Eudravigilance C-19 - Pfizer / Biontech
Liste des effets indésirables (uniquement ceux qui apparaissent dans plus de 50 cas graves)
PT |
Décès 10590 (%) |
Mise en jeu du pronostic vital 13810 (%) |
Invalidité ou incapacité 25725 (%) |
Anomalies congénitales 288 (%) |
Hospitalisation 53479 (%) |
Médicalement significatif 188737 (%) |
Cas Graves 292629 (%) |
---|---|---|---|---|---|---|---|
Abdominal discomfort | 5 (0.05) | 25 (0.18) | 127 (0.49) | 0 | 129 (0.24) | 584 (0.31) | 888 (0.30) |
Abdominal distension | 8 (0.08) | 28 (0.20) | 99 (0.38) | 0 | 80 (0.15) | 414 (0.22) | 642 (0.22) |
Abdominal pain | 62 (0.59) | 136 (0.98) | 411 (1.60) | 5 (1.74) | 853 (1.60) | 1704 (0.90) | 3248 (1.11) |
Abdominal pain lower | 2 (0.02) | 6 (0.04) | 41 (0.16) | 0 | 97 (0.18) | 170 (0.09) | 320 (0.11) |
Abdominal pain upper | 33 (0.31) | 81 (0.59) | 369 (1.43) | 0 | 402 (0.75) | 2059 (1.09) | 2981 (1.02) |
Abnormal behaviour | 3 (0.03) | 4 (0.03) | 9 (0.03) | 0 | 20 (0.04) | 26 (0.01) | 68 (0.02) |
Abnormal dreams | 0 | 1 (0.01) | 16 (0.06) | 0 | 3 (0.01) | 102 (0.05) | 123 (0.04) |
Abnormal faeces | 1 (0.01) | 1 (0.01) | 6 (0.02) | 0 | 41 (0.08) | 19 (0.01) | 68 (0.02) |
Abnormal loss of weight | 1 (0.01) | 6 (0.04) | 16 (0.06) | 0 | 11 (0.02) | 18 (0.01) | 57 (0.02) |
Abortion | 0 | 0 | 0 | 4 (1.39) | 16 (0.03) | 39 (0.02) | 63 (0.02) |
Abortion missed | 1 (0.01) | 3 (0.02) | 1 (0.00) | 4 (1.39) | 19 (0.04) | 72 (0.04) | 100 (0.03) |
Abortion spontaneous | 10 (0.09) | 34 (0.25) | 38 (0.15) | 93 (32.29) | 153 (0.29) | 1159 (0.61) | 1491 (0.51) |
Abscess | 1 (0.01) | 2 (0.01) | 6 (0.02) | 0 | 35 (0.07) | 34 (0.02) | 81 (0.03) |
Acne | 0 | 3 (0.02) | 19 (0.07) | 0 | 9 (0.02) | 109 (0.06) | 140 (0.05) |
Acute coronary syndrome | 33 (0.31) | 54 (0.39) | 3 (0.01) | 0 | 138 (0.26) | 20 (0.01) | 259 (0.09) |
Acute disseminated encephalomyelitis | 5 (0.05) | 6 (0.04) | 15 (0.06) | 0 | 60 (0.11) | 13 (0.01) | 108 (0.04) |
Acute kidney injury | 92 (0.87) | 74 (0.54) | 7 (0.03) | 0 | 170 (0.32) | 65 (0.03) | 450 (0.15) |
Acute myocardial infarction | 180 (1.70) | 234 (1.69) | 9 (0.03) | 0 | 282 (0.53) | 51 (0.03) | 773 (0.26) |
Acute pulmonary oedema | 24 (0.23) | 17 (0.12) | 0 | 0 | 41 (0.08) | 4 (0.00) | 89 (0.03) |
Acute respiratory distress syndrome | 48 (0.45) | 18 (0.13) | 0 | 0 | 15 (0.03) | 5 (0.00) | 101 (0.03) |
Acute respiratory failure | 76 (0.72) | 29 (0.21) | 1 (0.00) | 0 | 43 (0.08) | 11 (0.01) | 170 (0.06) |
Administration site pain | 1 (0.01) | 31 (0.22) | 30 (0.12) | 0 | 3 (0.01) | 35 (0.02) | 100 (0.03) |
Adnexa uteri pain | 0 | 0 | 27 (0.10) | 1 (0.35) | 6 (0.01) | 86 (0.05) | 120 (0.04) |
Ageusia | 2 (0.02) | 19 (0.14) | 162 (0.63) | 0 | 66 (0.12) | 452 (0.24) | 711 (0.24) |
Aggression | 2 (0.02) | 3 (0.02) | 12 (0.05) | 0 | 18 (0.03) | 24 (0.01) | 59 (0.02) |
Agitation | 11 (0.10) | 26 (0.19) | 23 (0.09) | 0 | 60 (0.11) | 116 (0.06) | 244 (0.08) |
Alanine aminotransferase increased | 0 | 6 (0.04) | 10 (0.04) | 0 | 42 (0.08) | 57 (0.03) | 129 (0.04) |
Allergy to vaccine | 1 (0.01) | 15 (0.11) | 7 (0.03) | 0 | 47 (0.09) | 139 (0.07) | 217 (0.07) |
Alopecia | 0 | 9 (0.07) | 102 (0.40) | 0 | 38 (0.07) | 307 (0.16) | 466 (0.16) |
Alopecia areata | 0 | 0 | 16 (0.06) | 0 | 6 (0.01) | 60 (0.03) | 83 (0.03) |
Altered state of consciousness | 47 (0.44) | 39 (0.28) | 21 (0.08) | 0 | 201 (0.38) | 196 (0.10) | 595 (0.20) |
Amenorrhoea | 0 | 18 (0.13) | 184 (0.72) | 6 (2.08) | 34 (0.06) | 600 (0.32) | 848 (0.29) |
Amnesia | 3 (0.03) | 41 (0.30) | 112 (0.44) | 0 | 130 (0.24) | 231 (0.12) | 534 (0.18) |
Anaemia | 20 (0.19) | 65 (0.47) | 47 (0.18) | 0 | 168 (0.31) | 141 (0.07) | 472 (0.16) |
Anal incontinence | 1 (0.01) | 2 (0.01) | 10 (0.04) | 0 | 19 (0.04) | 22 (0.01) | 61 (0.02) |
Anaphylactic reaction | 31 (0.29) | 973 (7.05) | 49 (0.19) | 1 (0.35) | 1603 (3.00) | 3523 (1.87) | 6267 (2.14) |
Anaphylactic shock | 12 (0.11) | 313 (2.27) | 10 (0.04) | 0 | 270 (0.50) | 353 (0.19) | 981 (0.34) |
Anaphylactoid reaction | 1 (0.01) | 16 (0.12) | 2 (0.01) | 0 | 25 (0.05) | 112 (0.06) | 157 (0.05) |
Anger | 1 (0.01) | 4 (0.03) | 10 (0.04) | 0 | 5 (0.01) | 34 (0.02) | 56 (0.02) |
Angina pectoris | 13 (0.12) | 100 (0.72) | 105 (0.41) | 1 (0.35) | 349 (0.65) | 1192 (0.63) | 1812 (0.62) |
Angioedema | 3 (0.03) | 143 (1.04) | 23 (0.09) | 1 (0.35) | 194 (0.36) | 1098 (0.58) | 1496 (0.51) |
Ankylosing spondylitis | 0 | 0 | 10 (0.04) | 0 | 10 (0.02) | 81 (0.04) | 104 (0.04) |
Anosmia | 0 | 17 (0.12) | 136 (0.53) | 0 | 38 (0.07) | 330 (0.17) | 527 (0.18) |
Anovulatory cycle | 0 | 0 | 14 (0.05) | 0 | 1 (0.00) | 35 (0.02) | 51 (0.02) |
Anxiety | 16 (0.15) | 98 (0.71) | 289 (1.12) | 1 (0.35) | 279 (0.52) | 1031 (0.55) | 1746 (0.60) |
Aortic dissection | 59 (0.56) | 28 (0.20) | 1 (0.00) | 0 | 13 (0.02) | 4 (0.00) | 108 (0.04) |
Apathy | 5 (0.05) | 10 (0.07) | 24 (0.09) | 0 | 34 (0.06) | 62 (0.03) | 143 (0.05) |
Aphasia | 25 (0.24) | 94 (0.68) | 77 (0.30) | 0 | 293 (0.55) | 139 (0.07) | 674 (0.23) |
Aphonia | 1 (0.01) | 14 (0.10) | 31 (0.12) | 0 | 34 (0.06) | 144 (0.08) | 229 (0.08) |
Aphthous ulcer | 3 (0.03) | 3 (0.02) | 16 (0.06) | 0 | 15 (0.03) | 74 (0.04) | 112 (0.04) |
Apnoea | 24 (0.23) | 10 (0.07) | 3 (0.01) | 0 | 12 (0.02) | 47 (0.02) | 107 (0.04) |
Appendicitis | 0 | 66 (0.48) | 13 (0.05) | 0 | 281 (0.53) | 103 (0.05) | 466 (0.16) |
Areflexia | 2 (0.02) | 6 (0.04) | 11 (0.04) | 0 | 27 (0.05) | 7 (0.00) | 58 (0.02) |
Arrhythmia | 104 (0.98) | 146 (1.06) | 132 (0.51) | 0 | 862 (1.61) | 1682 (0.89) | 3004 (1.03) |
Arterial occlusive disease | 5 (0.05) | 9 (0.07) | 5 (0.02) | 0 | 38 (0.07) | 13 (0.01) | 72 (0.02) |
Arterial thrombosis | 6 (0.06) | 12 (0.09) | 4 (0.02) | 0 | 19 (0.04) | 10 (0.01) | 53 (0.02) |
Arteriosclerosis | 20 (0.19) | 4 (0.03) | 1 (0.00) | 0 | 21 (0.04) | 2 (0.00) | 54 (0.02) |
Arthralgia | 35 (0.33) | 269 (1.95) | 4146 (16.12) | 3 (1.04) | 1184 (2.21) | 8914 (4.72) | 14665 (5.01) |
Arthritis | 0 | 14 (0.10) | 220 (0.86) | 0 | 96 (0.18) | 430 (0.23) | 770 (0.26) |
Arthritis reactive | 0 | 3 (0.02) | 36 (0.14) | 0 | 22 (0.04) | 114 (0.06) | 179 (0.06) |
Arthropathy | 0 | 2 (0.01) | 37 (0.14) | 0 | 15 (0.03) | 61 (0.03) | 115 (0.04) |
Ascites | 8 (0.08) | 7 (0.05) | 2 (0.01) | 2 (0.69) | 19 (0.04) | 15 (0.01) | 68 (0.02) |
Aspartate aminotransferase increased | 0 | 4 (0.03) | 1 (0.00) | 0 | 33 (0.06) | 37 (0.02) | 85 (0.03) |
Asphyxia | 24 (0.23) | 13 (0.09) | 2 (0.01) | 0 | 9 (0.02) | 45 (0.02) | 101 (0.03) |
Aspiration | 26 (0.25) | 2 (0.01) | 3 (0.01) | 0 | 6 (0.01) | 7 (0.00) | 54 (0.02) |
Asthenia | 212 (2.00) | 342 (2.48) | 1362 (5.29) | 2 (0.69) | 1724 (3.22) | 4604 (2.44) | 8455 (2.89) |
Asthenopia | 0 | 2 (0.01) | 33 (0.13) | 0 | 7 (0.01) | 146 (0.08) | 188 (0.06) |
Asthma | 9 (0.08) | 101 (0.73) | 107 (0.42) | 0 | 257 (0.48) | 695 (0.37) | 1183 (0.40) |
Asthmatic crisis | 0 | 12 (0.09) | 4 (0.02) | 0 | 16 (0.03) | 62 (0.03) | 94 (0.03) |
Asymptomatic COVID-19 | 7 (0.07) | 2 (0.01) | 0 | 0 | 164 (0.31) | 641 (0.34) | 819 (0.28) |
Ataxia | 3 (0.03) | 12 (0.09) | 31 (0.12) | 0 | 60 (0.11) | 23 (0.01) | 140 (0.05) |
Atrial fibrillation | 68 (0.64) | 223 (1.61) | 89 (0.35) | 0 | 793 (1.48) | 862 (0.46) | 2126 (0.73) |
Atrial flutter | 4 (0.04) | 19 (0.14) | 15 (0.06) | 0 | 77 (0.14) | 47 (0.02) | 165 (0.06) |
Atrioventricular block | 5 (0.05) | 20 (0.14) | 5 (0.02) | 0 | 39 (0.07) | 18 (0.01) | 88 (0.03) |
Atrioventricular block complete | 4 (0.04) | 43 (0.31) | 2 (0.01) | 0 | 31 (0.06) | 7 (0.00) | 94 (0.03) |
Auditory disorder | 0 | 2 (0.01) | 12 (0.05) | 0 | 12 (0.02) | 24 (0.01) | 52 (0.02) |
Autoimmune disorder | 5 (0.05) | 15 (0.11) | 47 (0.18) | 0 | 34 (0.06) | 185 (0.10) | 312 (0.11) |
Autoimmune haemolytic anaemia | 5 (0.05) | 18 (0.13) | 4 (0.02) | 0 | 41 (0.08) | 19 (0.01) | 87 (0.03) |
Autoimmune hepatitis | 1 (0.01) | 6 (0.04) | 2 (0.01) | 0 | 46 (0.09) | 29 (0.02) | 85 (0.03) |
Autoimmune thyroiditis | 0 | 1 (0.01) | 7 (0.03) | 0 | 14 (0.03) | 125 (0.07) | 150 (0.05) |
Autonomic nervous system imbalance | 1 (0.01) | 10 (0.07) | 29 (0.11) | 0 | 12 (0.02) | 25 (0.01) | 80 (0.03) |
Axillary mass | 0 | 3 (0.02) | 55 (0.21) | 0 | 8 (0.01) | 249 (0.13) | 318 (0.11) |
Axillary pain | 1 (0.01) | 17 (0.12) | 304 (1.18) | 0 | 56 (0.10) | 2471 (1.31) | 2853 (0.97) |
Back pain | 27 (0.25) | 113 (0.82) | 750 (2.92) | 1 (0.35) | 548 (1.02) | 2457 (1.30) | 3962 (1.35) |
Bacterial infection | 6 (0.06) | 4 (0.03) | 7 (0.03) | 0 | 18 (0.03) | 24 (0.01) | 63 (0.02) |
Balance disorder | 12 (0.11) | 67 (0.49) | 345 (1.34) | 1 (0.35) | 288 (0.54) | 655 (0.35) | 1415 (0.48) |
Basedow's disease | 0 | 5 (0.04) | 17 (0.07) | 0 | 37 (0.07) | 149 (0.08) | 210 (0.07) |
Bedridden | 12 (0.11) | 15 (0.11) | 75 (0.29) | 0 | 26 (0.05) | 93 (0.05) | 237 (0.08) |
Bell's palsy | 1 (0.01) | 12 (0.09) | 258 (1.00) | 3 (1.04) | 299 (0.56) | 2004 (1.06) | 2612 (0.89) |
Blepharospasm | 0 | 3 (0.02) | 28 (0.11) | 0 | 16 (0.03) | 85 (0.05) | 133 (0.05) |
Blindness | 2 (0.02) | 26 (0.19) | 124 (0.48) | 0 | 84 (0.16) | 344 (0.18) | 615 (0.21) |
Blindness transient | 0 | 8 (0.06) | 10 (0.04) | 0 | 22 (0.04) | 119 (0.06) | 162 (0.06) |
Blindness unilateral | 0 | 5 (0.04) | 61 (0.24) | 0 | 26 (0.05) | 81 (0.04) | 191 (0.07) |
Blister | 2 (0.02) | 11 (0.08) | 66 (0.26) | 0 | 72 (0.13) | 406 (0.22) | 570 (0.19) |
Blood creatine phosphokinase increased | 3 (0.03) | 10 (0.07) | 9 (0.03) | 0 | 121 (0.23) | 41 (0.02) | 211 (0.07) |
Blood creatinine increased | 3 (0.03) | 5 (0.04) | 7 (0.03) | 0 | 23 (0.04) | 17 (0.01) | 59 (0.02) |
Blood glucose decreased | 2 (0.02) | 14 (0.10) | 9 (0.03) | 0 | 13 (0.02) | 51 (0.03) | 95 (0.03) |
Blood glucose increased | 6 (0.06) | 24 (0.17) | 23 (0.09) | 0 | 55 (0.10) | 156 (0.08) | 290 (0.10) |
Blood lactate dehydrogenase increased | 2 (0.02) | 5 (0.04) | 1 (0.00) | 0 | 30 (0.06) | 11 (0.01) | 60 (0.02) |
Blood potassium decreased | 0 | 8 (0.06) | 1 (0.00) | 0 | 33 (0.06) | 9 (0.00) | 58 (0.02) |
Blood pressure abnormal | 4 (0.04) | 12 (0.09) | 21 (0.08) | 0 | 33 (0.06) | 85 (0.05) | 160 (0.05) |
Blood pressure decreased | 45 (0.42) | 136 (0.98) | 64 (0.25) | 1 (0.35) | 305 (0.57) | 692 (0.37) | 1315 (0.45) |
Blood pressure fluctuation | 1 (0.01) | 21 (0.15) | 38 (0.15) | 1 (0.35) | 57 (0.11) | 91 (0.05) | 225 (0.08) |
Blood pressure increased | 17 (0.16) | 163 (1.18) | 174 (0.68) | 0 | 793 (1.48) | 2791 (1.48) | 4042 (1.38) |
Blood pressure systolic increased | 0 | 7 (0.05) | 4 (0.02) | 0 | 30 (0.06) | 103 (0.05) | 155 (0.05) |
Blood test abnormal | 1 (0.01) | 3 (0.02) | 7 (0.03) | 0 | 24 (0.04) | 41 (0.02) | 77 (0.03) |
Blood urine present | 2 (0.02) | 11 (0.08) | 13 (0.05) | 0 | 24 (0.04) | 92 (0.05) | 143 (0.05) |
Body temperature | 0 | 2 (0.01) | 8 (0.03) | 0 | 2 (0.00) | 55 (0.03) | 68 (0.02) |
Body temperature abnormal | 0 | 6 (0.04) | 27 (0.10) | 0 | 4 (0.01) | 137 (0.07) | 176 (0.06) |
Body temperature decreased | 5 (0.05) | 9 (0.07) | 20 (0.08) | 0 | 12 (0.02) | 77 (0.04) | 126 (0.04) |
Body temperature fluctuation | 1 (0.01) | 0 | 17 (0.07) | 0 | 12 (0.02) | 76 (0.04) | 106 (0.04) |
Body temperature increased | 17 (0.16) | 10 (0.07) | 74 (0.29) | 0 | 117 (0.22) | 456 (0.24) | 686 (0.23) |
Bone pain | 3 (0.03) | 28 (0.20) | 152 (0.59) | 0 | 53 (0.10) | 512 (0.27) | 757 (0.26) |
Bradycardia | 20 (0.19) | 56 (0.41) | 20 (0.08) | 0 | 127 (0.24) | 518 (0.27) | 783 (0.27) |
Bradykinesia | 1 (0.01) | 7 (0.05) | 7 (0.03) | 0 | 6 (0.01) | 33 (0.02) | 57 (0.02) |
Bradyphrenia | 1 (0.01) | 3 (0.02) | 15 (0.06) | 0 | 7 (0.01) | 46 (0.02) | 73 (0.02) |
Brain injury | 25 (0.24) | 8 (0.06) | 4 (0.02) | 0 | 10 (0.02) | 22 (0.01) | 81 (0.03) |
Brain oedema | 27 (0.25) | 17 (0.12) | 5 (0.02) | 0 | 17 (0.03) | 29 (0.02) | 122 (0.04) |
Brain stem infarction | 7 (0.07) | 20 (0.14) | 7 (0.03) | 0 | 36 (0.07) | 8 (0.00) | 81 (0.03) |
