Eudravigilance C-19 - Moderna

Liste des effets indésirables (uniquement ceux qui apparaissent dans plus de 50 cas graves)

PT

Décès

5518 (%)

Mise en jeu du pronostic vital

6228 (%)

Invalidité ou incapacité

8793 (%)

Anomalies congénitales

146 (%)

Hospitalisation

23622 (%)

Médicalement significatif

52691 (%)

Cas Graves

96998 (%)

Abdominal discomfort 14 (0.25) 20 (0.32) 41 (0.47) 1 (0.68) 74 (0.31) 116 (0.22) 274 (0.28)
Abdominal distension 12 (0.22) 16 (0.26) 11 (0.13) 0 54 (0.23) 54 (0.10) 149 (0.15)
Abdominal pain 38 (0.69) 91 (1.46) 113 (1.29) 5 (3.42) 474 (2.01) 350 (0.66) 1095 (1.13)
Abdominal pain lower 2 (0.04) 19 (0.31) 11 (0.13) 0 67 (0.28) 31 (0.06) 132 (0.14)
Abdominal pain upper 32 (0.58) 59 (0.95) 105 (1.19) 0 248 (1.05) 622 (1.18) 1071 (1.10)
Abnormal behaviour 4 (0.07) 7 (0.11) 6 (0.07) 0 37 (0.16) 7 (0.01) 65 (0.07)
Abortion spontaneous 0 9 (0.14) 18 (0.20) 48 (32.88) 39 (0.17) 360 (0.68) 478 (0.49)
Acute coronary syndrome 5 (0.09) 14 (0.22) 0 0 43 (0.18) 2 (0.00) 65 (0.07)
Acute kidney injury 97 (1.76) 70 (1.12) 10 (0.11) 0 307 (1.30) 29 (0.06) 554 (0.57)
Acute myocardial infarction 68 (1.23) 133 (2.14) 6 (0.07) 0 222 (0.94) 13 (0.02) 455 (0.47)
Acute respiratory distress syndrome 31 (0.56) 14 (0.22) 1 (0.01) 0 25 (0.11) 4 (0.01) 83 (0.09)
Acute respiratory failure 131 (2.37) 50 (0.80) 3 (0.03) 0 311 (1.32) 3 (0.01) 509 (0.52)
Adverse drug reaction 0 3 (0.05) 18 (0.20) 0 12 (0.05) 76 (0.14) 110 (0.11)
Ageusia 9 (0.16) 12 (0.19) 56 (0.64) 1 (0.68) 81 (0.34) 79 (0.15) 242 (0.25)
Aggression 4 (0.07) 8 (0.13) 6 (0.07) 0 30 (0.13) 3 (0.01) 52 (0.05)
Agitation 10 (0.18) 7 (0.11) 8 (0.09) 0 32 (0.14) 19 (0.04) 81 (0.08)
Alopecia 0 5 (0.08) 36 (0.41) 1 (0.68) 19 (0.08) 51 (0.10) 113 (0.12)
Altered state of consciousness 26 (0.47) 13 (0.21) 8 (0.09) 0 74 (0.31) 80 (0.15) 214 (0.22)
Amenorrhoea 0 2 (0.03) 54 (0.61) 1 (0.68) 7 (0.03) 86 (0.16) 150 (0.15)
Amnesia 6 (0.11) 32 (0.51) 61 (0.69) 0 80 (0.34) 61 (0.12) 248 (0.26)
Anaemia 17 (0.31) 33 (0.53) 13 (0.15) 0 114 (0.48) 22 (0.04) 213 (0.22)
Anaphylactic reaction 2 (0.04) 236 (3.79) 11 (0.13) 0 314 (1.33) 870 (1.65) 1453 (1.50)
Anaphylactic shock 3 (0.05) 57 (0.92) 1 (0.01) 0 59 (0.25) 60 (0.11) 185 (0.19)
Anaphylactoid reaction 0 4 (0.06) 0 0 21 (0.09) 42 (0.08) 70 (0.07)
Angina pectoris 7 (0.13) 21 (0.34) 27 (0.31) 0 101 (0.43) 246 (0.47) 408 (0.42)
Angioedema 0 41 (0.66) 10 (0.11) 0 66 (0.28) 478 (0.91) 606 (0.62)
Anosmia 7 (0.13) 8 (0.13) 39 (0.44) 0 61 (0.26) 47 (0.09) 166 (0.17)
Anticoagulant therapy 10 (0.18) 93 (1.49) 12 (0.14) 0 100 (0.42) 0 216 (0.22)
Anxiety 6 (0.11) 32 (0.51) 112 (1.27) 1 (0.68) 124 (0.52) 141 (0.27) 425 (0.44)
Aphasia 18 (0.33) 88 (1.41) 73 (0.83) 0 209 (0.88) 22 (0.04) 428 (0.44)
Appendicitis 0 59 (0.95) 1 (0.01) 0 142 (0.60) 38 (0.07) 242 (0.25)
Arrhythmia 25 (0.45) 55 (0.88) 50 (0.57) 0 210 (0.89) 419 (0.80) 771 (0.79)
Arthralgia 25 (0.45) 138 (2.22) 1469 (16.71) 1 (0.68) 492 (2.08) 2236 (4.24) 4388 (4.52)
Arthritis 2 (0.04) 6 (0.10) 61 (0.69) 0 29 (0.12) 56 (0.11) 154 (0.16)
Ascites 11 (0.20) 6 (0.10) 2 (0.02) 0 20 (0.08) 8 (0.02) 54 (0.06)
Aspiration 12 (0.22) 11 (0.18) 0 0 16 (0.07) 7 (0.01) 54 (0.06)
Asthenia 205 (3.72) 306 (4.91) 480 (5.46) 1 (0.68) 1433 (6.07) 839 (1.59) 3383 (3.49)
Asthma 11 (0.20) 45 (0.72) 21 (0.24) 0 91 (0.39) 104 (0.20) 274 (0.28)
Asymptomatic COVID-19 5 (0.09) 1 (0.02) 0 0 97 (0.41) 10 (0.02) 113 (0.12)
Ataxia 1 (0.02) 5 (0.08) 9 (0.10) 0 29 (0.12) 6 (0.01) 56 (0.06)
Atelectasis 13 (0.24) 16 (0.26) 3 (0.03) 0 105 (0.44) 0 140 (0.14)
Atrial fibrillation 57 (1.03) 170 (2.73) 45 (0.51) 0 493 (2.09) 548 (1.04) 1352 (1.39)
Atrial flutter 1 (0.02) 15 (0.24) 4 (0.05) 0 47 (0.20) 19 (0.04) 91 (0.09)
Atrioventricular block 3 (0.05) 19 (0.31) 1 (0.01) 0 20 (0.08) 7 (0.01) 52 (0.05)
Autoimmune disorder 2 (0.04) 8 (0.13) 25 (0.28) 0 22 (0.09) 76 (0.14) 143 (0.15)
Axillary mass 0 1 (0.02) 16 (0.18) 0 5 (0.02) 34 (0.06) 56 (0.06)
Axillary pain 1 (0.02) 9 (0.14) 107 (1.22) 0 31 (0.13) 499 (0.95) 649 (0.67)
Back pain 41 (0.74) 90 (1.45) 249 (2.83) 4 (2.74) 288 (1.22) 644 (1.22) 1341 (1.38)
Balance disorder 10 (0.18) 33 (0.53) 127 (1.44) 0 150 (0.64) 123 (0.23) 454 (0.47)
Basedow's disease 0 4 (0.06) 12 (0.14) 0 7 (0.03) 27 (0.05) 51 (0.05)
Bedridden 7 (0.13) 9 (0.14) 17 (0.19) 0 9 (0.04) 28 (0.05) 71 (0.07)
Bell's palsy 0 7 (0.11) 125 (1.42) 1 (0.68) 104 (0.44) 1316 (2.50) 1561 (1.61)
Blindness 3 (0.05) 16 (0.26) 71 (0.81) 0 47 (0.20) 209 (0.40) 355 (0.37)
Blindness transient 0 0 6 (0.07) 0 10 (0.04) 50 (0.09) 69 (0.07)
Blindness unilateral 1 (0.02) 10 (0.16) 72 (0.82) 0 24 (0.10) 49 (0.09) 163 (0.17)
Blister 2 (0.04) 13 (0.21) 34 (0.39) 0 39 (0.17) 73 (0.14) 163 (0.17)
Blood creatinine increased 18 (0.33) 10 (0.16) 2 (0.02) 0 58 (0.25) 2 (0.00) 93 (0.10)
Blood glucose increased 11 (0.20) 7 (0.11) 6 (0.07) 0 55 (0.23) 14 (0.03) 97 (0.10)
Blood glucose normal 8 (0.14) 7 (0.11) 2 (0.02) 0 36 (0.15) 0 53 (0.05)
Blood pressure decreased 6 (0.11) 16 (0.26) 18 (0.20) 0 60 (0.25) 48 (0.09) 152 (0.16)
Blood pressure fluctuation 1 (0.02) 12 (0.19) 10 (0.11) 0 24 (0.10) 6 (0.01) 54 (0.06)
Blood pressure increased 5 (0.09) 49 (0.79) 38 (0.43) 1 (0.68) 176 (0.75) 99 (0.19) 382 (0.39)
Blood test 2 (0.04) 57 (0.92) 60 (0.68) 0 78 (0.33) 0 197 (0.20)
Blood urea increased 14 (0.25) 2 (0.03) 0 0 34 (0.14) 0 52 (0.05)
Body temperature 0 1 (0.02) 8 (0.09) 0 2 (0.01) 51 (0.10) 62 (0.06)
Body temperature increased 8 (0.14) 10 (0.16) 21 (0.24) 0 66 (0.28) 81 (0.15) 190 (0.20)
Bone pain 2 (0.04) 16 (0.26) 45 (0.51) 0 22 (0.09) 106 (0.20) 193 (0.20)
Bradycardia 20 (0.36) 34 (0.55) 8 (0.09) 1 (0.68) 73 (0.31) 215 (0.41) 362 (0.37)
Brain oedema 10 (0.18) 18 (0.29) 5 (0.06) 0 17 (0.07) 14 (0.03) 67 (0.07)
