rhabdomyolysis | 5 (0.09) | 22 (0.35) | 6 (0.07) | 0 | 62 (0.26) | 24 (0.05) | 124 (0.13) |
| Rheumatoid arthritis | 5 (0.09) | 2 (0.03) | 43 (0.49) | 0 | 19 (0.08) | 214 (0.41) | 286 (0.29) |
| Rhinorrhoea | 13 (0.24) | 4 (0.06) | 27 (0.31) | 0 | 80 (0.34) | 125 (0.24) | 252 (0.26) |
| SARS-CoV-2 test negative | 8 (0.14) | 11 (0.18) | 7 (0.08) | 0 | 42 (0.18) | 4 (0.01) | 73 (0.08) |
| SARS-CoV-2 test positive | 155 (2.81) | 13 (0.21) | 6 (0.07) | 0 | 930 (3.94) | 45 (0.09) | 1152 (1.19) |
| Seizure | 43 (0.78) | 118 (1.89) | 67 (0.76) | 3 (2.05) | 387 (1.64) | 1279 (2.43) | 1945 (2.01) |
| Seizure like phenomena | 5 (0.09) | 7 (0.11) | 5 (0.06) | 0 | 27 (0.11) | 64 (0.12) | 110 (0.11) |
| Sensation of foreign body | 1 (0.02) | 8 (0.13) | 6 (0.07) | 0 | 27 (0.11) | 9 (0.02) | 52 (0.05) |
| Sensitive skin | 0 | 1 (0.02) | 20 (0.23) | 0 | 6 (0.03) | 92 (0.17) | 121 (0.12) |
| Sensory disturbance | 0 | 4 (0.06) | 28 (0.32) | 0 | 39 (0.17) | 19 (0.04) | 92 (0.09) |
| Sensory loss | 1 (0.02) | 11 (0.18) | 31 (0.35) | 0 | 29 (0.12) | 21 (0.04) | 95 (0.10) |
| Sepsis | 98 (1.78) | 57 (0.92) | 6 (0.07) | 0 | 221 (0.94) | 17 (0.03) | 412 (0.42) |
| Septic shock | 61 (1.11) | 26 (0.42) | 0 | 0 | 30 (0.13) | 2 (0.00) | 122 (0.13) |
| Shock | 27 (0.49) | 17 (0.27) | 1 (0.01) | 0 | 13 (0.06) | 23 (0.04) | 88 (0.09) |
| Sinus headache | 0 | 0 | 4 (0.05) | 0 | 1 (0.00) | 72 (0.14) | 77 (0.08) |
| Sinus pain | 0 | 0 | 12 (0.14) | 1 (0.68) | 2 (0.01) | 57 (0.11) | 72 (0.07) |
| Sinus tachycardia | 5 (0.09) | 13 (0.21) | 10 (0.11) | 0 | 75 (0.32) | 10 (0.02) | 117 (0.12) |
| Sinusitis | 2 (0.04) | 1 (0.02) | 14 (0.16) | 0 | 21 (0.09) | 30 (0.06) | 69 (0.07) |
| Skin burning sensation | 0 | 7 (0.11) | 27 (0.31) | 0 | 23 (0.10) | 47 (0.09) | 107 (0.11) |
| Skin discolouration | 5 (0.09) | 29 (0.47) | 34 (0.39) | 1 (0.68) | 32 (0.14) | 28 (0.05) | 138 (0.14) |
| Skin disorder | 0 | 1 (0.02) | 134 (1.52) | 0 | 7 (0.03) | 18 (0.03) | 160 (0.16) |
| Skin exfoliation | 3 (0.05) | 6 (0.10) | 10 (0.11) | 0 | 18 (0.08) | 19 (0.04) | 56 (0.06) |
| Skin reaction | 1 (0.02) | 7 (0.11) | 10 (0.11) | 0 | 14 (0.06) | 83 (0.16) | 115 (0.12) |
| Skin warm | 4 (0.07) | 25 (0.40) | 23 (0.26) | 0 | 44 (0.19) | 89 (0.17) | 185 (0.19) |
| Sleep disorder | 2 (0.04) | 41 (0.66) | 125 (1.42) | 0 | 97 (0.41) | 90 (0.17) | 364 (0.38) |
| Sneezing | 1 (0.02) | 3 (0.05) | 10 (0.11) | 0 | 7 (0.03) | 34 (0.06) | 55 (0.06) |