Breast cancer | 0 | 14 (0.10) | 5 (0.02) | 0 | 7 (0.01) | 73 (0.04) | 100 (0.03) |
Breast discomfort | 0 | 0 | 6 (0.02) | 0 | 10 (0.02) | 36 (0.02) | 52 (0.02) |
Breast enlargement | 0 | 4 (0.03) | 5 (0.02) | 0 | 3 (0.01) | 41 (0.02) | 53 (0.02) |
Breast mass | 0 | 5 (0.04) | 14 (0.05) | 1 (0.35) | 8 (0.01) | 106 (0.06) | 137 (0.05) |
Breast pain | 0 | 13 (0.09) | 93 (0.36) | 1 (0.35) | 99 (0.19) | 761 (0.40) | 975 (0.33) |
Breast swelling | 0 | 5 (0.04) | 32 (0.12) | 0 | 14 (0.03) | 197 (0.10) | 249 (0.09) |
Breast tenderness | 0 | 0 | 13 (0.05) | 0 | 3 (0.01) | 88 (0.05) | 105 (0.04) |
Bronchitis | 10 (0.09) | 5 (0.04) | 16 (0.06) | 0 | 31 (0.06) | 78 (0.04) | 149 (0.05) |
Bronchospasm | 5 (0.05) | 61 (0.44) | 5 (0.02) | 0 | 102 (0.19) | 196 (0.10) | 389 (0.13) |
Burning sensation | 4 (0.04) | 54 (0.39) | 238 (0.93) | 0 | 198 (0.37) | 741 (0.39) | 1266 (0.43) |
Bursitis | 0 | 3 (0.02) | 50 (0.19) | 0 | 16 (0.03) | 100 (0.05) | 172 (0.06) |
C-reactive protein increased | 27 (0.25) | 29 (0.21) | 35 (0.14) | 0 | 312 (0.58) | 133 (0.07) | 583 (0.20) |
COVID-19 | 860 (8.12) | 176 (1.27) | 168 (0.65) | 2 (0.69) | 1732 (3.24) | 26555 (14.07) | 29726 (10.16) |
COVID-19 immunisation | 11 (0.10) | 38 (0.28) | 187 (0.73) | 0 | 81 (0.15) | 65 (0.03) | 383 (0.13) |
COVID-19 pneumonia | 245 (2.31) | 85 (0.62) | 9 (0.03) | 0 | 425 (0.79) | 83 (0.04) | 866 (0.30) |
Cardiac arrest | 636 (6.01) | 212 (1.54) | 2 (0.01) | 0 | 65 (0.12) | 46 (0.02) | 1035 (0.35) |
Cardiac death | 54 (0.51) | 0 | 0 | 0 | 1 (0.00) | 0 | 55 (0.02) |
Cardiac discomfort | 3 (0.03) | 14 (0.10) | 29 (0.11) | 0 | 59 (0.11) | 79 (0.04) | 188 (0.06) |
Cardiac disorder | 52 (0.49) | 63 (0.46) | 34 (0.13) | 0 | 132 (0.25) | 161 (0.09) | 459 (0.16) |
Cardiac dysfunction | 5 (0.05) | 8 (0.06) | 2 (0.01) | 0 | 13 (0.02) | 14 (0.01) | 52 (0.02) |
Cardiac failure | 303 (2.86) | 177 (1.28) | 37 (0.14) | 0 | 382 (0.71) | 159 (0.08) | 1114 (0.38) |
Cardiac failure acute | 109 (1.03) | 24 (0.17) | 0 | 0 | 43 (0.08) | 8 (0.00) | 187 (0.06) |
Cardiac failure congestive | 49 (0.46) | 14 (0.10) | 4 (0.02) | 0 | 51 (0.10) | 27 (0.01) | 153 (0.05) |
Cardiac fibrillation | 1 (0.01) | 13 (0.09) | 8 (0.03) | 0 | 34 (0.06) | 45 (0.02) | 107 (0.04) |
Cardiac flutter | 2 (0.02) | 15 (0.11) | 46 (0.18) | 1 (0.35) | 69 (0.13) | 871 (0.46) | 1014 (0.35) |
Cardiac infection | 0 | 5 (0.04) | 5 (0.02) | 0 | 13 (0.02) | 36 (0.02) | 67 (0.02) |
Cardiac murmur | 0 | 4 (0.03) | 5 (0.02) | 1 (0.35) | 14 (0.03) | 33 (0.02) | 59 (0.02) |
Cardiac tamponade | 23 (0.22) | 13 (0.09) | 0 | 0 | 21 (0.04) | 6 (0.00) | 68 (0.02) |
Cardio-respiratory arrest | 416 (3.93) | 70 (0.51) | 0 | 0 | 16 (0.03) | 2 (0.00) | 550 (0.19) |
Cardiogenic shock | 65 (0.61) | 38 (0.28) | 1 (0.00) | 0 | 16 (0.03) | 8 (0.00) | 134 (0.05) |
Cardiomegaly | 23 (0.22) | 15 (0.11) | 9 (0.03) | 1 (0.35) | 37 (0.07) | 33 (0.02) | 128 (0.04) |
Cardiomyopathy | 13 (0.12) | 27 (0.20) | 8 (0.03) | 0 | 53 (0.10) | 52 (0.03) | 168 (0.06) |
Cardiovascular disorder | 39 (0.37) | 34 (0.25) | 55 (0.21) | 0 | 128 (0.24) | 101 (0.05) | 364 (0.12) |
Carditis | 1 (0.01) | 6 (0.04) | 14 (0.05) | 0 | 19 (0.04) | 68 (0.04) | 110 (0.04) |
Carpal tunnel syndrome | 0 | 1 (0.01) | 12 (0.05) | 0 | 5 (0.01) | 48 (0.03) | 67 (0.02) |
Cataract | 0 | 0 | 7 (0.03) | 0 | 7 (0.01) | 60 (0.03) | 75 (0.03) |
Cellulitis | 8 (0.08) | 10 (0.07) | 17 (0.07) | 0 | 82 (0.15) | 473 (0.25) | 608 (0.21) |
Cerebellar haemorrhage | 9 (0.08) | 12 (0.09) | 5 (0.02) | 0 | 16 (0.03) | 5 (0.00) | 51 (0.02) |
Cerebellar infarction | 7 (0.07) | 17 (0.12) | 10 (0.04) | 0 | 56 (0.10) | 12 (0.01) | 105 (0.04) |
Cerebral artery embolism | 11 (0.10) | 16 (0.12) | 5 (0.02) | 0 | 14 (0.03) | 9 (0.00) | 56 (0.02) |
Cerebral haemorrhage | 269 (2.54) | 178 (1.29) | 53 (0.21) | 0 | 268 (0.50) | 60 (0.03) | 862 (0.29) |
Cerebral infarction | 117 (1.10) | 253 (1.83) | 154 (0.60) | 0 | 716 (1.34) | 128 (0.07) | 1419 (0.48) |
Cerebral ischaemia | 14 (0.13) | 23 (0.17) | 17 (0.07) | 0 | 65 (0.12) | 33 (0.02) | 162 (0.06) |
Cerebral thrombosis | 26 (0.25) | 62 (0.45) | 15 (0.06) | 0 | 103 (0.19) | 37 (0.02) | 254 (0.09) |
Cerebral venous sinus thrombosis | 30 (0.28) | 117 (0.85) | 7 (0.03) | 0 | 150 (0.28) | 51 (0.03) | 363 (0.12) |
Cerebral venous thrombosis | 11 (0.10) | 49 (0.35) | 9 (0.03) | 0 | 90 (0.17) | 17 (0.01) | 183 (0.06) |
Cerebrovascular accident | 296 (2.80) | 563 (4.08) | 272 (1.06) | 1 (0.35) | 1331 (2.49) | 634 (0.34) | 3210 (1.10) |
Cerebrovascular disorder | 14 (0.13) | 6 (0.04) | 5 (0.02) | 0 | 17 (0.03) | 10 (0.01) | 53 (0.02) |
Chest discomfort | 40 (0.38) | 267 (1.93) | 443 (1.72) | 3 (1.04) | 1594 (2.98) | 2532 (1.34) | 4970 (1.70) |
Chest pain | 138 (1.30) | 761 (5.51) | 1107 (4.30) | 1 (0.35) | 3501 (6.55) | 5583 (2.96) | 11328 (3.87) |
Chillblains | 0 | 1 (0.01) | 3 (0.01) | 0 | 2 (0.00) | 47 (0.02) | 53 (0.02) |
Chills | 69 (0.65) | 329 (2.38) | 2949 (11.46) | 4 (1.39) | 1298 (2.43) | 7911 (4.19) | 12678 (4.33) |
Choking | 9 (0.08) | 20 (0.14) | 4 (0.02) | 0 | 16 (0.03) | 81 (0.04) | 146 (0.05) |
Choking sensation | 0 | 14 (0.10) | 7 (0.03) | 0 | 20 (0.04) | 42 (0.02) | 88 (0.03) |
Cholecystitis | 4 (0.04) | 5 (0.04) | 4 (0.02) | 0 | 29 (0.05) | 13 (0.01) | 60 (0.02) |
Chromaturia | 0 | 9 (0.07) | 13 (0.05) | 0 | 29 (0.05) | 56 (0.03) | 111 (0.04) |
Chronic fatigue syndrome | 0 | 1 (0.01) | 57 (0.22) | 0 | 19 (0.04) | 79 (0.04) | 159 (0.05) |
Chronic kidney disease | 9 (0.08) | 2 (0.01) | 2 (0.01) | 0 | 21 (0.04) | 13 (0.01) | 52 (0.02) |
Chronic obstructive pulmonary disease | 33 (0.31) | 16 (0.12) | 6 (0.02) | 0 | 58 (0.11) | 36 (0.02) | 161 (0.06) |
Circulatory collapse | 99 (0.93) | 67 (0.49) | 12 (0.05) | 0 | 169 (0.32) | 305 (0.16) | 703 (0.24) |
Cluster headache | 0 | 4 (0.03) | 43 (0.17) | 0 | 19 (0.04) | 170 (0.09) | 236 (0.08) |
Coagulopathy | 21 (0.20) | 37 (0.27) | 28 (0.11) | 0 | 59 (0.11) | 62 (0.03) | 216 (0.07) |
Cognitive disorder | 15 (0.14) | 17 (0.12) | 94 (0.37) | 0 | 56 (0.10) | 140 (0.07) | 341 (0.12) |
Cold sweat | 13 (0.12) | 71 (0.51) | 108 (0.42) | 0 | 244 (0.46) | 789 (0.42) | 1251 (0.43) |
Colitis | 3 (0.03) | 12 (0.09) | 14 (0.05) | 0 | 68 (0.13) | 66 (0.03) | 164 (0.06) |
Colitis ischaemic | 3 (0.03) | 4 (0.03) | 0 | 0 | 43 (0.08) | 28 (0.01) | 79 (0.03) |
Colitis ulcerative | 0 | 9 (0.07) | 31 (0.12) | 0 | 59 (0.11) | 210 (0.11) | 312 (0.11) |
Coma | 54 (0.51) | 52 (0.38) | 6 (0.02) | 0 | 38 (0.07) | 14 (0.01) | 197 (0.07) |
Concomitant disease aggravated | 12 (0.11) | 1 (0.01) | 15 (0.06) | 0 | 11 (0.02) | 22 (0.01) | 63 (0.02) |
Condition aggravated | 98 (0.93) | 100 (0.72) | 420 (1.63) | 0 | 388 (0.73) | 1593 (0.84) | 2679 (0.92) |
Confusional state | 61 (0.58) | 173 (1.25) | 295 (1.15) | 0 | 511 (0.96) | 829 (0.44) | 1931 (0.66) |
Congestive cardiomyopathy | 6 (0.06) | 15 (0.11) | 3 (0.01) | 0 | 34 (0.06) | 7 (0.00) | 70 (0.02) |
Conjunctival haemorrhage | 2 (0.02) | 2 (0.01) | 1 (0.00) | 0 | 10 (0.02) | 177 (0.09) | 196 (0.07) |
Conjunctival hyperaemia | 0 | 2 (0.01) | 2 (0.01) | 0 | 24 (0.04) | 37 (0.02) | 66 (0.02) |
Conjunctivitis | 1 (0.01) | 5 (0.04) | 17 (0.07) | 0 | 28 (0.05) | 80 (0.04) | 131 (0.04) |
Constipation | 5 (0.05) | 9 (0.07) | 66 (0.26) | 0 | 59 (0.11) | 186 (0.10) | 341 (0.12) |
Contusion | 15 (0.14) | 64 (0.46) | 138 (0.54) | 1 (0.35) | 162 (0.30) | 784 (0.42) | 1193 (0.41) |
Conversion disorder | 0 | 0 | 17 (0.07) | 0 | 25 (0.05) | 16 (0.01) | 60 (0.02) |
Coordination abnormal | 5 (0.05) | 12 (0.09) | 48 (0.19) | 1 (0.35) | 54 (0.10) | 65 (0.03) | 192 (0.07) |
Coronary artery disease | 22 (0.21) | 21 (0.15) | 2 (0.01) | 0 | 38 (0.07) | 6 (0.00) | 93 (0.03) |
Coronary artery thrombosis | 15 (0.14) | 25 (0.18) | 0 | 0 | 15 (0.03) | 3 (0.00) | 66 (0.02) |
Costochondritis | 0 | 3 (0.02) | 33 (0.13) | 0 | 34 (0.06) | 83 (0.04) | 156 (0.05) |
Cough | 123 (1.16) | 241 (1.75) | 507 (1.97) | 2 (0.69) | 1125 (2.10) | 2970 (1.57) | 5079 (1.74) |
Crohn's disease | 0 | 3 (0.02) | 17 (0.07) | 0 | 32 (0.06) | 116 (0.06) | 172 (0.06) |
Crying | 0 | 8 (0.06) | 35 (0.14) | 0 | 23 (0.04) | 145 (0.08) | 214 (0.07) |
Cutaneous vasculitis | 1 (0.01) | 4 (0.03) | 1 (0.00) | 0 | 64 (0.12) | 71 (0.04) | 145 (0.05) |
Cyanosis | 39 (0.37) | 53 (0.38) | 22 (0.09) | 0 | 100 (0.19) | 109 (0.06) | 361 (0.12) |
Cyst | 0 | 1 (0.01) | 7 (0.03) | 0 | 9 (0.02) | 35 (0.02) | 53 (0.02) |
Cystitis | 1 (0.01) | 6 (0.04) | 15 (0.06) | 0 | 29 (0.05) | 91 (0.05) | 148 (0.05) |
Deafness | 0 | 18 (0.13) | 169 (0.66) | 0 | 68 (0.13) | 632 (0.33) | 920 (0.31) |
Deafness neurosensory | 0 | 1 (0.01) | 44 (0.17) | 0 | 13 (0.02) | 86 (0.05) | 146 (0.05) |
Deafness unilateral | 0 | 1 (0.01) | 113 (0.44) | 0 | 32 (0.06) | 269 (0.14) | 427 (0.15) |
Death | 1999 (18.88) | 0 | 0 | 0 | 1 (0.00) | 4 (0.00) | 2005 (0.69) |
Decreased appetite | 99 (0.93) | 87 (0.63) | 486 (1.89) | 1 (0.35) | 517 (0.97) | 1672 (0.89) | 2957 (1.01) |
Deep vein thrombosis | 62 (0.59) | 536 (3.88) | 74 (0.29) | 1 (0.35) | 954 (1.78) | 1810 (0.96) | 3520 (1.20) |
Dehydration | 45 (0.42) | 37 (0.27) | 42 (0.16) | 0 | 184 (0.34) | 256 (0.14) | 605 (0.21) |
Delirium | 18 (0.17) | 33 (0.24) | 29 (0.11) | 0 | 85 (0.16) | 226 (0.12) | 429 (0.15) |
Dementia | 14 (0.13) | 3 (0.02) | 21 (0.08) | 0 | 27 (0.05) | 69 (0.04) | 161 (0.06) |
Demyelination | 2 (0.02) | 3 (0.02) | 19 (0.07) | 0 | 43 (0.08) | 33 (0.02) | 113 (0.04) |
Depressed level of consciousness | 85 (0.80) | 92 (0.67) | 30 (0.12) | 0 | 278 (0.52) | 510 (0.27) | 1126 (0.38) |
Depressed mood | 1 (0.01) | 11 (0.08) | 85 (0.33) | 0 | 30 (0.06) | 348 (0.18) | 479 (0.16) |
Depression | 2 (0.02) | 39 (0.28) | 141 (0.55) | 1 (0.35) | 64 (0.12) | 348 (0.18) | 605 (0.21) |
Dermatitis | 1 (0.01) | 7 (0.05) | 22 (0.09) | 0 | 23 (0.04) | 151 (0.08) | 206 (0.07) |
Dermatitis allergic | 0 | 11 (0.08) | 28 (0.11) | 0 | 45 (0.08) | 224 (0.12) | 311 (0.11) |
Dermatitis atopic | 0 | 0 | 17 (0.07) | 1 (0.35) | 10 (0.02) | 48 (0.03) | 76 (0.03) |
Dermatitis bullous | 2 (0.02) | 0 | 10 (0.04) | 0 | 20 (0.04) | 81 (0.04) | 114 (0.04) |
Diabetes mellitus | 9 (0.08) | 13 (0.09) | 16 (0.06) | 0 | 44 (0.08) | 157 (0.08) | 258 (0.09) |
Diabetes mellitus inadequate control | 4 (0.04) | 2 (0.01) | 4 (0.02) | 0 | 10 (0.02) | 75 (0.04) | 99 (0.03) |
Diabetic ketoacidosis | 7 (0.07) | 15 (0.11) | 2 (0.01) | 0 | 17 (0.03) | 18 (0.01) | 65 (0.02) |
Diarrhoea | 105 (0.99) | 184 (1.33) | 950 (3.69) | 3 (1.04) | 1076 (2.01) | 4667 (2.47) | 7116 (2.43) |
Diarrhoea haemorrhagic | 0 | 10 (0.07) | 3 (0.01) | 0 | 30 (0.06) | 92 (0.05) | 139 (0.05) |
Diplegia | 3 (0.03) | 7 (0.05) | 28 (0.11) | 0 | 23 (0.04) | 50 (0.03) | 118 (0.04) |
Diplopia | 2 (0.02) | 20 (0.14) | 127 (0.49) | 0 | 217 (0.41) | 242 (0.13) | 626 (0.21) |
Discomfort | 13 (0.12) | 31 (0.22) | 152 (0.59) | 0 | 171 (0.32) | 701 (0.37) | 1087 (0.37) |
Disease recurrence | 22 (0.21) | 73 (0.53) | 143 (0.56) | 0 | 197 (0.37) | 986 (0.52) | 1456 (0.50) |
Disorientation | 14 (0.13) | 35 (0.25) | 84 (0.33) | 0 | 141 (0.26) | 331 (0.18) | 622 (0.21) |
Disseminated intravascular coagulation | 26 (0.25) | 19 (0.14) | 0 | 0 | 11 (0.02) | 5 (0.00) | 79 (0.03) |
Disturbance in attention | 11 (0.10) | 32 (0.23) | 291 (1.13) | 1 (0.35) | 201 (0.38) | 611 (0.32) | 1175 (0.40) |
Diverticulitis | 2 (0.02) | 3 (0.02) | 5 (0.02) | 0 | 48 (0.09) | 84 (0.04) | 148 (0.05) |
Dizziness | 75 (0.71) | 674 (4.88) | 2216 (8.61) | 6 (2.08) | 3617 (6.76) | 9251 (4.90) | 16086 (5.50) |
Dizziness exertional | 0 | 0 | 12 (0.05) | 0 | 5 (0.01) | 49 (0.03) | 68 (0.02) |
Dizziness postural | 0 | 6 (0.04) | 88 (0.34) | 0 | 42 (0.08) | 563 (0.30) | 701 (0.24) |
Drug eruption | 0 | 2 (0.01) | 2 (0.01) | 0 | 32 (0.06) | 84 (0.04) | 121 (0.04) |
Drug hypersensitivity | 1 (0.01) | 11 (0.08) | 9 (0.03) | 0 | 26 (0.05) | 91 (0.05) | 144 (0.05) |