Breast pain 2 (0.04) 12 (0.19) 32 (0.36) 0 29 (0.12) 87 (0.17) 163 (0.17)
Bronchitis 3 (0.05) 7 (0.11) 5 (0.06) 0 41 (0.17) 19 (0.04) 76 (0.08)
Burning sensation 2 (0.04) 32 (0.51) 112 (1.27) 2 (1.37) 52 (0.22) 121 (0.23) 326 (0.34)
Bursitis 0 0 23 (0.26) 0 9 (0.04) 28 (0.05) 61 (0.06)
C-reactive protein increased 6 (0.11) 10 (0.16) 11 (0.13) 0 110 (0.47) 15 (0.03) 154 (0.16)
COVID-19 656 (11.89) 112 (1.80) 51 (0.58) 1 (0.68) 3074 (13.01) 3500 (6.64) 7470 (7.70)
COVID-19 immunisation 3 (0.05) 32 (0.51) 355 (4.04) 0 83 (0.35) 64 (0.12) 538 (0.55)
COVID-19 pneumonia 184 (3.33) 23 (0.37) 5 (0.06) 0 570 (2.41) 52 (0.10) 857 (0.88)
Cardiac arrest 401 (7.27) 108 (1.73) 3 (0.03) 0 40 (0.17) 11 (0.02) 584 (0.60)
Cardiac discomfort 3 (0.05) 7 (0.11) 7 (0.08) 0 20 (0.08) 17 (0.03) 57 (0.06)
Cardiac disorder 19 (0.34) 31 (0.50) 16 (0.18) 0 57 (0.24) 21 (0.04) 153 (0.16)
Cardiac failure 75 (1.36) 52 (0.83) 13 (0.15) 0 122 (0.52) 34 (0.06) 312 (0.32)
Cardiac failure acute 19 (0.34) 7 (0.11) 0 0 38 (0.16) 0 66 (0.07)
Cardiac failure congestive 39 (0.71) 47 (0.75) 10 (0.11) 0 139 (0.59) 28 (0.05) 273 (0.28)
Cardiac flutter 1 (0.02) 13 (0.21) 17 (0.19) 0 31 (0.13) 405 (0.77) 471 (0.49)
Cardio-respiratory arrest 125 (2.27) 28 (0.45) 0 0 12 (0.05) 8 (0.02) 183 (0.19)
Cardiogenic shock 37 (0.67) 17 (0.27) 0 0 16 (0.07) 3 (0.01) 76 (0.08)
Cardiomegaly 20 (0.36) 26 (0.42) 5 (0.06) 1 (0.68) 97 (0.41) 9 (0.02) 164 (0.17)
Cardiomyopathy 6 (0.11) 27 (0.43) 6 (0.07) 0 32 (0.14) 17 (0.03) 91 (0.09)
Cardiovascular disorder 10 (0.18) 7 (0.11) 8 (0.09) 0 20 (0.08) 23 (0.04) 73 (0.08)
Cellulitis 5 (0.09) 12 (0.19) 11 (0.13) 0 114 (0.48) 924 (1.75) 1082 (1.12)
Cerebral haemorrhage 78 (1.41) 64 (1.03) 16 (0.18) 0 83 (0.35) 17 (0.03) 268 (0.28)
Cerebral infarction 13 (0.24) 57 (0.92) 32 (0.36) 0 126 (0.53) 15 (0.03) 249 (0.26)
Cerebral thrombosis 15 (0.27) 32 (0.51) 10 (0.11) 0 47 (0.20) 4 (0.01) 110 (0.11)
Cerebral venous sinus thrombosis 5 (0.09) 51 (0.82) 6 (0.07) 0 55 (0.23) 7 (0.01) 124 (0.13)
Cerebrovascular accident 144 (2.61) 381 (6.12) 194 (2.21) 0 625 (2.65) 238 (0.45) 1630 (1.68)
Chest X-ray 5 (0.09) 28 (0.45) 14 (0.16) 0 51 (0.22) 0 98 (0.10)
Chest X-ray abnormal 27 (0.49) 15 (0.24) 2 (0.02) 0 201 (0.85) 0 246 (0.25)
Chest X-ray normal 2 (0.04) 6 (0.10) 4 (0.05) 0 62 (0.26) 0 74 (0.08)
Chest discomfort 34 (0.62) 211 (3.39) 117 (1.33) 2 (1.37) 622 (2.63) 514 (0.98) 1525 (1.57)
Chest pain 98 (1.78) 517 (8.30) 354 (4.03) 2 (1.37) 1961 (8.30) 1416 (2.69) 4412 (4.55)
Chills 81 (1.47) 232 (3.73) 1512 (17.20) 6 (4.11) 1124 (4.76) 3550 (6.74) 6564 (6.77)
Choking 4 (0.07) 7 (0.11) 1 (0.01) 0 12 (0.05) 48 (0.09) 73 (0.08)
Cholelithiasis 2 (0.04) 5 (0.08) 3 (0.03) 0 38 (0.16) 0 52 (0.05)
Chromaturia 1 (0.02) 13 (0.21) 8 (0.09) 0 34 (0.14) 19 (0.04) 77 (0.08)
Chronic kidney disease 12 (0.22) 5 (0.08) 3 (0.03) 0 39 (0.17) 11 (0.02) 72 (0.07)
Chronic obstructive pulmonary disease 25 (0.45) 8 (0.13) 2 (0.02) 0 95 (0.40) 7 (0.01) 142 (0.15)
Circulatory collapse 15 (0.27) 12 (0.19) 2 (0.02) 0 21 (0.09) 81 (0.15) 139 (0.14)
Cluster headache 0 1 (0.02) 13 (0.15) 0 5 (0.02) 39 (0.07) 58 (0.06)
Cognitive disorder 10 (0.18) 11 (0.18) 62 (0.71) 0 36 (0.15) 20 (0.04) 142 (0.15)
Cold sweat 12 (0.22) 23 (0.37) 42 (0.48) 0 84 (0.36) 198 (0.38) 369 (0.38)
Colitis 3 (0.05) 10 (0.16) 3 (0.03) 0 49 (0.21) 10 (0.02) 76 (0.08)
Colitis ulcerative 0 1 (0.02) 8 (0.09) 0 20 (0.08) 65 (0.12) 96 (0.10)
Coma 14 (0.25) 19 (0.31) 1 (0.01) 0 17 (0.07) 6 (0.01) 65 (0.07)
Computerised tomogram 5 (0.09) 47 (0.75) 33 (0.38) 1 (0.68) 55 (0.23) 0 141 (0.15)
Computerised tomogram abdomen abnormal 4 (0.07) 10 (0.16) 2 (0.02) 0 35 (0.15) 0 51 (0.05)
Computerised tomogram head normal 2 (0.04) 4 (0.06) 6 (0.07) 0 41 (0.17) 0 53 (0.05)
Computerised tomogram thorax abnormal 4 (0.07) 31 (0.50) 3 (0.03) 0 61 (0.26) 0 99 (0.10)
Condition aggravated 141 (2.56) 183 (2.94) 356 (4.05) 1 (0.68) 693 (2.93) 168 (0.32) 1581 (1.63)
Confusional state 61 (1.11) 98 (1.57) 139 (1.58) 0 446 (1.89) 200 (0.38) 992 (1.02)
Conjunctival haemorrhage 0 2 (0.03) 3 (0.03) 0 3 (0.01) 55 (0.10) 63 (0.06)
Constipation 3 (0.05) 8 (0.13) 25 (0.28) 0 64 (0.27) 44 (0.08) 146 (0.15)
Contusion 3 (0.05) 40 (0.64) 52 (0.59) 0 99 (0.42) 174 (0.33) 377 (0.39)
Coordination abnormal 2 (0.04) 7 (0.11) 20 (0.23) 0 25 (0.11) 11 (0.02) 66 (0.07)
Coronary artery disease 17 (0.31) 17 (0.27) 4 (0.05) 0 41 (0.17) 1 (0.00) 84 (0.09)
Coronary artery occlusion 8 (0.14) 34 (0.55) 1 (0.01) 0 29 (0.12) 3 (0.01) 78 (0.08)
Cough 165 (2.99) 157 (2.52) 150 (1.71) 1 (0.68) 1116 (4.72) 504 (0.96) 2140 (2.21)
Crohn's disease 0 1 (0.02) 3 (0.03) 0 13 (0.06) 39 (0.07) 59 (0.06)
Crying 0 4 (0.06) 19 (0.22) 0 12 (0.05) 18 (0.03) 53 (0.05)
Cyanosis 28 (0.51) 14 (0.22) 13 (0.15) 0 27 (0.11) 17 (0.03) 104 (0.11)
Deafness 1 (0.02) 3 (0.05) 96 (1.09) 0 17 (0.07) 346 (0.66) 468 (0.48)
Deafness neurosensory 0 2 (0.03) 58 (0.66) 0 2 (0.01) 54 (0.10) 118 (0.12)
Deafness unilateral 0 2 (0.03) 148 (1.68) 0 12 (0.05) 218 (0.41) 386 (0.40)
Death 2729 (49.46) 1 (0.02) 0 0 2 (0.01) 2 (0.00) 2734 (2.82)
Decreased appetite 106 (1.92) 71 (1.14) 154 (1.75) 1 (0.68) 415 (1.76) 423 (0.80) 1212 (1.25)
Deep vein thrombosis 24 (0.43) 331 (5.31) 19 (0.22) 2 (1.37) 392 (1.66) 587 (1.11) 1388 (1.43)
Dehydration 22 (0.40) 53 (0.85) 31 (0.35) 0 231 (0.98) 68 (0.13) 419 (0.43)
Delirium 12 (0.22) 20 (0.32) 18 (0.20) 0 39 (0.17) 160 (0.30) 260 (0.27)
Dementia 14 (0.25) 7 (0.11) 9 (0.10) 0 19 (0.08) 34 (0.06) 96 (0.10)
Depressed level of consciousness 18 (0.33) 20 (0.32) 6 (0.07) 0 57 (0.24) 178 (0.34) 295 (0.30)
Depressed mood 1 (0.02) 6 (0.10) 18 (0.20) 2 (1.37) 4 (0.02) 74 (0.14) 106 (0.11)
Depression 3 (0.05) 20 (0.32) 54 (0.61) 1 (0.68) 28 (0.12) 71 (0.13) 182 (0.19)
Dermatitis 0 2 (0.03) 11 (0.13) 0 8 (0.03) 29 (0.06) 51 (0.05)