| Somnolence | 29 (0.53) | 32 (0.51) | 82 (0.93) | 2 (1.37) | 130 (0.55) | 250 (0.47) | 551 (0.57) |
| Speech disorder | 9 (0.16) | 46 (0.74) | 63 (0.72) | 1 (0.68) | 139 (0.59) | 35 (0.07) | 303 (0.31) |
| Spinal pain | 0 | 2 (0.03) | 24 (0.27) | 0 | 8 (0.03) | 23 (0.04) | 59 (0.06) |
| Staphylococcal infection | 8 (0.14) | 7 (0.11) | 2 (0.02) | 0 | 19 (0.08) | 23 (0.04) | 59 (0.06) |
| Status epilepticus | 1 (0.02) | 11 (0.18) | 3 (0.03) | 0 | 19 (0.08) | 31 (0.06) | 66 (0.07) |
| Subarachnoid haemorrhage | 15 (0.27) | 39 (0.63) | 2 (0.02) | 0 | 38 (0.16) | 0 | 95 (0.10) |
| Subdural haematoma | 11 (0.20) | 12 (0.19) | 2 (0.02) | 0 | 19 (0.08) | 5 (0.01) | 52 (0.05) |
| Sudden death | 157 (2.85) | 0 | 0 | 0 | 0 | 0 | 157 (0.16) |
| Sudden hearing loss | 0 | 3 (0.05) | 64 (0.73) | 0 | 14 (0.06) | 111 (0.21) | 192 (0.20) |
| Suicidal ideation | 1 (0.02) | 17 (0.27) | 12 (0.14) | 0 | 12 (0.05) | 84 (0.16) | 130 (0.13) |
| Superficial vein thrombosis | 1 (0.02) | 9 (0.14) | 2 (0.02) | 0 | 16 (0.07) | 57 (0.11) | 87 (0.09) |
| Supraventricular tachycardia | 6 (0.11) | 28 (0.45) | 13 (0.15) | 0 | 53 (0.22) | 18 (0.03) | 121 (0.12) |
| Sweating fever | 0 | 0 | 3 (0.03) | 0 | 1 (0.00) | 49 (0.09) | 53 (0.05) |
| Swelling | 11 (0.20) | 35 (0.56) | 113 (1.29) | 0 | 120 (0.51) | 570 (1.08) | 854 (0.88) |
| Swelling face | 3 (0.05) | 67 (1.08) | 45 (0.51) | 0 | 117 (0.50) | 183 (0.35) | 427 (0.44) |
| Swollen tongue | 2 (0.04) | 87 (1.40) | 18 (0.20) | 0 | 103 (0.44) | 87 (0.17) | 303 (0.31) |
| Syncope | 82 (1.49) | 200 (3.21) | 149 (1.69) | 4 (2.74) | 672 (2.84) | 4284 (8.13) | 5488 (5.66) |
| Systemic inflammatory response syndrome | 6 (0.11) | 13 (0.21) | 1 (0.01) | 0 | 41 (0.17) | 18 (0.03) | 82 (0.08) |
| Systemic lupus erythematosus | 1 (0.02) | 9 (0.14) | 11 (0.13) | 0 | 13 (0.06) | 57 (0.11) | 93 (0.10) |
| Tachycardia | 28 (0.51) | 164 (2.63) | 151 (1.72) | 2 (1.37) | 567 (2.40) | 700 (1.33) | 1629 (1.68) |
| Tachypnoea | 13 (0.24) | 14 (0.22) | 1 (0.01) | 0 | 93 (0.39) | 7 (0.01) | 133 (0.14) |
| Taste disorder | 3 (0.05) | 9 (0.14) | 35 (0.40) | 0 | 27 (0.11) | 35 (0.07) | 113 (0.12) |
| Tenderness | 2 (0.04) | 7 (0.11) | 31 (0.35) | 0 | 31 (0.13) | 95 (0.18) | 168 (0.17) |
| Tension headache | 0 | 3 (0.05) | 22 (0.25) | 0 | 11 (0.05) | 116 (0.22) | 152 (0.16) |
| Thirst | 0 | 6 (0.10) | 18 (0.20) | 0 | 19 (0.08) | 77 (0.15) | 123 (0.13) |
| Throat irritation | 0 | 29 (0.47) | 8 (0.09) | 0 | 48 (0.20) | 56 (0.11) | 142 (0.15) |