Drug ineffective | 253 (2.39) | 118 (0.85) | 128 (0.50) | 2 (0.69) | 610 (1.14) | 7885 (4.18) | 9250 (3.16) |
Drug interaction | 5 (0.05) | 6 (0.04) | 7 (0.03) | 0 | 34 (0.06) | 54 (0.03) | 107 (0.04) |
Dry eye | 0 | 3 (0.02) | 46 (0.18) | 0 | 14 (0.03) | 129 (0.07) | 196 (0.07) |
Dry mouth | 1 (0.01) | 37 (0.27) | 76 (0.30) | 0 | 89 (0.17) | 344 (0.18) | 558 (0.19) |
Dry skin | 0 | 6 (0.04) | 32 (0.12) | 0 | 7 (0.01) | 150 (0.08) | 199 (0.07) |
Dry throat | 0 | 4 (0.03) | 26 (0.10) | 0 | 20 (0.04) | 114 (0.06) | 166 (0.06) |
Dysaesthesia | 0 | 9 (0.07) | 25 (0.10) | 0 | 70 (0.13) | 114 (0.06) | 223 (0.08) |
Dysarthria | 30 (0.28) | 69 (0.50) | 104 (0.40) | 1 (0.35) | 327 (0.61) | 180 (0.10) | 755 (0.26) |
Dysentery | 1 (0.01) | 2 (0.01) | 18 (0.07) | 0 | 9 (0.02) | 99 (0.05) | 129 (0.04) |
Dysgeusia | 2 (0.02) | 29 (0.21) | 113 (0.44) | 0 | 114 (0.21) | 585 (0.31) | 853 (0.29) |
Dyskinesia | 4 (0.04) | 12 (0.09) | 48 (0.19) | 1 (0.35) | 91 (0.17) | 120 (0.06) | 286 (0.10) |
Dyslalia | 0 | 3 (0.02) | 9 (0.03) | 0 | 46 (0.09) | 6 (0.00) | 78 (0.03) |
Dysmenorrhoea | 0 | 8 (0.06) | 357 (1.39) | 2 (0.69) | 67 (0.13) | 2815 (1.49) | 3259 (1.11) |
Dyspepsia | 2 (0.02) | 27 (0.20) | 100 (0.39) | 0 | 58 (0.11) | 357 (0.19) | 555 (0.19) |
Dysphagia | 40 (0.38) | 131 (0.95) | 123 (0.48) | 1 (0.35) | 301 (0.56) | 556 (0.29) | 1206 (0.41) |
Dysphemia | 0 | 4 (0.03) | 10 (0.04) | 0 | 19 (0.04) | 19 (0.01) | 55 (0.02) |
Dysphonia | 2 (0.02) | 63 (0.46) | 64 (0.25) | 0 | 176 (0.33) | 356 (0.19) | 693 (0.24) |
Dysphoria | 3 (0.03) | 6 (0.04) | 0 | 0 | 61 (0.11) | 116 (0.06) | 193 (0.07) |
Dyspnoea | 622 (5.87) | 1572 (11.38) | 1553 (6.04) | 6 (2.08) | 4885 (9.13) | 7431 (3.94) | 16633 (5.68) |
Dyspnoea at rest | 1 (0.01) | 9 (0.07) | 6 (0.02) | 0 | 27 (0.05) | 74 (0.04) | 125 (0.04) |
Dyspnoea exertional | 16 (0.15) | 68 (0.49) | 69 (0.27) | 0 | 217 (0.41) | 276 (0.15) | 686 (0.23) |
Dysstasia | 6 (0.06) | 28 (0.20) | 98 (0.38) | 0 | 143 (0.27) | 222 (0.12) | 527 (0.18) |
Dystonia | 0 | 1 (0.01) | 7 (0.03) | 0 | 8 (0.01) | 34 (0.02) | 53 (0.02) |
Dysuria | 6 (0.06) | 9 (0.07) | 23 (0.09) | 0 | 59 (0.11) | 98 (0.05) | 199 (0.07) |
Ear discomfort | 0 | 7 (0.05) | 100 (0.39) | 0 | 53 (0.10) | 211 (0.11) | 384 (0.13) |
Ear disorder | 0 | 2 (0.01) | 22 (0.09) | 1 (0.35) | 7 (0.01) | 32 (0.02) | 66 (0.02) |
Ear infection | 0 | 3 (0.02) | 23 (0.09) | 0 | 11 (0.02) | 109 (0.06) | 150 (0.05) |
Ear pain | 2 (0.02) | 15 (0.11) | 217 (0.84) | 0 | 92 (0.17) | 863 (0.46) | 1208 (0.41) |
Ear swelling | 0 | 3 (0.02) | 8 (0.03) | 0 | 15 (0.03) | 49 (0.03) | 77 (0.03) |
Eating disorder | 6 (0.06) | 9 (0.07) | 19 (0.07) | 0 | 37 (0.07) | 56 (0.03) | 136 (0.05) |
Ecchymosis | 2 (0.02) | 9 (0.07) | 5 (0.02) | 1 (0.35) | 51 (0.10) | 51 (0.03) | 126 (0.04) |
Eczema | 1 (0.01) | 2 (0.01) | 58 (0.23) | 0 | 56 (0.10) | 313 (0.17) | 436 (0.15) |
Ejection fraction decreased | 1 (0.01) | 8 (0.06) | 6 (0.02) | 0 | 27 (0.05) | 9 (0.00) | 63 (0.02) |
Electric shock sensation | 0 | 15 (0.11) | 52 (0.20) | 0 | 19 (0.04) | 61 (0.03) | 148 (0.05) |
Electrocardiogram ST segment elevation | 0 | 5 (0.04) | 1 (0.00) | 0 | 87 (0.16) | 105 (0.06) | 220 (0.08) |
Electrocardiogram abnormal | 0 | 13 (0.09) | 4 (0.02) | 0 | 63 (0.12) | 45 (0.02) | 134 (0.05) |
Embolic stroke | 5 (0.05) | 16 (0.12) | 9 (0.03) | 0 | 49 (0.09) | 12 (0.01) | 95 (0.03) |
Embolism | 28 (0.26) | 42 (0.30) | 25 (0.10) | 0 | 75 (0.14) | 70 (0.04) | 256 (0.09) |
Emotional disorder | 0 | 1 (0.01) | 22 (0.09) | 0 | 6 (0.01) | 71 (0.04) | 100 (0.03) |
Emotional distress | 1 (0.01) | 11 (0.08) | 32 (0.12) | 0 | 16 (0.03) | 72 (0.04) | 135 (0.05) |
Encephalitis | 12 (0.11) | 44 (0.32) | 17 (0.07) | 0 | 127 (0.24) | 30 (0.02) | 242 (0.08) |
Encephalopathy | 10 (0.09) | 9 (0.07) | 7 (0.03) | 0 | 38 (0.07) | 21 (0.01) | 101 (0.03) |
Endocarditis | 10 (0.09) | 11 (0.08) | 1 (0.00) | 0 | 31 (0.06) | 14 (0.01) | 71 (0.02) |
Endometriosis | 0 | 0 | 26 (0.10) | 0 | 18 (0.03) | 103 (0.05) | 148 (0.05) |
Eosinophilia | 0 | 5 (0.04) | 6 (0.02) | 0 | 29 (0.05) | 21 (0.01) | 65 (0.02) |
Epilepsy | 25 (0.24) | 98 (0.71) | 48 (0.19) | 0 | 407 (0.76) | 494 (0.26) | 1097 (0.37) |
Epistaxis | 9 (0.08) | 53 (0.38) | 81 (0.31) | 1 (0.35) | 179 (0.33) | 580 (0.31) | 916 (0.31) |
Epstein-Barr virus infection reactivation | 0 | 2 (0.01) | 4 (0.02) | 0 | 11 (0.02) | 38 (0.02) | 56 (0.02) |
Erectile dysfunction | 0 | 3 (0.02) | 45 (0.17) | 0 | 8 (0.01) | 180 (0.10) | 242 (0.08) |
Eructation | 0 | 3 (0.02) | 14 (0.05) | 0 | 18 (0.03) | 44 (0.02) | 84 (0.03) |
Erysipelas | 5 (0.05) | 3 (0.02) | 5 (0.02) | 0 | 61 (0.11) | 79 (0.04) | 157 (0.05) |
Erythema | 11 (0.10) | 143 (1.04) | 215 (0.84) | 0 | 724 (1.35) | 2561 (1.36) | 3726 (1.27) |
Erythema multiforme | 1 (0.01) | 2 (0.01) | 5 (0.02) | 0 | 65 (0.12) | 190 (0.10) | 270 (0.09) |
Erythema nodosum | 0 | 2 (0.01) | 7 (0.03) | 0 | 27 (0.05) | 61 (0.03) | 98 (0.03) |
Erythema of eyelid | 0 | 1 (0.01) | 4 (0.02) | 0 | 10 (0.02) | 41 (0.02) | 56 (0.02) |
Exercise tolerance decreased | 1 (0.01) | 13 (0.09) | 104 (0.40) | 0 | 61 (0.11) | 71 (0.04) | 262 (0.09) |
Exposure during pregnancy | 2 (0.02) | 11 (0.08) | 2 (0.01) | 3 (1.04) | 29 (0.05) | 96 (0.05) | 147 (0.05) |
Exposure via breast milk | 2 (0.02) | 2 (0.01) | 4 (0.02) | 2 (0.69) | 19 (0.04) | 175 (0.09) | 205 (0.07) |
Extensive swelling of vaccinated limb | 2 (0.02) | 10 (0.07) | 332 (1.29) | 0 | 14 (0.03) | 86 (0.05) | 444 (0.15) |
Extrasystoles | 2 (0.02) | 33 (0.24) | 73 (0.28) | 0 | 122 (0.23) | 291 (0.15) | 527 (0.18) |
Eye disorder | 1 (0.01) | 4 (0.03) | 34 (0.13) | 0 | 51 (0.10) | 112 (0.06) | 203 (0.07) |
Eye haemorrhage | 1 (0.01) | 4 (0.03) | 18 (0.07) | 0 | 14 (0.03) | 252 (0.13) | 297 (0.10) |
Eye inflammation | 0 | 0 | 22 (0.09) | 0 | 13 (0.02) | 49 (0.03) | 86 (0.03) |
Eye irritation | 0 | 8 (0.06) | 34 (0.13) | 0 | 11 (0.02) | 142 (0.08) | 198 (0.07) |
Eye movement disorder | 1 (0.01) | 15 (0.11) | 26 (0.10) | 0 | 46 (0.09) | 59 (0.03) | 156 (0.05) |
Eye oedema | 0 | 4 (0.03) | 11 (0.04) | 0 | 9 (0.02) | 36 (0.02) | 61 (0.02) |
Eye pain | 1 (0.01) | 37 (0.27) | 260 (1.01) | 0 | 147 (0.27) | 1058 (0.56) | 1525 (0.52) |
Eye pruritus | 0 | 14 (0.10) | 33 (0.13) | 0 | 33 (0.06) | 239 (0.13) | 328 (0.11) |
Eye swelling | 0 | 38 (0.28) | 58 (0.23) | 1 (0.35) | 63 (0.12) | 537 (0.28) | 708 (0.24) |
Eyelid oedema | 0 | 11 (0.08) | 8 (0.03) | 0 | 54 (0.10) | 152 (0.08) | 231 (0.08) |
Eyelid ptosis | 1 (0.01) | 7 (0.05) | 21 (0.08) | 0 | 50 (0.09) | 79 (0.04) | 167 (0.06) |
Face oedema | 2 (0.02) | 40 (0.29) | 26 (0.10) | 0 | 116 (0.22) | 277 (0.15) | 472 (0.16) |
Facial asymmetry | 0 | 1 (0.01) | 4 (0.02) | 0 | 25 (0.05) | 22 (0.01) | 53 (0.02) |
Facial pain | 0 | 4 (0.03) | 68 (0.26) | 0 | 50 (0.09) | 269 (0.14) | 397 (0.14) |
Facial paralysis | 5 (0.05) | 54 (0.39) | 234 (0.91) | 2 (0.69) | 743 (1.39) | 2189 (1.16) | 3290 (1.12) |
Facial paresis | 1 (0.01) | 29 (0.21) | 93 (0.36) | 0 | 318 (0.59) | 333 (0.18) | 790 (0.27) |
Facial spasm | 0 | 5 (0.04) | 17 (0.07) | 0 | 5 (0.01) | 33 (0.02) | 60 (0.02) |
Faeces discoloured | 4 (0.04) | 5 (0.04) | 10 (0.04) | 0 | 17 (0.03) | 39 (0.02) | 81 (0.03) |
Fall | 99 (0.93) | 99 (0.72) | 124 (0.48) | 0 | 459 (0.86) | 611 (0.32) | 1530 (0.52) |
Fatigue | 212 (2.00) | 720 (5.21) | 6691 (26.01) | 10 (3.47) | 2833 (5.30) | 17547 (9.30) | 28270 (9.66) |
Fear | 1 (0.01) | 7 (0.05) | 17 (0.07) | 0 | 12 (0.02) | 66 (0.03) | 105 (0.04) |
Febrile convulsion | 1 (0.01) | 4 (0.03) | 5 (0.02) | 1 (0.35) | 35 (0.07) | 39 (0.02) | 85 (0.03) |
Feeding disorder | 6 (0.06) | 16 (0.12) | 59 (0.23) | 0 | 52 (0.10) | 147 (0.08) | 303 (0.10) |
Feeling abnormal | 16 (0.15) | 120 (0.87) | 598 (2.32) | 1 (0.35) | 539 (1.01) | 2356 (1.25) | 3722 (1.27) |
Feeling cold | 6 (0.06) | 48 (0.35) | 252 (0.98) | 0 | 181 (0.34) | 1367 (0.72) | 1875 (0.64) |
Feeling drunk | 1 (0.01) | 3 (0.02) | 15 (0.06) | 1 (0.35) | 9 (0.02) | 88 (0.05) | 118 (0.04) |
Feeling hot | 4 (0.04) | 92 (0.67) | 218 (0.85) | 1 (0.35) | 390 (0.73) | 1562 (0.83) | 2303 (0.79) |
Feeling jittery | 1 (0.01) | 2 (0.01) | 5 (0.02) | 0 | 22 (0.04) | 42 (0.02) | 76 (0.03) |
Feeling of body temperature change | 1 (0.01) | 13 (0.09) | 96 (0.37) | 0 | 63 (0.12) | 451 (0.24) | 625 (0.21) |
Fibrin D dimer increased | 14 (0.13) | 43 (0.31) | 20 (0.08) | 0 | 210 (0.39) | 205 (0.11) | 525 (0.18) |
Fibromyalgia | 1 (0.01) | 6 (0.04) | 87 (0.34) | 0 | 14 (0.03) | 135 (0.07) | 246 (0.08) |
Fine motor skill dysfunction | 1 (0.01) | 2 (0.01) | 17 (0.07) | 0 | 14 (0.03) | 16 (0.01) | 52 (0.02) |
Flank pain | 2 (0.02) | 4 (0.03) | 22 (0.09) | 0 | 38 (0.07) | 73 (0.04) | 142 (0.05) |
Flatulence | 1 (0.01) | 7 (0.05) | 33 (0.13) | 0 | 18 (0.03) | 138 (0.07) | 200 (0.07) |
Fluid retention | 6 (0.06) | 9 (0.07) | 14 (0.05) | 1 (0.35) | 21 (0.04) | 48 (0.03) | 104 (0.04) |
Flushing | 1 (0.01) | 57 (0.41) | 40 (0.16) | 0 | 183 (0.34) | 544 (0.29) | 841 (0.29) |
Foetal death | 22 (0.21) | 4 (0.03) | 2 (0.01) | 6 (2.08) | 29 (0.05) | 46 (0.02) | 112 (0.04) |
Foetal exposure during pregnancy | 16 (0.15) | 7 (0.05) | 1 (0.00) | 13 (4.51) | 5 (0.01) | 7 (0.00) | 53 (0.02) |
Foetal growth restriction | 16 (0.15) | 3 (0.02) | 1 (0.00) | 10 (3.47) | 3 (0.01) | 25 (0.01) | 62 (0.02) |
Food allergy | 0 | 20 (0.14) | 14 (0.05) | 0 | 9 (0.02) | 38 (0.02) | 84 (0.03) |
Formication | 0 | 4 (0.03) | 26 (0.10) | 1 (0.35) | 12 (0.02) | 122 (0.06) | 169 (0.06) |
Fracture | 1 (0.01) | 2 (0.01) | 3 (0.01) | 0 | 20 (0.04) | 24 (0.01) | 53 (0.02) |
Gait disturbance | 20 (0.19) | 100 (0.72) | 530 (2.06) | 0 | 528 (0.99) | 835 (0.44) | 2118 (0.72) |
Gait inability | 8 (0.08) | 33 (0.24) | 212 (0.82) | 0 | 156 (0.29) | 247 (0.13) | 705 (0.24) |
Gamma-glutamyltransferase increased | 0 | 2 (0.01) | 3 (0.01) | 0 | 20 (0.04) | 20 (0.01) | 51 (0.02) |
Gastric disorder | 2 (0.02) | 2 (0.01) | 9 (0.03) | 0 | 7 (0.01) | 31 (0.02) | 53 (0.02) |
Gastritis | 1 (0.01) | 2 (0.01) | 24 (0.09) | 0 | 36 (0.07) | 56 (0.03) | 123 (0.04) |
Gastroenteritis | 2 (0.02) | 4 (0.03) | 3 (0.01) | 0 | 51 (0.10) | 38 (0.02) | 101 (0.03) |
Gastrointestinal disorder | 4 (0.04) | 8 (0.06) | 42 (0.16) | 0 | 58 (0.11) | 113 (0.06) | 234 (0.08) |
Gastrointestinal haemorrhage | 34 (0.32) | 19 (0.14) | 1 (0.00) | 0 | 37 (0.07) | 30 (0.02) | 131 (0.04) |
Gastrointestinal pain | 0 | 10 (0.07) | 44 (0.17) | 0 | 45 (0.08) | 132 (0.07) | 236 (0.08) |
Gastrooesophageal reflux disease | 2 (0.02) | 11 (0.08) | 52 (0.20) | 0 | 35 (0.07) | 133 (0.07) | 235 (0.08) |
Gaze palsy | 4 (0.04) | 5 (0.04) | 4 (0.02) | 0 | 18 (0.03) | 26 (0.01) | 63 (0.02) |
General physical health deterioration | 222 (2.10) | 51 (0.37) | 67 (0.26) | 0 | 260 (0.49) | 85 (0.05) | 754 (0.26) |
Generalised oedema | 8 (0.08) | 7 (0.05) | 7 (0.03) | 0 | 26 (0.05) | 36 (0.02) | 92 (0.03) |
Generalised tonic-clonic seizure | 8 (0.08) | 47 (0.34) | 10 (0.04) | 0 | 171 (0.32) | 200 (0.11) | 447 (0.15) |
Genital haemorrhage | 0 | 1 (0.01) | 1 (0.00) | 0 | 9 (0.02) | 69 (0.04) | 81 (0.03) |
Genital herpes | 0 | 0 | 17 (0.07) | 0 | 14 (0.03) | 79 (0.04) | 110 (0.04) |
Giant cell arteritis | 2 (0.02) | 10 (0.07) | 15 (0.06) | 0 | 70 (0.13) | 43 (0.02) | 141 (0.05) |
Gingival bleeding | 0 | 13 (0.09) | 11 (0.04) | 0 | 31 (0.06) | 66 (0.03) | 122 (0.04) |
Gingival pain | 0 | 2 (0.01) | 16 (0.06) | 0 | 4 (0.01) | 88 (0.05) | 111 (0.04) |
Gingival swelling | 1 (0.01) | 3 (0.02) | 12 (0.05) | 0 | 2 (0.00) | 45 (0.02) | 64 (0.02) |
Glaucoma | 0 | 1 (0.01) | 6 (0.02) | 0 | 9 (0.02) | 40 (0.02) | 59 (0.02) |
Glossodynia | 0 | 4 (0.03) | 31 (0.12) | 0 | 14 (0.03) | 131 (0.07) | 180 (0.06) |
Goitre | 1 (0.01) | 1 (0.01) | 9 (0.03) | 0 | 12 (0.02) | 30 (0.02) | 56 (0.02) |
Gout | 0 | 3 (0.02) | 31 (0.12) | 0 | 22 (0.04) | 80 (0.04) | 138 (0.05) |