Dermatitis allergic 0 2 (0.03) 10 (0.11) 0 9 (0.04) 49 (0.09) 71 (0.07)
Dermatitis bullous 0 0 4 (0.05) 0 8 (0.03) 42 (0.08) 54 (0.06)
Diabetes mellitus 13 (0.24) 16 (0.26) 10 (0.11) 0 25 (0.11) 34 (0.06) 101 (0.10)
Diabetic ketoacidosis 5 (0.09) 21 (0.34) 3 (0.03) 0 36 (0.15) 3 (0.01) 70 (0.07)
Diarrhoea 73 (1.32) 135 (2.17) 255 (2.90) 2 (1.37) 748 (3.17) 988 (1.88) 2244 (2.31)
Diarrhoea haemorrhagic 3 (0.05) 6 (0.10) 1 (0.01) 0 12 (0.05) 49 (0.09) 73 (0.08)
Diplegia 0 6 (0.10) 13 (0.15) 0 5 (0.02) 26 (0.05) 51 (0.05)
Diplopia 0 25 (0.40) 66 (0.75) 0 95 (0.40) 42 (0.08) 233 (0.24)
Discomfort 17 (0.31) 21 (0.34) 54 (0.61) 0 78 (0.33) 101 (0.19) 278 (0.29)
Disease recurrence 1 (0.02) 1 (0.02) 9 (0.10) 0 14 (0.06) 30 (0.06) 55 (0.06)
Disorientation 10 (0.18) 35 (0.56) 48 (0.55) 0 93 (0.39) 70 (0.13) 263 (0.27)
Disturbance in attention 1 (0.02) 16 (0.26) 75 (0.85) 0 57 (0.24) 118 (0.22) 270 (0.28)
Diverticulitis 0 2 (0.03) 2 (0.02) 0 45 (0.19) 43 (0.08) 93 (0.10)
Dizziness 64 (1.16) 354 (5.68) 725 (8.25) 4 (2.74) 1370 (5.80) 2380 (4.52) 4973 (5.13)
Dizziness postural 0 2 (0.03) 22 (0.25) 0 23 (0.10) 159 (0.30) 207 (0.21)
Drug ineffective 14 (0.25) 5 (0.08) 2 (0.02) 0 70 (0.30) 49 (0.09) 144 (0.15)
Dry eye 0 1 (0.02) 25 (0.28) 0 7 (0.03) 26 (0.05) 59 (0.06)
Dry mouth 0 10 (0.16) 21 (0.24) 0 32 (0.14) 77 (0.15) 141 (0.15)
Dry skin 1 (0.02) 1 (0.02) 8 (0.09) 0 3 (0.01) 50 (0.09) 63 (0.06)
Dysarthria 11 (0.20) 67 (1.08) 57 (0.65) 0 188 (0.80) 41 (0.08) 377 (0.39)
Dysgeusia 1 (0.02) 13 (0.21) 24 (0.27) 0 19 (0.08) 137 (0.26) 196 (0.20)
Dyskinesia 1 (0.02) 11 (0.18) 22 (0.25) 0 47 (0.20) 21 (0.04) 104 (0.11)
Dysmenorrhoea 0 4 (0.06) 75 (0.85) 0 18 (0.08) 316 (0.60) 415 (0.43)
Dyspepsia 6 (0.11) 16 (0.26) 23 (0.26) 0 38 (0.16) 120 (0.23) 205 (0.21)
Dysphagia 25 (0.45) 84 (1.35) 56 (0.64) 0 140 (0.59) 56 (0.11) 382 (0.39)
Dysphonia 5 (0.09) 24 (0.39) 19 (0.22) 0 50 (0.21) 32 (0.06) 134 (0.14)
Dyspnoea 491 (8.90) 983 (15.78) 545 (6.20) 2 (1.37) 3062 (12.96) 1579 (3.00) 6877 (7.09)
Dyspnoea exertional 14 (0.25) 67 (1.08) 31 (0.35) 0 191 (0.81) 53 (0.10) 371 (0.38)
Dysstasia 8 (0.14) 32 (0.51) 87 (0.99) 0 102 (0.43) 24 (0.05) 261 (0.27)
Dysuria 2 (0.04) 9 (0.14) 9 (0.10) 0 38 (0.16) 20 (0.04) 79 (0.08)
Ear discomfort 0 8 (0.13) 75 (0.85) 0 17 (0.07) 22 (0.04) 123 (0.13)
Ear pain 1 (0.02) 10 (0.16) 91 (1.03) 1 (0.68) 42 (0.18) 217 (0.41) 363 (0.37)
Echocardiogram 2 (0.04) 40 (0.64) 20 (0.23) 3 (2.05) 73 (0.31) 0 138 (0.14)
Echocardiogram abnormal 4 (0.07) 19 (0.31) 7 (0.08) 0 44 (0.19) 0 75 (0.08)
Eczema 0 1 (0.02) 13 (0.15) 0 11 (0.05) 51 (0.10) 76 (0.08)
Ejection fraction decreased 6 (0.11) 19 (0.31) 2 (0.02) 0 37 (0.16) 1 (0.00) 66 (0.07)
Electric shock sensation 0 2 (0.03) 29 (0.33) 0 7 (0.03) 11 (0.02) 51 (0.05)
Electrocardiogram 3 (0.05) 38 (0.61) 21 (0.24) 0 51 (0.22) 1 (0.00) 114 (0.12)
Electrocardiogram abnormal 7 (0.13) 22 (0.35) 8 (0.09) 0 68 (0.29) 1 (0.00) 107 (0.11)
Electrocardiogram normal 3 (0.05) 11 (0.18) 10 (0.11) 0 41 (0.17) 0 65 (0.07)
Encephalitis 3 (0.05) 17 (0.27) 4 (0.05) 0 47 (0.20) 10 (0.02) 85 (0.09)
Encephalopathy 19 (0.34) 21 (0.34) 7 (0.08) 0 89 (0.38) 9 (0.02) 152 (0.16)
Endotracheal intubation 59 (1.07) 27 (0.43) 1 (0.01) 0 39 (0.17) 0 130 (0.13)
Epilepsy 6 (0.11) 25 (0.40) 9 (0.10) 0 93 (0.39) 99 (0.19) 235 (0.24)
Epistaxis 14 (0.25) 36 (0.58) 26 (0.30) 1 (0.68) 62 (0.26) 124 (0.24) 269 (0.28)
Erectile dysfunction 0 0 7 (0.08) 0 1 (0.00) 59 (0.11) 67 (0.07)
Erysipelas 1 (0.02) 2 (0.03) 5 (0.06) 0 14 (0.06) 81 (0.15) 105 (0.11)
Erythema 11 (0.20) 76 (1.22) 106 (1.21) 2 (1.37) 249 (1.05) 522 (0.99) 977 (1.01)
Erythema multiforme 0 1 (0.02) 1 (0.01) 0 17 (0.07) 185 (0.35) 204 (0.21)
Exercise tolerance decreased 0 5 (0.08) 29 (0.33) 0 17 (0.07) 15 (0.03) 71 (0.07)
Exposure during pregnancy 0 10 (0.16) 7 (0.08) 23 (15.75) 79 (0.33) 31 (0.06) 153 (0.16)
Exposure to SARS-CoV-2 13 (0.24) 3 (0.05) 2 (0.02) 0 79 (0.33) 3 (0.01) 103 (0.11)
Extensive swelling of vaccinated limb 1 (0.02) 6 (0.10) 279 (3.17) 0 9 (0.04) 36 (0.07) 331 (0.34)
Extrasystoles 1 (0.02) 19 (0.31) 25 (0.28) 0 22 (0.09) 48 (0.09) 115 (0.12)
Eye haemorrhage 1 (0.02) 3 (0.05) 9 (0.10) 0 7 (0.03) 101 (0.19) 128 (0.13)
Eye irritation 0 2 (0.03) 14 (0.16) 0 13 (0.06) 21 (0.04) 51 (0.05)
Eye movement disorder 3 (0.05) 7 (0.11) 12 (0.14) 0 23 (0.10) 5 (0.01) 52 (0.05)
Eye pain 0 10 (0.16) 110 (1.25) 0 52 (0.22) 248 (0.47) 424 (0.44)
Eye swelling 0 18 (0.29) 26 (0.30) 0 22 (0.09) 87 (0.17) 155 (0.16)
Face oedema 0 6 (0.10) 4 (0.05) 0 20 (0.08) 49 (0.09) 79 (0.08)
Facial pain 0 3 (0.05) 28 (0.32) 0 17 (0.07) 40 (0.08) 89 (0.09)
Facial paralysis 1 (0.02) 44 (0.71) 113 (1.29) 1 (0.68) 259 (1.10) 866 (1.64) 1305 (1.35)
Facial paresis 1 (0.02) 6 (0.10) 27 (0.31) 0 70 (0.30) 54 (0.10) 160 (0.16)
Fall 94 (1.70) 95 (1.53) 111 (1.26) 0 540 (2.29) 88 (0.17) 981 (1.01)
Fatigue 179 (3.24) 440 (7.06) 2359 (26.83) 9 (6.16) 1610 (6.82) 5090 (9.66) 9796 (10.10)
Fear 1 (0.02) 7 (0.11) 20 (0.23) 0 16 (0.07) 7 (0.01) 51 (0.05)
Feeding disorder 8 (0.14) 16 (0.26) 23 (0.26) 0 58 (0.25) 42 (0.08) 154 (0.16)
Feeling abnormal 37 (0.67) 110 (1.77) 250 (2.84) 2 (1.37) 326 (1.38) 330 (0.63) 1085 (1.12)
Feeling cold 6 (0.11) 31 (0.50) 79 (0.90) 0 59 (0.25) 306 (0.58) 484 (0.50)
Feeling hot 8 (0.14) 27 (0.43) 78 (0.89) 0 150 (0.64) 262 (0.50) 529 (0.55)
Feeling of body temperature change 3 (0.05) 4 (0.06) 42 (0.48) 1 (0.68) 25 (0.11) 106 (0.20) 182 (0.19)
Fibrin D dimer 3 (0.05) 17 (0.27) 3 (0.03) 0 43 (0.18) 1 (0.00) 67 (0.07)
Fibrin D dimer increased 10 (0.18) 21 (0.34) 9 (0.10) 0 104 (0.44) 34 (0.06) 182 (0.19)
Fibromyalgia 0 0 26 (0.30) 0 5 (0.02) 22 (0.04) 53 (0.05)
Flank pain 3 (0.05) 21 (0.34) 17 (0.19) 0 44 (0.19) 14 (0.03) 99 (0.10)