| Throat tightness | 2 (0.04) | 94 (1.51) | 19 (0.22) | 0 | 79 (0.33) | 75 (0.14) | 275 (0.28) |
| Thrombocytopenia | 30 (0.54) | 92 (1.48) | 6 (0.07) | 0 | 235 (0.99) | 146 (0.28) | 533 (0.55) |
| Thrombophlebitis | 0 | 7 (0.11) | 1 (0.01) | 0 | 12 (0.05) | 36 (0.07) | 56 (0.06) |
| Thrombosis | 60 (1.09) | 244 (3.92) | 51 (0.58) | 2 (1.37) | 286 (1.21) | 761 (1.44) | 1445 (1.49) |
| Tinnitus | 1 (0.02) | 33 (0.53) | 535 (6.08) | 1 (0.68) | 82 (0.35) | 334 (0.63) | 996 (1.03) |
| Toothache | 1 (0.02) | 6 (0.10) | 10 (0.11) | 0 | 6 (0.03) | 30 (0.06) | 55 (0.06) |
| Transient ischaemic attack | 8 (0.14) | 60 (0.96) | 20 (0.23) | 0 | 177 (0.75) | 118 (0.22) | 394 (0.41) |
| Tremor | 19 (0.34) | 100 (1.61) | 223 (2.54) | 0 | 283 (1.20) | 566 (1.07) | 1212 (1.25) |
| Troponin increased | 8 (0.14) | 31 (0.50) | 2 (0.02) | 0 | 123 (0.52) | 9 (0.02) | 178 (0.18) |
| Tunnel vision | 0 | 1 (0.02) | 8 (0.09) | 0 | 1 (0.00) | 88 (0.17) | 100 (0.10) |
| Unevaluable event | 4 (0.07) | 13 (0.21) | 7 (0.08) | 1 (0.68) | 439 (1.86) | 2 (0.00) | 467 (0.48) |
| Unresponsive to stimuli | 188 (3.41) | 64 (1.03) | 8 (0.09) | 0 | 129 (0.55) | 533 (1.01) | 994 (1.02) |
| Urinary incontinence | 3 (0.05) | 12 (0.19) | 20 (0.23) | 0 | 46 (0.19) | 18 (0.03) | 106 (0.11) |
| Urinary retention | 5 (0.09) | 9 (0.14) | 8 (0.09) | 0 | 40 (0.17) | 41 (0.08) | 105 (0.11) |
| Urinary tract infection | 41 (0.74) | 27 (0.43) | 17 (0.19) | 0 | 202 (0.86) | 60 (0.11) | 368 (0.38) |
| Urticaria | 0 | 101 (1.62) | 85 (0.97) | 2 (1.37) | 222 (0.94) | 534 (1.01) | 955 (0.98) |
| Uveitis | 0 | 0 | 10 (0.11) | 0 | 2 (0.01) | 53 (0.10) | 66 (0.07) |
| Vaccination complication | 17 (0.31) | 39 (0.63) | 42 (0.48) | 0 | 197 (0.83) | 84 (0.16) | 391 (0.40) |
| Vaccination failure | 26 (0.47) | 20 (0.32) | 1 (0.01) | 0 | 108 (0.46) | 3195 (6.06) | 3358 (3.46) |
| Vaccination site erythema | 0 | 10 (0.16) | 98 (1.11) | 0 | 64 (0.27) | 239 (0.45) | 416 (0.43) |
| Vaccination site inflammation | 0 | 0 | 8 (0.09) | 0 | 6 (0.03) | 50 (0.09) | 64 (0.07) |
| Vaccination site movement impairment | 0 | 1 (0.02) | 26 (0.30) | 0 | 8 (0.03) | 27 (0.05) | 64 (0.07) |
| Vaccination site oedema | 0 | 2 (0.03) | 40 (0.45) | 0 | 10 (0.04) | 67 (0.13) | 119 (0.12) |
| Vaccination site pain | 10 (0.18) | 33 (0.53) | 245 (2.79) | 0 | 141 (0.60) | 490 (0.93) | 928 (0.96) |
| Vaccination site pruritus | 0 | 5 (0.08) | 45 (0.51) | 0 | 17 (0.07) | 106 (0.20) | 173 (0.18) |