Grip strength decreased | 1 (0.01) | 1 (0.01) | 37 (0.14) | 0 | 21 (0.04) | 69 (0.04) | 131 (0.04) |
Groin pain | 4 (0.04) | 6 (0.04) | 50 (0.19) | 0 | 30 (0.06) | 128 (0.07) | 225 (0.08) |
Guillain-Barre syndrome | 22 (0.21) | 99 (0.72) | 104 (0.40) | 0 | 571 (1.07) | 280 (0.15) | 1120 (0.38) |
Haematemesis | 38 (0.36) | 17 (0.12) | 12 (0.05) | 0 | 47 (0.09) | 86 (0.05) | 216 (0.07) |
Haematochezia | 7 (0.07) | 8 (0.06) | 22 (0.09) | 1 (0.35) | 75 (0.14) | 351 (0.19) | 478 (0.16) |
Haematoma | 13 (0.12) | 41 (0.30) | 61 (0.24) | 1 (0.35) | 117 (0.22) | 203 (0.11) | 448 (0.15) |
Haematuria | 4 (0.04) | 18 (0.13) | 11 (0.04) | 0 | 82 (0.15) | 143 (0.08) | 268 (0.09) |
Haemoglobin decreased | 7 (0.07) | 17 (0.12) | 8 (0.03) | 0 | 58 (0.11) | 35 (0.02) | 137 (0.05) |
Haemolytic anaemia | 5 (0.05) | 13 (0.09) | 2 (0.01) | 0 | 28 (0.05) | 11 (0.01) | 62 (0.02) |
Haemophagocytic lymphohistiocytosis | 8 (0.08) | 14 (0.10) | 0 | 0 | 19 (0.04) | 7 (0.00) | 51 (0.02) |
Haemoptysis | 16 (0.15) | 34 (0.25) | 20 (0.08) | 0 | 66 (0.12) | 85 (0.05) | 237 (0.08) |
Haemorrhage | 25 (0.24) | 66 (0.48) | 80 (0.31) | 8 (2.78) | 149 (0.28) | 1567 (0.83) | 1945 (0.66) |
Haemorrhage intracranial | 20 (0.19) | 17 (0.12) | 1 (0.00) | 0 | 20 (0.04) | 5 (0.00) | 70 (0.02) |
Haemorrhage subcutaneous | 3 (0.03) | 1 (0.01) | 2 (0.01) | 0 | 13 (0.02) | 170 (0.09) | 206 (0.07) |
Haemorrhage urinary tract | 1 (0.01) | 2 (0.01) | 3 (0.01) | 0 | 4 (0.01) | 57 (0.03) | 70 (0.02) |
Haemorrhagic diathesis | 1 (0.01) | 4 (0.03) | 1 (0.00) | 0 | 13 (0.02) | 27 (0.01) | 55 (0.02) |
Haemorrhagic stroke | 64 (0.60) | 31 (0.22) | 8 (0.03) | 0 | 31 (0.06) | 11 (0.01) | 147 (0.05) |
Haemorrhoids | 1 (0.01) | 0 | 9 (0.03) | 0 | 7 (0.01) | 44 (0.02) | 62 (0.02) |
Hallucination | 7 (0.07) | 29 (0.21) | 57 (0.22) | 0 | 55 (0.10) | 455 (0.24) | 625 (0.21) |
Hallucination, auditory | 0 | 3 (0.02) | 6 (0.02) | 0 | 13 (0.02) | 46 (0.02) | 70 (0.02) |
Hallucination, visual | 1 (0.01) | 6 (0.04) | 10 (0.04) | 0 | 19 (0.04) | 90 (0.05) | 129 (0.04) |
Hangover | 0 | 0 | 20 (0.08) | 0 | 3 (0.01) | 60 (0.03) | 83 (0.03) |
Head discomfort | 0 | 36 (0.26) | 152 (0.59) | 1 (0.35) | 156 (0.29) | 441 (0.23) | 805 (0.28) |
Head injury | 4 (0.04) | 18 (0.13) | 10 (0.04) | 0 | 62 (0.12) | 130 (0.07) | 242 (0.08) |
Headache | 135 (1.27) | 863 (6.25) | 6468 (25.14) | 8 (2.78) | 4598 (8.60) | 21739 (11.52) | 34173 (11.68) |
Heart rate | 0 | 2 (0.01) | 17 (0.07) | 0 | 18 (0.03) | 78 (0.04) | 115 (0.04) |
Heart rate abnormal | 0 | 16 (0.12) | 29 (0.11) | 0 | 42 (0.08) | 149 (0.08) | 239 (0.08) |
Heart rate decreased | 6 (0.06) | 43 (0.31) | 33 (0.13) | 1 (0.35) | 96 (0.18) | 276 (0.15) | 482 (0.16) |
Heart rate increased | 21 (0.20) | 226 (1.64) | 379 (1.47) | 0 | 668 (1.25) | 1663 (0.88) | 3038 (1.04) |
Heart rate irregular | 1 (0.01) | 41 (0.30) | 83 (0.32) | 1 (0.35) | 127 (0.24) | 319 (0.17) | 581 (0.20) |
Heavy menstrual bleeding | 0 | 47 (0.34) | 529 (2.06) | 7 (2.43) | 205 (0.38) | 4485 (2.38) | 5296 (1.81) |
Hemianaesthesia | 0 | 9 (0.07) | 24 (0.09) | 0 | 55 (0.10) | 54 (0.03) | 144 (0.05) |
Hemiparaesthesia | 1 (0.01) | 1 (0.01) | 12 (0.05) | 0 | 47 (0.09) | 117 (0.06) | 181 (0.06) |
Hemiparesis | 45 (0.42) | 89 (0.64) | 104 (0.40) | 0 | 356 (0.67) | 248 (0.13) | 908 (0.31) |
Hemiplegia | 21 (0.20) | 45 (0.33) | 55 (0.21) | 0 | 146 (0.27) | 87 (0.05) | 413 (0.14) |
Henoch-Schonlein purpura | 1 (0.01) | 1 (0.01) | 5 (0.02) | 0 | 38 (0.07) | 23 (0.01) | 69 (0.02) |
Hepatic cytolysis | 1 (0.01) | 2 (0.01) | 0 | 0 | 44 (0.08) | 48 (0.03) | 97 (0.03) |
Hepatic enzyme increased | 4 (0.04) | 9 (0.07) | 5 (0.02) | 0 | 58 (0.11) | 36 (0.02) | 119 (0.04) |
Hepatic failure | 22 (0.21) | 9 (0.07) | 1 (0.00) | 0 | 15 (0.03) | 7 (0.00) | 61 (0.02) |
Hepatic function abnormal | 6 (0.06) | 11 (0.08) | 4 (0.02) | 0 | 89 (0.17) | 39 (0.02) | 156 (0.05) |
Hepatitis | 4 (0.04) | 4 (0.03) | 4 (0.02) | 0 | 59 (0.11) | 67 (0.04) | 146 (0.05) |
Hepatitis acute | 4 (0.04) | 5 (0.04) | 1 (0.00) | 0 | 46 (0.09) | 22 (0.01) | 81 (0.03) |
Herpes ophthalmic | 0 | 0 | 3 (0.01) | 0 | 6 (0.01) | 69 (0.04) | 79 (0.03) |
Herpes simplex | 0 | 1 (0.01) | 7 (0.03) | 0 | 16 (0.03) | 54 (0.03) | 78 (0.03) |
Herpes virus infection | 0 | 1 (0.01) | 14 (0.05) | 0 | 8 (0.01) | 44 (0.02) | 69 (0.02) |
Herpes zoster | 15 (0.14) | 36 (0.26) | 317 (1.23) | 1 (0.35) | 543 (1.02) | 2572 (1.36) | 3506 (1.20) |
Herpes zoster oticus | 0 | 3 (0.02) | 11 (0.04) | 0 | 40 (0.07) | 67 (0.04) | 124 (0.04) |
Hormone level abnormal | 1 (0.01) | 2 (0.01) | 24 (0.09) | 0 | 7 (0.01) | 90 (0.05) | 124 (0.04) |
Hospitalisation | 2 (0.02) | 5 (0.04) | 1 (0.00) | 0 | 93 (0.17) | 1 (0.00) | 127 (0.04) |
Hot flush | 1 (0.01) | 20 (0.14) | 156 (0.61) | 0 | 126 (0.24) | 871 (0.46) | 1185 (0.40) |
Hyperacusis | 0 | 4 (0.03) | 64 (0.25) | 1 (0.35) | 32 (0.06) | 95 (0.05) | 199 (0.07) |
Hyperaesthesia | 0 | 2 (0.01) | 59 (0.23) | 0 | 21 (0.04) | 162 (0.09) | 247 (0.08) |
Hyperglycaemia | 7 (0.07) | 17 (0.12) | 12 (0.05) | 0 | 38 (0.07) | 106 (0.06) | 188 (0.06) |
Hyperhidrosis | 24 (0.23) | 180 (1.30) | 481 (1.87) | 2 (0.69) | 518 (0.97) | 2422 (1.28) | 3682 (1.26) |
Hyperpyrexia | 24 (0.23) | 15 (0.11) | 11 (0.04) | 0 | 82 (0.15) | 643 (0.34) | 782 (0.27) |
Hypersensitivity | 10 (0.09) | 326 (2.36) | 181 (0.70) | 2 (0.69) | 694 (1.30) | 1765 (0.94) | 3043 (1.04) |
Hypersomnia | 3 (0.03) | 14 (0.10) | 87 (0.34) | 0 | 27 (0.05) | 270 (0.14) | 412 (0.14) |
Hypertension | 49 (0.46) | 323 (2.34) | 248 (0.96) | 2 (0.69) | 1128 (2.11) | 2825 (1.50) | 4715 (1.61) |
Hypertensive crisis | 10 (0.09) | 49 (0.35) | 11 (0.04) | 0 | 203 (0.38) | 477 (0.25) | 766 (0.26) |
Hyperthermia | 9 (0.08) | 8 (0.06) | 13 (0.05) | 0 | 39 (0.07) | 72 (0.04) | 147 (0.05) |
Hyperthyroidism | 1 (0.01) | 9 (0.07) | 26 (0.10) | 0 | 35 (0.07) | 194 (0.10) | 269 (0.09) |
Hyperventilation | 1 (0.01) | 22 (0.16) | 16 (0.06) | 0 | 149 (0.28) | 196 (0.10) | 396 (0.14) |
Hypoacusis | 1 (0.01) | 12 (0.09) | 180 (0.70) | 0 | 68 (0.13) | 316 (0.17) | 583 (0.20) |
Hypoaesthesia | 11 (0.10) | 292 (2.11) | 1199 (4.66) | 4 (1.39) | 1446 (2.70) | 3332 (1.77) | 6415 (2.19) |
Hypoaesthesia oral | 2 (0.02) | 64 (0.46) | 85 (0.33) | 1 (0.35) | 165 (0.31) | 527 (0.28) | 865 (0.30) |
Hypoglycaemia | 7 (0.07) | 27 (0.20) | 11 (0.04) | 1 (0.35) | 35 (0.07) | 131 (0.07) | 215 (0.07) |
Hypokalaemia | 5 (0.05) | 15 (0.11) | 4 (0.02) | 0 | 47 (0.09) | 30 (0.02) | 125 (0.04) |
Hypokinesia | 3 (0.03) | 13 (0.09) | 127 (0.49) | 1 (0.35) | 56 (0.10) | 259 (0.14) | 473 (0.16) |
Hypomenorrhoea | 0 | 0 | 40 (0.16) | 1 (0.35) | 6 (0.01) | 284 (0.15) | 331 (0.11) |
Hyponatraemia | 6 (0.06) | 22 (0.16) | 6 (0.02) | 0 | 49 (0.09) | 2 (0.00) | 93 (0.03) |
Hypophagia | 19 (0.18) | 3 (0.02) | 7 (0.03) | 0 | 39 (0.07) | 34 (0.02) | 114 (0.04) |
Hypopnoea | 5 (0.05) | 17 (0.12) | 19 (0.07) | 0 | 21 (0.04) | 110 (0.06) | 185 (0.06) |
Hypotension | 84 (0.79) | 209 (1.51) | 110 (0.43) | 1 (0.35) | 447 (0.84) | 897 (0.48) | 1843 (0.63) |
Hypothermia | 10 (0.09) | 14 (0.10) | 9 (0.03) | 0 | 17 (0.03) | 144 (0.08) | 205 (0.07) |
Hypothyroidism | 0 | 3 (0.02) | 26 (0.10) | 0 | 16 (0.03) | 133 (0.07) | 187 (0.06) |
Hypotonia | 7 (0.07) | 11 (0.08) | 21 (0.08) | 0 | 77 (0.14) | 71 (0.04) | 194 (0.07) |
Hypotonic-hyporesponsive episode | 6 (0.06) | 1 (0.01) | 0 | 0 | 15 (0.03) | 46 (0.02) | 69 (0.02) |
Hypovolaemic shock | 8 (0.08) | 3 (0.02) | 0 | 0 | 8 (0.01) | 61 (0.03) | 85 (0.03) |
Hypoxia | 55 (0.52) | 45 (0.33) | 4 (0.02) | 0 | 100 (0.19) | 86 (0.05) | 352 (0.12) |
IIIrd nerve paralysis | 0 | 2 (0.01) | 3 (0.01) | 0 | 24 (0.04) | 27 (0.01) | 59 (0.02) |
Illness | 13 (0.12) | 66 (0.48) | 267 (1.04) | 3 (1.04) | 210 (0.39) | 1578 (0.84) | 2168 (0.74) |
Immobile | 3 (0.03) | 5 (0.04) | 23 (0.09) | 0 | 9 (0.02) | 49 (0.03) | 98 (0.03) |
Immune system disorder | 4 (0.04) | 4 (0.03) | 28 (0.11) | 0 | 24 (0.04) | 80 (0.04) | 153 (0.05) |
Immune thrombocytopenia | 13 (0.12) | 134 (0.97) | 4 (0.02) | 0 | 299 (0.56) | 213 (0.11) | 674 (0.23) |
Immunisation | 120 (1.13) | 329 (2.38) | 1113 (4.33) | 7 (2.43) | 779 (1.46) | 12489 (6.62) | 14936 (5.10) |
Immunisation reaction | 0 | 0 | 5 (0.02) | 0 | 36 (0.07) | 149 (0.08) | 200 (0.07) |
Immunodeficiency | 0 | 1 (0.01) | 8 (0.03) | 0 | 4 (0.01) | 66 (0.03) | 88 (0.03) |
Impaired driving ability | 0 | 5 (0.04) | 40 (0.16) | 0 | 9 (0.02) | 42 (0.02) | 101 (0.03) |
Impaired quality of life | 0 | 7 (0.05) | 38 (0.15) | 0 | 5 (0.01) | 50 (0.03) | 104 (0.04) |
Impaired work ability | 0 | 23 (0.17) | 286 (1.11) | 0 | 71 (0.13) | 282 (0.15) | 696 (0.24) |
Inappropriate schedule of product administration | 4 (0.04) | 8 (0.06) | 58 (0.23) | 3 (1.04) | 39 (0.07) | 410 (0.22) | 544 (0.19) |
Incontinence | 5 (0.05) | 16 (0.12) | 21 (0.08) | 0 | 27 (0.05) | 30 (0.02) | 109 (0.04) |
Increased tendency to bruise | 0 | 3 (0.02) | 13 (0.05) | 0 | 7 (0.01) | 37 (0.02) | 60 (0.02) |
Induration | 0 | 0 | 4 (0.02) | 0 | 23 (0.04) | 52 (0.03) | 80 (0.03) |
Infarction | 20 (0.19) | 31 (0.22) | 8 (0.03) | 0 | 32 (0.06) | 13 (0.01) | 110 (0.04) |
Infection | 30 (0.28) | 22 (0.16) | 43 (0.17) | 1 (0.35) | 123 (0.23) | 227 (0.12) | 469 (0.16) |
Infectious mononucleosis | 0 | 5 (0.04) | 11 (0.04) | 0 | 17 (0.03) | 32 (0.02) | 65 (0.02) |
Inflammation | 10 (0.09) | 46 (0.33) | 187 (0.73) | 0 | 270 (0.50) | 543 (0.29) | 1104 (0.38) |
Inflammatory marker increased | 4 (0.04) | 7 (0.05) | 7 (0.03) | 0 | 57 (0.11) | 21 (0.01) | 105 (0.04) |
Influenza | 1 (0.01) | 21 (0.15) | 176 (0.68) | 0 | 216 (0.40) | 1170 (0.62) | 1593 (0.54) |
Influenza like illness | 23 (0.22) | 40 (0.29) | 584 (2.27) | 1 (0.35) | 413 (0.77) | 2846 (1.51) | 3954 (1.35) |
Initial insomnia | 0 | 2 (0.01) | 12 (0.05) | 0 | 11 (0.02) | 39 (0.02) | 65 (0.02) |
Injected limb mobility decreased | 0 | 3 (0.02) | 66 (0.26) | 0 | 4 (0.01) | 133 (0.07) | 206 (0.07) |
Injection site erythema | 3 (0.03) | 2 (0.01) | 35 (0.14) | 0 | 31 (0.06) | 100 (0.05) | 173 (0.06) |
Injection site pain | 4 (0.04) | 18 (0.13) | 294 (1.14) | 0 | 215 (0.40) | 503 (0.27) | 1036 (0.35) |
Injection site reaction | 2 (0.02) | 22 (0.16) | 1392 (5.41) | 0 | 59 (0.11) | 84 (0.04) | 1560 (0.53) |
Injection site swelling | 3 (0.03) | 1 (0.01) | 41 (0.16) | 0 | 45 (0.08) | 55 (0.03) | 145 (0.05) |
Injury | 2 (0.02) | 4 (0.03) | 9 (0.03) | 0 | 23 (0.04) | 39 (0.02) | 79 (0.03) |
Insomnia | 11 (0.10) | 99 (0.72) | 659 (2.56) | 1 (0.35) | 241 (0.45) | 2190 (1.16) | 3234 (1.11) |
Interchange of vaccine products | 58 (0.55) | 190 (1.38) | 716 (2.78) | 2 (0.69) | 415 (0.78) | 7882 (4.18) | 9319 (3.18) |
Intermenstrual bleeding | 0 | 5 (0.04) | 96 (0.37) | 1 (0.35) | 51 (0.10) | 863 (0.46) | 1024 (0.35) |
Internal haemorrhage | 8 (0.08) | 9 (0.07) | 3 (0.01) | 0 | 17 (0.03) | 144 (0.08) | 192 (0.07) |
International normalised ratio increased | 6 (0.06) | 9 (0.07) | 3 (0.01) | 0 | 23 (0.04) | 54 (0.03) | 104 (0.04) |
Interstitial lung disease | 47 (0.44) | 24 (0.17) | 9 (0.03) | 0 | 81 (0.15) | 36 (0.02) | 214 (0.07) |
Intestinal haemorrhage | 4 (0.04) | 4 (0.03) | 0 | 0 | 24 (0.04) | 19 (0.01) | 53 (0.02) |
Intestinal ischaemia | 40 (0.38) | 12 (0.09) | 1 (0.00) | 0 | 23 (0.04) | 9 (0.00) | 90 (0.03) |
Intestinal obstruction | 13 (0.12) | 6 (0.04) | 0 | 0 | 23 (0.04) | 20 (0.01) | 63 (0.02) |
Intracardiac thrombus | 17 (0.16) | 11 (0.08) | 1 (0.00) | 0 | 21 (0.04) | 7 (0.00) | 62 (0.02) |
Intracranial aneurysm | 13 (0.12) | 12 (0.09) | 1 (0.00) | 0 | 12 (0.02) | 7 (0.00) | 52 (0.02) |
Intracranial pressure increased | 4 (0.04) | 7 (0.05) | 9 (0.03) | 0 | 16 (0.03) | 31 (0.02) | 74 (0.03) |
Iridocyclitis | 0 | 0 | 7 (0.03) | 0 | 9 (0.02) | 73 (0.04) | 92 (0.03) |
Irritability | 4 (0.04) | 4 (0.03) | 33 (0.13) | 0 | 36 (0.07) | 211 (0.11) | 290 (0.10) |
Irritable bowel syndrome | 0 | 3 (0.02) | 32 (0.12) | 0 | 5 (0.01) | 79 (0.04) | 120 (0.04) |