Fluid retention 5 (0.09) 7 (0.11) 12 (0.14) 0 24 (0.10) 6 (0.01) 56 (0.06)
Flushing 2 (0.04) 31 (0.50) 17 (0.19) 0 68 (0.29) 62 (0.12) 181 (0.19)
Foetal death 4 (0.07) 3 (0.05) 1 (0.01) 10 (6.85) 18 (0.08) 25 (0.05) 63 (0.06)
Full blood count 7 (0.13) 18 (0.29) 13 (0.15) 1 (0.68) 64 (0.27) 0 104 (0.11)
Gait disturbance 13 (0.24) 80 (1.28) 223 (2.54) 0 333 (1.41) 104 (0.20) 785 (0.81)
Gait inability 17 (0.31) 48 (0.77) 118 (1.34) 1 (0.68) 162 (0.69) 25 (0.05) 382 (0.39)
Gastrointestinal disorder 5 (0.09) 6 (0.10) 10 (0.11) 0 23 (0.10) 15 (0.03) 59 (0.06)
Gastrointestinal haemorrhage 21 (0.38) 21 (0.34) 1 (0.01) 0 48 (0.20) 19 (0.04) 115 (0.12)
Gastrointestinal pain 0 1 (0.02) 12 (0.14) 0 14 (0.06) 31 (0.06) 59 (0.06)
Gastrooesophageal reflux disease 2 (0.04) 12 (0.19) 9 (0.10) 0 31 (0.13) 27 (0.05) 81 (0.08)
Gaze palsy 2 (0.04) 7 (0.11) 4 (0.05) 0 13 (0.06) 67 (0.13) 96 (0.10)
General physical health deterioration 125 (2.27) 22 (0.35) 26 (0.30) 0 74 (0.31) 18 (0.03) 292 (0.30)
Generalised tonic-clonic seizure 4 (0.07) 18 (0.29) 7 (0.08) 0 54 (0.23) 110 (0.21) 196 (0.20)
Gout 0 1 (0.02) 15 (0.17) 0 20 (0.08) 16 (0.03) 54 (0.06)
Grip strength decreased 2 (0.04) 4 (0.06) 27 (0.31) 0 13 (0.06) 9 (0.02) 55 (0.06)
Groin pain 1 (0.02) 7 (0.11) 18 (0.20) 0 14 (0.06) 21 (0.04) 65 (0.07)
Guillain-Barre syndrome 5 (0.09) 67 (1.08) 77 (0.88) 0 184 (0.78) 78 (0.15) 417 (0.43)
Haematemesis 14 (0.25) 8 (0.13) 1 (0.01) 0 18 (0.08) 54 (0.10) 98 (0.10)
Haematochezia 4 (0.07) 5 (0.08) 8 (0.09) 0 38 (0.16) 154 (0.29) 218 (0.22)
Haematoma 6 (0.11) 15 (0.24) 14 (0.16) 0 34 (0.14) 40 (0.08) 112 (0.12)
Haematuria 5 (0.09) 9 (0.14) 6 (0.07) 0 38 (0.16) 30 (0.06) 95 (0.10)
Haemoglobin decreased 17 (0.31) 16 (0.26) 1 (0.01) 0 70 (0.30) 5 (0.01) 111 (0.11)
Haemoptysis 14 (0.25) 28 (0.45) 3 (0.03) 0 39 (0.17) 9 (0.02) 99 (0.10)
Haemorrhage 23 (0.42) 26 (0.42) 18 (0.20) 1 (0.68) 51 (0.22) 332 (0.63) 467 (0.48)
Haemorrhagic stroke 26 (0.47) 13 (0.21) 3 (0.03) 0 20 (0.08) 6 (0.01) 71 (0.07)
Hallucination 5 (0.09) 7 (0.11) 25 (0.28) 0 56 (0.24) 386 (0.73) 491 (0.51)
Hallucination, auditory 0 2 (0.03) 2 (0.02) 0 10 (0.04) 38 (0.07) 53 (0.05)
Hallucination, visual 0 0 5 (0.06) 0 7 (0.03) 46 (0.09) 60 (0.06)
Head discomfort 1 (0.02) 8 (0.13) 51 (0.58) 0 36 (0.15) 56 (0.11) 155 (0.16)
Head injury 14 (0.25) 20 (0.32) 11 (0.13) 0 84 (0.36) 26 (0.05) 161 (0.17)
Headache 93 (1.69) 458 (7.35) 2337 (26.58) 10 (6.85) 1798 (7.61) 6845 (12.99) 11642 (12.00)
Heart rate 0 3 (0.05) 13 (0.15) 0 17 (0.07) 118 (0.22) 151 (0.16)
Heart rate decreased 5 (0.09) 10 (0.16) 3 (0.03) 0 28 (0.12) 16 (0.03) 63 (0.06)
Heart rate increased 10 (0.18) 83 (1.33) 118 (1.34) 2 (1.37) 223 (0.94) 297 (0.56) 749 (0.77)
Heart rate irregular 4 (0.07) 14 (0.22) 31 (0.35) 0 48 (0.20) 65 (0.12) 165 (0.17)
Heavy menstrual bleeding 0 17 (0.27) 118 (1.34) 2 (1.37) 47 (0.20) 571 (1.08) 756 (0.78)
Hemiparesis 9 (0.16) 53 (0.85) 74 (0.84) 0 160 (0.68) 106 (0.20) 421 (0.43)
Hemiplegia 6 (0.11) 31 (0.50) 39 (0.44) 0 43 (0.18) 45 (0.09) 176 (0.18)
Herpes zoster 6 (0.11) 17 (0.27) 80 (0.91) 0 132 (0.56) 371 (0.70) 612 (0.63)
Hospitalisation 10 (0.18) 2 (0.03) 0 0 222 (0.94) 0 250 (0.26)
Hot flush 0 17 (0.27) 47 (0.53) 1 (0.68) 35 (0.15) 205 (0.39) 307 (0.32)
Hyperaesthesia 1 (0.02) 1 (0.02) 24 (0.27) 1 (0.68) 5 (0.02) 38 (0.07) 71 (0.07)
Hyperglycaemia 5 (0.09) 12 (0.19) 1 (0.01) 0 48 (0.20) 12 (0.02) 83 (0.09)
Hyperhidrosis 23 (0.42) 113 (1.81) 207 (2.35) 0 301 (1.27) 774 (1.47) 1434 (1.48)
Hyperkalaemia 12 (0.22) 3 (0.05) 0 0 30 (0.13) 6 (0.01) 61 (0.06)
Hyperpyrexia 9 (0.16) 11 (0.18) 6 (0.07) 0 30 (0.13) 227 (0.43) 285 (0.29)
Hypersensitivity 5 (0.09) 78 (1.25) 49 (0.56) 1 (0.68) 179 (0.76) 390 (0.74) 708 (0.73)
Hypersomnia 5 (0.09) 20 (0.32) 27 (0.31) 1 (0.68) 29 (0.12) 36 (0.07) 123 (0.13)
Hypertension 38 (0.69) 132 (2.12) 82 (0.93) 1 (0.68) 446 (1.89) 277 (0.53) 1004 (1.04)
Hypertensive crisis 3 (0.05) 20 (0.32) 0 0 44 (0.19) 71 (0.13) 140 (0.14)
Hyperthyroidism 1 (0.02) 5 (0.08) 12 (0.14) 0 6 (0.03) 56 (0.11) 80 (0.08)
Hyperventilation 4 (0.07) 8 (0.13) 2 (0.02) 0 45 (0.19) 16 (0.03) 77 (0.08)
Hypervolaemia 6 (0.11) 3 (0.05) 0 0 39 (0.17) 0 53 (0.05)
Hypoacusis 2 (0.04) 5 (0.08) 90 (1.02) 0 32 (0.14) 54 (0.10) 185 (0.19)
Hypoaesthesia 5 (0.09) 144 (2.31) 465 (5.29) 0 611 (2.59) 542 (1.03) 1797 (1.85)
Hypoaesthesia oral 1 (0.02) 15 (0.24) 39 (0.44) 0 65 (0.28) 61 (0.12) 185 (0.19)
Hypoglycaemia 6 (0.11) 10 (0.16) 4 (0.05) 0 22 (0.09) 14 (0.03) 58 (0.06)
Hypokalaemia 9 (0.16) 7 (0.11) 2 (0.02) 0 56 (0.24) 24 (0.05) 105 (0.11)
Hypokinesia 3 (0.05) 3 (0.05) 18 (0.20) 0 30 (0.13) 23 (0.04) 81 (0.08)
Hyponatraemia 12 (0.22) 14 (0.22) 3 (0.03) 0 82 (0.35) 3 (0.01) 125 (0.13)
Hypophagia 20 (0.36) 14 (0.22) 5 (0.06) 0 94 (0.40) 2 (0.00) 142 (0.15)
Hypopnoea 8 (0.14) 11 (0.18) 5 (0.06) 0 14 (0.06) 19 (0.04) 61 (0.06)
Hypotension 90 (1.63) 88 (1.41) 40 (0.45) 0 297 (1.26) 156 (0.30) 702 (0.72)
Hypothermia 2 (0.04) 4 (0.06) 2 (0.02) 0 10 (0.04) 37 (0.07) 57 (0.06)
Hypothyroidism 2 (0.04) 3 (0.05) 9 (0.10) 0 16 (0.07) 30 (0.06) 64 (0.07)
Hypotonia 4 (0.07) 5 (0.08) 10 (0.11) 0 24 (0.10) 14 (0.03) 57 (0.06)
Hypoxia 129 (2.34) 71 (1.14) 4 (0.05) 0 491 (2.08) 57 (0.11) 792 (0.82)
Illness 30 (0.54) 23 (0.37) 72 (0.82) 2 (1.37) 85 (0.36) 471 (0.89) 696 (0.72)
Immediate post-injection reaction 7 (0.13) 30 (0.48) 60 (0.68) 1 (0.68) 42 (0.18) 3 (0.01) 143 (0.15)
Immune thrombocytopenia 4 (0.07) 68 (1.09) 4 (0.05) 0 118 (0.50) 47 (0.09) 243 (0.25)
Immunisation reaction 0 0 0 0 3 (0.01) 72 (0.14) 75 (0.08)
Impaired driving ability 3 (0.05) 20 (0.32) 49 (0.56) 0 31 (0.13) 12 (0.02) 119 (0.12)
Impaired work ability 5 (0.09) 56 (0.90) 211 (2.40) 2 (1.37) 90 (0.38) 66 (0.13) 445 (0.46)
Inappropriate schedule of product administration 8 (0.14) 5 (0.08) 14 (0.16) 2 (1.37) 53 (0.22) 10 (0.02) 93 (0.10)