| Vaccination site rash | 0 | 0 | 11 (0.13) | 0 | 10 (0.04) | 87 (0.17) | 108 (0.11) |
| Vaccination site reaction | 0 | 6 (0.10) | 12 (0.14) | 0 | 29 (0.12) | 73 (0.14) | 121 (0.12) |
| Vaccination site swelling | 2 (0.04) | 8 (0.13) | 57 (0.65) | 0 | 59 (0.25) | 184 (0.35) | 316 (0.33) |
| Vaccination site warmth | 0 | 2 (0.03) | 30 (0.34) | 0 | 19 (0.08) | 107 (0.20) | 158 (0.16) |
| Vaccine breakthrough infection | 42 (0.76) | 1 (0.02) | 2 (0.02) | 0 | 318 (1.35) | 89 (0.17) | 468 (0.48) |
| Vaginal haemorrhage | 1 (0.02) | 17 (0.27) | 13 (0.15) | 6 (4.11) | 40 (0.17) | 158 (0.30) | 235 (0.24) |
| Vasculitis | 3 (0.05) | 10 (0.16) | 3 (0.03) | 0 | 29 (0.12) | 20 (0.04) | 71 (0.07) |
| Venous thrombosis | 1 (0.02) | 15 (0.24) | 3 (0.03) | 0 | 17 (0.07) | 25 (0.05) | 66 (0.07) |
| Venous thrombosis limb | 1 (0.02) | 9 (0.14) | 6 (0.07) | 0 | 22 (0.09) | 54 (0.10) | 93 (0.10) |
| Ventricular extrasystoles | 1 (0.02) | 6 (0.10) | 15 (0.17) | 0 | 45 (0.19) | 30 (0.06) | 100 (0.10) |
| Ventricular fibrillation | 24 (0.43) | 29 (0.47) | 1 (0.01) | 0 | 15 (0.06) | 1 (0.00) | 79 (0.08) |
| Ventricular hypokinesia | 1 (0.02) | 16 (0.26) | 3 (0.03) | 0 | 32 (0.14) | 3 (0.01) | 57 (0.06) |
| Ventricular tachycardia | 15 (0.27) | 37 (0.59) | 2 (0.02) | 0 | 48 (0.20) | 21 (0.04) | 128 (0.13) |
| Vertigo | 3 (0.05) | 37 (0.59) | 229 (2.60) | 0 | 205 (0.87) | 333 (0.63) | 819 (0.84) |
| Vestibular neuronitis | 0 | 2 (0.03) | 14 (0.16) | 0 | 48 (0.20) | 18 (0.03) | 83 (0.09) |
| Vision blurred | 7 (0.13) | 37 (0.59) | 171 (1.94) | 2 (1.37) | 162 (0.69) | 266 (0.50) | 652 (0.67) |
| Visual field defect | 0 | 5 (0.08) | 22 (0.25) | 0 | 23 (0.10) | 11 (0.02) | 64 (0.07) |
| Visual impairment | 3 (0.05) | 32 (0.51) | 151 (1.72) | 0 | 153 (0.65) | 111 (0.21) | 463 (0.48) |
| Vomiting | 133 (2.41) | 255 (4.09) | 423 (4.81) | 2 (1.37) | 1136 (4.81) | 1620 (3.07) | 3658 (3.77) |
| Walking aid user | 7 (0.13) | 12 (0.19) | 38 (0.43) | 0 | 27 (0.11) | 1 (0.00) | 88 (0.09) |
| Weight decreased | 9 (0.16) | 21 (0.34) | 41 (0.47) | 0 | 68 (0.29) | 39 (0.07) | 184 (0.19) |
| Weight increased | 2 (0.04) | 4 (0.06) | 13 (0.15) | 0 | 20 (0.08) | 11 (0.02) | 51 (0.05) |
| Wheezing | 12 (0.22) | 42 (0.67) | 16 (0.18) | 0 | 104 (0.44) | 92 (0.17) | 276 (0.28) |
| White blood cell count increased | 9 (0.16) | 13 (0.21) | 6 (0.07) | 0 | 57 (0.24) | 1 (0.00) | 89 (0.09) |
| X-ray | 2 (0.04) | 16 (0.26) | 23 (0.26) | 0 | 10 (0.04) | 1 (0.00) | 52 (0.05) |