Ischaemia | 8 (0.08) | 19 (0.14) | 16 (0.06) | 0 | 35 (0.07) | 20 (0.01) | 100 (0.03) |
Ischaemic cerebral infarction | 12 (0.11) | 32 (0.23) | 10 (0.04) | 0 | 49 (0.09) | 11 (0.01) | 116 (0.04) |
Ischaemic stroke | 85 (0.80) | 185 (1.34) | 92 (0.36) | 0 | 671 (1.25) | 59 (0.03) | 1100 (0.38) |
Jaundice | 12 (0.11) | 11 (0.08) | 5 (0.02) | 1 (0.35) | 72 (0.13) | 36 (0.02) | 144 (0.05) |
Joint effusion | 0 | 0 | 16 (0.06) | 0 | 8 (0.01) | 33 (0.02) | 58 (0.02) |
Joint range of motion decreased | 1 (0.01) | 5 (0.04) | 118 (0.46) | 1 (0.35) | 26 (0.05) | 374 (0.20) | 537 (0.18) |
Joint stiffness | 0 | 6 (0.04) | 103 (0.40) | 0 | 26 (0.05) | 264 (0.14) | 403 (0.14) |
Joint swelling | 2 (0.02) | 25 (0.18) | 249 (0.97) | 0 | 124 (0.23) | 612 (0.32) | 1030 (0.35) |
Jugular vein thrombosis | 1 (0.01) | 12 (0.09) | 0 | 0 | 25 (0.05) | 17 (0.01) | 55 (0.02) |
Kidney infection | 1 (0.01) | 8 (0.06) | 9 (0.03) | 0 | 20 (0.04) | 81 (0.04) | 125 (0.04) |
Labyrinthitis | 0 | 1 (0.01) | 32 (0.12) | 0 | 14 (0.03) | 91 (0.05) | 139 (0.05) |
Lacrimation increased | 0 | 11 (0.08) | 41 (0.16) | 0 | 39 (0.07) | 183 (0.10) | 282 (0.10) |
Lacunar infarction | 1 (0.01) | 7 (0.05) | 0 | 0 | 37 (0.07) | 15 (0.01) | 67 (0.02) |
Language disorder | 1 (0.01) | 5 (0.04) | 12 (0.05) | 0 | 79 (0.15) | 15 (0.01) | 121 (0.04) |
Laryngeal oedema | 3 (0.03) | 63 (0.46) | 0 | 0 | 56 (0.10) | 196 (0.10) | 331 (0.11) |
Laryngospasm | 1 (0.01) | 12 (0.09) | 1 (0.00) | 0 | 20 (0.04) | 37 (0.02) | 71 (0.02) |
Left ventricular dysfunction | 4 (0.04) | 12 (0.09) | 3 (0.01) | 0 | 24 (0.04) | 4 (0.00) | 54 (0.02) |
Lethargy | 33 (0.31) | 62 (0.45) | 292 (1.14) | 0 | 268 (0.50) | 1545 (0.82) | 2221 (0.76) |
Leukocytosis | 5 (0.05) | 11 (0.08) | 1 (0.00) | 0 | 34 (0.06) | 12 (0.01) | 69 (0.02) |
Leukopenia | 6 (0.06) | 6 (0.04) | 4 (0.02) | 0 | 27 (0.05) | 65 (0.03) | 114 (0.04) |
Limb discomfort | 2 (0.02) | 34 (0.25) | 283 (1.10) | 0 | 426 (0.80) | 1220 (0.65) | 1996 (0.68) |
Limb injury | 1 (0.01) | 2 (0.01) | 62 (0.24) | 1 (0.35) | 12 (0.02) | 102 (0.05) | 183 (0.06) |
Limb mass | 0 | 1 (0.01) | 14 (0.05) | 0 | 3 (0.01) | 61 (0.03) | 80 (0.03) |
Lip oedema | 1 (0.01) | 9 (0.07) | 6 (0.02) | 0 | 48 (0.09) | 148 (0.08) | 216 (0.07) |
Lip pain | 0 | 1 (0.01) | 8 (0.03) | 0 | 4 (0.01) | 61 (0.03) | 76 (0.03) |
Lip pruritus | 0 | 7 (0.05) | 1 (0.00) | 0 | 11 (0.02) | 53 (0.03) | 73 (0.02) |
Lip swelling | 1 (0.01) | 124 (0.90) | 53 (0.21) | 0 | 173 (0.32) | 742 (0.39) | 1109 (0.38) |
Livedo reticularis | 5 (0.05) | 4 (0.03) | 6 (0.02) | 0 | 7 (0.01) | 31 (0.02) | 56 (0.02) |
Liver disorder | 6 (0.06) | 13 (0.09) | 15 (0.06) | 0 | 53 (0.10) | 32 (0.02) | 126 (0.04) |
Liver function test abnormal | 3 (0.03) | 4 (0.03) | 7 (0.03) | 0 | 32 (0.06) | 35 (0.02) | 86 (0.03) |
Liver function test increased | 0 | 2 (0.01) | 5 (0.02) | 0 | 22 (0.04) | 28 (0.01) | 59 (0.02) |
Liver injury | 0 | 3 (0.02) | 3 (0.01) | 0 | 26 (0.05) | 35 (0.02) | 74 (0.03) |
Local reaction | 5 (0.05) | 12 (0.09) | 52 (0.20) | 0 | 37 (0.07) | 70 (0.04) | 176 (0.06) |
Localised infection | 1 (0.01) | 4 (0.03) | 9 (0.03) | 0 | 12 (0.02) | 34 (0.02) | 63 (0.02) |
Localised oedema | 0 | 17 (0.12) | 21 (0.08) | 0 | 31 (0.06) | 83 (0.04) | 154 (0.05) |
Loss of consciousness | 178 (1.68) | 371 (2.69) | 147 (0.57) | 2 (0.69) | 829 (1.55) | 3154 (1.67) | 4978 (1.70) |
Loss of control of legs | 0 | 3 (0.02) | 9 (0.03) | 0 | 18 (0.03) | 35 (0.02) | 71 (0.02) |
Loss of personal independence in daily activities | 3 (0.03) | 40 (0.29) | 352 (1.37) | 0 | 77 (0.14) | 443 (0.23) | 959 (0.33) |
Lower respiratory tract infection | 21 (0.20) | 21 (0.15) | 41 (0.16) | 0 | 40 (0.07) | 274 (0.15) | 413 (0.14) |
Lung disorder | 23 (0.22) | 21 (0.15) | 19 (0.07) | 0 | 75 (0.14) | 58 (0.03) | 211 (0.07) |
Lung infiltration | 7 (0.07) | 5 (0.04) | 0 | 0 | 29 (0.05) | 11 (0.01) | 58 (0.02) |
Lyme disease | 0 | 2 (0.01) | 7 (0.03) | 0 | 5 (0.01) | 48 (0.03) | 66 (0.02) |
Lymph node pain | 1 (0.01) | 8 (0.06) | 154 (0.60) | 0 | 50 (0.09) | 1505 (0.80) | 1728 (0.59) |
Lymphadenitis | 1 (0.01) | 13 (0.09) | 30 (0.12) | 0 | 50 (0.09) | 245 (0.13) | 343 (0.12) |
Lymphadenopathy | 16 (0.15) | 124 (0.90) | 1065 (4.14) | 8 (2.78) | 592 (1.11) | 7369 (3.90) | 9228 (3.15) |
Lymphangitis | 0 | 0 | 2 (0.01) | 0 | 13 (0.02) | 43 (0.02) | 58 (0.02) |
Lymphoedema | 0 | 6 (0.04) | 22 (0.09) | 0 | 10 (0.02) | 133 (0.07) | 173 (0.06) |
Lymphoma | 7 (0.07) | 15 (0.11) | 2 (0.01) | 0 | 13 (0.02) | 79 (0.04) | 122 (0.04) |
Lymphopenia | 3 (0.03) | 6 (0.04) | 2 (0.01) | 0 | 23 (0.04) | 22 (0.01) | 56 (0.02) |
Macular oedema | 0 | 0 | 16 (0.06) | 0 | 6 (0.01) | 32 (0.02) | 60 (0.02) |
Malaise | 289 (2.73) | 517 (3.74) | 2688 (10.45) | 3 (1.04) | 2144 (4.01) | 6232 (3.30) | 12120 (4.14) |
Mass | 0 | 4 (0.03) | 18 (0.07) | 0 | 10 (0.02) | 119 (0.06) | 158 (0.05) |
Mastitis | 0 | 0 | 9 (0.03) | 0 | 11 (0.02) | 181 (0.10) | 202 (0.07) |
Maternal exposure during breast feeding | 0 | 2 (0.01) | 21 (0.08) | 2 (0.69) | 16 (0.03) | 190 (0.10) | 233 (0.08) |
Maternal exposure during pregnancy | 46 (0.43) | 40 (0.29) | 31 (0.12) | 37 (12.85) | 87 (0.16) | 422 (0.22) | 683 (0.23) |
Melaena | 10 (0.09) | 7 (0.05) | 0 | 0 | 30 (0.06) | 36 (0.02) | 90 (0.03) |
Memory impairment | 4 (0.04) | 26 (0.19) | 171 (0.66) | 0 | 128 (0.24) | 251 (0.13) | 610 (0.21) |
Meniere's disease | 0 | 2 (0.01) | 26 (0.10) | 0 | 21 (0.04) | 58 (0.03) | 108 (0.04) |
Meningitis | 2 (0.02) | 12 (0.09) | 7 (0.03) | 0 | 71 (0.13) | 38 (0.02) | 138 (0.05) |
Meningitis aseptic | 0 | 6 (0.04) | 1 (0.00) | 0 | 65 (0.12) | 13 (0.01) | 87 (0.03) |
Menometrorrhagia | 0 | 4 (0.03) | 14 (0.05) | 0 | 14 (0.03) | 51 (0.03) | 84 (0.03) |
Menstrual disorder | 0 | 22 (0.16) | 285 (1.11) | 1 (0.35) | 99 (0.19) | 1415 (0.75) | 1833 (0.63) |
Menstruation delayed | 0 | 8 (0.06) | 199 (0.77) | 4 (1.39) | 21 (0.04) | 1858 (0.98) | 2094 (0.72) |
Menstruation irregular | 0 | 17 (0.12) | 257 (1.00) | 5 (1.74) | 74 (0.14) | 1950 (1.03) | 2312 (0.79) |
Mental disorder | 1 (0.01) | 7 (0.05) | 26 (0.10) | 0 | 23 (0.04) | 41 (0.02) | 102 (0.03) |
Mental fatigue | 1 (0.01) | 8 (0.06) | 81 (0.31) | 0 | 11 (0.02) | 143 (0.08) | 245 (0.08) |
Mental impairment | 4 (0.04) | 18 (0.13) | 39 (0.15) | 0 | 23 (0.04) | 274 (0.15) | 384 (0.13) |
Mesenteric vein thrombosis | 9 (0.08) | 22 (0.16) | 2 (0.01) | 0 | 50 (0.09) | 13 (0.01) | 97 (0.03) |
Micturition urgency | 1 (0.01) | 0 | 10 (0.04) | 0 | 16 (0.03) | 57 (0.03) | 90 (0.03) |
Middle insomnia | 0 | 4 (0.03) | 27 (0.10) | 0 | 12 (0.02) | 74 (0.04) | 118 (0.04) |
Migraine | 5 (0.05) | 82 (0.59) | 754 (2.93) | 1 (0.35) | 328 (0.61) | 2563 (1.36) | 3762 (1.29) |
Migraine with aura | 0 | 1 (0.01) | 49 (0.19) | 0 | 33 (0.06) | 190 (0.10) | 276 (0.09) |
Miliaria | 0 | 0 | 6 (0.02) | 0 | 3 (0.01) | 58 (0.03) | 67 (0.02) |
Mitral valve incompetence | 3 (0.03) | 5 (0.04) | 2 (0.01) | 0 | 23 (0.04) | 16 (0.01) | 65 (0.02) |
Mobility decreased | 11 (0.10) | 30 (0.22) | 262 (1.02) | 0 | 135 (0.25) | 382 (0.20) | 857 (0.29) |
Monoparesis | 2 (0.02) | 16 (0.12) | 32 (0.12) | 0 | 76 (0.14) | 104 (0.06) | 242 (0.08) |
Monoplegia | 6 (0.06) | 17 (0.12) | 79 (0.31) | 0 | 80 (0.15) | 249 (0.13) | 449 (0.15) |
Mood altered | 0 | 5 (0.04) | 13 (0.05) | 0 | 7 (0.01) | 62 (0.03) | 88 (0.03) |
Mood swings | 0 | 1 (0.01) | 25 (0.10) | 0 | 6 (0.01) | 103 (0.05) | 136 (0.05) |
Motion sickness | 0 | 2 (0.01) | 16 (0.06) | 0 | 2 (0.00) | 57 (0.03) | 78 (0.03) |
Motor dysfunction | 6 (0.06) | 7 (0.05) | 39 (0.15) | 0 | 92 (0.17) | 51 (0.03) | 200 (0.07) |
Mouth haemorrhage | 4 (0.04) | 12 (0.09) | 3 (0.01) | 0 | 27 (0.05) | 21 (0.01) | 78 (0.03) |
Mouth swelling | 3 (0.03) | 27 (0.20) | 11 (0.04) | 0 | 32 (0.06) | 117 (0.06) | 192 (0.07) |
Mouth ulceration | 1 (0.01) | 4 (0.03) | 26 (0.10) | 0 | 12 (0.02) | 213 (0.11) | 257 (0.09) |
Movement disorder | 10 (0.09) | 27 (0.20) | 135 (0.52) | 1 (0.35) | 204 (0.38) | 299 (0.16) | 718 (0.25) |
Multiple organ dysfunction syndrome | 125 (1.18) | 21 (0.15) | 0 | 0 | 13 (0.02) | 12 (0.01) | 195 (0.07) |
Multiple sclerosis | 1 (0.01) | 3 (0.02) | 56 (0.22) | 0 | 81 (0.15) | 170 (0.09) | 327 (0.11) |
Multiple sclerosis relapse | 1 (0.01) | 4 (0.03) | 39 (0.15) | 0 | 71 (0.13) | 159 (0.08) | 276 (0.09) |
Multisystem inflammatory syndrome in children | 0 | 21 (0.15) | 0 | 0 | 24 (0.04) | 5 (0.00) | 51 (0.02) |
Muscle atrophy | 1 (0.01) | 7 (0.05) | 23 (0.09) | 0 | 10 (0.02) | 23 (0.01) | 68 (0.02) |
Muscle contractions involuntary | 1 (0.01) | 10 (0.07) | 35 (0.14) | 0 | 38 (0.07) | 54 (0.03) | 139 (0.05) |
Muscle fatigue | 0 | 3 (0.02) | 71 (0.28) | 0 | 13 (0.02) | 261 (0.14) | 351 (0.12) |
Muscle injury | 0 | 3 (0.02) | 11 (0.04) | 0 | 6 (0.01) | 32 (0.02) | 52 (0.02) |
Muscle rigidity | 3 (0.03) | 9 (0.07) | 37 (0.14) | 0 | 25 (0.05) | 47 (0.02) | 126 (0.04) |
Muscle spasms | 8 (0.08) | 92 (0.67) | 451 (1.75) | 0 | 355 (0.66) | 1602 (0.85) | 2559 (0.87) |
Muscle spasticity | 1 (0.01) | 2 (0.01) | 16 (0.06) | 0 | 14 (0.03) | 20 (0.01) | 54 (0.02) |
Muscle strain | 0 | 1 (0.01) | 18 (0.07) | 0 | 11 (0.02) | 50 (0.03) | 81 (0.03) |
Muscle swelling | 0 | 0 | 6 (0.02) | 0 | 7 (0.01) | 41 (0.02) | 55 (0.02) |
Muscle tightness | 0 | 7 (0.05) | 48 (0.19) | 0 | 56 (0.10) | 154 (0.08) | 271 (0.09) |
Muscle twitching | 4 (0.04) | 32 (0.23) | 145 (0.56) | 0 | 126 (0.24) | 366 (0.19) | 682 (0.23) |
Muscular weakness | 27 (0.25) | 122 (0.88) | 786 (3.06) | 0 | 777 (1.45) | 1301 (0.69) | 3104 (1.06) |
Musculoskeletal chest pain | 1 (0.01) | 19 (0.14) | 64 (0.25) | 0 | 70 (0.13) | 314 (0.17) | 476 (0.16) |
Musculoskeletal discomfort | 1 (0.01) | 7 (0.05) | 42 (0.16) | 0 | 41 (0.08) | 140 (0.07) | 239 (0.08) |
Musculoskeletal disorder | 1 (0.01) | 7 (0.05) | 45 (0.17) | 0 | 21 (0.04) | 52 (0.03) | 132 (0.05) |
Musculoskeletal pain | 1 (0.01) | 19 (0.14) | 109 (0.42) | 0 | 134 (0.25) | 383 (0.20) | 658 (0.22) |
Musculoskeletal stiffness | 5 (0.05) | 39 (0.28) | 430 (1.67) | 0 | 171 (0.32) | 1217 (0.64) | 1891 (0.65) |
Myalgia | 64 (0.60) | 319 (2.31) | 4757 (18.49) | 4 (1.39) | 1471 (2.75) | 8951 (4.74) | 15686 (5.36) |
Myasthenia gravis | 2 (0.02) | 3 (0.02) | 16 (0.06) | 0 | 44 (0.08) | 41 (0.02) | 109 (0.04) |
Mydriasis | 3 (0.03) | 8 (0.06) | 2 (0.01) | 0 | 17 (0.03) | 32 (0.02) | 67 (0.02) |
Myelitis | 4 (0.04) | 4 (0.03) | 40 (0.16) | 1 (0.35) | 146 (0.27) | 42 (0.02) | 242 (0.08) |
Myelitis transverse | 1 (0.01) | 9 (0.07) | 44 (0.17) | 0 | 74 (0.14) | 39 (0.02) | 175 (0.06) |
Myocardial infarction | 456 (4.31) | 406 (2.94) | 46 (0.18) | 0 | 584 (1.09) | 343 (0.18) | 1911 (0.65) |
Myocardial injury | 0 | 15 (0.11) | 2 (0.01) | 0 | 21 (0.04) | 18 (0.01) | 67 (0.02) |
Myocardial ischaemia | 73 (0.69) | 7 (0.05) | 3 (0.01) | 0 | 20 (0.04) | 21 (0.01) | 131 (0.04) |
Myocardial necrosis marker increased | 1 (0.01) | 3 (0.02) | 2 (0.01) | 0 | 44 (0.08) | 12 (0.01) | 75 (0.03) |
Myocarditis | 101 (0.95) | 693 (5.02) | 299 (1.16) | 3 (1.04) | 3758 (7.03) | 3582 (1.90) | 8563 (2.93) |
Myoclonus | 2 (0.02) | 11 (0.08) | 22 (0.09) | 0 | 40 (0.07) | 49 (0.03) | 130 (0.04) |
Myositis | 4 (0.04) | 8 (0.06) | 30 (0.12) | 0 | 60 (0.11) | 62 (0.03) | 166 (0.06) |
Nasal congestion | 1 (0.01) | 12 (0.09) | 83 (0.32) | 0 | 47 (0.09) | 418 (0.22) | 563 (0.19) |
Nasal discomfort | 0 | 2 (0.01) | 11 (0.04) | 0 | 8 (0.01) | 50 (0.03) | 71 (0.02) |
Nasopharyngitis | 26 (0.25) | 25 (0.18) | 150 (0.58) | 2 (0.69) | 131 (0.24) | 910 (0.48) | 1258 (0.43) |
Nausea | 118 (1.11) | 496 (3.59) | 3397 (13.21) | 4 (1.39) | 2695 (5.04) | 11794 (6.25) | 18722 (6.40) |
Near death experience | 0 | 31 (0.22) | 4 (0.02) | 0 | 7 (0.01) | 104 (0.06) | 164 (0.06) |
Neck mass | 0 | 4 (0.03) | 10 (0.04) | 0 | 4 (0.01) | 49 (0.03) | 68 (0.02) |