Infection 8 (0.14) 14 (0.22) 21 (0.24) 0 98 (0.41) 52 (0.10) 196 (0.20)
Inflammation 7 (0.13) 34 (0.55) 94 (1.07) 0 119 (0.50) 96 (0.18) 356 (0.37)
Influenza 2 (0.04) 13 (0.21) 54 (0.61) 0 96 (0.41) 444 (0.84) 611 (0.63)
Influenza like illness 15 (0.27) 37 (0.59) 254 (2.89) 0 223 (0.94) 840 (1.59) 1379 (1.42)
Injected limb mobility decreased 2 (0.04) 6 (0.10) 107 (1.22) 0 8 (0.03) 32 (0.06) 156 (0.16)
Injection site erythema 3 (0.05) 13 (0.21) 88 (1.00) 1 (0.68) 77 (0.33) 184 (0.35) 366 (0.38)
Injection site mass 1 (0.02) 1 (0.02) 12 (0.14) 0 4 (0.02) 86 (0.16) 104 (0.11)
Injection site pain 15 (0.27) 35 (0.56) 266 (3.03) 1 (0.68) 187 (0.79) 734 (1.39) 1245 (1.28)
Injection site pruritus 3 (0.05) 7 (0.11) 33 (0.38) 1 (0.68) 19 (0.08) 62 (0.12) 125 (0.13)
Injection site rash 0 8 (0.13) 20 (0.23) 0 17 (0.07) 92 (0.17) 137 (0.14)
Injection site reaction 2 (0.04) 6 (0.10) 839 (9.54) 1 (0.68) 36 (0.15) 145 (0.28) 1030 (1.06)
Injection site swelling 3 (0.05) 17 (0.27) 75 (0.85) 0 78 (0.33) 117 (0.22) 293 (0.30)
Injection site warmth 1 (0.02) 8 (0.13) 33 (0.38) 0 11 (0.05) 59 (0.11) 112 (0.12)
Insomnia 12 (0.22) 26 (0.42) 169 (1.92) 2 (1.37) 79 (0.33) 426 (0.81) 724 (0.75)
Intensive care 44 (0.80) 57 (0.92) 3 (0.03) 0 74 (0.31) 0 178 (0.18)
Interchange of vaccine products 1 (0.02) 8 (0.13) 9 (0.10) 0 23 (0.10) 53 (0.10) 97 (0.10)
Intermenstrual bleeding 0 3 (0.05) 26 (0.30) 2 (1.37) 13 (0.06) 167 (0.32) 211 (0.22)
Interstitial lung disease 11 (0.20) 11 (0.18) 3 (0.03) 0 41 (0.17) 8 (0.02) 80 (0.08)
Intracardiac thrombus 8 (0.14) 21 (0.34) 5 (0.06) 0 14 (0.06) 1 (0.00) 52 (0.05)
Irritability 2 (0.04) 5 (0.08) 11 (0.13) 0 11 (0.05) 35 (0.07) 64 (0.07)
Ischaemic stroke 25 (0.45) 69 (1.11) 37 (0.42) 0 196 (0.83) 22 (0.04) 353 (0.36)
Jaundice 3 (0.05) 5 (0.08) 2 (0.02) 0 32 (0.14) 8 (0.02) 55 (0.06)
Joint range of motion decreased 1 (0.02) 7 (0.11) 60 (0.68) 0 14 (0.06) 3 (0.01) 86 (0.09)
Joint stiffness 1 (0.02) 4 (0.06) 41 (0.47) 0 13 (0.06) 56 (0.11) 117 (0.12)
Joint swelling 2 (0.04) 21 (0.34) 89 (1.01) 0 52 (0.22) 69 (0.13) 238 (0.25)
Kidney infection 1 (0.02) 4 (0.06) 5 (0.06) 0 19 (0.08) 24 (0.05) 53 (0.05)
Laboratory test 13 (0.24) 47 (0.75) 38 (0.43) 1 (0.68) 67 (0.28) 0 166 (0.17)
Lacrimation increased 1 (0.02) 5 (0.08) 16 (0.18) 0 10 (0.04) 24 (0.05) 56 (0.06)
Lactic acidosis 15 (0.27) 8 (0.13) 1 (0.01) 0 35 (0.15) 2 (0.00) 64 (0.07)
Lethargy 46 (0.83) 49 (0.79) 60 (0.68) 1 (0.68) 166 (0.70) 341 (0.65) 677 (0.70)
Leukocytosis 10 (0.18) 9 (0.14) 3 (0.03) 0 85 (0.36) 3 (0.01) 118 (0.12)
Leukopenia 5 (0.09) 6 (0.10) 1 (0.01) 0 26 (0.11) 16 (0.03) 57 (0.06)
Limb discomfort 3 (0.05) 27 (0.43) 84 (0.96) 0 142 (0.60) 239 (0.45) 503 (0.52)
Limb injury 1 (0.02) 3 (0.05) 19 (0.22) 0 17 (0.07) 34 (0.06) 75 (0.08)
Lip swelling 1 (0.02) 42 (0.67) 20 (0.23) 2 (1.37) 83 (0.35) 133 (0.25) 288 (0.30)
Loss of consciousness 93 (1.69) 199 (3.20) 73 (0.83) 1 (0.68) 480 (2.03) 2953 (5.60) 3910 (4.03)
Loss of personal independence in daily activities 4 (0.07) 47 (0.75) 181 (2.06) 0 84 (0.36) 29 (0.06) 363 (0.37)
Lower respiratory tract infection 1 (0.02) 5 (0.08) 10 (0.11) 0 12 (0.05) 67 (0.13) 96 (0.10)
Lung consolidation 7 (0.13) 3 (0.05) 1 (0.01) 0 40 (0.17) 0 54 (0.06)
Lung disorder 13 (0.24) 7 (0.11) 7 (0.08) 0 70 (0.30) 9 (0.02) 110 (0.11)
Lung infiltration 30 (0.54) 21 (0.34) 0 0 151 (0.64) 0 215 (0.22)
Lung opacity 37 (0.67) 43 (0.69) 4 (0.05) 0 219 (0.93) 1 (0.00) 310 (0.32)
Lymph node pain 1 (0.02) 3 (0.05) 35 (0.40) 0 15 (0.06) 182 (0.35) 237 (0.24)
Lymphadenitis 0 2 (0.03) 12 (0.14) 0 17 (0.07) 37 (0.07) 68 (0.07)
Lymphadenopathy 10 (0.18) 55 (0.88) 284 (3.23) 1 (0.68) 229 (0.97) 1328 (2.52) 1921 (1.98)
Magnetic resonance imaging 3 (0.05) 25 (0.40) 44 (0.50) 1 (0.68) 38 (0.16) 0 111 (0.11)
Magnetic resonance imaging head abnormal 3 (0.05) 14 (0.22) 17 (0.19) 0 19 (0.08) 0 53 (0.05)
Malaise 181 (3.28) 196 (3.15) 1116 (12.69) 8 (5.48) 836 (3.54) 1036 (1.97) 3437 (3.54)
Maternal exposure during breast feeding 0 2 (0.03) 11 (0.13) 0 5 (0.02) 223 (0.42) 241 (0.25)
Maternal exposure during pregnancy 1 (0.02) 16 (0.26) 13 (0.15) 23 (15.75) 68 (0.29) 196 (0.37) 319 (0.33)
Mechanical ventilation 30 (0.54) 11 (0.18) 2 (0.02) 0 13 (0.06) 0 58 (0.06)
Memory impairment 6 (0.11) 23 (0.37) 70 (0.80) 0 109 (0.46) 44 (0.08) 260 (0.27)
Menstrual disorder 0 3 (0.05) 67 (0.76) 1 (0.68) 27 (0.11) 212 (0.40) 313 (0.32)
Menstruation delayed 0 1 (0.02) 38 (0.43) 0 4 (0.02) 239 (0.45) 282 (0.29)
Menstruation irregular 0 1 (0.02) 64 (0.73) 2 (1.37) 18 (0.08) 236 (0.45) 323 (0.33)
Mental fatigue 0 1 (0.02) 18 (0.20) 0 2 (0.01) 31 (0.06) 52 (0.05)
Mental impairment 3 (0.05) 3 (0.05) 29 (0.33) 0 18 (0.08) 171 (0.32) 233 (0.24)
Mental status changes 44 (0.80) 44 (0.71) 9 (0.10) 0 206 (0.87) 2 (0.00) 318 (0.33)
Metabolic function test 5 (0.09) 16 (0.26) 10 (0.11) 0 45 (0.19) 0 76 (0.08)
Migraine 3 (0.05) 35 (0.56) 233 (2.65) 0 134 (0.57) 640 (1.21) 1051 (1.08)
Migraine with aura 0 0 11 (0.13) 2 (1.37) 10 (0.04) 35 (0.07) 58 (0.06)
Mitral valve incompetence 3 (0.05) 9 (0.14) 2 (0.02) 0 32 (0.14) 6 (0.01) 54 (0.06)
Mobility decreased 19 (0.34) 73 (1.17) 212 (2.41) 2 (1.37) 207 (0.88) 43 (0.08) 572 (0.59)
Monoplegia 0 6 (0.10) 24 (0.27) 0 24 (0.10) 115 (0.22) 173 (0.18)
Motor dysfunction 3 (0.05) 5 (0.08) 16 (0.18) 0 31 (0.13) 8 (0.02) 64 (0.07)
Mouth swelling 0 13 (0.21) 5 (0.06) 0 21 (0.09) 16 (0.03) 57 (0.06)
Mouth ulceration 0 4 (0.06) 6 (0.07) 0 12 (0.05) 37 (0.07) 59 (0.06)
Movement disorder 6 (0.11) 11 (0.18) 50 (0.57) 0 47 (0.20) 25 (0.05) 145 (0.15)
Multiple organ dysfunction syndrome 51 (0.92) 8 (0.13) 0 0 6 (0.03) 1 (0.00) 78 (0.08)
Multiple sclerosis 0 4 (0.06) 28 (0.32) 0 22 (0.09) 65 (0.12) 120 (0.12)