Neck pain | 6 (0.06) | 72 (0.52) | 525 (2.04) | 1 (0.35) | 363 (0.68) | 1925 (1.02) | 2933 (1.00) |
Neoplasm malignant | 14 (0.13) | 12 (0.09) | 1 (0.00) | 0 | 15 (0.03) | 70 (0.04) | 120 (0.04) |
Nephritis | 1 (0.01) | 4 (0.03) | 1 (0.00) | 0 | 20 (0.04) | 33 (0.02) | 61 (0.02) |
Nephrolithiasis | 0 | 3 (0.02) | 3 (0.01) | 0 | 27 (0.05) | 68 (0.04) | 109 (0.04) |
Nephrotic syndrome | 2 (0.02) | 7 (0.05) | 6 (0.02) | 0 | 106 (0.20) | 74 (0.04) | 201 (0.07) |
Nerve compression | 1 (0.01) | 1 (0.01) | 9 (0.03) | 0 | 3 (0.01) | 46 (0.02) | 62 (0.02) |
Nerve injury | 2 (0.02) | 8 (0.06) | 74 (0.29) | 0 | 16 (0.03) | 81 (0.04) | 187 (0.06) |
Nervous system disorder | 25 (0.24) | 30 (0.22) | 100 (0.39) | 0 | 100 (0.19) | 84 (0.04) | 357 (0.12) |
Nervousness | 0 | 16 (0.12) | 41 (0.16) | 0 | 26 (0.05) | 204 (0.11) | 289 (0.10) |
Neuralgia | 2 (0.02) | 21 (0.15) | 317 (1.23) | 0 | 219 (0.41) | 619 (0.33) | 1201 (0.41) |
Neuralgic amyotrophy | 0 | 0 | 52 (0.20) | 0 | 30 (0.06) | 68 (0.04) | 150 (0.05) |
Neuritis | 0 | 1 (0.01) | 17 (0.07) | 0 | 37 (0.07) | 37 (0.02) | 94 (0.03) |
Neurological symptom | 2 (0.02) | 10 (0.07) | 51 (0.20) | 1 (0.35) | 57 (0.11) | 69 (0.04) | 194 (0.07) |
Neuropathy peripheral | 0 | 10 (0.07) | 145 (0.56) | 0 | 100 (0.19) | 814 (0.43) | 1113 (0.38) |
Neutropenia | 2 (0.02) | 14 (0.10) | 2 (0.01) | 0 | 31 (0.06) | 82 (0.04) | 138 (0.05) |
Night sweats | 3 (0.03) | 15 (0.11) | 112 (0.44) | 1 (0.35) | 75 (0.14) | 578 (0.31) | 793 (0.27) |
Nightmare | 0 | 7 (0.05) | 33 (0.13) | 0 | 8 (0.01) | 133 (0.07) | 184 (0.06) |
Nodule | 1 (0.01) | 10 (0.07) | 21 (0.08) | 0 | 31 (0.06) | 73 (0.04) | 140 (0.05) |
Nuchal rigidity | 0 | 1 (0.01) | 11 (0.04) | 0 | 13 (0.02) | 35 (0.02) | 61 (0.02) |
Nystagmus | 1 (0.01) | 4 (0.03) | 10 (0.04) | 0 | 50 (0.09) | 28 (0.01) | 101 (0.03) |
Obstructive airways disorder | 5 (0.05) | 20 (0.14) | 2 (0.01) | 0 | 32 (0.06) | 37 (0.02) | 99 (0.03) |
Ocular discomfort | 0 | 8 (0.06) | 24 (0.09) | 0 | 43 (0.08) | 98 (0.05) | 173 (0.06) |
Ocular hyperaemia | 0 | 15 (0.11) | 34 (0.13) | 0 | 61 (0.11) | 299 (0.16) | 422 (0.14) |
Odynophagia | 0 | 1 (0.01) | 22 (0.09) | 0 | 37 (0.07) | 140 (0.07) | 203 (0.07) |
Oedema | 10 (0.09) | 37 (0.27) | 43 (0.17) | 1 (0.35) | 154 (0.29) | 286 (0.15) | 551 (0.19) |
Oedema peripheral | 32 (0.30) | 61 (0.44) | 109 (0.42) | 0 | 239 (0.45) | 423 (0.22) | 901 (0.31) |
Off label use | 67 (0.63) | 216 (1.56) | 805 (3.13) | 2 (0.69) | 512 (0.96) | 8902 (4.72) | 10579 (3.62) |
Oligomenorrhoea | 0 | 1 (0.01) | 48 (0.19) | 0 | 14 (0.03) | 174 (0.09) | 237 (0.08) |
Ophthalmic herpes zoster | 0 | 3 (0.02) | 23 (0.09) | 0 | 58 (0.11) | 290 (0.15) | 379 (0.13) |
Ophthalmic vein thrombosis | 1 (0.01) | 1 (0.01) | 9 (0.03) | 0 | 33 (0.06) | 51 (0.03) | 95 (0.03) |
Optic ischaemic neuropathy | 0 | 0 | 24 (0.09) | 0 | 32 (0.06) | 30 (0.02) | 88 (0.03) |
Optic neuritis | 0 | 0 | 49 (0.19) | 0 | 126 (0.24) | 108 (0.06) | 289 (0.10) |
Oral discomfort | 0 | 11 (0.08) | 24 (0.09) | 0 | 28 (0.05) | 96 (0.05) | 160 (0.05) |
Oral herpes | 0 | 6 (0.04) | 32 (0.12) | 0 | 18 (0.03) | 236 (0.13) | 295 (0.10) |
Oral mucosal blistering | 0 | 1 (0.01) | 14 (0.05) | 0 | 11 (0.02) | 33 (0.02) | 62 (0.02) |
Oral pain | 1 (0.01) | 2 (0.01) | 31 (0.12) | 0 | 18 (0.03) | 122 (0.06) | 178 (0.06) |
Oral pruritus | 0 | 10 (0.07) | 7 (0.03) | 0 | 29 (0.05) | 60 (0.03) | 108 (0.04) |
Organising pneumonia | 7 (0.07) | 3 (0.02) | 4 (0.02) | 0 | 26 (0.05) | 15 (0.01) | 58 (0.02) |
Oropharyngeal discomfort | 0 | 27 (0.20) | 25 (0.10) | 0 | 249 (0.47) | 547 (0.29) | 867 (0.30) |
Oropharyngeal pain | 16 (0.15) | 71 (0.51) | 377 (1.47) | 3 (1.04) | 346 (0.65) | 2082 (1.10) | 2920 (1.00) |
Orthostatic hypotension | 0 | 4 (0.03) | 7 (0.03) | 0 | 25 (0.05) | 41 (0.02) | 82 (0.03) |
Osteoarthritis | 0 | 1 (0.01) | 37 (0.14) | 0 | 8 (0.01) | 65 (0.03) | 115 (0.04) |
Ovarian cyst | 0 | 0 | 12 (0.05) | 0 | 23 (0.04) | 25 (0.01) | 61 (0.02) |
Overdose | 0 | 2 (0.01) | 4 (0.02) | 0 | 20 (0.04) | 44 (0.02) | 72 (0.02) |
Ovulation pain | 0 | 0 | 10 (0.04) | 0 | 2 (0.00) | 61 (0.03) | 74 (0.03) |
Oxygen saturation decreased | 154 (1.45) | 122 (0.88) | 42 (0.16) | 0 | 407 (0.76) | 541 (0.29) | 1388 (0.47) |
Pain | 52 (0.49) | 266 (1.93) | 2047 (7.96) | 3 (1.04) | 1240 (2.32) | 8236 (4.36) | 12000 (4.10) |
Pain in extremity | 44 (0.42) | 327 (2.37) | 2602 (10.11) | 3 (1.04) | 1304 (2.44) | 10656 (5.65) | 15119 (5.17) |
Pain in jaw | 2 (0.02) | 16 (0.12) | 78 (0.30) | 0 | 73 (0.14) | 335 (0.18) | 514 (0.18) |
Pain of skin | 2 (0.02) | 7 (0.05) | 86 (0.33) | 0 | 29 (0.05) | 317 (0.17) | 446 (0.15) |
Painful respiration | 1 (0.01) | 7 (0.05) | 23 (0.09) | 0 | 41 (0.08) | 84 (0.04) | 163 (0.06) |
Palatal oedema | 0 | 14 (0.10) | 2 (0.01) | 0 | 16 (0.03) | 51 (0.03) | 84 (0.03) |
Pallor | 16 (0.15) | 86 (0.62) | 40 (0.16) | 0 | 219 (0.41) | 549 (0.29) | 944 (0.32) |
Palpitations | 20 (0.19) | 405 (2.93) | 1006 (3.91) | 3 (1.04) | 1715 (3.21) | 4572 (2.42) | 7830 (2.68) |
Pancreatitis | 2 (0.02) | 11 (0.08) | 5 (0.02) | 0 | 96 (0.18) | 64 (0.03) | 187 (0.06) |
Pancreatitis acute | 7 (0.07) | 23 (0.17) | 0 | 0 | 194 (0.36) | 47 (0.02) | 277 (0.09) |
Pancytopenia | 10 (0.09) | 18 (0.13) | 0 | 0 | 42 (0.08) | 21 (0.01) | 104 (0.04) |
Panic attack | 2 (0.02) | 25 (0.18) | 73 (0.28) | 0 | 104 (0.19) | 199 (0.11) | 416 (0.14) |
Panic reaction | 0 | 9 (0.07) | 9 (0.03) | 0 | 11 (0.02) | 60 (0.03) | 92 (0.03) |
Papilloedema | 0 | 1 (0.01) | 9 (0.03) | 0 | 17 (0.03) | 27 (0.01) | 61 (0.02) |
Papule | 0 | 1 (0.01) | 6 (0.02) | 0 | 9 (0.02) | 70 (0.04) | 88 (0.03) |
Paraesthesia | 7 (0.07) | 270 (1.96) | 1176 (4.57) | 1 (0.35) | 1855 (3.47) | 4669 (2.47) | 8111 (2.77) |
Paraesthesia oral | 1 (0.01) | 83 (0.60) | 90 (0.35) | 0 | 210 (0.39) | 826 (0.44) | 1225 (0.42) |
Paralysis | 14 (0.13) | 50 (0.36) | 119 (0.46) | 0 | 164 (0.31) | 418 (0.22) | 827 (0.28) |
Paranasal sinus discomfort | 0 | 1 (0.01) | 11 (0.04) | 0 | 2 (0.00) | 38 (0.02) | 52 (0.02) |
Paraparesis | 1 (0.01) | 4 (0.03) | 11 (0.04) | 0 | 25 (0.05) | 20 (0.01) | 64 (0.02) |
Paresis | 2 (0.02) | 13 (0.09) | 30 (0.12) | 0 | 84 (0.16) | 41 (0.02) | 183 (0.06) |
Parkinson's disease | 4 (0.04) | 2 (0.01) | 7 (0.03) | 0 | 7 (0.01) | 38 (0.02) | 61 (0.02) |
Parosmia | 0 | 6 (0.04) | 112 (0.44) | 0 | 23 (0.04) | 167 (0.09) | 308 (0.11) |
Partial seizures | 1 (0.01) | 7 (0.05) | 6 (0.02) | 0 | 28 (0.05) | 48 (0.03) | 93 (0.03) |
Pelvic pain | 0 | 4 (0.03) | 39 (0.15) | 0 | 20 (0.04) | 138 (0.07) | 203 (0.07) |
Pelvic venous thrombosis | 2 (0.02) | 12 (0.09) | 2 (0.01) | 0 | 36 (0.07) | 17 (0.01) | 72 (0.02) |
Pemphigoid | 6 (0.06) | 9 (0.07) | 15 (0.06) | 0 | 29 (0.05) | 80 (0.04) | 142 (0.05) |
Performance status decreased | 0 | 5 (0.04) | 7 (0.03) | 0 | 19 (0.04) | 16 (0.01) | 53 (0.02) |
Periarthritis | 0 | 0 | 127 (0.49) | 0 | 7 (0.01) | 157 (0.08) | 295 (0.10) |
Pericardial effusion | 20 (0.19) | 77 (0.56) | 21 (0.08) | 0 | 361 (0.68) | 358 (0.19) | 881 (0.30) |
Pericarditis | 18 (0.17) | 275 (1.99) | 242 (0.94) | 1 (0.35) | 1722 (3.22) | 4631 (2.45) | 6961 (2.38) |
Periorbital oedema | 0 | 4 (0.03) | 4 (0.02) | 0 | 21 (0.04) | 50 (0.03) | 82 (0.03) |
Periorbital swelling | 0 | 7 (0.05) | 13 (0.05) | 0 | 35 (0.07) | 132 (0.07) | 187 (0.06) |
Peripheral artery thrombosis | 2 (0.02) | 17 (0.12) | 6 (0.02) | 0 | 46 (0.09) | 24 (0.01) | 97 (0.03) |
Peripheral coldness | 5 (0.05) | 26 (0.19) | 94 (0.37) | 0 | 121 (0.23) | 397 (0.21) | 658 (0.22) |
Peripheral ischaemia | 14 (0.13) | 10 (0.07) | 6 (0.02) | 0 | 40 (0.07) | 15 (0.01) | 88 (0.03) |
Peripheral swelling | 18 (0.17) | 147 (1.06) | 526 (2.04) | 2 (0.69) | 415 (0.78) | 2708 (1.43) | 3874 (1.32) |
Peripheral vascular disorder | 7 (0.07) | 5 (0.04) | 5 (0.02) | 0 | 34 (0.06) | 16 (0.01) | 72 (0.02) |
Petechiae | 15 (0.14) | 46 (0.33) | 25 (0.10) | 0 | 184 (0.34) | 196 (0.10) | 487 (0.17) |
Petit mal epilepsy | 1 (0.01) | 7 (0.05) | 1 (0.00) | 0 | 21 (0.04) | 68 (0.04) | 102 (0.03) |
Pharyngeal hypoaesthesia | 0 | 6 (0.04) | 7 (0.03) | 0 | 16 (0.03) | 43 (0.02) | 76 (0.03) |
Pharyngeal oedema | 1 (0.01) | 32 (0.23) | 10 (0.04) | 0 | 48 (0.09) | 82 (0.04) | 177 (0.06) |
Pharyngeal paraesthesia | 0 | 17 (0.12) | 6 (0.02) | 0 | 35 (0.07) | 76 (0.04) | 136 (0.05) |
Pharyngeal swelling | 3 (0.03) | 158 (1.14) | 50 (0.19) | 0 | 152 (0.28) | 466 (0.25) | 852 (0.29) |
Pharyngitis | 0 | 6 (0.04) | 12 (0.05) | 0 | 22 (0.04) | 52 (0.03) | 95 (0.03) |
Phlebitis | 0 | 14 (0.10) | 16 (0.06) | 0 | 45 (0.08) | 129 (0.07) | 207 (0.07) |
Photophobia | 0 | 23 (0.17) | 170 (0.66) | 0 | 119 (0.22) | 460 (0.24) | 780 (0.27) |
Photopsia | 0 | 11 (0.08) | 33 (0.13) | 0 | 39 (0.07) | 144 (0.08) | 231 (0.08) |
Photosensitivity reaction | 0 | 5 (0.04) | 32 (0.12) | 0 | 14 (0.03) | 76 (0.04) | 131 (0.04) |
Physical deconditioning | 7 (0.07) | 3 (0.02) | 8 (0.03) | 0 | 54 (0.10) | 41 (0.02) | 128 (0.04) |
Pityriasis rosea | 0 | 0 | 4 (0.02) | 0 | 5 (0.01) | 72 (0.04) | 81 (0.03) |
Platelet count decreased | 21 (0.20) | 71 (0.51) | 15 (0.06) | 0 | 122 (0.23) | 145 (0.08) | 411 (0.14) |
Platelet count increased | 2 (0.02) | 3 (0.02) | 4 (0.02) | 0 | 14 (0.03) | 24 (0.01) | 51 (0.02) |
Pleural effusion | 27 (0.25) | 63 (0.46) | 8 (0.03) | 1 (0.35) | 217 (0.41) | 65 (0.03) | 432 (0.15) |
Pleurisy | 2 (0.02) | 17 (0.12) | 12 (0.05) | 0 | 112 (0.21) | 54 (0.03) | 206 (0.07) |
Pleuritic pain | 1 (0.01) | 9 (0.07) | 11 (0.04) | 0 | 50 (0.09) | 22 (0.01) | 94 (0.03) |
Pneumonia | 337 (3.18) | 193 (1.40) | 30 (0.12) | 0 | 622 (1.16) | 485 (0.26) | 1812 (0.62) |
Pneumonia aspiration | 98 (0.93) | 16 (0.12) | 1 (0.00) | 0 | 36 (0.07) | 14 (0.01) | 184 (0.06) |
Pneumonia bacterial | 16 (0.15) | 2 (0.01) | 0 | 0 | 21 (0.04) | 9 (0.00) | 56 (0.02) |
Pneumonitis | 22 (0.21) | 26 (0.19) | 7 (0.03) | 0 | 79 (0.15) | 34 (0.02) | 181 (0.06) |
Pneumothorax | 2 (0.02) | 13 (0.09) | 2 (0.01) | 0 | 52 (0.10) | 30 (0.02) | 112 (0.04) |
Pollakiuria | 3 (0.03) | 5 (0.04) | 34 (0.13) | 0 | 24 (0.04) | 122 (0.06) | 200 (0.07) |
Polyarthritis | 0 | 2 (0.01) | 20 (0.08) | 0 | 42 (0.08) | 100 (0.05) | 167 (0.06) |
Polymenorrhoea | 1 (0.01) | 4 (0.03) | 114 (0.44) | 0 | 26 (0.05) | 543 (0.29) | 689 (0.24) |
Polymyalgia rheumatica | 0 | 5 (0.04) | 91 (0.35) | 0 | 76 (0.14) | 323 (0.17) | 504 (0.17) |
Polyneuropathy | 1 (0.01) | 5 (0.04) | 38 (0.15) | 0 | 75 (0.14) | 124 (0.07) | 259 (0.09) |
Poor peripheral circulation | 0 | 8 (0.06) | 9 (0.03) | 0 | 19 (0.04) | 24 (0.01) | 64 (0.02) |
Poor quality sleep | 2 (0.02) | 1 (0.01) | 61 (0.24) | 0 | 22 (0.04) | 228 (0.12) | 316 (0.11) |
Portal vein thrombosis | 14 (0.13) | 23 (0.17) | 2 (0.01) | 0 | 76 (0.14) | 16 (0.01) | 136 (0.05) |
Post herpetic neuralgia | 0 | 0 | 20 (0.08) | 0 | 14 (0.03) | 34 (0.02) | 70 (0.02) |
Post viral fatigue syndrome | 0 | 0 | 56 (0.22) | 0 | 3 (0.01) | 65 (0.03) | 127 (0.04) |
Post-acute COVID-19 syndrome | 0 | 3 (0.02) | 16 (0.06) | 0 | 5 (0.01) | 31 (0.02) | 63 (0.02) |
Postmenopausal haemorrhage | 0 | 6 (0.04) | 24 (0.09) | 0 | 27 (0.05) | 1126 (0.60) | 1183 (0.40) |
Postural orthostatic tachycardia syndrome | 0 | 3 (0.02) | 45 (0.17) | 0 | 26 (0.05) | 33 (0.02) | 112 (0.04) |
Premature baby | 4 (0.04) | 13 (0.09) | 0 | 2 (0.69) | 34 (0.06) | 15 (0.01) | 75 (0.03) |
Premenstrual pain | 0 | 0 | 16 (0.06) | 0 | 1 (0.00) | 109 (0.06) | 126 (0.04) |
Premenstrual syndrome | 0 | 2 (0.01) | 29 (0.11) | 0 | 4 (0.01) | 157 (0.08) | 194 (0.07) |
Presyncope | 7 (0.07) | 91 (0.66) | 144 (0.56) | 0 | 449 (0.84) | 1292 (0.68) | 2022 (0.69) |
Product administered at inappropriate site | 0 | 3 (0.02) | 25 (0.10) | 0 | 2 (0.00) | 23 (0.01) | 56 (0.02) |
Product use issue | 8 (0.08) | 9 (0.07) | 27 (0.10) | 1 (0.35) | 26 (0.05) | 366 (0.19) | 443 (0.15) |
Productive cough | 13 (0.12) | 13 (0.09) | 47 (0.18) | 0 | 79 (0.15) | 204 (0.11) | 372 (0.13) |
Proteinuria | 0 | 5 (0.04) | 5 (0.02) | 0 | 29 (0.05) | 29 (0.02) | 72 (0.02) |
Pruritus | 8 (0.08) | 197 (1.43) | 424 (1.65) | 2 (0.69) | 846 (1.58) | 4560 (2.42) | 6125 (2.09) |
Psoriasis | 1 (0.01) | 2 (0.01) | 40 (0.16) | 0 | 35 (0.07) | 208 (0.11) | 287 (0.10) |
Psoriatic arthropathy | 0 | 0 | 17 (0.07) | 0 | 3 (0.01) | 71 (0.04) | 92 (0.03) |
Psychomotor hyperactivity | 4 (0.04) | 5 (0.04) | 5 (0.02) | 0 | 5 (0.01) | 31 (0.02) | 52 (0.02) |
Psychotic disorder | 0 | 9 (0.07) | 12 (0.05) | 0 | 31 (0.06) | 18 (0.01) | 73 (0.02) |
Pulmonary congestion | 13 (0.12) | 3 (0.02) | 2 (0.01) | 0 | 22 (0.04) | 69 (0.04) | 125 (0.04) |
Pulmonary embolism | 402 (3.80) | 1465 (10.61) | 63 (0.24) | 0 | 2638 (4.93) | 1007 (0.53) | 5654 (1.93) |
Pulmonary fibrosis | 10 (0.09) | 7 (0.05) | 5 (0.02) | 0 | 10 (0.02) | 18 (0.01) | 55 (0.02) |
Pulmonary hypertension | 6 (0.06) | 7 (0.05) | 1 (0.00) | 0 | 20 (0.04) | 11 (0.01) | 53 (0.02) |
Pulmonary infarction | 8 (0.08) | 37 (0.27) | 2 (0.01) | 0 | 70 (0.13) | 24 (0.01) | 149 (0.05) |
Pulmonary oedema | 83 (0.78) | 52 (0.38) | 9 (0.03) | 0 | 80 (0.15) | 45 (0.02) | 313 (0.11) |
Pulmonary pain | 1 (0.01) | 11 (0.08) | 53 (0.21) | 0 | 46 (0.09) | 111 (0.06) | 225 (0.08) |
Pulmonary thrombosis | 16 (0.15) | 80 (0.58) | 7 (0.03) | 0 | 98 (0.18) | 51 (0.03) | 270 (0.09) |
Pulse abnormal | 3 (0.03) | 14 (0.10) | 7 (0.03) | 0 | 29 (0.05) | 48 (0.03) | 105 (0.04) |
Purpura | 7 (0.07) | 11 (0.08) | 9 (0.03) | 0 | 74 (0.14) | 99 (0.05) | 208 (0.07) |
Pyelonephritis | 5 (0.05) | 6 (0.04) | 3 (0.01) | 0 | 45 (0.08) | 43 (0.02) | 106 (0.04) |
Pyrexia | 503 (4.75) | 791 (5.73) | 4264 (16.58) | 15 (5.21) | 4438 (8.30) | 13788 (7.31) | 24210 (8.27) |
Quadriparesis | 2 (0.02) | 7 (0.05) | 8 (0.03) | 0 | 29 (0.05) | 2 (0.00) | 51 (0.02) |
Radiculopathy | 1 (0.01) | 0 | 13 (0.05) | 0 | 28 (0.05) | 16 (0.01) | 59 (0.02) |
Rales | 11 (0.10) | 1 (0.01) | 5 (0.02) | 0 | 10 (0.02) | 20 (0.01) | 51 (0.02) |
Rash | 19 (0.18) | 237 (1.72) | 446 (1.73) | 2 (0.69) | 1276 (2.39) | 4345 (2.30) | 6414 (2.19) |
Rash erythematous | 2 (0.02) | 31 (0.22) | 68 (0.26) | 0 | 122 (0.23) | 831 (0.44) | 1063 (0.36) |
Rash macular | 3 (0.03) | 23 (0.17) | 55 (0.21) | 0 | 51 (0.10) | 390 (0.21) | 530 (0.18) |
Rash maculo-papular | 0 | 8 (0.06) | 2 (0.01) | 0 | 77 (0.14) | 103 (0.05) | 192 (0.07) |
Rash morbilliform | 0 | 0 | 6 (0.02) | 0 | 7 (0.01) | 34 (0.02) | 51 (0.02) |
Rash papular | 0 | 4 (0.03) | 17 (0.07) | 0 | 35 (0.07) | 207 (0.11) | 265 (0.09) |
Rash pruritic | 4 (0.04) | 22 (0.16) | 68 (0.26) | 0 | 104 (0.19) | 859 (0.46) | 1074 (0.37) |
Rash vesicular | 0 | 4 (0.03) | 14 (0.05) | 0 | 22 (0.04) | 95 (0.05) | 138 (0.05) |
Raynaud's phenomenon | 0 | 3 (0.02) | 10 (0.04) | 0 | 11 (0.02) | 79 (0.04) | 105 (0.04) |
Rectal haemorrhage | 10 (0.09) | 7 (0.05) | 13 (0.05) | 1 (0.35) | 54 (0.10) | 185 (0.10) | 280 (0.10) |
Red blood cell sedimentation rate increased | 2 (0.02) | 3 (0.02) | 13 (0.05) | 0 | 25 (0.05) | 28 (0.01) | 76 (0.03) |
Renal disorder | 7 (0.07) | 16 (0.12) | 7 (0.03) | 0 | 32 (0.06) | 24 (0.01) | 93 (0.03) |
Renal failure | 93 (0.88) | 63 (0.46) | 5 (0.02) | 0 | 98 (0.18) | 58 (0.03) | 364 (0.12) |
Renal impairment | 16 (0.15) | 22 (0.16) | 7 (0.03) | 0 | 55 (0.10) | 85 (0.05) | 214 (0.07) |
Renal infarct | 1 (0.01) | 10 (0.07) | 6 (0.02) | 0 | 26 (0.05) | 5 (0.00) | 53 (0.02) |
Renal pain | 1 (0.01) | 11 (0.08) | 72 (0.28) | 1 (0.35) | 46 (0.09) | 284 (0.15) | 419 (0.14) |
Respiration abnormal | 7 (0.07) | 16 (0.12) | 12 (0.05) | 0 | 61 (0.11) | 106 (0.06) | 208 (0.07) |
Respiratory arrest | 141 (1.33) | 47 (0.34) | 4 (0.02) | 0 | 22 (0.04) | 37 (0.02) | 287 (0.10) |
Respiratory disorder | 31 (0.29) | 43 (0.31) | 77 (0.30) | 0 | 88 (0.16) | 120 (0.06) | 379 (0.13) |
Respiratory distress | 67 (0.63) | 62 (0.45) | 19 (0.07) | 0 | 312 (0.58) | 1050 (0.56) | 1596 (0.55) |
Respiratory failure | 200 (1.89) | 78 (0.56) | 5 (0.02) | 0 | 139 (0.26) | 42 (0.02) | 510 (0.17) |
Respiratory rate increased | 7 (0.07) | 17 (0.12) | 11 (0.04) | 0 | 51 (0.10) | 74 (0.04) | 168 (0.06) |
Respiratory symptom | 0 | 1 (0.01) | 5 (0.02) | 0 | 16 (0.03) | 34 (0.02) | 56 (0.02) |
Respiratory tract infection | 10 (0.09) | 3 (0.02) | 1 (0.00) | 0 | 14 (0.03) | 50 (0.03) | 90 (0.03) |
Respiratory tract oedema | 0 | 16 (0.12) | 2 (0.01) | 0 | 10 (0.02) | 27 (0.01) | 60 (0.02) |
Restless legs syndrome | 1 (0.01) | 1 (0.01) | 33 (0.13) | 0 | 17 (0.03) | 93 (0.05) | 146 (0.05) |
Restlessness | 15 (0.14) | 14 (0.10) | 43 (0.17) | 0 | 103 (0.19) | 188 (0.10) | 376 (0.13) |
Resuscitation | 26 (0.25) | 20 (0.14) | 1 (0.00) | 0 | 15 (0.03) | 3 (0.00) | 69 (0.02) |
Retching | 3 (0.03) | 13 (0.09) | 33 (0.13) | 0 | 52 (0.10) | 122 (0.06) | 231 (0.08) |
Retinal artery occlusion | 0 | 2 (0.01) | 51 (0.20) | 0 | 35 (0.07) | 53 (0.03) | 142 (0.05) |
Retinal detachment | 0 | 1 (0.01) | 17 (0.07) | 0 | 56 (0.10) | 51 (0.03) | 129 (0.04) |
Retinal haemorrhage | 0 | 1 (0.01) | 15 (0.06) | 0 | 13 (0.02) | 58 (0.03) | 88 (0.03) |
Retinal tear | 0 | 0 | 9 (0.03) | 0 | 8 (0.01) | 30 (0.02) | 53 (0.02) |
Retinal vascular thrombosis | 0 | 2 (0.01) | 23 (0.09) | 0 | 11 (0.02) | 21 (0.01) | 58 (0.02) |
Retinal vein occlusion | 0 | 1 (0.01) | 80 (0.31) | 0 | 30 (0.06) | 187 (0.10) | 302 (0.10) |
Retinal vein thrombosis | 0 | 3 (0.02) | 28 (0.11) | 0 | 5 (0.01) | 48 (0.03) | 87 (0.03) |
Rhabdomyolysis | 8 (0.08) | 20 (0.14) | 6 (0.02) | 0 | 101 (0.19) | 50 (0.03) | 191 (0.07) |
Rheumatic disorder | 0 | 1 (0.01) | 16 (0.06) | 0 | 22 (0.04) | 32 (0.02) | 75 (0.03) |
Rheumatoid arthritis | 2 (0.02) | 9 (0.07) | 134 (0.52) | 0 | 61 (0.11) | 541 (0.29) | 760 (0.26) |
Rhinitis | 0 | 6 (0.04) | 35 (0.14) | 0 | 14 (0.03) | 80 (0.04) | 135 (0.05) |
Rhinorrhoea | 3 (0.03) | 24 (0.17) | 111 (0.43) | 0 | 106 (0.20) | 788 (0.42) | 1042 (0.36) |
Road traffic accident | 4 (0.04) | 2 (0.01) | 2 (0.01) | 0 | 22 (0.04) | 32 (0.02) | 70 (0.02) |
Rotator cuff syndrome | 0 | 1 (0.01) | 29 (0.11) | 0 | 4 (0.01) | 61 (0.03) | 96 (0.03) |
SARS-CoV-2 test negative | 6 (0.06) | 12 (0.09) | 36 (0.14) | 0 | 25 (0.05) | 15 (0.01) | 94 (0.03) |
SARS-CoV-2 test positive | 77 (0.73) | 10 (0.07) | 10 (0.04) | 0 | 148 (0.28) | 523 (0.28) | 798 (0.27) |
Salivary hypersecretion | 2 (0.02) | 5 (0.04) | 9 (0.03) | 0 | 15 (0.03) | 44 (0.02) | 78 (0.03) |
Sarcoidosis | 0 | 1 (0.01) | 13 (0.05) | 0 | 29 (0.05) | 60 (0.03) | 107 (0.04) |
Scar | 0 | 1 (0.01) | 15 (0.06) | 0 | 5 (0.01) | 34 (0.02) | 56 (0.02) |
Sciatica | 0 | 4 (0.03) | 82 (0.32) | 0 | 27 (0.05) | 121 (0.06) | 242 (0.08) |
Seasonal allergy | 0 | 2 (0.01) | 10 (0.04) | 0 | 2 (0.00) | 80 (0.04) | 94 (0.03) |
Secretion discharge | 5 (0.05) | 5 (0.04) | 10 (0.04) | 0 | 9 (0.02) | 28 (0.01) | 59 (0.02) |
Seizure | 66 (0.62) | 244 (1.77) | 128 (0.50) | 0 | 891 (1.67) | 1763 (0.93) | 3199 (1.09) |
Sensation of foreign body | 0 | 46 (0.33) | 17 (0.07) | 0 | 119 (0.22) | 207 (0.11) | 392 (0.13) |
Sense of oppression | 2 (0.02) | 5 (0.04) | 18 (0.07) | 0 | 19 (0.04) | 25 (0.01) | 69 (0.02) |
Sensitive skin | 0 | 1 (0.01) | 35 (0.14) | 0 | 110 (0.21) | 353 (0.19) | 503 (0.17) |
Sensory disturbance | 1 (0.01) | 13 (0.09) | 75 (0.29) | 0 | 199 (0.37) | 190 (0.10) | 500 (0.17) |
Sensory loss | 1 (0.01) | 17 (0.12) | 73 (0.28) | 0 | 74 (0.14) | 113 (0.06) | 289 (0.10) |
Sepsis | 128 (1.21) | 61 (0.44) | 11 (0.04) | 0 | 120 (0.22) | 42 (0.02) | 395 (0.13) |
Septic shock | 77 (0.73) | 24 (0.17) | 0 | 0 | 23 (0.04) | 5 (0.00) | 142 (0.05) |
Shock | 39 (0.37) | 50 (0.36) | 9 (0.03) | 0 | 44 (0.08) | 143 (0.08) | 333 (0.11) |
Shoulder injury related to vaccine administration | 0 | 0 | 45 (0.17) | 0 | 0 | 61 (0.03) | 107 (0.04) |
Sinus bradycardia | 0 | 4 (0.03) | 4 (0.02) | 0 | 23 (0.04) | 16 (0.01) | 52 (0.02) |
Sinus congestion | 0 | 3 (0.02) | 12 (0.05) | 0 | 2 (0.00) | 56 (0.03) | 74 (0.03) |
Sinus headache | 0 | 1 (0.01) | 29 (0.11) | 0 | 6 (0.01) | 203 (0.11) | 239 (0.08) |
Sinus pain | 0 | 4 (0.03) | 31 (0.12) | 0 | 11 (0.02) | 168 (0.09) | 216 (0.07) |
Sinus tachycardia | 1 (0.01) | 19 (0.14) | 23 (0.09) | 0 | 114 (0.21) | 112 (0.06) | 274 (0.09) |
Sinusitis | 2 (0.02) | 4 (0.03) | 49 (0.19) | 0 | 31 (0.06) | 179 (0.09) | 271 (0.09) |
Sjogren's syndrome | 0 | 1 (0.01) | 6 (0.02) | 0 | 6 (0.01) | 50 (0.03) | 69 (0.02) |
Skin burning sensation | 1 (0.01) | 17 (0.12) | 61 (0.24) | 0 | 42 (0.08) | 232 (0.12) | 359 (0.12) |
Skin discolouration | 3 (0.03) | 14 (0.10) | 33 (0.13) | 0 | 65 (0.12) | 184 (0.10) | 312 (0.11) |
Skin disorder | 3 (0.03) | 21 (0.15) | 241 (0.94) | 1 (0.35) | 39 (0.07) | 122 (0.06) | 437 (0.15) |
Skin exfoliation | 0 | 3 (0.02) | 30 (0.12) | 1 (0.35) | 23 (0.04) | 135 (0.07) | 199 (0.07) |
Skin haemorrhage | 2 (0.02) | 6 (0.04) | 5 (0.02) | 0 | 15 (0.03) | 23 (0.01) | 55 (0.02) |
Skin irritation | 0 | 5 (0.04) | 16 (0.06) | 0 | 3 (0.01) | 93 (0.05) | 117 (0.04) |
Skin laceration | 0 | 1 (0.01) | 3 (0.01) | 0 | 10 (0.02) | 32 (0.02) | 51 (0.02) |
Skin lesion | 3 (0.03) | 3 (0.02) | 11 (0.04) | 0 | 13 (0.02) | 63 (0.03) | 96 (0.03) |
Skin mass | 0 | 0 | 3 (0.01) | 0 | 7 (0.01) | 46 (0.02) | 57 (0.02) |
Skin reaction | 1 (0.01) | 13 (0.09) | 12 (0.05) | 0 | 21 (0.04) | 127 (0.07) | 174 (0.06) |
Skin swelling | 0 | 1 (0.01) | 8 (0.03) | 0 | 8 (0.01) | 65 (0.03) | 83 (0.03) |
Skin ulcer | 3 (0.03) | 3 (0.02) | 9 (0.03) | 0 | 17 (0.03) | 33 (0.02) | 67 (0.02) |
Skin warm | 1 (0.01) | 3 (0.02) | 15 (0.06) | 0 | 14 (0.03) | 208 (0.11) | 244 (0.08) |
Sleep disorder | 1 (0.01) | 19 (0.14) | 223 (0.87) | 1 (0.35) | 79 (0.15) | 542 (0.29) | 875 (0.30) |
Slow speech | 2 (0.02) | 5 (0.04) | 12 (0.05) | 0 | 12 (0.02) | 19 (0.01) | 51 (0.02) |
Sneezing | 2 (0.02) | 7 (0.05) | 47 (0.18) | 0 | 16 (0.03) | 280 (0.15) | 353 (0.12) |
Somnolence | 50 (0.47) | 104 (0.75) | 304 (1.18) | 1 (0.35) | 283 (0.53) | 1294 (0.69) | 2079 (0.71) |
Speech disorder | 14 (0.13) | 81 (0.59) | 98 (0.38) | 0 | 250 (0.47) | 229 (0.12) | 717 (0.25) |
Spinal pain | 2 (0.02) | 6 (0.04) | 50 (0.19) | 0 | 37 (0.07) | 143 (0.08) | 244 (0.08) |
Splenomegaly | 2 (0.02) | 6 (0.04) | 2 (0.01) | 0 | 33 (0.06) | 16 (0.01) | 66 (0.02) |
Status epilepticus | 10 (0.09) | 34 (0.25) | 7 (0.03) | 0 | 47 (0.09) | 70 (0.04) | 171 (0.06) |
Stevens-Johnson syndrome | 4 (0.04) | 1 (0.01) | 0 | 0 | 18 (0.03) | 33 (0.02) | 60 (0.02) |
Stomatitis | 0 | 8 (0.06) | 9 (0.03) | 0 | 16 (0.03) | 82 (0.04) | 120 (0.04) |
Stress | 0 | 11 (0.08) | 48 (0.19) | 0 | 24 (0.04) | 124 (0.07) | 214 (0.07) |
Stress cardiomyopathy | 4 (0.04) | 17 (0.12) | 1 (0.00) | 0 | 45 (0.08) | 5 (0.00) | 75 (0.03) |
Stridor | 2 (0.02) | 40 (0.29) | 1 (0.00) | 0 | 58 (0.11) | 63 (0.03) | 168 (0.06) |
Subarachnoid haemorrhage | 90 (0.85) | 78 (0.56) | 6 (0.02) | 0 | 95 (0.18) | 12 (0.01) | 289 (0.10) |
Subclavian vein thrombosis | 3 (0.03) | 13 (0.09) | 2 (0.01) | 0 | 19 (0.04) | 29 (0.02) | 67 (0.02) |
Subdural haematoma | 9 (0.08) | 29 (0.21) | 1 (0.00) | 0 | 48 (0.09) | 7 (0.00) | 99 (0.03) |
Sudden cardiac death | 78 (0.74) | 0 | 0 | 0 | 0 | 0 | 78 (0.03) |
Sudden death | 650 (6.14) | 0 | 0 | 0 | 0 | 0 | 650 (0.22) |
Sudden hearing loss | 0 | 1 (0.01) | 82 (0.32) | 0 | 56 (0.10) | 318 (0.17) | 462 (0.16) |
Suffocation feeling | 0 | 20 (0.14) | 10 (0.04) | 0 | 17 (0.03) | 27 (0.01) | 75 (0.03) |
Suicidal ideation | 2 (0.02) | 32 (0.23) | 26 (0.10) | 0 | 11 (0.02) | 175 (0.09) | 263 (0.09) |
Superficial vein thrombosis | 0 | 29 (0.21) | 8 (0.03) | 0 | 71 (0.13) | 359 (0.19) | 472 (0.16) |
Suppressed lactation | 0 | 1 (0.01) | 8 (0.03) | 0 | 3 (0.01) | 44 (0.02) | 56 (0.02) |
Supraventricular extrasystoles | 0 | 7 (0.05) | 9 (0.03) | 0 | 17 (0.03) | 57 (0.03) | 94 (0.03) |
Supraventricular tachycardia | 1 (0.01) | 28 (0.20) | 11 (0.04) | 1 (0.35) | 85 (0.16) | 82 (0.04) | 215 (0.07) |