Multiple sclerosis relapse 0 1 (0.02) 9 (0.10) 0 24 (0.10) 39 (0.07) 73 (0.08)
Muscle fatigue 0 2 (0.03) 18 (0.20) 0 6 (0.03) 68 (0.13) 95 (0.10)
Muscle rigidity 3 (0.05) 9 (0.14) 10 (0.11) 0 15 (0.06) 14 (0.03) 51 (0.05)
Muscle spasms 7 (0.13) 49 (0.79) 141 (1.60) 3 (2.05) 147 (0.62) 343 (0.65) 700 (0.72)
Muscle tightness 1 (0.02) 13 (0.21) 18 (0.20) 1 (0.68) 23 (0.10) 22 (0.04) 81 (0.08)
Muscle twitching 2 (0.04) 8 (0.13) 53 (0.60) 1 (0.68) 32 (0.14) 55 (0.10) 153 (0.16)
Muscular weakness 20 (0.36) 80 (1.28) 293 (3.33) 1 (0.68) 439 (1.86) 246 (0.47) 1107 (1.14)
Musculoskeletal chest pain 1 (0.02) 15 (0.24) 23 (0.26) 0 42 (0.18) 56 (0.11) 141 (0.15)
Musculoskeletal discomfort 2 (0.04) 6 (0.10) 17 (0.19) 0 18 (0.08) 21 (0.04) 66 (0.07)
Musculoskeletal pain 2 (0.04) 2 (0.03) 22 (0.25) 1 (0.68) 35 (0.15) 120 (0.23) 183 (0.19)
Musculoskeletal stiffness 5 (0.09) 19 (0.31) 187 (2.13) 0 92 (0.39) 316 (0.60) 624 (0.64)
Myalgia 35 (0.63) 160 (2.57) 1722 (19.58) 3 (2.05) 723 (3.06) 2947 (5.59) 5630 (5.80)
Myasthenia gravis 1 (0.02) 9 (0.14) 19 (0.22) 0 21 (0.09) 31 (0.06) 83 (0.09)
Myelitis transverse 0 3 (0.05) 37 (0.42) 0 32 (0.14) 17 (0.03) 94 (0.10)
Myocardial infarction 189 (3.43) 235 (3.77) 6 (0.07) 0 247 (1.05) 97 (0.18) 801 (0.83)
Myocarditis 35 (0.63) 291 (4.67) 69 (0.78) 2 (1.37) 1852 (7.84) 590 (1.12) 2877 (2.97)
Nasal congestion 3 (0.05) 6 (0.10) 22 (0.25) 0 53 (0.22) 58 (0.11) 144 (0.15)
Nasopharyngitis 7 (0.13) 10 (0.16) 37 (0.42) 0 61 (0.26) 194 (0.37) 311 (0.32)
Nausea 99 (1.79) 301 (4.83) 1371 (15.59) 5 (3.42) 1364 (5.77) 3799 (7.21) 7014 (7.23)
Neck pain 10 (0.18) 44 (0.71) 184 (2.09) 2 (1.37) 158 (0.67) 361 (0.69) 768 (0.79)
Nephrolithiasis 1 (0.02) 5 (0.08) 5 (0.06) 0 32 (0.14) 56 (0.11) 100 (0.10)
Nerve injury 0 2 (0.03) 35 (0.40) 0 10 (0.04) 16 (0.03) 64 (0.07)
Nervous system disorder 5 (0.09) 3 (0.05) 25 (0.28) 0 26 (0.11) 21 (0.04) 84 (0.09)
Nervousness 2 (0.04) 1 (0.02) 15 (0.17) 0 13 (0.06) 32 (0.06) 67 (0.07)
Neuralgia 1 (0.02) 11 (0.18) 104 (1.18) 1 (0.68) 53 (0.22) 142 (0.27) 315 (0.32)
Neuralgic amyotrophy 1 (0.02) 1 (0.02) 29 (0.33) 0 17 (0.07) 19 (0.04) 70 (0.07)
Neurological symptom 6 (0.11) 28 (0.45) 41 (0.47) 0 80 (0.34) 10 (0.02) 170 (0.18)
Neuropathy peripheral 1 (0.02) 5 (0.08) 68 (0.77) 0 37 (0.16) 343 (0.65) 467 (0.48)
Night sweats 2 (0.04) 16 (0.26) 42 (0.48) 0 46 (0.19) 220 (0.42) 330 (0.34)
Nightmare 1 (0.02) 3 (0.05) 7 (0.08) 1 (0.68) 5 (0.02) 36 (0.07) 54 (0.06)
Ocular discomfort 0 1 (0.02) 13 (0.15) 0 17 (0.07) 20 (0.04) 53 (0.05)
Ocular hyperaemia 1 (0.02) 8 (0.13) 11 (0.13) 1 (0.68) 20 (0.08) 33 (0.06) 75 (0.08)
Oedema 11 (0.20) 12 (0.19) 17 (0.19) 0 59 (0.25) 37 (0.07) 143 (0.15)
Oedema peripheral 11 (0.20) 27 (0.43) 39 (0.44) 0 111 (0.47) 86 (0.16) 281 (0.29)
Off label use 0 2 (0.03) 4 (0.05) 0 9 (0.04) 51 (0.10) 68 (0.07)
Ophthalmic herpes zoster 0 1 (0.02) 6 (0.07) 1 (0.68) 9 (0.04) 72 (0.14) 89 (0.09)
Optic neuritis 0 2 (0.03) 22 (0.25) 0 30 (0.13) 39 (0.07) 94 (0.10)
Oral herpes 1 (0.02) 4 (0.06) 16 (0.18) 0 13 (0.06) 67 (0.13) 101 (0.10)
Oropharyngeal discomfort 0 10 (0.16) 3 (0.03) 0 24 (0.10) 18 (0.03) 58 (0.06)
Oropharyngeal pain 17 (0.31) 38 (0.61) 96 (1.09) 0 171 (0.72) 418 (0.79) 746 (0.77)
Oxygen saturation decreased 38 (0.69) 36 (0.58) 11 (0.13) 0 120 (0.51) 23 (0.04) 247 (0.25)
Pain 77 (1.40) 259 (4.16) 826 (9.39) 6 (4.11) 875 (3.70) 1892 (3.59) 3989 (4.11)
Pain in extremity 49 (0.89) 291 (4.67) 925 (10.52) 6 (4.11) 655 (2.77) 2774 (5.26) 4742 (4.89)
Pain in jaw 2 (0.04) 13 (0.21) 31 (0.35) 0 42 (0.18) 64 (0.12) 156 (0.16)
Pain of skin 0 6 (0.10) 35 (0.40) 0 8 (0.03) 108 (0.20) 159 (0.16)
Painful respiration 3 (0.05) 20 (0.32) 6 (0.07) 0 56 (0.24) 7 (0.01) 95 (0.10)
Pallor 15 (0.27) 17 (0.27) 12 (0.14) 1 (0.68) 54 (0.23) 55 (0.10) 161 (0.17)
Palpitations 11 (0.20) 181 (2.91) 330 (3.75) 1 (0.68) 589 (2.49) 1222 (2.32) 2357 (2.43)
Pancreatitis 4 (0.07) 13 (0.21) 4 (0.05) 0 56 (0.24) 33 (0.06) 111 (0.11)
Pancreatitis acute 0 12 (0.19) 0 0 65 (0.28) 10 (0.02) 90 (0.09)
Pancytopenia 1 (0.02) 10 (0.16) 1 (0.01) 0 29 (0.12) 6 (0.01) 53 (0.05)
Panic attack 1 (0.02) 6 (0.10) 30 (0.34) 0 16 (0.07) 40 (0.08) 96 (0.10)
Paraesthesia 2 (0.04) 122 (1.96) 393 (4.47) 0 523 (2.21) 861 (1.63) 1921 (1.98)
Paraesthesia oral 0 30 (0.48) 22 (0.25) 0 59 (0.25) 97 (0.18) 210 (0.22)
Paralysis 8 (0.14) 29 (0.47) 65 (0.74) 1 (0.68) 61 (0.26) 163 (0.31) 342 (0.35)
Parosmia 1 (0.02) 5 (0.08) 33 (0.38) 0 13 (0.06) 25 (0.05) 77 (0.08)
Pelvic pain 0 3 (0.05) 17 (0.19) 1 (0.68) 10 (0.04) 21 (0.04) 52 (0.05)
Pemphigoid 2 (0.04) 1 (0.02) 6 (0.07) 0 13 (0.06) 30 (0.06) 52 (0.05)
Periarthritis 0 0 40 (0.45) 0 4 (0.02) 48 (0.09) 92 (0.09)
Pericardial effusion 6 (0.11) 59 (0.95) 8 (0.09) 0 140 (0.59) 78 (0.15) 305 (0.31)
Pericarditis 8 (0.14) 128 (2.06) 36 (0.41) 0 633 (2.68) 649 (1.23) 1468 (1.51)
Peripheral coldness 12 (0.22) 20 (0.32) 26 (0.30) 0 31 (0.13) 91 (0.17) 183 (0.19)
Peripheral swelling 24 (0.43) 158 (2.54) 265 (3.01) 1 (0.68) 290 (1.23) 1085 (2.06) 1855 (1.91)
Petechiae 3 (0.05) 34 (0.55) 10 (0.11) 0 85 (0.36) 29 (0.06) 166 (0.17)
Pharyngeal swelling 0 89 (1.43) 20 (0.23) 0 60 (0.25) 83 (0.16) 258 (0.27)
Photophobia 1 (0.02) 9 (0.14) 58 (0.66) 0 39 (0.17) 130 (0.25) 240 (0.25)
Platelet count decreased 9 (0.16) 38 (0.61) 3 (0.03) 1 (0.68) 52 (0.22) 11 (0.02) 120 (0.12)
Pleural effusion 29 (0.53) 44 (0.71) 12 (0.14) 0 162 (0.69) 8 (0.02) 274 (0.28)
Pleuritic pain 0 16 (0.26) 1 (0.01) 0 55 (0.23) 2 (0.00) 79 (0.08)
Pneumonia 166 (3.01) 117 (1.88) 19 (0.22) 0 611 (2.59) 252 (0.48) 1235 (1.27)
Pneumonia aspiration 20 (0.36) 11 (0.18) 1 (0.01) 0 22 (0.09) 2 (0.00) 60 (0.06)
Pneumonia bacterial 14 (0.25) 1 (0.02) 1 (0.01) 0 35 (0.15) 8 (0.02) 60 (0.06)
Pneumonitis 5 (0.09) 13 (0.21) 1 (0.01) 0 40 (0.17) 9 (0.02) 70 (0.07)
Pneumothorax 9 (0.16) 6 (0.10) 1 (0.01) 0 29 (0.12) 10 (0.02) 59 (0.06)
Pollakiuria 4 (0.07) 5 (0.08) 20 (0.23) 0 26 (0.11) 35 (0.07) 91 (0.09)
Polymenorrhoea 0 0 37 (0.42) 2 (1.37) 9 (0.04) 94 (0.18) 142 (0.15)
Polymyalgia rheumatica 0 1 (0.02) 20 (0.23) 0 11 (0.05) 112 (0.21) 144 (0.15)
Polyneuropathy 0 3 (0.05) 11 (0.13) 0 22 (0.09) 19 (0.04) 57 (0.06)
Poor quality sleep 3 (0.05) 0 21 (0.24) 0 6 (0.03) 69 (0.13) 100 (0.10)
Portal vein thrombosis 4 (0.07) 10 (0.16) 0 0 36 (0.15) 3 (0.01) 53 (0.05)
Positive airway pressure therapy 27 (0.49) 3 (0.05) 1 (0.01) 0 30 (0.13) 0 61 (0.06)
Postmenopausal haemorrhage 0 0 5 (0.06) 0 3 (0.01) 225 (0.43) 233 (0.24)
Presyncope 1 (0.02) 26 (0.42) 49 (0.56) 2 (1.37) 178 (0.75) 223 (0.42) 489 (0.50)
Productive cough 22 (0.40) 11 (0.18) 17 (0.19) 0 119 (0.50) 22 (0.04) 197 (0.20)
Pruritus 7 (0.13) 112 (1.80) 153 (1.74) 3 (2.05) 238 (1.01) 974 (1.85) 1497 (1.54)
Psoriasis 1 (0.02) 2 (0.03) 10 (0.11) 0 7 (0.03) 31 (0.06) 51 (0.05)
Pulmonary congestion 4 (0.07) 9 (0.14) 3 (0.03) 0 36 (0.15) 96 (0.18) 155 (0.16)
Pulmonary embolism 122 (2.21) 773 (12.41) 26 (0.30) 0 961 (4.07) 271 (0.51) 2176 (2.24)
Pulmonary fibrosis 5 (0.09) 2 (0.03) 4 (0.05) 0 28 (0.12) 10 (0.02) 53 (0.05)
Pulmonary hypertension 4 (0.07) 12 (0.19) 1 (0.01) 0 23 (0.10) 12 (0.02) 56 (0.06)
Pulmonary infarction 3 (0.05) 31 (0.50) 1 (0.01) 0 28 (0.12) 9 (0.02) 74 (0.08)
Pulmonary mass 9 (0.16) 11 (0.18) 8 (0.09) 0 43 (0.18) 4 (0.01) 79 (0.08)
Pulmonary oedema 38 (0.69) 41 (0.66) 5 (0.06) 1 (0.68) 99 (0.42) 20 (0.04) 226 (0.23)
Pulmonary pain 0 14 (0.22) 16 (0.18) 0 17 (0.07) 26 (0.05) 73 (0.08)
Pulmonary thrombosis 15 (0.27) 109 (1.75) 11 (0.13) 0 97 (0.41) 20 (0.04) 257 (0.26)
Pulseless electrical activity 33 (0.60) 11 (0.18) 0 0 4 (0.02) 0 54 (0.06)
Purpura 0 7 (0.11) 5 (0.06) 0 25 (0.11) 18 (0.03) 55 (0.06)
Pyrexia 282 (5.11) 527 (8.46) 2111 (24.01) 17 (11.64) 2906 (12.30) 6366 (12.08) 12371 (12.75)
Rash 12 (0.22) 129 (2.07) 228 (2.59) 1 (0.68) 445 (1.88) 1213 (2.30) 2045 (2.11)
Rash erythematous 2 (0.04) 21 (0.34) 34 (0.39) 0 60 (0.25) 337 (0.64) 459 (0.47)
Rash macular 2 (0.04) 8 (0.13) 32 (0.36) 0 22 (0.09) 81 (0.15) 146 (0.15)
Rash papular 0 5 (0.08) 5 (0.06) 0 11 (0.05) 80 (0.15) 102 (0.11)
Rash pruritic 1 (0.02) 12 (0.19) 34 (0.39) 0 51 (0.22) 213 (0.40) 311 (0.32)
Rectal haemorrhage 3 (0.05) 3 (0.05) 3 (0.03) 0 38 (0.16) 65 (0.12) 117 (0.12)
Renal failure 61 (1.11) 36 (0.58) 6 (0.07) 0 59 (0.25) 18 (0.03) 201 (0.21)
Renal impairment 17 (0.31) 9 (0.14) 6 (0.07) 0 36 (0.15) 42 (0.08) 119 (0.12)
Renal pain 2 (0.04) 1 (0.02) 30 (0.34) 0 18 (0.08) 91 (0.17) 142 (0.15)
Respiration abnormal 8 (0.14) 7 (0.11) 6 (0.07) 0 26 (0.11) 15 (0.03) 66 (0.07)
Respiratory arrest 81 (1.47) 25 (0.40) 1 (0.01) 0 16 (0.07) 18 (0.03) 155 (0.16)
Respiratory disorder 14 (0.25) 10 (0.16) 13 (0.15) 0 24 (0.10) 8 (0.02) 72 (0.07)
Respiratory distress 39 (0.71) 32 (0.51) 6 (0.07) 0 75 (0.32) 59 (0.11) 226 (0.23)
Respiratory failure 126 (2.28) 50 (0.80) 7 (0.08) 0 116 (0.49) 6 (0.01) 317 (0.33)
Respiratory tract congestion 16 (0.29) 4 (0.06) 11 (0.13) 0 110 (0.47) 2 (0.00) 149 (0.15)
Restlessness 6 (0.11) 7 (0.11) 10 (0.11) 0 19 (0.08) 61 (0.12) 104 (0.11)
Resuscitation 45 (0.82) 11 (0.18) 0 0 11 (0.05) 0 69 (0.07)
Retching 1 (0.02) 14 (0.22) 17 (0.19) 0 39 (0.17) 32 (0.06) 104 (0.11)
Retinal detachment 0 0 11 (0.13) 0 18 (0.08) 23 (0.04) 53 (0.05)
Retinal vein occlusion 0 2 (0.03) 28 (0.32) 0 5 (0.02) 36 (0.07) 71 (0.07)
Rhabdomyolysis 5 (0.09) 22 (0.35) 6 (0.07) 0 62 (0.26) 24 (0.05) 124 (0.13)
Rheumatoid arthritis 5 (0.09) 2 (0.03) 43 (0.49) 0 19 (0.08) 214 (0.41) 286 (0.29)
Rhinorrhoea 13 (0.24) 4 (0.06) 27 (0.31) 0 80 (0.34) 125 (0.24) 252 (0.26)
SARS-CoV-2 test negative 8 (0.14) 11 (0.18) 7 (0.08) 0 42 (0.18) 4 (0.01) 73 (0.08)
SARS-CoV-2 test positive 155 (2.81) 13 (0.21) 6 (0.07) 0 930 (3.94) 45 (0.09) 1152 (1.19)
Seizure 43 (0.78) 118 (1.89) 67 (0.76) 3 (2.05) 387 (1.64) 1279 (2.43) 1945 (2.01)
Seizure like phenomena 5 (0.09) 7 (0.11) 5 (0.06) 0 27 (0.11) 64 (0.12) 110 (0.11)
Sensation of foreign body 1 (0.02) 8 (0.13) 6 (0.07) 0 27 (0.11) 9 (0.02) 52 (0.05)
Sensitive skin 0 1 (0.02) 20 (0.23) 0 6 (0.03) 92 (0.17) 121 (0.12)
Sensory disturbance 0 4 (0.06) 28 (0.32) 0 39 (0.17) 19 (0.04) 92 (0.09)
Sensory loss 1 (0.02) 11 (0.18) 31 (0.35) 0 29 (0.12) 21 (0.04) 95 (0.10)
Sepsis 98 (1.78) 57 (0.92) 6 (0.07) 0 221 (0.94) 17 (0.03) 412 (0.42)
Septic shock 61 (1.11) 26 (0.42) 0 0 30 (0.13) 2 (0.00) 122 (0.13)
Shock 27 (0.49) 17 (0.27) 1 (0.01) 0 13 (0.06) 23 (0.04) 88 (0.09)
Sinus headache 0 0 4 (0.05) 0 1 (0.00) 72 (0.14) 77 (0.08)
Sinus pain 0 0 12 (0.14) 1 (0.68) 2 (0.01) 57 (0.11) 72 (0.07)
Sinus tachycardia 5 (0.09) 13 (0.21) 10 (0.11) 0 75 (0.32) 10 (0.02) 117 (0.12)
Sinusitis 2 (0.04) 1 (0.02) 14 (0.16) 0 21 (0.09) 30 (0.06) 69 (0.07)
Skin burning sensation 0 7 (0.11) 27 (0.31) 0 23 (0.10) 47 (0.09) 107 (0.11)
Skin discolouration 5 (0.09) 29 (0.47) 34 (0.39) 1 (0.68) 32 (0.14) 28 (0.05) 138 (0.14)
Skin disorder 0 1 (0.02) 134 (1.52) 0 7 (0.03) 18 (0.03) 160 (0.16)
Skin exfoliation 3 (0.05) 6 (0.10) 10 (0.11) 0 18 (0.08) 19 (0.04) 56 (0.06)
Skin reaction 1 (0.02) 7 (0.11) 10 (0.11) 0 14 (0.06) 83 (0.16) 115 (0.12)
Skin warm 4 (0.07) 25 (0.40) 23 (0.26) 0 44 (0.19) 89 (0.17) 185 (0.19)
Sleep disorder 2 (0.04) 41 (0.66) 125 (1.42) 0 97 (0.41) 90 (0.17) 364 (0.38)
Sneezing 1 (0.02) 3 (0.05) 10 (0.11) 0 7 (0.03) 34 (0.06) 55 (0.06)
Somnolence 29 (0.53) 32 (0.51) 82 (0.93) 2 (1.37) 130 (0.55) 250 (0.47) 551 (0.57)
Speech disorder 9 (0.16) 46 (0.74) 63 (0.72) 1 (0.68) 139 (0.59) 35 (0.07) 303 (0.31)
Spinal pain 0 2 (0.03) 24 (0.27) 0 8 (0.03) 23 (0.04) 59 (0.06)
Staphylococcal infection 8 (0.14) 7 (0.11) 2 (0.02) 0 19 (0.08) 23 (0.04) 59 (0.06)