Suspected COVID-19 | 29 (0.27) | 15 (0.11) | 75 (0.29) | 0 | 84 (0.16) | 1459 (0.77) | 1725 (0.59) |
Sweating fever | 0 | 1 (0.01) | 11 (0.04) | 0 | 2 (0.00) | 114 (0.06) | 128 (0.04) |
Swelling | 7 (0.07) | 104 (0.75) | 275 (1.07) | 1 (0.35) | 287 (0.54) | 2264 (1.20) | 2971 (1.02) |
Swelling face | 5 (0.05) | 123 (0.89) | 124 (0.48) | 0 | 262 (0.49) | 1054 (0.56) | 1600 (0.55) |
Swelling of eyelid | 0 | 7 (0.05) | 14 (0.05) | 2 (0.69) | 25 (0.05) | 164 (0.09) | 213 (0.07) |
Swollen tongue | 3 (0.03) | 168 (1.22) | 55 (0.21) | 0 | 212 (0.40) | 553 (0.29) | 1010 (0.35) |
Syncope | 88 (0.83) | 391 (2.83) | 305 (1.19) | 3 (1.04) | 1241 (2.32) | 6444 (3.41) | 8688 (2.97) |
Systemic inflammatory response syndrome | 8 (0.08) | 17 (0.12) | 0 | 0 | 27 (0.05) | 18 (0.01) | 75 (0.03) |
Systemic lupus erythematosus | 1 (0.01) | 8 (0.06) | 11 (0.04) | 0 | 43 (0.08) | 116 (0.06) | 186 (0.06) |
Tachyarrhythmia | 2 (0.02) | 14 (0.10) | 5 (0.02) | 0 | 11 (0.02) | 25 (0.01) | 59 (0.02) |
Tachycardia | 61 (0.58) | 444 (3.22) | 466 (1.81) | 5 (1.74) | 1729 (3.23) | 2925 (1.55) | 5749 (1.96) |
Tachypnoea | 33 (0.31) | 37 (0.27) | 5 (0.02) | 0 | 134 (0.25) | 129 (0.07) | 384 (0.13) |
Taste disorder | 2 (0.02) | 11 (0.08) | 112 (0.44) | 0 | 50 (0.09) | 205 (0.11) | 385 (0.13) |
Tearfulness | 0 | 3 (0.02) | 2 (0.01) | 0 | 2 (0.00) | 50 (0.03) | 57 (0.02) |
Temperature intolerance | 0 | 2 (0.01) | 10 (0.04) | 0 | 8 (0.01) | 41 (0.02) | 62 (0.02) |
Temperature regulation disorder | 0 | 1 (0.01) | 11 (0.04) | 0 | 4 (0.01) | 42 (0.02) | 60 (0.02) |
Tenderness | 2 (0.02) | 3 (0.02) | 44 (0.17) | 0 | 30 (0.06) | 337 (0.18) | 421 (0.14) |
Tendon pain | 0 | 2 (0.01) | 25 (0.10) | 0 | 7 (0.01) | 43 (0.02) | 79 (0.03) |
Tendonitis | 0 | 2 (0.01) | 39 (0.15) | 0 | 10 (0.02) | 82 (0.04) | 136 (0.05) |
Tension | 0 | 0 | 16 (0.06) | 0 | 7 (0.01) | 49 (0.03) | 73 (0.02) |
Tension headache | 0 | 5 (0.04) | 78 (0.30) | 0 | 40 (0.07) | 347 (0.18) | 473 (0.16) |
Testicular pain | 1 (0.01) | 1 (0.01) | 13 (0.05) | 0 | 10 (0.02) | 64 (0.03) | 92 (0.03) |
Thalamic infarction | 1 (0.01) | 12 (0.09) | 5 (0.02) | 0 | 36 (0.07) | 6 (0.00) | 63 (0.02) |
Thinking abnormal | 0 | 3 (0.02) | 18 (0.07) | 0 | 9 (0.02) | 35 (0.02) | 69 (0.02) |
Thirst | 1 (0.01) | 14 (0.10) | 60 (0.23) | 0 | 38 (0.07) | 264 (0.14) | 382 (0.13) |
Throat irritation | 2 (0.02) | 52 (0.38) | 38 (0.15) | 0 | 135 (0.25) | 474 (0.25) | 712 (0.24) |
Throat tightness | 1 (0.01) | 168 (1.22) | 44 (0.17) | 1 (0.35) | 299 (0.56) | 780 (0.41) | 1331 (0.45) |
Thrombocytopenia | 84 (0.79) | 211 (1.53) | 23 (0.09) | 0 | 467 (0.87) | 561 (0.30) | 1412 (0.48) |
Thrombocytopenic purpura | 4 (0.04) | 13 (0.09) | 1 (0.00) | 0 | 47 (0.09) | 13 (0.01) | 83 (0.03) |
Thrombophlebitis | 3 (0.03) | 28 (0.20) | 18 (0.07) | 0 | 79 (0.15) | 274 (0.15) | 409 (0.14) |
Thrombosis | 130 (1.23) | 453 (3.28) | 135 (0.52) | 1 (0.35) | 672 (1.26) | 1778 (0.94) | 3317 (1.13) |
Thrombosis with thrombocytopenia syndrome | 13 (0.12) | 5 (0.04) | 1 (0.00) | 0 | 18 (0.03) | 8 (0.00) | 51 (0.02) |
Thrombotic thrombocytopenic purpura | 11 (0.10) | 31 (0.22) | 0 | 0 | 22 (0.04) | 9 (0.00) | 74 (0.03) |
Thyroiditis | 0 | 1 (0.01) | 13 (0.05) | 0 | 12 (0.02) | 55 (0.03) | 83 (0.03) |
Thyroiditis subacute | 0 | 0 | 7 (0.03) | 0 | 20 (0.04) | 65 (0.03) | 92 (0.03) |
Tinnitus | 2 (0.02) | 61 (0.44) | 914 (3.55) | 4 (1.39) | 269 (0.50) | 1855 (0.98) | 3143 (1.07) |
Tongue discomfort | 0 | 7 (0.05) | 14 (0.05) | 0 | 9 (0.02) | 50 (0.03) | 81 (0.03) |
Tongue disorder | 0 | 3 (0.02) | 5 (0.02) | 0 | 16 (0.03) | 66 (0.03) | 94 (0.03) |
Tongue oedema | 1 (0.01) | 35 (0.25) | 8 (0.03) | 0 | 40 (0.07) | 120 (0.06) | 205 (0.07) |
Tongue pruritus | 0 | 6 (0.04) | 4 (0.02) | 0 | 18 (0.03) | 38 (0.02) | 67 (0.02) |
Tonic clonic movements | 0 | 7 (0.05) | 2 (0.01) | 0 | 15 (0.03) | 39 (0.02) | 65 (0.02) |
Tonic convulsion | 1 (0.01) | 11 (0.08) | 0 | 0 | 26 (0.05) | 40 (0.02) | 80 (0.03) |
Tonsillar hypertrophy | 0 | 5 (0.04) | 11 (0.04) | 0 | 6 (0.01) | 68 (0.04) | 91 (0.03) |
Tonsillitis | 0 | 6 (0.04) | 14 (0.05) | 0 | 25 (0.05) | 104 (0.06) | 151 (0.05) |
Toothache | 0 | 11 (0.08) | 34 (0.13) | 0 | 23 (0.04) | 174 (0.09) | 244 (0.08) |
Toxic skin eruption | 1 (0.01) | 0 | 1 (0.00) | 0 | 11 (0.02) | 81 (0.04) | 95 (0.03) |
Transaminases increased | 2 (0.02) | 4 (0.03) | 4 (0.02) | 0 | 19 (0.04) | 26 (0.01) | 58 (0.02) |
Transient ischaemic attack | 10 (0.09) | 119 (0.86) | 40 (0.16) | 1 (0.35) | 551 (1.03) | 353 (0.19) | 1110 (0.38) |
Tremor | 19 (0.18) | 160 (1.16) | 512 (1.99) | 0 | 668 (1.25) | 1964 (1.04) | 3389 (1.16) |
Trigeminal neuralgia | 0 | 3 (0.02) | 38 (0.15) | 0 | 35 (0.07) | 144 (0.08) | 220 (0.08) |
Trismus | 1 (0.01) | 4 (0.03) | 10 (0.04) | 0 | 14 (0.03) | 50 (0.03) | 82 (0.03) |
Troponin I increased | 0 | 7 (0.05) | 0 | 0 | 42 (0.08) | 10 (0.01) | 66 (0.02) |
Troponin T increased | 2 (0.02) | 7 (0.05) | 1 (0.00) | 0 | 53 (0.10) | 4 (0.00) | 77 (0.03) |
Troponin increased | 5 (0.05) | 40 (0.29) | 8 (0.03) | 0 | 258 (0.48) | 55 (0.03) | 395 (0.13) |
Tunnel vision | 0 | 0 | 4 (0.02) | 0 | 11 (0.02) | 83 (0.04) | 101 (0.03) |
Type 1 diabetes mellitus | 1 (0.01) | 21 (0.15) | 20 (0.08) | 0 | 40 (0.07) | 45 (0.02) | 130 (0.04) |
Type I hypersensitivity | 0 | 5 (0.04) | 0 | 0 | 10 (0.02) | 118 (0.06) | 137 (0.05) |
Unresponsive to stimuli | 50 (0.47) | 35 (0.25) | 7 (0.03) | 0 | 52 (0.10) | 132 (0.07) | 319 (0.11) |
Urinary incontinence | 6 (0.06) | 20 (0.14) | 28 (0.11) | 0 | 58 (0.11) | 98 (0.05) | 229 (0.08) |
Urinary retention | 6 (0.06) | 12 (0.09) | 24 (0.09) | 0 | 63 (0.12) | 108 (0.06) | 229 (0.08) |
Urinary tract infection | 30 (0.28) | 34 (0.25) | 48 (0.19) | 0 | 144 (0.27) | 257 (0.14) | 550 (0.19) |
Urosepsis | 22 (0.21) | 9 (0.07) | 0 | 0 | 16 (0.03) | 3 (0.00) | 53 (0.02) |
Urticaria | 5 (0.05) | 201 (1.46) | 212 (0.82) | 2 (0.69) | 708 (1.32) | 2910 (1.54) | 4094 (1.40) |
Urticaria chronic | 0 | 10 (0.07) | 14 (0.05) | 0 | 5 (0.01) | 60 (0.03) | 90 (0.03) |
Uterine haemorrhage | 0 | 8 (0.06) | 4 (0.02) | 0 | 16 (0.03) | 88 (0.05) | 117 (0.04) |
Uveitis | 0 | 1 (0.01) | 27 (0.10) | 0 | 21 (0.04) | 141 (0.07) | 195 (0.07) |
VIth nerve paralysis | 0 | 1 (0.01) | 17 (0.07) | 0 | 27 (0.05) | 37 (0.02) | 82 (0.03) |
Vaccination complication | 11 (0.10) | 5 (0.04) | 10 (0.04) | 0 | 38 (0.07) | 90 (0.05) | 159 (0.05) |
Vaccination failure | 702 (6.63) | 161 (1.17) | 14 (0.05) | 0 | 1642 (3.07) | 20452 (10.84) | 23167 (7.92) |
Vaccination site bruising | 0 | 0 | 21 (0.08) | 1 (0.35) | 8 (0.01) | 181 (0.10) | 212 (0.07) |
Vaccination site cellulitis | 0 | 1 (0.01) | 4 (0.02) | 0 | 5 (0.01) | 80 (0.04) | 90 (0.03) |
Vaccination site discomfort | 0 | 1 (0.01) | 11 (0.04) | 0 | 9 (0.02) | 84 (0.04) | 106 (0.04) |
Vaccination site erythema | 4 (0.04) | 15 (0.11) | 126 (0.49) | 0 | 67 (0.13) | 973 (0.52) | 1193 (0.41) |
Vaccination site haematoma | 0 | 1 (0.01) | 11 (0.04) | 0 | 8 (0.01) | 36 (0.02) | 56 (0.02) |
Vaccination site haemorrhage | 0 | 1 (0.01) | 8 (0.03) | 0 | 9 (0.02) | 78 (0.04) | 99 (0.03) |
Vaccination site hypoaesthesia | 0 | 4 (0.03) | 14 (0.05) | 0 | 12 (0.02) | 70 (0.04) | 101 (0.03) |
Vaccination site induration | 0 | 0 | 18 (0.07) | 0 | 12 (0.02) | 107 (0.06) | 138 (0.05) |
Vaccination site inflammation | 1 (0.01) | 0 | 18 (0.07) | 0 | 4 (0.01) | 160 (0.08) | 183 (0.06) |
Vaccination site joint movement impairment | 0 | 0 | 19 (0.07) | 0 | 2 (0.00) | 42 (0.02) | 63 (0.02) |
Vaccination site joint pain | 0 | 1 (0.01) | 18 (0.07) | 0 | 4 (0.01) | 33 (0.02) | 56 (0.02) |
Vaccination site lymphadenopathy | 0 | 0 | 5 (0.02) | 1 (0.35) | 4 (0.01) | 94 (0.05) | 104 (0.04) |
Vaccination site mass | 0 | 5 (0.04) | 45 (0.17) | 0 | 12 (0.02) | 457 (0.24) | 523 (0.18) |
Vaccination site movement impairment | 0 | 6 (0.04) | 124 (0.48) | 0 | 23 (0.04) | 172 (0.09) | 328 (0.11) |
Vaccination site oedema | 0 | 2 (0.01) | 55 (0.21) | 0 | 23 (0.04) | 118 (0.06) | 200 (0.07) |
Vaccination site pain | 21 (0.20) | 118 (0.85) | 1050 (4.08) | 1 (0.35) | 474 (0.89) | 4842 (2.57) | 6555 (2.24) |
Vaccination site paraesthesia | 0 | 4 (0.03) | 15 (0.06) | 0 | 5 (0.01) | 69 (0.04) | 93 (0.03) |
Vaccination site pruritus | 0 | 13 (0.09) | 72 (0.28) | 0 | 38 (0.07) | 423 (0.22) | 550 (0.19) |
Vaccination site rash | 1 (0.01) | 7 (0.05) | 17 (0.07) | 0 | 22 (0.04) | 258 (0.14) | 306 (0.10) |
Vaccination site reaction | 2 (0.02) | 4 (0.03) | 31 (0.12) | 0 | 46 (0.09) | 209 (0.11) | 292 (0.10) |
Vaccination site swelling | 2 (0.02) | 13 (0.09) | 157 (0.61) | 1 (0.35) | 82 (0.15) | 1078 (0.57) | 1342 (0.46) |
Vaccination site urticaria | 0 | 5 (0.04) | 3 (0.01) | 0 | 16 (0.03) | 63 (0.03) | 90 (0.03) |
Vaccination site warmth | 0 | 1 (0.01) | 51 (0.20) | 0 | 23 (0.04) | 495 (0.26) | 572 (0.20) |
Vaginal discharge | 0 | 0 | 6 (0.02) | 1 (0.35) | 4 (0.01) | 53 (0.03) | 64 (0.02) |
Vaginal haemorrhage | 0 | 28 (0.20) | 72 (0.28) | 5 (1.74) | 102 (0.19) | 885 (0.47) | 1100 (0.38) |
Varicose vein | 0 | 6 (0.04) | 13 (0.05) | 0 | 6 (0.01) | 63 (0.03) | 89 (0.03) |
Vascular pain | 1 (0.01) | 4 (0.03) | 10 (0.04) | 0 | 13 (0.02) | 48 (0.03) | 78 (0.03) |
Vasculitis | 10 (0.09) | 25 (0.18) | 19 (0.07) | 0 | 115 (0.22) | 108 (0.06) | 286 (0.10) |
Vasodilatation | 1 (0.01) | 2 (0.01) | 20 (0.08) | 0 | 9 (0.02) | 45 (0.02) | 79 (0.03) |
Venous thrombosis | 1 (0.01) | 45 (0.33) | 15 (0.06) | 0 | 82 (0.15) | 140 (0.07) | 287 (0.10) |
Venous thrombosis limb | 1 (0.01) | 45 (0.33) | 11 (0.04) | 0 | 135 (0.25) | 266 (0.14) | 467 (0.16) |
Ventricular extrasystoles | 1 (0.01) | 16 (0.12) | 23 (0.09) | 0 | 69 (0.13) | 153 (0.08) | 269 (0.09) |
Ventricular fibrillation | 71 (0.67) | 61 (0.44) | 3 (0.01) | 0 | 29 (0.05) | 8 (0.00) | 190 (0.06) |
Ventricular tachycardia | 15 (0.14) | 46 (0.33) | 2 (0.01) | 0 | 53 (0.10) | 24 (0.01) | 157 (0.05) |
Vertigo | 9 (0.08) | 89 (0.64) | 610 (2.37) | 2 (0.69) | 559 (1.05) | 1803 (0.96) | 3124 (1.07) |
Vertigo positional | 0 | 2 (0.01) | 33 (0.13) | 0 | 34 (0.06) | 96 (0.05) | 167 (0.06) |
Vestibular disorder | 0 | 0 | 15 (0.06) | 0 | 14 (0.03) | 25 (0.01) | 56 (0.02) |
Vestibular neuronitis | 0 | 3 (0.02) | 32 (0.12) | 1 (0.35) | 124 (0.23) | 139 (0.07) | 302 (0.10) |
Viral infection | 1 (0.01) | 6 (0.04) | 15 (0.06) | 0 | 44 (0.08) | 62 (0.03) | 132 (0.05) |
Vision blurred | 3 (0.03) | 93 (0.67) | 422 (1.64) | 3 (1.04) | 393 (0.73) | 1278 (0.68) | 2224 (0.76) |
Visual acuity reduced | 1 (0.01) | 5 (0.04) | 37 (0.14) | 0 | 34 (0.06) | 93 (0.05) | 175 (0.06) |
Visual field defect | 0 | 6 (0.04) | 39 (0.15) | 0 | 61 (0.11) | 93 (0.05) | 212 (0.07) |
Visual impairment | 11 (0.10) | 66 (0.48) | 353 (1.37) | 3 (1.04) | 465 (0.87) | 756 (0.40) | 1705 (0.58) |
Vitreous detachment | 0 | 1 (0.01) | 23 (0.09) | 0 | 12 (0.02) | 100 (0.05) | 139 (0.05) |
Vitreous floaters | 0 | 0 | 37 (0.14) | 0 | 12 (0.02) | 101 (0.05) | 153 (0.05) |
Vomiting | 241 (2.28) | 375 (2.72) | 950 (3.69) | 1 (0.35) | 2000 (3.74) | 4605 (2.44) | 8392 (2.87) |
Vomiting projectile | 0 | 2 (0.01) | 11 (0.04) | 0 | 5 (0.01) | 67 (0.04) | 85 (0.03) |
Walking disability | 2 (0.02) | 5 (0.04) | 18 (0.07) | 0 | 12 (0.02) | 16 (0.01) | 57 (0.02) |
Weight bearing difficulty | 0 | 1 (0.01) | 11 (0.04) | 0 | 30 (0.06) | 23 (0.01) | 67 (0.02) |
Weight decreased | 9 (0.08) | 35 (0.25) | 149 (0.58) | 0 | 174 (0.33) | 287 (0.15) | 705 (0.24) |
Weight increased | 2 (0.02) | 12 (0.09) | 18 (0.07) | 1 (0.35) | 22 (0.04) | 45 (0.02) | 109 (0.04) |
Wheezing | 14 (0.13) | 92 (0.67) | 63 (0.24) | 0 | 231 (0.43) | 517 (0.27) | 948 (0.32) |
White blood cell count decreased | 0 | 9 (0.07) | 6 (0.02) | 0 | 32 (0.06) | 45 (0.02) | 102 (0.03) |
White blood cell count increased | 2 (0.02) | 17 (0.12) | 13 (0.05) | 0 | 92 (0.17) | 50 (0.03) | 205 (0.07) |
Wound | 0 | 0 | 4 (0.02) | 0 | 11 (0.02) | 42 (0.02) | 61 (0.02) |