Status epilepticus 1 (0.02) 11 (0.18) 3 (0.03) 0 19 (0.08) 31 (0.06) 66 (0.07)
Subarachnoid haemorrhage 15 (0.27) 39 (0.63) 2 (0.02) 0 38 (0.16) 0 95 (0.10)
Subdural haematoma 11 (0.20) 12 (0.19) 2 (0.02) 0 19 (0.08) 5 (0.01) 52 (0.05)
Sudden death 157 (2.85) 0 0 0 0 0 157 (0.16)
Sudden hearing loss 0 3 (0.05) 64 (0.73) 0 14 (0.06) 111 (0.21) 192 (0.20)
Suicidal ideation 1 (0.02) 17 (0.27) 12 (0.14) 0 12 (0.05) 84 (0.16) 130 (0.13)
Superficial vein thrombosis 1 (0.02) 9 (0.14) 2 (0.02) 0 16 (0.07) 57 (0.11) 87 (0.09)
Supraventricular tachycardia 6 (0.11) 28 (0.45) 13 (0.15) 0 53 (0.22) 18 (0.03) 121 (0.12)
Sweating fever 0 0 3 (0.03) 0 1 (0.00) 49 (0.09) 53 (0.05)
Swelling 11 (0.20) 35 (0.56) 113 (1.29) 0 120 (0.51) 570 (1.08) 854 (0.88)
Swelling face 3 (0.05) 67 (1.08) 45 (0.51) 0 117 (0.50) 183 (0.35) 427 (0.44)
Swollen tongue 2 (0.04) 87 (1.40) 18 (0.20) 0 103 (0.44) 87 (0.17) 303 (0.31)
Syncope 82 (1.49) 200 (3.21) 149 (1.69) 4 (2.74) 672 (2.84) 4284 (8.13) 5488 (5.66)
Systemic inflammatory response syndrome 6 (0.11) 13 (0.21) 1 (0.01) 0 41 (0.17) 18 (0.03) 82 (0.08)
Systemic lupus erythematosus 1 (0.02) 9 (0.14) 11 (0.13) 0 13 (0.06) 57 (0.11) 93 (0.10)
Tachycardia 28 (0.51) 164 (2.63) 151 (1.72) 2 (1.37) 567 (2.40) 700 (1.33) 1629 (1.68)
Tachypnoea 13 (0.24) 14 (0.22) 1 (0.01) 0 93 (0.39) 7 (0.01) 133 (0.14)
Taste disorder 3 (0.05) 9 (0.14) 35 (0.40) 0 27 (0.11) 35 (0.07) 113 (0.12)
Tenderness 2 (0.04) 7 (0.11) 31 (0.35) 0 31 (0.13) 95 (0.18) 168 (0.17)
Tension headache 0 3 (0.05) 22 (0.25) 0 11 (0.05) 116 (0.22) 152 (0.16)
Thirst 0 6 (0.10) 18 (0.20) 0 19 (0.08) 77 (0.15) 123 (0.13)
Throat irritation 0 29 (0.47) 8 (0.09) 0 48 (0.20) 56 (0.11) 142 (0.15)
Throat tightness 2 (0.04) 94 (1.51) 19 (0.22) 0 79 (0.33) 75 (0.14) 275 (0.28)
Thrombocytopenia 30 (0.54) 92 (1.48) 6 (0.07) 0 235 (0.99) 146 (0.28) 533 (0.55)
Thrombophlebitis 0 7 (0.11) 1 (0.01) 0 12 (0.05) 36 (0.07) 56 (0.06)
Thrombosis 60 (1.09) 244 (3.92) 51 (0.58) 2 (1.37) 286 (1.21) 761 (1.44) 1445 (1.49)
Tinnitus 1 (0.02) 33 (0.53) 535 (6.08) 1 (0.68) 82 (0.35) 334 (0.63) 996 (1.03)
Toothache 1 (0.02) 6 (0.10) 10 (0.11) 0 6 (0.03) 30 (0.06) 55 (0.06)
Transient ischaemic attack 8 (0.14) 60 (0.96) 20 (0.23) 0 177 (0.75) 118 (0.22) 394 (0.41)
Tremor 19 (0.34) 100 (1.61) 223 (2.54) 0 283 (1.20) 566 (1.07) 1212 (1.25)
Troponin increased 8 (0.14) 31 (0.50) 2 (0.02) 0 123 (0.52) 9 (0.02) 178 (0.18)
Tunnel vision 0 1 (0.02) 8 (0.09) 0 1 (0.00) 88 (0.17) 100 (0.10)
Unevaluable event 4 (0.07) 13 (0.21) 7 (0.08) 1 (0.68) 439 (1.86) 2 (0.00) 467 (0.48)
Unresponsive to stimuli 188 (3.41) 64 (1.03) 8 (0.09) 0 129 (0.55) 533 (1.01) 994 (1.02)
Urinary incontinence 3 (0.05) 12 (0.19) 20 (0.23) 0 46 (0.19) 18 (0.03) 106 (0.11)
Urinary retention 5 (0.09) 9 (0.14) 8 (0.09) 0 40 (0.17) 41 (0.08) 105 (0.11)
Urinary tract infection 41 (0.74) 27 (0.43) 17 (0.19) 0 202 (0.86) 60 (0.11) 368 (0.38)
Urticaria 0 101 (1.62) 85 (0.97) 2 (1.37) 222 (0.94) 534 (1.01) 955 (0.98)
Uveitis 0 0 10 (0.11) 0 2 (0.01) 53 (0.10) 66 (0.07)
Vaccination complication 17 (0.31) 39 (0.63) 42 (0.48) 0 197 (0.83) 84 (0.16) 391 (0.40)
Vaccination failure 26 (0.47) 20 (0.32) 1 (0.01) 0 108 (0.46) 3195 (6.06) 3358 (3.46)
Vaccination site erythema 0 10 (0.16) 98 (1.11) 0 64 (0.27) 239 (0.45) 416 (0.43)
Vaccination site inflammation 0 0 8 (0.09) 0 6 (0.03) 50 (0.09) 64 (0.07)
Vaccination site movement impairment 0 1 (0.02) 26 (0.30) 0 8 (0.03) 27 (0.05) 64 (0.07)
Vaccination site oedema 0 2 (0.03) 40 (0.45) 0 10 (0.04) 67 (0.13) 119 (0.12)
Vaccination site pain 10 (0.18) 33 (0.53) 245 (2.79) 0 141 (0.60) 490 (0.93) 928 (0.96)
Vaccination site pruritus 0 5 (0.08) 45 (0.51) 0 17 (0.07) 106 (0.20) 173 (0.18)
Vaccination site rash 0 0 11 (0.13) 0 10 (0.04) 87 (0.17) 108 (0.11)
Vaccination site reaction 0 6 (0.10) 12 (0.14) 0 29 (0.12) 73 (0.14) 121 (0.12)
Vaccination site swelling 2 (0.04) 8 (0.13) 57 (0.65) 0 59 (0.25) 184 (0.35) 316 (0.33)
Vaccination site warmth 0 2 (0.03) 30 (0.34) 0 19 (0.08) 107 (0.20) 158 (0.16)
Vaccine breakthrough infection 42 (0.76) 1 (0.02) 2 (0.02) 0 318 (1.35) 89 (0.17) 468 (0.48)
Vaginal haemorrhage 1 (0.02) 17 (0.27) 13 (0.15) 6 (4.11) 40 (0.17) 158 (0.30) 235 (0.24)
Vasculitis 3 (0.05) 10 (0.16) 3 (0.03) 0 29 (0.12) 20 (0.04) 71 (0.07)
Venous thrombosis 1 (0.02) 15 (0.24) 3 (0.03) 0 17 (0.07) 25 (0.05) 66 (0.07)
Venous thrombosis limb 1 (0.02) 9 (0.14) 6 (0.07) 0 22 (0.09) 54 (0.10) 93 (0.10)
Ventricular extrasystoles 1 (0.02) 6 (0.10) 15 (0.17) 0 45 (0.19) 30 (0.06) 100 (0.10)
Ventricular fibrillation 24 (0.43) 29 (0.47) 1 (0.01) 0 15 (0.06) 1 (0.00) 79 (0.08)
Ventricular hypokinesia 1 (0.02) 16 (0.26) 3 (0.03) 0 32 (0.14) 3 (0.01) 57 (0.06)
Ventricular tachycardia 15 (0.27) 37 (0.59) 2 (0.02) 0 48 (0.20) 21 (0.04) 128 (0.13)
Vertigo 3 (0.05) 37 (0.59) 229 (2.60) 0 205 (0.87) 333 (0.63) 819 (0.84)
Vestibular neuronitis 0 2 (0.03) 14 (0.16) 0 48 (0.20) 18 (0.03) 83 (0.09)
Vision blurred 7 (0.13) 37 (0.59) 171 (1.94) 2 (1.37) 162 (0.69) 266 (0.50) 652 (0.67)
Visual field defect 0 5 (0.08) 22 (0.25) 0 23 (0.10) 11 (0.02) 64 (0.07)
Visual impairment 3 (0.05) 32 (0.51) 151 (1.72) 0 153 (0.65) 111 (0.21) 463 (0.48)
Vomiting 133 (2.41) 255 (4.09) 423 (4.81) 2 (1.37) 1136 (4.81) 1620 (3.07) 3658 (3.77)
Walking aid user 7 (0.13) 12 (0.19) 38 (0.43) 0 27 (0.11) 1 (0.00) 88 (0.09)
Weight decreased 9 (0.16) 21 (0.34) 41 (0.47) 0 68 (0.29) 39 (0.07) 184 (0.19)
Weight increased 2 (0.04) 4 (0.06) 13 (0.15) 0 20 (0.08) 11 (0.02) 51 (0.05)
Wheezing 12 (0.22) 42 (0.67) 16 (0.18) 0 104 (0.44) 92 (0.17) 276 (0.28)
White blood cell count increased 9 (0.16) 13 (0.21) 6 (0.07) 0 57 (0.24) 1 (0.00) 89 (0.09)
X-ray 2 (0.04) 16 (0.26) 23 (0.26) 0 10 (0.04) 1 (0.00) 52 (0.05)